Discovery of new genes for molar pregnancies sheds light on their increased incidence in women aged 35 and over - Research Institute of the McGill University Health Centre

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src="/o/js_bundle_config?t=1739772210085" type="text/javascript"></script> <script data-senna-track="temporary" type="text/javascript"> // <![CDATA[ // ]]> </script> <link class="lfr-css-file" data-senna-track="temporary" href="https://rimuhc.ca/o/ri-muhctheme73-theme/css/main.css?browserId=ie&themeId=rimuhctheme73_WAR_rimuhctheme73theme&languageId=en_US&b=7304&t=1732341716000" id="liferayThemeCSS" rel="stylesheet" type="text/css" /> <style data-senna-track="temporary" type="text/css"> .portlet-asset-publisher .asset-full-content img { max-width: 5000px; } .lfr-dynamic-uploader { margin-top: 100px; } .blurb-img-right img, .blurb-img-left img { max-width: 250px !important; height: auto !important; } .ri-page-anchor { display: block; position: relative; top: -80px; visibility: hidden; } /* TEXT */ .ri-resp-bullets { display: inline-block; width: 100%; } .ri-resp-bullets-1-of-1, .ri-resp-bullets-1-of-2, .ri-resp-bullets-2-of-2, .ri-resp-bullets-1-of-3, .ri-resp-bullets-2-of-3, .ri-resp-bullets-3-of-3 { margin-bottom: 0px; float: left; } .ri-resp-bullets-1-of-1{ width: 100%; } .ri-resp-bullets-1-of-3, .ri-resp-bullets-2-of-3, .ri-resp-bullets-3-of-3 { width: 33.33%; } .ri-resp-bullets-1-of-2, .ri-resp-bullets-2-of-2 { width: 50%; } .ri-resp-bullets.hide-bullets ul { list-style: none; } .ri-resp-bullets.spaced-bullets li { padding-bottom:15px; } /* added large-format */ .ri-resp-bullets.large-format .ri-resp-bullets-1-of-2, .ri-resp-bullets.large-format .ri-resp-bullets-2-of-2{ width: 50%; } .ri-resp-bullets.large-format .ri-resp-bullets-1-of-2 a, .ri-resp-bullets.large-format .ri-resp-bullets-2-of-2 a{ font-size: 22px; color: #2B2666; } @media screen and (max-width: 575px){ .ri-article .ri-resp-bullets ul.ri-resp-bullets-1-of-2:not(:last-child), .ri-article .ri-resp-bullets ul.ri-resp-bullets-1-of-3:not(:last-child), .ri-article .ri-resp-bullets ul.ri-resp-bullets-2-of-3:not(:last-child) { padding-bottom: 0px; } .ri-resp-bullets.large-format .ri-resp-bullets-1-of-2, .ri-resp-bullets.large-format .ri-resp-bullets-2-of-2{ width: 100%; } } /* */ ul.ri-resp-list { list-style: none; padding-left: 0; -webkit-column-count: 3; -moz-column-count: 3; column-count: 3; width: 100%; } @media screen and (max-width: 767px) { .ri-resp-bullets-1-of-2, .ri-resp-bullets-2-of-2, .ri-resp-bullets-1-of-3, .ri-resp-bullets-2-of-3 { width: 50%; } .ri-resp-bullets-3-of-3 { width: 100%; margin-top: 15px; } ul.ri-resp-list { -webkit-column-count: 2; -moz-column-count: 2; column-count: 2; } } @media screen and (max-width: 575px) { .ri-resp-bullets-1-of-2, .ri-resp-bullets-2-of-2, .ri-resp-bullets-1-of-3, .ri-resp-bullets-2-of-3 { float: none; width: 100%; } .ri-resp-bullets-3-of-3 { margin-top: 0px; } ul.ri-resp-list { -webkit-column-count: 1; -moz-column-count: 1; column-count: 1; } } /***************** LOGO LEFT BLURB RIGHT **************/ .ri-logo-left-blurb-right-wrapper { display: flex; justify-content: space-around; padding-top: 20px; padding-bottom: 20px; } .ri-logo-left-blurb-right-right { flex-basis: 80%; } .ri-logo-left-blurb-right-left img { width: 100px; } @media only screen and (max-width: 767px) { .ri-logo-left-blurb-right-left img { width: 100px; } .ri-logo-left-blurb-right-wrapper { display: flex; flex-wrap: wrap; padding-top: 0px; padding-bottom: 0px; } .ri-logo-left-blurb-right-right { flex-basis: 100%; padding-top: 20px; } .ri-logo-left-blurb-right-right .ri-article-blurb { padding-left: 20px; } } /************** GENERAL PHOTO *****************/ .ri-photo-column { box-sizing: border-box; padding-bottom: 20px; text-align: center; /* for browsers that don't support flexbox */ display: block; float: left; } .ri-photo-row .ri-photo-column:not(:last-of-type) { margin-right: 2%; } .ri-photo-row { display: -ms-flexbox; /* IE10 */ display: flex; -ms-flex-wrap: wrap; /* IE10 */ flex-wrap: wrap; padding: 0; } .ri-photo-column img { width: 100% !important; height: auto !important; } /************************** 1 full-width image **************************/ .ri-photo-1-column { width: 100%; } @media screen and (max-width: 375px) { .ri-photo-1-column { padding: 0; } } /************************** 2 images **************************/ .ri-photo-1-2-column { -ms-flex: 49%; /* IE10 */ flex: 49%; max-width: 49%; } @media screen and (max-width: 480px) { .ri-photo-1-2-column { -ms-flex: 100%; flex: 100%; max-width: 100%; } } @media screen and (max-width: 480px) { .ri-photo-row .ri-photo-column.ri-photo-1-2-column:not(:last-of-type) { margin-right: 0; } } /************************** 3 images **************************/ .ri-photo-1-3-column { -ms-flex: 32%; /* IE10 */ flex: 32%; max-width: 32%; } @media screen and (max-width: 575px) { .ri-photo-row .ri-photo-column.ri-photo-1-3-column { -ms-flex: 100%; flex: 100%; max-width: 100%; margin-right: 0; } } /************************** 4 images **************************/ .ri-photo-1-4-column { -ms-flex: 23.5%; /* IE10 */ flex: 23.5%; max-width: 23.5%; } @media screen and (max-width: 575px) { .ri-photo-1-4-column { -ms-flex: 49%; /* IE10 */ flex: 49%; max-width: 49%; } } @media screen and (max-width: 575px) { .ri-photo-row .ri-photo-column.ri-photo-1-4-column:nth-child(even) { margin-right: 0; } } @media screen and (max-width: 375px) { .ri-photo-row .ri-photo-column.ri-photo-1-4-column { -ms-flex: 100%; /* IE10 */ flex: 100%; max-width: 100%; margin-right: 0; } } /* ********************************** Pop up ************************************* */ .ri-modal-container { position: fixed; z-index: 101; top: 25vh; left: 0; text-align: center; width: 100%; display: block; visibility: hidden; } .ri-modal-content { padding: 4px; background: #ddd; border-radius: 5px; position: relative; display: inline-block; margin: 0 auto; } .ri-modal-content img { display: block; } .ri-modal-shade { position: fixed; z-index: 100; top: 0; left: 0; width: 100%; height: 100%; background: rgba(0, 0, 0, 0.8); display: none; } .ri-modal-close i { position: relative; color: #ddd; font-size: 32px; } .ri-modal-close i.fa-circle { position: absolute; color: #2B2666; margin: 4px; font-size: 24px; } .ri-modal-close { position: absolute; top: 0; right: 0; border-radius: 50%; cursor: pointer; margin-top: -10px; margin-right: -10px; } .ri-photo-row img { border: 2px solid white; } @media screen and (min-width: 576px) { .ri-photo-row img.ri-modal-image:hover { border: 2px solid #2B2666; } } @media screen and (max-width: 575px) { .ri-modal-container { visibility: hidden !important; } .ri-modal-shade { display: none !important; } } .ri-article p, .ri-article li { margin: 0px; font-size: 16px; line-height: 1.7; font-family: "Open Sans", sans-serif; } .ri-article ul { margin: 0px; padding-bottom: 20px; } .ri-article ul li ul { padding-bottom: 0; } .ri-article blockquote { font-size: 20px; border-left: 5px solid #2B2666; font-family: "Open Sans", sans-serif; } .ri-article-blurb { padding-bottom: 20px; } .ri-article figure { display: table; } .ri-article figure img { display: block; } .ri-article figcaption { display: table-caption; caption-side: bottom; margin-top: -18px; padding-bottom: 20px; font-family: "Open Sans", sans-serif; font-size: 12px; } .ri-article .blurb-img-right figcaption { padding-left: 20px; } .ri-article .blurb-img-full-width figcaption, .ri-article .blurb-img-left figcaption { padding-right: 20px; } .blurb-img-full-width { padding: 0px 0 20px 0; } .blurb-img-full-width img { width: 100%; } .blurb-img-full-width figcaption { text-align: left; } .blurb-img-left { float: left; padding: 5px 20px 20px 0; } .blurb-img-right { float: right; padding: 5px 0 20px 20px; } .ri-article-card { /* for browsers that don't support flexbox */ /*display: block; float: left;*/ width: 100%; display: -webkit-box; display: -ms-flexbox; display: flex; -webkit-box-orient: horizontal; -webkit-box-direction: normal; -ms-flex-direction: row; flex-direction: row; padding: 0px 0 20px 0; } p.ri-card-blurb { font-size: 12px; padding-right: 15px; padding-top: 6px; } .ri-article-card-photo { -ms-flex-preferred-size: max-content; flex-basis: max-content; -ms-flex: 0 1 auto; } .ri-article-card-photo img { max-width: initial !important; } .ri-article-card-deets.spread-out-virtically { /* for browsers that don't support flexbox */ display: block; display: -webkit-box; display: -ms-flexbox; display: flex; } .ri-article-card-deets.spread-out-virtically { -webkit-box-orient: vertical; -webkit-box-direction: normal; -ms-flex-direction: column; flex-direction: column; -webkit-box-pack: space-evenly; -ms-flex-pack: space-evenly; justify-content: space-evenly; } @supports (-ms-accelerator: true) { /* Edge only */ .ri-article-card-deets.spread-out-virtically { justify-content: space-around; /* you can also add some other adjustments to size, margins etc to get the same positioning */ } } .ri-article-card.img-right .ri-article-card-photo { -webkit-box-ordinal-group: 3; -ms-flex-order: 2; order: 2; } .ri-article-card.img-right .ri-article-card-deets { -webkit-box-ordinal-group: 2; -ms-flex-order: 1; order: 1; } .ri-article-card.img-right .ri-article-card-deets { padding: 10px 20px 10px 0px; } .ri-article-card.img-right.card-bg .ri-article-card-deets { padding-left: 20px; } .ri-article-card-deets { -ms-flex: 0 1 auto; padding: 10px 20px 10px 20px; } .ri-article-card.card-bg .ri-article-card-deets { background: #eee; } .deet-label { background: #2B2666; color: white; padding: 2px 4px; font-weight: bold; font-family: "d-dindin-bold"; line-height: 1.4; margin-right: 5px; text-transform: uppercase; } /******************/ .ri-article-img-text { display: -webkit-box; display: -ms-flexbox; display: flex; -webkit-box-align:center; -ms-flex-align:center; align-items:center; text-align:center; padding-bottom:20px; } .ri-article-img-text .ri-article-blurb{ padding-left:20px; } /******************/ .portlet-asset-publisher .header-title { font-family: "d-dindin-bold"; color: #2B2666; } .header-back-to a { font-size: 24px; color: #2B2666; } .header-back-to a:hover { color: #425d86; } .ri-article-section-header { margin-top: 0; border-bottom: 4px solid #2B2666; padding-bottom: 10px; margin-bottom: 20px; font-family: "d-dindin-bold"; color: #2B2666; font-size: 26px; } .section-subtitle { font-family: "d-dindin-bold"; font-size: 18px; padding-bottom: 20px; } .ri-article-btn-group { display: inline-block; width: 100%; padding: 0px 0px 15px 0px; } .ri-article-btn-cta { float: left; margin: 0; padding: 0px 5px 5px 0; } .ri-article-document-link { text-align: center; } .ri-article-document-link span { font-size: 24px; font-family: "d-dindin-bold"; color: white; background: #2B2666; padding: 5px 20px; text-decoration: none; text-transform: uppercase; display: block; position: relative; } .ri-article-document-link span i { padding-right: 10px; } .ri-article-document-link:hover { text-decoration: none; } .ri-article-document-link:hover span { background: #002967; } /* When the detail content is too big, collapse it so that it is displayed below the image */ .ri-article-card.collapse-overflow { -webkit-box-orient: vertical; -webkit-box-direction: normal; -ms-flex-direction: column; flex-direction: column; } .ri-article-card.collapse-overflow .ri-article-card-photo { padding-bottom: 20px; } .ri-article-card.collapse-overflow .ri-article-card-deets { padding: 0px; } .ri-article-card.collapse-overflow.card-bg .ri-article-card-deets { background: #fff; } .ri-article-card.collapse-overflow.img-right .ri-article-card-photo { -webkit-box-ordinal-group: 2; -ms-flex-order: 1; order: 1; } .ri-article-card.collapse-overflow.img-right .ri-article-card-deets { -webkit-box-ordinal-group: 3; -ms-flex-order: 2; order: 2; } @media screen and (max-width: 480px) { .blurb-img-left, .blurb-img-right { padding: 0; width: 100%; padding-bottom: 20px; } .blurb-img-left.mobile-center img, .blurb-img-right.mobile-center img { margin: 0 auto; } .ri-article figure img { /*margin: 0 auto;*/ } .ri-article figcaption { margin-top: 0; } .ri-article .blurb-img-right figcaption { padding-left: 0px; } .ri-article .blurb-img-full-width figcaption, .ri-article .blurb-img-left figcaption { padding-right: 0px; } } @media screen and (min-width: 576px) { .ri-article-card-photo { text-align: center; } } /******************** PAGE COMPONENTS *******************************/ .ri-section-header { font-family: "d-dindin-bold"; color: #2B2666; border-bottom: 4px solid #2B2666; font-size: 26px; padding-top: 25px; padding-bottom: 10px; margin-top: 0; margin-bottom: 15px; } .ri-section-header.no-top-space { padding-top: 0; } @media only screen and (max-width: 1024px) { .portlet-journal-content .journal-content-article img.ri-page-banner { max-width: 110%; margin-left: -5%; width: 110%; } } .ri-article-list { color: #2B2666; } .ri-article-list li a { font-size: 22px; color: #2B2666; } @media only screen and (max-width: 479px) { .ri-article-list { padding-left: 20px; } .ri-article-list li a { font-size: 18px; } } /* ************ Business Card Styles *************** */ .ri-business-cards { font-family: "Open Sans", sans-serif; } .ri-business-cards table { margin: 0 auto; background: #efefef; } .ri-business-cards .col-md-6 { padding: 0; padding: 10px; } .ri-business-cards .pi-card-right { padding: 10px 10px 0px 10px; min-width: 190px; } .ri-business-cards .pi-card-right h5 { margin: 0; padding: 0; color: #3f81c3; font-weight: 700; font-size: 14px; line-height: 18px; } .ri-business-cards .pi-card-right h5 { margin: 0; padding: 0; margin-bottom: 2px; } .ri-business-cards .ri-rkeywords p { margin: 0; padding: 0; font-size: 12px; line-height: 14px; padding-bottom: 5px; } .ri-business-cards .pi-card-left img { max-height: 170px; vertical-align: top; } .ri-business-cards p.ri-rtitle { margin: 0; padding: 0; padding-bottom: 2px; font-weight: 700; font-size: 14px; } .ri-business-cards .ri-card-link { color: #337ab7; } @media only screen and (max-width: 479px) { .ri-business-cards .ri-card-link a { font-size: 14px; margin: 0 0 4px; } .ri-business-cards p.ri-card-link { font-size: 14px; } .ri-business-cards .pi-card-right h5 { margin-bottom: 2px; } .ri-business-cards p.ri-rtitle { padding-bottom: 0px; } p.ri-card-blurb { font-size: 12px; width: 160px; } } @media only screen and (min-width: 480px) { .ri-business-cards .pi-card-right { min-width: 250px; } } @media only screen and (max-width: 360px) { .ri-business-cards p.ri-rtitle { font-size: 12px !important; } } /***************************** Table ****************************/ .ri-responsive-table { margin: 0 auto; padding-bottom: 30px; /* max-width: 900px; */ font-family: "Open Sans", sans-serif; font-size: 14px; line-height: 20px; } .ri-table-sub-title { margin: 10px auto; font-size: 20px; line-height: 24px; /* max-width: 900px; */ font-family: "d-dinregular"; padding-left: 2px; color: #2B2666; } @media screen and (max-width: 580px) { .ri-responsive-table { font-size: 16px; line-height: 22px; } } .ri-responsive-table .table-inner { margin: 0; width: 100%; box-shadow: 0px 0px 5px 3px rgba(206, 206, 206, 0.2); display: table; table-layout: fixed; } @media screen and (max-width: 580px) { .ri-responsive-table .table-inner { display: block; } } .ri-table-row { display: table-row; background: #e0ebf5; color: #000; } .ri-table-row:nth-of-type(odd) { background: #fff; } .ri-table-row.header { font-weight: 600; color: #2B2666; background: #fff; text-transform: uppercase; font-family: "d-dindin-bold"; } @media screen and (max-width: 580px) { .ri-table-row { padding: 10px 16px; display: block; background: #fff; } .ri-table-row:nth-of-type(odd) { background: #f9f9f9; } .ri-table-row.header { margin: 0 -1px; padding: 0; height: 6px; background: #e0ebf5; } .ri-table-row.header .cell { display: none; } .ri-table-row .cell:first-of-type { font-weight: 600; } .ri-table-row .cell a { text-decoration: solid !important; } .ri-table-row .cell:hover a { cursor: pointer; } .ri-table-row .cell:before { margin-bottom: 3px; content: attr(data-title); min-width: 98px; font-size: 12px; line-height: 12px; font-weight: bold; text-transform: uppercase; color: #2B2666; display: block; } } .ri-table-row .cell { padding: 6px 12px; display: table-cell; } @media screen and (max-width: 580px) { .ri-table-row .cell { padding: 0px 16px; display: block; } } /* https://rimuhc.atlassian.net/browse/PUBLICWEB-489 */ .ri-responsive-table.minimal-style .table-inner { box-shadow: none; } .minimal-style .ri-table-row .cell { padding: 0; } @media screen and (max-width: 580px){ .minimal-style .ri-table-row .cell:first-of-type { font-weight: 500; margin-bottom: 20px; } .minimal-style .ri-table-row:nth-of-type(odd) { background: #fff; } .ri-responsive-table.minimal-style { font-size: 14px; line-height: 18px; } .minimal-style .ri-table-row { padding: 0; } } /* END table /* PUBLICWEB-477 - HOME PAGE SPRINT 1 RELEASE */ /* COVID-19 Banner */ .ri-home-page-layout .special-announcement-banner { background: blue; } .ri-home-page-layout .special-announcement-banner { background: #2B2666; height: 35px; width: 100%; display: -webkit-box; display: -ms-flexbox; display: flex; -webkit-box-orient: vertical; -webkit-box-direction: normal; -ms-flex-direction: column; flex-direction: column; -webkit-box-pack: center; -ms-flex-pack: center; justify-content: center; margin-bottom: 25px; } @media (max-width: 767px) { .ri-home-page-layout .special-announcement-banner { height: 60px; padding: 0 10px; } } .ri-home-page-layout .special-announcement-banner p { color: white; text-align: center; margin: 0; font-family: "Open Sans", sans-serif; } .ri-home-page-layout .special-announcement-banner p a { text-decoration: underline; color: #ffffff; } .ri-home-page-layout .special-announcement-banner p a:hover { color: #a1cdff; } /* CAREER CALL TO ACTION */ .call-to-action-wrapper .cta-btn-yyt { font-size: 20px; width: 200px; margin: 10px auto; text-align: center; border: 4px solid #2B2666; font-family: "d-dindin-bold"; text-transform: uppercase; display: block; } .call-to-action-wrapper .cta-btn-yyt.large { width: 270px; } .call-to-action-wrapper .cta-btn-yyt:hover { border: 4px solid #2B2666; background: #2B2666; color: #fff; } .call-to-action-wrapper a { color: #2B2666; text-decoration: none; } .call-to-action-wrapper { text-align: center; padding: 20px 20px 40px 20px; } .call-to-action-wrapper h2 { font-family: "d-dindin-bold"; color: #2B2666; margin-top: 0px; margin-bottom: 0px; } .call-to-action-wrapper p { font-size: 16px; font-family: "Barlow", sans-serif; font-weight: 500; } /* *********** CSS from program news/events section ***************** */ .cta-w-icon-wrapper { display: flex; justify-content: space-between; margin-bottom: 15px; } .cta-w-icon-middle { flex-basis: 50%; } .cta-w-icon-left img, .cta-w-icon-middle p { padding-right: 20px; } .cta-w-icon-right { flex-basis: 200px; min-width: 200px; } .cta-w-icon-right a { font-size: 20px; padding: 6px 0; width: 100%; margin: 0; text-align: center; background: #2B2666; font-family: "d-dindin-bold"; text-transform: uppercase; display: block; color: white; } .cta-w-icon-right.respect-written-case a { text-transform: initial; } .cta-w-icon-left { padding-right: 15px; } @media only screen and (max-width: 767px) { .cta-w-icon-wrapper { display: flex; flex-wrap: wrap; margin-bottom: 30px; } .cta-w-icon-left img, .cta-w-icon-middle p { padding-right: 0px; } .cta-w-icon-left, .cta-w-icon-middle p { padding-bottom: 20px; } .cta-w-icon-right { flex-basis: 100%; order: 2; } .cta-w-icon-left { flex-basis: 100%; order: 1; text-align: center; padding-right: 0px; } .cta-w-icon-middle { flex-basis: 100%; order: 3; } .cta-w-icon-right a { width: 200px; margin: 0 auto 20px auto; } } @media only screen and (max-width: 767px) { .cta-w-icon-wrapper .landing-button { margin: 10px 0 10px 0; } } .cta-w-icon-wrapper .landing-button a { color: white; } @media only screen and (max-width: 479px) { .cta-w-icon-wrapper .landing-button { width: 75%; } } /* *********** CSS from program contact section ***************** */ .ri-rcards { font-family: 'Open Sans', sans-serif; display: flex; flex-wrap: wrap; } .ri-rcards .ri-rcard { flex-basis: 50%; display: flex; background: #efefef; } .pi-card-left { flex-basis: 140px; } .pi-card-right { padding: 10px 10px 0px 10px; } .pi-card-right h5 { margin: 0; padding: 0; color: #3f81c3; font-weight: 700; font-size: 14px; line-height: 18px; } .pi-card-right h5 { margin: 0; padding: 0; margin-bottom: 10px; } .ri-rkeywords p { margin: 0; padding: 0; font-size: 12px; line-height: 14px; padding-bottom: 5px; } .pi-card-left img { vertical-align: top; } p.ri-rtitle { margin: 0; padding: 0; padding-bottom: 10px; font-weight: 700; } .ri-card-link { color: #337ab7; } @media only screen and (max-width: 767px) { .ri-rcards { display: block; } .ri-rcards .ri-rcard { max-width: 450px; margin: 0 auto 20px auto; } } @media only screen and (min-width: 768px) { .ri-rcards .ri-rcard:nth-child(1) { margin-right: 15px; } .ri-rcards .ri-rcard:nth-child(2) { margin-left: 15px; } } @media only screen and (max-width: 479px) { .ri-card-link a { font-size: 16px; margin: 0 0 4px; } .pi-card-right h5 { margin-bottom: 2px; } } @media only screen and (min-width: 480px) { .pi-card-right {} } @media only screen and (max-width: 360px) { p.ri-rtitle { font-size: 12px !important; } } .ri-ddm { font-family: 'Open Sans', sans-serif; display: flex; } .ri-ddm .ri-zul { flex-basis: 50%; display: flex; background: #efefef; } .ri-bdt-left { /*flex-basis: 140px;*/ } .ri-bdt-right { padding: 10px 10px 0px 10px; } .ri-bdt-right h5 { margin: 0; padding: 0; color: #3f81c3; font-weight: 700; font-size: 14px; line-height: 18px; } .ri-bdt-right h5 { margin: 0; padding: 0; margin-bottom: 10px; } .ri-bdt-left img { width: 140px; vertical-align: top; } .portlet-journal-content .journal-content-article .ri-bdt-left img { max-width: unset; } p.ri-bdt-title { margin: 0; padding: 0; padding-bottom: 10px; font-weight: 700; font-size: 14px; } .ri-bdt-email-link { color: #337ab7; font-size: 14px; } @media only screen and (max-width: 767px) { .ri-ddm { display: block; } .ri-ddm .ri-zul { max-width: 450px; margin: 0 auto 20px auto; } } @media only screen and (min-width: 768px) { .ri-ddm .ri-zul:nth-child(1) { margin-right: 15px; } .ri-ddm .ri-zul:nth-child(2) { margin-left: 15px; } } @media only screen and (max-width: 479px) { .ri-bdt-email-link a { font-size: 16px; margin: 0 0 4px; } .ri-bdt-right h5 { margin-bottom: 2px; } } @media only screen and (min-width: 480px) { .ri-bdt-right {} } @media only screen and (max-width: 360px) { p.ri-bdt-title { font-size: 12px !important; } .ri-bdt-right h5 { font-size: 12px !important; } } /* ************ RI Home page news ****** */ .ri-glf { display: flex; flex-direction: column; flex-wrap: wrap; justify-content: space-between; padding: 0; font-family: "Barlow", sans-serif; height: 440px; } .asset-edit-icon { display: none; } .controls-visible .asset-edit-icon { display: block; } .ri-ttv a h4 { margin: 0; /*reset*/ padding: 0; color: #000; font-size: 16px; font-weight: 500; } .ri-ttv a { text-decoration: none; display: flex; } .ri-ttv a:hover h4 { color: #004cbd; } .ri-ttv p { margin: 0; /*reset*/ padding: 0; color: #302c44; font-size: 14px; line-height: 16px; padding-top: 4px; font-weight: 200; } /* */ .ri-ttv a:hover .ri-fjw .ri-fjw-inner { width: 100%; } .ri-fjw { width: 100%; background: #f3f3f3; } .ri-fjw-inner { width: 0; height: 3px; transition: width 0.4s; transition-timing-function: ease-in; background: #2B2666; } .brightness { background-color: white; display: inline-block; } .ri-ttv a:hover .brightness img { opacity: 0.5; } /* *************************************** */ .ri-xlg { display: flex; justify-content: space-between; width: 100%; padding-top: 36px; padding-bottom: 12px; } .ri-xlg h2 { font-family: "d-dindin-bold"; color: #000; font-size: 22px; line-height: 24px; margin: 0; } @media (max-width: 991px) { .ri-xlg { padding: 36px 15px 12px 15px; } } /* ****************** */ .ri-jwi { text-align: right; width: 100%; padding-top: 24px; padding-bottom: 24px; } .ri-jwi p { text-align: right; margin: 0; padding-right: 36px; } .ri-jwi p a { color: #2B2666; font-size: 16px; font-weight: 700; text-decoration: none; } .ri-jwi p a:hover { color: #000; } @media (max-width: 991px) { .ri-glf { padding: 0px 12px; } .ri-ttv { width: 50%; /*padding-bottom: 24px;*/ } .ri-ttv:nth-child(1), .ri-ttv:nth-child(2), .ri-ttv:nth-child(3) { padding-right: 12px; } .ri-ttv:nth-child(4), .ri-ttv:nth-child(5), .ri-ttv:nth-child(6) { padding-left: 12px; } .ri-ttv img { width: 160px; } .ri-ttv a h4 { /*margin-bottom:2px; height: 100px; overflow: hidden;*/ } .ri-qfr { display: flex; flex-direction: column; justify-content: space-between; padding-left: 10px; } .ri-jwi { padding: 12px; } } @media (min-width: 992px) { .ri-glf { height: 335px; } .ri-ttv { max-width: 322px; } .ri-ttv:nth-child(1), .ri-ttv:nth-child(2) { max-width: 275px; margin-right: 25px; } /*.ri-ttv:nth-child(6) { display:none; }*/ .ri-ttv a { display: block; } .ri-ttv a h4 { font-size: 18px; } .ri-ttv:nth-child(1) h4, .ri-ttv:nth-child(2) h4 { padding-top: 6px; height: 114px; overflow: hidden; } .ri-ttv:nth-child(3) h4 { padding-top: 0px; } .ri-ttv .brightness { display: none; } .ri-ttv:nth-child(1) .brightness, .ri-ttv:nth-child(2) .brightness { display: block; } } @media (max-width: 767px) { .ri-glf { height: auto; } .ri-ttv { width: 100%; padding-bottom: 36px; } .ri-ttv:nth-child(1), .ri-ttv:nth-child(2), .ri-ttv:nth-child(3) { padding-right: 0px; } .ri-ttv:nth-child(4), .ri-ttv:nth-child(5), .ri-ttv:nth-child(6) { padding-left: 0px; } .ri-ttv img { width: 200px; } .ri-ttv a h4 { font-size: 22px; } .ri-ttv p { font-size: 20px; line-height: 24px; } .ri-jwi { padding: 0px 0px 48px 12px; } .ri-jwi p { padding-right: 12px; } } @media (max-width: 480px) { .ri-ttv img { width: 120px; } .ri-ttv a h4 { font-size: 16px; } .ri-ttv p { font-size: 16px; line-height: 20px; } } @media (max-width: 360px) { .ri-ttv a { flex-direction: column; } .ri-qfr { padding-left: 0px; padding-top: 10px; } } /* ****** New Title and Link css ***** */ .ri-gys { padding-top: 36px; padding-bottom: 12px; } .ri-gys h2 { font-family: "d-dindin-bold"; color: #000; font-size: 22px; line-height: 24px; margin: 0; } .ri-azw p { text-align: right; padding-top: 24px; padding-bottom: 24px; } .ri-azw p { text-align: right; margin: 0; padding-right: 36px; } .ri-azw p a { color: #2B2666; font-size: 16px; font-weight: 700; text-decoration: none; } /* ****** Added for cardio equipment list ******* */ .ri-article .ri-subtitle-hbb { margin: 60px auto 0 auto; font-family: "d-dindin-bold"; color: #2B2666; border-bottom: 1px solid #2B2666; font-size: 20px; padding-top: 25px; padding-bottom: 4px; } @media only screen and (max-width: 600px) { .ri-article .ri-subtitle-hbb { margin: 40px auto 0 auto; } } .ri-article .ri-subtitle-hbb.no-top-spacing { margin: 0px auto 0 auto; } // SP73 TODO // This is a temporary fix // It is better to fix this by setting the portlet settings .portlet-content{ .portlet-title-text { display: none; } } .portlet-content{ .portlet-title-text.portlet-title-editable { display: none; } } /* 7.3 Migration: enforcing old link colour */ a { color: #337ab7; text-decoration: none; } a:hover, a:focus { color: #23527c; text-decoration: underline; } /* Search page */ div#_com_liferay_portal_search_web_portlet_SearchPortlet_facetNavigation { display: none; } .search-layout span.taglib-asset-tags-summary { display: none; } @media (min-width: 768px){ .search-layout .col-md-9.result { flex: 0 0 100%; max-width: 100%; } } /*** Tech platforms revamp March 2021 **********/ .ri-blockquote { padding-bottom: 20px; } .ri-blockquote-blurb { padding-left: 20px; } .ri-blockquote-line { border-left: 2px solid #e0e0e0; } .ri-blockquote-name { font-weight: bold; padding-left: 22px; padding-top: 15px; } .ri-header-bkv { color: #00509a; font-size: 1.5rem; font-weight: 600; } /*** END 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width: 200px; } .ri-mega-menu.work-with-us .ri-mm-heading-text { width: 920px; } .ri-mega-menu.work-with-us .ri-mm-content .ri-mm-section:nth-child(1) { width: 670px; } .ri-mega-menu.work-with-us .ri-mm-content .ri-mm-section:nth-child(2) { width: 250px; } .ri-mega-menu.work-with-us.fr .ri-mm-heading-text { width: 1010px; } .ri-mega-menu.work-with-us.fr .ri-mm-content .ri-mm-section:nth-child(1) { width: 720px; } .ri-mega-menu.work-with-us.fr .ri-mm-content .ri-mm-section:nth-child(2) { width: 290px; } /*# sourceMappingURL=ri-mega-menu-main.css.map */ </style> <div class="ri-mega-menu about-us"><div class="ri-mm-heading-bar"> </div><div class="ri-mm-content"><div class="ri-mm-section"><div class="ri-mm-section-inner"><nav><ul><li class="mm-level-1"><a href="/annual-reports"><span>ANNUAL REPORTS</span></a></li><li class="mm-level-2" style="position: relative;"><div class="image-with-shadow"><a target="_self" href="/annual-report/2023/home"><picture data-fileentryid="17327477"><source media="(max-width:89px)" srcset="/o/adaptive-media/image/17327477/Thumbnail-128x128/ar-2024-megamenu-en.jpg?t=1729170435912" /><source media="(max-width:140px) and (min-width:89px)" srcset="/o/adaptive-media/image/17327477/Preview-1000x0/ar-2024-megamenu-en.jpg?t=1729170435912" /><img src="/documents/10803/17086967/ar-2024-megamenu-en.jpg/5c333c76-f3a0-6f44-579f-07a0c7f1307b?t=1729170435912" /></picture> </a><div class="hover-layer"> </div><a target="_self" href="/annual-report/2024/home"> </a><div class="year-layer"><a target="_self" href="/annual-report/2024/home"><span style="color: #37536b;">2024</span></a></div><a target="_self" href="/annual-report/2024/home"> </a></div></li><li class="mm-level-2" style="position: relative;"><a href="/annual-reports"><span>See All</span></a></li></ul></nav></div></div><div class="ri-mm-section"><div class="ri-mm-section-inner"><nav><ul><li class="mm-level-1"><a href="/about-us"><span>ABOUT US</span></a></li><li class="mm-level-2"><a href="/message-from-the-executive-director"><span>Message from the Executive Director</span></a></li><li class="mm-level-2"><a href="/the-ri-muhc-in-numbers"><span>The Institute in numbers</span></a></li><li class="mm-level-2"><a href="/our-vision-and-mission"><span>2030 Vision</span></a></li><li class="mm-level-2"><a href="/about-us/oversight"><span>Oversight</span></a></li><li class="mm-level-2"><a href="/about-us/equity-diversity-inclusion"><span>Equity, diversity, inclusion (EDI)</span></a></li><li class="mm-level-2"><a href="/about-us/research-data-management-strategy"><span>Research Data Management Strategy</span></a></li><li class="mm-level-2"><a href="/milestones"><span>Milestones</span></a></li><li class="mm-level-2"><a href="/ri-muhc-sites"><span>RI-MUHC Sites</span></a></li><li class="mm-level-2"><a href="/administrative-services"><span>Administrative Services</span></a></li><li class="mm-level-2"><a href="/your-support"><span>Your Support</span></a></li></ul></nav></div></div><div class="ri-mm-section"><div class="ri-mm-section-inner"><p>The Research Institute of the McGill University Health Centre (RI-MUHC) brings together pediatric and adult research programs, accelerating the translation of biomedical research to improve human health.</p></div></div></div></div> </div> </div> </div> </div> </div> </section> </div> </li> <li class="ri-h ri-h-link"> <a class = "l1-link" href='https://rimuhc.ca/research' >Research</a> <div class="portlet-boundary portlet-boundary_com_liferay_journal_content_web_portlet_JournalContentPortlet_ portlet-static portlet-static-end portlet-barebone portlet-journal-content " id="p_p_id_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_MEGA_MENU_ID_1_"> <span id="p_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_MEGA_MENU_ID_1"></span> <section class="portlet" 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width: 200px; } .ri-mega-menu.work-with-us .ri-mm-heading-text { width: 920px; } .ri-mega-menu.work-with-us .ri-mm-content .ri-mm-section:nth-child(1) { width: 670px; } .ri-mega-menu.work-with-us .ri-mm-content .ri-mm-section:nth-child(2) { width: 250px; } .ri-mega-menu.work-with-us.fr .ri-mm-heading-text { width: 1010px; } .ri-mega-menu.work-with-us.fr .ri-mm-content .ri-mm-section:nth-child(1) { width: 720px; } .ri-mega-menu.work-with-us.fr .ri-mm-content .ri-mm-section:nth-child(2) { width: 290px; } /*# sourceMappingURL=ri-mega-menu-main.css.map */ </style> <div class="ri-mega-menu research"><div class="ri-mm-heading-bar"> </div><div class="ri-mm-content"><div class="ri-mm-section"><div class="ri-mm-section-inner"><nav><ul><li class="mm-level-1"><a href="/programs"><span>RESEARCH PROGRAMS</span></a></li><li class="mm-level-2" style=""><a href="/brain-repair-and-integrative-neuroscience-program"><img style="width: 35px;float: left; margin-right: 10px;margin-top: 3px;" src="/documents/10803/762018/BRaIN.jpg/49138c90-df95-df97-4ff7-e0950ac3c4a0?t=1572984299028" /><span><b>BRaIN</b> | Brain Repair and Integrative Neuroscience Program</span></a></li><li class="mm-level-3 extra-indent"><a href="/brain-themes"><span>Themes</span></a><br /><a href="/research/programs/brain/researchers"><span>Researchers</span></a><br /><a href="/brain-contact-us"><span>Contact</span></a></li><li class="mm-level-2" style="max-width: 255px;margin-top: 15px;"><a href="/cancer-research-program"><img style="width: 35px;float: left; margin-right: 10px;margin-top: 3px;" src="/documents/10803/762018/CRP.jpg/c032d453-e4a2-483b-5b33-88f4bbec0b23?t=1572984298887" /><span><b>CRP</b> | Cancer Research Program</span></a></li><li class="mm-level-3 extra-indent"><a href="/cancer-themes"><span>Themes</span></a><br /><a href="/research/programs/crp/researchers"><span>Researchers</span></a><br /><a href="/cancer-contact-us"><span>Contact</span></a></li><li class="mm-level-2" style="margin-top: 15px;"><a href="/cardiovascular-health-across-the-lifespan-program"><img style="width: 35px;float: left; margin-right: 10px;margin-top: 3px;" src="/documents/10803/762018/CHAL.jpg/be09b6c1-5644-8367-f1d6-9c23c90d082c?t=1572984298684" /><span><b>CHAL</b> | Cardiovascular Health Across the Lifespan Program</span></a></li><li class="mm-level-3 extra-indent"><a href="/chal-themes"><span>Themes</span></a><br /><a href="/research/programs/chal/researchers"><span>Researchers</span></a><br /><a href="/chal-contact-us"><span>Contact</span></a></li></ul></nav></div><div class="ri-mm-section-inner"><nav><ul><li class="mm-level-2 spacing-top" style=""><a href="/child-health-and-human-development-program"><img style="width: 35px;float: left; margin-right: 10px;margin-top: 3px;" src="/documents/10803/762018/CHHD.jpg/9b87afe5-c279-92f1-052f-8e34ee84fd57?t=1572984299762" /><span><b>CHHD</b> | Child Health and Human Development Program</span></a></li><li class="mm-level-3 extra-indent"><a href="/chhd-themes"><span>Themes</span></a><br /><a href="/research/programs/chhd/researchers"><span>Researchers</span></a><br /><a href="/chhd-contact-us"><span>Contact</span></a></li><li class="mm-level-2" style="margin-top: 15px;"><a href="/infectious-diseases-and-immunity-in-global-health-program"><img style="width: 35px;float: left; margin-right: 10px;margin-top: 3px;" src="/documents/10803/762018/IDIGH.jpg/a2fa3f87-292f-7c51-ae77-4988f3f8a898?t=1572984299481" /><span><b>IDIGH</b> | Infectious Diseases and Immunity in Global Health Program</span></a></li><li class="mm-level-3 extra-indent"><a href="/infectious-diseases-and-immunity-in-global-health-program"><span>Themes</span></a><br /> <a href="/research/programs/idigh/researchers"><span>Researchers</span></a><br /><a href="/idigh-contact-us"><span>Contact</span></a></li><li class="mm-level-2" style="margin-top: 15px;"><a href="/metabolic-disorders-and-complications-program"><img style="width: 35px;float: left; margin-right: 10px;margin-top: 3px;" src="/documents/10803/762018/MeDiC.jpg/377a17f9-b088-d811-3fd5-57dffef2a1d5?t=1572984299653" /><span><b>MeDiC</b> | Metabolic Disorders and Complications Program</span></a></li><li class="mm-level-3 extra-indent"><a href="/research-programs/medic-themes"><span>Themes</span></a><br /><a href="/research/programs/medic/researchers"><span>Researchers</span></a><br /><a href="/medic-contact-us"><span>Contact</span></a></li></ul></nav></div><div class="ri-mm-section-inner"><nav><ul><li class="mm-level-2 spacing-top" style="max-width: 275px;"><a href="/research/programs/surgical-interventional-sciences"><img style="width: 35px;float: left; margin-right: 10px;margin-top: 3px;" src="/documents/10803/762018/IRR.jpg/ef101f76-fbd0-ee68-fc94-6d3ddb6ab9a6?t=1572984299278" /><span><b>SIS</b> | Surgical and Interventional Sciences Program</span></a></li><li class="mm-level-3 extra-indent"><a href="/research/programs/surgical-interventional-sciences/themes"><span>Themes</span></a><br /> <a href="/research/programs/surgical-interventional-sciences/researchers"><span>Researchers</span></a><br /><a href="/research/programs/surgical-interventional-sciences/contact"><span>Contact</span></a></li><li class="mm-level-2" style="margin-top: 15px;"><a href="/translational-research-in-respiratory-diseases-program"><img style="width: 35px;float: left; margin-right: 10px;margin-top: 3px;" src="/documents/10803/762018/RESP.jpg/af6bdfdd-eb8e-a559-a9d4-67112bde6fb5?t=1572984299153" /><span><b>RESP</b> | Translational Research in Respiratory Diseases Program</span></a></li><li class="mm-level-3 extra-indent"><a href="/resp-themes"><span>Themes</span></a><br /><a href="/research/programs/resp/researchers"><span>Researchers</span></a><br /><a href="/resp-contact-us"><span>Contact</span></a></li></ul></nav></div></div><div class="ri-mm-section" style="margin-left: 0;"><div class="ri-mm-section-inner"><nav><ul><li class="mm-level-1"><span>RESEARCHER PROFILES</span></li><li class="mm-level-2"><a href="/researcher"><span>Alphabetical List</span></a></li><li class="mm-level-2"><a href="/face-to-face"><span>Face-to-Face Interviews</span></a></li><li class="mm-level-1" style="margin-top: 15px;"><a href="/research-centres"><span>RESEARCH CENTRES</span></a></li><li class="mm-level-2"><a href="/research-centres/cim"><span><strong>CIM</strong> | Centre for Innovative Medicine </span></a></li><li class="mm-level-2"><a href="/research-centres/core"><span><strong>CORE</strong> | Centre for Outcomes Research and Evaluation </span></a></li><li class="mm-level-2"><a href="/research-centres/ctb"><span><strong>CTB</strong> | Centre for Translational Biology </span></a></li></ul></nav></div></div></div></div> </div> </div> </div> </div> </div> </section> </div> </li> <li class="ri-h ri-h-link active"> <a class = "l1-link" href='https://rimuhc.ca/news-and-events' >News and Events</a> <div class="portlet-boundary portlet-boundary_com_liferay_journal_content_web_portlet_JournalContentPortlet_ portlet-static portlet-static-end portlet-barebone portlet-journal-content " id="p_p_id_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_MEGA_MENU_ID_2_"> <span id="p_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_MEGA_MENU_ID_2"></span> <section class="portlet" id="portlet_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_MEGA_MENU_ID_2"> <div class="portlet-content"> <div class="autofit-float autofit-row portlet-header"> <div class="autofit-col autofit-col-end"> <div class="autofit-section"> <div class="visible-interaction"> </div> </div> </div> </div> <div class=" portlet-content-container"> <div class="portlet-body"> <div class="" data-fragments-editor-item-id="10108-762456" data-fragments-editor-item-type="fragments-editor-mapped-item" > <div class="journal-content-article " data-analytics-asset-id="762454" data-analytics-asset-title="Mega Menu - News and Events" data-analytics-asset-type="web-content"> <style> .ri-mm-section { width: 275px; } .ri-mm-section p, .ri-mm-section li { color: #666; padding: 0; font-size: 14px; flex-shrink: 1; } .ri-mm-section p { line-height: 26px; } .ri-mm-section li { line-height: 18px; padding-bottom: 5px; } .ri-mm-section .mm-level-1 span { color: #2B2666; font-family: "d-dindin-bold"; font-size: 15px; } .ri-mm-section .mm-level-1.spacing-top { margin-top: 5px; } .ri-mm-section .mm-level-1 a:hover { text-decoration: underline; color: #0059df; } .ri-mm-section .mm-level-1 a:hover span { color: #0059df; } .ri-mm-section .mm-level-2 span { color: #2B2666; } .ri-mm-section .mm-level-2.min-h { min-height: 75px; } .ri-mm-section .mm-level-2.spacing-top { margin-top: 24px; } .ri-mm-section .mm-level-2 a:hover { text-decoration: underline; color: #63a5f1; } .ri-mm-section .mm-level-2 a:hover span { color: #63a5f1; } .ri-mm-section 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display: -webkit-box; display: -ms-flexbox; display: flex; -webkit-box-pack: center; -ms-flex-pack: center; justify-content: center; } .ri-mm-section { display: -webkit-box; display: -ms-flexbox; display: flex; -webkit-box-orient: horizontal; -webkit-box-direction: normal; -ms-flex-direction: row; flex-direction: row; font-family: "Open Sans", sans-serif; } .ri-mm-section ul { list-style-type: none; padding-left: 0; } .ri-mm-section-inner { -ms-flex-negative: 1; flex-shrink: 1; } .ri-mm-section-inner p, .ri-mm-section-inner li { -ms-flex-negative: 1; flex-shrink: 1; } .ri-mm-section-inner h4 { color: #2B2666; margin: 0; font-family: "d-dindin-bold"; font-size: 15px; line-height: 26px; } .ri-mm-section-inner li.indented { color: #666; } a.blurb-link { color: #2B2666; } a.blurb-link:hover { color: #ff537f; } .ri-event-card-table { display: table; } .ri-event-card-tr { display: table-row; } .ri-event-card-td { display: table-cell; min-width: 67px; vertical-align: top; } .ri-event-card-td.left .ri-event-card-inner { background: #2B2666; text-align: center; font-family: "d-dindin-bold"; font-size: 24px; line-height: 26px; padding: 10px; } .ri-event-card-td.left .ri-event-card-inner span { color: white; } .ri-event-card-td.right { font-family: "Open Sans", sans-serif; padding: 0 10px; } td { vertical-align: top; } td.icon { text-align: right; padding-right: 10px; } td.icon.left { width: 50px; } td.icon.right { width: 100px; } td.icon img { width: 30px; } td li.mm-level-3 { padding-bottom: 15px; } .ri-mega-menu.about-us .ri-mm-heading-text { width: 895px; } .ri-mega-menu.about-us .ri-mm-content .ri-mm-section:nth-child(1) { width: 165px; } .ri-mega-menu.about-us .ri-mm-content .ri-mm-section:nth-child(2) { width: 345px; } .ri-mega-menu.about-us .ri-mm-content .ri-mm-section:nth-child(3) { width: 385px; } .ri-mega-menu.about-us.fr .ri-mm-heading-text { width: 870px; } .ri-mega-menu.about-us.fr .ri-mm-content .ri-mm-section:nth-child(1) { width: 160px; } 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.ri-mm-section:nth-child(2) { width: 190px; } .ri-mega-menu.study-with-us .ri-mm-content .ri-mm-section:nth-child(3) { width: 160px; } .ri-mega-menu.study-with-us.fr .ri-mm-heading-text { width: 1135px; } .ri-mega-menu.study-with-us.fr .ri-mm-content .ri-mm-section:nth-child(1) { width: 620px; } .ri-mega-menu.study-with-us.fr .ri-mm-content .ri-mm-section:nth-child(2) { width: 315px; } .ri-mega-menu.study-with-us.fr .ri-mm-content .ri-mm-section:nth-child(3) { width: 200px; } .ri-mega-menu.work-with-us .ri-mm-heading-text { width: 920px; } .ri-mega-menu.work-with-us .ri-mm-content .ri-mm-section:nth-child(1) { width: 670px; } .ri-mega-menu.work-with-us .ri-mm-content .ri-mm-section:nth-child(2) { width: 250px; } .ri-mega-menu.work-with-us.fr .ri-mm-heading-text { width: 1010px; } .ri-mega-menu.work-with-us.fr .ri-mm-content .ri-mm-section:nth-child(1) { width: 720px; } .ri-mega-menu.work-with-us.fr .ri-mm-content .ri-mm-section:nth-child(2) { width: 290px; } /*# sourceMappingURL=ri-mega-menu-main.css.map */ </style> <div class="ri-mega-menu news-and-events"><div class="ri-mm-heading-bar"> </div><div class="ri-mm-content"><div class="ri-mm-section" style="padding-right: 15px;"><div class="ri-mm-section-inner"><nav><ul><li class="mm-level-1"><a href="/news-and-events"><span> NEWS </span> </a></li><li class="mm-level-2"><a href="/what-new-ri-muhc"><span>Latest News</span> </a></li><li class="mm-level-3"><a href="/-/new-discovery-could-help-protect-against-influenza"><span>New discovery could help protect against influenza</span> </a></li><li class="mm-level-3"><a href="/-/ensuring-everyone-can-fully-participate-in-research-and-healthcare"><span>Ensuring everyone can fully participate in research and healthcare</span> </a></li><li class="mm-level-3"><a href="/-/franco-carnevale-a-lifelong-commitment-to-respecting-and-elevating-children-s-voices"><span>Franco Carnevale: a lifelong commitment to respecting and elevating children’s voices</span> </a></li><li class="mm-level-2"><a href="/research-life"><span> Research Life</span> </a></li><li class="mm-level-3"><a href="/-/fall-2024-cihr-competition-results"><span>Fall 2024 CIHR competition results</span> </a></li><li class="mm-level-3"><a href="/-/fonds-de-la-recherche-de-la-fondation-j-armand-bombardier-en-sante-mere-enfant"><span>Fonds de la recherche de la Fondation J. Armand Bombardier en santé mère-enfant</span> </a></li><li class="mm-level-2"><a href="/live-funding-results"><span> Funding Results </span> </a></li><li class="mm-level-2"><a href="/honours-and-awards"><span> Honours and Awards </span> </a></li><li class="mm-level-2"><a href="/appointments"><span> Appointments </span> </a></li></ul></nav></div></div><div class="ri-mm-section"><div class="ri-mm-section-inner"><nav><ul><li class="mm-level-1"><a href="/events"><span> EVENTS </span> </a></li><li class="mm-level-2"><span> Program and Centre events </span></li><li class="mm-level-3"><a href="/research-centres/core/events"><span> Centre for Outcomes Research and Evaluation (CORE) </span> </a></li><li class="mm-level-3"><a href="/brain-events"><span> Brain Repair and Integrative Neuroscience Program </span> </a></li><li class="mm-level-3"><a href="/cancer-events"><span> Cancer Research Program </span> </a></li><li class="mm-level-3"><a href="/chal-events"><span> Cardiovascular Health Across the Lifespan Program </span> </a></li><li class="mm-level-3"><a href="/chhd-events"><span> Child Health and Human Development Program </span> </a></li><li class="mm-level-3"><a href="/idigh-events"><span> Infectious Diseases and Immunity in Global Health Program </span> </a></li><li class="mm-level-3"><a href="/medic-events"><span> Metabolic Disorders and Complications Program </span> </a></li><li class="mm-level-3"><a href="/research/programs/surgical-interventional-sciences/events"><span> Surgical and Interventional Sciences Program </span> </a></li><li class="mm-level-3"><a href="/resp-events"><span> Translational Research in Respiratory Diseases Program </span> </a></li><li class="mm-level-2"><a href="/scientific-events"><span> All Events </span> </a></li></ul></nav></div></div></div></div> </div> </div> </div> </div> </div> </section> </div> </li> <li class="ri-h ri-h-link"> <a class = "l1-link" href='https://rimuhc.ca/services' >Services</a> <div class="portlet-boundary portlet-boundary_com_liferay_journal_content_web_portlet_JournalContentPortlet_ portlet-static portlet-static-end portlet-barebone portlet-journal-content " id="p_p_id_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_MEGA_MENU_ID_3_"> <span id="p_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_MEGA_MENU_ID_3"></span> <section class="portlet" id="portlet_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_MEGA_MENU_ID_3"> <div class="portlet-content"> <div class="autofit-float autofit-row portlet-header"> <div class="autofit-col autofit-col-end"> <div class="autofit-section"> <div class="visible-interaction"> </div> </div> </div> </div> <div class=" portlet-content-container"> <div class="portlet-body"> <div class="" data-fragments-editor-item-id="10108-762464" data-fragments-editor-item-type="fragments-editor-mapped-item" > <div class="journal-content-article " data-analytics-asset-id="762462" 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class="ri-mega-menu services"><div class="ri-mm-heading-bar"> </div><div class="ri-mm-content"><div class="ri-mm-section"><div class="ri-mm-section-inner"><nav><ul><li class="mm-level-1"><span>CLINICAL RESEARCH</span></li><li class="mm-level-2"><a href="/about-clinical-trials"><span>About Clinical Trials</span></a></li><li class="mm-level-3"><a href="/mcconnell-centre-for-innovative-medicine"><span>McConnell Centre for Innovative Medicine</span></a></li><li class="mm-level-3"><a href="/patients-visitors"><span>Patients and Visitors</span></a></li><li class="mm-level-3"><a href="/industry"><span>Industry</span></a></li><li class="mm-level-3"><a href="/researchers"><span>MUHC Researchers</span></a></li><li class="mm-level-3"><a href="/research-ethics-board"><span>Centre for Applied Ethics</span></a></li><li class="mm-level-2"><span>Services for Clinical Research</span></li><li class="mm-level-3"><a href="/clinical-research/cardiopulmonary-platform"><span>Cardiopulmonary Platform</span></a></li><li class="mm-level-3"><a href="/clinical-research/clinical-trial-management"><span>Clinical Trial Management</span></a></li><li class="mm-level-3"><a href="/clinical-research/medical-imaging-platform"><span>Medical Imaging Platform</span></a></li><li class="mm-level-3"><a href="/clinical-research/mgh-mri-research-platform"><span>MGH-MRI Research Platform</span></a></li><li class="mm-level-3"><a href="/clinical-research/muhc-covid-19-biobank"><span>MUHC COVID-19 Biobank</span></a></li><li class="mm-level-3"><a href="/clinical-research/muhc-vaccine-study-centre"><span>MUHC Vaccine Study Centre</span></a></li><li class="mm-level-3"><a href="/clinical-research/specimen-collection-and-human-specimen-processing-laboratory"><span>Specimen Collection and Human Specimen Processing Laboratory</span></a></li><li class="mm-level-2"><span>Services for Clinical Innovation</span></li><li class="mm-level-3"><a href="/clinical-research/clinical-innovation-platform-clip"><span>Clinical Innovation Platform (CLIP)</span></a></li><li class="mm-level-3"><a href="/clinical-research/experimental-operating-room"><span>Experimental Operating Room</span></a></li></ul></nav></div></div><div class="ri-mm-section"><table style="height:fit-content;"><tbody><tr><td colspan="2"><ul><li class="mm-level-1"><a href="/technology-platforms"><span>TECHNOLOGY PLATFORMS</span></a></li></ul></td></tr><tr><td class="icon left" style="padding-right: 15px;padding-top: 5px;"><picture data-fileentryid="762219"><source media="(max-width:79px)" srcset="/o/adaptive-media/image/762219/Preview-1000x0/ri-mm-biobank.png?t=1572984298481" /><source media="(max-width:79px) and (min-width:79px)" srcset="/o/adaptive-media/image/762219/Thumbnail-128x128/ri-mm-biobank.png?t=1572984298481" /><img src="/documents/10803/762018/ri-mm-biobank.png" /></picture></td><td><ul><li class="mm-level-2"><a href="/biobank"><span>Biobank</span></a></li><li class="mm-level-3"><a href="/biobank-services"><span>Services</span></a></li></ul></td></tr><tr><td class="icon left"><img style="width: 40px;" src="/documents/10803/762018/ri-mm-bioinformatics.png" /></td><td><ul><li class="mm-level-2"><a href="/bioinformatics"><span>Bioinformatics</span></a></li><li class="mm-level-3"><a href="/bioinformatics-services"><span>Services</span></a><br /><a href="/bioinformatics-contact-us"><span>Contact Us</span></a></li></ul></td></tr><tr><td class="icon left" style="padding-right: 15px;"><picture data-fileentryid="762193"><source media="(max-width:67px)" srcset="/o/adaptive-media/image/762193/Preview-1000x0/ri-mm-cl3.png?t=1572984298091" /><source media="(max-width:67px) and (min-width:67px)" srcset="/o/adaptive-media/image/762193/Thumbnail-128x128/ri-mm-cl3.png?t=1572984298091" /><img src="/documents/10803/762018/ri-mm-cl3.png" /></picture></td><td><ul><li class="mm-level-2"><a href="/containment-level-3"><span>Containment Level 3</span></a></li><li class="mm-level-3"></li><li class="mm-level-3"></li></ul></td></tr><tr><td class="icon left"><img style="width: 40px;padding-top: 3px;" src="/documents/10803/762018/ri-mm-histopathology.png" /></td><td><ul><li class="mm-level-2"><a href="/histopathology"><span>Histopathology</span></a></li><li class="mm-level-3"><a href="/histopathology-services"><span>Services</span></a><br /><a href="/histopathology"><span>Contact Us</span></a></li></ul></td></tr></tbody></table><table><tbody><tr><td colspan="2" style="height: 23px;"></td></tr><tr><td class="icon right" style="padding-right: 15px;"><img style="width: 30px;" src="/documents/10803/762018/ri-mm-immuno-phenotyping.png" /></td><td><ul><li class="mm-level-2"><a href="/immunophenotyping"><span>Immunophenotyping</span></a></li><li class="mm-level-3"><a href="/immunophenotyping"><span>Services</span></a><br /><a href="/immunophenotyping"><span>Contact Us</span></a></li></ul></td></tr><tr><td class="icon right" style="padding-right: 15px;"><picture data-fileentryid="762137"><source media="(max-width:80px)" srcset="/o/adaptive-media/image/762137/Preview-1000x0/ri-mm-molecular-imaging.png?t=1572984297497" /><source media="(max-width:80px) and (min-width:80px)" srcset="/o/adaptive-media/image/762137/Thumbnail-128x128/ri-mm-molecular-imaging.png?t=1572984297497" /><img src="/documents/10803/762018/ri-mm-molecular-imaging.png" /></picture></td><td><ul><li class="mm-level-2"><a href="/molecular-imaging"><span>Molecular Imaging</span></a></li><li class="mm-level-3"><a href="/molecular-imaging-services"><span>Services</span></a><br /><a href="/molecular-imaging"><span>Contact Us</span></a></li></ul></td></tr><tr><td class="icon right" style="padding-right: 15px;"><picture data-fileentryid="762128"><source media="(max-width:128px)" srcset="/o/adaptive-media/image/762128/Thumbnail-128x128/ri-mm-proteomics.png?t=1572984297294" /><source media="(max-width:148px) and (min-width:128px)" srcset="/o/adaptive-media/image/762128/Preview-1000x0/ri-mm-proteomics.png?t=1572984297294" /><img src="/documents/10803/762018/ri-mm-proteomics.png" /></picture></td><td><ul><li class="mm-level-2"><a href="/clinical-proteomics"><span>Proteomics and Molecular Analysis</span></a></li><li class="mm-level-3"><a href="/proteomics-services"><span>Services</span></a><br /><a href="/proteomics-equipment"><span>Equipment</span></a><br /><a href="/proteomics-software"><span>Software</span></a></li></ul></td></tr><tr><td class="icon right"><img style="width: 40px;padding-top: 7px;" src="/documents/10803/762018/ri-mm-sail.png" /></td><td style="width: 135px;"><ul><li class="mm-level-2"><a href="/small-animal-imaging-labs"><span>Small Animal Imaging Labs</span></a></li><li class="mm-level-3"><a href="/sail-services"><span>Services</span></a><br /><a href="/sail-equipment"><span>Equipment</span></a><br /><a href="/sail-contact-us"><span>Contact Us</span></a></li></ul></td></tr><tr><td style="width:50px;padding-right: 10px;"> </td><td style="width: 135px;"><p class="mm-level-2"> </p></td></tr></tbody></table></div><div class="ri-mm-section"><div class="ri-mm-section-inner"><nav><ul><li class="mm-level-1"><span>CORE SERVICES</span></li><li class="mm-level-2"><a href="/services/biostatistics"><span>Biostatistics</span></a></li><li class="mm-level-2"><a target="_self" href="/services/cord"><span>Capture and Optimization of Research Data (CORD)</span></a></li><li class="mm-level-1" style="margin-top: 10px;"><span>PRECLINICAL SERVICES</span></li><li class="mm-level-2"><a href="/services/animal-resources-division"><span>Animal Resources Division (ARD)</span></a></li><li class="mm-level-1" style="margin-top: 10px;"><a href="/administrative-services"><span>ADMINISTRATIVE SERVICES</span></a></li><li class="mm-level-2"><a href="/business-development"><span>Business Development</span></a></li><li class="mm-level-2"><a href="/research-agreements-office"><span>Research Agreements Office</span></a></li><li class="mm-level-2"><a href="/research-grants"><span>Research Services</span></a></li></ul></nav></div></div></div></div> </div> </div> </div> </div> </div> </section> </div> </li> <li class="ri-h ri-h-link"> <a class = "l1-link" href='https://rimuhc.ca/study-at-the-ri-muhc' >Study with Us</a> <div class="portlet-boundary portlet-boundary_com_liferay_journal_content_web_portlet_JournalContentPortlet_ portlet-static portlet-static-end portlet-barebone portlet-journal-content " id="p_p_id_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_MEGA_MENU_ID_4_"> <span id="p_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_MEGA_MENU_ID_4"></span> <section class="portlet" id="portlet_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_MEGA_MENU_ID_4"> <div class="portlet-content"> <div class="autofit-float autofit-row portlet-header"> <div class="autofit-col autofit-col-end"> <div class="autofit-section"> <div class="visible-interaction"> </div> </div> </div> </div> <div class=" portlet-content-container"> <div class="portlet-body"> <div class="" data-fragments-editor-item-id="10108-762472" data-fragments-editor-item-type="fragments-editor-mapped-item" > <div class="journal-content-article " data-analytics-asset-id="762470" data-analytics-asset-title="Mega Menu - Study With Us" data-analytics-asset-type="web-content"> <style> .ri-mm-section { width: 275px; } .ri-mm-section p, .ri-mm-section li { color: #666; padding: 0; font-size: 14px; flex-shrink: 1; } .ri-mm-section p { line-height: 26px; } .ri-mm-section li { line-height: 18px; padding-bottom: 5px; } .ri-mm-section .mm-level-1 span { color: #2B2666; font-family: "d-dindin-bold"; font-size: 15px; } .ri-mm-section .mm-level-1.spacing-top { margin-top: 5px; } .ri-mm-section .mm-level-1 a:hover { text-decoration: underline; color: #0059df; } .ri-mm-section .mm-level-1 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.ri-mm-section:nth-child(1) { width: 165px; } .ri-mega-menu.about-us .ri-mm-content .ri-mm-section:nth-child(2) { width: 345px; } .ri-mega-menu.about-us .ri-mm-content .ri-mm-section:nth-child(3) { width: 385px; } .ri-mega-menu.about-us.fr .ri-mm-heading-text { width: 870px; } .ri-mega-menu.about-us.fr .ri-mm-content .ri-mm-section:nth-child(1) { width: 160px; } .ri-mega-menu.about-us.fr .ri-mm-content .ri-mm-section:nth-child(2) { width: 310px; } .ri-mega-menu.about-us.fr .ri-mm-content .ri-mm-section:nth-child(3) { width: 400px; } .ri-mega-menu.research .ri-mm-heading-text { width: 1125px; } .ri-mega-menu.research .ri-mm-content .ri-mm-section:nth-child(1) { width: 880px; } .ri-mega-menu.research .ri-mm-content .ri-mm-section:nth-child(2) { width: 245px; } .ri-mega-menu.research.fr .ri-mm-heading-text { width: 1155px; } .ri-mega-menu.research.fr .ri-mm-content .ri-mm-section:nth-child(1) { width: 940px; } .ri-mega-menu.research.fr .ri-mm-content .ri-mm-section:nth-child(2) { width: 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.ri-mega-menu.services.fr .ri-mm-content .ri-mm-section:nth-child(2) { width: 530px; } .ri-mega-menu.services.fr .ri-mm-content .ri-mm-section:nth-child(3) { width: 200px; } .ri-mega-menu.study-with-us .ri-mm-heading-text { width: 887px; } .ri-mega-menu.study-with-us .ri-mm-content .ri-mm-section:nth-child(1) { width: 537px; } .ri-mega-menu.study-with-us .ri-mm-content .ri-mm-section:nth-child(2) { width: 190px; } .ri-mega-menu.study-with-us .ri-mm-content .ri-mm-section:nth-child(3) { width: 160px; } .ri-mega-menu.study-with-us.fr .ri-mm-heading-text { width: 1135px; } .ri-mega-menu.study-with-us.fr .ri-mm-content .ri-mm-section:nth-child(1) { width: 620px; } .ri-mega-menu.study-with-us.fr .ri-mm-content .ri-mm-section:nth-child(2) { width: 315px; } .ri-mega-menu.study-with-us.fr .ri-mm-content .ri-mm-section:nth-child(3) { width: 200px; } .ri-mega-menu.work-with-us .ri-mm-heading-text { width: 920px; } .ri-mega-menu.work-with-us .ri-mm-content .ri-mm-section:nth-child(1) { width: 670px; } .ri-mega-menu.work-with-us .ri-mm-content .ri-mm-section:nth-child(2) { width: 250px; } .ri-mega-menu.work-with-us.fr .ri-mm-heading-text { width: 1010px; } .ri-mega-menu.work-with-us.fr .ri-mm-content .ri-mm-section:nth-child(1) { width: 720px; } .ri-mega-menu.work-with-us.fr .ri-mm-content .ri-mm-section:nth-child(2) { width: 290px; } /*# sourceMappingURL=ri-mega-menu-main.css.map */ </style> <div class="ri-mega-menu study-with-us"> <div class="ri-mm-heading-bar"> </div> <div class="ri-mm-content"> <div class="ri-mm-section"> <div class="ri-mm-section-inner"><img src="/documents/10803/762018/dcat-mm-photo.png/b3718493-6dff-5026-2efd-d8ec2affd90c?t=1572984297012" style="float:left;margin-right: 15px;" /> <p style="margin: 0;margin-right: 15px;margin-bottom: 0px;margin-top: 0px;">With world-renowned researchers, state-of-the-art facilities, a vibrant learning environment, and exceptional support to plan your career, the RI-MUHC is a great choice for graduate studies and postdoctoral training. <a class="blurb-link" href="/study-at-the-ri-muhc">Learn more</a></p> </div> </div> <div class="ri-mm-section"> <div class="ri-mm-section-inner"> <nav> <ul> <li class="mm-level-1"><span>PROSPECTIVE TRAINEES</span></li> <li class="mm-level-2"><a href="/study-at-the-ri-muhc"><span>Study With Us</span></a></li> <li class="mm-level-2"><a href="/study-at-the-ri-muhc/how-to-apply"><span>How to Apply</span></a></li> <li class="mm-level-2"><span>Join a Research Team</span></li> <li class="mm-level-3"><a href="/programs"><span>Research Programs</span></a></li> <li class="mm-level-3"><a href="/researcher"><span>Researcher Profiles</span></a></li> </ul> </nav> </div> </div> <div class="ri-mm-section"> <div class="ri-mm-section-inner"> <nav> <ul> <li class="mm-level-1"><span>CURRENT TRAINEES</span></li> <li class="mm-level-2"><a href="/study-at-the-ri-muhc/career-development"><span>Career Development</span></a></li> <li class="mm-level-2"><a href="/training-news-events"><span>News and Events</span></a></li> <li class="mm-level-2"><a href="/trainee-kudos"><span>Trainee Kudos</span></a></li> </ul> </nav> </div> </div> </div> </div> </div> </div> </div> </div> </div> </section> </div> </li> <li class="ri-h ri-h-link"> <a class = "l1-link" href='https://rimuhc.ca/careers' >Work With Us</a> <div class="portlet-boundary portlet-boundary_com_liferay_journal_content_web_portlet_JournalContentPortlet_ portlet-static portlet-static-end portlet-barebone portlet-journal-content " id="p_p_id_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_MEGA_MENU_ID_5_"> <span id="p_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_MEGA_MENU_ID_5"></span> <section class="portlet" id="portlet_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_MEGA_MENU_ID_5"> <div class="portlet-content"> <div class="autofit-float autofit-row portlet-header"> <div class="autofit-col autofit-col-end"> <div class="autofit-section"> <div class="visible-interaction"> </div> </div> </div> </div> <div class=" portlet-content-container"> <div class="portlet-body"> <div class="" data-fragments-editor-item-id="10108-762564" data-fragments-editor-item-type="fragments-editor-mapped-item" > <div class="journal-content-article " data-analytics-asset-id="762562" data-analytics-asset-title="Mega Menu - Work With Us" data-analytics-asset-type="web-content"> <style> .ri-mm-section { width: 275px; } .ri-mm-section p, .ri-mm-section li { color: #666; padding: 0; font-size: 14px; flex-shrink: 1; } .ri-mm-section p { line-height: 26px; } .ri-mm-section li { line-height: 18px; padding-bottom: 5px; } .ri-mm-section .mm-level-1 span { color: #2B2666; font-family: "d-dindin-bold"; font-size: 15px; } .ri-mm-section .mm-level-1.spacing-top { margin-top: 5px; } .ri-mm-section .mm-level-1 a:hover { text-decoration: underline; color: #0059df; } .ri-mm-section .mm-level-1 a:hover span { color: #0059df; } 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absolute; } .ri-mm-section .image-with-shadow:hover { box-shadow: 0px 0px 10px 1px #e2e2e2; } .ri-mm-section .image-with-shadow:hover .hover-layer { background: rgba(253, 254, 255, 0.85); } .ri-mm-section .image-with-shadow .year-layer { height: 100%; width: 100%; position: absolute; padding-top: 60px; padding-left: 10px; visibility: hidden; } .ri-mm-section .image-with-shadow .year-layer span { font-size: 26px; font-family: "d-dindin-bold"; } .ri-mm-section .image-with-shadow:hover .year-layer { visibility: visible; } .ri-mm-content .ri-mm-section:not(:first-child) { border-left: 1px solid #2B2666; padding-left: 20px; margin-left: 0px; } /********************************************************/ .ri-mega-menu { background: #fff; box-shadow: 2px 2px 2px rgba(0, 0, 0, 0.1); line-height: 0px; text-align: left; position: fixed; left: 0; top: 60px; width: 100%; visibility: hidden; } .ri-mega-menu.regular-dropdown { width: 275px; position: absolute; left: 0; top: 0; } 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font-size: 15px; line-height: 26px; } .ri-mm-section-inner li.indented { color: #666; } a.blurb-link { color: #2B2666; } a.blurb-link:hover { color: #ff537f; } .ri-event-card-table { display: table; } .ri-event-card-tr { display: table-row; } .ri-event-card-td { display: table-cell; min-width: 67px; vertical-align: top; } .ri-event-card-td.left .ri-event-card-inner { background: #2B2666; text-align: center; font-family: "d-dindin-bold"; font-size: 24px; line-height: 26px; padding: 10px; } .ri-event-card-td.left .ri-event-card-inner span { color: white; } .ri-event-card-td.right { font-family: "Open Sans", sans-serif; padding: 0 10px; } td { vertical-align: top; } td.icon { text-align: right; padding-right: 10px; } td.icon.left { width: 50px; } td.icon.right { width: 100px; } td.icon img { width: 30px; } td li.mm-level-3 { padding-bottom: 15px; } .ri-mega-menu.about-us .ri-mm-heading-text { width: 895px; } .ri-mega-menu.about-us .ri-mm-content .ri-mm-section:nth-child(1) { width: 165px; } .ri-mega-menu.about-us .ri-mm-content .ri-mm-section:nth-child(2) { width: 345px; } .ri-mega-menu.about-us .ri-mm-content .ri-mm-section:nth-child(3) { width: 385px; } .ri-mega-menu.about-us.fr .ri-mm-heading-text { width: 870px; } .ri-mega-menu.about-us.fr .ri-mm-content .ri-mm-section:nth-child(1) { width: 160px; } .ri-mega-menu.about-us.fr .ri-mm-content .ri-mm-section:nth-child(2) { width: 310px; } .ri-mega-menu.about-us.fr .ri-mm-content .ri-mm-section:nth-child(3) { width: 400px; } .ri-mega-menu.research .ri-mm-heading-text { width: 1125px; } .ri-mega-menu.research .ri-mm-content .ri-mm-section:nth-child(1) { width: 880px; } .ri-mega-menu.research .ri-mm-content .ri-mm-section:nth-child(2) { width: 245px; } .ri-mega-menu.research.fr .ri-mm-heading-text { width: 1155px; } .ri-mega-menu.research.fr .ri-mm-content .ri-mm-section:nth-child(1) { width: 940px; } .ri-mega-menu.research.fr .ri-mm-content .ri-mm-section:nth-child(2) { width: 215px; } .ri-mega-menu.news-and-events 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.ri-mm-section:nth-child(2) { width: 530px; } .ri-mega-menu.services.fr .ri-mm-content .ri-mm-section:nth-child(3) { width: 200px; } .ri-mega-menu.study-with-us .ri-mm-heading-text { width: 887px; } .ri-mega-menu.study-with-us .ri-mm-content .ri-mm-section:nth-child(1) { width: 537px; } .ri-mega-menu.study-with-us .ri-mm-content .ri-mm-section:nth-child(2) { width: 190px; } .ri-mega-menu.study-with-us .ri-mm-content .ri-mm-section:nth-child(3) { width: 160px; } .ri-mega-menu.study-with-us.fr .ri-mm-heading-text { width: 1135px; } .ri-mega-menu.study-with-us.fr .ri-mm-content .ri-mm-section:nth-child(1) { width: 620px; } .ri-mega-menu.study-with-us.fr .ri-mm-content .ri-mm-section:nth-child(2) { width: 315px; } .ri-mega-menu.study-with-us.fr .ri-mm-content .ri-mm-section:nth-child(3) { width: 200px; } .ri-mega-menu.work-with-us .ri-mm-heading-text { width: 920px; } .ri-mega-menu.work-with-us .ri-mm-content .ri-mm-section:nth-child(1) { width: 670px; } .ri-mega-menu.work-with-us .ri-mm-content .ri-mm-section:nth-child(2) { width: 250px; } .ri-mega-menu.work-with-us.fr .ri-mm-heading-text { width: 1010px; } .ri-mega-menu.work-with-us.fr .ri-mm-content .ri-mm-section:nth-child(1) { width: 720px; } .ri-mega-menu.work-with-us.fr .ri-mm-content .ri-mm-section:nth-child(2) { width: 290px; } /*# sourceMappingURL=ri-mega-menu-main.css.map */ </style> <div class="ri-mega-menu work-with-us"> <div class="ri-mm-heading-bar"> </div> <div class="ri-mm-content"> <div class="ri-mm-section"> <div class="ri-mm-section-inner"><img src="/documents/10803/762018/careers-mm-photo.png/fd03752f-cae4-b92e-9f82-fdb0fc283651?t=1573066498334" style="float:left;width: 230px;margin-right: 15px;margin-bottom: 0px;margin-top: 0px;" /> <p style="margin: 0;padding-right:15px;">Named one of Montreal's Top 25 Employers in three consecutive years, the Research Institute of the McGill University Health Centre (RI-MUHC) has created a workplace where people enjoy the challenges of their careers, engage in best practices and are treated with respect. <a class="blurb-link" href="/careers">Learn more</a></p> </div> </div> <div class="ri-mm-section" style="padding-right: 15px;"> <div class="ri-mm-section-inner"> <nav> <ul> <li class="mm-level-1"><span>EMPLOYMENT OPPORTUNITIES</span></li> <li class="mm-level-2"><a href="/reasons-to-work-at-the-ri-muhc"><span>Reasons to Work at the RI-MUHC</span></a></li> <li class="mm-level-2"><a href="/careers"><span>Apply Today</span></a></li> </ul> </nav> </div> </div> </div> </div> </div> </div> </div> </div> </div> </section> </div> </li> <li class="ri-h ri-h-button"> <a href = "https://portal.rimuhc.ca" target = "_blank" alt = "RI Intranet Portal"> <span class="ri-h ri-portal-link">RI PORTAL</span> </a> </li> <li class="ri-h ri-h-lang" > <div class="portlet-boundary portlet-boundary_com_liferay_site_navigation_language_web_portlet_SiteNavigationLanguagePortlet_ portlet-static portlet-static-end portlet-barebone portlet-language " 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scroll;padding-bottom: 50px;"> <div class="nav-level-1"> <table> <tr> <th class="navitem-left"> <a href="https://rimuhc.ca/about-us"> <div class = "navitem"> <span>About Us</span> </div> </a> </th> <th class="navitem-right"> <div class="dropdown-toggle-arrow"> <i class="fas fa-angle-down"></i> </div> </th> </tr> </table> <ul class="nav-level-2"> <li> <a href='https://rimuhc.ca/message-from-the-executive-director'>Message from the Executive Director</a> </li> <li> <a href='https://rimuhc.ca/the-ri-muhc-in-numbers'>The Institute in numbers</a> </li> <li> <a href='https://rimuhc.ca/our-vision-and-mission'>2030 Vision</a> </li> <li> <a href='https://rimuhc.ca/about-us/oversight'>Oversight</a> <ul> <li> <a href='https://rimuhc.ca/ri-board-of-directors'>RI-MUHC Board of Directors</a> </li> <li> <a href='https://rimuhc.ca/about-us/oversight/external-scientific-advisory-board'>External Scientific Advisory Board</a> </li> <li> <a 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href='https://rimuhc.ca/research/programs/surgical-interventional-sciences/leadership'>Leadership and Management</a> </li> <li> <a href='https://rimuhc.ca/research/programs/surgical-interventional-sciences/researchers'>Researchers</a> </li> <li> <a href='https://rimuhc.ca/research/programs/surgical-interventional-sciences/events'>Events</a> </li> <li> <a href='https://rimuhc.ca/research/programs/surgical-interventional-sciences/news'>News</a> </li> <li> <a href='https://rimuhc.ca/research/programs/surgical-interventional-sciences/contact'>Contact Us</a> </li> </ul> </li> <li> <a href='https://rimuhc.ca/translational-research-in-respiratory-diseases-program'>Respiratory Diseases</a> <ul> <li> <a href='https://rimuhc.ca/resp-themes'>Themes</a> </li> <li> <a href='https://rimuhc.ca/resp-management-committee'>Leadership and Management</a> </li> <li> <a href='https://rimuhc.ca/research/programs/resp/researchers'>Researchers</a> </li> <li> <a href='https://rimuhc.ca/resp-events'>Events</a> </li> <li> <a href='https://rimuhc.ca/resp-news'>News</a> </li> <li> <a href='https://rimuhc.ca/resp-contact-us'>Contact Us</a> </li> <li> <a href='https://rimuhc.ca/research-initiatives/cancold'>CanCOLD</a> </li> </ul> </li> </ul> </li> <li> <a href='https://rimuhc.ca/our-researchers'>Researcher Profiles</a> <ul> <li> <a href='https://rimuhc.ca/face-to-face'>Face to Face</a> </li> </ul> </li> </ul> </div> <div class="nav-level-1"> <table> <tr> <th class="navitem-left"> <a href="https://rimuhc.ca/news-and-events"> <div class = "navitem"> <span>News and Events</span> </div> </a> </th> <th class="navitem-right"> <div class="dropdown-toggle-arrow"> <i class="fas fa-angle-down"></i> </div> </th> </tr> </table> <ul class="nav-level-2"> <li> <a href='https://rimuhc.ca/ri-muhc-live'>News</a> <ul> <li> <a href='https://rimuhc.ca/whats-new-ri-muhc'>What’s new at The Institute?</a> </li> <li> <a href='https://rimuhc.ca/research-life'>Research Life</a> </li> <li> <a href='https://rimuhc.ca/close-up'>Close-up</a> </li> <li> <a href='https://rimuhc.ca/appointments'>Appointments</a> </li> <li> <a href='https://rimuhc.ca/live-funding-results'>Funding Results</a> </li> <li> <a href='https://rimuhc.ca/honours-and-awards'>Honours and Awards</a> </li> <li> <a href='https://rimuhc.ca/trainee-kudos'>Trainee Kudos</a> </li> </ul> </li> <li> <a href='https://rimuhc.ca/events'>Events</a> <ul> <li> <a href='https://rimuhc.ca/scientific-events'>Scientific Events</a> </li> <li> <a href='https://rimuhc.ca/community-events'>Community Events</a> </li> <li> <a href='https://rimuhc.ca/distinguished-professors-lecture-series'>Distinguished Professor Lecture Series</a> </li> </ul> </li> <li> <a href='https://rimuhc.ca/news-and-events/in-memoriam'>In Memoriam</a> </li> </ul> </div> <div class="nav-level-1"> <table> <tr> <th class="navitem-left"> <a href="https://rimuhc.ca/services"> <div class = "navitem"> <span>Services</span> </div> </a> </th> <th 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portlet-boundary_com_liferay_asset_publisher_web_portlet_AssetPublisherPortlet_ portlet-static portlet-static-end portlet-barebone portlet-asset-publisher " id="p_p_id_com_liferay_asset_publisher_web_portlet_AssetPublisherPortlet_INSTANCE_AN78yFPG5ThE_"> <span id="p_com_liferay_asset_publisher_web_portlet_AssetPublisherPortlet_INSTANCE_AN78yFPG5ThE"></span> <section class="portlet" id="portlet_com_liferay_asset_publisher_web_portlet_AssetPublisherPortlet_INSTANCE_AN78yFPG5ThE"> <div class="portlet-content"> <div class=" portlet-content-container"> <div class="portlet-body"> <div class="asset-full-content clearfix mb-5 default-asset-publisher show-asset-title " data-fragments-editor-item-id="10108-17418172" data-fragments-editor-item-type="fragments-editor-mapped-item" > <div class="mb-2"> <h4 class="component-title"> <span class="header-back-to" > <a href="javascript:;" target="_self" class=" lfr-icon-item taglib-icon" id="_com_liferay_asset_publisher_web_portlet_AssetPublisherPortlet_INSTANCE_AN78yFPG5ThE_rjus__column3__0" onClick="event.preventDefault();submitForm(document.hrefFm, 'https\x3a\x2f\x2frimuhc\x2eca\x2fcontent\x2f-\x2fasset_publisher\x2fAN78yFPG5ThE\x2f')" data-senna-off="true" > <span id="qfkd__column3__0"><svg aria-hidden="true" class="lexicon-icon lexicon-icon-angle-left" focusable="false" ><use data-href="https://rimuhc.ca/o/ri-muhctheme73-theme/images/lexicon/icons.svg#angle-left"></use></svg></span> <span class="taglib-text hide-accessible">null</span> </a> </span> <span class="asset-title d-inline"> Discovery of new genes for molar pregnancies sheds light on their increased incidence in women aged 35 and over </span> <span class="d-inline-flex"> </span> </h4> </div> <span class="asset-anchor lfr-asset-anchor" id="17418178"></span> <div class="asset-content mb-3"> <div class="journal-content-article " data-analytics-asset-id="17418170" data-analytics-asset-title="Discovery of new genes for molar pregnancies sheds light on their increased incidence in women aged 35 and over" data-analytics-asset-type="web-content"> <div class="ri-modal-shade"></div> <div class="ri-modal-container"> <div class="ri-modal-content"> <div class = "ri-img-wrapper"> <img src=""> </div> <div class="ri-modal-close"> <i class="fas fa-circle" ></i> <i class="fas fa-times-circle"></i> </div> </div> </div> <div class="ri-article"> <p class="ri-article-blurb"><strong>Major advances made at the RI-MUHC could help improve counselling for individuals suffering from infertility, premature ovarian insufficiency, recurrent miscarriages and androgenetic hydatidiform mole.</strong></p><p class="ri-article-blurb"><strong>Montreal, November 18, 2024 —</strong> A molar pregnancy, also known as a hydatidiform mole, is an abnormal human pregnancy with no embryo and an overgrowth of the cells that form the placenta. The common form of molar pregnancies affects one in every 600 pregnancies in Quebec. Half of these moles are androgenetic, that is, they contain only the father’s chromosomes with no chromosomes from the mother, and their frequency increases 10 times with advanced maternal age. Because of the hyperproliferation of their cells, androgenetic moles may become malignant and lead to a placental cancer in up to 15 per cent of cases.</p><p class="ri-article-blurb">Scientists at the Research Institute of the McGill University Health Centre (RI-MUHC) recently discovered six new genes – <em>FOXL2, MAJIN, KASH5, SYCP2, HFM1 </em>and<em> MEIOB</em> – that cause recurrent androgenetic moles, recurrent miscarriages and infertility when mutated on both alleles (copies of the same gene) in the patients. Five of these genes are essential for Meiosis I, the process of cell division necessary for the production of sperm and eggs in humans. Previous studies have linked defects in some of the six genes to premature ovarian failure, a well-known cause of female infertility. In addition, five of these genes have been linked to male infertility.</p><figure class="blurb-img-full-width" style="margin: 0 auto;"><img alt="Teruko Taketo and Rima Slim, co-senior authors of the study, showing live imaging of meiotic progression in mouse oocytes." title="Teruko Taketo and Rima Slim, co-senior authors of the study, showing live imaging of meiotic progression in mouse oocytes." src="/documents/10803/17370954/discovery-new+genes-molar-pregnancies-01.jpg/40692582-ccba-992e-2ab9-803d3d6cd842?t=1731946483841" /><figcaption>Teruko Taketo and Rima Slim, co-senior authors of the study, showing live imaging of meiotic progression in mouse oocytes.</figcaption></figure><p class="ri-article-blurb">These findings, just published in <a target="_blank" href="https://www.jci.org/articles/view/170669"><em>The Journal of Clinical Investigation</em></a>, will improve the molecular diagnosis of recurrent molar pregnancies, premature ovarian failure and infertile women and men.</p><p class="ri-article-blurb">“Our findings suggest that recurrent androgenetic moles are a sign of ovarian ageing. They will change current clinical practice by introducing the evaluation of ovarian reserve for patients with recurrent moles,” says <a target="_self" href="/-/rima-slim-phd">Rima Slim, PhD</a>, corresponding and co-senior author of the study, Senior Scientist in the <a target="_self" href="/child-health-and-human-development-program">Child Health and Human Development Program</a> (CHHD) at the RI-MUHC and Professor in the Department of Human Genetics at McGill University.</p><p class="ri-article-blurb">The six new genes add to four other genes that are also responsible for recurrent molar pregnancies and that were previously discovered by the same team (<em>NLRP7</em>, discovered in 2006, and <em>MEI1, TOP6BL</em> and <em>REC114</em>, <a target="_blank" href="https://www.sciencedirect.com/science/article/pii/S0002929718303598?dgcid=author">discovered in 2018</a>).</p><p class="ri-article-blurb"><strong>A broad international investigation</strong></p><p class="ri-article-blurb">In collaboration with the team led by <a target="_self" href="/-/jacek-majewski-phd">Jacek Majewski, PhD</a>, Investigator at the RI-MUHC and Professor of Human Genetics at McGill, the researchers performed exome sequencing on 75 unrelated patients referred by physicians from around the world. These patients had at least two hydatidiform moles and did not have mutations in the previously described genes associated with the condition.</p><p class="ri-article-blurb">The researchers then checked whether the patients who were negative for biallelic mutations (on both alleles of a gene), had only one defective allele in genes with roles in Meiosis I and ovarian functions. They added 240 patients with other forms of reproductive failure - referred primarily from the MUHC Repeated Pregnancy Loss clinic, founded by Dr. William Buckett, and the Réseau des Maladies Trophoblastiques du Québec, founded by Dr. Philippe Sauthier. This second group of patients had either a molar pregnancy and at least one miscarriage, or at least two miscarriages without a molar pregnancy.</p><p class="ri-article-blurb">They found that 14 per cent to 28 per cent of these patients had one defective allele that appeared to be most frequent in patients with at least two molar pregnancies.</p><p class="ri-article-blurb">“Our data suggest that these monoallelic variants could be contributing, with other factors, to the genetic susceptibility of these patients for reproductive failure. Our study provides an explanation of the increased frequency of androgenetic moles with advanced maternal age,” explains Prof. Slim.</p><p class="ri-article-blurb">The authors of the study explain that “patients with monoallelic variants in these genes can conceive and have healthy children; however, they are at higher risk for infertility, premature ovarian insufficiency and reproductive loss than women from the general population.”</p><p class="ri-article-blurb"><strong>Modelling the genesis of moles</strong></p><p class="ri-article-blurb">To better elucidate the mechanisms underlying this health and reproductive problem, the researchers modelled the disease in mice with deficiency in the <em>HFM1</em> gene.</p><p class="ri-article-blurb">“We observed several defects that affect the meiotic progression, some of which were previously observed by our team in mice with deficiency in the Mei1 gene, another gene responsible for the causation of recurrent androgenetic moles,” explains <a target="_self" href="/-/teruko-taketo-phd">Teruko Taketo, PhD</a>, co-senior author of the study, Senior Scientist in the CHHD Program at the RI-MUHC and Professor in the Department of Surgery at McGill University. “In this study, using live-cell imaging, we were able to visualize and understand for the first time how the eggs from <em>Hfm1</em> deficient mice lose all their chromosomes.”</p><p class="ri-article-blurb">The authors emphasize that the identification of the same mechanism in two mouse models supports its plausibility at the origin of androgenetic mole formation in humans.</p><p class="ri-article-blurb">“Androgenetic moles have been described in 1977. Today, we can better explain to the patients the formation of these aberrant conceptions and the genesis of androgenetic moles,” says Prof. Slim.</p><p class="ri-article-blurb"><strong>About the study</strong></p><p class="ri-article-blurb">The study <em>Defects in meiosis I contribute to the genesis of androgenetic hydatidiform moles</em> was conducted by Maryam Rezaei, Manqi Liang, Zeynep Yalcin, Jacinta H. Martin, Parinaz Kazemi, Eric Bareke, Zhao-Jia Ge, Majid Fardaei, Claudio Benadiva, Reda Hemida, Adnan Hassan, Geoffrey J. Maher, Ebtesam Abdalla, William Buckett, Pierre-Adrien Bolze, Iqbaljit Sandhu, Onur Duman, Suraksha Agrawal, JianHua Qian, Jalal Vallian Broojeni, Lavi Bhati, Pierre Miron, Fabienne Allias, Amal Selim, Rosemary A. Fisher, Michael J. Seckl, Philippe Sauthier, Isabelle Touitou, Seang Lin Tan, Jacek Majewski, Teruko Taketo and Rima Slim.</p><p class="ri-article-blurb"><a target="_blank" href="https://doi.org/10.1172/JCI170669">DOI : https://doi.org/10.1172/JCI170669</a></p><p class="ri-article-blurb">This work was primarily supported by the Canadian Institutes of Health Research and also benefited from funding from Mitacs Accelerate in partnership with Originelle Inc., McGill’s Centre for Research in Reproduction and Development, the RI-MUHC Desjardins Studentship and the Faculty of Medicine and Health Sciences of McGill University.</p><p class="ri-article-blurb">The investigators would like to thank all the researchers and clinicians who contributed to the study, as well as the patients and families who participated.</p><figure class="blurb-img-full-width" style="margin: 0 auto;"><img alt="Study team members identified by initials" title="Study team members identified by initials" src="/documents/10803/17370954/discovery-new+genes-molar-pregnancies-02.png/cc4ee8c0-7077-bd4f-a98a-ac02c35e9781?t=1731948679252" /><figcaption>Study team members identified by initials</figcaption></figure><p class="ri-article-blurb"><strong>About the Research Institute of the McGill University Health Centre</strong></p><p class="ri-article-blurb">The Research Institute of the McGill University Health Centre (RI-MUHC) is a world-renowned biomedical and healthcare research centre. The Institute, which is affiliated with the Faculty of Medicine of McGill University, is the research arm of the McGill University Health Centre (MUHC)–an academic health centre located in Montreal, Canada, that has a mandate to focus on complex care within its community. The RI-MUHC supports over 720 researchers and close to 1,400 research trainees devoted to a broad spectrum of fundamental, clinical and health outcomes research at the Glen and the Montreal General Hospital sites of the MUHC. Its research facilities offer a dynamic multidisciplinary environment that fosters collaboration and leverages discovery aimed at improving the health of individual patients across their lifespan. The RI-MUHC is supported in part by the Fonds de recherche du Québec–Santé (FRQS). <a target="_self" href="https://rimuhc.ca">www.rimuhc.ca</a></p><p class="ri-article-blurb"><strong>Media contact</strong></p><p class="ri-article-blurb">Fabienne Landry<br />Communications coordinator, Research, MUHC<br />Fabienne<span style="display: none;" aria-hidden="true">Praesent id dolor porta, faucibus eros vel</span>.landry@muhc.mcgill.ca</p><p class="ri-article-blurb"><br /><strong>Related news</strong></p><p class="ri-article-blurb"><a target="_self" href="/-/recurrent-miscarriage-what-if-the-cause-is-genetic">Recurrent miscarriage: what if the cause is genetic?</a></p> </div> <style> /*The styling for .cell and cell-shrink were added as per Communications (for the 'Distinguished Professors Lecture series') and is meant as a work-around, temporary solution, applied only to that table.*/ .ri-table-row .cell { width: 65%; } .ri-table-row .cell-shrink { width: 100%; padding-left: 15px; } @media (max-width: 767px){ .ri-table-row.header { visibility: hidden; 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Discovery of new genes for molar pregnancies sheds light on their increased incidence in women aged 35 and over - Research Institute of the McGill University Health Centre - RI-MUHC