Nona Biosciences | LinkedIn

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Empower Global Biotherapeutic Innovation | Nona Biosciences is a global biotechnology company committed to providing a total solution for partners worldwide, from academies, biotech startups to biopharma giants. The integrated antibody discovery services range from antigen preparation, animal immunization, single B cell screening, to antibody lead generation and engineering, developability assessment and pharmacological evaluation, leveraging the advantages of Harbour Mice® platforms and the experienced therapeutic antibody discovery team. Harbour Mice® generates fully human monoclonal antibodies in two heavy and two light chains (H2L2) format, as well as heavy chain only (HCAb) format."> <meta property="og:title" content="Nona Biosciences | LinkedIn"> <meta property="og:description" content="Nona Biosciences | 5,629 followers on LinkedIn. Empower Global Biotherapeutic Innovation | Nona Biosciences is a global biotechnology company committed to providing a total solution for partners worldwide, from academies, biotech startups to biopharma giants. The integrated antibody discovery services range from antigen preparation, animal immunization, single B cell screening, to antibody lead generation and engineering, developability assessment and pharmacological evaluation, leveraging the advantages of Harbour Mice® platforms and the experienced therapeutic antibody discovery team. Harbour Mice® generates fully human monoclonal antibodies in two heavy and two light chains (H2L2) format, as well as heavy chain only (HCAb) format."> <meta property="og:image" content="https://media.licdn.com/dms/image/v2/C560BAQE1Hvk5CZp_oQ/company-logo_200_200/company-logo_200_200/0/1668124699478?e=2147483647&v=beta&t=ABdDkAfbYKvnOMECeo3ubSt3g5mRwz-OeCHiLtFRfds"> <meta property="og:type" content="article"> <meta property="og:url" content="https://www.linkedin.com/company/nonabiosciences"> <meta name="twitter:card" content="summary"> <meta name="twitter:site" content="@linkedin"> <meta name="twitter:title" content="Nona Biosciences | LinkedIn"> <meta name="twitter:description" content="Nona Biosciences | 5,629 followers on LinkedIn. Empower Global Biotherapeutic Innovation | Nona Biosciences is a global biotechnology company committed to providing a total solution for partners worldwide, from academies, biotech startups to biopharma giants. The integrated antibody discovery services range from antigen preparation, animal immunization, single B cell screening, to antibody lead generation and engineering, developability assessment and pharmacological evaluation, leveraging the advantages of Harbour Mice® platforms and the experienced therapeutic antibody discovery team. Harbour Mice® generates fully human monoclonal antibodies in two heavy and two light chains (H2L2) format, as well as heavy chain only (HCAb) format."> <meta name="twitter:image" content="https://media.licdn.com/dms/image/v2/C560BAQE1Hvk5CZp_oQ/company-logo_200_200/company-logo_200_200/0/1668124699478?e=2147483647&v=beta&t=ABdDkAfbYKvnOMECeo3ubSt3g5mRwz-OeCHiLtFRfds"> <meta name="clientSideIngraphs" content="1" data-gauge-metric-endpoint="/organization-guest/api/ingraphs/gauge" data-counter-metric-endpoint="/organization-guest/api/ingraphs/counter"> <link rel="stylesheet" href="https://static.licdn.com/aero-v1/sc/h/7w6w374587hrap8eiqkfaizgr"> <script type="application/ld+json"> {"@context":"http://schema.org","@type":"Organization","name":"Nona Biosciences","url":"https://www.linkedin.com/company/nonabiosciences","address":{"type":"PostalAddress","streetAddress":"1 Broadway","addressLocality":"Cambridge","addressRegion":"Massachusetts","postalCode":"02142","addressCountry":"US"},"description":"Nona Biosciences is a global biotechnology company committed to providing a total solution for partners worldwide, from academies, biotech startups to biopharma giants. The integrated antibody discovery services range from antigen preparation, animal immunization, single B cell screening, to antibody lead generation and engineering, developability assessment and pharmacological evaluation, leveraging the advantages of Harbour Mice® platforms and the experienced therapeutic antibody discovery team. \nHarbour Mice® generates fully human monoclonal antibodies in two heavy and two light chains (H2L2) format, as well as heavy chain only (HCAb) format. Integrating Harbour Mice® and a single B cell cloning platform, Nona Biosciences is focused on driving global inventions of transformative next-generation drugs by diversified partnership strategies including co-discovery, platform and antibody discovery, and platform license. The values of the antibody discovery platforms and flexible partnership models have been well validated by more than 50 industry and academic partners within over 200 projects.","numberOfEmployees":{"value":35,"@type":"QuantitativeValue"},"logo":{"contentUrl":"https://media.licdn.com/dms/image/v2/C560BAQE1Hvk5CZp_oQ/company-logo_200_200/company-logo_200_200/0/1668124699478?e=2147483647&v=beta&t=ABdDkAfbYKvnOMECeo3ubSt3g5mRwz-OeCHiLtFRfds","description":"Nona Biosciences","@type":"ImageObject"},"slogan":"Empower Global Biotherapeutic Innovation","sameAs":"https://www.nonabio.com/"} </script>  </head> <body dir="ltr">   <a href="#main-content" class="skip-link btn-md btn-primary absolute z-11 -top-[100vh] focus:top-0"> Skip to main content </a> <header class="header base-detail-page__header px-mobile-container-padding bg-color-background-container global-alert-offset"> <nav class="nav pt-1.5 pb-2 flex items-center justify-between relative flex-nowrap babymamabear:py-1.5 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class="core-section-container__content break-words"> <p class="break-words whitespace-pre-wrap text-color-text" data-test-id="about-us__description">Nona Biosciences is a global biotechnology company committed to providing a total solution for partners worldwide, from academies, biotech startups to biopharma giants. The integrated antibody discovery services range from antigen preparation, animal immunization, single B cell screening, to antibody lead generation and engineering, developability assessment and pharmacological evaluation, leveraging the advantages of Harbour Mice® platforms and the experienced therapeutic antibody discovery team. Harbour Mice® generates fully human monoclonal antibodies in two heavy and two light chains (H2L2) format, as well as heavy chain only (HCAb) format. Integrating Harbour Mice® and a single B cell cloning platform, Nona Biosciences is focused on driving global inventions of transformative next-generation drugs by diversified partnership strategies including co-discovery, platform and antibody discovery, and platform license. The values of the antibody discovery platforms and flexible partnership models have been well validated by more than 50 industry and academic partners within over 200 projects.</p> <dl class="mt-6"> <div class="mb-2 flex papabear:mr-3 mamabear:mr-3 babybear:flex-wrap" data-test-id="about-us__website"> <dt class="font-sans text-md font-bold text-color-text break-words w-40 papabear:flex-shrink-0 papabear:mr-3 mamabear:flex-shrink-0 mamabear:mr-3 babybear:mb-1"> Website </dt> <dd class="font-sans text-md text-color-text break-words overflow-hidden"> <a class="link-no-visited-state hover:no-underline" data-tracking-control-name="about_website" href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Fwww%2Enonabio%2Ecom%2F&urlhash=fYe6&trk=about_website" target="_blank" rel="noopener" data-tracking-will-navigate aria-describedby="websiteLinkDescription"> https://www.nonabio.com/ <icon class="align-middle" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/49229g4q0jsla5l1xojq1wob9" aria-hidden="true"></icon> </a> <p class="hidden" id="websiteLinkDescription">External link for Nona Biosciences</p> </dd> </div> <div class="mb-2 flex papabear:mr-3 mamabear:mr-3 babybear:flex-wrap" data-test-id="about-us__industry"> <dt class="font-sans text-md font-bold text-color-text break-words w-40 papabear:flex-shrink-0 papabear:mr-3 mamabear:flex-shrink-0 mamabear:mr-3 babybear:mb-1"> Industry </dt> <dd class="font-sans text-md text-color-text break-words overflow-hidden"> Biotechnology Research </dd> </div> <div class="mb-2 flex papabear:mr-3 mamabear:mr-3 babybear:flex-wrap" data-test-id="about-us__size"> <dt class="font-sans text-md font-bold text-color-text break-words w-40 papabear:flex-shrink-0 papabear:mr-3 mamabear:flex-shrink-0 mamabear:mr-3 babybear:mb-1"> Company size </dt> <dd class="font-sans text-md text-color-text break-words overflow-hidden"> 51-200 employees </dd> </div> <div class="mb-2 flex papabear:mr-3 mamabear:mr-3 babybear:flex-wrap" data-test-id="about-us__headquarters"> <dt class="font-sans text-md font-bold text-color-text break-words w-40 papabear:flex-shrink-0 papabear:mr-3 mamabear:flex-shrink-0 mamabear:mr-3 babybear:mb-1"> Headquarters </dt> <dd class="font-sans text-md text-color-text break-words overflow-hidden"> Cambridge, Massachusetts </dd> </div> <div class="mb-2 flex papabear:mr-3 mamabear:mr-3 babybear:flex-wrap" data-test-id="about-us__organizationType"> <dt class="font-sans text-md font-bold text-color-text break-words w-40 papabear:flex-shrink-0 papabear:mr-3 mamabear:flex-shrink-0 mamabear:mr-3 babybear:mb-1"> Type </dt> <dd class="font-sans text-md text-color-text break-words overflow-hidden"> Public Company </dd> </div> <div class="mb-2 flex papabear:mr-3 mamabear:mr-3 babybear:flex-wrap" data-test-id="about-us__foundedOn"> <dt class="font-sans text-md font-bold text-color-text break-words w-40 papabear:flex-shrink-0 papabear:mr-3 mamabear:flex-shrink-0 mamabear:mr-3 babybear:mb-1"> Founded </dt> <dd class="font-sans text-md text-color-text break-words overflow-hidden"> 2022 </dd> </div>  </dl> </div> </section>  <section class="core-section-container core-section-container--with-border border-b-1 border-solid border-color-border-faint py-4 locations">  <h2 class="core-section-container__title section-title"> Locations </h2>  <div class="core-section-container__content break-words"> <ul class="show-more-less__list show-more-less__list--no-hidden-elems" data-impression-id="org-locations_show-more-less"> <li class="mb-3 papabear:w-50% papabear:odd:mr-2 papabear:odd:w-[calc(50%-16px)]"> <span class="tag-sm tag-enabled"> Primary </span> <div id="address-0"> <p> 1 Broadway </p>  <p> Cambridge, Massachusetts 02142, US </p> </div> <a class="link-no-visited-state hover:no-underline" data-tracking-control-name="org-locations_url" href="https://www.bing.com/maps?where=1+Broadway+Cambridge+02142+Massachusetts+US&trk=org-locations_url" target="_blank" rel="noopener" data-tracking-will-navigate aria-describedby="address-0"> Get directions <icon class="align-middle" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/49229g4q0jsla5l1xojq1wob9" aria-hidden="true"></icon> </a> </li> </ul> </div> </section> <section class="core-section-container core-section-container--with-border border-b-1 border-solid border-color-border-faint py-4" data-test-id="employees-at">  <h2 class="core-section-container__title section-title"> Employees at Nona Biosciences </h2>  <div class="core-section-container__content break-words"> <ul> <li> <a href="https://www.linkedin.com/in/imranclark?trk=org-employees" target="_self" data-tracking-control-name="org-employees" data-tracking-will-navigate class="base-card relative w-full hover:no-underline focus:no-underline base-card--link base-main-card flex flex-wrap py-2 pr-2 babybear:pr-0 base-main-card--link ">  <img class="inline-block relative rounded-[50%] w-6 h-6 " data-delayed-url="https://media.licdn.com/dms/image/v2/C5603AQFnNjhMDCDNuQ/profile-displayphoto-shrink_100_100/profile-displayphoto-shrink_100_100/0/1647034136259?e=2147483647&v=beta&t=zvV-5uN4OCSOdE9PhjgRWtJaqspCnk4loOVY_1a5RWc" data-ghost-classes="bg-color-entity-ghost-background" data-ghost-url="https://static.licdn.com/aero-v1/sc/h/9c8pery4andzj6ohjkjp54ma2" alt="Click here to view Imran Clark, PhD’s profile"> <div class="base-main-card__info self-center ml-1 flex-1 relative break-words papabear:min-w-0 mamabear:min-w-0 babybear:w-full ">  <h3 class="base-main-card__title font-sans text-[18px] font-bold text-color-text overflow-hidden "> Imran Clark, PhD  </h3> <h4 class="base-main-card__subtitle body-text text-color-text overflow-hidden "> Business Development/Product Development/Project Management/Quality in Biotech/Pharma </h4>   </div>  </a> </li> <li> <a href="https://www.linkedin.com/in/jingsong-wang-3b003a3?trk=org-employees" target="_self" data-tracking-control-name="org-employees" data-tracking-will-navigate class="base-card relative w-full hover:no-underline focus:no-underline base-card--link base-main-card flex flex-wrap py-2 pr-2 babybear:pr-0 base-main-card--link ">  <img class="inline-block relative rounded-[50%] w-6 h-6 " data-delayed-url="https://media.licdn.com/dms/image/v2/C4E03AQGbZyMEhVWtCQ/profile-displayphoto-shrink_100_100/profile-displayphoto-shrink_100_100/0/1516284443967?e=2147483647&v=beta&t=7_2Fb2c77Z-gylIDrjka7lV1dnT2BUNNflMv6n3Ampk" data-ghost-classes="bg-color-entity-ghost-background" data-ghost-url="https://static.licdn.com/aero-v1/sc/h/9c8pery4andzj6ohjkjp54ma2" alt="Click here to view Jingsong Wang’s profile"> <div class="base-main-card__info self-center ml-1 flex-1 relative break-words papabear:min-w-0 mamabear:min-w-0 babybear:w-full ">  <h3 class="base-main-card__title font-sans text-[18px] font-bold text-color-text overflow-hidden "> Jingsong Wang  </h3>    </div>  </a> </li> <li> <a href="https://nl.linkedin.com/in/xiangyu-rao-phd-mba-86788a14?trk=org-employees" target="_self" data-tracking-control-name="org-employees" data-tracking-will-navigate class="base-card relative w-full hover:no-underline focus:no-underline base-card--link base-main-card flex flex-wrap py-2 pr-2 babybear:pr-0 base-main-card--link ">  <img class="inline-block relative rounded-[50%] w-6 h-6 " data-delayed-url="https://media.licdn.com/dms/image/v2/D4E03AQFgrLqxcVVKgA/profile-displayphoto-shrink_100_100/profile-displayphoto-shrink_100_100/0/1716390081817?e=2147483647&v=beta&t=n2ievMriXfd0y6VLG3pSVsFeoJwLiSdmF7c_TS8Ixjo" data-ghost-classes="bg-color-entity-ghost-background" data-ghost-url="https://static.licdn.com/aero-v1/sc/h/9c8pery4andzj6ohjkjp54ma2" alt="Click here to view Xiangyu Rao, PHD, MBA’s profile"> <div class="base-main-card__info self-center ml-1 flex-1 relative break-words papabear:min-w-0 mamabear:min-w-0 babybear:w-full ">  <h3 class="base-main-card__title font-sans text-[18px] font-bold text-color-text overflow-hidden "> Xiangyu Rao, PHD, MBA  </h3> <h4 class="base-main-card__subtitle body-text text-color-text overflow-hidden "> Business Development @ Nona Biosciences | Executive MBA </h4>   </div>  </a> </li> <li> <a href="https://cn.linkedin.com/in/junwu5755?trk=org-employees" target="_self" data-tracking-control-name="org-employees" data-tracking-will-navigate class="base-card relative w-full hover:no-underline focus:no-underline base-card--link base-main-card flex flex-wrap py-2 pr-2 babybear:pr-0 base-main-card--link ">  <img class="inline-block relative rounded-[50%] w-6 h-6 " data-delayed-url="https://media.licdn.com/dms/image/v2/C5603AQGLjivpAAHebw/profile-displayphoto-shrink_100_100/profile-displayphoto-shrink_100_100/0/1568194999349?e=2147483647&v=beta&t=y4YSNOaP8Hoa-UpeaVCF_AafEX1tHDTvtgREAHgz5_o" data-ghost-classes="bg-color-entity-ghost-background" data-ghost-url="https://static.licdn.com/aero-v1/sc/h/9c8pery4andzj6ohjkjp54ma2" alt="Click here to view Jun Wu’s profile"> <div class="base-main-card__info self-center ml-1 flex-1 relative break-words papabear:min-w-0 mamabear:min-w-0 babybear:w-full ">  <h3 class="base-main-card__title font-sans text-[18px] font-bold text-color-text overflow-hidden "> Jun Wu  </h3> <h4 class="base-main-card__subtitle body-text text-color-text overflow-hidden "> Scientist developing innovative medicine </h4>   </div>  </a> </li> </ul> <a class="mt-4 inline-block btn-md btn-secondary-emphasis hover:no-underline" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww%2Elinkedin%2Ecom%2Fsearch%2Fresults%2Fpeople%2F%3FfacetCurrentCompany%3D%255B89792629%255D&trk=public_biz_employees-join" data-tracking-control-name="public_biz_employees-join" data-tracking-will-navigate> See all employees </a> </div> </section> <section class="core-section-container core-section-container--with-border border-b-1 border-solid border-color-border-faint py-4 updates" data-test-id="updates">  <h2 class="core-section-container__title section-title"> Updates </h2>  <div class="core-section-container__content break-words"> <ul class="updates__list"> <li class="mb-1"> <div data-id="entire-feed-card-link" class="relative"> <a class="main-feed-card__overlay-link absolute left-0 top-0 h-full w-full z-1 !border-0" href="https://www.linkedin.com/posts/nonabiosciences_advanced-custom-linkers-adc-development-activity-7265038663087009794-i67h" data-id="main-feed-card__full-link" data-tracking-control-name="organization_guest_main-feed-card__full-link" data-tracking-will-navigate aria-label="Update 1"> </a> <article class="relative pt-1.5 px-2 pb-0 bg-color-background-container container-lined main-feed-activity-card papabear:max-w-[550px]" data-activity-urn="urn:li:activity:7265038663087009794" data-featured-activity-urn="urn:li:activity:7265038663087009794" data-attributed-urn="urn:li:ugcPost:7265038662134910977" data-id="main-feed-card">   <div class="flex items-center font-sans mb-1" data-test-id="main-feed-activity-card__entity-lockup"> <a href="https://www.linkedin.com/company/nonabiosciences?trk=organization_guest_main-feed-card_feed-actor-image" class="relative" data-tracking-control-name="organization_guest_main-feed-card_feed-actor-image" data-tracking-will-navigate> <img class="inline-block relative w-6 h-6 " data-delayed-url="https://media.licdn.com/dms/image/v2/C560BAQE1Hvk5CZp_oQ/company-logo_100_100/company-logo_100_100/0/1668124699478?e=2147483647&v=beta&t=Sk53JfHpPQ5z_f2fC2oBdXlKsXGMzomZ0XhWikfJ-PU" data-ghost-classes="bg-color-entity-ghost-background" data-ghost-url="https://static.licdn.com/aero-v1/sc/h/cs8pjfgyw96g44ln9r7tct85f" alt="View organization page for Nona Biosciences, graphic">  </a> <div class="flex flex-col self-start min-w-0 ml-1 "> <div class="text-color-text "> <a class="text-sm link-styled no-underline leading-open" href="https://www.linkedin.com/company/nonabiosciences?trk=organization_guest_main-feed-card_feed-actor-name" data-tracking-control-name="organization_guest_main-feed-card_feed-actor-name" aria-label="View organization page for Nona Biosciences" data-tracking-will-navigate> Nona Biosciences </a>  </div> <p class="!text-xs text-color-text-low-emphasis leading-[1.33333] m-0 truncate">  5,629 followers </p> <span class="!text-xs text-color-text-low-emphasis leading-[1.33333] flex"> <time class="flex-none"> 2d <span aria-hidden="true" class="text-color-text-low-emphasis before:middot"></span> <span> Edited </span> </time>  </span> </div>  </div> <div class="ellipsis-menu absolute right-0 top-0 !mr-0.5" data-test-id="main-feed-activity-card__ellipsis-menu"> <div class="collapsible-dropdown flex items-center relative hyphens-auto"> <button class="ellipsis-menu__trigger collapsible-dropdown__button btn-md btn-tertiary cursor-pointer !py-[6px] !px-1 flex items-center 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class="attributed-text-segment-list__content text-color-text !text-sm whitespace-pre-wrap break-words " dir="ltr" data-test-id="main-feed-activity-card__commentary">𝗗𝗲𝘃𝗲𝗹𝗼𝗽𝗶𝗻𝗴 𝗔𝗗𝗖𝘀? 𝗛𝗲𝗿𝗲 𝗮𝗿𝗲 𝘀𝗼𝗺𝗲 𝗼𝗳 𝘁𝗵𝗲 𝘁𝗼𝘂𝗴𝗵𝗲𝘀𝘁 𝗰𝗵𝗮𝗹𝗹𝗲𝗻𝗴𝗲𝘀: - 𝗧𝘂𝗺𝗼𝗿 𝗛𝗲𝘁𝗲𝗿𝗼𝗴𝗲𝗻𝗲𝗶𝘁𝘆: Varying antigen expression across tumor cells can lead to inconsistent results. - 𝗜𝗻𝘁𝗲𝗿𝗻𝗮𝗹𝗶𝘇𝗮𝘁𝗶𝗼𝗻 𝗘𝗳𝗳𝗶𝗰𝗶𝗲𝗻𝗰𝘆: ADCs must penetrate cells and release payloads effectively within the tumor microenvironment. - 𝗥𝗲𝘀𝗶𝘀𝘁𝗮𝗻𝗰𝗲 𝗠𝗲𝗰𝗵𝗮𝗻𝗶𝘀𝗺𝘀: Tumor cells can block ADCs, impacting efficacy and limiting therapeutic potential. Nona Biosciences develops internalization-independent custom linkers with high stability, precise release, and payload compatibility, designed specifically for complex tumor environments. Reach out to explore how we can enhance your ADC pipeline! <a class="link" href="https://lnkd.in/eyHStt4y?trk=organization_guest_main-feed-card-text" target="_self" rel="nofollow" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>https://lnkd.in/eyHStt4y</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fadc&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#ADC</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fantibodies&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#antibodies</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fdrugdevelopment&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#drugdevelopment</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fantibodydiscovery&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#antibodydiscovery</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fhcab&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#HCAb</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fheavychainantibodies&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#heavychainantibodies</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Ffullyhuman&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#FullyHuman</a></p>  </div> <iframe class="h-[293px] w-main-feed-card-media" allowfullscreen frameborder="0" data-id="feed-paginated-document-content" data-delayed-url="https://media.licdn.com/embeds/native-document.html" data-native-document-config="{"action":"init","a11y":{"pagination":{"paginationValue":"Current page","paginationLength":"Total pages"},"sidepanelLeft":{"navButton":"Go to previous page of document"},"sidepanelRight":{"navButton":"Go to next page of document"},"topbar":{"cancelButton":"Exit full screen","downloadButton":"Download document"},"toolbarA11y":{"fullscreenOnButtonA11yControlText":"Enter full screen. 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data-tracking-will-navigate data-item-type="semaphore" data-semaphore-content-type="POST" data-semaphore-content-urn="urn:li:activity:7264671822577549314" data-semaphore-tracking-prefix="organization_guest_main-feed-card_ellipsis-menu-semaphore" data-is-logged-in="false" data-modal="semaphore__toggle" class="semaphore__toggle visited:text-color-text-secondary ellipsis-menu__semaphore ellipsis-menu__item-button flex items-center w-full p-1 cursor-pointer font-sans text-sm font-bold link-styled focus:link-styled link:no-underline active:bg-color-background-container-tint focus:bg-color-background-container-tint hover:bg-color-background-container-tint outline-offset-[-2px]">  <icon class="ellipsis-menu__item-icon text-color-text h-[24px] w-[24px] mr-1" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/iq0x9q37wj214o129ai1yjut"> </icon> Report this post </a>  </li>  </ul>  </div> </div> <div class="attributed-text-segment-list__container relative mt-1 mb-1.5 babybear:mt-0 babybear:mb-0.5"> <p class="attributed-text-segment-list__content text-color-text !text-sm whitespace-pre-wrap break-words " dir="ltr" data-test-id="main-feed-activity-card__commentary">A Breakthrough in Medicine: Fully Human HCAb-Based mRNA-LNP 🧬 mRNA-encoding biologics are changing the game in modern medicine! At Nona Biosciences, we’re harnessing cutting-edge mRNA technology to bring the future of therapeutics to life. Here's how our fully human HCAb-based mRNA-LNP platform is making waves: <a class="link" href="https://nonabio.com/mrna?trk=organization_guest_main-feed-card-text" target="_self" rel="nofollow" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>https://nonabio.com/mrna</a> 🔬 What Sets Our Technology Apart? 1️⃣ Exceptional Cytotoxicity: Our HCAb TAA x CD3 mRNA-LNP exhibits remarkable cytotoxic effects on TAA-expressing target cells. 2️⃣ Specific Killing Effect: Precision matters! The TAA x CD3 mRNA-LNP targets TAA-positive cells specifically, reducing off-target risks and increasing safety. 3️⃣ Distinct Killing Pattern: This approach delivers a unique killing pattern compared to traditional methods, maximizing therapeutic potential. 4️⃣ Potent Anti-Tumor Efficacy: In vivo studies show that our mRNA-LNP therapy significantly reduces tumor volume, with efficacy scaling with dosage. With the Harbour HCAb Mice® platform at the core, our innovative solution is shaping the future of targeted, effective cancer treatments. 🌐💥 👉 Stay tuned as we continue to advance next-gen therapies! <a class="link" href="https://nonabio.com/mrna?trk=organization_guest_main-feed-card-text" target="_self" rel="nofollow" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>https://nonabio.com/mrna</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fmrna&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#mRNA</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fmrnatherapy&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#mRNATherapy</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fcancertherapy&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#CancerTherapy</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fhcab&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#HCAb</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fprecisionmedicine&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#PrecisionMedicine</a> <a class="link" 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class="attributed-text-segment-list__content text-color-text !text-sm whitespace-pre-wrap break-words " dir="ltr" data-test-id="main-feed-activity-card__commentary">🌟 Unlock the Future of CAR-T Therapy with Nona Biosciences! 🌟 Are you looking to stay at the cutting edge of cancer treatment advancements? Our latest white paper dives deep into how Nona Biosciences is transforming CAR-T therapy using state-of-the-art, fully human heavy chain antibodies (HCAbs) for superior efficacy and safety. Highlights of our innovations: - 𝗡𝗼𝗻𝗮𝗖𝗔𝗥™ 𝗧𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆: Leverages fully human HCAbs to reduce immunogenicity and maximize therapeutic impact. - 𝗡𝗼𝗻𝗮𝗖𝗮𝗿𝗙𝘅™ 𝗣𝗹𝗮𝘁𝗳𝗼𝗿𝗺: Pioneering direct CAR-function-based HCAb screening for faster, more efficient development. - 𝗕𝗲𝗮𝗰𝗼𝗻® 𝗧𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆: Achieve single-day antibody discovery, optimizing labor and throughput. - 𝗖𝗼𝗺𝗽𝗿𝗲𝗵𝗲𝗻𝘀𝗶𝘃𝗲 𝗜𝗻 𝗩𝗶𝘁𝗿𝗼 𝗖𝗵𝗮𝗿𝗮𝗰𝘁𝗲𝗿𝗶𝘇𝗮𝘁𝗶𝗼𝗻: Ensures robust, high-performance CAR-T cell therapy. Ready to explore the science behind these breakthroughs? Download the full white paper to learn more about our integrated technologies and how we're driving the future of CAR-T therapies. 👉 <a class="link" href="https://lnkd.in/eNiMxrrF?trk=organization_guest_main-feed-card-text" target="_self" rel="nofollow" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>https://lnkd.in/eNiMxrrF</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fhcab&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#HCAb</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fheavychainonly&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#heavychainonly</a> <a class="link" 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With mechanisms like ADCC, CDC, and peptide-MHC targeting, TCRm antibodies enhance tumor cell destruction. 💡They also provide antibody-like stability and a long half-life, while being easier to manufacture than traditional TCR-based therapies, making them scalable for large-scale application. Nona Biosciences is at the forefront of this innovation, advancing cancer treatment with highly specific and promising TCRm designs. 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babybear:mb-0.5"> <p class="attributed-text-segment-list__content text-color-text !text-sm whitespace-pre-wrap break-words " dir="ltr" data-test-id="main-feed-activity-card__commentary">Introducing our custom linker Solution for advanced bioconjugate therapies While off-the-shelf linkers offer convenience in ADC development, overcoming therapeutic challenges such as internalization efficiency and targeted release requires custom solutions. Nona Biosciences screens peptides based on natural substrates and tumor-associated enzyme structures to develop linkers that optimize payload release specifically within the tumor microenvironment. Contact us today to help your ADCs reach their full potential: <a class="link" href="https://lnkd.in/eyHStt4y?trk=organization_guest_main-feed-card-text" target="_self" rel="nofollow" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>https://lnkd.in/eyHStt4y</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fadc&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#ADC</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fantibodies&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#antibodies</a> <a class="link" 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graphic">  </a> <div class="flex flex-col self-start min-w-0 ml-1 "> <div class="text-color-text "> <a class="text-sm link-styled no-underline leading-open" href="https://www.linkedin.com/company/nonabiosciences?trk=organization_guest_main-feed-card_feed-actor-name" data-tracking-control-name="organization_guest_main-feed-card_feed-actor-name" aria-label="View organization page for Nona Biosciences" data-tracking-will-navigate> Nona Biosciences </a>  </div> <p class="!text-xs text-color-text-low-emphasis leading-[1.33333] m-0 truncate">  5,629 followers </p> <span class="!text-xs text-color-text-low-emphasis leading-[1.33333] flex"> <time class="flex-none"> 2w  </time>  </span> </div>  </div> <div class="ellipsis-menu absolute right-0 top-0 !mr-0.5" data-test-id="main-feed-activity-card__ellipsis-menu"> <div class="collapsible-dropdown flex items-center relative hyphens-auto"> <button class="ellipsis-menu__trigger collapsible-dropdown__button btn-md btn-tertiary cursor-pointer 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babybear:mb-0.5"> <p class="attributed-text-segment-list__content text-color-text !text-sm whitespace-pre-wrap break-words " dir="ltr" data-test-id="main-feed-activity-card__commentary">The moment is finally here! Join us at Booth #417 and then head over to the Town & Country Room D at 12:30 PM to discover our groundbreaking Novel Enzyme Cleavable Linker for the Development of Next-Gen ADCs against Solid Tumors. Whether you have just a brief moment to drop by or want to engage in deeper conversation, we're here to explore how we can help you advance your next ADC therapeutic. Looking forward to seeing you there! <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fadc&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#ADC</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fantibodies&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#antibodies</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fdrugdevelopment&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#drugdevelopment</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fantibodydiscovery&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#antibodydiscovery</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fhcab&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#HCAb</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fheavychainantibodies&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#heavychainantibodies</a></p>  </div> <ul class="grid grid-cols-6 grid-rows-[60%_40%] w-main-feed-card-media 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class="text-color-text "> <a class="text-sm link-styled no-underline leading-open" href="https://www.linkedin.com/company/nonabiosciences?trk=organization_guest_main-feed-card_feed-actor-name" data-tracking-control-name="organization_guest_main-feed-card_feed-actor-name" aria-label="View organization page for Nona Biosciences" data-tracking-will-navigate> Nona Biosciences </a>  </div> <p class="!text-xs text-color-text-low-emphasis leading-[1.33333] m-0 truncate">  5,629 followers </p> <span class="!text-xs text-color-text-low-emphasis leading-[1.33333] flex"> <time class="flex-none"> 2w  </time>  </span> </div>  </div> <div class="ellipsis-menu absolute right-0 top-0 !mr-0.5" data-test-id="main-feed-activity-card__ellipsis-menu"> <div class="collapsible-dropdown flex items-center relative hyphens-auto"> <button class="ellipsis-menu__trigger collapsible-dropdown__button btn-md btn-tertiary cursor-pointer !py-[6px] !px-1 flex items-center rounded-[50%] " aria-expanded="false" 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data-semaphore-content-type="POST" data-semaphore-content-urn="urn:li:activity:7259485538141847552" data-semaphore-tracking-prefix="organization_guest_main-feed-card_ellipsis-menu-semaphore" data-is-logged-in="false" data-modal="semaphore__toggle" class="semaphore__toggle visited:text-color-text-secondary ellipsis-menu__semaphore ellipsis-menu__item-button flex items-center w-full p-1 cursor-pointer font-sans text-sm font-bold link-styled focus:link-styled link:no-underline active:bg-color-background-container-tint focus:bg-color-background-container-tint hover:bg-color-background-container-tint outline-offset-[-2px]">  <icon class="ellipsis-menu__item-icon text-color-text h-[24px] w-[24px] mr-1" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/iq0x9q37wj214o129ai1yjut"> </icon> Report this post </a>  </li>  </ul>  </div> </div> <div class="attributed-text-segment-list__container relative mt-1 mb-1.5 babybear:mt-0 babybear:mb-0.5"> <p class="attributed-text-segment-list__content text-color-text !text-sm whitespace-pre-wrap break-words " dir="ltr" data-test-id="main-feed-activity-card__commentary">TCRm antibodies represent a breakthrough in cancer immunotherapy, combining T-cell receptor specificity with antibody properties to target a wider range of intracellular antigens. Unlike traditional therapies, TCRm antibodies offer unique advantages: - 𝗕𝗿𝗼𝗮𝗱𝗲𝗿 𝗔𝗻𝘁𝗶𝗴𝗲𝗻 𝗧𝗮𝗿𝗴𝗲𝘁𝗶𝗻𝗴: Recognize intracellular antigens presented by MHC molecules, expanding beyond surface targets. - 𝗛𝗶𝗴𝗵𝗲𝗿 𝗔𝗳𝗳𝗶𝗻𝗶𝘁𝘆: Achieve subnanomolar affinity, potentially enhancing therapeutic effectiveness. - 𝗠𝘂𝗹𝘁𝗶𝗽𝗹𝗲 𝗠𝗲𝗰𝗵𝗮𝗻𝗶𝘀𝗺𝘀 𝗼𝗳 𝗔𝗰𝘁𝗶𝗼𝗻 (𝗠𝗢𝗔): Enable tumor cell killing through ADCC, CDC, and specific peptide-MHC recognition. - 𝗔𝗻𝘁𝗶𝗯𝗼𝗱𝘆-𝗟𝗶𝗸𝗲 𝗣𝗵𝗮𝗿𝗺𝗮𝗰𝗼𝗹𝗼𝗴𝘆: Offer a long half-life and stability for sustained action. - 𝗦𝗰𝗮𝗹𝗮𝗯𝗹𝗲 𝗣𝗿𝗼𝗱𝘂𝗰𝘁𝗶𝗼𝗻: Easier to manufacture than TCR-based therapies, ideal for large-scale applications. Nona Biosciences' TCRm antibodies are leading the way with innovative design and high specificity, holding strong promise for advancing cancer treatment.💡 Learn more: <a class="link" href="https://lnkd.in/eT-_VkKp?trk=organization_guest_main-feed-card-text" target="_self" rel="nofollow" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>https://lnkd.in/eT-_VkKp</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Ftcrm&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#TCRm</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Ftcrmimic&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#TCRmimic</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fantibodies&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#antibodies</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fhcab&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#HCAb</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fcancerresearch&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#CancerResearch</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fimmunotherapy&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#Immunotherapy</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fbiotech&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#Biotech</a></p>  </div>  <a href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Fnonabio%2Ecom%2Ftcrm-antibody%2F&urlhash=E5Cq&trk=organization_guest_main-feed-card_feed-article-content" target="_self" data-tracking-control-name="organization_guest_main-feed-card_feed-article-content" data-tracking-will-navigate class="flex flex-col feed-article-content" data-test-id="article-content"> <img alt="TCR Mimic Antibody - Nona Biosciences" class="lazy-load w-main-feed-card-media object-cover babybear:max-h-[400px]" data-delayed-url="https://media.licdn.com/dms/image/sync/v2/D4E27AQF3jyyitO7Baw/articleshare-shrink_800/articleshare-shrink_800/0/1719930770335?e=2147483647&v=beta&t=MtZVJ7qxzMnQXF2Ovd6MXcB5fogHudZfd52W_J3BCUE" data-ghost-classes="tw-feed-content-ghost-image" data-ghost-url="https://static.licdn.com/aero-v1/sc/h/42byfw7gh464l64dlwodbbdez">  <section class="flex justify-between article-content__header py-1"> <header> <h2 class="tw-feed-content-title" dir="ltr" data-test-id="article-content__title"> TCR Mimic Antibody - Nona Biosciences </h2> <h3 class="tw-feed-content-subtitle" data-test-id="article-content__subtitle"> https://nonabio.com </h3> </header>  </section> </a>   <code id="i18n_reaction_singular" style="display: none"></code> <code id="i18n_reactions_plural" style="display: none"></code> <div class="flex items-center font-sans text-sm babybear:text-xs 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aria-label="Update 8"> </a> <article class="relative pt-1.5 px-2 pb-0 bg-color-background-container container-lined main-feed-activity-card papabear:max-w-[550px]" data-activity-urn="urn:li:activity:7259228842119114754" data-featured-activity-urn="urn:li:activity:7259183824532566020" data-attributed-urn="urn:li:share:7259183823811227648" data-id="main-feed-card">  <p class="!text-sm text-color-text mb-1 pb-[10px] border-b-1 border-solid border-color-border-faint main-feed-activity-card__header mx-main-feed-card-no-gutter px-main-feed-card-no-gutter"> <a href="https://www.linkedin.com/company/nonabiosciences?trk=organization_guest_main-feed-card_feed-reaction-header" class="link-styled" data-tracking-control-name="organization_guest_main-feed-card_feed-reaction-header" data-tracking-will-navigate="true" target="_self">Nona Biosciences</a> reposted this </p> <div class="flex items-center font-sans mb-1" data-test-id="main-feed-activity-card__entity-lockup"> <a href="https://nl.linkedin.com/in/xiangyu-rao-phd-mba-86788a14?trk=organization_guest_main-feed-card_feed-actor-image" class="relative" data-tracking-control-name="organization_guest_main-feed-card_feed-actor-image" data-tracking-will-navigate> <img class="inline-block relative rounded-[50%] w-6 h-6 " data-delayed-url="https://media.licdn.com/dms/image/v2/D4E03AQFgrLqxcVVKgA/profile-displayphoto-shrink_400_400/profile-displayphoto-shrink_400_400/0/1716390081817?e=2147483647&v=beta&t=KT5vdkxAoYFRcL7PgsGYfmZouWL2NogV9tbYuPTVlpI" data-ghost-classes="bg-color-entity-ghost-background" data-ghost-url="https://static.licdn.com/aero-v1/sc/h/9c8pery4andzj6ohjkjp54ma2" alt="View profile for Xiangyu Rao, PHD, MBA, graphic">  </a> <div class="flex flex-col self-start min-w-0 ml-1 "> <div class="text-color-text "> <a class="text-sm link-styled no-underline leading-open" href="https://nl.linkedin.com/in/xiangyu-rao-phd-mba-86788a14?trk=organization_guest_main-feed-card_feed-actor-name" data-tracking-control-name="organization_guest_main-feed-card_feed-actor-name" aria-label="View profile for Xiangyu Rao, PHD, MBA" data-tracking-will-navigate> Xiangyu Rao, PHD, MBA </a>  </div> <p class="!text-xs text-color-text-low-emphasis leading-[1.33333] m-0 truncate">  Business Development @ Nona Biosciences | Executive MBA </p> <span class="!text-xs text-color-text-low-emphasis leading-[1.33333] flex"> <time class="flex-none"> 2w  </time>  </span> </div>  </div> <div class="ellipsis-menu absolute right-0 top-0 !mr-0.5" data-test-id="main-feed-activity-card__ellipsis-menu"> <div class="collapsible-dropdown flex items-center relative hyphens-auto"> <button class="ellipsis-menu__trigger collapsible-dropdown__button btn-md btn-tertiary cursor-pointer !py-[6px] !px-1 flex items-center rounded-[50%] " aria-expanded="false" aria-label="Open menu" data-tracking-control-name="organization_guest_main-feed-card_ellipsis-menu-trigger" tabindex="0"> <icon class="ellipsis-menu__trigger-icon 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data-test-id="main-feed-activity-card__commentary">Looking forward to PEGS Europe! If you’re working on Antibody drug development with specific interests of TCR Mimic Antibody / Single Domain Antibody applications in Immunotherapies, visit me at poster section · A085 Single Domain CD3 Antibody Enables Next-Generation T Cell Engagers for Enhanced Immunotherapies · B080 Discovery of T-Cell Receptor Mimic Antibody Derived T-Cell Engager I will be talking about how our Harbour mice platform leverage the antibody based immunotherapies developments Excited to share ideas and learn from everyone there. Hope to see you! <a class="link" href="https://lnkd.in/e6FvjGpE?trk=organization_guest_main-feed-card-text" target="_self" rel="nofollow" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>https://lnkd.in/e6FvjGpE</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Ffullyhumanantibody&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#FullyHumanAntibody</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fpegseurope&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#PEGSEurope</a> <a class="link" 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data-tracking-control-name="organization_guest_main-feed-card_feed-actor-name" aria-label="View organization page for Nona Biosciences" data-tracking-will-navigate> Nona Biosciences </a>  </div> <p class="!text-xs text-color-text-low-emphasis leading-[1.33333] m-0 truncate">  5,629 followers </p> <span class="!text-xs text-color-text-low-emphasis leading-[1.33333] flex"> <time class="flex-none"> 3w <span aria-hidden="true" class="text-color-text-low-emphasis before:middot"></span> <span> Edited </span> </time>  </span> </div>  </div> <div class="ellipsis-menu absolute right-0 top-0 !mr-0.5" data-test-id="main-feed-activity-card__ellipsis-menu"> <div class="collapsible-dropdown flex items-center relative hyphens-auto"> <button class="ellipsis-menu__trigger collapsible-dropdown__button btn-md btn-tertiary cursor-pointer !py-[6px] !px-1 flex items-center rounded-[50%] " aria-expanded="false" aria-label="Open menu" 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whitespace-pre-wrap break-words " dir="ltr" data-test-id="main-feed-activity-card__commentary">🌟 Join Nona Biosciences at World ADC 2024! 🌟 📍 Booth #417 🗓️ Presentation: Wednesday, November 6th ⏰ Time: 12:30 PM 🎤 Speaker: <a class="link" href="https://www.linkedin.com/in/musheng-bao-79191b32?trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>Musheng Bao</a>, Vice President, Head of Biology Topic: Discovery and Preclinical Validation of a Novel Enzyme Cleavable Linker for Development of Next-Gen ADC Against Solid Tumors Summary: Tackling the challenges of poor drug penetration and high tumor heterogeneity in ADC and other biologics, Nona Bioscience has developed a groundbreaking linker technology. This innovative linker leverages a unique cleavage mechanism, utilizing an enzyme abundant in the tumor microenvironment (TME) of solid tumors. Paired with our proprietary payloads, it enables efficient, tumor-specific release, independent of internalization. Our preclinical data shows promising efficacy and safety improvements with this linker-payload system. Don’t miss this opportunity to learn about the next generation of targeted cancer therapies!</p>  </div> <ul class="grid grid-cols-6 grid-rows-[60%_40%] w-main-feed-card-media feed-images-content list-none pl-0 " data-test-id="feed-images-content"> <li class="bg-color-background-container-tint text-[0px] col-span-full row-span-full " data-test-id="feed-images-content__list-item" data-position="0"> <img class="lazy-load w-full object-cover object-center h-full babybear:max-h-[400px]" data-delayed-url="https://media.licdn.com/dms/image/v2/D4E22AQHuagVxvbqDEQ/feedshare-shrink_2048_1536/feedshare-shrink_2048_1536/0/1730216153881?e=2147483647&v=beta&t=Kamxe7IaIemikPkG8taft0ZTf6FtF4P5rUqJk9L7r-E" data-ghost-url="https://static.licdn.com/aero-v1/sc/h/921ynb2z53z33mhm3061qvjag" alt="No alternative text description for this image">  </li> </ul>    <code id="i18n_reaction_singular" style="display: none"></code> <code id="i18n_reactions_plural" style="display: none"></code> <div class="flex 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𝗞𝗲𝘆 𝗙𝗲𝗮𝘁𝘂𝗿𝗲𝘀: 🌟 HBICE® Technology — Unleashing bispecifics, multispecifics, immunocytokines, and other cutting-edge formats with enhanced structure, size reduction, and chain simplicity. 🌟 Breakthrough Therapeutic Modalities — Designed for powerful applications in ADCs, RDCs, PROTACs, and other areas demanding precision, efficiency, and adaptability. 🌟 Superior Performance in CAR Therapies — HCAbs from our HCAb Harbour Mice® deliver reduced immunogenicity, high solubility, tissue penetration, and conjugation benefits, ideal for advanced CAR-based cell therapies. 🌟 Pioneering mRNA Therapies & Targeted Delivery — The compact size and structural benefits of HCAbs enable next-level mRNA designs and LNP modifications, opening up new avenues in targeted treatments. Nona Biosciences is leading the way with highly stable, low-immunogenic, fully human HCAbs for breakthrough therapies. Explore the future of therapeutic innovation with HCAb PLUS™: <a class="link" href="https://lnkd.in/ecfYaq5u?trk=organization_guest_main-feed-card-text" target="_self" rel="nofollow" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>https://lnkd.in/ecfYaq5u</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fantibodies&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#antibodies</a> <a class="link" href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Ffullyhuman&trk=organization_guest_main-feed-card-text" target="_self" data-tracking-control-name="organization_guest_main-feed-card-text" data-tracking-will-navigate>#fullyhuman</a> <a class="link" 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data-delayed-url="https://media.licdn.com/dms/image/v2/C560BAQE1Hvk5CZp_oQ/company-logo_200_200/company-logo_200_200/0/1668124699478?e=2147483647&v=beta&t=ABdDkAfbYKvnOMECeo3ubSt3g5mRwz-OeCHiLtFRfds" data-ghost-classes="bg-color-entity-ghost-background" data-ghost-url="https://static.licdn.com/aero-v1/sc/h/cs8pjfgyw96g44ln9r7tct85f" alt> <h2 class="contextual-sign-in-modal__context-screen-title font-sans text-xl text-color-text my-2 mx-4 text-center" id="base-contextual-sign-in-modal-modal-header"> Stay updated with Nona Biosciences </h2>  <div class="contextual-sign-in-modal__btn-container m-auto w-[320px] babybear:w-full">  <div class="w-full max-w-[400px] mx-auto"> <div class="google-auth-button">  <div class="google-auth-button__placeholder " data-theme="filled_blue" data-logo-alignment="center"></div>  </div> </div> <div class="sign-in-modal" data-impression-id="organization_guest_contextual-sign-in-modal_sign-in-modal"> <button class="sign-in-modal__outlet-btn cursor-pointer btn-md btn-primary btn-secondary" data-tracking-client-ingraph data-tracking-control-name="organization_guest_contextual-sign-in-modal_sign-in-modal_outlet-button" data-modal="base-sign-in-modal">  Sign in </button> <div class>  <div id="base-sign-in-modal" class="modal modal--sign-in" data-outlet="base-sign-in-modal">  <div class="modal__overlay flex items-center bg-color-background-scrim justify-center fixed bottom-0 left-0 right-0 top-0 opacity-0 invisible pointer-events-none z-[1000] transition-[opacity] ease-[cubic-bezier(0.25,0.1,0.25,1.0)] duration-[0.17s] py-4 " aria-hidden="true"> <section aria-modal="true" role="dialog" aria-labelledby="base-sign-in-modal-modal-header" tabindex="-1" class="max-h-full modal__wrapper overflow-auto p-0 bg-color-surface max-w-[1128px] min-h-[160px] relative scale-[0.25] shadow-sm shadow-color-border-faint transition-[transform] ease-[cubic-bezier(0.25,0.1,0.25,1.0)] duration-[0.33s] focus:outline-0 w-[1128px] mamabear:w-[744px] babybear:w-[360px] rounded-md"> <button class="modal__dismiss btn-tertiary h-[40px] w-[40px] p-0 rounded-full indent-0 sign-in-modal__dismiss absolute right-0 cursor-pointer m-[20px]" aria-label="Dismiss" data-tracking-control-name="organization_guest_contextual-sign-in-modal_sign-in-modal_dismiss"> <icon class="sign-in-modal__dismiss-icon" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/gs508lg3t2o81tq7pmcgn6m2"></icon> </button> <div class="modal__main w-full"> <div class="sign-in-modal__screen flex flex-col py-4 w-[513px] babybear:w-full px-3"> <h2 class="sign-in-modal__header font-sans text-display-md text-color-text "> Welcome back </h2> <code id="i18n_sign_in_form_show_text" style="display: none"></code> <code id="i18n_sign_in_form_show_label" style="display: none"></code> <code id="i18n_sign_in_form_hide_text" style="display: none"></code> <code id="i18n_sign_in_form_hide_label" style="display: none"></code> <code id="i18n_username_error_empty" style="display: none"></code> <code id="i18n_username_error_too_long" style="display: none"></code> <code id="i18n_username_error_too_short" style="display: none"></code> <code id="i18n_password_error_empty" style="display: none"></code> <code id="i18n_password_error_too_short" style="display: none"></code> <code id="i18n_password_error_too_long" style="display: none"></code>  <form data-id="sign-in-form" action="https://www.linkedin.com/uas/login-submit" method="post" novalidate class="mt-1.5 mb-2"> <input name="loginCsrfParam" value="583a9429-9bf6-492f-8066-bb7057195309" type="hidden"> <div class="flex flex-col"> <div class="mt-1.5" data-js-module-id="guest-input"> <div class="flex flex-col"> <label class="input-label mb-1" for="base-sign-in-modal_session_key"> Email or phone </label> <div class="text-input flex"> <input class="text-color-text font-sans text-md outline-0 bg-color-transparent grow" autocomplete="username" id="base-sign-in-modal_session_key" name="session_key" required data-tracking-control-name="organization_guest_contextual-sign-in-modal_sign-in-modal_sign-in-session-key" data-tracking-client-ingraph type="text"> </div> </div> <p class="input-helper mt-1.5" for="base-sign-in-modal_session_key" role="alert" data-js-module-id="guest-input__message"></p> </div> <div class="mt-1.5" data-js-module-id="guest-input"> <div class="flex flex-col"> <label class="input-label mb-1" for="base-sign-in-modal_session_password"> Password </label> <div class="text-input flex"> <input class="text-color-text font-sans text-md outline-0 bg-color-transparent grow" autocomplete="current-password" id="base-sign-in-modal_session_password" name="session_password" required data-tracking-control-name="organization_guest_contextual-sign-in-modal_sign-in-modal_sign-in-password" data-tracking-client-ingraph type="password"> <button aria-live="assertive" aria-relevant="text" data-id="sign-in-form__password-visibility-toggle" class="font-sans text-md font-bold text-color-action z-10 ml-[12px] hover:cursor-pointer" aria-label="Show your LinkedIn password" data-tracking-control-name="organization_guest_contextual-sign-in-modal_sign-in-modal_sign-in-password-visibility-toggle-btn" type="button">Show</button> </div> </div> <p class="input-helper mt-1.5" for="base-sign-in-modal_session_password" role="alert" data-js-module-id="guest-input__message"></p> </div> <input name="session_redirect" value="https://www.linkedin.com/company/nonabiosciences" type="hidden">  </div> <div data-id="sign-in-form__footer" class="flex justify-between sign-in-form__footer--full-width"> <a data-id="sign-in-form__forgot-password" class="font-sans text-md font-bold link leading-regular sign-in-form__forgot-password--full-width" href="https://www.linkedin.com/uas/request-password-reset?trk=organization_guest_contextual-sign-in-modal_sign-in-modal_forgot_password" data-tracking-control-name="organization_guest_contextual-sign-in-modal_sign-in-modal_forgot_password" data-tracking-will-navigate>Forgot password?</a>  <input name="trk" value="organization_guest_contextual-sign-in-modal_sign-in-modal_sign-in-submit" type="hidden"> <button class="btn-md btn-primary flex-shrink-0 cursor-pointer sign-in-form__submit-btn--full-width" data-id="sign-in-form__submit-btn" data-tracking-control-name="organization_guest_contextual-sign-in-modal_sign-in-modal_sign-in-submit-btn" data-tracking-client-ingraph data-tracking-litms type="submit"> Sign in </button> </div> <div class="sign-in-form__divider left-right-divider pt-2 pb-3"> <p class="sign-in-form__divider-text font-sans text-sm text-color-text px-2"> or </p> </div> </form> <div class="w-full max-w-[400px] mx-auto"> <div class="google-auth-button" data-tracking-control-name="organization_guest_contextual-sign-in-modal_sign-in-modal_google-auth-button" data-tracking-client-ingraph> <code id="isTermsAndConditionsSkipEnabledAuthButton" style="display: none"></code> <p class="linkedin-tc__text text-color-text-low-emphasis text-xs pb-2" data-impression-id="organization_guest_contextual-sign-in-modal_sign-in-modal__button-skip-tc-text"> By clicking Continue to join or sign in, you agree to LinkedIn’s <a href="/legal/user-agreement?trk=organization_guest_contextual-sign-in-modal_sign-in-modal_auth-button_user-agreement" target="_blank" data-tracking-control-name="organization_guest_contextual-sign-in-modal_sign-in-modal_auth-button_user-agreement" data-tracking-will-navigate="true">User Agreement</a>, <a href="/legal/privacy-policy?trk=organization_guest_contextual-sign-in-modal_sign-in-modal_auth-button_privacy-policy" target="_blank" data-tracking-control-name="organization_guest_contextual-sign-in-modal_sign-in-modal_auth-button_privacy-policy" data-tracking-will-navigate="true">Privacy Policy</a>, and <a href="/legal/cookie-policy?trk=organization_guest_contextual-sign-in-modal_sign-in-modal_auth-button_cookie-policy" target="_blank" data-tracking-control-name="organization_guest_contextual-sign-in-modal_sign-in-modal_auth-button_cookie-policy" data-tracking-will-navigate="true">Cookie Policy</a>. </p> <div class="google-auth-button__placeholder google-auth-button__placeholder--black-border" data-theme="outline" data-logo-alignment="center"></div>  </div> </div>  <p class="sign-in-modal__join-now m-auto font-sans text-md text-color-text mt-2"> New to LinkedIn? <a href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww%2Elinkedin%2Ecom%2Fcompany%2Fnonabiosciences&trk=organization_guest_contextual-sign-in-modal_sign-in-modal_join-link" data-tracking-control-name="organization_guest_contextual-sign-in-modal_sign-in-modal_join-link" data-tracking-will-navigate="true" class="sign-in-modal__join-link">Join now</a> </p> </div> </div>  </section> </div> </div> </div> </div> <div class="contextual-sign-in-modal__divider left-right-divider"> <p class="contextual-sign-in-modal__divider-text font-sans text-sm text-color-text px-2"> or </p> </div> </div> <p class="contextual-sign-in-modal__join-now m-auto font-sans text-md text-color-text my-1"> New to LinkedIn? <a href="https://www.linkedin.com/signup?session_redirect=https%3A%2F%2Fwww%2Elinkedin%2Ecom%2Fcompany%2Fnonabiosciences&trk=organization_guest_contextual-sign-in-modal_join-link" data-tracking-control-name="organization_guest_contextual-sign-in-modal_join-link" data-tracking-will-navigate="true" class="contextual-sign-in-modal__join-link">Join now</a> </p> <p class="linkedin-tc__text text-color-text-low-emphasis text-xs pb-2 contextual-sign-in-modal__terms-and-conditions m-auto w-[320px] pt-2 babybear:w-full" data-impression-id="linkedin-tc__button-skip-tc-text"> By clicking Continue to join or sign in, you agree to LinkedIn’s <a href="/legal/user-agreement?trk=linkedin-tc_auth-button_user-agreement" target="_blank" data-tracking-control-name="linkedin-tc_auth-button_user-agreement" data-tracking-will-navigate="true">User Agreement</a>, <a href="/legal/privacy-policy?trk=linkedin-tc_auth-button_privacy-policy" target="_blank" data-tracking-control-name="linkedin-tc_auth-button_privacy-policy" data-tracking-will-navigate="true">Privacy Policy</a>, and <a href="/legal/cookie-policy?trk=linkedin-tc_auth-button_cookie-policy" target="_blank" data-tracking-control-name="linkedin-tc_auth-button_cookie-policy" data-tracking-will-navigate="true">Cookie Policy</a>. </p> </div> </div>  </section> </div> </div> </div> </div> <div class="cta-modal overflow-hidden container-raised z-10 fixed bottom-3 right-3 min-h-[56px] p-2 babybear:hidden windows-app-upsell windows-app-upsell--msft flex flex-col p-2 w-[359px] !bg-[#F1F8FA] opacity-90 backdrop-blur-[2px] z-1" data-impression-id="organization_guest_windows-app-upsell_cta-modal" role="dialog" aria-labelledby="cta-modal-header" aria-describedby="cta-modal-subheader"> <div class="windows-app-upsell__linkedin-title-container pt-[6px] mb-1.5 flex align-center"> <icon class="windows-app-upsell__linkedin-bug-icon block w-[21px] h-[21px]" data-svg-class-name="windows-app-upsell__linkedin-bug-icon-svg w-[21px] h-[21px]" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/euqjj7tf5wvr33frd3x1jj9s"></icon> <p class="windows-app-upsell__linkedin-title uppercase text-xs text-color-text-secondary leading-[21px] ml-1"> LinkedIn </p> </div> <p class="windows-app-upsell__title font-sans text-md text-color-text-accent-4-hover font-semibold leading-regular mb-1"> LinkedIn is better on the app </p> <p class="windows-app-upsell__body font-sans text-sm text-color-text-secondary leading-regular"> Don’t have the app? Get it in the Microsoft Store. </p> <a class="windows-app-upsell__cta btn-sm btn-secondary-emphasis mt-2 mb-[6px] w-fit" href="ms-windows-store://pdp/?ProductId=9WZDNCRFJ4Q7&mode=mini&cid=guest_desktop_upsell" data-tracking-client-ingraph data-tracking-control-name="organization_guest_windows-app-upsell_cta" data-tracking-will-navigate> Open the app </a> <button class="cta-modal__dismiss-btn absolute h-4 w-4 p-1 top-2 right-2 hover:cursor-pointer focus:outline focus:outline-2 focus:outline-color-action" data-tracking-control-name="organization_guest_windows-app-upsell_dismiss" aria-label="Dismiss"> <icon class="cta-modal__dismiss-icon block h-2 w-2 onload" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/adzjokfylbe8pvjr9h8iv96mw"></icon> </button> </div> </div> <code id="disableOneTapOnInit" style="display: none"></code> <code id="flagshipOrganizationTracking" style="display: none"></code> <script src="https://static.licdn.com/aero-v1/sc/h/7itt46rafycxiwozfd111d2we" async></script>  <script src="https://static.licdn.com/aero-v1/sc/h/eef4p9np6sualhph80ir8m1im" async defer></script> <script data-delayed-url="https://static.licdn.com/aero-v1/sc/h/19m2m2iij3pcbxe4bkogyzklj" data-module-id="media-player"></script>  </body> </html>

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