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class="page_header" style="background-image:url(https://medicalevents.com/sites/default/files/block-background/page-header.jpg)"><div class="container"><div class="row"><div class="col-sm-12 text-center"><h1 class="text-uppercase">Next-Generation Degraders & Glues 2022 London United Kingdom</h1></div></div></div></section></div></div><div class="region region-highlighted"><div class="page_linker"><div class="container"><div class="row"><div class="col-sm-12 text-center"><div id="block-envas-breadcrumbs" class="block block-system block-system-breadcrumb-block"> <nav role="navigation" aria-labelledby="system-breadcrumb"><h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2><ul class="breadcrumb"><li> <a href="/index.php/"> <i class="icon-home6"></i> Home</a></li><li> Next-Generation Degraders & Glues 2022 London United Kingdom</li></ul> </nav></div></div></div></div></div></div><div class="contentPage"><div class="container"><div class="row"><div class="col-sm-9"><div class="region region-content"><div data-drupal-messages-fallback class="hidden"></div><div id="block-envas-content" class="block block-system block-system-main-block"> <article data-history-node-id="2012" class="node node--type-events node--view-mode-full"><div class="node__content"><div class="layout layout--onecol"><div class="layout__region layout__region--content"><div class="field field--name-field-image field--type-image field--label-hidden field__items"><div class="field__item"> <img loading="lazy" src="/sites/default/files/2022-11/ubqe-header.jpg" width="1919" height="360" alt="" /></div></div><div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-above"><div class="field__label">Event Description</div><div class="field__item"><p>Next-Generation Degraders & Glues 2022 London United Kingdom</p><p>The 2nd Annual conference on Next-Generation Degraders & Glues brings together experts in the field to discuss the new therapeutic modalities detailed below, as well as issues underlying the use of targeted degradation as a new therapeutic approach.<br><br>The ubiquitin-proteasome, lysosome, and autophagy systems are all well-controlled, selective degradation pathways that are key cellular regulators in cancer, CNS, and other diseases. A new generation of hetero bi-functional chimeras and small molecule monovalent degraders are being developed to hijack these systems for targeted protein degradation or stabilization. These molecules that include Proteolysis-targeting chimeras (PROTACs) and molecular glues are being used to seek out previously “undruggable” targets for therapeutic intervention. However, challenges do exist in terms of specificity, stability, biodistribution, and penetration of these degrader molecules.</p><p>Submit a speaker proposal, register, or become a sponsor!</p></div></div><div class="field field--name-field-end-date field--type-datetime field--label-inline clearfix"><div class="field__label">End Date</div><div class="field__item"><time datetime="2023-06-22T15:00:00Z" class="datetime">Thu, 06/22/2023 - 17:00</time></div></div><div class="field field--name-field-start-date field--type-datetime field--label-inline clearfix"><div class="field__label">Start Date</div><div class="field__item"><time datetime="2023-06-20T06:00:00Z" class="datetime">Tue, 06/20/2023 - 08:00</time></div></div><div class="field field--name-field-website field--type-link field--label-inline clearfix"><div class="field__label">Event website</div><div class="field__item"><a href="https://www.degradersandglues.com/">Visit Website</a></div></div><div class="field field--name-field-organizer field--type-entity-reference field--label-inline clearfix"><div class="field__label">Organizer</div><div class="field__items"><div class="field__item"><a href="/index.php/organizer/cambridge-healthtech-institute" hreflang="en">Cambridge Healthtech Institute</a></div></div></div><div class="field field--name-field-e field--type-entity-reference field--label-inline clearfix"><div class="field__label">Event Speciality</div><div class="field__items"><div class="field__item"><a href="/index.php/category/biomedical-engineering" hreflang="en">Biomedical Engineering</a></div><div class="field__item"><a href="/index.php/category/bio-engineering" hreflang="en">Bio-Engineering</a></div><div class="field__item"><a href="/index.php/category/infectious-diseases" hreflang="en">Infectious Diseases</a></div><div class="field__item"><a href="/index.php/category/oncology" hreflang="en">Oncology</a></div></div></div><div class="field field--name-field-venue field--type-entity-reference field--label-inline clearfix"><div class="field__label">Venue</div><div class="field__item"><a href="/index.php/venue/hilton-london-canary-wharf" hreflang="en">Hilton London Canary Wharf</a></div></div><div class="field field--name-field-for-tickets-purchase field--type-string field--label-inline clearfix"><div class="field__label">For registration/tickets purchase:</div><div class="field__item">https://www.degradersandglues.com/register/next-generation-degraders-and-glues</div></div><div class="field field--name-field-currency-symbol field--type-string field--label-inline clearfix"><div class="field__label">Currency Symbol:</div><div class="field__item">£</div></div><div class="field field--name-field-event-cost field--type-string field--label-inline clearfix"><div class="field__label">Event Cost:</div><div class="field__item">2,599</div></div><div class="field field--name-field-event-sessions field--type-entity-reference-revisions field--label-hidden field__items"><div class="field__item"><div class="paragraph-formatter"><div class="paragraph-info"></div><div class="paragraph-summary"><div class="paragraphs-description paragraphs-collapsed-description"><div class="paragraphs-content-wrapper"><span class="summary-content">Designing and Optimizing PROTACs, Molecular Glues, and Other Degrader Modalities</span></div></div></div></div></div></div><div class="field field--name-field-event-type field--type-list-string field--label-inline clearfix"><div class="field__label">Event Types (Select all that apply)</div><div class="field__items"><div class="field__item">Medical Convention</div><div class="field__item">Medical Conference</div><div class="field__item">Medical Seminar</div></div></div><div class="field field--name-field-registration-contact field--type-string field--label-inline clearfix"><div class="field__label">Event Registration Contact Email</div><div class="field__item">reg@healthtech.com</div></div><div class="field field--name-field-event-information-contact field--type-string field--label-inline clearfix"><div class="field__label">Event Information Contact Email</div><div class="field__item">chi@healthtech.com</div></div><div class="field field--name-field-cme-credit-hours-available field--type-boolean field--label-above"><div class="field__label">CME Credits</div><div class="field__item">No</div></div><div class="field field--name-field-abstraction-date field--type-datetime field--label-above"><div class="field__label">Abstract Submission Deadline</div><div class="field__item"><time datetime="2023-06-20T06:00:00Z" class="datetime">Tue, 06/20/2023 - 08:00</time></div></div></div></div></div></article></div><div id="block-googlemapblock" class="block block-common-feature block-googlemapblock"><iframe src="https://maps.google.com/maps?q=South Quay, Marsh Wall London United Kingdom&z=10&output=embed" width="100%" height="450" frameborder="0" style="border:0;" allowfullscreen=""> </iframe></div><div 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