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Healio: Medical News, Journals, and Free CME

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"/> 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<h2> <a id="layout_0_phmaincontent_0_hlTitle" href="/web/20130901160555/http://www.healio.com/cardiology/vascular-medicine/news/online/{AAE53ACC-E91F-4A27-89C8-623F278CC81A}/RE-ALIGN-Dabigatran-use-not-supported-in-patients-with-mechanical-heart-valves">RE-ALIGN: Dabigatran use not supported in patients with mechanical heart valves</a> </h2> <ul class="meta-info"> <li> September 1, 2013</li> </ul> <!-- figure --> <!-- /figure --> <p> <p>AMSTERDAM &#x2014; Use of dabigatran in patients with mechanical heart valves was associated with increased rates of thromboembolic events and bleeding complications in the RE-ALIGN study.</p><p>The phase 2, dose-validation study focused on two patient populations: those who had undergone aortic or mitral valve replacement within the week before the study and those who had undergone replacement at least 3 months before the study.</p><a id="layout_0_phmaincontent_0_hlFullStory" class="jump-link" 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id="tab-headlines" class="panes"> <ul> <li> <h4> <a href="/web/20130901160555/http://www.healio.com/cardiology/intervention/news/online/{15809DD1-CBB4-44B6-9FCC-D921FCF1ABA1}/ACCOAST-Prasugrel-pretreatment-increases-major-bleeding-does-not-benefit-ischemic-events"> ACCOAST: Prasugrel pretreatment increases major bleeding, does not benefit ischemic events </a></h4> </li> <li class="meta-info"> September 1, 2013</li> </ul> <ul> <li> <h4> <a href="/web/20130901160555/http://www.healio.com/cardiology/vascular-medicine/news/online/{B826A3FC-0ADA-4429-9672-06A2CCE801FC}/Edoxaban-after-initial-heparin-found-noninferior-to-standard-therapy"> Edoxaban after initial heparin found noninferior to standard therapy</a></h4> </li> <li class="meta-info"> September 1, 2013</li> </ul> <ul> <li> <h4> <a href="/web/20130901160555/http://www.healio.com/cardiology/intervention/news/online/{46FB1353-2C20-44AD-A7B3-3C873EFF53A6}/TAO-Otamixaban-does-not-improve-outcomes-in-NSTEACS"> TAO: Otamixaban does not 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