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checked item */ ul.inputs-list.multi-container li.hs-form-checkbox label span::after, .hs-form-booleancheckbox-display span::after { content: ""; border: 2px solid #d9d9d9; border-radius: 3px; height: 20px; left: 0px; position: absolute; top: 0px; width: 20px; background: #fff; z-index: 0; display: block; transition-property: background-color, border-color, -webkit-box-shadow; -o-transition-property: background-color, border-color, box-shadow; transition-property: background-color, border-color, box-shadow; transition-property: background-color, border-color, box-shadow, -webkit-box-shadow; } /* Show when checked */ ul.inputs-list.multi-container li.hs-form-checkbox label input:checked + span::after, .hs-form-booleancheckbox-display input:checked + span::after, ul.inputs-list.multi-container li.hs-form-checkbox label input:checked + span::before, .hs-form-booleancheckbox-display input:checked + span::before{ opacity: 1; } .hs-form-booleancheckbox-display input:checked+label:after, .hs-form-booleancheckbox-display input:checked+label:after { background: #fff; border-color: #157479; } /* Style when focused */ ul.inputs-list.multi-container li.hs-form-checkbox label input:focus + span::after, .hs-form-booleancheckbox-display input:focus + span::after { outline: 3px solid transparent; /* For Windows high contrast mode. */ box-shadow: 0 0 .3125rem rgba(0, 0, 0, .3); border-color: #157479; } .hs_contact_country{ clear: both; } .hs-button { border-radius: 65px !important; font-size: 14px; line-height: 1.3; letter-spacing: 1.12px; font-family: "Roboto Slab", helvetica, arial, sans-serif; font-weight: 700 !important; padding: 19px 23px !important; border: 2px solid; display: inline-block; text-decoration: none; text-transform: uppercase; -webkit-appearance: none !important; -moz-appearance: none !important; appearance: none !important; } .hbspt-form textarea{max-width: 100% !important; height: 186px !important; resize: none;} .hbspt-form textarea:focus{border: 1px solid #74cbc8 !important;} .hs-fieldtype-textarea .invalid.error{border: 2px solid #E74949 !important;} .hbspt-form fieldset{max-width: 100% !important; margin-bottom: 60px;} .hbspt-form .field {margin-bottom: 27px} .hs_recaptcha{ margin-top: 23px !important; margin-bottom: 27px !important; } .hs-button, .hs-form-field input[type=text], .hs-form-field input[type=email], .hs-form-field input[type=phone], .hs-form-field input[type=number], .hs-form-field input[type=tel], .hs-form-field input[type=date], .hs-form-field textarea { appearance: none; -webkit-appearance: none; -moz-appearance: none; } .hs-default-font-element, .hs-main-font-element { font-family: "Roboto Slab", helvetica, arial, sans-serif; } .hbspt-form .hs-button { white-space: pre-wrap } .hbspt-form .hs-richtext { word-break: break-word } .hbspt-form.submitted-message { overflow: auto } .hbspt-form fieldset.form-columns-1 .hs-input { width: 95% } .hbspt-form fieldset.form-columns-1 .input { margin-right: 0px !important } .hbspt-form fieldset.form-columns-1 input[type=checkbox], .hbspt-form fieldset.form-columns-1 input[type=radio] { width: auto } .hbspt-form fieldset.form-columns-2 .hs-form-field { width: 50%; float: left } .hbspt-form fieldset.form-columns-2 .input { margin-right: 0px !important; } .hbspt-form fieldset.form-columns-3 .hs-form-field { width: 32.7%; float: left } .hbspt-form fieldset.form-columns-3 .input { margin-right: 8px } .hbspt-form label.hs-hidden { visibility: hidden } .hbspt-form .hs-field-desc { width: 100% } .hs-custom-style .hs-input, .hs-custom-style fieldset { max-width: 100% } .hs-custom-style>div.form-columns-3 .hs-form-field, .hs-custom-style fieldset.form-columns-3 .hs-form-field { width: 33.3% } .hs-custom-style>div>div:last-of-type .hs-input:not([type=checkbox]):not([type=radio]), .hs-custom-style fieldset>div:last-of-type .hs-input:not([type=checkbox]):not([type=radio]) { width: 100%; max-width: 100% } .hs-custom-style>div input:not([type=image]):not([type=submit]):not([type=button]):not([type=radio]):not([type=checkbox]):not([type=file]), .hs-custom-style fieldset input:not([type=image]):not([type=submit]):not([type=button]):not([type=radio]):not([type=checkbox]):not([type=file]) { box-sizing: border-box; padding: 0 15px; min-height: 27px } .hs-custom-style>div textarea, .hs-custom-style fieldset textarea { padding: 10px 15px } .hs-custom-style .hs-dependent-field>div .hs-input:not([type=checkbox]):not([type=radio]) { width: 100% } .legal-consent-container .field.hs-form-field { margin-bottom: 8px } .legal-consent-container .hs-field-desc.checkbox-desc { margin: -12px 0 0 21px } .legal-consent-container .hs-form-booleancheckbox-display input { float: left } .legal-consent-container .hs-form-booleancheckbox-display>span { display: block !important; margin-left: 30px !important; } .legal-consent-container .hs-form-booleancheckbox-display p { margin: 0; display: inline } .legal-consent-container .hs-error-msgs label { color: #f2545b } .legal-consent-container~.hs_recaptcha { margin-top: 18px } .cookie-reset-container { font-size: 14px; margin-bottom: 10px; text-align: right } #hs-outer-captcha-target, #hs-outer-captcha-target * { display: none; height: 0; width: 0 } .hubspot-link__container { font-size: 14px; padding-bottom: 40px; position: relative; color: #9fa0a2; font-family: "Roboto Slab", helvetica, arial, sans-serif; } .hubspot-link-text { color: #00a4bd; font-weight: 400 } .hubspot-link__container.sproket { color: #9fa0a2 } .hubspot-link { color: #9fa0a2 } .hubspot-link, .hubspot-link:hover { text-decoration: none } .hubspot-link:hover .hubspot-link-text { text-decoration: underline } .hubspot-link__icon { margin-bottom: -1px; margin-right: 5px } .hubspot-link__container.sproket .hubspot-link__icon { width: 30px; margin-right: 0; float: left; margin-top: -9px; margin-left: -5px } .hubspot_signup_form .hs_email{margin-bottom: 0px !important; width: 80% !important; float: left !important;} .hubspot_signup_form .hs_submit{width: 20% !important; float: left !important; } .hubspot_signup_form .hs-button{padding: 12.5px 15px !important;} .hubspot_signup_form .hs_email label{display: none !important;} .hubspot_signup_form ul.no-list{position: absolute !important; top: 48px !important;} .hubspot_signup_form {position: relative !important;} .hubspot_signup_form .submitted-message{color: #ab8940 !important; font-size: 22px !important; } .hubspot_white .hbspt-form label, .hubspot_white .hs-form-required { color: #fff; } .hubspot_white .hs-input, .hubspot_white ul.inputs-list.multi-container li.hs-form-checkbox label span::before, .hubspot_white .hs-form-booleancheckbox-display span::before{ background-color: #fff !important; } .hubspot_white .hs_submit { text-align: center; } .hubspot_white .hs-form select.is-placeholder { opacity: 1; } .hubspot_white ul.inputs-list.multi-container li.hs-form-checkbox label span::after, .hubspot_white .hs-form-booleancheckbox-display span::after { border-color: #3f4852; } input[type=submit].hs-button.primary.large{ color: #fff; background: #00181e; border-color: #00181e !important; } input[type=submit].hs-button.primary.large:hover { background: #74cbc8 !important; border-color: #74cbc8 !important; } /***/ .hbspt-form .hs-input[type=checkbox]{ cursor: pointer; } .hs-form-booleancheckbox-display input:checked + span::after{ background: #fff; border-color: #157479; } .hbspt-form .form-columns-2 { display: flex; flex-flow: row wrap; -webkit-box-direction: normal; } .hbspt-form .hs_firstname { flex: 1; -webkit-box-flex: 1; } .hbspt-form .hs_submit{ margin-top: 60px; } .newsletter-form .hs_submit{margin-top: 45px;} .newsletter-form form .gfield_consent_description { border: none !important; } /*New Landing page*/ .landing-middle-section{ padding-right: 0px !important; } .left-col{max-width:93%} .left-col-para{padding-right:30px;} .left-col video{border-radius:4px;} /* Kit asssesment */ .kits_form_col .hbspt-form .hs-input[type=checkbox] { height: 20px !important; width: 20px !important; } .kits_form_col {padding-bottom: 45px;} .hs-richtext h4 {margin-bottom: 15px !important;} .kits_form_col label.hs-form-checkbox-display {margin-bottom: 15px;} .kits_form_col .hbspt-form li.hs-form-checkbox label span{ margin-left: 0px !important; padding-left: 31px; } .hbspt-form label.hs-form-radio-display { position: relative; padding: 4px 31px; } .hbspt-form .hs-form-radio-display span, .hbspt-form .hs-form-checkbox-display span { position: relative; cursor: pointer; font-size: 15px; font-weight: 300; } .hbspt-form .hs-input[type=radio] { position: absolute; left: 0; z-index: 2; width: 20px !important; height: 20px !important; outline: none; cursor: pointer; background-color: transparent !important; border-radius: 50%; } .hbspt-form .hs_protocol_synopsis_upload .input{position: relative;} .hbspt-form input[type="file"]::-webkit-file-upload-button { cursor: pointer; background-color: #157479; padding: 10px 20px !important; border: 1px solid #157479; border-top-left-radius: 0px; border-bottom-left-radius: 0px; border-top-right-radius: 6px; border-bottom-right-radius: 6px; color: #fff; position: absolute; top: 0; bottom: 0; right: 0; } .hbspt-form input[type="file"] { cursor: pointer; padding: 10px 20px !important; position: relative; top: 0; bottom: 0; right: 0; } /*Form Responsive CSS*/ @media only screen and (min-width: 1024px) and (max-width: 1366px){ .hs_email, .hs_contact_country { clear: both; } } @media only screen and (min-width: 992px) and (max-width: 1024px){ .hs_email, .hs_contact_country { clear: both; } } @media (min-width: 640px) and (max-width: 1120px) { .hbspt-form h1{font-size: 36px !important;} } @media screen and (min-width: 1120px) { .hbspt-form h1{font-size: 45px !important;margin-bottom: 17px !important;} .hbspt-form .gform_heading p{font-size: 17px !important;} } @media only screen and (min-width: 768px) and (max-width: 992px){ .hs_email, .hs_contact_country{ clear: both; } } @media (min-width: 767px) and (max-width: 1024px) { body .hubspot_signup_form .hs_email{width: 66% !important; float: left !important;} } @media screen and (max-width: 992px){ .assay-kit-hbspt-form .fl-col { width: 100%; } } @media screen and (max-width:812px){ .assay-kit-hbspt-form .fl-col { max-width: 100%; } .hbspt-form .hs-fieldtype-select .input:before{ right: 20px !important; } } @media screen and (max-width: 767px){ .hs_submit .actions{padding-top: 0px !important; margin-top: 0px !important;} body .hbspt-form fieldset.form-columns-2 .input {margin-right: 0px !important;} body fieldset.form-columns-3 .input{margin-right: 0px !important;} .hs-form-field .hs-input { width: 100% !important; } .hs-fieldtype-textarea .input{margin-right: 0px !important;} .hs_firstname, .hs_phone, .hs_development_area{ width: 100% !important; } } @media screen and (min-width: 640px){ .hbspt-form .hs_firstname, .kits_form_col .hs_email{ 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Scientist</a></div></div></div><div class="breadcrumbs"><span><span><a href="https://www.bioagilytix.com/"><i class="home-icon"></i><span class="screen-reader-text">Home</span></a></span> <span class="breadcrumb-separator"></span> <span><a href="https://www.bioagilytix.com/techniques/">Techniques & Platforms</a></span> <span class="breadcrumb-separator"></span> <span><a href="https://www.bioagilytix.com/techniques/instrumentation/">Instrumentation</a></span> <span class="breadcrumb-separator"></span> <span class="breadcrumb_last" aria-current="page">Gyrolab</span></span></div></div></section><div class="wp-block-group alignwide is-layout-constrained wp-container-core-group-is-layout-1 wp-block-group-is-layout-constrained"><p class="has-text-align-center has-large-font-size">BioAgilytix uses the Gyros platform to perform immunoassays using this proprietary microfluidics system. Immunoassays on the Gyrolab generate quick, reproducible results using much smaller sample volumes than traditional ELISA techniques. Gyrolab automates robust immunoassays run with identical microfluidic channels using highly sensitive, laser-induced fluorescence (LIF) detection. <strong> </strong></p></div><div id="block_9528f7215644eebf0d8fded23dc88db8" class="wp-block em-media-content alignfull"><div class="em-media-content__inner em-media-content__inner--media-right has-gray-xxl-background-color em-media-content__inner--content-has-padding"><div class="em-media-content__media em-media-content__media--right"> <img fetchpriority="high" decoding="async" src="https://www.bioagilytix.com/wp-content/uploads/2023/10/shutterstock_2181578479.jpg" alt="Antibody rendering" class="object-fit--cover" srcset="https://www.bioagilytix.com/wp-content/uploads/2023/10/shutterstock_2181578479.jpg 1000w, https://www.bioagilytix.com/wp-content/uploads/2023/10/shutterstock_2181578479-300x141.jpg 300w, https://www.bioagilytix.com/wp-content/uploads/2023/10/shutterstock_2181578479-768x362.jpg 768w, https://www.bioagilytix.com/wp-content/uploads/2023/10/shutterstock_2181578479-100x47.jpg 100w" width="1000" height="471"></div><div class="em-media-content__content em-media-content__content--left em-media-content__content--add-padding"><h2 class="h2"><strong><strong>BioAgilytix’s Gyrolab platform expertise  </strong></strong></h2><p class="">When your immunoassay needs high precision and high throughput, but low sample volumes and tight timelines are complicating factors, BioAgilytix makes Gyrolab our go-to technology. Its flow-through affinity column format minimizes matrix interference while using nanoliter-sized sample volumes. We know how to best leverage the Gyros platform’s unique capabilities to make the most of your precious sample volumes and can quickly develop the assays we need to deliver fast, efficient, and reliable results. Collaborate with our scientific team and we’ll help you determine how the Gyros can best be used to support your program. </p></div></div></div><div id="block_695cff5392c9d3e667abb4b424adfcfa" class="wp-block em-media-content alignwide"><div class="em-media-content__inner em-media-content__inner--media-left has-none-background-color"><div class="em-media-content__media em-media-content__media--left"> <noscript><img decoding="async" src="https://www.bioagilytix.com/wp-content/uploads/2023/07/platform-gyro-ad33.png" alt="gyro platform illustration" class="object-fit--contain" srcset="https://www.bioagilytix.com/wp-content/uploads/2023/07/platform-gyro-ad33.png 389w, https://www.bioagilytix.com/wp-content/uploads/2023/07/platform-gyro-ad33-288x300.png 288w, https://www.bioagilytix.com/wp-content/uploads/2023/07/platform-gyro-ad33-100x104.png 100w" width="389" height="405"></noscript><img decoding="async" src='data:image/svg+xml,%3Csvg%20xmlns=%22http://www.w3.org/2000/svg%22%20viewBox=%220%200%20389%20405%22%3E%3C/svg%3E' data-src="https://www.bioagilytix.com/wp-content/uploads/2023/07/platform-gyro-ad33.png" alt="gyro platform illustration" class="lazyload object-fit--contain" data-srcset="https://www.bioagilytix.com/wp-content/uploads/2023/07/platform-gyro-ad33.png 389w, https://www.bioagilytix.com/wp-content/uploads/2023/07/platform-gyro-ad33-288x300.png 288w, https://www.bioagilytix.com/wp-content/uploads/2023/07/platform-gyro-ad33-100x104.png 100w" width="389" height="405"></div><div class="em-media-content__content em-media-content__content--right"><h2 class="has-primary-l-color has-text-color h6"><strong><strong>Ideal Gyrolab applications: </strong></strong></h2><h2 class="h2 em-mt--xs em-mb--none"><strong><strong>For nanoliter-scale immunoassays </strong></strong></h2><p class="">The flexibility of Gyros’ technology makes it a viable platform for any phase of your drug program. In the discovery stage, development is subject to aggressive timelines, and large and diverse sample numbers must be analyzed — typically with limited sample and reagent volumes. For such projects, Gyrolab enables serial sampling on reduced volumes, with rapid time to results. In comparison, for regulated bioanalysis Gyrolab’s automation increases method robustness and shortens project timelines by yielding high-quality data for fast decision-making. </p><p class="">Overall, the Gyros platform is valuable when used in studies with small sample volumes or microsampling, but which require frequent collections. It’s also used for a range of complex matrices such as CSF or sputum. The BioAgilytix team uses our Gyrolab xP workstations to support our work with biomarkers, pharmacokinetics (PK), and lot release testing, but we have the expertise to tailor the platform to meet your unique assay specifications. </p></div></div></div><div class="wp-block-emagine-background alignfull has-gray-xxl-background-color has-background-dim em-mt--lg"><div class="wp-block-emagine-background__content"><div class="wp-block-emagine-background__content-inner"><div id="block_a6ec0f5410c0c22a8fc94d2904271028" class="wp-block em-media-content em-mt--none em-mb--none alignwide"><div class="em-media-content__inner em-media-content__inner--media-right has-none-background-color em-media-content__inner--content-has-padding"><div class="em-media-content__media em-media-content__media--right"> <noscript><img decoding="async" src="https://www.bioagilytix.com/wp-content/uploads/2023/07/gyrolab-benefits-300x259-1.webp" alt="gyrolab benefit chart" class="object-fit--contain" srcset="https://www.bioagilytix.com/wp-content/uploads/2023/07/gyrolab-benefits-300x259-1.webp 300w, https://www.bioagilytix.com/wp-content/uploads/2023/07/gyrolab-benefits-300x259-1-100x86.webp 100w" width="300" height="259"></noscript><img decoding="async" src='data:image/svg+xml,%3Csvg%20xmlns=%22http://www.w3.org/2000/svg%22%20viewBox=%220%200%20300%20259%22%3E%3C/svg%3E' data-src="https://www.bioagilytix.com/wp-content/uploads/2023/07/gyrolab-benefits-300x259-1.webp" alt="gyrolab benefit chart" class="lazyload object-fit--contain" data-srcset="https://www.bioagilytix.com/wp-content/uploads/2023/07/gyrolab-benefits-300x259-1.webp 300w, https://www.bioagilytix.com/wp-content/uploads/2023/07/gyrolab-benefits-300x259-1-100x86.webp 100w" width="300" height="259"></div><div class="em-media-content__content em-media-content__content--left em-media-content__content--add-padding"><h2 class="has-primary-l-color has-text-color h6 em-mb--none"><strong><strong><strong>Key Gyrolab benefits: </strong></strong></strong></h2><h2 class="h2 em-mt--xs"><strong><strong><strong>high precision and fast total assay time </strong> </strong></strong></h2><p class="">By significantly reducing sample and reagent consumption, Gyrolab removes time- and cost-consuming roadblocks faced with limited sample availability in more traditional methods. The platform’s ability to automate assay workflows eliminates many of the steps where human error can cause variability in assay performance, and yields rapid but accurate results for fast, effective decision-making. The technology behind the Gyros platform also minimizes dilutions and assay repeats by reproducibly measuring concentrations over a broad dynamic range. This simplifies the assay timelines and increases throughput. </p><p class="">There is little need for sample pretreatment, and assays can be run in a diverse range of matrices. This flexibility extends to assay formats as well. Gyrolab CDs provide a foundation on which to design assays to quantify proteins with a suitable antibody binding pair. </p></div></div></div></div></div></div><div id="block_4c8c12d79656789853b68b4e436b7340" class="wp-block em-media-content em-mt--md em-mb--md alignwide"><div class="em-media-content__inner em-media-content__inner--media-left has-none-background-color"><div class="em-media-content__media em-media-content__media--left"> <noscript><img decoding="async" src="https://www.bioagilytix.com/wp-content/uploads/2023/07/gyrolab-1.png" alt="gyrolab device illustration" class="object-fit--contain" srcset="https://www.bioagilytix.com/wp-content/uploads/2023/07/gyrolab-1.png 512w, https://www.bioagilytix.com/wp-content/uploads/2023/07/gyrolab-1-300x300.png 300w, https://www.bioagilytix.com/wp-content/uploads/2023/07/gyrolab-1-150x150.png 150w, https://www.bioagilytix.com/wp-content/uploads/2023/07/gyrolab-1-100x100.png 100w" width="512" height="512"></noscript><img decoding="async" src='data:image/svg+xml,%3Csvg%20xmlns=%22http://www.w3.org/2000/svg%22%20viewBox=%220%200%20512%20512%22%3E%3C/svg%3E' data-src="https://www.bioagilytix.com/wp-content/uploads/2023/07/gyrolab-1.png" alt="gyrolab device illustration" class="lazyload object-fit--contain" data-srcset="https://www.bioagilytix.com/wp-content/uploads/2023/07/gyrolab-1.png 512w, https://www.bioagilytix.com/wp-content/uploads/2023/07/gyrolab-1-300x300.png 300w, https://www.bioagilytix.com/wp-content/uploads/2023/07/gyrolab-1-150x150.png 150w, https://www.bioagilytix.com/wp-content/uploads/2023/07/gyrolab-1-100x100.png 100w" width="512" height="512"></div><div class="em-media-content__content em-media-content__content--right"><h3 class="h3"><strong><strong><strong>How the Gyrolab platform works </strong></strong></strong></h3><p class="">Gyrolab xP uses proprietary Gyrolab CD technology, which is engineered with highly reproducible nanoliter microfluidics for development of robust, nanoliter-scale immunoassays exhibiting broad dynamic ranges. Within each CD itself, a volume definition chamber delivers ultra-accurate sample volumes, with hydrophobic breaks to ensure consistency in volume delivery. An overflow channel eliminates the need for manual pipetting accuracy, and a 15-nL affinity capture column mitigates nonspecific binding. </p><p class="">Once CDs are loaded into the Gyrolab workstation (up to five discs in a series), the platform performs parallel sample processing via highly-sensitive, laser-induced fluorescence detection. The CDs are spun at controlled speeds to ensure optimal binding and uniform conditions for all assays. This is possible through precise, automated control of centrifugal and capillary forces, which directs liquid flow through nanoliter-scale microfluidic structures contained within the CD. </p></div></div></div><div class="wp-block-emagine-grid alignfull wp-block-emagine-grid--halves em-mb--xs"><div class="wp-block-emagine-grid__inner em-grid-2_sm-1-equalHeight-left"><div class="wp-block-emagine-column em-col"><div class="wp-block-emagine-background alignfull has-primary-l-background-color has-background-dim em-pt--md em-pb--md"><div class="wp-block-emagine-background__content"><div class="wp-block-emagine-background__content-inner"><div id="block_902620fdfb0b3aa783336e35401b88b7" class="wp-block em-call-to-action alignfull"><div class="em-call-to-action--align-center has-none-background-color has-background-opacity-- em-pt--md em-pb--md em-pl--md em-pr--md"><div class="em-call-to-action__inner"><p class="">Webinar</p><h2 class="h2">Gyrolab<sup><sup>®</sup></sup>: Case studies in assay development & validation</h2><div class="wp-block-emagine-button has-text-align-left"><a class="btn btn--size-md btn--style-primary has-quaternary-background-color" href="https://go.bioagilytix.com/gyrolab-case-studies-in-assay-development-and-validation-on-demand" target="_blank" rel="noreferrer noopener" aria-label=""><span>Learn <span class="btn__last-word">More</span></span></a></div></div></div></div></div></div></div></div><div class="wp-block-emagine-column em-col"><div class="wp-block-emagine-background alignfull has-primary-l-background-color has-background-dim em-pt--md em-pb--md"><div class="wp-block-emagine-background__content"><div class="wp-block-emagine-background__content-inner"><div id="block_902620fdfb0b3aa783336e35401b88b7" class="wp-block em-call-to-action alignfull"><div class="em-call-to-action--align-center has-none-background-color has-background-opacity-- em-pt--md em-pb--md em-pl--md em-pr--md"><div class="em-call-to-action__inner"><p class="">Webinar</p><h2 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