Reference Citation Analysis: Find an Article, Find a Category, Find a Journal, Find a Scholar

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class="main-part cl"> <div class="main-search-container"> <div class="search-form search-centered"> <div class="search-component-container"> <ul class="ul cl"> <li class="fl"> <table id="FieldItems_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="FieldItems_TL">Loading…</span></td> </tr> </table><div id="FieldItems_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue devex-combobox FieldItems" id="FieldItems"> <tr> <td style="display:none;"><input id="FieldItems_VI" name="FieldItems_VI" type="hidden" value="an" /></td><td class="dxic" 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class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="OpeartorItems_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Contains</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Equals</td> </tr> </table> </div></td> </tr> </table><script id="dxss_597138281" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_24426426" type="text/javascript">  </script><script id="dxss_1793334323" type="text/javascript">  </script> </li> <li id="TermInputContainer" class="fl TermInputContainer"> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue input-text SearchTermText dxeTextBoxDefaultWidthSys" id="SearchTerm"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="SearchTerm_I" name="ctl00$SearchTerm" onfocus="ASPx.EGotFocus('SearchTerm')" onblur="ASPx.ELostFocus('SearchTerm')" onchange="ASPx.EValueChanged('SearchTerm')" value="Teresa Rubio-Tomás" type="text" /></td> </tr> </table><script id="dxss_543298418" type="text/javascript">  </script> <span class="search-icon-container"> <a class="search-icon" href="javascript:openCategorySelector(1);"><img src="/Contents/Images/search.png" /></a> </span> </li> <li class="fl"> <div class="dxbButton_MetropolisBlue SearchButton dxbButtonSys dxbTSys" id="SearchArticle" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="SearchArticle_I" class="dxb-hb" value="Find an Article" type="submit" name="ctl00$SearchArticle" /><span class="dx-vam">Find an Article</span> </div> </div><script id="dxss_842240986" type="text/javascript">  </script> </li> </ul> <div class="cl"></div> <div class="search-menu"> <span>Find an Article (55806887)</span>   <a href="/Categories" target="_blank">Find a Category (125)</a>   <a href="/SearchJournal" target="_blank">Find a Journal (6160)</a>   <a href="/searchscholar" target="_blank">Find a Scholar (3725)</a>   <a href="/searchacademicassistant" target="_blank">Find an Academic Assistant (18)</a> </div> <div class="search-menu" style="text-align:center;"> <span>Find an Article PDF (4648657)</span>   <a href="/TodayArticles" target="_self">Today's Articles (6)</a>   <span>Subscriber (50765)</span> </div> </div> </div> </div> <script src="/bundles/UserAcademicAchievement?v=QYKvd9c2mOpOgKt90go7osO6NdxcNzivChzWAq_gw3g1"></script> <script type="text/javascript"> $(function () { try { var sort = getQueryString2('sort'); if (sort != null && sort != '') { if ($("[field='st" + sort + "']").length) { $("[field='st" + sort + "']").addClass("sort-highlight"); } if ($("#" + sort + "sortedCheck").length) { $("#" + sort + "sortedCheck").prop("checked", true); } } $("a.readmore").click(function () { $(this).parent().toggle().next().toggle(); }); $("a.readless").click(function () { 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LoadingPanel.Show(); var uri = "/api/BpgUser/DeleteFriend?id=" + id; $.ajax({ type: "get", url: uri, async: false }).done(function () { window.location.href = window.location.href; }); } } function SelectAllFriend() { $("input[name='checkfriend']").each(function () { $(this).attr("checked", $('#selectAllFriend').prop("checked")); }); onCheckFriendClick(); } function onCheckFriendClick() { var itemArray = new Array(); $("input[name='checkfriend']:checked").each(function () { itemArray.push($(this).val()); }); if (itemArray.length > 0) { $("#BatchMessageContainer").show(); } else { $("#BatchMessageContainer").hide(); } } function SendBatchMessages() { var itemArray = new Array(); var idArray = new Array(); $("input[name='checkfriend']:checked").each(function () { itemArray.push($(this).val()); idArray.push($(this).attr("data-id")); }); if (itemArray.length > 0) { if (itemArray.length == 1) { OpenMessage(idArray[0], itemArray[0]); } else { var friendIds = JSON.stringify(itemArray); OpenBatchFriendMessage(friendIds); } } } function ImportSingleArticle(doi, controlId) { if (doi != '') { LoadingPanel.Show(); var uri = "/api/BpgUser/ImportArticle?doiPmid=" + encodeURIComponent(doi); $.ajax({ type: "get", url: uri, beforeSend: function (xhr) { LoadingPanel.Show(); } }).done(function (data) { LoadingPanel.Hide(); if (data) { alert("Import Successfully!"); var currentControl = $("#" + controlId); currentControl.parent().hide(); } }).always(function () { LoadingPanel.Hide(); }); } } function ImportAllArticles() { LoadingPanel.Show(); var term = getQueryString2('term'); var uri = "/api/BpgUser/ImportArticlesFromSearch?term=" + term; $.ajax({ type: "get", url: uri, beforeSend: function (xhr) { LoadingPanel.Show(); } }).done(function () { LoadingPanel.Hide(); alert("Imorting is executing!"); }).always(function () { LoadingPanel.Hide(); }); } </script> <input type="hidden" name="ctl00$RootHolder$RCAId" id="RCAId" /> <input type="hidden" name="ctl00$RootHolder$RCAUserType" id="RCAUserType" /> <input type="hidden" name="ctl00$RootHolder$UserId" id="UserId" /> <input type="hidden" name="ctl00$RootHolder$IsCurrentUser" id="IsCurrentUser" /> <div class="search-result-container cl"> <div class="search-centered cl"> <div class="search-result-center-container cl"> <div class="left-part"> <div id="RootHolder_ExportContainer" class="export-container"> <div class="dxbButton_MetropolisBlue DefaultButton-Oral dxbButtonSys dxbTSys" id="RootHolder_DownloadArticle" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_DownloadArticle_I" class="dxb-hb" value="Download" type="button" name="ctl00$RootHolder$DownloadArticle" /><span class="dx-vam">Download</span> </div> </div><script id="dxss_1963926087" type="text/javascript">  </script> </div> <div class="mnavbar"> <table class="total-count-container cl"> <tr> <td> <a href="/" target="_blank" class="white-link">Total Articles</a> </td> </tr> </table> </div> <div class="mnavbox"> <label id="RootHolder_TotalCountText" class="total-count-text">19</label> <br /> <label style="font-size: 14px;">(from Reference Citation Analysis)</label> <div id="RootHolder_SearchArticlePDFContainer" style="padding-top: 1rem;"> <input name="ctl00$RootHolder$ArticlesWithPdf" type="checkbox" id="RootHolder_ArticlesWithPdf" class="ArticlesWithPdf" onclick="SearchArticleWithPDF();" /> <label for="ArticlesWithPdf">Article PDFs (5)</label> </div> <div id="RootHolder_SearchTCContainer" style="padding-top: 1rem;"> <input name="ctl00$RootHolder$ArticlesWithTC" type="checkbox" id="RootHolder_ArticlesWithTC" class="ArticlesWithTC" onclick="SearchArticleWithTC();" /> <label for="ArticlesWithTC">Cited by ≥ 1 (11)</label> </div> </div> <div class="mnavbar" id="SearchedNameTitle"> <div> Searched Name </div> </div> <div class="mnavbox" id="SearchedNameText"> <label id="RootHolder_SearchTermText" class="search-term-text">Teresa Rubio-Tomás</label> </div> <div id="yearFacetContainer"> <div class="mnavbar"> <div> Year Published </div> </div> <div class="mnavbox"> <div id="yearFacetItemContainer"> </div> <div class="refine-btn-container cl"> <a href="javascript:ShowResultItems('year');" class="refine-link-btn" target="_self">Show more</a>   <a href="javascript:SubmitFacetSearch();" class="refine-link-btn refine-link-btn-right" name="refineyearcheck" target="_self">Refine</a> </div> </div> </div> <div id="jsFacetContainer"> <div class="mnavbar"> <div> Article Statistics </div> </div> <div class="mnavbox"> <div id="jsFacetItemContainer"> </div> <div class="refine-btn-container cl" name="refinejscheck"> <a href="javascript:SubmitFacetSearch();" class="refine-link-btn refine-link-btn-right" name="refinejscheck" target="_self">Refine</a> </div> </div> </div> <div class="mnavbar"> <div> Ranked By </div> </div> <div class="mnavbox"> <ul class="ul sortedby-list"> <li> <input type="radio" id="aisortedCheck" onclick="SetSorted('ai')" name="sortedbycheck" value="aisorted" /> <a href="javascript:void(0);" name="sortedby" onclick="SetSorted('ai')" id="aisorted">Impact Index Per Article</a> </li> <li> <input type="radio" id="citedf6sortedCheck" onclick="SetSorted('citedf6')" name="sortedbycheck" value="citedf6sorted" /> <a href="javascript:void(0);" name="sortedby" onclick="SetSorted('citedf6')" id="citedf6sorted"> Citation(s) in <i>RCA</i> </a> </li> </ul> </div> <div id="RootHolder_ResultsAnalysisContainer"> <div class="mnavbar"> <div> Results Analysis </div> </div> <div class="mnavbox"> <ul class="ul analysis-list"> <li> <input type="checkbox" id="YearAnalysis" onclick="InitializeResultAnalysisBtn();" name="analysis-check" value="year" />  <label for="YearAnalysis">Year Published Analysis</label> </li> <li> <input type="checkbox" id="ArticleTypeAnalysis" onclick="InitializeResultAnalysisBtn();" name="analysis-check" value="at" />  <label for="ArticleTypeAnalysis">Article Type Analysis</label> </li> <li> <input type="checkbox" id="JournalTitleAnalysis" onclick="InitializeResultAnalysisBtn();" name="analysis-check" value="journal" />  <label for="JournalTitleAnalysis">Publication Title Analysis</label> </li> <li> <input type="checkbox" id="CategoriesAnalysis" onclick="InitializeResultAnalysisBtn();" name="analysis-check" value="subject" />  <label for="CategoriesAnalysis">Category Analysis</label> </li> </ul> <div class="refine-btn-container cl" name="analysis-check-btn-container"> <a href="javascript:ResultAnalysis();" class="refine-link-btn refine-link-btn-right" target="_self">Results Analysis</a> </div> </div> </div> <div class="refine-btn-container-n cl" id="showFacetsContainer"> <a href="javascript:InitAllFacets();" class="refine-link-btn-right" target="_self">Show more</a> </div> <div id="facetsContainer" class="cl" style="display: none;"> <div class="mnavbar" id="PubDateFacetTitle"> <div> Indexed Articles </div> </div> <div class="mnavbox" id="PubDateFacetContainer"> <ul class="ul 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class="refine-link-btn" target="_self">Show more</a>   <a href="javascript:SubmitFacetSearch();" class="refine-link-btn refine-link-btn-right" name="refinejournalcheck" target="_self">Refine</a> </div> </div> </div> <div id="fundFacetContainer"> <div class="mnavbar"> <div> Grant Agencies </div> </div> <div class="mnavbox"> <div id="fundFacetItemContainer"> </div> <div class="refine-btn-container cl"> <a href="javascript:ShowResultItems('fund');" class="refine-link-btn" target="_self">Show more</a>   <a href="javascript:SubmitFacetSearch();" class="refine-link-btn refine-link-btn-right" name="refinefundcheck" target="_self">Refine</a> </div> </div> </div> <div id="subjectFacetContainer"> <div class="mnavbar"> <div> Category </div> </div> <div class="mnavbox"> <div id="subjectFacetItemContainer"> </div> <div class="refine-btn-container cl"> <a href="javascript:ShowResultItems('subject');" class="refine-link-btn" target="_self">Show more</a>   <a href="javascript:SubmitFacetSearch();" class="refine-link-btn refine-link-btn-right" name="refinesubjectcheck" target="_self">Refine</a> </div> </div> </div> </div> </div> <div class="right-part"> <div class="mnavbar" style="margin-bottom: 0.625rem;"> <div> Journal Articles </div> </div> <table class="article-result-list cl"> <thead> <tr> <td> <span class="dxeBase_MetropolisBlue" id="RootHolder_SearchResultList_NumberTitle">Number</span> </td> <td> <span class="dxeBase_MetropolisBlue" id="RootHolder_SearchResultList_NameTitle">Citation Analysis</span> </td> </tr> </thead> <tbody> <tr id="articlerow1"> <td style="min-width: 40px; text-align: center;"> 1 </td> <td> <div id="citation1" class="article-citation"> <b>Kalykaki M</b>, Rubio-Tomás T, Tavernarakis N. The role of mitochondria in cytokine and chemokine signalling during ageing. <em class='incite-journal-name' onclick='ShowInCiteJournal(16534);'>Mech Ageing Dev</em> 2024;<b>222</b>:111993. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39307464' target='_blank'>39307464</a> DOI: <a href='https://dx.doi.org/10.1016/j.mad.2024.111993' target='_blank'>10.1016/j.mad.2024.111993</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.mad.2024.111993','39307464', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(1);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(1);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.mad.2024.111993' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(16534);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/01/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/15/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/17/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/28/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv1" value="10.1016/j.mad.2024.111993" /> <div style="display: none" id="articleAbstract1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Ageing is accompanied by a persistent, low-level inflammation, termed "inflammageing", which contributes to the pathogenesis of age-related diseases. Mitochondria fulfil multiple roles in host immune responses, while mitochondrial dysfunction, a hallmark of ageing, has been shown to promote chronic inflammatory states by regulating the production of cytokines and chemokines. In this review, we aim to disentangle the molecular mechanisms underlying this process. We describe the role of mitochondrial signalling components such as mitochondrial DNA, mitochondrial RNA, N-formylated peptides, ROS, cardiolipin, cytochrome c, mitochondrial metabolites, potassium efflux and mitochondrial calcium in the age-related immune system activation. Furthermore, we discuss the effect of age-related decline in mitochondrial quality control mechanisms, including mitochondrial biogenesis, dynamics, mitophagy and UPRmt, in inflammatory states upon ageing. In addition, we focus on the dynamic relationship between mitochondrial dysfunction and cellular senescence and its role in regulating the secretion of pro-inflammatory molecules by senescent cells. Finally, we review the existing literature regarding mitochondrial dysfunction and inflammation in specific age-related pathological conditions, including neurodegenerative diseases (Alzheimer's and Parkinson's disease, and amyotrophic lateral sclerosis), osteoarthritis and sarcopenia. </div> <a href="javascript:ShowArticleAbstract(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Age-related+disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Age-related disease</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chemokine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chemokine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cytokine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cytokine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammageing%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammageing</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mitochondrial+dysfunction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mitochondrial dysfunction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Senescence%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Senescence</a></li></ul> <a href="javascript:ShowArticleKeywords(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(1);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow2"> <td style="min-width: 40px; text-align: center;"> 2 </td> <td> <div id="citation2" class="article-citation"> <b>Amaro-da-Cruz A</b>, Rubio-Tomás T, Álvarez-Mercado AI. Specific microbiome patterns and their association with breast cancer: the intestinal microbiota as a potential biomarker and therapeutic strategy. <em class='incite-journal-name' onclick='ShowInCiteJournal(168492);'>Clin Transl Oncol</em> 2024:10.1007/s12094-024-03554-w. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38890244' target='_blank'>38890244</a> DOI: <a href='https://dx.doi.org/10.1007/s12094-024-03554-w' target='_blank'>10.1007/s12094-024-03554-w</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s12094-024-03554-w','38890244', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(2);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(2);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s12094-024-03554-w' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(168492);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 03/13/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 06/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 06/20/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv2" value="10.1007/s12094-024-03554-w" /> <div style="display: none" id="articleAbstract2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Breast cancer (BC) is one of the most diagnosed cancers in women. Based on histological characteristics, they are classified as non-invasive, or in situ (tumors located within the milk ducts or milk lobules) and invasive. BC may develop from in situ carcinomas over time. Determining prognosis and predicting response to treatment are essential tools to manage this disease and reduce its incidence and mortality, as well as to promote personalized therapy for patients. However, over half of the cases are not associated with known risk factors. In addition, some patients develop resistance to treatment and relapse. Therefore, it is necessary to identify new biomarkers and treatment strategies that improve existing therapies. In this regard, the role of the microbiome is being researched as it could play a role in carcinogenesis and the efficacy of BC therapies. This review aims to describe specific microbiome patterns associated with BC. For this, a literature search was carried out in PubMed database using the MeSH terms "Breast Neoplasms" and "Gastrointestinal Microbiome", including 29 publications. Most of the studies have focused on characterizing the gut or breast tissue microbiome of the patients. Likewise, studies in animal models and in vitro that investigated the impact of gut microbiota (GM) on BC treatments and the effects of the microbiome on tumor cells were included. Based on the results of the included articles, BC could be associated with an imbalance in the GM. This imbalance varied depending on molecular type, stage and grade of cancer, menopause, menarche, body mass index, and physical activity. However, a specific microbial profile could not be identified as a biomarker. On the other hand, some studies suggest that the GM may influence the efficacy of BC therapies. In addition, some microorganisms and bacterial metabolites could improve the effects of therapies or influence tumor development. </div> <a href="javascript:ShowArticleAbstract(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Biomarkers%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Biomarkers</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Breast+cancer%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Breast cancer</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chemotherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chemotherapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Microbiome%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Microbiome</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Microbiota%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Microbiota</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Therapy</a></li></ul> <a href="javascript:ShowArticleKeywords(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(2);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow3"> <td style="min-width: 40px; text-align: center;"> 3 </td> <td> <div id="citation3" class="article-citation"> <b>Rubio-Tomás T</b>, Soler-Botija C, Martínez-Estrada O, Villena JA. Transcriptional control of cardiac energy metabolism in health and disease: Lessons from animal models. <em class='incite-journal-name' onclick='ShowInCiteJournal(3279);'>Biochem Pharmacol</em> 2024;<b>224</b>:116185. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38561091' target='_blank'>38561091</a> DOI: <a href='https://dx.doi.org/10.1016/j.bcp.2024.116185' target='_blank'>10.1016/j.bcp.2024.116185</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bcp.2024.116185','38561091', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(3);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(3);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(3);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bcp.2024.116185' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3279);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 12/11/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 02/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 03/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 04/04/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv3" value="10.1016/j.bcp.2024.116185" /> <div style="display: none" id="articleAbstract3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Cardiac ATP production is tightly regulated in order to satisfy the evolving energetic requirements imposed by different cues during health and pathological conditions. In order to sustain high ATP production rates, cardiac cells are endowed with a vast mitochondrial network that is essentially acquired during the perinatal period. Nevertheless, adult cardiac cells also adapt their mitochondrial mass and oxidative function to changes in energy demand and substrate availability by fine-tuning the pathways and mitochondrial machinery involved in energy production. The reliance of cardiac cells on mitochondrial metabolism makes them particularly sensitive to alterations in proper mitochondrial function, so that deficiency in energy production underlies or precipitates the development of heart diseases. Mitochondrial biogenesis is a complex process fundamentally controlled at the transcriptional level by a network of transcription factors and co-regulators, sometimes with partially redundant functions, that ensure adequate energy supply to the working heart. Novel uncovered regulators, such as RIP140, PERM1, MED1 or BRD4 have been recently shown to modulate or facilitate the transcriptional activity of the PGC-1s/ERRs/PPARs regulatory axis, allowing cardiomyocytes to adapt to a variety of physiological or pathological situations requiring different energy provision. In this review, we summarize the current knowledge on the mechanisms that regulate cardiac mitochondrial biogenesis, highlighting the recent discoveries of new transcriptional regulators and describing the experimental models that have provided solid evidence of the relevant contribution of these factors to cardiac function in health and disease. </div> <a href="javascript:ShowArticleAbstract(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cardiac+disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cardiac disease</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diabetic+cardiomyopathy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diabetic cardiomyopathy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heart%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heart</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mitochondria%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mitochondria</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Oxidative+metabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Oxidative metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Transcriptional+regulation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Transcriptional regulation</a></li></ul> <a href="javascript:ShowArticleKeywords(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Energy+Metabolism%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Energy Metabolism/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Energy+Metabolism%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Energy Metabolism/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Transcription%2c+Genetic%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Transcription, Genetic/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mitochondria%2c+Heart%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mitochondria, Heart/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mitochondria%2c+Heart%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mitochondria, Heart/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heart+Diseases%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heart Diseases/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heart+Diseases%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heart Diseases/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Myocardium%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Myocardium/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Regulation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Regulation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Transcription+Factors%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Transcription Factors/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Transcription+Factors%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Transcription Factors/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Myocytes%2c+Cardiac%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Myocytes, Cardiac/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(3);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow4"> <td style="min-width: 40px; text-align: center;"> 4 </td> <td> <div id="citation4" class="article-citation"> <b>Rubio-Tomás T</b>, Alegre-Cortés E, Lionaki E, Fuentes JM, Tavernarakis N. Heat shock and thermotolerance in Caenorhabditis elegans: An overview of laboratory techniques. <em class='incite-journal-name' onclick='ShowInCiteJournal(16787);'>Methods Cell Biol</em> 2024;<b>185</b>:1-17. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38556443' target='_blank'>38556443</a> DOI: <a href='https://dx.doi.org/10.1016/bs.mcb.2024.02.001' target='_blank'>10.1016/bs.mcb.2024.02.001</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/bs.mcb.2024.02.001','38556443', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(4);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(4);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(4);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/bs.mcb.2024.02.001' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(16787);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 04/02/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv4" value="10.1016/bs.mcb.2024.02.001" /> <div style="display: none" id="articleAbstract4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The soil nematode worm Caenorhabditis elegans is a simple and well-established model for the study of many biological processes. Heat shock and thermotolerance assays have been developed for this nematode, and have been used to decipher the molecular relationships between thermal stress and aging, among others. Nevertheless, a systematic and methodological comparison of the different approaches and tools utilized is lacking in the literature. Here, we aim to provide a comprehensive summary of the most commonly used strategies for carrying out heat shock and thermotolerance assays that have been reported, highlighting specific readouts and scientific questions that can be addressed. Furthermore, we offer examples of thermotolerance assays performed with wild type nematodes, that can serve as a gauge of the animal survival under diverse conditions of stress. </div> <a href="javascript:ShowArticleAbstract(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Caenorhabditis+elegans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Caenorhabditis elegans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heat+shock%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heat shock</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heat+stroke%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heat stroke</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Necrosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Necrosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neurodegeneration%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neurodegeneration</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thermotolerance%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thermotolerance</a></li></ul> <a href="javascript:ShowArticleKeywords(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Caenorhabditis+elegans%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Caenorhabditis elegans/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Caenorhabditis+elegans+Proteins%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Caenorhabditis elegans Proteins</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heat-Shock+Response%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heat-Shock Response</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thermotolerance%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thermotolerance</a></li></ul> <a href="javascript:ShowArticleMeSH(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(4);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow5"> <td style="min-width: 40px; text-align: center;"> 5 </td> <td> <div id="citation5" class="article-citation"> <b>Jiménez DJ</b>, Javed A, Rubio-Tomás T, Seye-Loum N, Barceló C. Clinical and Preclinical Targeting of Oncogenic Pathways in PDAC: Targeted Therapeutic Approaches for the Deadliest Cancer. <em class='incite-journal-name' onclick='ShowInCiteJournal(11724);'>Int J Mol Sci</em> 2024;<b>25</b>:2860. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38474109' target='_blank'>38474109</a> DOI: <a href='https://dx.doi.org/10.3390/ijms25052860' target='_blank'>10.3390/ijms25052860</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.3390/ijms25052860','38474109', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(5);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(5);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(5);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.3390/ijms25052860' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(11724);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 12/21/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 01/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 01/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 03/14/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv5" value="10.3390/ijms25052860" /> <div style="display: none" id="articleAbstract5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer-related death worldwide. It is commonly diagnosed in advanced stages and therapeutic interventions are typically constrained to systemic chemotherapy, which yields only modest clinical outcomes. In this review, we examine recent developments in targeted therapy tailored to address distinct molecular pathway alteration required for PDAC. Our review delineates the principal signaling pathways and molecular mechanisms implicated in the initiation and progression of PDAC. Subsequently, we provide an overview of prevailing guidelines, ongoing investigations, and prospective research trajectories related to targeted therapeutic interventions, drawing insights from randomized clinical trials and other pertinent studies. This review focus on a comprehensive examination of preclinical and clinical data substantiating the efficacy of these therapeutic modalities, emphasizing the potential of combinatorial regimens and novel therapies to enhance the quality of life for individuals afflicted with PDAC. Lastly, the review delves into the contemporary application and ongoing research endeavors concerning targeted therapy for PDAC. This synthesis serves to bridge the molecular elucidation of PDAC with its clinical implications, the evolution of innovative therapeutic strategies, and the changing landscape of treatment approaches. </div> <a href="javascript:ShowArticleAbstract(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22PDAC%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">PDAC</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22clinical%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">clinical</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22clinical+trials%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">clinical trials</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22combinational+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">combinational therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22molecular+alterations%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">molecular alterations</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22oncogenic+pathways%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">oncogenic pathways</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22preclinical%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">preclinical</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22targeted+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">targeted therapy</a></li></ul> <a href="javascript:ShowArticleKeywords(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Instituto+de+Salud+Carlos+III%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">PI20/01267 and MS19/00100 Instituto de Salud Carlos III</a></li></ul> <a href="javascript:ShowArticleGrant(5);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow6"> <td style="min-width: 40px; text-align: center;"> 6 </td> <td> <div id="citation6" class="article-citation"> <b>Rubio-Tomás T</b>, Sotiriou A, Tavernarakis N. The interplay between selective types of (macro)autophagy: Mitophagy and xenophagy. <em>INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY</em> 2023;<b>374</b>:129-157. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/36858654' target='_blank'>36858654</a> DOI: <a href='https://dx.doi.org/10.1016/bs.ircmb.2022.10.003' target='_blank'>10.1016/bs.ircmb.2022.10.003</a>]<span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.referencecitationanalysis.com/citearticles?term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22c%22%2c%22o%22%3anull%2c%22v%22%3a%2210.1016%2fbs.ircmb.2022.10.003%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d' target='_blank'>Citation(s) in <i>RCA</i>: 3</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInflu('10.1016%2fbs.ircmb.2022.10.003')">Impact Index Per Article: 3.0</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/bs.ircmb.2022.10.003','36858654', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(6);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(6);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/bs.ircmb.2022.10.003' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/27/2022]</span></span> </div> <input type="hidden" name="doiv" id="doiv6" value="10.1016/bs.ircmb.2022.10.003" /> <div style="display: none" id="articleAbstract6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Autophagy is a physiological response, activated by a myriad of endogenous and exogenous cues, including DNA damage, perturbation of proteostasis, depletion of nutrients or oxygen and pathogen infection. Upon sensing those stimuli, cells employ multiple non-selective and selective autophagy pathways to promote fitness and survival. Importantly, there are a variety of selective types of autophagy. In this review we will focus on autophagy of bacteria (xenophagy) and autophagy of mitochondria (mitophagy). We provide a brief introduction to bulk autophagy, as well as xenophagy and mitophagy, highlighting their common molecular factors. We also describe the role of xenophagy and mitophagy in the detection and elimination of pathogens by the immune system and the adaptive mechanisms that some pathogens have developed through evolution to escape the host autophagic response. Finally, we summarize the recent articles (from the last five years) linking bulk autophagy with xenophagy and/or mitophagy in the context on developmental biology, cancer and metabolism.</div> <a href="javascript:ShowArticleAbstract(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22(Macro)autophagy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">(Macro)autophagy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cancer%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cancer</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Development%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Development</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Metabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mitophagy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mitophagy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pathogens%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pathogens</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Xenophagy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Xenophagy</a></li></ul> <a href="javascript:ShowArticleKeywords(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(6);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow7"> <td style="min-width: 40px; text-align: center;"> 7 </td> <td> <div id="citation7" class="article-citation"> <b>Javed A</b>, Yarmohammadi M, Korkmaz KS, Rubio-Tomás T. The Regulation of Cyclins and Cyclin-Dependent Kinases in the Development of Gastric Cancer. <em class='incite-journal-name' onclick='ShowInCiteJournal(11724);'>Int J Mol Sci</em> 2023;<b>24</b>:2848. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/36769170' target='_blank'>36769170</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917736' target='_blank'>PMC9917736</a> DOI: <a href='https://dx.doi.org/10.3390/ijms24032848' target='_blank'>10.3390/ijms24032848</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.3390/ijms24032848','36769170', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(7);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(7);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(7);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.3390/ijms24032848' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="openf" onclick="OpenFigures('10.3390/ijms24032848');">Figures</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(11724);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 12/25/2022]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 01/23/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 01/28/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 02/05/2023]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv7" value="10.3390/ijms24032848" /> <div style="display: none" id="articleAbstract7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Gastric cancer predominantly occurs in adenocarcinoma form and is characterized by uncontrolled growth and metastases of gastric epithelial cells. The growth of gastric cells is regulated by the action of several major cell cycle regulators including Cyclins and Cyclin-dependent kinases (CDKs), which act sequentially to modulate the life cycle of a living cell. It has been reported that inadequate or over-activity of these molecules leads to disturbances in cell cycle dynamics, which consequently results in gastric cancer development. Manny studies have reported the key roles of Cyclins and CDKs in the development and progression of the disease in either in vitro cell culture studies or in vivo models. We aimed to compile the evidence of molecules acting as regulators of both Cyclins and CDKs, i.e., upstream regulators either activating or inhibiting Cyclins and CDKs. The review entails an introduction to gastric cancer, along with an overview of the involvement of cell cycle regulation and focused on the regulation of various Cyclins and CDKs in gastric cancer. It can act as an extensive resource for developing new hypotheses for future studies. </div> <a href="javascript:ShowArticleAbstract(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cyclin-dependent+kinases+(CDKs)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cyclin-dependent kinases (CDKs)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cyclins%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cyclins</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cell+cycle+regulation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cell cycle regulation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cell+signaling%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cell signaling</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22gastric+cancer%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">gastric cancer</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22kinases%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">kinases</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22molecular+oncology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">molecular oncology</a></li></ul> <a href="javascript:ShowArticleKeywords(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cyclin-Dependent+Kinases%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cyclin-Dependent Kinases/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cyclins%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cyclins/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cyclins%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cyclins/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stomach+Neoplasms%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stomach Neoplasms</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Cycle%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Cycle</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Division%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Division</a></li></ul> <a href="javascript:ShowArticleMeSH(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(7);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow8"> <td style="min-width: 40px; text-align: center;"> 8 </td> <td> <div id="citation8" class="article-citation"> <b>Perelló-Reus CM</b>, Rubio-Tomás T, Cisneros-Barroso E, Ibargüen-González L, Segura-Sampedro JJ, Morales-Soriano R, Barceló C. Challenges in precision medicine in pancreatic cancer: A focus in cancer stem cells and microbiota. <em class='incite-journal-name' onclick='ShowInCiteJournal(9356);'>Front Oncol</em> 2022;<b>12</b>:995357. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/36531066' target='_blank'>36531066</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751445' target='_blank'>PMC9751445</a> DOI: <a href='https://dx.doi.org/10.3389/fonc.2022.995357' target='_blank'>10.3389/fonc.2022.995357</a>]<span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.referencecitationanalysis.com/citearticles?term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22c%22%2c%22o%22%3anull%2c%22v%22%3a%2210.3389%2ffonc.2022.995357%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d' target='_blank'>Citation(s) in <i>RCA</i>: 3</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInflu('10.3389%2ffonc.2022.995357')">Impact Index Per Article: 1.5</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.3389/fonc.2022.995357','36531066', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(8);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(8);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.3389/fonc.2022.995357' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="openf" onclick="OpenFigures('10.3389/fonc.2022.995357');">Figures</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(9356);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/15/2022]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/15/2022]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 12/03/2022]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv8" value="10.3389/fonc.2022.995357" /> <div style="display: none" id="articleAbstract8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Pancreatic cancer adenocarcinoma (PDAC) is a lethal disease, with the lowest 5-years survival rate of all cancers due to late diagnosis. Despite the advance and success of precision oncology in gastrointestinal cancers, the frequency of molecular-informed therapy decisions in PDAC is currently neglectable. The reasons for this dismal situation are mainly the absence of effective early diagnostic biomarkers and therapy resistance. PDAC cancer stem cells (PDAC-SC), which are regarded as essential for tumor initiation, relapse and drug resistance, are highly dependent on their niche <i>i.e.</i> microanatomical structures of the tumor microenvironment. There is an altered microbiome in PDAC patients embedded within the highly desmoplastic tumor microenvironment, which is known to determine therapeutic responses and affecting survival in PDAC patients. We consider that understanding the communication network that exists between the microbiome and the PDAC-SC niche by co-culture of patient-derived organoids (PDOs) with TME microbiota would recapitulate the complexity of PDAC paving the way towards a precision oncology treatment-response prediction.</div> <a href="javascript:ShowArticleAbstract(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22PDAC%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">PDAC</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cancer+stem+cell%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cancer stem cell</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22early+diagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">early diagnosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22microbiota%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">microbiota</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22niche+factors%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">niche factors</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22organoid+co-culture%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">organoid co-culture</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22precision+medicine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">precision medicine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22therapy+resistance%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">therapy resistance</a></li></ul> <a href="javascript:ShowArticleKeywords(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(8);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow9"> <td style="min-width: 40px; text-align: center;"> 9 </td> <td> <div id="citation9" class="article-citation"> <b>Rubio-Tomás T</b>, Skouroliakou M, Ntountaniotis D. Lockdown Due to COVID-19 and Its Consequences on Diet, Physical Activity, Lifestyle, and Other Aspects of Daily Life Worldwide: A Narrative Review. <em>INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH</em> 2022;<b>19</b>:6832. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/35682411' target='_blank'>35682411</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180681' target='_blank'>PMC9180681</a> DOI: <a href='https://dx.doi.org/10.3390/ijerph19116832' target='_blank'>10.3390/ijerph19116832</a>]<span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.referencecitationanalysis.com/citearticles?term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22c%22%2c%22o%22%3anull%2c%22v%22%3a%2210.3390%2fijerph19116832%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d' target='_blank'>Citation(s) in <i>RCA</i>: 15</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInflu('10.3390%2fijerph19116832')">Impact Index Per Article: 7.5</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.3390/ijerph19116832','35682411', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(9);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(9);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(9);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.3390/ijerph19116832' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://rcastoragev2.blob.core.windows.net/84d0a78ea10308e25650120aeea440d3/PMC9180681.pdf' target='_blank'>Download PDF</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="openf" onclick="OpenFigures('10.3390/ijerph19116832');">Figures</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 04/08/2022]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 05/21/2022]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 05/24/2022]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 12/23/2022]</span></span> </div> <input type="hidden" name="doiv" id="doiv9" value="10.3390/ijerph19116832" /> <div style="display: none" id="articleAbstract9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The novel coronavirus, termed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is responsible for the disease called coronavirus disease 2019 (COVID-19). Besides the important rates of mortality and morbidity directly attributed to the infection itself, many studies detected an important shift towards mostly unhealthy lifestyle patterns in previously healthy non-infected populations all around the world. Although most of the changes in lifestyle had or will have a negative impact on general population health status, some findings are encouraging. Notwithstanding that there was an obvious necessity for governments to apply national lockdowns, it is also necessary to identify and comprehend the consequences they have caused. A narrative literature review was performed, based on scientific articles and previous reviews. An accurate description of changes in eating habits and alcohol consumption, physical activity, mental health, daily routines, economic impacts, and broader effects on society is provided for each continent and different age groups through this review. The volume of selected scientific surveys encompasses approximately 400,000 persons. </div> <a href="javascript:ShowArticleAbstract(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22COVID-19%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">COVID-19</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22diet%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">diet</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22lifestyle%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">lifestyle</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22lockdown%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">lockdown</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22pandemics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">pandemics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22physical+activity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">physical activity</a></li></ul> <a href="javascript:ShowArticleKeywords(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22COVID-19%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">COVID-19/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Communicable+Disease+Control%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Communicable Disease Control</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diet%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diet</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Exercise%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Exercise</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Life+Style%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Life Style</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22SARS-CoV-2%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SARS-CoV-2</a></li></ul> <a href="javascript:ShowArticleMeSH(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(9);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow10"> <td style="min-width: 40px; text-align: center;"> 10 </td> <td> <div id="citation10" class="article-citation"> <b>Graupera I</b>, Isus L, Coll M, Pose E, Díaz A, Vallverdú J, Rubio-Tomás T, Martínez-Sánchez C, Huelin P, Llopis M, Solé C, Fondevila C, Lozano JJ, Sancho-Bru P, Ginès P, Aloy P. Molecular characterization of chronic liver disease dynamics: from liver fibrosis to acute-on-chronic liver failure. <em class='incite-journal-name' onclick='ShowInCiteJournal(166443);'>JHEP Rep</em> 2022;<b>4</b>:100482. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/35540106' target='_blank'>35540106</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079303' target='_blank'>PMC9079303</a> DOI: <a href='https://dx.doi.org/10.1016/j.jhepr.2022.100482' target='_blank'>10.1016/j.jhepr.2022.100482</a>]<span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.referencecitationanalysis.com/citearticles?term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22c%22%2c%22o%22%3anull%2c%22v%22%3a%2210.1016%2fj.jhepr.2022.100482%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d' target='_blank'>Citation(s) in <i>RCA</i>: 9</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInflu('10.1016%2fj.jhepr.2022.100482')">Impact Index Per Article: 4.5</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.jhepr.2022.100482','35540106', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(10);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.jhepr.2022.100482' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://rcastoragev2.blob.core.windows.net/9f2d350e226c0786f6b75a635203e083/PMC9079303.pdf' target='_blank'>Download PDF</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="openf" onclick="OpenFigures('10.1016/j.jhepr.2022.100482');">Figures</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(166443);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/jhepr/default1.aspx' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 10/01/2021]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 02/22/2022]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 03/15/2022]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/28/2022]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv10" value="10.1016/j.jhepr.2022.100482" /> <div style="display: none" id="articleAbstract10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">Background & Aims</div><p>The molecular mechanisms driving the progression from early-chronic liver disease (CLD) to cirrhosis and, finally, acute-on-chronic liver failure (ACLF) are largely unknown. Our aim was to develop a protein network-based approach to investigate molecular pathways driving progression from early-CLD to ACLF.</p><div class="abstract-label">Methods</div><p>Transcriptome analysis was performed on liver biopsies from patients at different liver disease stages, including fibrosis, compensated cirrhosis, decompensated cirrhosis and ACLF, and control healthy livers. We created 9 liver-specific disease-related protein-protein interaction networks capturing key pathophysiological processes potentially related to CLD. We used these networks as a framework and performed gene set-enrichment analysis (GSEA) to identify dynamic gene profiles of disease progression.</p><div class="abstract-label">Results</div><p>Principal component analyses revealed that samples clustered according to the disease stage. GSEA of the defined processes showed an upregulation of inflammation, fibrosis and apoptosis networks throughout disease progression. Interestingly, we did not find significant gene expression differences between compensated and decompensated cirrhosis, while ACLF showed acute expression changes in all the defined liver disease-related networks. The analyses of disease progression patterns identified ascending and descending expression profiles associated with ACLF onset. Functional analyses showed that ascending profiles were associated with inflammation, fibrosis, apoptosis, senescence and carcinogenesis networks, while descending profiles were mainly related to oxidative stress and genetic factors. We confirmed by qPCR the upregulation of genes of the ascending profile and validated our findings in an independent patient cohort.</p><div class="abstract-label">Conclusion</div><p>ACLF is characterized by a specific hepatic gene expression pattern related to inflammation, fibrosis, apoptosis, senescence and carcinogenesis. Moreover, the observed profile is significantly different from that of compensated and decompensated cirrhosis, supporting the hypothesis that ACLF should be considered a distinct entity.</p><div class="abstract-label">Lay summary</div><p>By using transjugular biopsies obtained from patients at different stages of chronic liver disease, we unveil the molecular pathogenic mechanisms implicated in the progression of chronic liver disease to cirrhosis and acute-on-chronic liver failure. The most relevant finding in this study is that patients with acute-on-chronic liver failure present a specific hepatic gene expression pattern distinct from that of patients at earlier disease stages. This gene expression pattern is mostly related to inflammation, fibrosis, angiogenesis, and senescence and apoptosis pathways in the liver.</p><p><list list-type="simple" id="ulist0010"><list-item id="u0010"><label>•</label><p id="p0010">We unveiled the molecular pathogenic mechanisms implicated in the progression of chronic liver disease to cirrhosis and ACLF.</p></list-item><list-item id="u0015"><label>•</label><p id="p0015">ACLF presents a specific hepatic gene expression pattern distinct from that of patients at earlier disease stages.</p></list-item><list-item id="u0020"><label>•</label><p id="p0020">Gene expression pattern of ACLF is mostly related to inflammation, fibrosis, angiogenesis, senescence and apoptosis pathways in the liver.</p></list-item></list></p> <a href="javascript:ShowArticleAbstract(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <a href="javascript:ShowArticleKeywords(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(10);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow11"> <td style="min-width: 40px; text-align: center;"> 11 </td> <td> <div id="citation11" class="article-citation"> <b>Malagraba G</b>, Yarmohammadi M, Javed A, Barceló C, Rubio-Tomás T. The Role of LSD1 and LSD2 in Cancers of the Gastrointestinal System: An Update. <em class='incite-journal-name' onclick='ShowInCiteJournal(3676);'>Biomolecules</em> 2022;<b>12</b>:462. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/35327654' target='_blank'>35327654</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946813' target='_blank'>PMC8946813</a> DOI: <a href='https://dx.doi.org/10.3390/biom12030462' target='_blank'>10.3390/biom12030462</a>]<span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.referencecitationanalysis.com/citearticles?term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22c%22%2c%22o%22%3anull%2c%22v%22%3a%2210.3390%2fbiom12030462%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d' target='_blank'>Citation(s) in <i>RCA</i>: 14</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInflu('10.3390%2fbiom12030462')">Impact Index Per Article: 7.0</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.3390/biom12030462','35327654', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(11);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(11);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(11);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.3390/biom12030462' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://rcastoragev2.blob.core.windows.net/e25e9974148068227b3a5ae8e473174c/PMC8946813.pdf' target='_blank'>Download PDF</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="openf" onclick="OpenFigures('10.3390/biom12030462');">Figures</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3676);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 02/21/2022]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 03/11/2022]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 03/15/2022]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 02/07/2023]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv11" value="10.3390/biom12030462" /> <div style="display: none" id="articleAbstract11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Epigenetic mechanisms are known to play a key role in cancer progression. Specifically, histone methylation involves reversible post-translational modification of histones that govern chromatin structure remodelling, genomic imprinting, gene expression, DNA damage repair, and meiotic crossover recombination, among other chromatin-based activities. Demethylases are enzymes that catalyse the demethylation of their substrate using a flavin adenine dinucleotide-dependent amine oxidation process. Lysine-specific demethylase 1 (LSD1) and its homolog, lysine-specific demethylase 2 (LSD2), are overexpressed in a variety of human cancer types and, thus, regulate tumour progression. In this review, we focus on the literature from the last 5 years concerning the role of LSD1 and LSD2 in the main gastrointestinal cancers (i.e., gastric cancer, liver cancer, pancreatic cancer, and colorectal cancer). </div> <a href="javascript:ShowArticleAbstract(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22LSD1%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">LSD1</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22LSD2%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">LSD2</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22colorectal+cancer%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">colorectal cancer</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22demethylation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">demethylation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22gastric+cancer%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">gastric cancer</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22liver+cancer%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">liver cancer</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22pancreatic+cancer%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">pancreatic cancer</a></li></ul> <a href="javascript:ShowArticleKeywords(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chromatin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chromatin</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Histone+Demethylases%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Histone Demethylases/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Histone+Demethylases%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Histone Demethylases/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Histones%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Histones/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Lysine%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Lysine/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neoplasms%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neoplasms/genetics</a></li></ul> <a href="javascript:ShowArticleMeSH(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(11);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow12"> <td style="min-width: 40px; text-align: center;"> 12 </td> <td> <div id="citation12" class="article-citation"> <b>Coll M</b>, Ariño S, Mártinez-Sánchez C, Garcia-Pras E, Gallego J, Moles A, Aguilar-Bravo B, Blaya D, Vallverdú J, Rubio-Tomás T, Lozano JJ, Pose E, Graupera I, Fernández-Vidal A, Pol A, Bataller R, Geng JG, Ginès P, Fernandez M, Sancho-Bru P. Ductular reaction promotes intrahepatic angiogenesis through Slit2-Roundabout 1 signaling. <em class='incite-journal-name' onclick='ShowInCiteJournal(10337);'>Hepatology</em> 2022;<b>75</b>:353-368. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/34490644' target='_blank'>34490644</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766889' target='_blank'>PMC8766889</a> DOI: <a href='https://dx.doi.org/10.1002/hep.32140' target='_blank'>10.1002/hep.32140</a>]<span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.referencecitationanalysis.com/citearticles?term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22c%22%2c%22o%22%3anull%2c%22v%22%3a%2210.1002%2fhep.32140%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d' target='_blank'>Citation(s) in <i>RCA</i>: 19</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInflu('10.1002%2fhep.32140')">Impact Index Per Article: 9.5</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1002/hep.32140','34490644', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(12);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(12);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(12);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(12);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1002/hep.32140' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(10337);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://mc.manuscriptcentral.com/hep' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 09/03/2020]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/08/2021]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/06/2021]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 02/03/2023]</span></span> </div> <input type="hidden" name="doiv" id="doiv12" value="10.1002/hep.32140" /> <div style="display: none" id="articleAbstract12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND AND AIMS</div><div class="abstract-content">Ductular reaction (DR) expands in chronic liver diseases and correlates with disease severity. Besides its potential role in liver regeneration, DR plays a role in the wound-healing response of the liver, promoting periductular fibrosis and inflammatory cell recruitment. However, there is no information regarding its role in intrahepatic angiogenesis. In the current study we investigated the potential contribution of DR cells to hepatic vascular remodeling during chronic liver disease. </div><div class="abstract-label">APPROACH AND RESULTS</div><div class="abstract-content">In mouse models of liver injury, DR cells express genes involved in angiogenesis. Among angiogenesis-related genes, the expression of Slit2 and its receptor Roundabout 1 (Robo1) was localized in DR cells and neoangiogenic vessels, respectively. The angiogenic role of the Slit2-Robo1 pathway in chronic liver disease was confirmed in ROBO1/2-/+ mice treated with 3,5-diethoxycarbonyl-1,4-dihydrocollidine, which displayed reduced intrahepatic neovascular density compared to wild-type mice. However, ROBO1/2 deficiency did not affect angiogenesis in partial hepatectomy. In patients with advanced alcohol-associated disease, angiogenesis was associated with DR, and up-regulation of SLIT2-ROBO1 correlated with DR and disease severity. In vitro, human liver-derived organoids produced SLIT2 and induced tube formation of endothelial cells. </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">Overall, our data indicate that DR expansion promotes angiogenesis through the Slit2-Robo1 pathway and recognize DR cells as key players in the liver wound-healing response. </div> <a href="javascript:ShowArticleAbstract(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22alcoholic+liver+disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">alcoholic liver disease</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22alcoholic+hepatitis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">alcoholic hepatitis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22slit2%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">slit2</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22robo1%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">robo1</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22ductular+reaction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">ductular reaction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22progenitor+cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">progenitor cells</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22organoids%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">organoids</a></li></ul> <a href="javascript:ShowArticleKeywords(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Blood+Vessels%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Blood Vessels/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chronic+Disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chronic Disease</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Progression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Progression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression</a></li><li><a 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style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow13"> <td style="min-width: 40px; text-align: center;"> 13 </td> <td> <div id="citation13" class="article-citation"> <b>Rubio-Tomás T</b>, Rueda-Robles A, Plaza-Díaz J, Álvarez-Mercado AI. Nutrition and cellular senescence in obesity-related disorders. <em class='incite-journal-name' onclick='ShowInCiteJournal(169356);'>J Nutr Biochem</em> 2022;<b>99</b>:108861. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/34517097' target='_blank'>34517097</a> DOI: <a href='https://dx.doi.org/10.1016/j.jnutbio.2021.108861' target='_blank'>10.1016/j.jnutbio.2021.108861</a>]<span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.referencecitationanalysis.com/citearticles?term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22c%22%2c%22o%22%3anull%2c%22v%22%3a%2210.1016%2fj.jnutbio.2021.108861%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d' target='_blank'>Citation(s) in <i>RCA</i>: 3</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInflu('10.1016%2fj.jnutbio.2021.108861')">Impact Index Per Article: 1.5</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.jnutbio.2021.108861','34517097', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(13);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(13);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(13);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.jnutbio.2021.108861' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(169356);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 11/17/2020]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 05/29/2021]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/10/2021]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 02/06/2023]</span></span> </div> <input type="hidden" name="doiv" id="doiv13" value="10.1016/j.jnutbio.2021.108861" /> <div style="display: none" id="articleAbstract13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Adequate nutrition is vital for immune homeostasis. However, the incidence of obesity is increasing worldwide due to the adoption of the Western diet and a sedentary lifestyle. Obesity is associated with chronic inflammation which alters the function of adipose tissue, liver, pancreas, and the nervous system. Inflammation is related to cellular senescence, distinguished by irreversible cell cycle arrest. Senescent cells secrete the senescence-associated secretory phenotype (SASP) which contains pro-inflammatory factors. Targeting processes in senescence might have a salutary approach to obesity. The present review highlights the impact of an unhealthy diet on tissues affected by obesity, and the mechanisms that promote the consequent inflammation and senescence. </div> <a href="javascript:ShowArticleAbstract(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22aging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">aging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22diet%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">diet</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22inflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">inflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22microbiota+obesity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">microbiota obesity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22senescence%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">senescence</a></li></ul> <a href="javascript:ShowArticleKeywords(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cellular+Senescence%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cellular Senescence</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diet%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diet</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Obesity%2fcomplications%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Obesity/complications</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Obesity%2fimmunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Obesity/immunology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Obesity%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Obesity/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Obesity%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Obesity/physiopathology</a></li></ul> <a href="javascript:ShowArticleMeSH(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(13);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow14"> <td style="min-width: 40px; text-align: center;"> 14 </td> <td> <div id="citation14" class="article-citation"> <b>Rueda-Robles A</b>, Audano M, Álvarez-Mercado AI, Rubio-Tomás T. Functions of SMYD proteins in biological processes: What do we know? An updated review. <em class='incite-journal-name' onclick='ShowInCiteJournal(2717);'>Arch Biochem Biophys</em> 2021;<b>712</b>:109040. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/34555372' target='_blank'>34555372</a> DOI: <a href='https://dx.doi.org/10.1016/j.abb.2021.109040' target='_blank'>10.1016/j.abb.2021.109040</a>]<span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.referencecitationanalysis.com/citearticles?term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22c%22%2c%22o%22%3anull%2c%22v%22%3a%2210.1016%2fj.abb.2021.109040%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d' target='_blank'>Citation(s) in <i>RCA</i>: 15</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInflu('10.1016%2fj.abb.2021.109040')">Impact Index Per Article: 5.0</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.abb.2021.109040','34555372', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(14);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(14);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(14);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.abb.2021.109040' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(2717);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/16/2021]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/13/2021]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/16/2021]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/19/2022]</span></span> </div> <input type="hidden" name="doiv" id="doiv14" value="10.1016/j.abb.2021.109040" /> <div style="display: none" id="articleAbstract14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Epigenetic modifiers, such as methyltransferases, play crucial roles in the regulation of many biological processes, including development, cancer and multiple physiopathological conditions.</div><div class="abstract-label">SUMMARY</div><div class="abstract-content">The Su(Var)3-9, Enhancer-of-zeste and Trithorax (SET) and Myeloid, Nervy, and DEAF-1 (MYND) domain-containing (SMYD) protein family consists of five members in humans and mice (i.e. SMYD1, SMYD2, SMYD3, SMYD4 and SMYD5), which are known or predicted to have methyltransferase activity on histone and non-histone substrates. The abundance of information concerning SMYD2 and SMYD3 is of note, whereas the other members of the SMYD family have not been so thoroughly studied CONCLUSION: Here we review the literature regarding SMYD proteins published in the last five years, including basic molecular biology mechanistic studies using in vitro systems and animal models, as well as human studies with a more translational or clinical approach.</div> <a href="javascript:ShowArticleAbstract(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cancer%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cancer</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Development%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Development</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Epigenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Epigenetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Methylation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Methylation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22SMYD%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SMYD</a></li></ul> <a href="javascript:ShowArticleKeywords(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cardiovascular+Diseases%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cardiovascular Diseases/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Differentiation%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Differentiation/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heart%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heart/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Histone-Lysine+N-Methyltransferase%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Histone-Lysine N-Methyltransferase/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Histone-Lysine+N-Methyltransferase%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Histone-Lysine N-Methyltransferase/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Histone-Lysine+N-Methyltransferase%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Histone-Lysine N-Methyltransferase/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Muscle%2c+Skeletal%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Muscle, Skeletal/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mutation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mutation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neoplasms%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neoplasms/physiopathology</a></li></ul> <a href="javascript:ShowArticleMeSH(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(14);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow15"> <td style="min-width: 40px; text-align: center;"> 15 </td> <td> <div id="citation15" class="article-citation"> <b>Rueda-Robles A</b>, Rubio-Tomás T, Plaza-Diaz J, Álvarez-Mercado AI. Impact of Dietary Patterns on <i>H. pylori</i> Infection and the Modulation of Microbiota to Counteract Its Effect. A Narrative Review. <em class='incite-journal-name' onclick='ShowInCiteJournal(18751);'>Pathogens</em> 2021;<b>10</b>:875. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/34358024' target='_blank'>34358024</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308520' target='_blank'>PMC8308520</a> DOI: <a href='https://dx.doi.org/10.3390/pathogens10070875' target='_blank'>10.3390/pathogens10070875</a>]<span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.referencecitationanalysis.com/citearticles?term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22c%22%2c%22o%22%3anull%2c%22v%22%3a%2210.3390%2fpathogens10070875%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d' target='_blank'>Citation(s) in <i>RCA</i>: 2</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInflu('10.3390%2fpathogens10070875')">Impact Index Per Article: 0.7</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.3390/pathogens10070875','34358024', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(15);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(15);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.3390/pathogens10070875' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://rcastoragev2.blob.core.windows.net/f0ce298cc8205197d4ef509d1ce1f914/PMC8308520.pdf' target='_blank'>Download PDF</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="openf" onclick="OpenFigures('10.3390/pathogens10070875');">Figures</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(18751);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/24/2021]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/07/2021]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 07/09/2021]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 12/12/2022]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv15" value="10.3390/pathogens10070875" /> <div style="display: none" id="articleAbstract15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Helicobacter pylori (H. pylori) is a Gram-negative bacterium that colonizes the stomach and can induce gastric disease and intra-gastric lesions, including chronic gastritis, peptic ulcers, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. This bacterium is responsible for long-term complications of gastric disease. The conjunction of host genetics, immune response, bacterial virulence expression, diet, micronutrient availability, and microbiome structure influence the disease outcomes related to chronic H. pylori infection. In this regard, the consumption of unhealthy and unbalanced diets can induce microbial dysbiosis, which infection with H. pylori may contribute to. However, to date, clinical trials have reported controversial results and current knowledge in this field is inconclusive. Here, we review preclinical studies concerning the changes produced in the microbiota that may be related to H. pylori infection, as well as the involvement of diet. We summarize and discuss the last approaches based on the modulation of the microbiota to improve the negative impact of H. pylori infection and their potential translation from bench to bedside. </div> <a href="javascript:ShowArticleAbstract(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Helicobacter+pylori%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Helicobacter pylori</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22diet%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">diet</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22experimental+models%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">experimental models</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22gastrointestinal+microbiota%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">gastrointestinal microbiota</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22therapeutic+approaches%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">therapeutic approaches</a></li></ul> <a href="javascript:ShowArticleKeywords(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(15);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow16"> <td style="min-width: 40px; text-align: center;"> 16 </td> <td> <div id="citation16" class="article-citation"> <b>Rubio-Tomás T</b>. The SMYD family proteins in immunology: An update of their obvious and non-obvious relations with the immune system. <em class='incite-journal-name' onclick='ShowInCiteJournal(171993);'>Heliyon</em> 2021;<b>7</b>:e07387. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/34235289' target='_blank'>34235289</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246384' target='_blank'>PMC8246384</a> DOI: <a href='https://dx.doi.org/10.1016/j.heliyon.2021.e07387' target='_blank'>10.1016/j.heliyon.2021.e07387</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.heliyon.2021.e07387','34235289', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(16);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(16);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.heliyon.2021.e07387' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://rcastoragev2.blob.core.windows.net/d435870f40f4a3e2c2212d2d506830e9/PMC8246384.pdf' target='_blank'>Download PDF</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="openf" onclick="OpenFigures('10.1016/j.heliyon.2021.e07387');">Figures</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(171993);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/18/2021]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 06/15/2021]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 06/21/2021]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 12/05/2022]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv16" value="10.1016/j.heliyon.2021.e07387" /> <div style="display: none" id="articleAbstract16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <p>Epigenetics is an emerging field, due to its relevance in the regulation of a wide range of biological processes. The Su(Var)3–9, Enhancer-of-zeste and Trithorax (SET) and Myeloid, Nervy, and DEAF-1 (MYND) domain-containing (SMYD) proteins, named SMYD1, SMYD2, SMYD3, SMYD4 and SMYD5, are enzymes that catalyse methylation of histone and non-histone substrates, thereby playing a key role in gene expression regulation in many biological contexts, such as muscle development and physiology, haematopoiesis and many types of cancer. This review focuses on a relatively unexplored aspect of SMYD family members - their relation with immunology. Here, immunology is defined in the broadest sense of the word, including basic research on macrophage function or host immunity against pathogen infection, as well as clinical studies, most of which are centred on blood cancers.</p> <a href="javascript:ShowArticleAbstract(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cancer%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cancer</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Epigenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Epigenetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Immunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Immunology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Methyltransferases%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Methyltransferases</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Muscle%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Muscle</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22SMYD%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SMYD</a></li></ul> <a href="javascript:ShowArticleKeywords(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(16);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow17"> <td style="min-width: 40px; text-align: center;"> 17 </td> <td> <div id="citation17" class="article-citation"> <b>Blaya D</b>, Rubio-Tomás T, Rodrigo-Torres D, Lozano J, Coll M, Argemi J, Altamirano J, Affò S, Morales-Ibanez O, Gratacós-Ginès J, Pose E, Tanguy M, Issoufaly T, Rautou PE, Bataller R, Caballería J, Sancho-Bru P. Endothelial dysfunction markers predict short-term mortality in patients with severe alcoholic hepatitis. <em class='incite-journal-name' onclick='ShowInCiteJournal(10339);'>Hepatol Int</em> 2021;<b>15</b>:1006-1017. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/33954832' target='_blank'>33954832</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113804' target='_blank'>PMC10113804</a> DOI: <a href='https://dx.doi.org/10.1007/s12072-021-10165-y' target='_blank'>10.1007/s12072-021-10165-y</a>]<span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.referencecitationanalysis.com/citearticles?term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22c%22%2c%22o%22%3anull%2c%22v%22%3a%2210.1007%2fs12072-021-10165-y%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d' target='_blank'>Citation(s) in <i>RCA</i>: 7</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInflu('10.1007%2fs12072-021-10165-y')">Impact Index Per Article: 2.3</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s12072-021-10165-y','33954832', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(17);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(17);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s12072-021-10165-y' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(10339);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/hepi/default1.aspx' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 12/04/2020]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 02/22/2021]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 02/07/2023]</span></span> </div> <input type="hidden" name="doiv" id="doiv17" value="10.1007/s12072-021-10165-y" /> <div style="display: none" id="articleAbstract17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">OBJECTIVES</div><div class="abstract-content">Alcoholic hepatitis (AH) is a severe condition characterized by a marked inflammatory response and high short-term mortality. Endothelial dysfunction (ED) is an early event in vascular and inflammatory disorders. The aim of this study is to evaluate ED in AH patients.</div><div class="abstract-label">METHODS</div><div class="abstract-content">Prognostic value of ED biomarkers was evaluated in patients with severe AH (n = 67), compensated alcoholic cirrhosis (n = 15), heavy drinkers without liver disease (n = 15) and controls (n = 9), and in a validation cohort of 50 patients with AH. Gene expression of ED markers was analyzed in liver tissue.</div><div class="abstract-label">RESULTS</div><div class="abstract-content">Plasma levels of ED markers such as vascular cell adhesion molecule 1 (VCAM-1), intercellular adhesion molecule 1 (ICAM-1), E-selectin and von Willebrand factor (vWF) increased along alcohol-related liver disease (ALD) progression. Intergroup analysis showed a significant increase of these markers in AH patients. In addition, VCAM-1 showed a positive correlation with Maddrey, MELD and ABIC scores and inflammation parameters (i.e. C-reactive protein and LPS levels). Importantly, levels of VCAM-1 were higher in patients with increased mortality and were independently associated with short-term survival (90-day) when adjusted by ABIC score. These results were confirmed in an independent cohort of AH patients. In addition, severe AH patients showed altered hepatic expression of ED markers.</div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">In this study we show that advanced ALD and particularly severe AH is associated with an increase of ED biomarkers, which correlate with patient outcomes. These results suggest that ED may be a pathogenic event in AH and highlight endothelial factors as potential biomarkers in AH.</div> <a href="javascript:ShowArticleAbstract(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alcoholic+liver+disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alcoholic liver disease</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alcoholic+liver+disease+(ALD)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alcoholic liver disease (ALD)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Biomarkers%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Biomarkers</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22E-selectin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">E-selectin</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hepatic+inflammation%3b+patient+outcomes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hepatic inflammation; patient outcomes</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22ICAM-1%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">ICAM-1</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Vascular+cell+adhesion+molecule+1+(VCAM-1)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Vascular cell adhesion molecule 1 (VCAM-1)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Vascular+dysfunction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Vascular dysfunction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Von-Willebrand+Factor%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Von-Willebrand Factor</a></li></ul> <a href="javascript:ShowArticleKeywords(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(17);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow18"> <td style="min-width: 40px; text-align: center;"> 18 </td> <td> <div id="citation18" class="article-citation"> <b>Aguilar-Bravo B</b>, Rodrigo-Torres D, Ariño S, Coll M, Pose E, Blaya D, Graupera I, Perea L, Vallverdú J, Rubio-Tomás T, Dubuquoy L, Armengol C, Nigro AL, Stärkel P, Mathurin P, Bataller R, Caballería J, Lozano JJ, Ginès P, Sancho-Bru P. Ductular Reaction Cells Display an Inflammatory Profile and Recruit Neutrophils in Alcoholic Hepatitis. <em class='incite-journal-name' onclick='ShowInCiteJournal(10337);'>Hepatology</em> 2019;<b>69</b>:2180-2195. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/30565271' target='_blank'>30565271</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189898' target='_blank'>PMC9189898</a> DOI: <a href='https://dx.doi.org/10.1002/hep.30472' target='_blank'>10.1002/hep.30472</a>]<span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.referencecitationanalysis.com/citearticles?term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22c%22%2c%22o%22%3anull%2c%22v%22%3a%2210.1002%2fhep.30472%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d' target='_blank'>Citation(s) in <i>RCA</i>: 50</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInflu('10.1002%2fhep.30472')">Impact Index Per Article: 10.0</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1002/hep.30472','30565271', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(18);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1002/hep.30472' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(10337);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://mc.manuscriptcentral.com/hep' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/02/2018]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 12/13/2018]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 12/19/2022]</span></span> </div> <input type="hidden" name="doiv" id="doiv18" value="10.1002/hep.30472" /> <div style="display: none" id="articleAbstract18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Chronic liver diseases are characterized by the expansion of ductular reaction (DR) cells and the expression of liver progenitor cell (LPC) markers. In alcoholic hepatitis (AH), the degree of DR expansion correlates with disease progression and short-term survival. However, little is known about the biological properties of DR cells, their impact on the pathogenesis of human liver disease, and their contribution to tissue repair. In this study, we have evaluated the transcriptomic profile of DR cells by laser capture microdissection in patients with AH and assessed its association with disease progression. The transcriptome analysis of cytokeratin 7-positive (KRT7<sup>+</sup> ) DR cells uncovered intrinsic gene pathways expressed in DR and genes associated with alcoholic liver disease progression. Importantly, DR presented a proinflammatory profile with expression of neutrophil recruiting C-X-C motif chemokine ligand (CXC) and C-C motif chemokine ligand chemokines. Moreover, LPC markers correlated with liver expression and circulating levels of inflammatory mediators such as CXCL5. Histologically, DR was associated with neutrophil infiltration at the periportal area. In order to model the DR and to assess its functional role, we generated LPC organoids derived from patients with cirrhosis. Liver organoids mimicked the transcriptomic and proinflammatory profile of DR cells. Conditioned medium from organoids induced neutrophil migration and enhanced cytokine expression in neutrophils. Likewise, neutrophils promoted the proinflammatory profile and the expression of chemokines of liver organoids. Conclusion: Transcriptomic and functional analysis of KRT7<sup>+</sup> cells indicate that DR has a proinflammatory profile and promote neutrophil recruitment. These results indicate that DR may be involved in the liver inflammatory response in AH, and suggest that therapeutic strategies targeting DR cells may be useful to mitigate the inflammatory cell recruitment in AH.</div> <a href="javascript:ShowArticleAbstract(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <a href="javascript:ShowArticleKeywords(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(18);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow19"> <td style="min-width: 40px; text-align: center;"> 19 </td> <td> <div id="citation19" class="article-citation"> <b>Rubio-Tomás T</b>, Aguilar-Bravo B, Sancho-Bru P. Genetic Lineage Tracing of Biliary Epithelial Cells. <em class='incite-journal-name' onclick='ShowInCiteJournal(169595);'>Methods Mol Biol</em> 2019;<b>1905</b>:45-57. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/30536089' target='_blank'>30536089</a> DOI: <a href='https://dx.doi.org/10.1007/978-1-4939-8961-4_5' target='_blank'>10.1007/978-1-4939-8961-4_5</a>]<span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.referencecitationanalysis.com/citearticles?term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22c%22%2c%22o%22%3anull%2c%22v%22%3a%2210.1007%2f978-1-4939-8961-4_5%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d' target='_blank'>Citation(s) in <i>RCA</i>: 4</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInflu('10.1007%2f978-1-4939-8961-4_5')">Impact Index Per Article: 0.8</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/978-1-4939-8961-4_5','30536089', 'Teresa Rubio-Tomás')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(19);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(19);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/978-1-4939-8961-4_5' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(169595);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 01/10/2023]</span></span> </div> <input type="hidden" name="doiv" id="doiv19" value="10.1007/978-1-4939-8961-4_5" /> <div style="display: none" id="articleAbstract19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Lineage tracing of liver cells is a powerful tool to understand liver embryonic development, healthy liver cell homeostasis, tissue repair, and regeneration. Lineage tracing of biliary epithelial cells (BECs) in the adult liver has been used to assess the contribution of the biliary epithelium to liver injury, regeneration, and disease. These studies have shown the contribution of BECs to the expansion of ductular reaction (DR) and liver progenitor cells (LPCs) and eventually the generation of new hepatocytes. Few genetic lineage-tracing mouse models have been proved to trace BECs. This chapter is focused on lineage tracing of BECs in mouse models of liver injury and regeneration. First, we mention different existing approaches to trace the biliary epithelium based on proteins specifically expressed by BECs such as sex-determining region Y-box 9 (SOX9), osteopontin (OPN), and cytokeratin-19 (KRT19). Second, we describe mouse models that can be used to evaluate cell fate during liver injury and regeneration (i.e., partial hepatectomy (PHx), acute liver injury models, and chronic liver damage models such as 3,5-diethoxycarbonyl-1,4-dihydro-collidin (DDC) diet, choline-deficient ethionine-supplemented (CDE) diet, or chronic carbon tetrachloride (CCl<sub>4</sub>) administration). Third, we suggest possible readouts to assess BECs fate based on immunofluorescence analysis.</div> <a href="javascript:ShowArticleAbstract(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animal+models%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animal models</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Biliary+epithelial+cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Biliary epithelial cells</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chronic+liver+injury%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chronic liver injury</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ductular+reaction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ductular reaction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Lineage+tracing%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Lineage tracing</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Liver+progenitor+cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Liver progenitor cells</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Liver+regeneration%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Liver regeneration</a></li></ul> <a href="javascript:ShowArticleKeywords(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(19);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> </tbody></table> <div class="search-pager-container"> <div class="dxpLite_MetropolisBlue" id="RootHolder_SearchResultPager" style="margin-top: 20px; margin-bottom: 20px;"> <b class="dxp-lead dxp-button dxp-bi dxp-disabledButton"><img class="dxWeb_pPrevDisabled_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Prev" /></b><b class="dxp-summary" style="margin-left:0px;">Page 1 of 1 </b><b class="dxp-num dxp-current 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src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleCitationPopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleCitationPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1115091042" type="text/javascript">  </script> <div id="RootHolder_chartPopupControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:1000px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_chartPopupControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam"></span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content" style="overflow-x:hidden;overflow-y:scroll;">    </div> </div> </div> </div><div id="RootHolder_chartPopupControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_chartPopupControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_chartPopupControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_chartPopupControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_420552910" type="text/javascript">  </script> <div id="RootHolder_pcImportArticlesControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:50px;width:50px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_pcImportArticlesControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Import Articles</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="RootHolder_pcImportArticlesControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_pcImportArticlesControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_pcImportArticlesControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_pcImportArticlesControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_365297802" type="text/javascript">  </script> <div id="RootHolder_pcEditArticleControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_pcEditArticleControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Edit My Journal Article</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content" style="overflow-x:hidden;overflow-y:scroll;">    </div> </div> </div> </div><div id="RootHolder_pcEditArticleControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_pcEditArticleControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_pcEditArticleControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_pcEditArticleControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_298765222" type="text/javascript">  </script> <div id="RootHolder_userIndexComputePopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:200px;width:400px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header dxpc-withBtn" style="font-size:20px;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Article Influence Index</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for <span id="RootHolder_userIndexComputePopup_InfluenceIndexTitle2">Article Influence Index</span></b> </p> <p> Total Citations in Crossref ÷ Total Articles = <span id="RootHolder_userIndexComputePopup_InfluenceIndexTitle3">Article Influence Index</span><sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="RootHolder_userIndexComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_userIndexComputePopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_userIndexComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1286575841" type="text/javascript">  </script> <div id="RootHolder_articleExportPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:280px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow" style="font-size:11pt;"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_articleExportPopup_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Export Articles to File</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="dxtcLite_MetropolisBlue dxtcSys dxtc-init dxtc-top dxtc-pc" id="RootHolder_articleExportPopup_ExportFilePageControl" style="width:100%;"> <ul class="dxtc-strip dxtc-row dxtc-stripContainer"> <li class="dxtc-leftIndent"> </li><li class="dxtc-tab dxtc-lead" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-activeTab dxtc-lead"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-spacer"> </li><li class="dxtc-tab dxtc-last"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-activeTab dxtc-last" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-rightIndent"> </li> </ul><div class="dxtc-content"> <div> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_SearchTermText1">Teresa Rubio-Tomás (19 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:5px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_1662381219" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailEndIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" value="19" type="text" /></td> </tr> </table><script id="dxss_616434442" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_1167331127" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_54524200" type="text/javascript">  </script><script id="dxss_1678130197" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" style="font-weight:bold;">JCR Year:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" type="hidden" value="2023" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" value="2023" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2023</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2022</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2021</td> </tr> </table> </div></td> </tr> </table><script id="dxss_830317689" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_167955898" type="text/javascript">  </script><script id="dxss_2013408041" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1062639383" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_104403608" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1973673553" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_6" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLTSys dxflItemSys dxflCheckBoxWithTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" style="font-weight:bold;">Record Content:</label></td> </tr><tr> <td class="dxflNestedControlCell_MetropolisBlue"> <table> <tr> <td style="vertical-align: middle; padding: 5px;"> <table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields" style="color:#BD4100;"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$cbSelectAllFields" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label>Select All Fields</label></td> </tr> </table><script id="dxss_1176833720" type="text/javascript">  </script> </td> </tr> <tr> <td style="padding: 5px;"> <table class="dxeCheckBoxList_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields" style="width:100%;border-collapse:separate;"> <tr> <td class="dxe"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields" /><table style="width:100%;"> <tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB0" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Author(s)</label></td> </tr> </table><script id="dxss_771536870" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB1" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Title</label></td> </tr> </table><script id="dxss_1086331335" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB2" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Keywords</label></td> </tr> </table><script id="dxss_1308541020" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB3" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">MESH Headings</label></td> </tr> </table><script id="dxss_896786043" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB4" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Journal Title</label></td> </tr> </table><script id="dxss_450242410" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB5" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Year</label></td> </tr> </table><script id="dxss_765036875" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB6" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Type</label></td> </tr> </table><script id="dxss_1629835480" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB7" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Language</label></td> </tr> </table><script id="dxss_1218080503" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB8" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Published Date</label></td> </tr> </table><script id="dxss_1428514578" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB9" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author</label></td> </tr> </table><script id="dxss_1113720113" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB10" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author’s Affiliations</label></td> </tr> </table><script id="dxss_310841941" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB11" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author</label></td> </tr> </table><script id="dxss_1301541094" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB12" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author’s Affiliations</label></td> </tr> </table><script id="dxss_675718561" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB13" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Email</label></td> </tr> </table><script id="dxss_2006865700" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB14" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">All Authors's Affiliations</label></td> </tr> </table><script id="dxss_1204905793" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB15" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Grant</label></td> </tr> </table><script id="dxss_407477242" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB16" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">ISSN</label></td> </tr> </table><script id="dxss_218345291" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB17" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Publisher</label></td> </tr> </table><script id="dxss_1394037744" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB18" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexing / Abstracting</label></td> </tr> </table><script id="dxss_319681069" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB19" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Factor</label></td> </tr> </table><script id="dxss_1292701966" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB20" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">JCR Quartile</label></td> </tr> </table><script id="dxss_1844280938" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB21" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Index Per Article</label></td> </tr> </table><script id="dxss_838303323" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB22" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Category</label></td> </tr> </table><script id="dxss_1464125856" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB23" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Times Cited in RCA</label></td> </tr> </table><script id="dxss_148257179" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB24" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Peer-Reviewed Journal</label></td> </tr> </table><script id="dxss_950217086" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB25" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Open Access</label></td> </tr> </table><script id="dxss_1732367175" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB26" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">DOI</label></td> </tr> </table><script id="dxss_1936777588" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB27" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">PMID</label></td> </tr> </table><script id="dxss_745806673" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB28" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Citation</label></td> </tr> </table><script id="dxss_1835441810" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB29" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexed in RCA</label></td> </tr> </table><script id="dxss_847142451" type="text/javascript">  </script></td><td></td><td></td> </tr> </table></td> </tr> </table><script id="dxss_1169734383" type="text/javascript">  </script> </td> </tr> </table> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_7" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportedDetailFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_1198171345" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_1960175520" type="text/javascript">  </script> </div> </div><div style="display:none;"> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_SearchTermText2">Teresa Rubio-Tomás (19 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:10px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_814491935" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportEndSIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" value="19" type="text" /></td> </tr> </table><script id="dxss_1331245653" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:10px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_2046065225" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_1926633208" type="text/javascript">  </script><script id="dxss_228619664" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:20px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" type="hidden" value="1" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" value="Excel" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1509722775" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_960798088" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_835950349" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportedFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_308093146" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_424125632" type="text/javascript">  </script> </div> </div> </div> </div><b class="dx-clear"></b><table id="RootHolder_articleExportPopup_ExportFilePageControl_LP" class="dxtcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_TL">Loading…</span></td> </tr> </table><script id="dxss_2124675053" type="text/javascript">  </script> </div> </div><div class="dxpc-footer"> <div class="popup-footer-button-container"> <div class="dxbButton_MetropolisBlue DefaultButton dxbButtonSys dxbTSys" id="RootHolder_articleExportPopup_TPCFm1_btnExportArticles" 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All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA </div> <div class="scroll"> <a href="#top" target="_self"> <img src="/Contents/Images/backtop3.png" /> </a> </div> <div id="categorySelectorPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Select the Category</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="categorySelectorPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="categorySelectorPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="categorySelectorPopup_TL">Loading…</span></td> </tr> </table><div id="categorySelectorPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_166253781" type="text/javascript">  </script> <div id="pcLoginPopUp_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:700px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="pcLoginPopUp_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="pcLoginPopUp_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="pcLoginPopUp_TL">Loading…</span></td> </tr> </table><div id="pcLoginPopUp_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_430910140" type="text/javascript">  </script> <div id="aiComputePopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:200px;width:300px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header dxpc-withBtn" style="font-size:20px;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Impact Index Per Article</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for Impact Index Per Article</b> </p> <p> Times Cited ÷ Number of Years = Impact Index Per Article<sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="aiComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="aiComputePopup_TL">Loading…</span></td> </tr> </table><div id="aiComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_698179129" type="text/javascript">  </script> <script type="text/javascript"> //<![CDATA[ var callBackFrameUrl='/WebResource.axd?d=beToSAE3vdsL1QUQUxjWdX-3aFLejnBliGvqSCZYULGFdxZmRlcJcqs71AKVNTQEXljNmd0slFkUZ_AFaCke4Q2&t=638628207619783110'; WebForm_InitCallback();//]]> </script> </form> </body> </html>

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