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Kanabinoidni receptor tip 1 — Википедија

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значајних жена\u003C/a\u003E\u003C/b\u003E на Викицитату.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\n\u003Cdiv class=\"noticebanner\"\u003E\u003Cdiv class=\"plainlinks\" style=\"background-color: #FBEBEA; border-radius:5px; margin-top:10px; position:relative; border: 1px solid #aaa; font-family: \u0026#39;Helvetica\u0026#39;, \u0026#39;Arial\u0026#39;, sans-serif; line-height: 18px; box-shadow: 0 1px 1px rgba( 0, 0, 0, 0.15 ); overflow:hidden;\"\u003E\u003Cdiv style=\"display:block; top:4px; width:100%; text-align:center;;\"\u003E\u003Cdiv style=\"color:#000085; font-size:25px; line-height:25px\"\u003E\u003Cdiv style=\"padding-left:50px;\"\u003E\u003C/div\u003E\u003C/div\u003E\u003Cdiv style=\"padding-top:2px; color:#444; font-size:1.15em; line-height:1.5;\"\u003E\u003Cdiv style=\"padding-left:8px; padding-right:8px;\"\u003EПридружите се \u003Cb\u003E\u003Ca href=\"/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0:%D0%90%D0%BA%D1%86%D0%B8%D1%98%D0%B0_%D0%BF%D1%80%D0%BE%D1%88%D0%B8%D1%80%D0%B8%D0%B2%D0%B0%D1%9A%D0%B0_%D0%BA%D0%BB%D0%B8%D1%86%D0%B0\" title=\"Википедија:Акција проширивања клица\"\u003Eакцији проширивања клица\u003C/a\u003E\u003C/b\u003E.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E";}}());</script></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="Сајт"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="Садржај" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" 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href="#Struktura"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Struktura</span> </div> </a> <ul id="toc-Struktura-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Mehanizam" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Mehanizam"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Mehanizam</span> </div> </a> <ul id="toc-Mehanizam-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Izražavanje" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Izražavanje"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Izražavanje</span> </div> </a> <ul id="toc-Izražavanje-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Reference" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Reference"> <div 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<nav aria-label="Садржај" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Прикажи/сакриј садржај" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Прикажи/сакриј садржај</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Kanabinoidni receptor tip 1</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Чланак на другим језицима. 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class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/CNR1" title="CNR1 — босански" lang="bs" hreflang="bs" data-title="CNR1" data-language-autonym="Bosanski" data-language-local-name="босански" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Receptor_cannabinoide_1" title="Receptor cannabinoide 1 — каталонски" lang="ca" hreflang="ca" data-title="Receptor cannabinoide 1" data-language-autonym="Català" data-language-local-name="каталонски" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/CNR1" title="CNR1 — велшки" lang="cy" hreflang="cy" data-title="CNR1" data-language-autonym="Cymraeg" data-language-local-name="велшки" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Kanabinoidn%C3%AD_receptor_1" title="Kanabinoidní receptor 1 — чешки" lang="cs" hreflang="cs" data-title="Kanabinoidní receptor 1" data-language-autonym="Čeština" data-language-local-name="чешки" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Cannabinoid-Rezeptor_1" title="Cannabinoid-Rezeptor 1 — немачки" lang="de" hreflang="de" data-title="Cannabinoid-Rezeptor 1" data-language-autonym="Deutsch" data-language-local-name="немачки" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Cannabinoid_receptor_1" title="Cannabinoid receptor 1 — енглески" lang="en" hreflang="en" data-title="Cannabinoid receptor 1" data-language-autonym="English" data-language-local-name="енглески" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Receptor_cannabinoide_de_tipo_1" title="Receptor cannabinoide de tipo 1 — шпански" lang="es" hreflang="es" data-title="Receptor cannabinoide de tipo 1" data-language-autonym="Español" data-language-local-name="шпански" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/1_motako_kanabinoide_errezeptore" title="1 motako kanabinoide errezeptore — баскијски" lang="eu" hreflang="eu" data-title="1 motako kanabinoide errezeptore" data-language-autonym="Euskara" data-language-local-name="баскијски" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/R%C3%A9cepteur_cannabino%C3%AFde_de_type_1" title="Récepteur cannabinoïde de type 1 — француски" lang="fr" hreflang="fr" data-title="Récepteur cannabinoïde de type 1" data-language-autonym="Français" data-language-local-name="француски" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Receptory_kannabinoidowe_typu_1" title="Receptory kannabinoidowe typu 1 — пољски" lang="pl" hreflang="pl" data-title="Receptory kannabinoidowe typu 1" data-language-autonym="Polski" data-language-local-name="пољски" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Receptor_canabinoide_tipo_1" title="Receptor canabinoide tipo 1 — португалски" lang="pt" hreflang="pt" data-title="Receptor canabinoide tipo 1" data-language-autonym="Português" data-language-local-name="португалски" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Kanabinoidni_receptor_tip_1" title="Kanabinoidni receptor tip 1 — српскохрватски" lang="sh" hreflang="sh" data-title="Kanabinoidni receptor tip 1" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="српскохрватски" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/CB1-receptor" title="CB1-receptor — шведски" lang="sv" hreflang="sv" data-title="CB1-receptor" data-language-autonym="Svenska" data-language-local-name="шведски" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/CNR1" title="CNR1 — украјински" lang="uk" 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th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox"><tbody><tr><th colspan="4" class="infobox-above">Kanabinoidni receptor 1</th></tr><tr><td colspan="4" class="infobox-image"> <span class="mw-image-border" typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:PDB_1lvq_EBI.jpg" class="mw-file-description"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/5e/PDB_1lvq_EBI.jpg/250px-PDB_1lvq_EBI.jpg" decoding="async" width="250" height="137" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/5e/PDB_1lvq_EBI.jpg/375px-PDB_1lvq_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/5/5e/PDB_1lvq_EBI.jpg 2x" data-file-width="455" data-file-height="250" /></a></span><div class="infobox-caption">Prikaz CNR1 iz <a href="/wiki/Proteinska_banka_podataka" title="Proteinska banka podataka"> PDB</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1LVQ">1LVQ</a></span>&#8203;</div></td></tr><tr><th colspan="4" class="infobox-header" style="background-color: #ddd">Dostupne strukture</th></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1LVQ">1LVQ</a></span>&#8203;, <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1LVR">1LVR</a></span>&#8203;, <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2B0Y">2B0Y</a></span>&#8203;, <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2KOE">2KOE</a></span>&#8203;</td></tr><tr><th colspan="4" class="infobox-header" style="background-color: #ddd">Identifikatori</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/Organizacija_za_ljudski_genom" title="Organizacija za ljudski genom">Simboli</a></th><td colspan="3" class="infobox-data" style="background-color: #eee"> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=2159">CNR1</a>; CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR</span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">Vanjski ID</th><td colspan="3" class="infobox-data" style="background-color: #eee"> <span class="plainlinks"><a href="/wiki/%D0%9C%D0%B5%D0%BD%D0%B4%D0%B5%D0%BB%D0%BE%D0%B2%D1%81%D0%BA%D0%BE_%D0%BD%D0%B0%D1%81%D0%BB%D0%B5%D1%92%D0%B8%D0%B2%D0%B0%D1%9A%D0%B5_%D0%BA%D0%BE%D0%B4_%D1%87%D0%BE%D0%B2%D0%B5%D0%BA%D0%B0" title="Менделовско наслеђивање код човека">OMIM</a>:&#160;<a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=114610">114610 </a></span> <span class="plainlinks"><a href="/wiki/%D0%98%D0%BD%D1%84%D0%BE%D1%80%D0%BC%D0%B0%D1%82%D0%B8%D0%BA%D0%B0_%D0%BC%D0%B8%D1%88%D1%98%D0%B5%D0%B3_%D0%B3%D0%B5%D0%BD%D0%BE%D0%BC%D0%B0" title="Информатика мишјег генома">MGI</a>:&#160;<a rel="nofollow" class="external text" href="http://www.informatics.jax.org/searches/accession_report.cgi?id=MGI:104615">104615 </a></span> <span class="plainlinks"><a href="/wiki/HomoloGene" title="HomoloGene">HomoloGene</a>:&#160;<a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=homologene&amp;dopt=HomoloGene&amp;list_uids=7273">7273 </a></span> <a href="/wiki/International_Union_of_Basic_and_Clinical_Pharmacology" class="mw-redirect" title="International Union of Basic and Clinical Pharmacology">IUPHAR</a>: <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.iuphar-db.org/DATABASE/ObjectDisplayForward?objectId=56">CB<sub>1</sub></a></span> <a href="/wiki/GeneCards" title="GeneCards">GeneCards</a>: <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&amp;id=1268">CNR1 Gene</a></span></td></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <table class="collapsible collapsed" style="border: none; padding: 0; margin: 0; width: 100%; text-align: left"> <tbody><tr style="background-color: #ddd; text-align: center"> <th colspan="2"><a href="/wiki/Ontologija_gena" title="Ontologija gena">Ontologija gena</a></th> </tr> <tr> <th style="background-color: #c3fdb8">Molekularna funkcija</th> <td style="background-color: #eee"><big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&amp;search_constraint=terms&amp;depth=0&amp;query=GO:0004871">aktivnost prenosnika signalA</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&amp;search_constraint=terms&amp;depth=0&amp;query=GO:0004872">receptorska aktivnost</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&amp;search_constraint=terms&amp;depth=0&amp;query=GO:0004949">aktivnost kanabinoidnog receptora</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&amp;search_constraint=terms&amp;depth=0&amp;query=GO:0008144">vezivanje leka</a></span><br /></td> </tr> <tr> <th style="background-color: #c3fdb8">Celularna komponenta</th> <td style="background-color: #eee"><big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&amp;search_constraint=terms&amp;depth=0&amp;query=GO:0005792">mikrozom</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&amp;search_constraint=terms&amp;depth=0&amp;query=GO:0005886">ćelijska membrana</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&amp;search_constraint=terms&amp;depth=0&amp;query=GO:0005887">integralno sa ćelijskom membranom</a></span><br /></td> </tr> <tr> <th style="background-color: #c3fdb8">Biološki proces</th> <td style="background-color: #eee"><big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&amp;search_constraint=terms&amp;depth=0&amp;query=GO:0002866">pozitivna regulacija akutnog inflamatornog responsa na antigenski stimulus</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&amp;search_constraint=terms&amp;depth=0&amp;query=GO:0006950">respons na stres</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&amp;search_constraint=terms&amp;depth=0&amp;query=GO:0007187">G proteinska signalizacija, spregnuta sa cikličnim nukleotidnim sekundarnim glasnikom</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&amp;search_constraint=terms&amp;depth=0&amp;query=GO:0007188">G proteinska signalizacija, spregnuta sa cAMP nukleotidnim sekundarnim glasnikom</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&amp;search_constraint=terms&amp;depth=0&amp;query=GO:0007283">spermatogeneza</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&amp;search_constraint=terms&amp;depth=0&amp;query=GO:0007568">starenje</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&amp;search_constraint=terms&amp;depth=0&amp;query=GO:0007584">respons na nutrijent</a></span><br /></td> </tr> </tbody></table></td></tr><tr><th colspan="4" class="infobox-header" style="background-color: #ddd">Pregled RNK izražavanja</th></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <span typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:PBB_GE_CNR1_213436_at_tn.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/5/54/PBB_GE_CNR1_213436_at_tn.png/250px-PBB_GE_CNR1_213436_at_tn.png" decoding="async" width="250" height="132" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/5/54/PBB_GE_CNR1_213436_at_tn.png 1.5x" data-file-width="255" data-file-height="135" /></a></span></td></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://biogps.gnf.org/gene/1268/Dodatni">podaci</a></span></td></tr><tr><th colspan="4" class="infobox-header" style="background-color: #ddd">Ortolozi</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">Vrsta</th><td class="infobox-data infobox-data-a"> <b>Čovek</b></td><td class="infobox-data infobox-data-b"> <b>Miš</b></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/Entrez" title="Entrez">Entrez</a></th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&amp;cmd=retrieve&amp;dopt=default&amp;list_uids=1268&amp;rn=1">1268</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&amp;cmd=retrieve&amp;dopt=default&amp;list_uids=12801&amp;rn=1">12801</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/Ensembl" title="Ensembl">Ensembl</a></th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000118432;db=core">ENSG00000118432</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Mus_musculus/geneview?gene=ENSMUSG00000044288;db=core">ENSMUSG00000044288</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/UniProt" title="UniProt">UniProt</a></th><td class="infobox-data infobox-data-a"> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.uniprot.org/uniprot/P21554">P21554</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.uniprot.org/uniprot/P47746">P47746</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">RefSeq (mRNA)</th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001160226.1">NM_001160226.1</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_007726.3">NM_007726.3</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">RefSeq (protein)</th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001153698.1">NP_001153698.1</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_031752.1">NP_031752.1</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">Lokacija (UCSC)</th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=Human&amp;db=hg19&amp;position=chr6:88849583-88876078">Chr 6:<br />88.85 - 88.88 Mb</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=Mouse&amp;db=mm9&amp;position=chr4:34011568-34035806">Chr 4:<br />34.01 - 34.04 Mb</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/PubMed" title="PubMed">PubMed</a> pretraga</th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external autonumber" href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&amp;cmd=Link&amp;LinkName=gene_pubmed&amp;from_uid=1268">[1]</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external autonumber" href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&amp;cmd=Link&amp;LinkName=gene_pubmed&amp;from_uid=12801">[2]</a></span></td></tr></tbody></table> <p><b>Kanabinoidni receptor tip 1</b> (<i>CB<sub>1</sub></i>) je <a href="/wiki/G_protein_spregnuti_receptor" class="mw-redirect" title="G protein spregnuti receptor">G protein spregnuti</a> <a href="/wiki/Kanabinoidni_receptor" title="Kanabinoidni receptor">kanabinoidni receptor</a>. CB<sub>1</sub> je prvenstveno lociran u <a href="/wiki/%D0%9C%D0%BE%D0%B7%D0%B0%D0%BA" title="Мозак">mozgu</a>. On se aktivira <a href="/wiki/Kanabinoid" title="Kanabinoid">endokanabinoidnim</a> <a href="/wiki/%D0%9D%D0%B5%D1%83%D1%80%D0%BE%D1%82%D1%80%D0%B0%D0%BD%D1%81%D0%BC%D0%B8%D1%82%D0%B5%D1%80" title="Неуротрансмитер">neurotransmiterima</a> <a href="/wiki/Anandamid" title="Anandamid">anandamidom</a> i 2-arahidonoil gliceridom (<a href="/wiki/2-Arahidonoilglicerol" title="2-Arahidonoilglicerol">2-AG</a>); biljnim <a href="/wiki/Kanabinoid" title="Kanabinoid">kanabinoidima</a>, kao što je <a href="/wiki/Tetrahidrokanabinol" title="Tetrahidrokanabinol">THC</a>, aktivni sastojak <a href="/wiki/Psihoaktivni_lek" title="Psihoaktivni lek">psihoaktivnog leka</a> <a href="/wiki/Kanabis_(lek)" class="mw-redirect" title="Kanabis (lek)">kanabisa</a>; i sintetičkim analozima THC, poput <a href="/wiki/Tetrahidrokanabinol" title="Tetrahidrokanabinol">dronabinola</a>. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Struktura">Struktura</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Kanabinoidni_receptor_tip_1&amp;veaction=edit&amp;section=1" title="Уредите одељак „Struktura”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Kanabinoidni_receptor_tip_1&amp;action=edit&amp;section=1" title="Уреди извор одељка: Struktura"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>CB<sub>1</sub> receptor ima zajedničke strukturne karakteristike svih G protein spregnutih receptora. On poseduje <a href="/wiki/Sedam-transmembranski_domen_receptori" class="mw-redirect" title="Sedam-transmembranski domen receptori">sedam transmembranskih domena</a> povezanih sa tri ekstracelularne i tri intracelularne petlje, ekstracelularni <a href="/wiki/N-terminus" title="N-terminus">N-terminus</a>, i intracelularni <a href="/wiki/C-terminus" title="C-terminus">C-terminus</a>.<sup id="cite_ref-pmid11316486_1-0" class="reference"><a href="#cite_note-pmid11316486-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> Ovi receptori mogu da postoje kao <a href="/wiki/Proteinski_dimer" title="Proteinski dimer">homodimeri</a>, <a href="/wiki/Proteinski_dimer" title="Proteinski dimer">heterodimeri</a> ili <a href="/wiki/Oligomer" title="Oligomer">oligomeri</a> kad su koizraženi sa jednom ili više klasa G protein spregnutih receptora. Uočeni heterodimeri su A<sub>2A</sub>CB<sub>1</sub>, A<sub>2A</sub>, CB<sub>1</sub>D<sub>2</sub>, oreksin 1/CB1, CB1/D2,. Mnogi drugi su možda stabilni jedino in vivo.<sup id="cite_ref-pmid16570099_2-0" class="reference"><a href="#cite_note-pmid16570099-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> Postoje dokaza da ovi receptori poseduju <a href="/wiki/Alosterna_regulacija" title="Alosterna regulacija">alosterno</a> mesto vezivanja, koje može da postane biološki cilj za poboljšanje kliničkih modulatornih efekata kanabinoida.<sup id="cite_ref-pmid16570099_2-1" class="reference"><a href="#cite_note-pmid16570099-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Mehanizam">Mehanizam</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Kanabinoidni_receptor_tip_1&amp;veaction=edit&amp;section=2" title="Уредите одељак „Mehanizam”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Kanabinoidni_receptor_tip_1&amp;action=edit&amp;section=2" title="Уреди извор одељка: Mehanizam"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>CB<sub>1</sub> receptor je presinaptički <a href="/wiki/Heteroreceptor" title="Heteroreceptor">heteroreceptor</a> koji moduliše otpuštanje neurotransmitera kad je aktiviran. On funkcioniše na način koji je zavistan od doze, stereoselektivan i senzitivan na <a href="/wiki/Pertuzijski_toksin" title="Pertuzijski toksin">pertuzijski toksin</a>.<sup id="cite_ref-entrez_3-0" class="reference"><a href="#cite_note-entrez-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> CB<sub>1</sub> receptor aktiviraju <a href="/wiki/Kanabinoid" title="Kanabinoid">kanabinoidi</a>, prirodno formirani u telu (<a href="/wiki/Endokanabinoidi" class="mw-redirect" title="Endokanabinoidi">Endokanabinoidi</a>) ili uneseni kao <a href="/wiki/Kanabis_(lek)" class="mw-redirect" title="Kanabis (lek)">kanabis</a> ili srodno <a href="/wiki/Hemijska_sinteza" title="Hemijska sinteza">sintetičko</a> jedinjenje. </p><p>Iz istraživanja proizilazi da je većina CB<sub>1</sub> receptora spregnuta sa G<sub>i/o</sub> proteinima. Pri aktivaciji, CB<sub>1</sub> receptor deluje prvenstveno putem aktivacije <a href="/wiki/Gi_alfa_podjedinica" title="Gi alfa podjedinica">G<sub>i</sub></a>, čime se snižava intracelularna cAMP koncentracija putem inhibicije <a href="/wiki/%D0%95%D0%BD%D0%B7%D0%B8%D0%BC" title="Ензим">enzima</a> za njegovu produkciju, <a href="/wiki/Adenilat_ciklaza" class="mw-redirect" title="Adenilat ciklaza">adenilat ciklaze</a>, i povišava koncentracija <a href="/wiki/Mitogenom-aktivirane_proteinske_kinaze" title="Mitogenom-aktivirane proteinske kinaze">mitogenom-aktivirane proteinske kinaze</a> (MAP kinaze). Alternativno, u nekim retkim slučajevima aktivacija CB<sub>1</sub> receptora može da bude spregnuta sa <a href="/wiki/Gs_alfa_podjedinica" title="Gs alfa podjedinica">G<sub>s</sub></a> proteinima, koji stimulišu <a href="/wiki/Adenilat_ciklaza" class="mw-redirect" title="Adenilat ciklaza">adenilat ciklazu</a>.<sup id="cite_ref-pmid16570099_2-2" class="reference"><a href="#cite_note-pmid16570099-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> Poznato je da cAMP služi kao sekundarni glasnik koji se spreže sa mnoštvom jonskih kanala, uključujući <a href="/w/index.php?title=Unutra%C5%A1nje_ispravljaju%C4%87i_kalijumski_kanali&amp;action=edit&amp;redlink=1" class="new" title="Unutrašnje ispravljajući kalijumski kanali (страница не постоји)">unutrašnje ispravljajuće kalijumske kanale</a> (Kir ili IRK),<sup id="cite_ref-pmid16109430_4-0" class="reference"><a href="#cite_note-pmid16109430-4"><span class="cite-bracket">&#91;</span>4<span class="cite-bracket">&#93;</span></a></sup> i <a href="/w/index.php?title=Kalcijumov_kanal&amp;action=edit&amp;redlink=1" class="new" title="Kalcijumov kanal (страница не постоји)">kalcijumove kanale</a>, koji se aktiviraju cAMP zavisnom interakcijom sa molekulima poput <a href="/wiki/Proteinska_kinaza_A" title="Proteinska kinaza A">proteinske kinaze A</a> (PKA), <a href="/wiki/Proteinska_kinaza_C" title="Proteinska kinaza C">proteinske kinaze C</a> (PKC), <a href="/wiki/C-Raf" title="C-Raf">Raf-1</a>, <a href="/wiki/Ekstracelularnim_signalom_regulisana_kinaza" title="Ekstracelularnim signalom regulisana kinaza">ERK</a>, <a href="/w/index.php?title=C-Jun_N-terminalne_kinaze&amp;action=edit&amp;redlink=1" class="new" title="C-Jun N-terminalne kinaze (страница не постоји)">JNK</a>, <a href="/w/index.php?title=P38_mitogenom_aktivirana_proteinske_kinaze&amp;action=edit&amp;redlink=1" class="new" title="P38 mitogenom aktivirana proteinske kinaze (страница не постоји)">p38</a>, <a href="/w/index.php?title=C-fos&amp;action=edit&amp;redlink=1" class="new" title="C-fos (страница не постоји)">c-fos</a>, <a href="/w/index.php?title=C-jun&amp;action=edit&amp;redlink=1" class="new" title="C-jun (страница не постоји)">c-jun</a> i drugim.<sup id="cite_ref-endocrino_5-0" class="reference"><a href="#cite_note-endocrino-5"><span class="cite-bracket">&#91;</span>5<span class="cite-bracket">&#93;</span></a></sup> Funkcionalno, inhibicija intraćelijskog cAMP izražavanja skraćuje trajanje presinaptičkog akcionog potencijala, produžavajući kalijumske struje A-tipa, što je normalno inaktivirano nakon fosforilacije PKA-om. Ova inhibicija postaje izraženija pri aktivaciji CB<sub>1</sub> receptora da bi se ograničio ulaz kalcijuma u ćeliju. Pošto je presinaptički ulaz kalcijuma neophodan za otpuštanje vezikule, ova funkcija će umanjiti ulaz trasmitera u sinapse.<sup id="cite_ref-pmid11316486_1-1" class="reference"><a href="#cite_note-pmid11316486-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> Relativni doprinos svakog od ova dva inhibitorna mehanizam zavisi od varijanse izražavanja jonskih kanala u datom ćelijskom tipu. </p><p>CB<sub>1</sub> receptor se može modulisati putem <a href="/wiki/Alosterna_regulacija" title="Alosterna regulacija">alosternih</a> sintetičkih liganda<sup id="cite_ref-pmid16113085_6-0" class="reference"><a href="#cite_note-pmid16113085-6"><span class="cite-bracket">&#91;</span>6<span class="cite-bracket">&#93;</span></a></sup> u pozitivnom<sup id="cite_ref-pmid19226282_7-0" class="reference"><a href="#cite_note-pmid19226282-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup> i negativnom<sup id="cite_ref-pmid17592509_8-0" class="reference"><a href="#cite_note-pmid17592509-8"><span class="cite-bracket">&#91;</span>8<span class="cite-bracket">&#93;</span></a></sup> maniru. <i><a href="/wiki/In_vivo" title="In vivo">In vivo</a></i> izlaganje <a href="/wiki/Tetrahidrokanabinol" title="Tetrahidrokanabinol">THC</a> ligandu umanjuje <a href="/w/index.php?title=Dugotrajna_potencijacija&amp;action=edit&amp;redlink=1" class="new" title="Dugotrajna potencijacija (страница не постоји)">dugotrajnu potencijaciju</a> i dovodi do redukcije fosforilisanog <a href="/w/index.php?title=CREB&amp;action=edit&amp;redlink=1" class="new" title="CREB (страница не постоји)">CREB</a>.<sup id="cite_ref-neurochem_9-0" class="reference"><a href="#cite_note-neurochem-9"><span class="cite-bracket">&#91;</span>9<span class="cite-bracket">&#93;</span></a></sup> </p><p>Ukratko, aktivnost CB<sub>1</sub> receptora je spregnuta sa jonskim kanalima, na sledeći način:<sup id="cite_ref-pmid16570099_2-3" class="reference"><a href="#cite_note-pmid16570099-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> </p> <ul><li>Pozitivno sa unutrašnje ispravljajućih i A-tipom izvoznih kalijumskih kanala.</li> <li>Negativno sa D-tipom izvoznih kalijumskih kanala</li> <li>Negativno sa N-tipom i P/Q tipom kalcijumskih kanala.</li></ul> <div class="mw-heading mw-heading2"><h2 id="Izražavanje"><span id="Izra.C5.BEavanje"></span>Izražavanje</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Kanabinoidni_receptor_tip_1&amp;veaction=edit&amp;section=3" title="Уредите одељак „Izražavanje”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Kanabinoidni_receptor_tip_1&amp;action=edit&amp;section=3" title="Уреди извор одељка: Izražavanje"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>CB<sub>1</sub> receptor je kodiran genom <i>CNR1,</i><sup id="cite_ref-entrez_3-1" class="reference"><a href="#cite_note-entrez-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> lociranim na ljudskom hromozomu 6.<sup id="cite_ref-pmid11316486_1-2" class="reference"><a href="#cite_note-pmid11316486-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> Dve transkriptne varijante koje kodiraju različite izoforme su opisane za ovaj gen.<sup id="cite_ref-entrez_3-2" class="reference"><a href="#cite_note-entrez-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> CNR1 <a href="/wiki/%D0%A5%D0%BE%D0%BC%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%98%D0%B0_(%D0%B1%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%98%D0%B0)" title="Хомологија (биологија)">ortolozi</a><sup id="cite_ref-OrthoMaM_10-0" class="reference"><a href="#cite_note-OrthoMaM-10"><span class="cite-bracket">&#91;</span>10<span class="cite-bracket">&#93;</span></a></sup> su identifikovani kod većine <a href="/wiki/%D0%A1%D0%B8%D1%81%D0%B0%D1%80%D0%B8" title="Сисари">sisara</a>. </p><p>CB<sub>1</sub> receptor je izražen presinaptički na glutaminergičnim i GABAergičnim neuronima i efektivno deluje kao <a href="/w/index.php?title=Neuromodulator&amp;action=edit&amp;redlink=1" class="new" title="Neuromodulator (страница не постоји)">neuromodulator</a> koji inhibira otpuštanje <a href="/wiki/Glutamat" class="mw-redirect" title="Glutamat">glutamata</a> i <a href="/wiki/GABA" class="mw-redirect" title="GABA">GABA</a>.<sup id="cite_ref-pmid11316486_1-3" class="reference"><a href="#cite_note-pmid11316486-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> Višestruka administracija agonista može da dovede do internalizacije i/ili redukcije signalizacije receptora.<sup id="cite_ref-pmid16570099_2-4" class="reference"><a href="#cite_note-pmid16570099-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> </p><p><a href="/wiki/Inverzni_agonist" title="Inverzni agonist">Inverzni agonist</a> <a href="/wiki/MK-9470" title="MK-9470">MK-9470</a> omogućava formiranje <i>in vivo</i> slika distribucije CB<sub>1</sub> receptora u ljudskom mozgu pomoću <a href="/wiki/Pozitronska_emisiona_tomografija" title="Pozitronska emisiona tomografija">pozitronske emisione tomografije</a>.<sup id="cite_ref-pmid17535893_11-0" class="reference"><a href="#cite_note-pmid17535893-11"><span class="cite-bracket">&#91;</span>11<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Reference">Reference</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Kanabinoidni_receptor_tip_1&amp;veaction=edit&amp;section=4" title="Уредите одељак „Reference”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Kanabinoidni_receptor_tip_1&amp;action=edit&amp;section=4" title="Уреди извор одељка: Reference"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r28440201">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist reflist-columns references-column-width reflist-columns-2"> <ol class="references"> <li id="cite_note-pmid11316486-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid11316486_1-0"><sup><i><b>а</b></i></sup></a> <a href="#cite_ref-pmid11316486_1-1"><sup><i><b>б</b></i></sup></a> <a href="#cite_ref-pmid11316486_1-2"><sup><i><b>в</b></i></sup></a> <a href="#cite_ref-pmid11316486_1-3"><sup><i><b>г</b></i></sup></a></span> <span class="reference-text"><cite class="citation journal">Elphick, M. 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(2006). „Cannabinoid signalling”. <i>Life Sciences</i>. <b>78</b> (6): 549—563. <a href="/wiki/PMID" title="PMID">PMID</a>&#160;<a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16109430">16109430</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.lfs.2005.05.055">10.1016/j.lfs.2005.05.055</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3AKanabinoidni+receptor+tip+1&amp;rft.atitle=Cannabinoid+signalling&amp;rft.au=Molleman%2C+A.&amp;rft.aufirst=D.&amp;rft.aulast=Demuth&amp;rft.date=2006&amp;rft.genre=article&amp;rft.issue=6&amp;rft.jtitle=Life+Sciences&amp;rft.pages=549-563&amp;rft.volume=78&amp;rft_id=info%3Adoi%2F10.1016%2Fj.lfs.2005.05.055&amp;rft_id=info%3Apmid%2F16109430&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span></span> </li> <li id="cite_note-endocrino-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-endocrino_5-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Pagotto, U.; Marsicano, G.; Cota, D.; Lutz, B.; Pasquali, R. (2006). „The emerging role of the endocannabinoid system in endocrine regulation and energy balance”. <i>Endocrine Reviews</i>. <b>27</b> (1): 73—100. <a href="/wiki/PMID" title="PMID">PMID</a>&#160;<a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16306385">16306385</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1210%2Fer.2005-0009">10.1210/er.2005-0009</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3AKanabinoidni+receptor+tip+1&amp;rft.atitle=The+emerging+role+of+the+endocannabinoid+system+in+endocrine+regulation+and+energy+balance&amp;rft.au=Cota%2C+D.&amp;rft.au=Lutz%2C+B.&amp;rft.au=Marsicano%2C+G.&amp;rft.au=Pasquali%2C+R.&amp;rft.aufirst=U.&amp;rft.aulast=Pagotto&amp;rft.date=2006&amp;rft.genre=article&amp;rft.issue=1&amp;rft.jtitle=Endocrine+Reviews&amp;rft.pages=73-100&amp;rft.volume=27&amp;rft_id=info%3Adoi%2F10.1210%2Fer.2005-0009&amp;rft_id=info%3Apmid%2F16306385&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span> <span style="font-size:100%" class="error citation-comment">Пронађени су сувишни параметри: <code style="color:inherit; border:inherit; padding:inherit;">&#124;author2=</code> и <code style="color:inherit; border:inherit; padding:inherit;">&#124;last2=</code> (<a href="/wiki/%D0%9F%D0%BE%D0%BC%D0%BE%D1%9B:CS1_%D0%B3%D1%80%D0%B5%D1%88%D0%BA%D0%B5#redundant_parameters" title="Помоћ:CS1 грешке">помоћ</a>); </span><span style="font-size:100%" class="error citation-comment">Пронађени су сувишни параметри: <code style="color:inherit; border:inherit; padding:inherit;">&#124;author3=</code> и <code style="color:inherit; border:inherit; padding:inherit;">&#124;last3=</code> (<a href="/wiki/%D0%9F%D0%BE%D0%BC%D0%BE%D1%9B:CS1_%D0%B3%D1%80%D0%B5%D1%88%D0%BA%D0%B5#redundant_parameters" title="Помоћ:CS1 грешке">помоћ</a>); </span><span style="font-size:100%" class="error citation-comment">Пронађени су сувишни параметри: <code style="color:inherit; border:inherit; padding:inherit;">&#124;author4=</code> и <code style="color:inherit; border:inherit; padding:inherit;">&#124;last4=</code> (<a href="/wiki/%D0%9F%D0%BE%D0%BC%D0%BE%D1%9B:CS1_%D0%B3%D1%80%D0%B5%D1%88%D0%BA%D0%B5#redundant_parameters" title="Помоћ:CS1 грешке">помоћ</a>); </span><span style="font-size:100%" class="error citation-comment">Пронађени су сувишни параметри: <code style="color:inherit; border:inherit; padding:inherit;">&#124;author5=</code> и <code style="color:inherit; border:inherit; padding:inherit;">&#124;last5=</code> (<a href="/wiki/%D0%9F%D0%BE%D0%BC%D0%BE%D1%9B:CS1_%D0%B3%D1%80%D0%B5%D1%88%D0%BA%D0%B5#redundant_parameters" title="Помоћ:CS1 грешке">помоћ</a>)</span></span> </li> <li id="cite_note-pmid16113085-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid16113085_6-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Price MR, Baillie GL, Thomas A, Stevenson LA, Easson M, Goodwin R, McLean A, McIntosh L, Goodwin G, Walker G, Westwood P, Marrs J, Thomson F, Cowley P, Christopoulos A, Pertwee RG, Ross RA (2005). „Allosteric modulation of the cannabinoid CB1 receptor”. <i>Mol. Pharmacol</i>. <b>68</b> (5): 1484—95. <a href="/wiki/PMID" title="PMID">PMID</a>&#160;<a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16113085">16113085</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1124%2Fmol.105.016162">10.1124/mol.105.016162</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3AKanabinoidni+receptor+tip+1&amp;rft.atitle=Allosteric+modulation+of+the+cannabinoid+CB1+receptor&amp;rft.au=Baillie%2C+GL&amp;rft.au=Christopoulos%2C+A&amp;rft.au=Cowley%2C+P&amp;rft.au=Easson%2C+M&amp;rft.au=Goodwin%2C+G&amp;rft.au=Goodwin%2C+R&amp;rft.au=Marrs%2C+J&amp;rft.au=McIntosh%2C+L&amp;rft.au=McLean%2C+A&amp;rft.au=Pertwee%2C+RG&amp;rft.au=Ross%2C+RA&amp;rft.au=Stevenson%2C+LA&amp;rft.au=Thomas%2C+A&amp;rft.au=Thomson%2C+F&amp;rft.au=Walker%2C+G&amp;rft.au=Westwood%2C+P&amp;rft.aufirst=MR&amp;rft.aulast=Price&amp;rft.date=2005&amp;rft.genre=article&amp;rft.issue=5&amp;rft.jtitle=Mol.+Pharmacol.&amp;rft.pages=1484-95&amp;rft.volume=68&amp;rft_id=info%3Adoi%2F10.1124%2Fmol.105.016162&amp;rft_id=info%3Apmid%2F16113085&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span></span> </li> <li id="cite_note-pmid19226282-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid19226282_7-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Navarro HA, Howard JL, Pollard GT, Carroll FI (2009). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2697692">„Positive allosteric modulation of the human cannabinoid (CB1) receptor by RTI-371, a selective inhibitor of the dopamine transporter”</a>. <i>Br. 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Архивирано из <a rel="nofollow" class="external text" href="http://www.orthomam.univ-montp2.fr/orthomam/data/cds/detailMarkers/ENSG00000118432_CNR1.xml">оригинала</a> 22. 12. 2015. г<span class="reference-accessdate">. Приступљено <span class="nowrap">21. 7. 2012</span></span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3AKanabinoidni+receptor+tip+1&amp;rft.btitle=OrthoMaM+phylogenetic+marker%3A+CNR1+coding+sequence&amp;rft.genre=unknown&amp;rft_id=http%3A%2F%2Fwww.orthomam.univ-montp2.fr%2Forthomam%2Fdata%2Fcds%2FdetailMarkers%2FENSG00000118432_CNR1.xml&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;">&#160;</span></span></span> </li> <li id="cite_note-pmid17535893-11"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid17535893_11-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Burns, H. .; Laere, K. .; Sanabria-Bohórquez, S. .; Hamill, T. .; Bormans, G. .; Eng, W. .; Gibson, R. .; Ryan, C. .; Connolly, B. . (2007). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC1877985">„18FMK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor”</a>. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. <b>104</b> (23): 9800—9805. <a href="/wiki/Bibcode" title="Bibcode">Bibcode</a>:<a rel="nofollow" class="external text" href="http://adsabs.harvard.edu/abs/2007PNAS..104.9800B">2007PNAS..104.9800B</a>. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a>&#160;<span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC1877985">1877985</a>&#8239;<span typeof="mw:File"><span title="Слободан приступ"><img alt="Слободан приступ" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>. <a href="/wiki/PMID" title="PMID">PMID</a>&#160;<a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/17535893">17535893</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1073%2Fpnas.0703472104">10.1073/pnas.0703472104</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3AKanabinoidni+receptor+tip+1&amp;rft.atitle=18FMK-9470%2C+a+positron+emission+tomography+%28PET%29+tracer+for+in+vivo+human+PET+brain+imaging+of+the+cannabinoid-1+receptor&amp;rft.au=Bormans%2C+G.+.&amp;rft.au=Connolly%2C+B.+.&amp;rft.au=Eng%2C+W.+.&amp;rft.au=Gibson%2C+R.+.&amp;rft.au=Hamill%2C+T.+.&amp;rft.au=Laere%2C+K.+.&amp;rft.au=Ryan%2C+C.+.&amp;rft.au=Sanabria-Boh%C3%B3rquez%2C+S.+.&amp;rft.aufirst=H.+.&amp;rft.aulast=Burns&amp;rft.date=2007&amp;rft.genre=article&amp;rft.issue=23&amp;rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&amp;rft.pages=9800-9805&amp;rft.volume=104&amp;rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1877985&amp;rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1877985&amp;rft_id=info%3Abibcode%2F2007PNAS..104.9800B&amp;rft_id=info%3Adoi%2F10.1073%2Fpnas.0703472104&amp;rft_id=info%3Apmid%2F17535893&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span> <span style="font-size:100%" class="error citation-comment">Пронађени су сувишни параметри: <code style="color:inherit; border:inherit; padding:inherit;">&#124;author3=</code> и <code style="color:inherit; border:inherit; padding:inherit;">&#124;last3=</code> (<a href="/wiki/%D0%9F%D0%BE%D0%BC%D0%BE%D1%9B:CS1_%D0%B3%D1%80%D0%B5%D1%88%D0%BA%D0%B5#redundant_parameters" title="Помоћ:CS1 грешке">помоћ</a>); </span><span style="font-size:100%" class="error citation-comment">Пронађени су сувишни параметри: <code style="color:inherit; border:inherit; padding:inherit;">&#124;author4=</code> и <code style="color:inherit; border:inherit; padding:inherit;">&#124;last4=</code> (<a href="/wiki/%D0%9F%D0%BE%D0%BC%D0%BE%D1%9B:CS1_%D0%B3%D1%80%D0%B5%D1%88%D0%BA%D0%B5#redundant_parameters" title="Помоћ:CS1 грешке">помоћ</a>); </span><span style="font-size:100%" class="error citation-comment">Пронађени су сувишни параметри: <code style="color:inherit; border:inherit; padding:inherit;">&#124;author5=</code> и <code style="color:inherit; border:inherit; padding:inherit;">&#124;last5=</code> (<a href="/wiki/%D0%9F%D0%BE%D0%BC%D0%BE%D1%9B:CS1_%D0%B3%D1%80%D0%B5%D1%88%D0%BA%D0%B5#redundant_parameters" title="Помоћ:CS1 грешке">помоћ</a>); </span><span style="font-size:100%" class="error citation-comment">Пронађени су сувишни параметри: <code style="color:inherit; border:inherit; padding:inherit;">&#124;author6=</code> и <code style="color:inherit; border:inherit; padding:inherit;">&#124;last6=</code> (<a href="/wiki/%D0%9F%D0%BE%D0%BC%D0%BE%D1%9B:CS1_%D0%B3%D1%80%D0%B5%D1%88%D0%BA%D0%B5#redundant_parameters" title="Помоћ:CS1 грешке">помоћ</a>); </span><span style="font-size:100%" class="error citation-comment">Пронађени су сувишни параметри: <code style="color:inherit; border:inherit; padding:inherit;">&#124;author7=</code> и <code style="color:inherit; border:inherit; padding:inherit;">&#124;last7=</code> (<a href="/wiki/%D0%9F%D0%BE%D0%BC%D0%BE%D1%9B:CS1_%D0%B3%D1%80%D0%B5%D1%88%D0%BA%D0%B5#redundant_parameters" title="Помоћ:CS1 грешке">помоћ</a>); </span><span style="font-size:100%" class="error citation-comment">Пронађени су сувишни параметри: <code style="color:inherit; border:inherit; padding:inherit;">&#124;author8=</code> и <code style="color:inherit; border:inherit; padding:inherit;">&#124;last8=</code> (<a href="/wiki/%D0%9F%D0%BE%D0%BC%D0%BE%D1%9B:CS1_%D0%B3%D1%80%D0%B5%D1%88%D0%BA%D0%B5#redundant_parameters" title="Помоћ:CS1 грешке">помоћ</a>); </span><span style="font-size:100%" class="error citation-comment">Пронађени су сувишни параметри: <code style="color:inherit; border:inherit; padding:inherit;">&#124;author9=</code> и <code style="color:inherit; border:inherit; padding:inherit;">&#124;last9=</code> (<a href="/wiki/%D0%9F%D0%BE%D0%BC%D0%BE%D1%9B:CS1_%D0%B3%D1%80%D0%B5%D1%88%D0%BA%D0%B5#redundant_parameters" title="Помоћ:CS1 грешке">помоћ</a>); </span><span style="font-size:100%" class="error citation-comment"><code style="color:inherit; border:inherit; padding:inherit;">&#124;first10=</code> захтева <code style="color:inherit; border:inherit; padding:inherit;">&#124;last10=</code> у Authors list (<a href="/wiki/%D0%9F%D0%BE%D0%BC%D0%BE%D1%9B:CS1_%D0%B3%D1%80%D0%B5%D1%88%D0%BA%D0%B5#first_missing_last" title="Помоћ:CS1 грешке">помоћ</a>)</span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Literatura">Literatura</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Kanabinoidni_receptor_tip_1&amp;veaction=edit&amp;section=5" title="Уредите одељак „Literatura”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Kanabinoidni_receptor_tip_1&amp;action=edit&amp;section=5" title="Уреди извор одељка: Literatura"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r28440192">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin refbegin-columns references-column-count references-column-count-2" style="column-count: 2;"> <ul><li><cite class="citation journal">Oddi, S.; Spagnuolo, P.; Bari, M.; Dagostino, A.; MacCarrone, M. (2007). „Differential Modulation of Type 1 and Type 2 Cannabinoid Receptors along the Neuroimmune Axis”. <i>International review of neurobiology</i>. International Review of Neurobiology. <b>82</b>: 327—337. <a href="/wiki/Me%C4%91unarodni_standardni_broj_knjige" title="Međunarodni standardni broj knjige">ISBN</a>&#160;<a href="/wiki/%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%A8%D1%82%D0%B0%D0%BC%D0%BF%D0%B0%D0%BD%D0%B8_%D0%B8%D0%B7%D0%B2%D0%BE%D1%80%D0%B8/978-0-12-373989-6" title="Посебно:Штампани извори/978-0-12-373989-6">978-0-12-373989-6</a>. <a href="/wiki/PMID" title="PMID">PMID</a>&#160;<a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/17678969">17678969</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0074-7742%2807%2982017-4">10.1016/S0074-7742(07)82017-4</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3AKanabinoidni+receptor+tip+1&amp;rft.atitle=Differential+Modulation+of+Type+1+and+Type+2+Cannabinoid+Receptors+along+the+Neuroimmune+Axis&amp;rft.au=Bari%2C+M.&amp;rft.au=Dagostino%2C+A.&amp;rft.au=MacCarrone%2C+M.&amp;rft.au=Spagnuolo%2C+P.&amp;rft.aufirst=S.&amp;rft.aulast=Oddi&amp;rft.date=2007&amp;rft.genre=article&amp;rft.isbn=978-0-12-373989-6&amp;rft.jtitle=International+review+of+neurobiology&amp;rft.pages=327-337&amp;rft.volume=82&amp;rft_id=info%3Adoi%2F10.1016%2FS0074-7742%2807%2982017-4&amp;rft_id=info%3Apmid%2F17678969&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span></li> <li><cite class="citation journal">Gérard, C. M.; Mollereau; Vassart; Parmentier (1991). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC1151556">„Molecular cloning of a human cannabinoid receptor which is also expressed in testis”</a>. <i>The Biochemical journal</i>. <b>279</b> (1): 129—134. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a>&#160;<span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC1151556">1151556</a>&#8239;<span typeof="mw:File"><span title="Слободан приступ"><img alt="Слободан приступ" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>. <a href="/wiki/PMID" title="PMID">PMID</a>&#160;<a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/1718258">1718258</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3AKanabinoidni+receptor+tip+1&amp;rft.atitle=Molecular+cloning+of+a+human+cannabinoid+receptor+which+is+also+expressed+in+testis&amp;rft.au=Mollereau&amp;rft.au=Parmentier&amp;rft.au=Vassart&amp;rft.aufirst=C.+M.&amp;rft.aulast=G%C3%A9rard&amp;rft.date=1991&amp;rft.genre=article&amp;rft.issue=1&amp;rft.jtitle=The+Biochemical+journal&amp;rft.pages=129-134&amp;rft.volume=279&amp;rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1151556&amp;rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1151556&amp;rft_id=info%3Apmid%2F1718258&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span> <span style="font-size:100%" class="error citation-comment">Пронађени су сувишни параметри: <code style="color:inherit; border:inherit; padding:inherit;">&#124;author2=</code> и <code style="color:inherit; border:inherit; padding:inherit;">&#124;last2=</code> (<a href="/wiki/%D0%9F%D0%BE%D0%BC%D0%BE%D1%9B:CS1_%D0%B3%D1%80%D0%B5%D1%88%D0%BA%D0%B5#redundant_parameters" title="Помоћ:CS1 грешке">помоћ</a>); </span><span style="font-size:100%" class="error citation-comment">Пронађени су сувишни параметри: <code style="color:inherit; border:inherit; padding:inherit;">&#124;author3=</code> и <code style="color:inherit; border:inherit; padding:inherit;">&#124;last3=</code> (<a href="/wiki/%D0%9F%D0%BE%D0%BC%D0%BE%D1%9B:CS1_%D0%B3%D1%80%D0%B5%D1%88%D0%BA%D0%B5#redundant_parameters" title="Помоћ:CS1 грешке">помоћ</a>); </span><span style="font-size:100%" class="error citation-comment">Пронађени су сувишни параметри: <code style="color:inherit; border:inherit; padding:inherit;">&#124;author4=</code> и <code style="color:inherit; border:inherit; padding:inherit;">&#124;last4=</code> (<a href="/wiki/%D0%9F%D0%BE%D0%BC%D0%BE%D1%9B:CS1_%D0%B3%D1%80%D0%B5%D1%88%D0%BA%D0%B5#redundant_parameters" title="Помоћ:CS1 грешке">помоћ</a>)</span></li> <li><cite class="citation journal">MR, Hoehe; L, Caenazzo; MM, Martinez (1991). „Genetic and physical mapping of the human cannabinoid receptor gene to chromosome 6q14-q15”. <i>New Biol</i>. <b>3</b> (9): 880—5. <a href="/wiki/PMID" title="PMID">PMID</a>&#160;<a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/1931832">1931832</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3AKanabinoidni+receptor+tip+1&amp;rft.atitle=Genetic+and+physical+mapping+of+the+human+cannabinoid+receptor+gene+to+chromosome+6q14-q15&amp;rft.au=L%2C+Caenazzo&amp;rft.au=MM%2C+Martinez&amp;rft.aufirst=Hoehe&amp;rft.aulast=MR&amp;rft.date=1991&amp;rft.genre=article&amp;rft.issue=9&amp;rft.jtitle=New+Biol.&amp;rft.pages=880-5&amp;rft.volume=3&amp;rft_id=info%3Apmid%2F1931832&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span></li> <li><cite class="citation journal">LA, Matsuda; SJ, Lolait; MJ, Brownstein (1990). „Structure of a cannabinoid receptor and functional expression of the cloned cDNA”. <i>Nature</i>. <b>346</b> (6284): 561—4. <a href="/wiki/Bibcode" title="Bibcode">Bibcode</a>:<a rel="nofollow" class="external text" href="http://adsabs.harvard.edu/abs/1990Natur.346..561M">1990Natur.346..561M</a>. <a href="/wiki/PMID" title="PMID">PMID</a>&#160;<a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/2165569">2165569</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2F346561a0">10.1038/346561a0</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3AKanabinoidni+receptor+tip+1&amp;rft.atitle=Structure+of+a+cannabinoid+receptor+and+functional+expression+of+the+cloned+cDNA&amp;rft.au=MJ%2C+Brownstein&amp;rft.au=SJ%2C+Lolait&amp;rft.aufirst=Matsuda&amp;rft.aulast=LA&amp;rft.date=1990&amp;rft.genre=article&amp;rft.issue=6284&amp;rft.jtitle=Nature&amp;rft.pages=561-4&amp;rft.volume=346&amp;rft_id=info%3Abibcode%2F1990Natur.346..561M&amp;rft_id=info%3Adoi%2F10.1038%2F346561a0&amp;rft_id=info%3Apmid%2F2165569&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span></li> <li><cite class="citation journal">Gérard C, Mollereau C, Vassart G, Parmentier M (1991). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC332788">„Nucleotide sequence of a human cannabinoid receptor cDNA”</a>. <i>Nucleic Acids Res</i>. <b>18</b> (23): 7142. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a>&#160;<span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC332788">332788</a>&#8239;<span typeof="mw:File"><span title="Слободан приступ"><img alt="Слободан приступ" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>. <a href="/wiki/PMID" title="PMID">PMID</a>&#160;<a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/2263478">2263478</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fnar%2F18.23.7142">10.1093/nar/18.23.7142</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3AKanabinoidni+receptor+tip+1&amp;rft.atitle=Nucleotide+sequence+of+a+human+cannabinoid+receptor+cDNA&amp;rft.au=Mollereau%2C+C&amp;rft.au=Parmentier%2C+M&amp;rft.au=Vassart%2C+G&amp;rft.aufirst=C&amp;rft.aulast=G%C3%A9rard&amp;rft.date=1991&amp;rft.genre=article&amp;rft.issue=23&amp;rft.jtitle=Nucleic+Acids+Res.&amp;rft.pages=7142&amp;rft.volume=18&amp;rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC332788&amp;rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC332788&amp;rft_id=info%3Adoi%2F10.1093%2Fnar%2F18.23.7142&amp;rft_id=info%3Apmid%2F2263478&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span></li> <li><cite class="citation journal">D, Shire; 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Psychiatry</i>. <b>7</b> (5): 515—8. <a href="/wiki/PMID" title="PMID">PMID</a>&#160;<a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/12082570">12082570</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fsj.mp.4001029">10.1038/sj.mp.4001029</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3AKanabinoidni+receptor+tip+1&amp;rft.atitle=CNR1%2C+central+cannabinoid+receptor+gene%2C+associated+with+susceptibility+to+hebephrenic+schizophrenia&amp;rft.au=K%2C+Nakata&amp;rft.au=M%2C+Takaki&amp;rft.aufirst=Ujike&amp;rft.aulast=H&amp;rft.date=2002&amp;rft.genre=article&amp;rft.issue=5&amp;rft.jtitle=Mol.+Psychiatry&amp;rft.pages=515-8&amp;rft.volume=7&amp;rft_id=info%3Adoi%2F10.1038%2Fsj.mp.4001029&amp;rft_id=info%3Apmid%2F12082570&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span></li> <li><cite class="citation journal">Ho BY, Current L, Drewett JG (2002). „Role of intracellular loops of cannabinoid CB(1) receptor in functional interaction with G(alpha16)”. <i>FEBS Lett</i>. <b>522</b> (1–3): 130—4. <a href="/wiki/PMID" title="PMID">PMID</a>&#160;<a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/12095632">12095632</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0014-5793%2802%2902917-4">10.1016/S0014-5793(02)02917-4</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3AKanabinoidni+receptor+tip+1&amp;rft.atitle=Role+of+intracellular+loops+of+cannabinoid+CB%281%29+receptor+in+functional+interaction+with+G%28alpha16%29&amp;rft.au=Current%2C+L&amp;rft.au=Drewett%2C+JG&amp;rft.aufirst=BY&amp;rft.aulast=Ho&amp;rft.date=2002&amp;rft.genre=article&amp;rft.issue=1%E2%80%933&amp;rft.jtitle=FEBS+Lett.&amp;rft.pages=130-4&amp;rft.volume=522&amp;rft_id=info%3Adoi%2F10.1016%2FS0014-5793%2802%2902917-4&amp;rft_id=info%3Apmid%2F12095632&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span></li> <li><cite class="citation journal">I, Matias; P, Pochard; P, Orlando (2002). „Presence and regulation of the endocannabinoid system in human dendritic cells”. <i>Eur. J. Biochem</i>. <b>269</b> (15): 3771—8. <a href="/wiki/PMID" title="PMID">PMID</a>&#160;<a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/12153574">12153574</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1046%2Fj.1432-1033.2002.03078.x">10.1046/j.1432-1033.2002.03078.x</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3AKanabinoidni+receptor+tip+1&amp;rft.atitle=Presence+and+regulation+of+the+endocannabinoid+system+in+human+dendritic+cells&amp;rft.au=P%2C+Orlando&amp;rft.au=P%2C+Pochard&amp;rft.aufirst=Matias&amp;rft.aulast=I&amp;rft.date=2002&amp;rft.genre=article&amp;rft.issue=15&amp;rft.jtitle=Eur.+J.+Biochem.&amp;rft.pages=3771-8&amp;rft.volume=269&amp;rft_id=info%3Adoi%2F10.1046%2Fj.1432-1033.2002.03078.x&amp;rft_id=info%3Apmid%2F12153574&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="Spoljašnje_veze"><span id="Spolja.C5.A1nje_veze"></span>Spoljašnje veze</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Kanabinoidni_receptor_tip_1&amp;veaction=edit&amp;section=6" title="Уредите одељак „Spoljašnje veze”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Kanabinoidni_receptor_tip_1&amp;action=edit&amp;section=6" title="Уреди извор одељка: Spoljašnje veze"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><cite class="citation web"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20120305214535/http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=2205">„Cannabinoid Receptors: CB<sub>1</sub>”</a>. <i>IUPHAR Database of Receptors and Ion Channels</i>. International Union of Basic and Clinical Pharmacology. Архивирано из <a rel="nofollow" class="external text" href="http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=2205">оригинала</a> 05. 03. 2012. г.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3AKanabinoidni+receptor+tip+1&amp;rft.atitle=Cannabinoid+Receptors%3A+CB%3Csub%3E1%3C%2Fsub%3E&amp;rft.genre=unknown&amp;rft.jtitle=IUPHAR+Database+of+Receptors+and+Ion+Channels&amp;rft_id=http%3A%2F%2Fwww.iuphar-db.org%2FGPCR%2FReceptorDisplayForward%3FreceptorID%3D2205&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span></li></ul> <div style="clear:both;"></div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r25469611">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output 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s G proteinom">receptori spregnuti s G proteinom</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:left; background-color: AntiqueWhite"><a href="/wiki/Rodopsinu-sli%C4%8Dni_receptori" title="Rodopsinu-slični receptori">Klasa A</a>: <a href="/wiki/Rodopsin" title="Rodopsin">Rodopsinu</a> slični</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:8em;"><a href="/wiki/%D0%9D%D0%B5%D1%83%D1%80%D0%BE%D1%82%D1%80%D0%B0%D0%BD%D1%81%D0%BC%D0%B8%D1%82%D0%B5%D1%80" title="Неуротрансмитер">Neurotransmiter</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;"><a href="/wiki/Adrenergi%C4%8Dki_receptor" title="Adrenergički receptor">Adrenergički</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;;background-color: AntiqueWhite;"><div style="padding:0 0.25em"><a href="/wiki/Alfa-1_adrenergi%C4%8Dki_receptor" title="Alfa-1 adrenergički receptor">α1</a> (<a href="/wiki/Alfa-1A_adrenergi%C4%8Dki_receptor" title="Alfa-1A adrenergički receptor">A</a>, <a href="/wiki/Alfa-1B_adrenergi%C4%8Dki_receptor" title="Alfa-1B adrenergički receptor">B</a>, <a href="/wiki/Alfa-1D_adrenergi%C4%8Dki_receptor" title="Alfa-1D adrenergički receptor">D</a>)&#160;&#8226;&#32; <a href="/wiki/Alfa-2_adrenergi%C4%8Dki_receptor" title="Alfa-2 adrenergički receptor">α2</a> (<a href="/wiki/Alfa-2A_adrenergi%C4%8Dki_receptor" title="Alfa-2A adrenergički receptor">A</a>, <a href="/wiki/Alfa-2B_adrenergi%C4%8Dki_receptor" title="Alfa-2B adrenergički receptor">B</a>, <a href="/wiki/Alfa-2C_adrenergi%C4%8Dki_receptor" title="Alfa-2C adrenergički receptor">C</a>)&#160;&#8226;&#32; <a href="/wiki/Beta-1_adrenergi%C4%8Dki_receptor" title="Beta-1 adrenergički receptor">β1</a>&#160;&#8226;&#32; <a href="/wiki/Beta-2_adrenergi%C4%8Dki_receptor" title="Beta-2 adrenergički receptor">β2</a>&#160;&#8226;&#32; <a href="/wiki/Beta-3_adrenergi%C4%8Dki_receptor" title="Beta-3 adrenergički receptor">β3</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;"><a href="/wiki/Purinski_receptor" title="Purinski receptor">Purinski</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"><a href="/wiki/Adenozinski_receptor" title="Adenozinski receptor">Adenozinski</a> (<a href="/wiki/Adenozinski_A1_receptor" title="Adenozinski A1 receptor">A1</a>, <a href="/wiki/Adenozinski_A2A_receptor" title="Adenozinski A2A receptor">A2A</a>, <a href="/wiki/Adenozinski_A2B_receptor" title="Adenozinski A2B receptor">A2B</a>, <a href="/wiki/Adenozinski_A3_receptor" title="Adenozinski A3 receptor">A3</a>)&#160;&#8226;&#32; <a href="/wiki/P2Y_receptor" title="P2Y receptor">P2Y</a> (<a href="/wiki/P2RY1" title="P2RY1">1</a>, <a href="/wiki/P2RY2" title="P2RY2">2</a>, <a href="/wiki/P2RY4" title="P2RY4">4</a>, <a href="/wiki/LPAR6" title="LPAR6">5</a>, <a href="/wiki/P2RY6" title="P2RY6">6</a>, <a href="/wiki/P2RY8" title="P2RY8">8</a>, <a href="/wiki/GPR23" class="mw-redirect" title="GPR23">9</a>, <a href="/wiki/P2RY10" title="P2RY10">10</a>, <a href="/wiki/P2RY11" title="P2RY11">11</a>, <a href="/wiki/P2Y12" title="P2Y12">12</a>, <a href="/wiki/P2RY13" title="P2RY13">13</a>, <a href="/wiki/P2RY14" title="P2RY14">14</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;"><a href="/wiki/5-HT_receptor" title="5-HT receptor">Serotoninski</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;;background-color: AntiqueWhite;"><div style="padding:0 0.25em"><i>(svi osim 5-HT3)</i> <a href="/wiki/5-HT1_receptor" title="5-HT1 receptor">5-HT1</a> (<a href="/wiki/5-HT1A_receptor" title="5-HT1A receptor">A</a>, <a href="/wiki/5-HT1B_receptor" title="5-HT1B receptor">B</a>, <a href="/wiki/5-HT1D_receptor" title="5-HT1D receptor">D</a>, <a href="/wiki/5-HT1E_receptor" title="5-HT1E receptor">E</a>, <a href="/wiki/5-HT1F_receptor" title="5-HT1F receptor">F</a>)&#160;&#8226;&#32; <a href="/wiki/5-HT2_receptor" title="5-HT2 receptor">5-HT2</a> (<a href="/wiki/5-HT2A_receptor" title="5-HT2A receptor">A</a>, <a href="/wiki/5-HT2B_receptor" title="5-HT2B receptor">B</a>, <a href="/wiki/5-HT2C_receptor" title="5-HT2C receptor">C</a>)&#160;&#8226;&#32; <i>5-HT</i> (<a href="/wiki/5-HT4_receptor" title="5-HT4 receptor">4</a>, <a href="/wiki/5-HT5A_receptor" title="5-HT5A receptor">5A</a>, <a href="/wiki/5-HT6_receptor" title="5-HT6 receptor">6</a>, <a href="/wiki/5-HT7_receptor" title="5-HT7 receptor">7</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;">Drugi</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"><a href="/wiki/Muskarinski_acetilholinski_receptor" title="Muskarinski acetilholinski receptor">Acetilholin</a> (<a href="/wiki/Muskarinski_acetilholinski_receptor_M1" title="Muskarinski acetilholinski receptor M1">M1</a>, <a href="/wiki/Muskarinski_acetilholinski_receptor_M2" title="Muskarinski acetilholinski receptor M2">M2</a>, <a href="/wiki/Muskarinski_acetilholinski_receptor_M3" title="Muskarinski acetilholinski receptor M3">M3</a>, <a href="/wiki/Muskarinski_acetilholinski_receptor_M4" title="Muskarinski acetilholinski receptor M4">M4</a>, <a href="/wiki/Muskarinski_acetilholinski_receptor_M5" title="Muskarinski acetilholinski receptor M5">M5</a>)&#160;&#8226;&#32; <a href="/wiki/Dopaminski_receptor" title="Dopaminski receptor">Dopamin</a> (<a href="/wiki/Dopaminski_receptor_D1" title="Dopaminski receptor D1">D1</a>, <a href="/wiki/Dopaminski_receptor_D2" title="Dopaminski receptor D2">D2</a>, <a href="/wiki/Dopaminski_receptor_D3" title="Dopaminski receptor D3">D3</a>, <a href="/wiki/Dopaminski_receptor_D4" title="Dopaminski receptor D4">D4</a>, <a href="/wiki/Dopaminski_receptor_D5" title="Dopaminski receptor D5">D5</a>)&#160;&#8226;&#32; <a href="/wiki/Histaminski_receptor" title="Histaminski receptor">Histamin</a> (<a href="/wiki/Histaminski_H1_receptor" title="Histaminski H1 receptor">H1</a>, <a href="/wiki/Histaminski_H2_receptor" title="Histaminski H2 receptor">H2</a>, <a href="/wiki/Histaminski_H3_receptor" title="Histaminski H3 receptor">H3</a>, <a href="/wiki/Histaminski_H4_receptor" title="Histaminski H4 receptor">H4</a>)&#160;&#8226;&#32; <a href="/wiki/Melatoninski_receptor" title="Melatoninski receptor">Melatonin</a> (<a href="/wiki/Melatoninski_receptor_1A" title="Melatoninski receptor 1A">1A</a>, <a href="/wiki/Melatoninski_receptor_1B" title="Melatoninski receptor 1B">1B</a>, <a href="/wiki/Melatoninski_receptor_1C" title="Melatoninski receptor 1C">1C</a>)&#160;&#8226;&#32; <a href="/wiki/Trag_amin-asocirani_receptor" title="Trag amin-asocirani receptor">TAAR</a> (<a href="/wiki/TAAR1" title="TAAR1">1</a>, <a href="/wiki/TAAR2" title="TAAR2">2</a>, <a href="/wiki/TAAR3" title="TAAR3">3</a>, <a href="/wiki/TAAR5" title="TAAR5">5</a>, <a href="/wiki/TAAR6" title="TAAR6">6</a>, <a href="/wiki/TAAR8" title="TAAR8">8</a>, <a href="/wiki/TAAR9" title="TAAR9">9</a>)</div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:8em;">Metaboliti i<br />signalni molekuli</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;"><a href="/wiki/Eikozanoidni_receptor" title="Eikozanoidni receptor">Eikozanoidni</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;;background-color: AntiqueWhite;"><div style="padding:0 0.25em"><i>CysLT</i> (<a href="/wiki/Cisteinil_leukotrienski_receptor_1" title="Cisteinil leukotrienski receptor 1">1</a>, <a href="/wiki/Cisteinil_leukotrienski_receptor_2" title="Cisteinil leukotrienski receptor 2">2</a>)&#160;&#8226;&#32; <a href="/wiki/Leukotrien_B4" title="Leukotrien B4">LTB4</a> (<a href="/wiki/Leukotrienski_B4_receptor" title="Leukotrienski B4 receptor">1</a>, <a href="/wiki/Leukotrienski_B4_receptor_2" title="Leukotrienski B4 receptor 2">2</a>)&#160;&#8226;&#32; <a href="/wiki/Formil_peptidni_receptor_2" title="Formil peptidni receptor 2"> FPRL1</a>&#160;&#8226;&#32; <a href="/wiki/Oksoeikozanoidni_receptor_1" title="Oksoeikozanoidni receptor 1">OXE</a>&#160;&#8226;&#32; <a href="/wiki/Prostaglandinski_receptor" title="Prostaglandinski receptor">Prostaglandin</a> (<i>DP</i> (<a href="/wiki/Prostaglandinski_D2_receptor" title="Prostaglandinski D2 receptor">1</a>, <a href="/wiki/GPR44" title="GPR44">2</a>), <i>EP</i> (<a href="/wiki/EP1_receptor" title="EP1 receptor">1</a>, <a href="/wiki/Prostaglandinski_E2_receptor" title="Prostaglandinski E2 receptor">2</a>, <a href="/wiki/Prostaglandinski_E_receptor_3" title="Prostaglandinski E receptor 3">3</a>, <a href="/wiki/EP4_receptor" title="EP4 receptor">4</a>), <a href="/wiki/Prostaglandinski_F_receptor" title="Prostaglandinski F receptor">FP</a>)&#160;&#8226;&#32; <a href="/wiki/Prostaciklinski_receptor" title="Prostaciklinski receptor">Prostaciklin</a>&#160;&#8226;&#32; <a href="/wiki/Tromboksanski_receptor" title="Tromboksanski receptor"> Tromboksan</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;">Drugi</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"><a href="/wiki/Receptor_%C5%BEu%C4%8Dne_kiseline" title="Receptor žučne kiseline">Žučna kiselina</a>&#160;&#8226;&#32; <a href="/wiki/Kanabinoidni_receptor" title="Kanabinoidni receptor">Kanabinoidni</a> (<a class="mw-selflink selflink">CB1</a>, <a href="/wiki/Kanabinoidni_receptor_2" title="Kanabinoidni receptor 2">CB2</a>, <i>GPR</i> (<a href="/wiki/GPR18" title="GPR18">18</a>, <a href="/wiki/GPR55" title="GPR55">55</a>, <a href="/wiki/GPR119" title="GPR119">119</a>))&#160;&#8226;&#32; <a href="/wiki/GPR183" title="GPR183">EBI2</a>&#160;&#8226;&#32; <a href="/wiki/GPR30" title="GPR30">Estrogen</a>&#160;&#8226;&#32; <a href="/wiki/Receptor_slobodnih_masnih_kiselina" title="Receptor slobodnih masnih kiselina">Slobodna masna kiselina</a> (<a href="/wiki/Receptor_slobodnih_masnih_kiselina_1" title="Receptor slobodnih masnih kiselina 1">1</a>, <a href="/wiki/Receptor_slobodnih_masnih_kiselina_2" title="Receptor slobodnih masnih kiselina 2">2</a>, <a href="/wiki/Receptor_slobodnih_masnih_kiselina_3" title="Receptor slobodnih masnih kiselina 3">3</a>, <a href="/wiki/GPR42" title="GPR42">4</a>)&#160;&#8226;&#32; <a href="/wiki/GPR81" title="GPR81">Laktat</a>&#160;&#8226;&#32;<a href="/wiki/Lizofosfatidna_kiselina" title="Lizofosfatidna kiselina">Lizofosfatidna kiselina</a> (<a href="/wiki/LPAR1" title="LPAR1">1</a>, <a href="/wiki/LPAR2" title="LPAR2">2</a>, <a href="/wiki/LPAR3" title="LPAR3">3</a>, <a href="/wiki/LPAR4" title="LPAR4">4</a>, <a href="/wiki/LPAR5" title="LPAR5">5</a>, <a href="/wiki/LPAR6" title="LPAR6">6</a>)&#160;&#8226;&#32;<a href="/wiki/Lizofosfolipidni_receptor" title="Lizofosfolipidni receptor">Lizofosfolipid</a> (<a href="/wiki/S1PR1" title="S1PR1">1</a>, <a href="/wiki/LPAR1" title="LPAR1">2</a>, <a href="/wiki/S1PR3" title="S1PR3">3</a>, <a href="/wiki/LPAR2" title="LPAR2">4</a>, <a href="/wiki/S1PR2" title="S1PR2">5</a>, <a href="/wiki/S1PR4" title="S1PR4">6</a>, <a href="/wiki/LPAR3" title="LPAR3">7</a>, <a href="/wiki/S1PR5" title="S1PR5">8</a>)&#160;&#8226;&#32; <i><a href="/wiki/%D0%9D%D0%B8%D0%B0%D1%86%D0%B8%D0%BD" title="Ниацин">Niacin</a></i> (<a href="/wiki/Niacinski_receptor_1" title="Niacinski receptor 1">1</a>, <a href="/wiki/Niacinski_receptor_2" title="Niacinski receptor 2">2</a>)&#160;&#8226;&#32; <a href="/wiki/OXGR1" title="OXGR1">Oksoglutarat</a>&#160;&#8226;&#32; <a href="/wiki/Receptor_trombocit_aktiviraju%C4%87eg_faktora" title="Receptor trombocit aktivirajućeg faktora">PAF</a>&#160;&#8226;&#32; <a href="/wiki/Sfingozin-1-fosfat" title="Sfingozin-1-fosfat">Sfingozin-1-fosfat</a> (<a href="/wiki/S1PR1" title="S1PR1">1</a>, <a href="/wiki/S1PR2" title="S1PR2">2</a>, <a href="/wiki/S1PR3" title="S1PR3">3</a>, <a href="/wiki/S1PR4" title="S1PR4">4</a>, <a href="/wiki/S1PR5" title="S1PR5">5</a>)&#160;&#8226;&#32; <a href="/wiki/SUCNR1" title="SUCNR1">Sukcinat</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:8em;">Peptid</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;"><a href="/wiki/GPCR_neuropeptidni_receptor" title="GPCR neuropeptidni receptor">Neuropeptidni</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;;background-color: AntiqueWhite;"><div style="padding:0 0.25em"><a href="/wiki/Neuropeptidni_B/W_receptor" title="Neuropeptidni B/W receptor">B/W</a> (<a href="/wiki/Neuropeptidni_B/W_receptor_1" title="Neuropeptidni B/W receptor 1">1</a>, <a href="/wiki/Neuropeptidni_B/W_receptor_2" title="Neuropeptidni B/W receptor 2">2</a>)&#160;&#8226;&#32; <a href="/wiki/Neuropeptidni_FF_receptor" title="Neuropeptidni FF receptor">FF</a> (<a href="/wiki/Neuropeptidni_FF_receptor_1" title="Neuropeptidni FF receptor 1">1</a>, <a href="/wiki/Neuropeptidni_FF_receptor_2" title="Neuropeptidni FF receptor 2">2</a>)&#160;&#8226;&#32; <a href="/wiki/Neuropeptidni_S_receptor" title="Neuropeptidni S receptor">S</a>&#160;&#8226;&#32; <a href="/wiki/Neuropeptidni_Y_receptor" title="Neuropeptidni Y receptor">Y</a> (<a href="/wiki/Neuropeptidni_Y_receptor_Y1" title="Neuropeptidni Y receptor Y1">1</a>, <a href="/wiki/Neuropeptidni_Y_receptor_Y2" title="Neuropeptidni Y receptor Y2">2</a>, <a href="/wiki/Pankreasni_polipeptidni_receptor_1" title="Pankreasni polipeptidni receptor 1">4</a>, <a href="/wiki/Neuropeptidni_Y_receptor_Y5" title="Neuropeptidni Y receptor Y5">5</a>)&#160;&#8226;&#32; <i>Neuromedin</i> (<a href="/wiki/Neuromedinski_B_receptor" title="Neuromedinski B receptor">B</a>, <a href="/wiki/Neuromedinski_U_receptor" title="Neuromedinski U receptor">U</a> (<a href="/wiki/Neuromedinski_U_receptor_1" title="Neuromedinski U receptor 1">1</a>, <a href="/wiki/Neuromedinski_U_receptor_2" title="Neuromedinski U receptor 2">2</a>))&#160;&#8226;&#32; <a href="/wiki/Neurotenzinski_receptor" title="Neurotenzinski receptor">Neurotenzin</a> (<a href="/wiki/Neurotenzinski_receptor_1" title="Neurotenzinski receptor 1">1</a>, <a href="/wiki/Neurotenzinski_receptor_2" title="Neurotenzinski receptor 2">2</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;">Drugi</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"><a href="/wiki/Anafilatoksinski_receptori" title="Anafilatoksinski receptori"> Anafilatoksin</a> (<a href="/wiki/C3a_receptor" title="C3a receptor">C3a</a>, <a href="/wiki/C5a_receptor" title="C5a receptor">C5a</a>)&#160;&#8226;&#32; <a href="/wiki/Angiotenzinski_receptor" title="Angiotenzinski receptor">Angiotenzin</a> (<a href="/wiki/AGTR1" title="AGTR1">1</a>, <a href="/wiki/AGTR2" title="AGTR2">2</a>)&#160;&#8226;&#32; <a href="/wiki/Apelinski_receptor" title="Apelinski receptor">Apelin</a>&#160;&#8226;&#32; <a href="/wiki/Bombezinski_receptor" title="Bombezinski receptor">Bombezin</a> (<a href="/wiki/Bombezinu-sli%C4%8Dan_receptor_3" title="Bombezinu-sličan receptor 3">BRS3</a>, <a href="/wiki/Gastrin-osloba%C4%91aju%C4%87i_peptidni_receptor" title="Gastrin-oslobađajući peptidni receptor">GRPR</a>, <a href="/wiki/Neuromedinski_B_receptor" title="Neuromedinski B receptor">NMBR</a>)&#160;&#8226;&#32; <a href="/wiki/Bradikininski_receptor" title="Bradikininski receptor">Bradikinin</a> (<a href="/wiki/Bradikininski_receptor_B1" title="Bradikininski receptor B1">B1</a>, <a href="/wiki/Bradikininski_receptor_B2" title="Bradikininski receptor B2">B2</a>)&#160;&#8226;&#32; <a href="/wiki/Hemokinski_receptor" title="Hemokinski receptor">Hemokin</a>&#160;&#8226;&#32; <a href="/wiki/Holecistokininski_receptor" title="Holecistokininski receptor">Holecistokinin</a> (<a href="/wiki/Holecistokininski_receptor_A" title="Holecistokininski receptor A">A</a>, <a href="/wiki/Holecistokininski_receptor_B" title="Holecistokininski receptor B">B</a>)&#160;&#8226;&#32; <a href="/wiki/Endotelinski_receptor" title="Endotelinski receptor">Endotelin</a> (<a href="/wiki/Endotelinski_receptor_tip_A" title="Endotelinski receptor tip A">A</a>, <a href="/wiki/Endotelinski_receptor_tip_B" title="Endotelinski receptor tip B">B</a>)&#160;&#8226;&#32; <a href="/wiki/Formil_peptidni_receptor" title="Formil peptidni receptor">Formil peptid</a> (<a href="/wiki/Formil_peptidni_receptor_1" title="Formil peptidni receptor 1">1</a>, <a href="/wiki/Formil_peptidni_receptor_2" title="Formil peptidni receptor 2">2</a>, <a href="/wiki/Formil_peptidni_receptor_3" title="Formil peptidni receptor 3">3</a>)&#160;&#8226;&#32; <a href="/wiki/FSH-receptor" title="FSH-receptor">FSH</a>&#160;&#8226;&#32; <a href="/wiki/Galaninski_receptor" title="Galaninski receptor">Galanin</a> (<a href="/wiki/Galaninski_receptor_1" title="Galaninski receptor 1">1</a>, <a href="/wiki/Galaninski_receptor_2" title="Galaninski receptor 2">2</a>, <a href="/wiki/Galaninski_receptor_3" title="Galaninski receptor 3">3</a>)&#160;&#8226;&#32; <a href="/wiki/GHB_receptor" title="GHB receptor">GHB receptor</a>&#160;&#8226;&#32; <a href="/wiki/Gonadotropin-osloba%C4%91aju%C4%87i_hormon_receptor" title="Gonadotropin-oslobađajući hormon receptor">Gonadotropin-oslobađajući hormon</a> (<a href="/wiki/GNRHR" title="GNRHR">1</a>, <a href="/wiki/GNRHR2" title="GNRHR2">2</a>)&#160;&#8226;&#32; <a href="/wiki/Hormon_rasta_osloba%C4%91aju%C4%87i_receptor" class="mw-redirect" title="Hormon rasta oslobađajući receptor">Grelin</a>&#160;&#8226;&#32; <a href="/wiki/KISS1R" title="KISS1R"> Kispeptin</a>&#160;&#8226;&#32; <a href="/wiki/LHCGR" title="LHCGR">Luteinizirajući hormon/horiogonadotropin</a>&#160;&#8226;&#32; <a href="/wiki/MAS1_onkogen" title="MAS1 onkogen">MAS</a> (<a href="/wiki/MAS1" title="MAS1">1</a>, <a href="/wiki/MAS1L" title="MAS1L">1L</a>, <a href="/wiki/MRGPRD" title="MRGPRD">D</a>, <a href="/wiki/MRGPRE" title="MRGPRE">E</a>, <a href="/wiki/MRGPRF" title="MRGPRF">F</a>, <a href="/wiki/MRGPRG" title="MRGPRG">G</a>, <a href="/wiki/MRGPRX1" title="MRGPRX1">X1</a>, <a href="/wiki/MRGPRX2" title="MRGPRX2">X2</a>, <a href="/wiki/MRGPRX3" title="MRGPRX3">X3</a>, <a href="/wiki/MRGPRX4" title="MRGPRX4">X4</a>)&#160;&#8226;&#32; <a href="/wiki/Melanokortinski_receptor" title="Melanokortinski receptor">Melanokortin</a> (<a href="/wiki/Melanokortinski_1_receptor" title="Melanokortinski 1 receptor">1</a>, <a href="/wiki/ACTH_receptor" title="ACTH receptor">2</a>, <a href="/wiki/Melanokortinski_3_receptor" title="Melanokortinski 3 receptor">3</a>, <a href="/wiki/Melanokortinski_4_receptor" title="Melanokortinski 4 receptor">4</a>, <a href="/wiki/Melanokortinski_5_receptor" title="Melanokortinski 5 receptor">5</a>)&#160;&#8226;&#32; <a href="/wiki/Melanin-koncentriraju%C4%87i_hormonski_receptor" title="Melanin-koncentrirajući hormonski receptor">MCHR</a> (<a href="/wiki/Melanin-koncentriraju%C4%87i_hormonski_receptor_1" title="Melanin-koncentrirajući hormonski receptor 1">1</a>, <a href="/wiki/Melanin-koncentriraju%C4%87i_hormonski_receptor_2" title="Melanin-koncentrirajući hormonski receptor 2">2</a>)&#160;&#8226;&#32; <a href="/wiki/Motilin_receptor" title="Motilin receptor">Motilin</a>&#160;&#8226;&#32; <a href="/wiki/Opioidni_receptor" title="Opioidni receptor">Opioidni</a> (<a href="/wiki/Delta_opioidni_receptor" title="Delta opioidni receptor">δ</a>, <a href="/wiki/Kapa_opioidni_receptor" title="Kapa opioidni receptor">κ</a>, <a href="/wiki/Mi_opioidni_receptor" title="Mi opioidni receptor">μ</a>, <a href="/wiki/Nociceptinski_receptor" title="Nociceptinski receptor">Nociceptin</a> &amp; <a href="/wiki/OGFr" title="OGFr">ζ</a>, ali ne <a href="/wiki/Sigma_receptor" title="Sigma receptor">σ</a>)&#160;&#8226;&#32; <a href="/wiki/Oreksinski_receptor" title="Oreksinski receptor">Oreksin</a> (<a href="/wiki/Oreksinski_receptor_1" title="Oreksinski receptor 1">1</a>, <a href="/wiki/Oreksinski_receptor_2" title="Oreksinski receptor 2">2</a>)&#160;&#8226;&#32; <a href="/wiki/Oksitocinski_receptor" title="Oksitocinski receptor">Oksitocin</a>&#160;&#8226;&#32; <a href="/wiki/Prokineticinski_receptor" title="Prokineticinski receptor">Prokineticin</a> (<a href="/wiki/Prokineticinski_receptor_1" title="Prokineticinski receptor 1">1</a>, <a href="/wiki/Prokineticinski_receptor_2" title="Prokineticinski receptor 2">2</a>)&#160;&#8226;&#32; <a href="/wiki/PRRP" title="PRRP">Prolaktin-oslobađajući peptid</a>&#160;&#8226;&#32; <a href="/wiki/Relaksinski_receptor" title="Relaksinski receptor">Relaksin</a> (<a href="/wiki/RXFP1" title="RXFP1">1</a>, <a href="/wiki/RXFP2" title="RXFP2">2</a>, <a href="/wiki/RXFP3" title="RXFP3">3</a>, <a href="/wiki/RXFP4" title="RXFP4">4</a>)&#160;&#8226;&#32; <a href="/wiki/Somatostatinski_receptor" title="Somatostatinski receptor">Somatostatin</a> (<a href="/wiki/Somatostatinski_receptor_1" title="Somatostatinski receptor 1">1</a>, <a href="/wiki/Somatostatinski_receptor_2" title="Somatostatinski receptor 2">2</a>, <a href="/wiki/Somatostatinski_receptor_3" title="Somatostatinski receptor 3">3</a>, <a href="/wiki/Somatostatinski_receptor_4" title="Somatostatinski receptor 4">4</a>, <a href="/wiki/Somatostatinski_receptor_5" title="Somatostatinski receptor 5">5</a>)&#160;&#8226;&#32; <a href="/wiki/Tahikininski_receptor" title="Tahikininski receptor">Tahikinin</a> (<a href="/wiki/Tahikininski_receptor_1" title="Tahikininski receptor 1">1</a>, <a href="/wiki/Tahikininski_receptor_2" title="Tahikininski receptor 2">2</a>, <a href="/wiki/Tahikininski_receptor_3" title="Tahikininski receptor 3">3</a>)&#160;&#8226;&#32; <a href="/wiki/Tirotropinski_receptor" title="Tirotropinski receptor">Tirotropin</a>&#160;&#8226;&#32; <a href="/wiki/TRHR" title="TRHR">Tirotropin-oslobađajući hormon</a>&#160;&#8226;&#32; <a href="/wiki/Urotenzin-II_receptor" title="Urotenzin-II receptor">Urotenzin-II</a>&#160;&#8226;&#32; <a href="/wiki/Vazopresinski_receptor" title="Vazopresinski receptor">Vazopresin</a> (<a href="/wiki/Arginin_vazopresinski_receptor_1A" title="Arginin vazopresinski receptor 1A">1A</a>, <a href="/wiki/Arginin_vazopresinski_receptor_1B" title="Arginin vazopresinski receptor 1B">1B</a>, <a href="/wiki/Arginin_vazopresinski_receptor_2" title="Arginin vazopresinski receptor 2">2</a>)</div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:8em;">Razno</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;"><a href="/wiki/Orfan_receptor" title="Orfan receptor">Orfan</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;;background-color: AntiqueWhite;"><div style="padding:0 0.25em"><i>GPR</i> (<a href="/wiki/GPR1" title="GPR1">1</a>, <a href="/wiki/GPR3" title="GPR3">3</a>, <a href="/wiki/GPR4" title="GPR4">4</a>, <a href="/wiki/GPR6" title="GPR6">6</a>, <a href="/wiki/GPR12" title="GPR12">12</a>, <a href="/wiki/GPR15" title="GPR15">15</a>, <a href="/wiki/GPR17" title="GPR17">17</a>, <a href="/wiki/GPR18" title="GPR18">18</a>, <a href="/wiki/GPR19" title="GPR19">19</a>, <a href="/wiki/GPR20" title="GPR20">20</a>, <a href="/wiki/GPR21" title="GPR21">21</a>, <a href="/wiki/GPR22" title="GPR22">22</a>, <a href="/wiki/LPAR4" title="LPAR4">23</a>, <a href="/wiki/GPR25" title="GPR25">25</a>, <a href="/wiki/GPR26" title="GPR26">26</a>, <a href="/wiki/GPR27" title="GPR27">27</a>, <a href="/wiki/GPR31" title="GPR31">31</a>, <a href="/wiki/GPR32" title="GPR32">32</a>, <a href="/wiki/GPR33" title="GPR33">33</a>, <a href="/wiki/GPR34" title="GPR34">34</a>, <a href="/wiki/GPR35" title="GPR35">35</a>, <a href="/wiki/GPR37" title="GPR37">37</a>, <a href="/wiki/GPR39" title="GPR39">39</a>, <a href="/wiki/GPR42" title="GPR42">42</a>, <a href="/wiki/GPR44" title="GPR44">44</a>, <a href="/wiki/GPR45" title="GPR45">45</a>, <a href="/wiki/GPR50" title="GPR50">50</a>, <a href="/wiki/GPR52" title="GPR52">52</a>, <a href="/wiki/GPR55" title="GPR55">55</a>, <a href="/wiki/GPR61" title="GPR61">61</a>, <a href="/wiki/GPR62" title="GPR62">62</a>, <a href="/wiki/GPR63" title="GPR63">63</a>, <a href="/wiki/GPR65" title="GPR65">65</a>, <a href="/wiki/GPR68" title="GPR68">68</a>, <a href="/wiki/GPR75" title="GPR75">75</a>, <a href="/wiki/GPR77" title="GPR77">77</a>, <a href="/wiki/GPR78" title="GPR78">78</a>, <a href="/wiki/GPR81" title="GPR81">81</a>, <a href="/wiki/GPR82" title="GPR82">82</a>, <a href="/wiki/GPR83" title="GPR83">83</a>, <a href="/wiki/GPR84" title="GPR84">84</a>, <a href="/wiki/GPR85" title="GPR85">85</a>, <a href="/wiki/GPR87" title="GPR87">87</a>, <a href="/wiki/GPR88" title="GPR88">88</a>, <a href="/wiki/LPAR5" title="LPAR5">92</a>, <a href="/wiki/GPR101" title="GPR101">101</a>, <a href="/wiki/GPR103" title="GPR103">103</a>, <a href="/wiki/Niacinski_receptor_1" title="Niacinski receptor 1">109A</a>, <a href="/wiki/Niacinski_receptor_2" title="Niacinski receptor 2">109B</a>, <a href="/wiki/GPR119" title="GPR119">119</a>, <a href="/wiki/GPR120" title="GPR120">120</a>, <a href="/wiki/GPR132" title="GPR132">132</a>, <a href="/wiki/GPR135" title="GPR135">135</a>, <a href="/wiki/GPR137B" title="GPR137B">137B</a>, <a href="/wiki/GPR139" title="GPR139">139</a>, <a href="/wiki/GPR141" title="GPR141">141</a>, <a href="/wiki/GPR142" title="GPR142">142</a>, <a href="/wiki/GPR146" title="GPR146">146</a>, <a href="/wiki/GPR148" title="GPR148">148</a>, <a href="/wiki/GPR149" title="GPR149">149</a>, <a href="/wiki/GPR150" title="GPR150">150</a>, <a href="/wiki/GPR151" title="GPR151">151</a>, <a href="/wiki/GPR152" title="GPR152">152</a>, <a href="/wiki/GPR153" title="GPR153">153</a>, <a href="/wiki/GPR160" title="GPR160">160</a>, <a href="/wiki/GPR161" title="GPR161">161</a>, <a href="/wiki/GPR162" title="GPR162">162</a>, <a href="/wiki/GPR171" title="GPR171">171</a>, <a href="/wiki/GPR173" title="GPR173">173</a>, <a href="/wiki/GPR174" title="GPR174">174</a>, <a href="/wiki/GPR176" title="GPR176">176</a>, <a href="/wiki/GPR177" title="GPR177">177</a>, <a href="/wiki/GPR182" title="GPR182">182</a>, <a href="/wiki/GPR183" title="GPR183">183</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;"><i>Drugi</i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"><a href="/wiki/GPR182" title="GPR182">Adrenomedulin</a>&#160;&#8226;&#32; <a href="/wiki/Mirisni_receptori" title="Mirisni receptori">Mirisni</a>&#160;&#8226;&#32; <a href="/wiki/Opsin" title="Opsin">Opsin</a> (<a href="/wiki/OPN3" title="OPN3">3</a>, <a href="/wiki/Melanopsin" title="Melanopsin">4</a>, <a href="/wiki/OPN5" title="OPN5">5</a>, <a href="/wiki/OPN1LW" title="OPN1LW">1LW</a>, <a href="/wiki/OPN1MW" title="OPN1MW">1MW</a>, <a href="/wiki/OPN1SW" title="OPN1SW">1SW</a>, <a href="/wiki/Retinalni_G_protein_spregnuti_receptor" title="Retinalni G protein spregnuti receptor">RGR</a>, <a href="/wiki/RRH" title="RRH">RRH</a>)&#160;&#8226;&#32; <a href="/wiki/Proteazom-aktivirani_receptor" title="Proteazom-aktivirani receptor">Proteazom-aktivirani</a> (<a href="/wiki/Receptor_koagulacionog_faktora_II" title="Receptor koagulacionog faktora II">1</a>, <a href="/wiki/F2RL1" title="F2RL1">2</a>, <a href="/wiki/F2RL2" title="F2RL2">3</a>, <a href="/wiki/F2RL3" title="F2RL3">4</a>)&#160;&#8226;&#32; <a href="/wiki/SREB" title="SREB">SREB</a> (<a href="/wiki/GPR27" title="GPR27">1</a>, <a href="/wiki/GPR85" title="GPR85">2</a>, <a href="/wiki/GPR173" title="GPR173">3</a>)</div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:left; background-color: AntiqueWhite"><a href="/wiki/Sekretinska_receptorska_familija" title="Sekretinska receptorska familija">Klasa B</a>: <a href="/wiki/Sekretinski_receptor" title="Sekretinski receptor">Sekretinu</a> slični</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:19.1em;"><a href="/wiki/Orfan_receptor" title="Orfan receptor">Orfan</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;;background-color: AntiqueWhite;"><div style="padding:0 0.25em"><i>GPR</i> (<a href="/wiki/GPR56" title="GPR56">56</a>, <a href="/wiki/GPR64" title="GPR64">64</a>, <a href="/wiki/GPR97" title="GPR97">97</a>, <a href="/wiki/GPR98" title="GPR98">98</a>, <a href="/wiki/GPR110" title="GPR110">110</a>, <a href="/wiki/GPR111" title="GPR111">111</a>, <a href="/wiki/GPR112" title="GPR112">112</a>, <a href="/wiki/GPR113" title="GPR113">113</a>, <a href="/wiki/GPR114" title="GPR114">114</a>, <a href="/wiki/GPR115" title="GPR115">115</a>, <a href="/wiki/GPR116" title="GPR116">116</a>, <a href="/wiki/GPR123" title="GPR123">123</a>, <a href="/wiki/GPR124" title="GPR124">124</a>, <a href="/wiki/GPR125" title="GPR125">125</a>, <a href="/wiki/GPR126" title="GPR126">126</a>, <a href="/wiki/GPR128" title="GPR128">128</a>, <a href="/wiki/GPR133" title="GPR133">133</a>, <a href="/wiki/GPR143" title="GPR143">143</a>, <a href="/wiki/GPR144" title="GPR144">144</a>, <a href="/wiki/GPR155" title="GPR155">155</a>, <a href="/wiki/GPR157" title="GPR157">157</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:19.1em;"><i>Drugi</i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"><a href="/wiki/Mo%C5%BEdano_specifi%C4%8Dni_angiogenezni_inhibitor" title="Moždano specifični angiogenezni inhibitor">Moždano specifični angiogenezni inhibitor</a> (<a href="/wiki/Mo%C5%BEdano_specifi%C4%8Dni_angiogenezni_inhibitor_1" title="Moždano specifični angiogenezni inhibitor 1">1</a>, <a href="/wiki/Mo%C5%BEdano_specifi%C4%8Dni_angiogenezni_inhibitor_2" title="Moždano specifični angiogenezni inhibitor 2">2</a>, <a href="/wiki/Mo%C5%BEdano_specifi%C4%8Dni_angiogenezni_inhibitor_3" title="Moždano specifični angiogenezni inhibitor 3">3</a>)&#160;&#8226;&#32; <a href="/wiki/Flamingo_(protein)" title="Flamingo (protein)">Kadherin</a> (<a href="/wiki/CELSR1" title="CELSR1">1</a>, <a href="/wiki/CELSR2" title="CELSR2">2</a>, <a href="/wiki/CELSR3" title="CELSR3">3</a>)&#160;&#8226;&#32; <a href="/wiki/Kalcitoninski_receptor" title="Kalcitoninski receptor">Kalcitonin</a>&#160;&#8226;&#32; <a href="/wiki/CALCRL" title="CALCRL">CALCRL</a>&#160;&#8226;&#32; <a href="/wiki/CD97" title="CD97">CD97</a>&#160;&#8226;&#32; <a href="/wiki/Kortikotropin-osloba%C4%91aju%C4%87i_hormonski_receptor" title="Kortikotropin-oslobađajući hormonski receptor">Kortikotropin-oslobađajući hormon</a> (<a href="/wiki/Kortikotropin-osloba%C4%91aju%C4%87i_hormonski_receptor_1" title="Kortikotropin-oslobađajući hormonski receptor 1">1</a>, <a href="/wiki/Kortikotropin-osloba%C4%91aju%C4%87i_hormonski_receptor_2" title="Kortikotropin-oslobađajući hormonski receptor 2">2</a>)&#160;&#8226;&#32; <a href="/wiki/EMR_receptor" title="EMR receptor">EMR</a> (<a href="/wiki/EMR1" title="EMR1">1</a>, <a href="/wiki/EMR2" title="EMR2">2</a>, <a href="/wiki/EMR3" title="EMR3">3</a>)&#160;&#8226;&#32; <a href="/wiki/Glukagonska_receptorska_familija" title="Glukagonska receptorska familija">Glukagon</a> (<a href="/wiki/Glukagonski_receptor" title="Glukagonski receptor">GR</a>, <a href="/wiki/Receptor_gastri%C4%8Dnog_inhibitornog_polipeptida" title="Receptor gastričnog inhibitornog polipeptida">GIPR</a>, <a href="/wiki/Receptor_glukagonu_sli%C4%8Dnog_peptida_1" title="Receptor glukagonu sličnog peptida 1">GLP1R</a>, <a href="/wiki/Receptor_glukagonu_sli%C4%8Dnog_peptida_2" title="Receptor glukagonu sličnog peptida 2">GLP2R</a>)&#160;&#8226;&#32; <a href="/wiki/Hormon_rasta_osloba%C4%91aju%C4%87i_hormonski_receptor" title="Hormon rasta oslobađajući hormonski receptor">Hormon rasta</a>&#160;&#8226;&#32; <a href="/wiki/ADCYAP1R1" title="ADCYAP1R1">PACAPR1</a>&#160;&#8226;&#32; <a href="/wiki/Orfan_receptor" title="Orfan receptor">GPR</a>&#160;&#8226;&#32; <a href="/wiki/Latrofilinski_receptor" title="Latrofilinski receptor">Latrofilin</a> (<a href="/wiki/LPHN1" title="LPHN1">1</a>, <a href="/wiki/LPHN2" title="LPHN2">2</a>, <a href="/wiki/LPHN3" title="LPHN3">3</a>, <a href="/wiki/ELTD1" title="ELTD1">ELTD1</a>)&#160;&#8226;&#32; <a href="/wiki/Metuzalemski_protein" title="Metuzalemski protein">Metuzalemski protein</a>&#160;&#8226;&#32; <a href="/wiki/Receptor_paratiroidnog_hormona" title="Receptor paratiroidnog hormona">Paratiroidni hormon</a> (<a href="/wiki/Receptor_paratiroidnog_hormona_1" title="Receptor paratiroidnog hormona 1">1</a>, <a href="/wiki/Receptor_paratiroidnog_hormona_2" title="Receptor paratiroidnog hormona 2">2</a>)&#160;&#8226;&#32; <a href="/wiki/Sekretinski_receptor" title="Sekretinski receptor">Sekretin</a>&#160;&#8226;&#32; <a href="/wiki/Receptor_vazoaktivnog_intestinalnog_peptida" title="Receptor vazoaktivnog intestinalnog peptida">Vazoaktivni intestinalni peptid</a> (<a href="/wiki/VIPR1" title="VIPR1">1</a>, <a href="/wiki/VIPR2" title="VIPR2">2</a>)</div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:left; background-color: AntiqueWhite"><a href="/wiki/Klasa_C_GPCR" title="Klasa C GPCR">Klasa C</a>: <a href="/wiki/Metabotropni_receptor" title="Metabotropni receptor">Metabotropni</a><br /><a href="/wiki/Metabotropni_glutamatni_receptor" title="Metabotropni glutamatni receptor">glutamat</a> / <a href="/wiki/Feromon" title="Feromon">feromon</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:19.1em;"><a href="/wiki/Receptor_ukusa" title="Receptor ukusa">Ukus</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;;background-color: AntiqueWhite;"><div style="padding:0 0.25em"><i>TAS1R</i> (<a href="/wiki/TAS1R1" title="TAS1R1">1</a>, <a href="/wiki/TAS1R2" title="TAS1R2">2</a>, <a href="/wiki/TAS1R3" title="TAS1R3">3</a>)&#160;&#8226;&#32; <i>TAS2R</i> (<a href="/wiki/TAS2R1" title="TAS2R1">1</a>, <a href="/wiki/TAS2R3" title="TAS2R3">3</a>, <a href="/wiki/TAS2R4" title="TAS2R4">4</a>, <a href="/wiki/TAS2R5" title="TAS2R5">5</a>, <a href="/wiki/TAS2R8" title="TAS2R8">8</a>, <a href="/wiki/TAS2R9" title="TAS2R9">9</a>, <a href="/wiki/TAS2R10" title="TAS2R10">10</a>, <a href="/wiki/TAS2R12" title="TAS2R12">12</a>, <a href="/wiki/TAS2R13" title="TAS2R13">13</a>, <a href="/wiki/TAS2R14" title="TAS2R14">14</a>, <a href="/wiki/TAS2R16" title="TAS2R16">16</a>, <a href="/wiki/TAS2R19" title="TAS2R19">19</a>, <a href="/wiki/TAS2R20" title="TAS2R20">20</a>, <a href="/wiki/TAS2R30" title="TAS2R30">30</a>, <a href="/wiki/TAS2R31" title="TAS2R31">31</a>, <a href="/wiki/TAS2R38" title="TAS2R38">38</a>, <a href="/wiki/TAS2R39" title="TAS2R39">39</a>, <a href="/wiki/TAS2R40" title="TAS2R40">40</a>, <a href="/wiki/TAS2R41" title="TAS2R41">41</a>, <a href="/wiki/TAS2R42" title="TAS2R42">42</a>, <a href="/wiki/TAS2R43" title="TAS2R43">43</a>, <a href="/wiki/TAS2R45" title="TAS2R45">45</a>, <a href="/wiki/TAS2R46" title="TAS2R46">46</a>, <a href="/wiki/TAS2R50" title="TAS2R50">50</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:19.1em;"><i>Drugi</i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"><a href="/wiki/Kalcijum-detektuju%C4%87i_receptor" title="Kalcijum-detektujući receptor">Kalcijum-detektujući receptor</a>&#160;&#8226;&#32; <a href="/wiki/GABAB_receptor" title="GABAB receptor">GABA B</a> (<a href="/wiki/GABBR1" title="GABBR1">1</a>, <a href="/wiki/GABBR2" title="GABBR2">2</a>)&#160;&#8226;&#32; <a href="/wiki/Glutamatni_receptor" title="Glutamatni receptor">Glutamatni receptor</a> (<a href="/wiki/Metabotropni_glutamatni_receptor" title="Metabotropni glutamatni receptor">Metabotropni glutamat</a> (<a href="/wiki/Metabotropni_glutamatni_receptor_1" title="Metabotropni glutamatni receptor 1">1</a>, <a href="/wiki/Metabotropni_glutamatni_receptor_2" title="Metabotropni glutamatni receptor 2">2</a>, <a href="/wiki/Metabotropni_glutamatni_receptor_3" title="Metabotropni glutamatni receptor 3">3</a>, <a href="/wiki/Metabotropni_glutamatni_receptor_4" title="Metabotropni glutamatni receptor 4">4</a>, <a href="/wiki/Metabotropni_glutamatni_receptor_5" title="Metabotropni glutamatni receptor 5">5</a>, <a href="/wiki/Metabotropni_glutamatni_receptor_6" title="Metabotropni glutamatni receptor 6">6</a>, <a href="/wiki/Metabotropni_glutamatni_receptor_7" title="Metabotropni glutamatni receptor 7">7</a>, <a href="/wiki/Metabotropni_glutamatni_receptor_8" title="Metabotropni glutamatni receptor 8">8</a>))&#160;&#8226;&#32; <a href="/wiki/GPRC6A" title="GPRC6A">GPRC6A</a>&#160;&#8226;&#32; <a href="/wiki/Orfan_receptor" title="Orfan receptor">GPR</a> (<a href="/wiki/GPR156" title="GPR156">156</a>, <a href="/wiki/GPR158" title="GPR158">158</a>, <a href="/wiki/GPR179" title="GPR179">179</a>)&#160;&#8226;&#32; <a href="/wiki/RAIG" title="RAIG">RAIG</a> (<a href="/wiki/GPRC5A" title="GPRC5A">1</a>, <a href="/wiki/GPRC5B" title="GPRC5B">2</a>, <a href="/wiki/GPRC5C" title="GPRC5C">3</a>, <a href="/wiki/GPRC5D" title="GPRC5D">4</a>)&#160;&#8226;&#32; <a href="/wiki/Vomeronazalni_receptor" title="Vomeronazalni receptor">VNR</a> (<a href="/wiki/VN1R1" title="VN1R1">1</a>, <a href="/wiki/VN1R2" title="VN1R2">2</a>, <a href="/wiki/VN1R3" title="VN1R3">3</a>, <a href="/wiki/VN1R5" title="VN1R5">5</a>)</div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:left; background-color: AntiqueWhite">Klasa F:<br /><a href="/wiki/Uvojiti_receptori" title="Uvojiti receptori">Frizzled</a> / <a href="/wiki/Zagla%C4%91eni_receptori" title="Zaglađeni receptori">Zaglađeni</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:19.1em;">Uvojiti</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;;background-color: AntiqueWhite;"><div style="padding:0 0.25em"><a href="/wiki/Uvojiti_receptori" title="Uvojiti receptori">Frizzled</a> (<a href="/wiki/FZD1" title="FZD1">1</a>, <a href="/wiki/FZD2" title="FZD2">2</a>, <a href="/wiki/FZD3" title="FZD3">3</a>, <a href="/wiki/FZD4" title="FZD4">4</a>, <a href="/wiki/FZD5" title="FZD5">5</a>, <a href="/wiki/FZD6" title="FZD6">6</a>, <a href="/wiki/FZD7" title="FZD7">7</a>, <a href="/wiki/FZD8" title="FZD8">8</a>, <a href="/wiki/FZD9" title="FZD9">9</a>, <a href="/wiki/FZD10" title="FZD10">10</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:19.1em;">Zaglađeni</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"><a href="/wiki/Zagla%C4%91eni_receptori" title="Zaglađeni receptori">Zaglađeni</a></div></td></tr></tbody></table><div></div></td></tr></tbody></table></div> <!-- NewPP limit report Parsed by mw‐api‐int.codfw.main‐648bd44df8‐9w5fn Cached time: 20241117013515 Cache expiry: 2592000 Reduced expiry: false Complications: [show‐toc] CPU time usage: 0.826 seconds Real time usage: 0.945 seconds Preprocessor visited node count: 2911/1000000 Post‐expand include size: 306872/2097152 bytes Template argument size: 31532/2097152 bytes Highest expansion depth: 12/100 Expensive parser function count: 0/500 Unstrip recursion depth: 0/20 Unstrip post‐expand size: 39075/5000000 bytes Lua time 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