CINXE.COM
Next-generation sequencing partnership announced between ANGLE plc and NuProbe
<!DOCTYPE html><html lang="en"><head><link rel="stylesheet" data-href="https://fonts.googleapis.com/css?family=Trade+Gothic+Lt+Bold%7COpen+Sans%7CTrade+Gothic+Lt&display=swap" data-optimized-fonts="true"/><title>Next-generation sequencing partnership announced between ANGLE plc and NuProbe</title><link rel="icon" href="https://cdn.magloft.com/pwa-664/pwa/logo/8eb186e1-b2cb-4384-a0b7-515f62171b22.png"/><link rel="shortcut icon" type="image/x-icon" href="https://cdn.magloft.com/pwa-664/pwa/logo/8eb186e1-b2cb-4384-a0b7-515f62171b22.png?optimizer=image&format=webp&width=180&aspectRatio=1"/><link rel="apple-touch-icon" sizes="180x180" href="https://cdn.magloft.com/pwa-664/pwa/logo/8eb186e1-b2cb-4384-a0b7-515f62171b22.png?optimizer=image&format=webp&width=180&aspectRatio=1"/><link rel="canonical" href="/domains/www.pharmafocus.com/articles/next-generation-sequencing-partnership-announced-between-angle-p"/><meta name="application-name" content="Next-generation sequencing partnership announced between ANGLE plc and NuProbe"/><meta name="apple-mobile-web-app-capable" content="yes"/><meta name="apple-mobile-web-app-status-bar-style" content="default"/><meta name="apple-mobile-web-app-title" content="Next-generation sequencing partnership announced between ANGLE plc and NuProbe"/><meta name="format-detection" content="telephone=no"/><meta name="mobile-web-app-capable" content="yes"/><meta name="msapplication-TileColor" content="#1976D2"/><meta name="msapplication-tap-highlight" content="no"/><link rel="manifest" href="/manifest.json"/><meta name="twitter:url" content="https://www.pharmafocus.com"/><meta name="theme-color" content="#1976D2"/><meta name="viewport" content="width=device-width, initial-scale=1"/><meta charSet="utf-8"/><meta itemProp="name" content="Next-generation sequencing partnership announced between ANGLE plc and NuProbe"/><meta name="keywords" content="partnership"/><meta itemProp="description" content="Liquid biopsy company ANGLE plc has announced a partnership with NuProbe, a genomics and molecular diagnostics company"/><meta name="description" content="Liquid biopsy company ANGLE plc has announced a partnership with NuProbe, a genomics and molecular diagnostics company"/><meta itemProp="image" content="https://cdn.magloft.com/pdf-import/1125/images/img_10-2.jpg"/><meta property="og:description" content="Liquid biopsy company ANGLE plc has announced a partnership with NuProbe, a genomics and molecular diagnostics company"/><meta property="og:title" content="Next-generation sequencing partnership announced between ANGLE plc and NuProbe"/><meta property="og:site_name" content="Next-generation sequencing partnership announced between ANGLE plc and NuProbe"/><meta property="og:image" content="https://cdn.magloft.com/pdf-import/1125/images/img_10-2.jpg"/><meta property="og:type" content="website"/><meta name="twitter:card" content="summary_large_image"/><meta name="twitter:title" content="Next-generation sequencing partnership announced between ANGLE plc and NuProbe"/><meta name="twitter:description" content="Liquid biopsy company ANGLE plc has announced a partnership with NuProbe, a genomics and molecular diagnostics company"/><meta name="twitter:image" content="https://cdn.magloft.com/pdf-import/1125/images/img_10-2.jpg"/><meta name="author" content="Pharmafocus"/><meta property="article:author" content="Pharmafocus"/><meta property="article:published_time" content="2024-10-10T00:00:00.000Z"/><meta name="twitter:site" content="@Pharmafocus"/><meta name="twitter:creator" content="@Pharmafocus"/><style>html{--heading-font: "Trade Gothic Lt Bold";--body-font: "Open Sans";--ui-font: "Trade Gothic Lt Bold";--top-menu-title-font: "Trade Gothic Lt Bold";--top-menu-subtitle-font: "Trade Gothic Lt";--top-menu-items-font: "Trade Gothic Lt";--footer-menu-title-font: "Trade Gothic Lt Bold";--footer-menu-items-font: "Trade Gothic Lt Bold";--background-color: #FFFFFF;--background-color-dark: #808080;--primary-color: #1976D2;--primary-color-dark: #0C3B69;--secondary-color: #795FF4;--secondary-color-dark: #250B9F;--accent-color: #D76FD6;--accent-color-dark: #80237F;--info-color: #41638C;--info-color-dark: #213246;--warning-color: #EF9338;--warning-color-dark: #89490B;--success-color: #20AD27;--success-color-dark: #105714;--danger-color: #DF4241;--danger-color-dark: #7B1515;--top-menu-background-color: #EE1C25;--top-menu-background-color-dark: #7C090E;--footer-menu-background-color: #DF1111;--footer-menu-background-color-dark: #6F0808;--navbar-height: 64px; }</style><link rel="stylesheet" href="https://cdn.magloft.com/reader/fonts/trade-gothic-lt.css"/><link rel="stylesheet" href="https://cdn.magloft.com/reader/fonts/trade-gothic-lt-bold.css"/><script type="text/javascript" src="https://cdn.jsdelivr.net/npm/cookie-bar/cookiebar-latest.min.js?customize=1&always=1&showNoConsent=1"></script><meta name="google-site-verification" content="kuOvGxaH_NjG3aS7GSmbjjV-OjdOAWyiM3gEPGESeHQ"/><style> #billboard-banner { text-align:center;} #billboard-banner img {width:100%; max-width:970px; height:auto; position:relative; top:70px;} .Layout_spacer__qTBD3 {margin-top:70px;} </style><meta name="next-head-count" content="44"/><link rel="preconnect" href="https://fonts.googleapis.com"/><link rel="preconnect" href="https://fonts.gstatic.com"/><link rel="preload" href="/_next/static/css/229efe2956472d85.css" as="style"/><link rel="stylesheet" href="/_next/static/css/229efe2956472d85.css" data-n-g=""/><link rel="preload" href="/_next/static/css/7c74bf24f71f6c9d.css" as="style"/><link rel="stylesheet" href="/_next/static/css/7c74bf24f71f6c9d.css" data-n-p=""/><link rel="preload" href="/_next/static/css/eaa0062c2481f7ca.css" as="style"/><link rel="stylesheet" href="/_next/static/css/eaa0062c2481f7ca.css" data-n-p=""/><noscript data-n-css=""></noscript><script defer="" nomodule="" src="/_next/static/chunks/polyfills-c67a75d1b6f99dc8.js"></script><script defer="" src="https://fonts.googleapis.com/css?family=Open+Sans&display=swap" data-nscript="beforeInteractive"></script><script src="/_next/static/chunks/webpack-b653c683a51d8b57.js" defer=""></script><script src="/_next/static/chunks/framework-73b8966a3c579ab0.js" defer=""></script><script src="/_next/static/chunks/main-34cb81d5753e1fc4.js" defer=""></script><script src="/_next/static/chunks/pages/_app-9cc101b503fd5646.js" defer=""></script><script src="/_next/static/chunks/ad273671-3092333ffa02af02.js" defer=""></script><script src="/_next/static/chunks/876-c944523f292a2885.js" defer=""></script><script src="/_next/static/chunks/223-fe6833f316a5a95f.js" defer=""></script><script src="/_next/static/chunks/174-d95909d2aa5e8ec8.js" defer=""></script><script src="/_next/static/chunks/302-d0f1826200f9f2a4.js" defer=""></script><script src="/_next/static/chunks/pages/domains/%5Bdomain%5D/articles/%5Bslug%5D-12d0888066c7f18b.js" defer=""></script><script src="/_next/static/1bBCYhXOG7wsYuaBifvjK/_buildManifest.js" defer=""></script><script src="/_next/static/1bBCYhXOG7wsYuaBifvjK/_ssgManifest.js" defer=""></script><style data-styled="" data-styled-version="5.3.9"></style><link rel="stylesheet" href="https://fonts.googleapis.com/css?family=Trade+Gothic+Lt+Bold%7COpen+Sans%7CTrade+Gothic+Lt&display=swap"/></head><body><div id="__next"><div class="Layout_container__gktH6"><div class="Layout_navbar-container__gCfDZ" style="height:64px"><nav class="_wrapper_jbnbd_1"><div class="_container_jbnbd_15"><div class="_navbar-prefix_jbnbd_108"><div class="Layout_prefix__7W2Vq"><button><div class="_nav-arrow-left_1lm7t_183 _icon_1lm7t_1 icon"></div></button></div></div><a class="_navbar-brand_jbnbd_29" aria-label="Pharmafocus" href="/"><div class="_navbar-image_jbnbd_40"><img alt="Logo" loading="lazy" decoding="async" data-nimg="fill" class="_image_jbnbd_43" style="position:absolute;height:100%;width:100%;left:0;top:0;right:0;bottom:0;color:transparent" sizes="100vw" srcSet="https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 54w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 70w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 82w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 96w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 110w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 128w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 138w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 192w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 200w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 252w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 260w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 298w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 378w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 384w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 520w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 640w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 756w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 828w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 1080w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 1200w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 1920w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 2048w" src="https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png"/></div><div class="_navbar-title_jbnbd_58 _navbar-title-hide_jbnbd_101"></div></a><div id="navbar-children-container" class="_navbar-children_jbnbd_116"><div class="_menu_1jhrl_1"><div class="_menu-wrapper_1jhrl_22"><div class="_menu-items_1jhrl_38"><a class="_menu-item_1jhrl_38" href="/"><div class="_menu-home_1lm7t_255 _menu-item-icon_1jhrl_97 _icon_1lm7t_1 icon"></div><div class="_menu-item-title_1jhrl_88">Home</div><div class="_indicator_1jhrl_63"></div></a><a class="_menu-item_1jhrl_38 _active_1jhrl_70" href="/articles"><div class="_menu-articles_1lm7t_259 _menu-item-icon_1jhrl_97 _icon_1lm7t_1 icon"></div><div class="_menu-item-title_1jhrl_88">Articles</div><div class="_indicator_1jhrl_63 _active_1jhrl_70"></div></a><a class="_menu-item_1jhrl_38" href="/collections"><div class="_menu-issues_1lm7t_263 _menu-item-icon_1jhrl_97 _icon_1lm7t_1 icon"></div><div class="_menu-item-title_1jhrl_88">Magazines</div><div class="_indicator_1jhrl_63"></div></a><a class="_menu-item_1jhrl_38" href="/account/login"><div class="_menu-account_1lm7t_411 _menu-item-icon_1jhrl_97 _icon_1lm7t_1 icon"></div><div class="_menu-item-title_1jhrl_88">Log in</div><div class="_indicator_1jhrl_63"></div></a></div></div></div></div><div id="navbar-suffix" class="_navbar-suffix_jbnbd_108"><div class="Layout_menu-actions__vsDbI"><div class="Layout_install-button__FBfSr"><div class="Tooltip_tooltip__98Sw9"></div><button class="_button_19h3g_1 _text_19h3g_12 _medium_19h3g_38 _secondary_19h3g_22" type="button" style="color:var(--top-menu-item-icon-color, var(--background-color))" role="button" aria-label="Search" aria-labelledby="labeldiv" title="Search"><div class="_action-search_1lm7t_15 _icon-button_19h3g_19 _icon_1lm7t_1 icon" style="background-color:var(--top-menu-item-icon-color, var(--background-color))"></div></button></div></div></div></div></nav></div><div class="Layout_main__evUHx"><div class="Layout_spacer__qTBD3" style="height:64px"></div><div class=""><div class=""></div><div class=""><div id="print-article" class="_slug__article__BPEHu"><div class="Article-module_article__kO4b9"><div id="outer" data-widget="page-widget" style="background-color:#FFFFFF;padding:16px 0px 24px 0px;color:#000000;text-align:left;font-family:"Open Sans"" class="Widget-module_outer__PBh8P Page-module_outer__g0XXH"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%"><div id="outer" data-widget="paragraph-widget" style="background-color:transparent;padding:0px 24px 0px 24px;text-align:left;font-size:100%;line-height:1.3;letter-spacing:0" class="Widget-module_outer__PBh8P Paragraph-module_container__-DJUN"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%;column-count:1"><p>Research & Development</p></div></div><div id="outer" data-widget="horizontal-rule-widget" style="background-color:transparent;padding:0px 24px 0px 24px" class="Widget-module_outer__PBh8P HorizontalRule-module_outer__3UqSE"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%"><hr style="border-top-style:solid;border-top-width:3px;border-top-color:#a31f29"/></div></div><div id="outer" data-widget="heading-widget" style="background-color:transparent;padding:0px 24px 16px 24px;text-align:left;font-size:100%;line-height:1.3;letter-spacing:0" class="Widget-module_outer__PBh8P Heading-module_container__uHf-4"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%"><h2><span style="font-family:"Roboto Slab"" class="__bold">Next-generation sequencing partnership announced between ANGLE plc and NuProbe</span></h2></div></div><div id="outer" data-widget="paragraph-widget" style="background-color:transparent;padding:0px 24px 8px 24px;text-align:left;font-size:100%;line-height:1.3;letter-spacing:0" class="Widget-module_outer__PBh8P Paragraph-module_container__-DJUN"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%;column-count:1"><p><span class="__bold" style="color:rgb(28,28,28)">Liquid biopsy company ANGLE plc has announced a partnership with NuProbe, a genomics and molecular diagnostics company, to utilise the latter’s pan-cancer next-generation sequencing (NGS) panel. </span></p></div></div><div id="outer" data-widget="image-widget" style="background-color:transparent;padding:8px 24px 16px 24px;min-height:auto" class="Widget-module_outer__PBh8P"><div id="inner" class="Image-module_container__8raIv Image-module_container-noflex__-J1PG" style="border-radius:0px 0px 0px 0px;width:100%;min-height:auto"><picture class="Image-module_picture__gw1zY Image-module_loading__FfyPr"><source type="image/jpeg" srcSet="https://cdn.magloft.com/pdf-import/1125/images/img_10-2.jpg?optimizer=image&width=192 192w,https://cdn.magloft.com/pdf-import/1125/images/img_10-2.jpg?optimizer=image&width=384 384w,https://cdn.magloft.com/pdf-import/1125/images/img_10-2.jpg?optimizer=image&width=768 768w,https://cdn.magloft.com/pdf-import/1125/images/img_10-2.jpg?optimizer=image&width=1536 1536w" sizes="(min-width: 768px) 768px, 100vw"/><img src="https://cdn.magloft.com/pdf-import/1125/images/img_10-2.jpg?optimizer=image&width=768" srcSet="https://cdn.magloft.com/pdf-import/1125/images/img_10-2.jpg?optimizer=image&width=192 192w,https://cdn.magloft.com/pdf-import/1125/images/img_10-2.jpg?optimizer=image&width=384 384w,https://cdn.magloft.com/pdf-import/1125/images/img_10-2.jpg?optimizer=image&width=768 768w,https://cdn.magloft.com/pdf-import/1125/images/img_10-2.jpg?optimizer=image&width=1536 1536w" sizes="(min-width: 768px) 768px, 100vw" class="Image-module_image__w4slc" width="100%" height="1040" decoding="async" alt="Image" style="height:auto;width:100%"/></picture></div></div><div id="outer" data-widget="paragraph-widget" style="background-color:transparent;padding:0px 24px 8px 24px;text-align:left;font-size:100%;line-height:1.3;letter-spacing:0" class="Widget-module_outer__PBh8P Paragraph-module_container__-DJUN"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%;column-count:1"><p>Under the terms of the agreement, ANGLE has been granted an option for an exclusive global licence to the NGS panel outside of China, for the analysis of circulating tumour cells (CTC) and the dual analysis of CTCs and circulating tumour DNA (ctDNA). This NGS panel enables highly sensitive and specific detection of over 6,500 DNA mutations in 61 clinically relevant genes.</p></div></div><div id="outer" data-widget="paragraph-widget" style="background-color:transparent;padding:0px 24px 8px 24px;text-align:left;font-size:100%;line-height:1.3;letter-spacing:0" class="Widget-module_outer__PBh8P Paragraph-module_container__-DJUN"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%;column-count:1"><p>For the first stage of the collaboration, NuProbe will transfer manufacture of the NGS panel to a large-scale manufacturing site, and ANGLE will undertake internal validation of the initial batches.</p></div></div><div id="outer" data-widget="paragraph-widget" style="background-color:transparent;padding:0px 24px 8px 24px;text-align:left;font-size:100%;line-height:1.3;letter-spacing:0" class="Widget-module_outer__PBh8P Paragraph-module_container__-DJUN"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%;column-count:1"><p>Repeatable, minimally invasive molecular profiling using liquid biopsy analytes has the potential to be used in the future by clinicians for tracking tumour evolution, treatment response, early identification of drug resistance and disease progression.</p></div></div><div id="outer" data-widget="paragraph-widget" style="background-color:transparent;padding:0px 24px 8px 24px;text-align:left;font-size:100%;line-height:1.3;letter-spacing:0" class="Widget-module_outer__PBh8P Paragraph-module_container__-DJUN"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%;column-count:1"><p>NuProbe chief executive officer Yingshuang Chai, commented: “We are excited to enter into an agreement with ANGLE plc, a world leader in the harvest of CTCs from blood for analysis. NuProbe’s NGS panel is a low-cost, ultrasensitive pan-cancer NGS panel that can accurately detect mutations and has demonstrated robust performance in both CTC and ctDNA sample types. By combining CTC and ctDNA detection, this collaboration will help drive the development of personalised treatment options for cancer patients. We look forward to the development of a strong partnership with ANGLE in the future.”</p></div></div><div id="outer" data-widget="paragraph-widget" style="background-color:transparent;padding:0px 24px 8px 24px;text-align:left;font-size:100%;line-height:1.3;letter-spacing:0" class="Widget-module_outer__PBh8P Paragraph-module_container__-DJUN"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%;column-count:1"><p>ANGLE chief executive officer Andrew Newland, commented: “We are delighted to have signed an agreement with NuProbe, which grants the company an exclusive worldwide licence option (outside of China) to the NGS panel for the analysis of CTCs and dual analysis of CTCs and ctDNA. The company believes that this agreement will enable us to combine the leading CTC harvesting solution with an optimised DNA sequencing panel for analysis of CTCs and dual analysis of CTCs and ctDNA.”</p></div></div><div id="outer" data-widget="paragraph-widget" style="background-color:transparent;padding:0px 24px 8px 24px;text-align:left;font-size:100%;line-height:1.3;letter-spacing:0" class="Widget-module_outer__PBh8P Paragraph-module_container__-DJUN"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%;column-count:1"><p>ANGLE plc and NuProbe are biotech companies based in the UK and the US, respectively.</p></div></div></div></div></div><div class="_slug__share-button__ettip"><hr/></div></div></div><div id="ControlBar" class="_slug__control-bar__Jj4LE"><div class="WrapAutoHide-module_navigation__9sdQy WrapAutoHide-module_visible__UN7GD"><div class="ControlBar-module_toc-wrapper__AF5eD"><div class="ControlBar-module_toc__mKXnp"><div class="ControlBar-module_white-blur__TGapK"><div class="ControlBar-module_toc-slider__i9fv1"></div></div><div class="ControlBar-module_control-bar__9Zqak"><button class=""><svg xmlns="http://www.w3.org/2000/svg" width="24" height="24" viewBox="0 0 24 24" fill="none"><path d="M13.8287 19C13.5367 19 13.2467 18.873 13.0487 18.627L8.22066 12.627C7.92266 12.256 7.92666 11.726 8.23166 11.36L13.2317 5.35998C13.5847 4.93598 14.2157 4.87898 14.6407 5.23198C15.0647 5.58498 15.1217 6.21598 14.7677 6.63998L10.2927 12.011L14.6077 17.373C14.9537 17.803 14.8857 18.433 14.4547 18.779C14.2707 18.928 14.0487 19 13.8287 19Z" fill="white"></path></svg></button><button class=""><svg xmlns="http://www.w3.org/2000/svg" width="18" height="14" viewBox="0 0 18 14" fill="none"><path d="M6.75 0H1.125C0.503719 0 0 0.503719 0 1.125V4.5C0 5.12128 0.503719 5.625 1.125 5.625C1.74628 5.625 2.25 5.12128 2.25 4.5V2.25H6.75C7.37128 2.25 7.875 1.74628 7.875 1.125C7.875 0.503719 7.37128 0 6.75 0Z" fill="white"></path><path d="M16.875 0H11.25C10.6287 0 10.125 0.503719 10.125 1.125C10.125 1.74628 10.6287 2.25 11.25 2.25H15.75V4.5C15.75 5.12128 16.2537 5.625 16.875 5.625C17.4963 5.625 18 5.12128 18 4.5V1.125C18 0.503719 17.4963 0 16.875 0Z" fill="white"></path><path d="M16.875 7.875C16.2537 7.875 15.75 8.37872 15.75 9V11.25H11.25C10.6287 11.25 10.125 11.7537 10.125 12.375C10.125 12.9963 10.6287 13.5 11.25 13.5H16.875C17.4963 13.5 18 12.9963 18 12.375V9C18 8.37872 17.4963 7.875 16.875 7.875Z" fill="white"></path><path d="M6.75 11.25H2.25V9C2.25 8.37872 1.74628 7.875 1.125 7.875C0.503719 7.875 0 8.37872 0 9V12.375C0 12.9963 0.503719 13.5 1.125 13.5H6.75C7.37128 13.5 7.875 12.9963 7.875 12.375C7.875 11.7537 7.37128 11.25 6.75 11.25Z" fill="white"></path></svg></button><button class="" disabled=""><svg xmlns="http://www.w3.org/2000/svg" width="24" height="24" viewBox="0 0 24 24" fill="none"><g opacity="0.25"><path d="M9.9995 19C9.7735 19 9.5465 18.924 9.3595 18.768C8.9355 18.415 8.8785 17.784 9.2315 17.36L13.7075 11.989L9.3925 6.62701C9.0465 6.19701 9.1145 5.56701 9.5445 5.22101C9.9755 4.87501 10.6045 4.94301 10.9515 5.37301L15.7795 11.373C16.0775 11.744 16.0735 12.274 15.7685 12.64L10.7685 18.64C10.5705 18.877 10.2865 19 9.9995 19Z" fill="white"></path></g></svg></button></div></div></div></div></div><div class="_slug__wrapper__0ZIJf"></div><div></div></div></div><script> //create a new element const terms = document.createElement('div'); //set id terms.setAttribute("id","billboard-banner"); //add the new element to html var body = document.querySelector('body'); body.appendChild(terms); document.querySelector("#billboard-banner").innerHTML = "<ins data-revive-zoneid='1573' data-revive-id='9c421b7e485bf2edfee09708a4d06e2e'></ins>"; //insert new element before header //document.body.insertAdjacentElement('afterbegin', terms); const insElement = document.querySelector("#__next"); insElement.before(terms); </script> <script async="" src="//ads.datateam.co.uk/www/delivery/asyncjs.php"></script><div class="_footer_j8nu5_1"><div class="_container_j8nu5_12"><div class="_footer-row_j8nu5_23"><div class="_footer-column_j8nu5_36 _flex-2_j8nu5_117"><div class="_footer-brand_j8nu5_43"><div class=""><img alt="Logo" loading="lazy" width="40" height="40" decoding="async" data-nimg="1" class="_footer-logo_j8nu5_57" style="color:transparent" srcSet="https://media.magloft.app/pwa-664/pwa/logo/8eb186e1-b2cb-4384-a0b7-515f62171b22.png 1x, https://media.magloft.app/pwa-664/pwa/logo/8eb186e1-b2cb-4384-a0b7-515f62171b22.png 2x" src="https://media.magloft.app/pwa-664/pwa/logo/8eb186e1-b2cb-4384-a0b7-515f62171b22.png"/></div><div class="_content_j8nu5_67"><h3>Pharmafocus</h3><p>Pharmaceutical Industry news, analysis and insights</p></div></div><div class="_footer-link-list_j8nu5_121"><div class="_block_j8nu5_129"><a class="_footer-link-item_j8nu5_92" rel="noreferrer" href="mailto:info@pharmafile.com"><div class="_form-email_1lm7t_143 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><span>info@pharmafile.com</span></a></div><div class="_block_j8nu5_129"><a class="_footer-link-item_j8nu5_92" target="_blank" rel="noreferrer" href="http://www.pharmafile.com"><div class="_status-info_1lm7t_87 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><span>Pharmafile.com</span></a><a class="_footer-link-item_j8nu5_92" target="_blank" rel="noreferrer" href="https://magazine.pharmafile.com"><div class="_status-info_1lm7t_87 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><span>Pharmafile Magazine</span></a><a class="_footer-link-item_j8nu5_92" target="_blank" rel="noreferrer" href="http://www.samedanltd.com"><div class="_status-info_1lm7t_87 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><span>Samedan</span></a></div><a target="_blank" rel="noreferrer" class="_footer-link-item_j8nu5_92" href="https://www.pharmafile.com/privacy-policy"><div class="_status-info_1lm7t_87 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><span>Privacy Policy</span></a><a target="_blank" rel="noreferrer" class="_footer-link-item_j8nu5_92" href="https://www.pharmafile.com/terms-of-service"><div class="_status-info_1lm7t_87 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><span>Terms of Service</span></a></div></div><div class="_footer-column_j8nu5_36 _flex-1_j8nu5_39"><div class="_footer-brand_j8nu5_43"><div class="_status-accent_1lm7t_91 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><div class="_content_j8nu5_67"><h3>Categories</h3><p>Explore our inspiring content by topic</p></div></div><div class="_footer-link-list_j8nu5_121"><a class="_footer-link-item_j8nu5_92" href="/categories/uk-pharma-news"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>UK News</a><a class="_footer-link-item_j8nu5_92" href="/categories/general-news"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>General News</a><a class="_footer-link-item_j8nu5_92" href="/categories/approvals"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>Approvals</a><a class="_footer-link-item_j8nu5_92" href="/categories/research-and-development"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>R & D</a><a class="_footer-link-item_j8nu5_92" href="/categories/mergers-acquisitions"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>Mergers & Acquisitions</a><a class="_footer-link-item_j8nu5_92" href="/categories/manufacturing-production"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>Manufacturing</a><a class="_footer-link-item_j8nu5_92" href="/categories/clinical-trials"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>Clinical Trials</a><a class="_footer-link-item_j8nu5_92" href="/categories/industry-insights"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>Industry Insights</a><a class="_footer-link-item_j8nu5_92" href="/categories/appointments"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>Appointments</a><a class="_footer-link-item_j8nu5_92" href="/categories/insider-interviews"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>Interviews</a></div></div><div class="_footer-column_j8nu5_36 _flex-1_j8nu5_39"><div class="_footer-brand_j8nu5_43"><div class="_share-action_1lm7t_463 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><div class="_content_j8nu5_67"><h3>Social Footprints</h3><p>Follow us on our Social Media Channels</p></div></div><div class="_footer-link-list_j8nu5_121"><a class="_footer-link-item_j8nu5_92" target="_blank" rel="noreferrer" href="https://twitter.com/Pharmafocus"><div class="_share-twitter_1lm7t_487 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><span class="_footer-text_j8nu5_125">X</span></a><a class="_footer-link-item_j8nu5_92" target="_blank" rel="noreferrer" href="https://www.linkedin.com/company/pharmafile"><div class="_share-linkedin_1lm7t_483 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><span class="_footer-text_j8nu5_125">linkedin</span></a></div></div></div></div></div></div><div class="Toastify"></div></div><script id="__NEXT_DATA__" type="application/json">{"props":{"pageProps":{"domain":"www.pharmafocus.com","pwa":{"id":664,"publicationId":14882,"pwaOptinId":656,"domain":"www.pharmafocus.com","config":{"access":{"concurrentLimit":null,"restrictAnonymous":null,"disableSignup":null,"disableLogin":null,"disableLoginMessage":null,"disableSearchIndexing":false,"signupUrl":null,"resetPasswordUrl":null,"isUsernameLogin":null,"disableEditProfile":null,"formUrl":null,"customMarginResetPassword":null},"push":{"google":{"serverPublicKey":"BGfKWie38SRvrZs4-bDa1N70rhULMBqX8nAvBZT_2OXsMQi3uRA0CaK4JKPuib9Ega28liCTGhBx0QCY4t1QU7o"}},"tracking":{"facebook":{"appId":null,"pixelId":null},"google":{"measurementId":"G-D8QLP3CKWG"},"gtm":null,"sentry":true},"payment":{"stripe":null,"bypassPayment":null,"mode":"none","external":null,"currency":null},"email":{"readerOptin":false},"firebase":{"projectId":"ipt-magloft","senderId":"497261264876","pairKey":null,"webAppConfig":{"apiKey":"AIzaSyBcHBC8k394YdXp19dZj2Xqe8CXCgThBZs","appId":"1:497261264876:web:98452398b320341bd68ac9","authDomain":"ipt-magloft.firebaseapp.com","databaseURL":null,"locationId":null,"messagingSenderId":"497261264876","projectId":"ipt-magloft","storageBucket":"ipt-magloft.appspot.com"}},"customHtml":{"head":"\u003cscript type=\"text/javascript\" src=\"https://cdn.jsdelivr.net/npm/cookie-bar/cookiebar-latest.min.js?customize=1\u0026always=1\u0026showNoConsent=1\" onload=\"setupCookieBar();\"\u003e\u003c/script\u003e\n\u003cmeta name=\"google-site-verification\" content=\"kuOvGxaH_NjG3aS7GSmbjjV-OjdOAWyiM3gEPGESeHQ\" /\u003e\n\u003cstyle\u003e\n#billboard-banner { text-align:center;}\n#billboard-banner img {width:100%; max-width:970px; height:auto; position:relative; top:70px;}\n.Layout_spacer__qTBD3 {margin-top:70px;}\n\u003c/style\u003e","body":"\u003cscript\u003e\n //create a new element\n const terms = document.createElement('div');\n //set id\n terms.setAttribute(\"id\",\"billboard-banner\");\n //add the new element to html\n var body = document.querySelector('body');\n body.appendChild(terms);\n document.querySelector(\"#billboard-banner\").innerHTML = \"\u003cins data-revive-zoneid='1573' data-revive-id='9c421b7e485bf2edfee09708a4d06e2e'\u003e\u003c/ins\u003e\"; \n //insert new element before header\n//document.body.insertAdjacentElement('afterbegin', terms);\n const insElement = document.querySelector(\"#__next\");\n insElement.before(terms);\n\u003c/script\u003e\n\u003cscript async src=\"//ads.datateam.co.uk/www/delivery/asyncjs.php\"\u003e\u003c/script\u003e"},"account":{"emailEditable":true,"customSubscriptionText":null,"customSubscriptionURL":null,"enableSubscriptionTitle":null},"checkout":null},"design":{"colors":{"backgroundColor":"#FFFFFF","primaryColor":"#1976D2","secondaryColor":"#795FF4","accentColor":"#D76FD6","infoColor":"#41638C","warningColor":"#EF9338","successColor":"#20AD27","dangerColor":"#DF4241","topMenuBackgroundColor":"#EE1C25","topMenuHeadingTitleColor":null,"topMenuHeadingIconColor":null,"topMenuItemTextColor":null,"topMenuItemIconColor":null,"footerMenuBackgroundColor":"#DF1111","footerMenuHeadingTitleColor":null,"footerMenuHeadingTextColor":null,"footerMenuHeadingIconColor":null,"footerMenuItemTextColor":null,"footerMenuItemIconColor":null},"images":{"icon":"https://cdn.magloft.com/pwa-664/pwa/logo/8eb186e1-b2cb-4384-a0b7-515f62171b22.png","feature":"https://cdn.magloft.com/defaults/feature-graphic.jpg","topMenuIcon":"https://cdn.magloft.com/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png","footerMenuIcon":null,"alphaChannelIcon":null},"fonts":{"heading":"trade-gothic-lt-bold","body":"open-sans","ui":"trade-gothic-lt-bold","topMenuTitle":"trade-gothic-lt-bold","topMenuItems":"trade-gothic-lt","topMenuSubtitle":"trade-gothic-lt","footerMenuTitle":null,"footerMenuItems":null},"menuItems":{"collections":{"title":"Magazines"},"articles":{"title":null},"account":{"title":null},"icons":{"enabled":true}},"footerShape":"flat","issueCoverAspectRatio":0.75,"fullscreenCollectionView":"auto","customOverlayToggleView":false,"defaultViewMode":"html","categories":"flat","purchaseList":true,"libraryList":false,"noteList":false,"textToSpeech":false},"layout":{"banners":[{"image":"https://cdn.magloft.com/pwa-1/pwa/banner/aea74608-e04a-4649-b817-c45cc439e28e.png","title":"Start trial now","isHidden":true,"action":{"type":"url","href":"https://www.magloft.com/","target":"_blank","pwaSubscriptionId":null,"pwaSubscription":null,"optinId":null,"optin":null}}],"bottomBanners":[{"image":"https://cdn.magloft.com/pwa-664/pwa/banner/1f66e6ea-9b3a-4477-aba1-18abf54619b8.png","title":null,"isHidden":true,"action":{"type":"url","href":"http://www.samedanltd.com/","target":"_blank","pwaSubscriptionId":null,"pwaSubscription":null,"optinId":null,"optin":null}}],"columnSeparator":"shadow","tabs":[{"route":"","title":"Home","icon":"menu-home","visible":true},{"route":"/articles","title":"Articles","icon":"menu-articles","visible":true},{"route":"/collections","title":"Collections","icon":"menu-issues","visible":true},{"route":"/account","title":"Account","icon":"menu-account","visible":true}],"topMenu":{"showLogo":true,"showSubtitle":false,"showTitle":false,"height":"64px"},"navbar":{"animation":false,"style":"logo-left"},"sections":[{"fullWidth":true,"backgroundColor":"transparent","columnSeparator":"none","columns":[{"size":5,"blocks":[{"type":"banner","image":"https://cdn.magloft.com/pwa-1/pwa/banner/aea74608-e04a-4649-b817-c45cc439e28e.png","isHidden":true,"title":"Start trial now","action":{"type":"url","href":"https://www.magloft.com/","target":"_blank","pwaSubscriptionId":null,"pwaSubscription":null,"optinId":null,"optin":null}}]}]},{"fullWidth":false,"backgroundColor":null,"columnSeparator":"shadow","columns":[{"size":8.5,"blocks":[{"type":"ad","title":"Advertisement","advertisementIds":[],"adCampaignId":892,"condition":null},{"type":"article-list","condition":null,"color":"#F90505","title":"Top Content","variant":"variant-b","articleIds":[262748,254614,260494,260493,260492,258749],"articles":null},{"type":"article-list","condition":null,"color":"#2873B0","title":"Industry Insights","variant":"variant-b","articleIds":[260492,260493,260494,258746,258745,257361],"articles":null},{"type":"article-category","condition":null,"color":"#F90505","title":"UK News","variant":"variant-c","categoryId":43138,"backgroundColor":null,"image":null,"articles":null,"category":null},{"type":"article-category","condition":null,"color":"#2873B0","title":"Global News","variant":"variant-c","categoryId":43140,"backgroundColor":null,"image":null,"articles":null,"category":null},{"type":"ad","title":"Advertisement","advertisementIds":[1319],"adCampaignId":null,"condition":null},{"type":"article-category","condition":null,"color":"#2873B0","title":"European News","variant":"variant-c","categoryId":43139,"backgroundColor":null,"image":null,"articles":null,"category":null},{"type":"guide-install","color":"#444558","title":"How to Install","condition":null}]},{"size":3.5,"blocks":[{"type":"issue-slider","condition":null,"color":"#2873B0","title":"Latest Editions","issueIds":[52826,52799,52483,52217,51921,51722,51533,51435,51240,51075,45938,45939,45940],"thumbnail":{"style":"full-cover","size":"medium"},"borderRadius":null,"zoomOnHover":true,"issues":null},{"type":"ad","title":"Advertisement","advertisementIds":[2210],"adCampaignId":null,"condition":null},{"type":"cta","condition":null,"icon":"symbol-gift","color":"#FB0505","title":"Newsletters","description":"Sign up to our newsletters and digital magazines","action":{"type":"url","href":"https://curwoodcmsltd.formstack.com/forms/samedan","target":"_blank","pwaSubscriptionId":null,"pwaSubscription":null,"optinId":null,"optin":null}},{"type":"ad","title":"Advertisement","advertisementIds":[2067],"adCampaignId":null,"condition":null},{"type":"cta","condition":null,"icon":"symbol-day","color":"#F90505","title":"Pharmafocus Archive","description":"Browse older editions","action":{"type":"url","href":"https://en.calameo.com/subscriptions/6188508","target":"_blank","pwaSubscriptionId":null,"pwaSubscription":null,"optinId":null,"optin":null}},{"type":"ad","title":"Advertisement","advertisementIds":[],"adCampaignId":1044,"condition":null},{"type":"article-category","condition":null,"color":"#F70707","title":"Appointments","variant":"variant-c","categoryId":43146,"backgroundColor":null,"image":null,"articles":null,"category":null},{"type":"ad","title":"Advertisement","advertisementIds":[2249,1320],"adCampaignId":null,"condition":null}]}]},{"fullWidth":true,"backgroundColor":"transparent","columnSeparator":"none","columns":[{"size":5,"blocks":[{"type":"banner","image":"https://cdn.magloft.com/pwa-664/pwa/banner/1f66e6ea-9b3a-4477-aba1-18abf54619b8.png","isHidden":true,"title":"","action":{"type":"url","href":"http://www.samedanltd.com/","target":"_blank","pwaSubscriptionId":null,"pwaSubscription":null,"optinId":null,"optin":null}}]}]}],"columns":[{"size":8.5,"blocks":[{"type":"ad","title":"Advertisement","advertisementIds":[],"adCampaignId":892,"condition":null},{"type":"article-list","condition":null,"color":"#F90505","title":"Top Content","variant":"variant-b","articleIds":[262748,254614,260494,260493,260492,258749],"articles":null},{"type":"article-list","condition":null,"color":"#2873B0","title":"Industry Insights","variant":"variant-b","articleIds":[260492,260493,260494,258746,258745,257361],"articles":null},{"type":"article-category","condition":null,"color":"#F90505","title":"UK News","variant":"variant-c","categoryId":43138,"backgroundColor":null,"image":null,"articles":null,"category":null},{"type":"article-category","condition":null,"color":"#2873B0","title":"Global News","variant":"variant-c","categoryId":43140,"backgroundColor":null,"image":null,"articles":null,"category":null},{"type":"ad","title":"Advertisement","advertisementIds":[1319],"adCampaignId":null,"condition":null},{"type":"article-category","condition":null,"color":"#2873B0","title":"European News","variant":"variant-c","categoryId":43139,"backgroundColor":null,"image":null,"articles":null,"category":null},{"type":"guide-install","color":"#444558","title":"How to Install","condition":null}]},{"size":3.5,"blocks":[{"type":"issue-slider","condition":null,"color":"#2873B0","title":"Latest Editions","issueIds":[52826,52799,52483,52217,51921,51722,51533,51435,51240,51075,45938,45939,45940],"thumbnail":{"style":"full-cover","size":"medium"},"borderRadius":null,"zoomOnHover":true,"issues":null},{"type":"ad","title":"Advertisement","advertisementIds":[2210],"adCampaignId":null,"condition":null},{"type":"cta","condition":null,"icon":"symbol-gift","color":"#FB0505","title":"Newsletters","description":"Sign up to our newsletters and digital magazines","action":{"type":"url","href":"https://curwoodcmsltd.formstack.com/forms/samedan","target":"_blank","pwaSubscriptionId":null,"pwaSubscription":null,"optinId":null,"optin":null}},{"type":"ad","title":"Advertisement","advertisementIds":[2067],"adCampaignId":null,"condition":null},{"type":"cta","condition":null,"icon":"symbol-day","color":"#F90505","title":"Pharmafocus Archive","description":"Browse older editions","action":{"type":"url","href":"https://en.calameo.com/subscriptions/6188508","target":"_blank","pwaSubscriptionId":null,"pwaSubscription":null,"optinId":null,"optin":null}},{"type":"ad","title":"Advertisement","advertisementIds":[],"adCampaignId":1044,"condition":null},{"type":"article-category","condition":null,"color":"#F70707","title":"Appointments","variant":"variant-c","categoryId":43146,"backgroundColor":null,"image":null,"articles":null,"category":null},{"type":"ad","title":"Advertisement","advertisementIds":[2249,1320],"adCampaignId":null,"condition":null}]}]},"seo":{"home":{"title":"Pharmafocus Magazine - covering pharma and biotech since 1986","description":"Reporting on the pharma industry, drug development \u0026 clinical trials, manufacturing, logistics, market access, and patients.\nFrom breaking stories to interviews with senior executives, we look at regulations \u0026 trends to provide useful market intelligence.","image":"https://cdn.magloft.com/pwa-664/seo/image/270800d8-b1de-41b8-86ad-5d262d2b9adf.png","imageAlt":"Pharmafocus Magazine"},"articles":{"title":"Pharmafocus - Articles","description":"Discover the latest articles published by Pharmafocus. Browse and customize the article feed to your preferences and explore latest trends","image":"https://cdn.magloft.com/pwa-664/seo/image/e7a95017-d617-4914-b4b3-09fcfc683f75.png","imageAlt":"Pharmafocus - Articles"},"issues":{"title":"Pharmafocus - Magazine Issues","description":"Explore the latest issues of Pharmafocus Magazine and keep up to date with the latest industry knowledge","image":"https://cdn.magloft.com/pwa-664/seo/image/b1c374f3-b368-4654-bf00-3b5ed81fe6c2.png","imageAlt":"Pharmafocus - Issues"},"account":{"title":"Pharmafocus - Account","description":"Manage your Pharmafocus Reader Account..","image":"https://cdn.magloft.com/pwa-664/seo/image/5ad881b1-a927-4fb1-b331-81963e9a0f84.png","imageAlt":"Reader Account"}},"strings":{"app":{"title":"Pharmafocus","subtitle":"Pharmaceutical Industry news, analysis and insights"},"social":{"facebook":null,"twitter":"https://twitter.com/Pharmafocus","linkedin":"https://www.linkedin.com/company/pharmafile","youtube":null,"instagram":null},"topMenu":{"title":null,"subtitle":null},"footerMenu":{"title":"Pharmafocus","subtitle":null,"description":null,"email":["info@pharmafile.com"],"privacyUrl":"https://www.pharmafile.com/privacy-policy","termsUrl":"https://www.pharmafile.com/terms-of-service","links":[{"name":"Pharmafile.com","url":"http://www.pharmafile.com"},{"name":"Pharmafile Magazine","url":"https://magazine.pharmafile.com"},{"name":"Samedan","url":"http://www.samedanltd.com"}]},"pages":null},"customFonts":[{"identifier":"trade-gothic-lt"},{"identifier":"trade-gothic-lt-bold"}],"phrases":{},"trialEndAt":null,"bypassSubscription":false},"publication":{"id":14882,"title":"Pharmafocus","properties":{"subtitle":null,"appIcon":"images/defaults/app-icon.png","promotionalText":null,"companyName":null,"emailReplyTo":"","privacyUrl":null,"termsUrl":null}},"categories":[{"id":43138,"slug":"uk-pharma-news","title":"UK News","color":"#444444","issueCount":3,"articleCount":79,"categoryGroupIds":[]},{"id":43139,"slug":"general-news","title":"General News","color":"#444444","issueCount":3,"articleCount":78,"categoryGroupIds":[]},{"id":43140,"slug":"approvals","title":"Approvals","color":"#444444","issueCount":3,"articleCount":159,"categoryGroupIds":[]},{"id":43141,"slug":"research-and-development","title":"R \u0026 D","color":"#444444","issueCount":1,"articleCount":174,"categoryGroupIds":[]},{"id":43143,"slug":"mergers-acquisitions","title":"Mergers \u0026 Acquisitions","color":"#444444","issueCount":0,"articleCount":69,"categoryGroupIds":[]},{"id":43144,"slug":"manufacturing-production","title":"Manufacturing","color":"#444444","issueCount":1,"articleCount":31,"categoryGroupIds":[]},{"id":43149,"slug":"clinical-trials","title":"Clinical Trials","color":"#444444","issueCount":2,"articleCount":33,"categoryGroupIds":[]},{"id":43145,"slug":"industry-insights","title":"Industry Insights","color":"#444444","issueCount":1,"articleCount":56,"categoryGroupIds":[]},{"id":43146,"slug":"appointments","title":"Appointments","color":"#444444","issueCount":2,"articleCount":87,"categoryGroupIds":[]},{"id":43147,"slug":"insider-interviews","title":"Interviews","color":"#444444","issueCount":0,"articleCount":9,"categoryGroupIds":[]},{"id":43148,"slug":"features","title":"Features","color":"#444444","issueCount":0,"articleCount":20,"categoryGroupIds":[]},{"id":43142,"slug":"industry-facts","title":"Industry Facts","color":"#444444","issueCount":2,"articleCount":23,"categoryGroupIds":[]}],"pwaSubscriptions":[],"categoryGroups":[],"slug":"next-generation-sequencing-partnership-announced-between-angle-p","article":{"id":266516,"slug":"next-generation-sequencing-partnership-announced-between-angle-p","issueId":52483,"categoryIds":[43141,43138],"title":"Next-generation sequencing partnership announced between ANGLE plc and NuProbe","description":"Liquid biopsy company ANGLE plc has announced a partnership with NuProbe, a genomics and molecular diagnostics company, to utilise the latter’s pan-cancer next-generation sequencing (NGS) panel.","image":"https://cdn.magloft.com/pdf-import/1125/images/img_10-2.jpg","cover":"https://cdn.magloft.com/publication-14882/screenshots/articles/266516.jpg?ts=1728498303","date":1728601200000,"unlockType":"free","categories":[],"pdfPageId":"AnOofZZMVHNB","visible":true,"showOnToc":true,"bookmark":false,"position":20,"publicationId":14882,"pwaOptinId":null,"seoDescription":"Liquid biopsy company ANGLE plc has announced a partnership with NuProbe, a genomics and molecular diagnostics company","classificationIds":[],"pwaSubscriptionIds":[],"source":"typeloft2","trending":false,"html":"\u003cpage-widget padding=\"16 0 24 0\"\u003e\u003cparagraph-widget padding=\"0 24 0 24\"\u003eResearch \u0026amp; Development\u003c/paragraph-widget\u003e\u003chorizontal-rule-widget padding=\"0 24 0 24\" color=\"#a31f29\"\u003e\u003c/horizontal-rule-widget\u003e\u003cheading-widget padding=\"0 24 16 24\" type=\"h2\"\u003e\u003cspan style=\"font-family: \u0026quot;Roboto Slab\u0026quot;;\" class=\"__bold\"\u003eNext-generation sequencing partnership announced between ANGLE plc and NuProbe\u003c/span\u003e\u003c/heading-widget\u003e\u003cparagraph-widget padding=\"0 24 8 24\"\u003e\u003cspan class=\"__bold\" style=\"color: rgb(28,28,28)\"\u003eLiquid biopsy company ANGLE plc has announced a partnership with NuProbe, a genomics and molecular diagnostics company, to utilise the latter’s pan-cancer next-generation sequencing (NGS) panel. \u003c/span\u003e\u003c/paragraph-widget\u003e\u003cimage-widget padding=\"8 24 16 24\" aspect-ratio=\"1.3542234332425067\" magnify-label=\"center\" source=\"https://cdn.magloft.com/pdf-import/1125/images/img_10-2.jpg#image/jpeg\"\u003e\u003c/image-widget\u003e\u003cparagraph-widget padding=\"0 24 8 24\"\u003eUnder the terms of the agreement, ANGLE has been granted an option for an exclusive global licence to the NGS panel outside of China, for the analysis of circulating tumour cells (CTC) and the dual analysis of CTCs and circulating tumour DNA (ctDNA). This NGS panel enables highly sensitive and specific detection of over 6,500 DNA mutations in 61 clinically relevant genes.\u003c/paragraph-widget\u003e\u003cparagraph-widget padding=\"0 24 8 24\"\u003eFor the first stage of the collaboration, NuProbe will transfer manufacture of the NGS panel to a large-scale manufacturing site, and ANGLE will undertake internal validation of the initial batches.\u003c/paragraph-widget\u003e\u003cparagraph-widget padding=\"0 24 8 24\"\u003eRepeatable, minimally invasive molecular profiling using liquid biopsy analytes has the potential to be used in the future by clinicians for tracking tumour evolution, treatment response, early identification of drug resistance and disease progression.\u003c/paragraph-widget\u003e\u003cparagraph-widget padding=\"0 24 8 24\"\u003eNuProbe chief executive officer Yingshuang Chai, commented: “We are excited to enter into an agreement with ANGLE plc, a world leader in the harvest of CTCs from blood for analysis. NuProbe’s NGS panel is a low-cost, ultrasensitive pan-cancer NGS panel that can accurately detect mutations and has demonstrated robust performance in both CTC and ctDNA sample types. By combining CTC and ctDNA detection, this collaboration will help drive the development of personalised treatment options for cancer patients. We look forward to the development of a strong partnership with ANGLE in the future.”\u003c/paragraph-widget\u003e\u003cparagraph-widget padding=\"0 24 8 24\"\u003eANGLE chief executive officer Andrew Newland, commented: “We are delighted to have signed an agreement with NuProbe, which grants the company an exclusive worldwide licence option (outside of China) to the NGS panel for the analysis of CTCs and dual analysis of CTCs and ctDNA. The company believes that this agreement will enable us to combine the leading CTC harvesting solution with an optimised DNA sequencing panel for analysis of CTCs and dual analysis of CTCs and ctDNA.”\u003c/paragraph-widget\u003e\u003cparagraph-widget padding=\"0 24 8 24\"\u003eANGLE plc and NuProbe are biotech companies based in the UK and the US, respectively.\u003c/paragraph-widget\u003e\u003c/page-widget\u003e","keywordPhrase":"partnership","articleAssets":[{"url":"https://cdn.magloft.com/reader/fonts/roboto-slab.css","extension":"css","contentType":"text/css"},{"url":"https://cdn.magloft.com/reader/fonts/open-sans.css","extension":"css","contentType":"text/css"},{"url":"https://cdn.magloft.com/pdf-import/1125/images/img_10-2.jpg","extension":"jpeg","contentType":"image/jpeg"}]},"publicationId":14882},"__N_SSG":true},"page":"/domains/[domain]/articles/[slug]","query":{"domain":"www.pharmafocus.com","slug":"next-generation-sequencing-partnership-announced-between-angle-p"},"buildId":"1bBCYhXOG7wsYuaBifvjK","isFallback":false,"gsp":true,"scriptLoader":[]}</script></body></html>