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/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0843e93a97ce6bbf970aefb81c05c901ebf544a4-1280x853.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0843e93a97ce6bbf970aefb81c05c901ebf544a4-1280x853.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0843e93a97ce6bbf970aefb81c05c901ebf544a4-1280x853.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0843e93a97ce6bbf970aefb81c05c901ebf544a4-1280x853.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0843e93a97ce6bbf970aefb81c05c901ebf544a4-1280x853.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0843e93a97ce6bbf970aefb81c05c901ebf544a4-1280x853.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0843e93a97ce6bbf970aefb81c05c901ebf544a4-1280x853.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="object-contain" loading="lazy"/></noscript></span></a></div><div class="border-t-gray-100 border-t-2 flex-auto py-2 "><span class="text-sm text-gray-500 py-2">November 26th 2024</span><div class="py-3"><a class="lg:text-[20px] text-[19px] font-[500]" href="/view/researchers-outline-promising-biomarkers-throughout-course-of-ms">Researchers Outline Promising Biomarkers Throughout Course of MS</a></div><div class="pb-2"><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/ajmc-contributor"><i>AJMC Contributor</i></a></span></div></div><a href="/view/researchers-outline-promising-biomarkers-throughout-course-of-ms"><a href="/view/researchers-outline-promising-biomarkers-throughout-course-of-ms"><p class="mt-1 text-gray-800 text-[13px] line-clamp-6 text-hidden">As with other disease states, biomarkers that can provide value across diagnosis, prognosis, and treatment response, have been heavily sought out to help guide optimal treatment decisions throughout the course of disease.</p></a></a></div></div><div class="flex-wrap w-[60%] flex "><a class="flex w-[50%] flex-col sm:pl-[35px] pl-[20px] pb-[35px] " href="/view/study-finds-obesity-may-worsen-multiple-sclerosis-genetic-analysis-points-to-causal-link"><div class="w-full lg:h-[134px] h-[100px] relative bg-default-logo-background "><span 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style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="object-cover" loading="lazy"/></noscript></span></div><div class="jsx-2509189870 content-wrap"><span class="jsx-2509189870 py-3 text-sm text-gray-500 text-left"><i class="jsx-2509189870">November 27th 2024</i></span><div class="jsx-2509189870 w-full h-fit mb-4"><p class="jsx-2509189870 text-[18px] font-bold text-[#000000] text-left line-clamp-3 text-hidden">The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation</p></div><div class="jsx-2509189870 text-left text-[12px] text-[#000] py-6">1 Credit / Cardiology, Neurology</div></div></div></a></div></div></div><div class="flex items-center space-x-4 border-0 border-b border-secondary select-none py-1"><h2 class="text-3xl text-primary">More News</h2></div><div class="flex flex-wrap w-full pb-4"><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-1"></div></div></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/fingolimod-induced-heart-rate-slowing-tied-to-parasympathetic-dominance-in-ms"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/169b2c64631b79d16d4af6026e038334dbb92ce2-4948x3032.jpg?fit=crop&auto=format" alt="Fingolimod | Image Credit: © María Pilar Martínez - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">October 26th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/fingolimod-induced-heart-rate-slowing-tied-to-parasympathetic-dominance-in-ms">Fingolimod-Induced Heart Rate Slowing Tied to Parasympathetic Dominance in MS</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/jared-kaltwasser">Jared Kaltwasser</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/fingolimod-induced-heart-rate-slowing-tied-to-parasympathetic-dominance-in-ms"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">New research helps explain why a subset of patients with relapsing/remitting multiple sclerosis (MS) experience long-term heart rate slowing after taking fingolimod. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/brain-volume-loss-reductions-offer-comparative-tool-for-dmts-in-relapsing-ms"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/9a8f383ae3a2af11ad6c640c91de6a2c1b9dfcea-1200x800.jpg?fit=crop&auto=format" alt="MRI head brain scan | Image Credit: © DedMityay - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">October 24th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/brain-volume-loss-reductions-offer-comparative-tool-for-dmts-in-relapsing-ms">Brain Volume Loss Reductions Offer Comparative Tool for DMTs in Relapsing MS</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/jared-kaltwasser">Jared Kaltwasser</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/brain-volume-loss-reductions-offer-comparative-tool-for-dmts-in-relapsing-ms"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Various therapies have different impacts on brain volume loss in patients with relapsing multiple sclerosis (MS), a new study has found.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex md:hidden justify-center items-center"></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/reframing-ms-the-role-of-support-groups"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/ba4761dda1a4dd900f8537ad106b6e18b4c5bb2f-7065x4347.jpg?fit=crop&auto=format" alt="Support group image | Image Credit: © Rawpixel.com-stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">October 17th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/reframing-ms-the-role-of-support-groups">Reframing MS: The Role of Support Groups</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/gayle-turim-dickstein">Gayle Turim Dickstein</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/reframing-ms-the-role-of-support-groups"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">By attending multiple sclerosis (MS) support group meetings, getting to know members, and sharing their drug-company–sponsored meals, an author delves into the group’s culture and determination to resist being pigeonholed. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/achieving-the-goals-of-value-based-care-for-multiple-sclerosis"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/2ed09f736e1aa332b03ecb73e46961400e47d225-3750x2000.png?fit=crop&auto=format" alt="JT Lew, PharmD, MBA" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">October 1st 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/achieving-the-goals-of-value-based-care-for-multiple-sclerosis">Achieving the Goals of Value-Based Care for Multiple Sclerosis</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/skylar-jeremias">Skylar Jeremias</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/achieving-the-goals-of-value-based-care-for-multiple-sclerosis"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Value-based agreements come with risks and benefits, but a health system’s existing facilities and initiatives can help support the goals associated with them, JT Lew, PharmD, MBA, a managed care pharmacist at MultiCare Health System, explained.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/how-payer-processes-can-impact-ms-therapy-access-dr-jt-lew"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/2ed09f736e1aa332b03ecb73e46961400e47d225-3750x2000.png?fit=crop&auto=format" alt="JT Lew, PharmD, MBA, managed care pharmacist at MultiCare Health System" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">September 24th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/how-payer-processes-can-impact-ms-therapy-access-dr-jt-lew">How Payer Processes Can Impact MS Therapy Access: Dr JT Lew</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/skylar-jeremias">Skylar Jeremias</a><span class="jsx-ad50481d5ee26850 mr-1 ml-[1px]"> </span><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/rose-mcnulty">Rose McNulty</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/how-payer-processes-can-impact-ms-therapy-access-dr-jt-lew"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">JT Lew, PharmD, MBA, managed care pharmacist at MultiCare Health System, spoke to the impacts of processes such as prior authorization and step therapy requirements in the realm of multiple sclerosis (MS).</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/subcutaneous-ocrelizumab-and-hyaluronidase-approved-for-rms-ppms"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/3deabc81aa93f0e49190012e256a274872b958e8-4363x3438.jpg?fit=crop&auto=format" alt="Ocrelizumab and hyaluronidase is now the first and only twice-yearly subcutaneous injection approved for RMS and PPMS. | Image Credit: BHM - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">September 17th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/subcutaneous-ocrelizumab-and-hyaluronidase-approved-for-rms-ppms">Subcutaneous Ocrelizumab and Hyaluronidase Approved for RMS, PPMS</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/rose-mcnulty">Rose McNulty</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/subcutaneous-ocrelizumab-and-hyaluronidase-approved-for-rms-ppms"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Ocrelizumab and hyaluronidase is now the first and only twice-yearly subcutaneous injection approved for relapsing multiple sclerosis (RMS) and primary progressive multiple sclerosis (PPMS).</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-7"></div></div></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/remote-test-reliably-assesses-cognitive-function-in-ms"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/007ecf5e740772c0e34015402e6d5a21cfd3ea90-1200x800.jpg?fit=crop&auto=format" alt="The eSDMT was developed to facilitate more frequent cognitive assessments for people with multiple sclerosis. | Image credit: fizkes - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">September 12th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/remote-test-reliably-assesses-cognitive-function-in-ms">Remote Test Reliably Assesses Cognitive Function in MS</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/rose-mcnulty">Rose McNulty</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/remote-test-reliably-assesses-cognitive-function-in-ms"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">An electronic version of the Symbol-Digit Modalities Test could enable people with multiple sclerosis (MS) to perform frequent remote cognitive assessments independently.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/tolebrutinib-delays-disability-progression-in-non-relapsing-secondary-progressive-ms"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/94ebb7fb518285a2adaac1cf780e1fe58a56b7f3-1280x960.jpg?fit=crop&auto=format" alt="The new results make HERCULES the first and only study to demonstrate reduced CDP in nrSPMS. | Image credit: Juan Gärtner - stock-adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">September 3rd 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/tolebrutinib-delays-disability-progression-in-non-relapsing-secondary-progressive-ms">Tolebrutinib Delays Disability Progression in Nonrelapsing Secondary Progressive MS </a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/rose-mcnulty">Rose McNulty</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/tolebrutinib-delays-disability-progression-in-non-relapsing-secondary-progressive-ms"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">The HERCULES study of tolebrutinib is the first and only to show reduced confirmed disability progression at 6 months in nonrelapsing secondary progressive multiple sclerosis (MS). </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex md:hidden justify-center items-center"></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/dr-jt-lew-explores-the-barriers-to-ms-medication-access"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/2ed09f736e1aa332b03ecb73e46961400e47d225-3750x2000.png?fit=crop&auto=format" alt="AJMC Q&A with JT Lew, PharmD, MBA | Background image credit: ipopba - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">September 3rd 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/dr-jt-lew-explores-the-barriers-to-ms-medication-access">Dr JT Lew Explores the Barriers to MS Medication Access</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/skylar-jeremias">Skylar Jeremias</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/dr-jt-lew-explores-the-barriers-to-ms-medication-access"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">JT Lew, PharmD, MBA, highlights that the primary challenges for patients with multiple sclerosis (MS) in accessing prescribed medications include dealing with the shock of the diagnosis, navigating complex health plan benefits and out-of-pocket costs, and experiencing delays due to insurance barriers.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/stable-mri-in-multiple-sclerosis-reveals-relapses-as-acute-clinical-events"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/c8de0eeb85efb7a8ae47c0737d54a6aa5f4dc709-1200x800.jpg?fit=crop&auto=format" alt="Doctor examining MRI images - New Africa - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">August 21st 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/stable-mri-in-multiple-sclerosis-reveals-relapses-as-acute-clinical-events">Stable MRI in Multiple Sclerosis Reveals Relapses as Acute Clinical Events</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/isabella-ciccone-mph">Isabella Ciccone, MPH</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/stable-mri-in-multiple-sclerosis-reveals-relapses-as-acute-clinical-events"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Acute clinical events with stable MRI were more likely among patients with multiple sclerosis who had longer disease duration, received highly effective disease-modifying therapies, and who presented with fatigue.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/novel-risk-stratification-tool-shows-promise-in-ms"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/967896e5fa1669ecf924ecbe218840f13ffed59b-1200x800.jpg?fit=crop&auto=format" alt="Multiple sclerosis diagnosis | Image credit: Vitalii Vodolazskyi - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">August 16th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/novel-risk-stratification-tool-shows-promise-in-ms">Novel Risk Stratification Tool Shows Promise in MS</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/rose-mcnulty">Rose McNulty</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/novel-risk-stratification-tool-shows-promise-in-ms"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">A predictive tool considering disease duration, age at disease onset, age, and Expanded Disability Status Scale score estimated patients’ risk of transition to secondary progressive multiple sclerosis (MS). </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/online-interventions-can-improve-dietary-behaviors-in-people-with-ms"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/711a407522be790acb61eef75acdb402924eae06-1200x800.jpg?fit=crop&auto=format" alt="The study suggests the codesigned EWWMS program filled a need for reliable and evidence-based nutrition information for patients with MS. | Image credit: Studio Romantic - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">August 16th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/online-interventions-can-improve-dietary-behaviors-in-people-with-ms">Online Interventions Can Improve Dietary Behaviors in People With MS</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/rose-mcnulty">Rose McNulty</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/online-interventions-can-improve-dietary-behaviors-in-people-with-ms"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">A codesigned online nutrition program could potentially fill a need for reliable and evidence-based nutrition information for patients with multiple sclerosis (MS). </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-13"></div></div></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/fatigue-linked-with-reduced-walking-speed-mobility-in-multiple-sclerosis"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/412efd1ef372d87dd396f592726ec02f87dc9c78-5163x3442.jpg?fit=crop&auto=format" alt="Results demonstrate correlations between fatigue and walking speed and mobility among patients with multiple sclerosis. | Image credit: kieferpix - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">Published: August 13th 2024 | Updated: August 14th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/fatigue-linked-with-reduced-walking-speed-mobility-in-multiple-sclerosis">Fatigue Linked With Reduced Walking Speed, Mobility in Multiple Sclerosis</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/rose-mcnulty">Rose McNulty</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/fatigue-linked-with-reduced-walking-speed-mobility-in-multiple-sclerosis"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Study results demonstrated significant correlations between fatigue and reductions in walking speed and mobility among patients with multiple sclerosis.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/healthy-lifestyle-behaviors-linked-to-better-ms-outcomes"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/12dc4f69ba78880089ea42e4764b2918c5cb2a38-1200x774.jpg?fit=crop&auto=format" alt="Healthy behaviors, especially regular exercise and a healthy diet, were associated with better patient-reported outcomes in multiple sclerosis. | Image credit: Daniel Vincek - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">August 7th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/healthy-lifestyle-behaviors-linked-to-better-ms-outcomes">Healthy Lifestyle Behaviors Linked to Better MS Outcomes</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/rose-mcnulty">Rose McNulty</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/healthy-lifestyle-behaviors-linked-to-better-ms-outcomes"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Engaging with healthy lifestyle behaviors, including a healthy diet and physical activity, was associated with better outcomes among patients with multiple sclerosis (MS).</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/less-severe-injective-related-reactions-associated-subcutaneous-ofatumumab-in-ms"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/6e437e2d380932ca45c350e29ce1d49168c33f13-3949x2633.jpg?fit=crop&auto=format" alt="The primary ofatumumab injection reaction is typically development of a fever | image credit: aardenn - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">June 28th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/less-severe-injective-related-reactions-associated-subcutaneous-ofatumumab-in-ms">Subcutaneous Ofatumumab Shows Reduced Injection Reactions in Multiple Sclerosis</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/less-severe-injective-related-reactions-associated-subcutaneous-ofatumumab-in-ms"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">New findings show a similar number of injective-related reactions (IRRs) were reported between the use of ofatumumab (Kesimpta) and ocrelizumab (Ocrevus) in the treatment of multiple sclerosis, but less severe reactions have been associated with ofatumumab. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/study-expands-knowledge-on-dietary-composition-and-ms"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/95ae94b6929d8af813dcc28387af844f6495d93c-6000x4000.jpg?fit=crop&auto=format" alt="Currently, there is no consensus on the best diet for managing MS | image credit: nadianb - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">June 27th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/study-expands-knowledge-on-dietary-composition-and-ms">Study Expands Knowledge on Dietary Composition and MS</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/study-expands-knowledge-on-dietary-composition-and-ms"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">A 2-sample Mendelian randomization study found a potential connection between dietary intake and multiple sclerosis (MS) risk and severity.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex md:hidden justify-center items-center"></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/more-serum-albumin-less-ms-risk-"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/9eb3d04ffc0e5ae34d21ec14e75e47c1c2500da3-3040x2027.jpg?fit=crop&auto=format" alt="Albumin is the most abundant protein in the blood | image credit: jarun011 - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">June 26th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/more-serum-albumin-less-ms-risk-">More Serum Albumin, Less MS Risk?</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/more-serum-albumin-less-ms-risk-"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">An analysis conducted on UK Biobank data suggests a possible association between higher concentrations of serum albumin and a reduced risk of multiple sclerosis (MS). </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/mediterranean-diet-may-reduce-risk-of-multiple-sclerosis"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/150ca87bc9f243af41f9d77178d41e54d8c5d8c7-4500x2924.jpg?fit=crop&auto=format" alt="The Mediterranean diet largely consists of higher fruit, vegetable, legume, and fish intake. | image credit: sonyakamoz - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">June 19th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/mediterranean-diet-may-reduce-risk-of-multiple-sclerosis">Mediterranean Diet May Reduce Risk of Multiple Sclerosis</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/mediterranean-diet-may-reduce-risk-of-multiple-sclerosis"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">A prospective cohort study, using data from the UK Biobank, suggested that the Mediterranean diet could provide benefits to patients with multiple sclerosis. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-19"></div></div></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/gray-matter-atrophy-in-ms-a-strong-indicator-of-progression-study-suggests"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/2d9e8ced1574e071f180b191d06d3be661a34b96-4504x2789.jpg?fit=crop&auto=format" alt="Gray matter is an abundant brain tissue found in the cerebellum, brain stem, and cerebrum | image credit: iushakovsky - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">June 13th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/gray-matter-atrophy-in-ms-a-strong-indicator-of-progression-study-suggests">Gray Matter Atrophy in MS a Strong Indicator of Progression, Study Suggests</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/gray-matter-atrophy-in-ms-a-strong-indicator-of-progression-study-suggests"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">A cross-sectional, prospective study found that gray matter atrophy was more prevalent in patients with more severe progressive multiple sclerosis (MS) compared with those with less severe progressive disease. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/aerobic-exercise-could-benefit-ms-management-further-research-needed"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/496cd463f9a729eb441ba294c63292150d2fff96-6000x3250.jpg?fit=crop&auto=format" alt="Myelin sheath damage in MS concept | image credit: Artur - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">June 7th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/aerobic-exercise-could-benefit-ms-management-further-research-needed">Aerobic Exercise Could Benefit MS Management, Further Research Needed</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/aerobic-exercise-could-benefit-ms-management-further-research-needed"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">A small cohort demonstrated the potential benefits aerobic exercise regimens hold for managing fatigue symptoms in multiple sclerosis (MS), but more studies are needed. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/retinal-vasculature-pathology-linked-with-ms-disease-burden"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/6578e6d8ab1297bed8578f3aaf8f387e6348c06b-5960x4512.jpg?fit=crop&auto=format" alt="Eye imaging | Image credit: Richman Photo - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">May 31st 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/retinal-vasculature-pathology-linked-with-ms-disease-burden">Retinal Vasculature Pathology Linked With MS Disease Burden</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/rose-mcnulty">Rose McNulty</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/retinal-vasculature-pathology-linked-with-ms-disease-burden"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Distinct retinal vessel atrophy patterns may be associated with multiple sclerosis (MS), but further research is needed to assess retinal vessel changes and their underlying role in MS.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/cannabis-treatment-showcases-promising-benefits-for-managing-pain-in-ms"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/67ae126f18f05258de11fd7e57d7b86b560702cf-6720x4480.jpg?fit=crop&auto=format" alt="Cannabis Leaves and Stethoscope | image credit: New Africa - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">May 30th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/cannabis-treatment-showcases-promising-benefits-for-managing-pain-in-ms">Cannabis Treatment Showcases Promising Benefits for Managing Adverse Symptoms of MS</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/cannabis-treatment-showcases-promising-benefits-for-managing-pain-in-ms"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">A real-world study assessed the impact of cannabis-based medicinal products on health-related quality of life in patients with multiple sclerosis (MS). </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/sleep-quality-in-ms-impacted-by-comorbidities-study-finds"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/e262894536805f25f828365656e90ecfa1791cf6-5976x3984.jpg?fit=crop&auto=format" alt="Man Wrestling With Sleeplessness | image credit: mtrlin - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">May 16th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/sleep-quality-in-ms-impacted-by-comorbidities-study-finds">Sleep Quality in MS Impacted by Comorbidities, Study Finds</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/sleep-quality-in-ms-impacted-by-comorbidities-study-finds"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">This cross-sectional analysis demonstrates the impact that comorbidities in multiple sclerosis (MS) have on sleep quality in affected patients. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/serum-neurofilament-light-changes-not-always-apparent-in-active-rrms-study-finds"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/aeac10c553a0dd8e334bf0df8d5549d7442b0972-3200x2133.jpg?fit=crop&auto=format" alt="RRMS AI-Concept | image credit: Evadne - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">May 8th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/serum-neurofilament-light-changes-not-always-apparent-in-active-rrms-study-finds">Serum Neurofilament Light Changes Not Always Apparent in Active RRMS, Study Finds</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/serum-neurofilament-light-changes-not-always-apparent-in-active-rrms-study-finds"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">A prospective study found evidence of serum neurofilament light (sNfL) level increases in patients affected by active forms of relapsing-remitting multiple sclerosis (RRMS); however, these findings were not significant enough to suggest sNfL measurements replace clinical or MRI monitoring of disease activity. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-25"></div></div></div><div class="jsx-ad50481d5ee26850 flex md:hidden justify-center items-center"></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/resistance-training-shows-promise-for-improving-muscle-strength-in-ms"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/fc776329356b143e4109b85ff255ddf86d999036-7952x5304.jpg?fit=crop&auto=format" alt="Resistance Band Exercise Demonstration | image credit: Maridav - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">May 2nd 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/resistance-training-shows-promise-for-improving-muscle-strength-in-ms">Resistance Training Shows Promise for Improving Muscle Strength in MS</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/resistance-training-shows-promise-for-improving-muscle-strength-in-ms"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">A recent meta-analysis that assessed prescribed exercise in managing multiple sclerosis (MS) detailed the benefits of resistance training for improving muscle weakness in this patient population. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/dr-kathy-zackowski-discusses-the-importance-of-rehabilitation-research-and-trials-in-ms"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/613cc8e6d453aef3ba1f2139f8a75f603c00bf33-6016x4016.jpg?fit=crop&auto=format" alt="Clinician Taking Notes on Clinical Trial Concept | image credit: toeytoey - stock.adobe.come" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">April 26th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/dr-kathy-zackowski-discusses-the-importance-of-rehabilitation-research-and-trials-in-ms">Dr Kathy Zackowski Discusses the Importance of Rehabilitation Research and Trials in MS</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a><span class="jsx-ad50481d5ee26850 mr-1 ml-[1px]"> </span><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/brooke-mccormick">Brooke McCormick</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/dr-kathy-zackowski-discusses-the-importance-of-rehabilitation-research-and-trials-in-ms"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Kathy Zackowski, PhD, National MS Society, expresses the inherent value of quality rehabilitation trials for broadening clinical understandings of multiple sclerosis (MS) and bettering patient outcomes. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/dr-dalia-rotstein-physicians-must-be-aware-ms-affects-people-of-all-backgrounds"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/a9985dc92f57f038d1879c5c4c61b4df4bbb9ecd-5396x2780.jpg?fit=crop&auto=format" alt="Social Diversity, Representation Concept | image credit: undrey - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">April 24th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/dr-dalia-rotstein-physicians-must-be-aware-ms-affects-people-of-all-backgrounds">Dr Dalia Rotstein: Physicians Must Be Aware MS Affects People of All Backgrounds</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a><span class="jsx-ad50481d5ee26850 mr-1 ml-[1px]"> </span><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/brooke-mccormick">Brooke McCormick</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/dr-dalia-rotstein-physicians-must-be-aware-ms-affects-people-of-all-backgrounds"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Dalia Rotstein, MD, MPH, emphazises the importance of awareness that multiple sclerosis (MS) impacts patients from various backgrounds as clinicians think through ways to improve access to care and research efforts in MS. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/dr-krystyn-van-vliet-on-tackling-scalability-cost-when-using-3d-platforms-for-ms-drug-discovery"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/6d33afc54894990d0fec003b54d4a788436ac39a-2878x1614.png?fit=crop&auto=format" alt="dr krystyn van vliet" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">April 7th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/dr-krystyn-van-vliet-on-tackling-scalability-cost-when-using-3d-platforms-for-ms-drug-discovery">Dr Krystyn Van Vliet on Tackling Scalability, Cost When Using 3D Platforms for MS Drug Discovery </a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/brooke-mccormick">Brooke McCormick</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/dr-krystyn-van-vliet-on-tackling-scalability-cost-when-using-3d-platforms-for-ms-drug-discovery"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Krystyn Van Vliet, PhD, of Cornell University, discusses the scalability of 3D platforms in multiple sclerosis (MS) drug discovery and compares their costs with those of other drug discovery methods.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/the-promise-of-frexalimab-in-ms-part-3"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/a140659a2f322779e8574e67ac55a2223ef2e0c2-2880x1618.jpg?fit=crop&auto=format" alt="Patrick Vermersch, MD, PhD" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">March 28th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/the-promise-of-frexalimab-in-ms-part-3">The Promise of Frexalimab in MS: Part 3</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/the-promise-of-frexalimab-in-ms-part-3"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Patrick Vermersch, MD, PhD, University of Lille, France details the adverse events observed in the frexalimab trials and the next steps necessary to establish frexalimab as a standard of care in multiple sclerosis (MS) in the third and final part of an interview. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/distinguishing-biomarkers-identified-in-ms"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/df41a984c2b36fb0da6a87d7e872e69c998b500d-5500x2700.jpg?fit=crop&auto=format" alt="Neurologic Disease MS Concept | image credit: ralwel - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">March 19th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/distinguishing-biomarkers-identified-in-ms">Distinguishing Biomarkers Identified in MS Outcomes</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/distinguishing-biomarkers-identified-in-ms"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Results from this cohort study found that levels of glial fibrillary acid protein, cerebral spinal fluid, and neurofilament heavy chain are distinguishable biomarkers that are associated with disease outcomes in multiple sclerosis (MS). </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div></div><div class="w-full text-center flex justify-center pb-24"><a class="px-4 py-2 border-y border-r bg-primary text-white" href="/compendium/multiple-sclerosis?page=1">1</a><a class="px-4 py-2 border-y border-r " href="/compendium/multiple-sclerosis?page=2">2</a><a class="px-4 py-2 border-y border-r " href="/compendium/multiple-sclerosis?page=3">3</a><a class="px-4 py-2 border-y border-r " href="/compendium/multiple-sclerosis?page=4">4</a><a class="px-4 py-2 border-y border-r " href="/compendium/multiple-sclerosis?page=5">5</a><a class="px-4 py-2 border-y border-r " href="/compendium/multiple-sclerosis?page=6">6</a><a class="px-4 py-2 border-y border-r " href="/compendium/multiple-sclerosis?page=7">7</a><a class="px-4 py-2 border-y border-r " href="/compendium/multiple-sclerosis?page=8">8</a><div class="px-4 py-2 border-y border-r">...</div><a class="px-4 py-2 border-y 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","updatedOn":null,"contentCategory":{"_createdAt":"2020-04-03T20:03:53Z","_rev":"Q2ZL7ihdIB33NiMMcGccmh","_type":"contentCategory","name":"Articles","_id":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2","_updatedAt":"2023-09-29T14:32:27Z"}},{"title":"Online Interventions Can Improve Dietary Behaviors in People With MS","url":"online-interventions-can-improve-dietary-behaviors-in-people-with-ms","thumbnail":{"caption":"The study suggests the codesigned EWWMS program filled a need for reliable and evidence-based nutrition information for patients with MS. | Image credit: Studio Romantic - stock.adobe.com","asset":{"_ref":"image-711a407522be790acb61eef75acdb402924eae06-1200x800-jpg","_type":"reference"},"_type":"mainImage","alt":"The study suggests the codesigned EWWMS program filled a need for reliable and evidence-based nutrition information for patients with MS. | Image credit: Studio Romantic - stock.adobe.com"},"published":"2024-08-16T12:44:03.260Z","contentCategory":{"_rev":"Q2ZL7ihdIB33NiMMcGccmh","_type":"contentCategory","name":"Articles","_id":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2","_updatedAt":"2023-09-29T14:32:27Z","_createdAt":"2020-04-03T20:03:53Z"},"authors":[{"displayName":"Rose McNulty","url":"rose-mcnulty"}],"_id":"92dbca91-5a97-4c6f-90d1-aae0a3285bf5","updatedOn":null,"factCheckAuthors":null,"summary":"A codesigned online nutrition program could potentially fill a need for reliable and evidence-based nutrition information for patients with multiple sclerosis (MS). "},{"summary":"Study results demonstrated significant correlations between fatigue and reductions in walking speed and mobility among patients with multiple sclerosis.","contentCategory":{"_type":"contentCategory","name":"Articles","_id":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2","_updatedAt":"2023-09-29T14:32:27Z","_createdAt":"2020-04-03T20:03:53Z","_rev":"Q2ZL7ihdIB33NiMMcGccmh"},"authors":[{"displayName":"Rose McNulty","url":"rose-mcnulty"}],"_id":"d7152133-b7a0-4d81-b5a0-537798fdc02b","title":"Fatigue Linked With Reduced Walking Speed, Mobility in Multiple Sclerosis","url":"fatigue-linked-with-reduced-walking-speed-mobility-in-multiple-sclerosis","thumbnail":{"asset":{"_ref":"image-412efd1ef372d87dd396f592726ec02f87dc9c78-5163x3442-jpg","_type":"reference"},"_type":"mainImage","alt":"Results demonstrate correlations between fatigue and walking speed and mobility among patients with multiple sclerosis. | Image credit: kieferpix - stock.adobe.com","caption":"Results demonstrate correlations between fatigue and walking speed and mobility among patients with multiple sclerosis. | Image credit: kieferpix - stock.adobe.com"},"published":"2024-08-13T21:23:27.879Z","updatedOn":"2024-08-14T13:52:38.623Z","factCheckAuthors":null},{"url":"healthy-lifestyle-behaviors-linked-to-better-ms-outcomes","summary":"Engaging with healthy lifestyle behaviors, including a healthy diet and physical activity, was associated with better outcomes among patients with multiple sclerosis (MS).","_id":"fadf3b64-97ac-468d-ba9b-b9284b23fba2","title":"Healthy Lifestyle Behaviors Linked to Better MS Outcomes","updatedOn":null,"contentCategory":{"_rev":"Q2ZL7ihdIB33NiMMcGccmh","_type":"contentCategory","name":"Articles","_id":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2","_updatedAt":"2023-09-29T14:32:27Z","_createdAt":"2020-04-03T20:03:53Z"},"authors":[{"displayName":"Rose McNulty","url":"rose-mcnulty"}],"factCheckAuthors":null,"thumbnail":{"asset":{"_ref":"image-12dc4f69ba78880089ea42e4764b2918c5cb2a38-1200x774-jpg","_type":"reference"},"_type":"mainImage","alt":"Healthy behaviors, especially regular exercise and a healthy diet, were associated with better patient-reported outcomes in multiple sclerosis. | Image credit: Daniel Vincek - stock.adobe.com","caption":"Healthy behaviors, especially regular exercise and a healthy diet, were associated with better patient-reported outcomes in multiple sclerosis. | Image credit: Daniel Vincek - stock.adobe.com"},"published":"2024-08-07T22:53:20.617Z"},{"title":"Subcutaneous Ofatumumab Shows Reduced Injection Reactions in Multiple Sclerosis","url":"less-severe-injective-related-reactions-associated-subcutaneous-ofatumumab-in-ms","summary":"New findings show a similar number of injective-related reactions (IRRs) were reported between the use of ofatumumab (Kesimpta) and ocrelizumab (Ocrevus) in the treatment of multiple sclerosis, but less severe reactions have been associated with ofatumumab. 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"},{"summary":"A prospective cohort study, using data from the UK Biobank, suggested that the Mediterranean diet could provide benefits to patients with multiple sclerosis. ","published":"2024-06-19T16:40:00.000Z","contentCategory":{"name":"Articles","_id":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2","_updatedAt":"2023-09-29T14:32:27Z","_createdAt":"2020-04-03T20:03:53Z","_rev":"Q2ZL7ihdIB33NiMMcGccmh","_type":"contentCategory"},"authors":[{"displayName":"Kyle Munz","url":"kyle-munz"}],"thumbnail":{"_type":"mainImage","alt":"The Mediterranean diet largely consists of higher fruit, vegetable, legume, and fish intake. | image credit: sonyakamoz - stock.adobe.com","caption":"The Mediterranean diet largely consists of higher fruit, vegetable, legume, and fish intake. | image credit: sonyakamoz - stock.adobe.com","asset":{"_ref":"image-150ca87bc9f243af41f9d77178d41e54d8c5d8c7-4500x2924-jpg","_type":"reference"}},"title":"Mediterranean Diet May Reduce Risk of Multiple Sclerosis","url":"mediterranean-diet-may-reduce-risk-of-multiple-sclerosis","updatedOn":null,"factCheckAuthors":null,"_id":"5a130b4b-5a49-454d-aa3c-337092d61296"},{"url":"gray-matter-atrophy-in-ms-a-strong-indicator-of-progression-study-suggests","summary":"A cross-sectional, prospective study found that gray matter atrophy was more prevalent in patients with more severe progressive multiple sclerosis (MS) compared with those with less severe progressive disease. ","authors":[{"displayName":"Kyle Munz","url":"kyle-munz"}],"_id":"129545eb-fba6-4795-829d-8df78c043e35","title":"Gray Matter Atrophy in MS a Strong Indicator of Progression, Study Suggests","thumbnail":{"_type":"mainImage","alt":"Gray matter is an abundant brain tissue found in the cerebellum, brain stem, and cerebrum | image credit: iushakovsky - stock.adobe.com","caption":"Gray matter is an abundant brain tissue found in the cerebellum, brain stem, and cerebrum | image credit: iushakovsky - stock.adobe.com","asset":{"_ref":"image-2d9e8ced1574e071f180b191d06d3be661a34b96-4504x2789-jpg","_type":"reference"}},"published":"2024-06-13T18:12:10.500Z","updatedOn":null,"contentCategory":{"name":"Articles","_id":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2","_updatedAt":"2023-09-29T14:32:27Z","_createdAt":"2020-04-03T20:03:53Z","_rev":"Q2ZL7ihdIB33NiMMcGccmh","_type":"contentCategory"},"factCheckAuthors":null},{"_id":"2c71ffc9-99a3-43b0-8872-127fc8c591b8","title":"Aerobic Exercise Could Benefit MS Management, Further Research Needed","summary":"A small cohort demonstrated the potential benefits aerobic exercise regimens hold for managing fatigue symptoms in multiple sclerosis (MS), but more studies are needed. ","authors":[{"displayName":"Kyle Munz","url":"kyle-munz"}],"url":"aerobic-exercise-could-benefit-ms-management-further-research-needed","thumbnail":{"_type":"mainImage","alt":"Myelin sheath damage in MS concept | image credit: Artur - stock.adobe.com","caption":"Myelin sheath damage in MS concept | image credit: Artur - stock.adobe.com","asset":{"_ref":"image-496cd463f9a729eb441ba294c63292150d2fff96-6000x3250-jpg","_type":"reference"}},"published":"2024-06-07T15:16:00.000Z","updatedOn":null,"contentCategory":{"_type":"contentCategory","name":"Articles","_id":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2","_updatedAt":"2023-09-29T14:32:27Z","_createdAt":"2020-04-03T20:03:53Z","_rev":"Q2ZL7ihdIB33NiMMcGccmh"},"factCheckAuthors":null},{"factCheckAuthors":null,"_id":"b5b5bf3b-89c1-4b14-878b-c1f9cd76429a","summary":"Distinct retinal vessel atrophy patterns may be associated with multiple sclerosis (MS), but further research is needed to assess retinal vessel changes and their underlying role in MS.","published":"2024-05-31T18:43:25.716Z","authors":[{"displayName":"Rose McNulty","url":"rose-mcnulty"}],"contentCategory":{"_createdAt":"2020-04-03T20:03:53Z","_rev":"Q2ZL7ihdIB33NiMMcGccmh","_type":"contentCategory","name":"Articles","_id":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2","_updatedAt":"2023-09-29T14:32:27Z"},"title":"Retinal Vasculature Pathology Linked With MS Disease Burden","url":"retinal-vasculature-pathology-linked-with-ms-disease-burden","thumbnail":{"_type":"mainImage","alt":"Eye imaging | Image credit: Richman Photo - stock.adobe.com","caption":"Eye imaging | Image credit: Richman Photo - stock.adobe.com","asset":{"_ref":"image-6578e6d8ab1297bed8578f3aaf8f387e6348c06b-5960x4512-jpg","_type":"reference"}},"updatedOn":null},{"url":"cannabis-treatment-showcases-promising-benefits-for-managing-pain-in-ms","summary":"A real-world study assessed the impact of cannabis-based medicinal products on health-related quality of life in patients with multiple sclerosis (MS). ","authors":[{"displayName":"Kyle Munz","url":"kyle-munz"}],"factCheckAuthors":null,"title":"Cannabis Treatment Showcases Promising Benefits for Managing Adverse Symptoms of MS","thumbnail":{"caption":"Cannabis Leaves and Stethoscope | image credit: New Africa - stock.adobe.com","asset":{"_ref":"image-67ae126f18f05258de11fd7e57d7b86b560702cf-6720x4480-jpg","_type":"reference"},"_type":"mainImage","alt":"Cannabis Leaves and Stethoscope | image credit: New Africa - stock.adobe.com"},"published":"2024-05-30T14:41:00.000Z","updatedOn":null,"contentCategory":{"_createdAt":"2020-04-03T20:03:53Z","_rev":"Q2ZL7ihdIB33NiMMcGccmh","_type":"contentCategory","name":"Articles","_id":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2","_updatedAt":"2023-09-29T14:32:27Z"},"_id":"59a21aa7-1e6b-498f-b2ae-967c0556084e"},{"_id":"5e4637a4-7a56-45f9-8faf-a7c723f577aa","title":"Sleep Quality in MS Impacted by Comorbidities, Study Finds","thumbnail":{"_type":"mainImage","alt":"Man Wrestling With Sleeplessness | image credit: mtrlin - stock.adobe.com","caption":"Man Wrestling With Sleeplessness | image credit: mtrlin - stock.adobe.com","asset":{"_ref":"image-e262894536805f25f828365656e90ecfa1791cf6-5976x3984-jpg","_type":"reference"}},"summary":"This cross-sectional analysis demonstrates the impact that comorbidities in multiple sclerosis (MS) have on sleep quality in affected patients. ","updatedOn":null,"contentCategory":{"_rev":"Q2ZL7ihdIB33NiMMcGccmh","_type":"contentCategory","name":"Articles","_id":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2","_updatedAt":"2023-09-29T14:32:27Z","_createdAt":"2020-04-03T20:03:53Z"},"factCheckAuthors":null,"url":"sleep-quality-in-ms-impacted-by-comorbidities-study-finds","published":"2024-05-16T16:15:00.000Z","authors":[{"displayName":"Kyle Munz","url":"kyle-munz"}]},{"url":"serum-neurofilament-light-changes-not-always-apparent-in-active-rrms-study-finds","contentCategory":{"_id":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2","_updatedAt":"2023-09-29T14:32:27Z","_createdAt":"2020-04-03T20:03:53Z","_rev":"Q2ZL7ihdIB33NiMMcGccmh","_type":"contentCategory","name":"Articles"},"authors":[{"displayName":"Kyle Munz","url":"kyle-munz"}],"title":"Serum Neurofilament Light Changes Not Always Apparent in Active RRMS, Study Finds","thumbnail":{"_type":"mainImage","alt":"RRMS AI-Concept | image credit: Evadne - stock.adobe.com","caption":"RRMS AI-Concept | image credit: Evadne - stock.adobe.com","asset":{"_ref":"image-aeac10c553a0dd8e334bf0df8d5549d7442b0972-3200x2133-jpg","_type":"reference"}},"summary":"A prospective study found evidence of serum neurofilament light (sNfL) level increases in patients affected by active forms of relapsing-remitting multiple sclerosis (RRMS); however, these findings were not significant enough to suggest sNfL measurements replace clinical or MRI monitoring of disease activity. ","published":"2024-05-08T15:00:00.000Z","updatedOn":null,"factCheckAuthors":null,"_id":"60d0a457-1b34-4414-ac74-999e420d1ca9"},{"title":"Resistance Training Shows Promise for Improving Muscle Strength in MS","url":"resistance-training-shows-promise-for-improving-muscle-strength-in-ms","updatedOn":null,"authors":[{"displayName":"Kyle Munz","url":"kyle-munz"}],"_id":"033bc1f9-2e4b-4c4a-82fc-1c7dae56b63a","thumbnail":{"_type":"mainImage","alt":"Resistance Band Exercise Demonstration | image credit: Maridav - stock.adobe.com","caption":"Resistance Band Exercise Demonstration | image credit: Maridav - stock.adobe.com","asset":{"_ref":"image-fc776329356b143e4109b85ff255ddf86d999036-7952x5304-jpg","_type":"reference"}},"summary":"A recent meta-analysis that assessed prescribed exercise in managing multiple sclerosis (MS) detailed the benefits of resistance training for improving muscle weakness in this patient population. ","published":"2024-05-02T18:48:56.280Z","contentCategory":{"_createdAt":"2020-04-03T20:03:53Z","_rev":"Q2ZL7ihdIB33NiMMcGccmh","_type":"contentCategory","name":"Articles","_id":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2","_updatedAt":"2023-09-29T14:32:27Z"},"factCheckAuthors":null},{"_id":"d4c1dd14-72dc-4cd5-9e70-d7050cc7c856","published":"2024-04-26T16:20:00.000Z","updatedOn":null,"contentCategory":{"_updatedAt":"2023-09-29T14:32:27Z","_createdAt":"2020-04-03T20:03:53Z","_rev":"Q2ZL7ihdIB33NiMMcGccmh","_type":"contentCategory","name":"Articles","_id":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2"},"authors":[{"displayName":"Kyle Munz","url":"kyle-munz"},{"displayName":"Brooke McCormick","url":"brooke-mccormick"}],"title":"Dr Kathy Zackowski Discusses the Importance of Rehabilitation Research and Trials in MS","url":"dr-kathy-zackowski-discusses-the-importance-of-rehabilitation-research-and-trials-in-ms","thumbnail":{"caption":"Clinician Taking Notes on Clinical Trial Concept | image credit: toeytoey - stock.adobe.come","asset":{"_type":"reference","_ref":"image-613cc8e6d453aef3ba1f2139f8a75f603c00bf33-6016x4016-jpg"},"_type":"mainImage","alt":"Clinician Taking Notes on Clinical Trial Concept | image credit: toeytoey - stock.adobe.come"},"summary":"Kathy Zackowski, PhD, National MS Society, expresses the inherent value of quality rehabilitation trials for broadening clinical understandings of multiple sclerosis (MS) and bettering patient outcomes. ","factCheckAuthors":null},{"published":"2024-04-24T20:20:11.648Z","authors":[{"displayName":"Kyle Munz","url":"kyle-munz"},{"displayName":"Brooke McCormick","url":"brooke-mccormick"}],"url":"dr-dalia-rotstein-physicians-must-be-aware-ms-affects-people-of-all-backgrounds","title":"Dr Dalia Rotstein: Physicians Must Be Aware MS Affects People of All Backgrounds","thumbnail":{"_type":"mainImage","alt":"Social Diversity, Representation Concept | image credit: undrey - stock.adobe.com","caption":"Social Diversity, Representation Concept | image credit: undrey - stock.adobe.com","asset":{"_ref":"image-a9985dc92f57f038d1879c5c4c61b4df4bbb9ecd-5396x2780-jpg","_type":"reference"}},"summary":"Dalia Rotstein, MD, MPH, emphazises the importance of awareness that multiple sclerosis (MS) impacts patients from various backgrounds as clinicians think through ways to improve access to care and research efforts in MS. 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","ExcludeFromPubMedXML":false,"published":"2024-04-12T16:33:00.000Z","body":[{"videoID":"6350630015112","disableAutoPlayVideo":false,"source":"brightcove","_key":"8daad26d5bd3","videoObject":{"videoTitle":"Dr Ari Green Gives Insights Into Promising Remyelination Therapies and Factors Influencing Patient Outcomes","thumbnail":{"_type":"image","asset":{"_ref":"image-ef1badaf5b526220dc06d571ced73504ea66c411-2880x1614-png","_type":"reference"}},"videoDuration":"3 minutes 24 seconds","videoDescription":"Dr Ari Green discusses promising remyelination therapies and factors influencing patient outcomes in multiple sclerosis","_type":"videoDetails"},"experienceID":"6350630015112","_type":"video"},{"_type":"block","style":"normal","_key":"9f9b9b475fd3","markDefs":[{"blank":true,"_type":"link","href":"https://www.ajmc.com/conference/aactrims-americas-committee-for-treatment-and-research-in-multiple-sclerosis","_key":"652dd6c0c73d"}],"children":[{"marks":[],"text":"Ari Green, MD, chief of the division of neuroimmunology and glial biology at the University of California, San Francisco, presented on remyelination, among other related topics, at this year’s ","_key":"483d4e1b85130","_type":"span"},{"_type":"span","marks":["652dd6c0c73d"],"text":"Americas Committee for Treatment and Research in MS (ACTRIMS) Forum 2024","_key":"483d4e1b85131"},{"_key":"483d4e1b85132","_type":"span","marks":[],"text":" in his session titled, “Barriers in Neural Repair.”"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"0be00b3c8b7c0"}],"_type":"block","style":"normal","_key":"9ea892efa48b"},{"_type":"block","style":"normal","_key":"d1cfd2710da4","markDefs":[{"_key":"6e4956728f6c","nofollow":false,"blank":true,"_type":"link","href":"https://www.ajmc.com/compendium/multiple-sclerosis"}],"children":[{"_type":"span","marks":[],"text":"Here, Green discusses the promising remyelination therapies that have emerged in clinical trials over the years, as well as explores the patient and disease factors that can have am impact on individual responses to treatment in ","_key":"21e1de764d320"},{"marks":["6e4956728f6c"],"text":"multiple sclerosis (MS)","_key":"4c43455cab36","_type":"span"},{"text":".","_key":"a16ee30dbfd2","_type":"span","marks":[]}]},{"_key":"c4d746a861e0","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"bee948db6d120"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"text":"Transcript","_key":"e14fc1c7125b0","_type":"span","marks":["strong","underline"]}],"_type":"block","style":"normal","_key":"7ef64b8bf3bc"},{"children":[{"_type":"span","marks":["strong"],"text":"In clinical trials, what remyelination therapies have shown positive results or potential efficacy in improving myelin repair in patients with MS?","_key":"0f2c517ed09c0"}],"_type":"block","style":"normal","_key":"23b83c083209","markDefs":[]},{"children":[{"_key":"0ea03011bfbe0","_type":"span","marks":[],"text":"So at this point, the one we've worked on that has shown the most capacity for validation and confirmation of the result, that's clemastine. That's a drug that, although it wasn't designed for this purpose, acts on a particular receptor known as the M1 receptor. Now, it's a little bit of a dirty drug in that it acts on multiple muscarinic receptors, as well as histamine receptors. It's not designed for this purpose, but it is the one that multiple laboratories have been able to confirm since we first identified it."}],"_type":"block","style":"normal","_key":"78d1cc43679e","markDefs":[]},{"_type":"block","style":"normal","_key":"99b74ebb5aeb","markDefs":[],"children":[{"_type":"span","marks":[],"text":"There are a few other drugs that have also shown effect. There are other drugs in that same pathway, the antimuscarinic pathway, that have shown some effect. In addition, drugs in the pathway known as selective estrogen receptor modulators have shown effect. The challenge is always making sure we have a therapy that works in combination with a tolerability profile that would make them useful for patient use.","_key":"86876c9cd6850"}]},{"children":[{"_type":"span","marks":[],"text":"So the ones that have been tested robustly in people are limited. So clemastine has been tested in 1 successful clinical trial; another drug known as bexarotene was tested by a group at Cambridge. That drug didn't meet its primary clinical end point, but actually on the same clinical end point that we used in our clemastine trials, did appear to show efficacy. That drug works on a completely different pathway known as RSR gamma.","_key":"cf8704fdf59e"}],"_type":"block","style":"normal","_key":"39b336287a13","markDefs":[]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"But in terms of the drugs that have shown clinical effect, there's a number of other drugs that have been tested that weren't capable of showing a robust effect. But part of that is sometimes, it may not be the drug; it might be the means by which we assess whether or not the drug worked. So this always happens in concert where we work on the therapy and we work on the measurements at the same time in conjunction with one another.","_key":"28b8951e9746"}],"_type":"block","style":"normal","_key":"b833f67c16d8"},{"markDefs":[],"children":[{"text":"","_key":"8d49ea6de1a80","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"b44e10dbc0d5"},{"markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"What patient-specific factors, like disease subtype, MS duration, and individual responsiveness, influence the efficacy of remyelination treatments?","_key":"120f4bd52a6e0"}],"_type":"block","style":"normal","_key":"c91157c72d92"},{"children":[{"_type":"span","marks":[],"text":"Definitely this issue of individual patient response is something that we need to spend time working on and identify individual factors, whether that even be related to genetics or it be related to other issues—diet or environment—that may influence people's responsiveness to therapeutics. But in addition to that, other things that might be predictive of people who are earlier in the course of disease and people who are younger are more likely to respond to therapy.","_key":"33a79fa83ba30"}],"_type":"block","style":"normal","_key":"d41160e24c87","markDefs":[]},{"style":"normal","_key":"cc4b9dec1ce1","markDefs":[],"children":[{"_type":"span","marks":[],"text":"We also think that at the very least for chronic use of these drugs, we have to keep the inflammation at bay. So people should remain on their immunomodulatory disease modifying therapies, in conjunction with remyelinating therapies. That's kind of what I think, and I think most of the field thinks, is ultimately the most likely scenario for us in terms of treatment.","_key":"586a96016627"}],"_type":"block"},{"style":"normal","_key":"8de990e675f1","markDefs":[],"children":[{"_key":"ebf7243de5da","_type":"span","marks":[],"text":"It goes without saying that the earlier you work at this, the more axons are available, the more likely remyelination is to be the most robust and potentially the most easy to detect."}],"_type":"block"}],"_createdAt":"2024-04-11T18:04:08Z","link":"/view/dr-ari-green-on-promising-remyelination-therapies-and-patient-outcomes-in-ms","_rev":"wpA5PqFN6itrAEJI1ugZHR","title":"Dr Ari Green on Promising Remyelination Therapies and Patient Outcomes in MS","seoTag":["multiple sclerosis","MS","remyelination"],"_type":"article","url":{"current":"dr-ari-green-on-promising-remyelination-therapies-and-patient-outcomes-in-ms","_type":"slug"},"updatedOn":null,"source":null,"factCheckAuthorMapping":null},{"authorMapping":[{"lastName":"McCormick","displayName":"Brooke McCormick","_id":"00af9d05-a2c4-4451-a6d1-0e28b08cbb65","biography":[{"_type":"block","style":"normal","_key":"936ecf4b7f0c","markDefs":[],"children":[{"marks":[],"text":"Brooke is an assistant editor for ","_key":"8d68730a8da0","_type":"span"},{"_key":"730c46c984c9","_type":"span","marks":["em"],"text":"The American Journal of Managed Care"},{"_type":"span","marks":[],"text":"® (","_key":"0b218fbaa571"},{"marks":["em"],"text":"AJMC","_key":"b1b5b3d9cff0","_type":"span"},{"_type":"span","marks":[],"text":"®). 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What approaches could be used to address these challenges?","_key":"ba09441fb5010"}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"7f573f4ae0010"}],"_type":"block","style":"normal","_key":"d092df93faa4"},{"children":[{"_type":"span","marks":[],"text":"There are definitely issues in recruiting and maintaining minority populations. Some of them are that people are often not asked to be involved in clinical trials. Also, people don't know where to find out about clinical trials, so many people with MS are not treated at our traditional MS centers. Many of them are treated in the community, so they don't know about clinical research, where it's being conducted, and how to get involved with it. ","_key":"8f8ef81c7984"}],"_type":"block","style":"normal","_key":"5ff570a14d80","markDefs":[]},{"_key":"f4655ba87d56","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"bced6cffa770"}],"_type":"block","style":"normal"},{"style":"normal","_key":"0334a79439c8","markDefs":[],"children":[{"_type":"span","marks":[],"text":"I think it's very important for us to address those issues. I think we also have to address issues of mistrust or distrust within the community. There have been a lot of egregious things that have happened across many decades within the scientific community that have been detrimental to many different populations. So, I think it's very important for us to address those, but also, as researchers, to look at the way we're conducting research to make sure that we are being inclusive of these populations.","_key":"a44a8502c048"}],"_type":"block"},{"children":[{"text":"","_key":"ae378cfbaa73","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"cbf0ac06d73f","markDefs":[]},{"_key":"dc240cfcf4af","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"What strategies can be used to ensure that clinical trials are accessible to patients from different regions, including rural and underserved areas?","_key":"9133b5f888290"}],"_type":"block","style":"normal"},{"_key":"66688848cbe9","markDefs":[],"children":[{"text":"","_key":"4c8a4cbfa071","_type":"span","marks":[]}],"_type":"block","style":"normal"},{"_key":"631492f756af","markDefs":[],"children":[{"_type":"span","marks":[],"text":"There are lots of different strategies that can be employed, and I think it's important to recognize that this is a multistakeholder approach to really get this done. Certainly, we have to make sure that patients are educated about trials, but we can't put the onus on patients to do all of the work. ","_key":"72bdfe0556ff0"}],"_type":"block","style":"normal"},{"style":"normal","_key":"b1ba47099248","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"667041d79d9e"}],"_type":"block"},{"style":"normal","_key":"013a565d8d1b","markDefs":[],"children":[{"_type":"span","marks":[],"text":"We as a scientific community have to look at the way that we are creating our trials. Are we automatically excluding groups of people due to extremely or excessively restrictive inclusion and exclusion criteria? Are we making sure that if there are things that can be done remotely, that they're being done remotely? ","_key":"1b619574ccd9"}],"_type":"block"},{"style":"normal","_key":"b8fa9d7912e5","markDefs":[],"children":[{"text":"","_key":"48abe87eaa5d","_type":"span","marks":[]}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Also, from an industry perspective, we have to look at where we're conducting the research. If we are not conducting research in communities to reach the people that we say we're trying to serve, and we're only reaching large urban centers, we're going to miss out on a lot of people who may be very willing to participate but unable to access trials because of that.","_key":"3095776166ed"}],"_type":"block","style":"normal","_key":"9b774a4903cc"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"a1ec14672983"}],"_type":"block","style":"normal","_key":"b5b44ef0b25d"},{"style":"normal","_key":"ba45119f7265","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"How can clinical trial designs be optimized to account for potential disparities in health outcomes among different demographic groups?","_key":"feed6adb617b0"}],"_type":"block"},{"markDefs":[],"children":[{"text":"","_key":"59763dc88fe0","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"8f541f09a4f1"},{"_key":"6c6066826ccb","markDefs":[],"children":[{"_type":"span","marks":[],"text":"I think it's important when looking at how we design clinical trials to try to be innovative and think outside of the box. If there is nothing that the pandemic has taught us, it's that we can do a lot of things remotely that we thought we could not do remotely. ","_key":"1fbc24c2f8da0"}],"_type":"block","style":"normal"},{"style":"normal","_key":"18ff2a73208b","markDefs":[],"children":[{"marks":[],"text":"","_key":"3a61e4a22217","_type":"span"}],"_type":"block"},{"children":[{"_type":"span","marks":[],"text":"So, looking at ways to decrease the burden on patients. It can be very expensive for someone to be involved in a clinical trial if they have to drive or get transportation to whatever center for blood draws, MRIs, for all of these different studies. If they have to find child care, elder care, if they have to miss their jobs. These are things that are expenses to patients, so we have to look at ways to offset that cost to make things more accessible. 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