Developmental Therapeutics Program (DTP)

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href="/discovery_development/default.htm" class="discoveryDevelopment">Discovery & Development Services</a> <ul> <li><a href="/discovery_development/default.htm#services_from_dtp">Services Available Directly From DTP</a></li> <li><a href="/discovery_development/default.htm#services_through_next">Services Available Through NExT</a></li> <li><a href="/discovery_development/stepping_stones/default.htm">Stepping Stones</a></li> </ul> </li> <li><a href="/repositories/default.htm" class="repositories">Repositories</a> <ul> <li><a href="/repositories/dctdtumorrepository/default.htm">Division of Cancer Treatment and Diagnosis (DCTD) Tumor Repository</a></li> <li><a href="https://pdmr.cancer.gov" target="_blank">Repository of Patient-Derived Models</a></li> <li><a href="/organization/dscb/obtaining/default.htm">Repository of Chemical Agents — Small Molecules and Pure Natural Products</a></li> <li><a href="/organization/npb/introduction.htm">Repository of Natural Products</a></li> <li><a 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href="/organization/mpb/default.htm" class="mpb">Molecular Pharmacology Branch</a></li> <li><a href="/organization/btb/default.htm" class="btb">Biological Testing Branch</a></li> <li><a href="/organization/tpb/default.htm" class="tpb">Toxicology and Pharmacology Branch</a></li> <li><a href="/organization/dscb/default.htm" class="dscb">Drug Synthesis and Chemistry Branch</a></li> <li><a href="/organization/npb/default.htm" class="npb">Natural Products Branch</a></li> <li><a href="/organization/brb/default.htm" class="brb">Biological Resources Branch</a></li> <li><a href="/organization/prb/default.htm" class="prb">Pharmaceutical Resources Branch</a></li> <li><a href="/organization/itb/default.htm" class="itb">Information Technology Branch</a></li> <li><a href="/organization/iob/default.htm" class="itb">ImmunoOncology Branch</a></li> </ul> </li> <li><a href="https://next.cancer.gov/experimentalTherapeutics/form.htm" target="_blank">Consultation</a></li> <li><a href="/contact_us/default.htm" class="contactUs">Contact Us</a></li> </ul> </div> <style type="text/css"> #dtpHomeAccessHelpContent { padding: 0 0 20px 0; } #dtpHomeAccessHelpContent h1 { font-size: 1px; color: #FFF!important; margin-left: -2000px; } #dtpHomeAccessHelpContent p { font-size: 14px; line-height: 1.4em; } #dtpHomeAccessHelpContent h2 { font-size: 14px; line-height: 1.4em; font-weight: bold; padding: 14px 0; text-align: center;} #accessHelpImage img { max-width: 100%; } #programBox, #servicesBox { margin-top: 0!important; } @media screen and (max-width: 1036px) { #dtpHomeAccessHelpContent { padding: 0 15px 15px 15px; } } </style> <div id="bodycopy"> <div id="mainColumn"> <div id="dtpHomeAccessHelpContent"> <h1>Developmental Therapeutics Program</h1> <p>The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.</p> <h2>Are you a researcher in cancer drug discovery or development?</h2> <div id="accessHelpImage"><a href="/discovery_development/access_resources.htm"><img src="/images/redesign/access-help02.png" alt="Access Help Here: Advancing a Therapeutic Candidate to the Clinic, from the Developmental Therapeutics Program" /></a></div> </div> <div id="programBox" class="paElements"> <div class="homeboxWrapper"> <h2>DTP Branches and Offices</h2> <div class="homeProgramBox"> <div class="programAcronym"><a href="/organization/oad/default.htm">OAD</a></div> <div class="programText"><a href="/organization/oad/default.htm">Office of the Associate Director</a></div> </div> <div class="homeProgramBox"> <div class="programAcronym"><a href="/organization/ptgb/default.htm">PTGB</a></div> <div class="programText"><a href="/organization/ptgb/default.htm">Preclinical Therapeutics Grants Branch</a></div> </div> <div class="homeProgramBox"> <div class="programAcronym"><a href="/organization/mpb/default.htm">MPB</a></div> <div class="programText"><a href="/organization/mpb/default.htm">Molecular Pharmacology Branch</a></div> </div> <div class="homeProgramBox"> <div class="programAcronym"><a href="/organization/btb/default.htm">BTB</a></div> <div class="programText"><a href="/organization/btb/default.htm">Biological Testing Branch</a></div> </div> <div class="homeProgramBox"> <div class="programAcronym"><a href="/organization/tpb/default.htm">TPB</a></div> <div class="programText"><a href="/organization/tpb/default.htm">Toxicology and Pharmacology Branch</a></div> </div> <div class="homeProgramBox"> <div class="programAcronym"><a href="/organization/dscb/default.htm">DSCB</a></div> <div class="programText"><a href="/organization/dscb/default.htm">Drug Synthesis and Chemistry Branch</a></div> </div> <div class="homeProgramBox"> <div class="programAcronym"><a href="/organization/npb/default.htm">NPB</a></div> <div class="programText"><a href="/organization/npb/default.htm">Natural Products Branch</a></div> </div> <div class="homeProgramBox"> <div class="programAcronym"><a href="/organization/brb/default.htm">BRB</a></div> <div class="programText"><a href="/organization/brb/default.htm">Biological Resources Branch</a></div> </div> <div class="homeProgramBox"> <div class="programAcronym"><a href="/organization/prb/default.htm">PRB</a></div> <div class="programText"><a href="/organization/prb/default.htm">Pharmaceutical Resources Branch</a></div> </div> <div class="homeProgramBox"> <div class="programAcronym"><a href="/organization/itb/default.htm">ITB</a></div> <div class="programText"><a href="/organization/itb/default.htm">Information Technology Branch</a></div> </div> <div class="homeProgramBox"> <div class="programAcronym"><a href="/organization/iob/default.htm">IOB</a></div> <div class="programText"><a href="/organization/iob/default.htm">ImmunoOncology Branch</a></div> </div> </div> </div> <div id="servicesBox" class="paElements"> <div class="homeboxWrapper"> <h2>DTP services and resources:</h2> <h3><a href="/discovery_development/default.htm">DTP drug discovery and pre-clinic development services</a></h3> <p>Discovery services (NCI60 screening etc.) and pre-clinical support (pharmacology, toxicology and cGMP production etc.).</p> <h3><a href="/repositories/default.htm">DTP repositories</a></h3> <p>Synthetic compounds, natural products, biological samples and standards.</p> <h3><a href="/databases_tools/default.htm">DTP databases and searching/analysis tools</a></h3> <p>Bulk DTP chemical and biological data for searching and download, COMPARE analysis.</p> <h3><a href="/grants/default.htm">DTP grant programs</a></h3> <p>Grants for preclinical anti-cancer drug discovery and treatment, including small molecules, natural products and biological agents.</p> <h3><a href="https://next.cancer.gov/experimentalTherapeutics/form.htm" target="_blank">DCTD consultations</a></h3> <p>Advice on development of small molecules, biologics, and imaging products intended for cancer patients.</p> <h3><a href="/discovery_development/stepping_stones/default.htm">Stepping Stones</a></h3> <p>Access to discrete drug development studies for NCI/DCTD grantees.</p> </div> </div> </div> <div id="secondaryColumn"> <div id="messageFromDirector"> <h3>About the Associate Director</h3> <p><img src="/organization/oad/bios/branchchief_thumb.jpg" alt="Rosemarie Aurigemma, Ph.D." align="left" /> Rosemarie Aurigemma, Ph.D., has been a programmatic leader in drug development for over 20 years. Her tenure as the Deputy Associate Director of DTP resulted in the launch of the Stepping Stones preclinical development program as well as the initiation and expansion of biopharmaceutical manufacturing support for adoptive cell therapies. She served as Acting Associate Director of the DCTD Developmental Therapeutics Program beginning in January 2021 until her permanent appointment in September 2021. As Associate Director, she will be managing the oversight and coordination of the programmatic, financial, and administrative functions for DTP's ten active branches. <a href="/organization/oad/branch_chief.htm">More…</a></p> </div> <h3>DTP Hot Links</h3> <div class="hSidebarLink"><span><a href="https://dctd.cancer.gov/NewsEvents/20211203_NCI_Drug_Development_Workshop.htm" target="_blank">NCI Drug Development Workshop: How to Advance a Therapeutic Candidate from Bench to Bedside</a></span></div> <div class="hSidebarLink"><span><a href="/docs/2023 AACR_DTP_Presentation_Website.pdf" target="_blank">2023 AACR DTP Presentation</a></span></div> <div class="hSidebarLink"><span><a href="https://dtp.cancer.gov/compsub/" target="_blank">Compound Submission Application for NCI60 Screening</a></span></div> <div class="hSidebarLink"><span><a href="/organization/dscb/obtaining/default.htm">Request Vialed or Plated Compounds</a></span></div> <div class="hSidebarLink"><span><a href="https://dtp.cancer.gov/RequestCompounds/" target="_blank">Compound Request Form</a></span></div> <div class="hSidebarLink"><span><a href="https://dtp.cancer.gov/OrderAuth/" target="_blank">Authorize/View Compound Orders</a></span></div> <div class="hSidebarLink"><span><a href="/databases_tools/compare.htm">COMPARE Analysis</a></span></div> <div class="hSidebarLink"><span><a href="https://discover.nci.nih.gov/cellminer/">NCI-60 Analysis Tools (CellMiner)</a></span></div> <h3>Highlights</h3> <div class="hSidebarLink"><span><a href="/timeline/noflash/index.htm">DTP History</a></span></div> <div class="hSidebarLink"><span><a href="/discovery_development/approved_drugs.htm">Cancer Drugs Developed With DTP Involvement</a></span></div> <div class="hSidebarLink"><span><a href="http://next.cancer.gov" target="_blank">NExT</a></span></div> <h3>What’s New</h3> <div class="hSidebarLink"><span><a href="/databases_tools/roadmaps.htm">ROADMAPS Dataset</a></span></div> <div class="hSidebarLink"><span><a href="https://dtp.cancer.gov/ncialmanac/initializePage.do">NCI ALMANAC Study Results</a></span></div> <div class="hSidebarLink"><span><a href="/organization/dscb/obtaining/available_plates.htm">Plate of FDA-Approved Oncology Drugs</a></span></div> <div class="hSidebarLink"><span><a href="http://sarcoma.cancer.gov/sarcoma/documentation.xhtml" target="_blank">Sarcoma Project</a></span></div> <div class="hSidebarLink"><span><a href="https://sclccelllines.cancer.gov/sclc/" target="_blank">Small Cell Lung Cancer Screening Project</a></span></div> </div>  </div> </div> </div> <div id="footer"> <ul> <li><a href="/default.htm">DTP Home</a></li> <li><a href="/contact_us/default.htm">Contact DTP</a></li> <li><a href="/sitemap.htm">Site Map</a></li> <li><a href="https://www.cancer.gov/policies/accessibility" target="_blank">Accessibility</a></li> <li><a href="https://www.cancer.gov/policies/disclaimer" target="_blank">Disclaimer Policy</a></li> <li><a href="https://www.cancer.gov/policies/foia" target="_blank">FOIA</a></li> <li class="last"><a href="https://www.hhs.gov/vulnerability-disclosure-policy" target="_blank">HHS Vulnerability Disclosure</a></li> </ul> <ul id="agencyLinks"> <li><a href="http://www.hhs.gov/">U.S. Department of Health and Human Services</a></li> <li><a href="http://www.nih.gov/">National Institutes of Health</a></li> <li><a href="http://www.cancer.gov/">National Cancer Institute</a></li> <li class="last"><a href="http://www.usa.gov/">USA.gov</a></li> </ul> <div id="bottomTagline">NIH… Turning Discovery Into Health<sup>®</sup></div> </div> </div>  <script type='text/javascript'> (function(){var g=function(e,h,f,g){ this.get=function(a){for(var a=a+"=",c=document.cookie.split(";"),b=0,e=c.length;b<e;b++){for(var d=c[b];" "==d.charAt(0);)d=d.substring(1,d.length);if(0==d.indexOf(a))return d.substring(a.length,d.length)}return null}; this.set=function(a,c){var b="",b=new Date;b.setTime(b.getTime()+6048E5);b="; expires="+b.toGMTString();document.cookie=a+"="+c+b+"; path=/; "}; this.check=function(){var a=this.get(f);if(a)a=a.split(":");else if(100!=e)"v"==h&&(e=Math.random()>=e/100?0:100),a=[h,e,0],this.set(f,a.join(":"));else return!0;var c=a[1];if(100==c)return!0;switch(a[0]){case "v":return!1;case "r":return c=a[2]%Math.floor(100/c),a[2]++,this.set(f,a.join(":")),!c}return!0}; this.go=function(){if(this.check()){var a=document.createElement("script");a.type="text/javascript";a.src=g;document.body&&document.body.appendChild(a)}}; this.start=function(){var t=this;"complete"!==document.readyState?window.addEventListener?window.addEventListener("load",function(){t.go()},!1):window.attachEvent&&window.attachEvent("onload",function(){t.go()}):t.go()};}; try{(new g(100,"r","QSI_S_ZN_3jWKmtHCom1P33n","https://zn3jwkmthcom1p33n-nci.siteintercept.qualtrics.com/SIE/?Q_ZID=ZN_3jWKmtHCom1P33n")).start()}catch(i){}})(); </script><div id='ZN_3jWKmtHCom1P33n'></div>  </body> </html>

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Developmental Therapeutics Program (DTP)