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hydrogel beads</title> <meta name="description" content="Search results for: alginate hydrogel beads"> <meta name="keywords" content="alginate hydrogel beads"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="alginate hydrogel beads"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 316</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: alginate hydrogel beads</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">316</span> Effect of Alginate and Surfactant on Physical Properties of Oil Entrapped Alginate Bead Formulation of Curcumin</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Arpa%20Petchsomrit">Arpa Petchsomrit</a>, <a href="https://publications.waset.org/abstracts/search?q=Namfa%20Sermkaew"> Namfa Sermkaew</a>, <a href="https://publications.waset.org/abstracts/search?q=Ruedeekorn%20Wiwattanapatapee"> Ruedeekorn Wiwattanapatapee</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Oil entrapped floating alginate beads of curcumin were developed and characterized. Cremophor EL, Cremophor RH and Tween 80 were utilized to improve the solubility of the drug. The oil-loaded floating gel beads prepared by emulsion gelation method contained sodium alginate, mineral oil and surfactant. The drug content and % encapsulation declined as the ratio of surfactant was increased. The release of curcumin from 1% alginate beads was significantly more than for the 2% alginate beads. The drug released from the beads containing 25% of tween 80 was about 70% while a higher drug release was observed with the beads containing Cremophor EL or Cremohor RH (approximately 90%). The developed floating beads of curcumin powder with surfactant provided a superior drug release than those without surfactant. Floating beads based on oil entrapment containing the drug solubilized in surfactants is a new delivery system to enhance the dissolution of poorly soluble drugs. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=alginate" title="alginate">alginate</a>, <a href="https://publications.waset.org/abstracts/search?q=curcumin" title=" curcumin"> curcumin</a>, <a href="https://publications.waset.org/abstracts/search?q=floating%20drug%20delivery" title=" floating drug delivery"> floating drug delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=oil%20entrapped%20bead" title=" oil entrapped bead"> oil entrapped bead</a> </p> <a href="https://publications.waset.org/abstracts/3633/effect-of-alginate-and-surfactant-on-physical-properties-of-oil-entrapped-alginate-bead-formulation-of-curcumin" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/3633.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">385</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">315</span> Hydrogels Beads of Alginate/Seaweed Powder for Plants Nutrition</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Brenda%20O.%20Mazzola">Brenda O. Mazzola</a>, <a href="https://publications.waset.org/abstracts/search?q=Adriel%20Larsen"> Adriel Larsen</a>, <a href="https://publications.waset.org/abstracts/search?q=Romina%20P.%20Ollier"> Romina P. Ollier</a>, <a href="https://publications.waset.org/abstracts/search?q=Leandro%20N.%20Ludue%C3%B1a"> Leandro N. Ludueña</a>, <a href="https://publications.waset.org/abstracts/search?q=Vera%20A.%20Alvarez"> Vera A. Alvarez</a>, <a href="https://publications.waset.org/abstracts/search?q=Jimena%20S.%20Gonzalez"> Jimena S. Gonzalez</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Seaweed is a natural renewable resource with great potential that is not being used by the domestic industry. Here, it was used a kind of invasive algae U. Pinnatifida that causes serious ecological damage on the Argentinian coasts. Alginate is one of the most widely used materials for encapsulation, and has the advantage that is a natural polysaccharide derived from a marine plant. It can form thermally stable hydrogel in the presence of calcium cation. In addition, the hydrogel can be easily produced into particulate form by using simple and gentle method. The aim of this work was to obtain and to characterize novel compounds (alginate/seaweed powder) for the soil nutrition. Alginate water solutions were prepared by concentrations of 20, 30, 40 and 50 g/L, in those solutions 10g/L of seaweed powder was added. Then the dispersions were transferred from a beaker to the atomizer by a peristaltic pump (with 0.05 to 0.1 L/h flow). A tank was filled with 1 L of calcium chloride solution (4 g/L), and the solution was agitated with a magnetic stirrer. The beads were analyzed by means TGA, FTIR and swelling determinations. In addition, the improvements in the soil were qualitative measured. It was obtained beads with different diameters depend on the initial concentration and the flow used. A better dispersions of seaweed and optimal diameter for the plant nutrition applications were obtained for 40g/L concentration and 0.1 L/h flow. The beads show thermal stability and high swelling degree. It can be successfully obtained alginate beads with seaweed powder with a novelty application as plant nutrient. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biodegradable" title="biodegradable">biodegradable</a>, <a href="https://publications.waset.org/abstracts/search?q=characterization" title=" characterization"> characterization</a>, <a href="https://publications.waset.org/abstracts/search?q=hydrogel" title=" hydrogel"> hydrogel</a>, <a href="https://publications.waset.org/abstracts/search?q=plant%20nutrition" title=" plant nutrition"> plant nutrition</a>, <a href="https://publications.waset.org/abstracts/search?q=seaweed" title=" seaweed"> seaweed</a> </p> <a href="https://publications.waset.org/abstracts/46769/hydrogels-beads-of-alginateseaweed-powder-for-plants-nutrition" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/46769.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">280</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">314</span> Preparation of Composite Alginate/Perlite Beads for Pb (II) Removal in Aqueous Solution </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hasan%20T%C3%BCre">Hasan Türe</a>, <a href="https://publications.waset.org/abstracts/search?q=Kader%20Terzioglu"> Kader Terzioglu</a>, <a href="https://publications.waset.org/abstracts/search?q=Evren%20Tunca"> Evren Tunca</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Contamination of aqueous environment by heavy metal ions is a serious and complex problem, owing to their hazards to human being and ecological systems. The treatment methods utilized for removing metal ions from aqueous solution include membrane separation, ion exchange and chemical precipitation. However, these methods are limited by high operational cost. Recently, biobased beads are considered as promising biosorbent to remove heavy metal ions from water. The aim of present study was to characterize the alginate/perlite composite beads and to investigate the adsorption performance of obtained beads for removing Pb (II) from aqueous solution. Alginate beads were synthesized by ionic gelation methods and different amount of perlite (aljinate:perlite=1, 2, 3, 4, 5 wt./wt.) was incorporated into alginate beads. Samples were characterized by means of X-ray diffraction (XRD), thermogravimetric analysis (TGA), scanning electron microscopy (SEM). The effects of perlite level, the initial concentration of Pb (II), initial pH value of Pb(II) solution and effect of contact time on the adsorption capacity of beads were investigated by using batch method. XRD analysis indicated that perlite includes silicon or silicon and aluminum bearing crystalline phase. The diffraction pattern of perlite containing beads is similar to that of that perlite powder with reduced intensity. SEM analysis revealed that perlite was embedded into alginate polymer and SEM-EDX (Energy-Dispersive X-ray) showed that composite beads (aljinate:perlite=1) composed of C (41.93 wt.%,), O (43.64 wt.%), Na (10.20 wt.%), Al (0.74 wt.%), Si (2.72 wt.%) ve K (0.77 wt.%). According to TGA analysis, incorporation of perlite into beads significantly improved the thermal stability of the samples. Batch experiment indicated that optimum pH value for Pb (II) adsorption was found at pH=7 with 1 hour contact time. It was also found that the adsorption capacity of beads decreased with increases in perlite concentration. The results implied that alginate/perlite composite beads could be used as promising adsorbents for the removal of Pb (II) from wastewater. Acknowledgement: This study was supported by TUBITAK (Project No: 214Z146). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=alginate" title="alginate">alginate</a>, <a href="https://publications.waset.org/abstracts/search?q=adsorption" title=" adsorption"> adsorption</a>, <a href="https://publications.waset.org/abstracts/search?q=beads" title=" beads"> beads</a>, <a href="https://publications.waset.org/abstracts/search?q=perlite" title=" perlite"> perlite</a> </p> <a href="https://publications.waset.org/abstracts/46495/preparation-of-composite-alginateperlite-beads-for-pb-ii-removal-in-aqueous-solution" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/46495.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">289</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">313</span> [Keynote Talk]: Uptake of Co(II) Ions from Aqueous Solutions by Low-Cost Biopolymers and Their Hybrid</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kateryna%20Zhdanova">Kateryna Zhdanova</a>, <a href="https://publications.waset.org/abstracts/search?q=Evelyn%20Szeinbaum"> Evelyn Szeinbaum</a>, <a href="https://publications.waset.org/abstracts/search?q=Michelle%20Lo"> Michelle Lo</a>, <a href="https://publications.waset.org/abstracts/search?q=Yeonjae%20Jo"> Yeonjae Jo</a>, <a href="https://publications.waset.org/abstracts/search?q=Abel%20E.%20Navarro"> Abel E. Navarro</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Alginate hydrogel beads (AB), spent peppermint leaf (PM), and a hybrid adsorbent of these two materials (ABPM) were studied as potential biosorbents of Cobalt (II) ions from aqueous solutions. Cobalt ion is a commonly underestimated pollutant that is responsible for several health problems. Discontinuous batch experiments were conducted at room temperature to evaluate the effect of solution acidity, mass of adsorbent on the adsorption of Co(II) ions. The interfering effect of salinity, the presence of surfactants, an organic dye, and Pb(II) ions were also studied to resemble the application of these adsorbents in real wastewater. Equilibrium results indicate that Co(II) uptake is maximized at pH values higher than 5, with adsorbent doses of 200 mg, 200 mg, and 120 mg for AB, PM, and ABPM, respectively. Co(II) adsorption followed the trend AB > ABPM > PM with Adsorption percentages of 77%, 71% and 64%, respectively. Salts had a strong negative effect on the adsorption due to the increase of the ionic strength and the competition for adsorption sites. The presence of Pb(II) ions, surfactant, and dye BY57 had a slightly negative effect on the adsorption, apparently due to their interaction with different adsorption sites that do not interfere with the removal of Co(II). A polar-electrostatic adsorption mechanism is proposed based on the experimental results. Scanning electron microscopy indicates that adsorbent has appropriate morphological and textural properties, and also that ABPM encapsulated most of the PM inside of the hydrogel beads. These experimental results revealed that AB, PM, and ABPM are promising adsorbents for the elimination of Co(II) ions from aqueous solutions under different experimental conditions. These biopolymers are proposed as eco-friendly alternatives for the removal of heavy metal ions at lower costs than the conventional techniques. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adsorption" title="adsorption">adsorption</a>, <a href="https://publications.waset.org/abstracts/search?q=Co%28II%29%20ions" title=" Co(II) ions"> Co(II) ions</a>, <a href="https://publications.waset.org/abstracts/search?q=alginate%20hydrogel%20beads" title=" alginate hydrogel beads"> alginate hydrogel beads</a>, <a href="https://publications.waset.org/abstracts/search?q=spent%20peppermint%20leaf" title=" spent peppermint leaf"> spent peppermint leaf</a>, <a href="https://publications.waset.org/abstracts/search?q=pH" title=" pH"> pH</a> </p> <a href="https://publications.waset.org/abstracts/113482/keynote-talk-uptake-of-coii-ions-from-aqueous-solutions-by-low-cost-biopolymers-and-their-hybrid" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/113482.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">128</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">312</span> Pectin Degrading Enzyme: Entrapment of Pectinase Using Different Synthetic and Non-Synthetic Polymers for Continuous Degradation of Pectin Polymer </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Haneef%20Ur%20Rehman">Haneef Ur Rehman</a>, <a href="https://publications.waset.org/abstracts/search?q=Afsheen%20Aman"> Afsheen Aman</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdul%20Hameed%20Baloch"> Abdul Hameed Baloch</a>, <a href="https://publications.waset.org/abstracts/search?q=Shah%20Ali%20Ul%20Qader"> Shah Ali Ul Qader</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Pectinase is a heterogeneous group of enzymes that catalyze the hydrolysis of pectin substances and widely has been used in food and textile industries. In current study, pectinase from B. licheniformis KIBGE-IB21 was immobilized within different polymers (calcium alginate beads, polyacrylamide gel and agar-agar matrix) to enhance its catalytic properties. Polyacrylamide gel was found to be most promising one and gave maximum (89%) immobilization yield. While less immobilization yield was observed in case of calcium alginate beads that only retained 46 % activity. The reaction time for maximum pectinolytic activity was increased from 5.0 to 10 minutes after immobilization. The temperature of pectinase for maximum enzyme activity was increased from 45 °C to 50 °C and 55 °C when it was immobilized within agar-agar and calcium alginate beads, respectively. The optimum pH of pectinase didn’t alter when it was immobilized within polyacrylamide gel and calcium alginate beads, but in case of agar-agar it was changed from pH 10 to pH 9.0. Thermal stability of pectinase was improved after immobilization and immobilized pectinase showed higher toleration against different temperatures as compared to free enzyme. It can be concluded that the entrapment is a simple, single step and promising procedure to immobilized pectinase within different synthetic and non-synthetic polymers and enhanced its catalytic properties. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pectinase" title="pectinase">pectinase</a>, <a href="https://publications.waset.org/abstracts/search?q=characterization%20immobilization" title=" characterization immobilization"> characterization immobilization</a>, <a href="https://publications.waset.org/abstracts/search?q=polyacrylamide" title=" polyacrylamide"> polyacrylamide</a>, <a href="https://publications.waset.org/abstracts/search?q=agar-agar" title=" agar-agar"> agar-agar</a>, <a href="https://publications.waset.org/abstracts/search?q=calcium%20alginate%20beads" title=" calcium alginate beads"> calcium alginate beads</a> </p> <a href="https://publications.waset.org/abstracts/21905/pectin-degrading-enzyme-entrapment-of-pectinase-using-different-synthetic-and-non-synthetic-polymers-for-continuous-degradation-of-pectin-polymer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21905.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">606</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">311</span> Magnetic Biomaterials for Removing Organic Pollutants from Wastewater</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=L.%20Obeid">L. Obeid</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Bee"> A. Bee</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20Talbot"> D. Talbot</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Abramson"> S. Abramson</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Welschbillig"> M. Welschbillig</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The adsorption process is one of the most efficient methods to remove pollutants from wastewater provided that suitable adsorbents are used. In order to produce environmentally safe adsorbents, natural polymers have received increasing attention in recent years. Thus, alginate and chitosane are extensively used as inexpensive, non-toxic and efficient biosorbents. Alginate is an anionic polysaccharide extracted from brown seaweeds. Chitosan is an amino-polysaccharide; this cationic polymer is obtained by deacetylation of chitin the major constituent of crustaceans. Furthermore, it has been shown that the encapsulation of magnetic materials in alginate and chitosan beads facilitates their recovery from wastewater after the adsorption step, by the use of an external magnetic field gradient, obtained with a magnet or an electromagnet. In the present work, we have studied the adsorption affinity of magnetic alginate beads and magnetic chitosan beads (called magsorbents) for methyl orange (MO) (an anionic dye), methylene blue (MB) (a cationic dye) and p-nitrophenol (PNP) (a hydrophobic pollutant). The effect of different parameters (pH solution, contact time, pollutant initial concentration…) on the adsorption of pollutant on the magnetic beads was investigated. The adsorption of anionic and cationic pollutants is mainly due to electrostatic interactions. Consequently methyl orange is highly adsorbed by chitosan beads in acidic medium and methylene blue by alginate beads in basic medium. In the case of a hydrophobic pollutant, which is weakly adsorbed, we have shown that the adsorption is enhanced by adding a surfactant. Cetylpyridinium chloride (CPC), a cationic surfactant, was used to increase the adsorption of PNP by magnetic alginate beads. Adsorption of CPC by alginate beads occurs through two mechanisms: (i) electrostatic attractions between cationic head groups of CPC and negative carboxylate functions of alginate; (ii) interaction between the hydrocarbon chains of CPC. The hydrophobic pollutant is adsolubilized within the surface aggregated structures of surfactant. Figure c shows that PNP can reach up to 95% of adsorption in presence of CPC. At highest CPC concentrations, desorption occurs due to the formation of micelles in the solution. Our magsorbents appear to efficiently remove ionic and hydrophobic pollutants and we hope that this fundamental research will be helpful for the future development of magnetically assisted processes in water treatment plants. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adsorption" title="adsorption">adsorption</a>, <a href="https://publications.waset.org/abstracts/search?q=alginate" title=" alginate"> alginate</a>, <a href="https://publications.waset.org/abstracts/search?q=chitosan" title=" chitosan"> chitosan</a>, <a href="https://publications.waset.org/abstracts/search?q=magsorbent" title=" magsorbent"> magsorbent</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic" title=" magnetic"> magnetic</a>, <a href="https://publications.waset.org/abstracts/search?q=organic%20pollutant" title=" organic pollutant"> organic pollutant</a> </p> <a href="https://publications.waset.org/abstracts/2514/magnetic-biomaterials-for-removing-organic-pollutants-from-wastewater" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/2514.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">257</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">310</span> Improving Alginate Bioink by Recombinant Spider-Silk Biopolymer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dean%20Robinson">Dean Robinson</a>, <a href="https://publications.waset.org/abstracts/search?q=Miriam%20Gublebank"> Miriam Gublebank</a>, <a href="https://publications.waset.org/abstracts/search?q=Ella%20Sklan"> Ella Sklan</a>, <a href="https://publications.waset.org/abstracts/search?q=Tali%20Tavor%20Re%27em"> Tali Tavor Re'em</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Alginate, a natural linear polysaccharide polymer extracted from brown seaweed, is extensively applied due to its biocompatibility, all- aqueous ease of handling, and relatively low costs. Alginate easily forms a hydrogel when crosslinked with a divalent ion, such as calcium. However, Alginate hydrogel holds low mechanical properties and is cell-inert. To overcome these drawbacks and to improve alginate as a bio-ink for bioprinting, we produced a new alginate matrix combined with spider silk, one of the most resilient, elastic, strong materials known to men. Recombinant spider silk biopolymer has a sponge-like structure and is known to be biocompatible and non-immunogenic. Our results indicated that combining synthetic spider-silk into bio-printed cell-seeded alginate hydrogels resulted in improved properties compared to alginate: improved mechanical properties of the matrix, achieving a tunable gel viscosity and high printability, alongside prolonged and higher cell viability in culture, probably due to the improved cell-matrix interactions. The new bio-ink was then used for bilayer bioprinting of epithelial and stromal endometrial cells. Such a co-culture model will be used for the formation of the complex endometrial tissue for studying the embryo implantation process. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cell%20culture" title="cell culture">cell culture</a>, <a href="https://publications.waset.org/abstracts/search?q=tissue%20engineering" title=" tissue engineering"> tissue engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=spider%20silk" title=" spider silk"> spider silk</a>, <a href="https://publications.waset.org/abstracts/search?q=alginate" title=" alginate"> alginate</a>, <a href="https://publications.waset.org/abstracts/search?q=bioprinting" title=" bioprinting"> bioprinting</a> </p> <a href="https://publications.waset.org/abstracts/148116/improving-alginate-bioink-by-recombinant-spider-silk-biopolymer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/148116.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">197</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">309</span> Novel IPN Hydrogel Beads as pH Sensitive Drug Delivery System for an Anti-Ulcer Drug</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Vishal%20Kumar%20Gupta">Vishal Kumar Gupta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: This study has been undertaken to develop novel pH sensitive interpenetrating network hydrogel beads. Methods: The pH sensitive PAAM-g-Guar gum copolymer was synthesized by free radical polymerization followed by alkaline hydrolysis. Beads of guar gum-grafted-polyacrylamide and sodium Carboxy methyl cellulose (Na CMC) loaded with Pantoprazole sodium were prepared and evaluated for pH sensitivity, swelling properties, drug entrapment efficiency and in vitro drug release characteristics. Seven formulations were prepared for the drug with varying polymer and cross linker concentrations. Results: The grafting and alkaline hydrolysis reactions were confirmed by FT-IR spectroscopy. Differential scanning calorimetry was carried out to know the compatibility of encapsulated drug with the polymers. Scanning electron microscopic study revealed that the IPN beads were spherical. The entrapment efficiency was found to be in the range of 85-92%. Particle size analysis was carried out by optical microscopy. As the pH of the medium was changed from 1.2 to 7.4, a considerable increase in swelling was observed for all beads. Increase in the copolymer concentration showed sustained the drug release up to 12 hrs. Drug release from the beads followed super case II transport mechanism. Conclusion: It was concluded that guar gum-acrylamide beads, cross-linked with aluminum chloride offer an opportunity for controlled drug release of pantoprazole sodium. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=IPN" title="IPN">IPN</a>, <a href="https://publications.waset.org/abstracts/search?q=hydrogels" title=" hydrogels"> hydrogels</a>, <a href="https://publications.waset.org/abstracts/search?q=DSC" title=" DSC"> DSC</a>, <a href="https://publications.waset.org/abstracts/search?q=SEM" title=" SEM"> SEM</a> </p> <a href="https://publications.waset.org/abstracts/8471/novel-ipn-hydrogel-beads-as-ph-sensitive-drug-delivery-system-for-an-anti-ulcer-drug" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/8471.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">269</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">308</span> Optimization of Mechanical Properties of Alginate Hydrogel for 3D Bio-Printing Self-Standing Scaffold Architecture for Tissue Engineering Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ibtisam%20A.%20Abbas%20Al-Darkazly"> Ibtisam A. Abbas Al-Darkazly</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, the mechanical properties of alginate hydrogel material for self-standing 3D scaffold architecture with proper shape fidelity are investigated. In-lab built 3D bio-printer extrusion-based technology is utilized to fabricate 3D alginate scaffold constructs. The pressure, needle speed and stage speed are varied using a computer-controlled system. The experimental result indicates that the concentration of alginate solution, calcium chloride (CaCl<sub>2</sub>) cross-linking concentration and cross-linking ratios lead to the formation of alginate hydrogel with various gelation states. Besides, the gelling conditions, such as cross-linking reaction time and temperature also have a significant effect on the mechanical properties of alginate hydrogel. Various experimental tests such as the material gelation, the material spreading and the printability test for filament collapse as well as the swelling test were conducted to evaluate the fabricated 3D scaffold constructs. The result indicates that the fabricated 3D scaffold from composition of 3.5% wt alginate solution, that is prepared in DI water and 1% wt CaCl<sub>2</sub> solution with cross-linking ratios of 7:3 show good printability and sustain good shape fidelity for more than 20 days, compared to alginate hydrogel that is prepared in a phosphate buffered saline (PBS). The fabricated self-standing 3D scaffold constructs measured 30 mm × 30 mm and consisted of 4 layers (n = 4) show good pore geometry and clear grid structure after printing. In addition, the percentage change of swelling degree exhibits high swelling capability with respect to time. The swelling test shows that the geometry of 3D alginate-scaffold construct and of the macro-pore are rarely changed, which indicates the capability of holding the shape fidelity during the incubation period. This study demonstrated that the mechanical and physical properties of alginate hydrogel could be tuned for a 3D bio-printing extrusion-based system to fabricate self-standing 3D scaffold soft structures. This 3D bioengineered scaffold provides a natural microenvironment present in the extracellular matrix of the tissue, which could be seeded with the biological cells to generate the desired 3D live tissue model for <em>in vitro</em> and <em>in vivo</em> tissue engineering applications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biomaterial" title="biomaterial">biomaterial</a>, <a href="https://publications.waset.org/abstracts/search?q=calcium%20chloride" title=" calcium chloride"> calcium chloride</a>, <a href="https://publications.waset.org/abstracts/search?q=3D%20bio-printing" title=" 3D bio-printing"> 3D bio-printing</a>, <a href="https://publications.waset.org/abstracts/search?q=extrusion" title=" extrusion"> extrusion</a>, <a href="https://publications.waset.org/abstracts/search?q=scaffold" title=" scaffold"> scaffold</a>, <a href="https://publications.waset.org/abstracts/search?q=sodium%20alginate" title=" sodium alginate"> sodium alginate</a>, <a href="https://publications.waset.org/abstracts/search?q=tissue%20engineering" title=" tissue engineering"> tissue engineering</a> </p> <a href="https://publications.waset.org/abstracts/132067/optimization-of-mechanical-properties-of-alginate-hydrogel-for-3d-bio-printing-self-standing-scaffold-architecture-for-tissue-engineering-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/132067.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">111</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">307</span> Adsorptive Removal of Cd(II) Ions from Aqueous Systems by Wood Ash-Alginate Composite Beads</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tichaona%20Nharingo">Tichaona Nharingo</a>, <a href="https://publications.waset.org/abstracts/search?q=Hope%20Tauya"> Hope Tauya</a>, <a href="https://publications.waset.org/abstracts/search?q=Mambo%20Moyo"> Mambo Moyo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Wood ash has been demonstrated to have favourable adsorption capacity for heavy metal ions but suffers the application problem of difficult to separate/isolate from the batch adsorption systems. Fabrication of wood ash beads using multifunctional group and non-toxic carbohydrate, alginate, may improve the applicability of wood ash in environmental pollutant remediation. In this work, alginate-wood ash beads (AWAB) were fabricated and applied to the removal of cadmium ions from aqueous systems. The beads were characterized by FTIR, TGA/DSC, SEM-EDX and their pHZPC before and after the adsorption of Cd(II) ions. Important adsorption parameters i.e. pH, AWAB dosage, contact time and ionic strength were optimized and the effect of initial concentration of Cd(II) ions to the adsorption process was established. Adsorption kinetics, adsorption isotherms, adsorption mechanism and application of AWAB to real water samples spiked with Cd(II) ions were ascertained. The composite adsorbent was characterized by a heterogeneous macro pore surface comprising of metal oxides, multiple hydroxyl groups and carbonyl groups that were involved in electrostatic interaction and Lewis acid-base interactions with the Cd(II) ions. The pseudo second order and the Freundlich isotherm models best fitted the adsorption kinetics and isotherm data respectively suggesting chemical sorption process and surface heterogeneity. The presence of Pb(II) ions inhibited the adsorption of Cd(II) ions (reduced by 40 %) attributed to the competition for the adsorption sites. The Cd(II) loaded beads could be regenerated using 0.1 M HCl and could be applied to four sorption-desorption cycles without significant loss in its initial adsorption capacity. The high maximum adsorption capacity, stability, selectivity and reusability of AWAB make the adsorbent ideal for application in the removal of Cd(II) ions from real water samples. Column type adsorption experiments need to be explored to establish the potential of the adsorbent in removing Cd(II) ions using continuous flow systems. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adsorption" title="adsorption">adsorption</a>, <a href="https://publications.waset.org/abstracts/search?q=Cd%28II%29%20ions" title=" Cd(II) ions"> Cd(II) ions</a>, <a href="https://publications.waset.org/abstracts/search?q=regeneration" title=" regeneration"> regeneration</a>, <a href="https://publications.waset.org/abstracts/search?q=wastewater" title=" wastewater"> wastewater</a>, <a href="https://publications.waset.org/abstracts/search?q=wood%20ash-alginate%20beads" title=" wood ash-alginate beads"> wood ash-alginate beads</a> </p> <a href="https://publications.waset.org/abstracts/52416/adsorptive-removal-of-cdii-ions-from-aqueous-systems-by-wood-ash-alginate-composite-beads" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/52416.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">245</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">306</span> Spectrophotometric Evaluation of Custom Microalgae-Based Bioink Formulations for Optimized Green Bioprinting</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Olubusuyi%20Ayowole">Olubusuyi Ayowole</a>, <a href="https://publications.waset.org/abstracts/search?q=Bashir%20Khoda"> Bashir Khoda</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Green bioprinting, from the context of merging 3D bioprinting with microalgae cell organization, holds promise for industrial-scale optimization. This study employs spectrophotometric analysis to explore post-bioprinting cell growth density variation within hybrid hydrogel biomaterial scaffolds. Three hydrogel biomaterials—Alginic acid sodium salt (ALGINATE), Nanofibrillated Cellulose (NFC) – TEMPO, and CarboxyMethyl Cellulose (CMC)—are chosen for their scaffolding capabilities. Bioink development and analysis of their impact on cell proliferation and morphology are conducted. Chlorella microalgae cell growth within hydrogel compositions is probed using absorbance measurements, with additional assessment of shear thinning properties. Notably, NFC exhibits reduced shear thinning compared to CMC. Results reveal that while mono-hydrogel substrates with pronounced adhesion inhibit Chlorella cell proliferation, Alginate fosters increased cell concentration alongside a slight viscosity rise. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=green%20bioprinting" title="green bioprinting">green bioprinting</a>, <a href="https://publications.waset.org/abstracts/search?q=3d%20bioprinting" title=" 3d bioprinting"> 3d bioprinting</a>, <a href="https://publications.waset.org/abstracts/search?q=microalgae%20cell" title=" microalgae cell"> microalgae cell</a>, <a href="https://publications.waset.org/abstracts/search?q=hybrid%20hydrogel%20scaffolds" title=" hybrid hydrogel scaffolds"> hybrid hydrogel scaffolds</a>, <a href="https://publications.waset.org/abstracts/search?q=spectrophotometric%20analysis" title=" spectrophotometric analysis"> spectrophotometric analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=bioink%20development" title=" bioink development"> bioink development</a>, <a href="https://publications.waset.org/abstracts/search?q=shear%20thinning%20properties" title=" shear thinning properties"> shear thinning properties</a> </p> <a href="https://publications.waset.org/abstracts/188298/spectrophotometric-evaluation-of-custom-microalgae-based-bioink-formulations-for-optimized-green-bioprinting" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/188298.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">29</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">305</span> Adsorption of Reactive Dye Using Entrapped nZVI</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=P.%20Gomathi%20Priya">P. Gomathi Priya</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20E.%20Thenmozhi"> M. E. Thenmozhi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Iron nanoparticles were used to cleanup effluents. This paper involves synthesis of iron nanoparticles chemically by sodium borohydride reduction of ammonium ferrous sulfate solution (FAS). Iron oxide nanoparticles have lesser efficiency of adsorption than Zero Valent Iron nanoparticles (nZVI). Glucosamine acts as a stabilizing agent and chelating agent to prevent Iron nanoparticles from oxidation. nZVI particles were characterized using Scanning Electron Microscopy (SEM). Thus, the synthesized nZVI was subjected to entrapment in biopolymer, viz. barium (Ba)-alginate beads. The beads were characterized using SEM. Batch dye degradation studies were conducted using Reactive black Water soluble Nontoxic Natural substances (WNN) dye which is one of the most hazardous dyes used in textile industries. Effect of contact time, effect of pH, initial dye concentration, adsorbent dosage, isotherm and kinetic studies were carried out. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ammonium%20ferrous%20sulfate%20solution" title="ammonium ferrous sulfate solution">ammonium ferrous sulfate solution</a>, <a href="https://publications.waset.org/abstracts/search?q=barium" title=" barium"> barium</a>, <a href="https://publications.waset.org/abstracts/search?q=alginate%20beads" title=" alginate beads"> alginate beads</a>, <a href="https://publications.waset.org/abstracts/search?q=reactive%20black%20WNN%20dye" title=" reactive black WNN dye"> reactive black WNN dye</a>, <a href="https://publications.waset.org/abstracts/search?q=zero%20valent%20iron%20nanoparticles" title=" zero valent iron nanoparticles"> zero valent iron nanoparticles</a> </p> <a href="https://publications.waset.org/abstracts/85605/adsorption-of-reactive-dye-using-entrapped-nzvi" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/85605.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">331</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">304</span> Development of a Myocardial Patch with 3D Hydrogel Electrical Stimulation System</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yung-Gi%20Chen">Yung-Gi Chen</a>, <a href="https://publications.waset.org/abstracts/search?q=Pei-Leun%20Kang"> Pei-Leun Kang</a>, <a href="https://publications.waset.org/abstracts/search?q=Yu-Hsin%20Lin"> Yu-Hsin Lin</a>, <a href="https://publications.waset.org/abstracts/search?q=Shwu-Jen%20Chang"> Shwu-Jen Chang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Myocardial tissue has limited self-repair ability due to its loss of differentiation characteristic for most mature cardiomyocytes. Therefore, the effective use of stem cell technology in regenerative medicine is an important development to alleviate the current difficulties in cardiac disease treatment. The main purpose of this project was to develop a 3-D hydrogel electrical stimulating system for promoting the differentiation of stem cells into myocardial cells, and the patch will be used to repair damaged myocardial tissue. This project was focused on the preparation of the electrical stimulation system with carbon/CaCl₂ electrodes covered with carbon nanotube-hydrogel. In this study, we utilized screen imprinting techniques and used Poly(lactic-co-glycolic acid)(PLGA) membranes as printing substrates to fabricate a carbon/CaCl₂ interdigitated electrode that covered with alginate/carbon nanotube hydrogels. The single-walled carbon nanotube was added in the hydrogel to enhance the mechanical strength and conductivity of hydrogel. In this study, we used PLGA (85:15) as electrode preparing substrate. The CaCl₂/ EtOH solution (80% w/v) was mixed into carbon paste to prepare various concentration calcium-containing carbon paste (2.5%, 5%, 7.5%, 10% v/v). Different concentrations of alginate (1%, 1.5%, 2% v/v) and SWCNT(Diameter < 2nm, length between 5-15μm) (1, 1.5, 3 mg/ml) are gently immobilized on the electrode by cross-linking with calcium chloride. The three-dimensional hydrogel electrode was tested for its redox efficiency by cyclic voltammetry to determine the optimal parameters for the hydrogel electrode preparation. From the result of the final electrodes, it indicated that the electrode was not easy to maintain the pattern of the interdigitated electrode when the concentration of calcium of chloride was more than 10%. According to the gel rate test and cyclic voltammetry experiment results showed the SWCNT could increase the electron conduction of hydrogel electrodes significantly. So far the 3D electrode system has been completed, 2% alginate mixed with 3mg SWCNT is the optimal condition to construct the most complete structure for the hydrogel preparation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=myocardial%20tissue%20engineering" title="myocardial tissue engineering">myocardial tissue engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=screen%20printing%20technology" title=" screen printing technology"> screen printing technology</a>, <a href="https://publications.waset.org/abstracts/search?q=poly%20%28lactic-co-glycolic%20acid%29" title=" poly (lactic-co-glycolic acid)"> poly (lactic-co-glycolic acid)</a>, <a href="https://publications.waset.org/abstracts/search?q=alginate" title=" alginate"> alginate</a>, <a href="https://publications.waset.org/abstracts/search?q=single%20walled%20carbon%20nanotube" title=" single walled carbon nanotube"> single walled carbon nanotube</a> </p> <a href="https://publications.waset.org/abstracts/98452/development-of-a-myocardial-patch-with-3d-hydrogel-electrical-stimulation-system" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/98452.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">112</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">303</span> Controlled Release of Glucosamine from Pluronic-Based Hydrogels for the Treatment of Osteoarthritis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Papon%20Thamvasupong">Papon Thamvasupong</a>, <a href="https://publications.waset.org/abstracts/search?q=Kwanchanok%20Viravaidya-Pasuwat"> Kwanchanok Viravaidya-Pasuwat</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Osteoarthritis affects a lot of people worldwide. Local injection of glucosamine is one of the alternative treatment methods to replenish the natural lubrication of cartilage. However, multiple injections can potentially lead to possible bacterial infection. Therefore, a drug delivery system is desired to reduce the frequencies of injections. A hydrogel is one of the delivery systems that can control the release of drugs. Thermo-reversible hydrogels can be beneficial to the drug delivery system especially in the local injection route because this formulation can change from liquid to gel after getting into human body. Once the gel is in the body, it will slowly release the drug in a controlled manner. In this study, various formulations of Pluronic-based hydrogels were synthesized for the controlled release of glucosamine. One of the challenges of the Pluronic controlled release system is its fast dissolution rate. To overcome this problem, alginate and calcium sulfate (CaSO<sub>4</sub>) were added to the polymer solution. The characteristics of the hydrogels were investigated including the gelation temperature, gelation time, hydrogel dissolution and glucosamine release mechanism. Finally, a mathematical model of glucosamine release from Pluronic-alginate-hyaluronic acid hydrogel was developed. Our results have shown that crosslinking Pluronic gel with alginate did not significantly extend the dissolution rate of the gel. Moreover, the gel dissolution profiles and the glucosamine release mechanisms were best described using the zeroth-order kinetic model, indicating that the release of glucosamine was primarily governed by the gel dissolution. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=controlled%20release" title="controlled release">controlled release</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20delivery%20system" title=" drug delivery system"> drug delivery system</a>, <a href="https://publications.waset.org/abstracts/search?q=glucosamine" title=" glucosamine"> glucosamine</a>, <a href="https://publications.waset.org/abstracts/search?q=pluronic" title=" pluronic"> pluronic</a>, <a href="https://publications.waset.org/abstracts/search?q=thermoreversible%20hydrogel" title=" thermoreversible hydrogel"> thermoreversible hydrogel</a> </p> <a href="https://publications.waset.org/abstracts/51314/controlled-release-of-glucosamine-from-pluronic-based-hydrogels-for-the-treatment-of-osteoarthritis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/51314.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">270</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">302</span> Formulation and in Vitro Characterization of Bioactives Loaded Polymeric Nanoparticle Incorporated into Multiphase Hydrogel System for the Treatment of Infected Burn Wound</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rajni%20Kant%20Panik">Rajni Kant Panik</a>, <a href="https://publications.waset.org/abstracts/search?q=Deependra%20Singh"> Deependra Singh</a>, <a href="https://publications.waset.org/abstracts/search?q=Manju%20Singh"> Manju Singh </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Despite significant advances in the treatment of severe burn injury, infection and sepsis persist as frequent causes of morbidity and mortality for burn victims due to extensive compromise of the skin and contiguous tissue that serve as a protective barrier against microbial invasion. In the setting of a burn wound infection, Staphylococcus aureus is the most commonly isolated pathogens from bloodstream infections in burn care hospitals. We aimed to develop a biocompatible system of Poly vinyl alcohol (PVA)-sodium alginate hydrogel carrying multiple drugs- catalase and mupirocin in controlled manner for effective and complete burn wound healing. PLGA nanoparticles of Catalase and mupirocin were prepared by homogenization method and optimized system was incorporated in PVA-sodium alginate slurry. PVA-sodium alginate hydrogels were prepared by freeze thaw method. The prepared dispersion was casted into films to prepare multiphase hydrogel system and characterized by in vitro and in vivo studies. The study clearly showed the beneficial effect of antioxidant enzyme and antibiotic in the treatment of infected burn wound, as evidenced by the reduced incidence of wound infection and the shortening of healing time. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=burn%20wound" title="burn wound">burn wound</a>, <a href="https://publications.waset.org/abstracts/search?q=catalase" title=" catalase"> catalase</a>, <a href="https://publications.waset.org/abstracts/search?q=mupirocin" title=" mupirocin"> mupirocin</a>, <a href="https://publications.waset.org/abstracts/search?q=wound%20healing" title=" wound healing"> wound healing</a> </p> <a href="https://publications.waset.org/abstracts/30091/formulation-and-in-vitro-characterization-of-bioactives-loaded-polymeric-nanoparticle-incorporated-into-multiphase-hydrogel-system-for-the-treatment-of-infected-burn-wound" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30091.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">503</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">301</span> The Effect of Cassava Starch on Compressive Strength and Tear Strength of Alginate Impression Material</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mirna%20Febriani">Mirna Febriani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Statement of problem. Alginate impression material is an imported material and a dentist always used this material to make impression of teeth and oral cavity tissues. Purpose. The aim of this study was to compare about compressive strength and tear strength of alginate impression material and alginate impression material combined with cassava. Material and methods.Property measured included compressive strength and tear strength. Results.The compressive strength and tear strength of the impression materials tested of a comparable ANSI/ADA standard no.18.The compressive strength and tear strength alginate impression material combined with cassava have lower than the compressive strength and tear strength alginate impression material. The alginate impression material combined with cassava has more water and silica content more decrease than alginate impression material. Conclusions.We concluded that compressive strength and tear strength of alginate impression material combined with cassava has lower than alginate impression material without cassava starch. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=compressive%20strength" title="compressive strength">compressive strength</a>, <a href="https://publications.waset.org/abstracts/search?q=tear%20strength" title=" tear strength"> tear strength</a>, <a href="https://publications.waset.org/abstracts/search?q=Cassava%20starch" title=" Cassava starch"> Cassava starch</a>, <a href="https://publications.waset.org/abstracts/search?q=alginate" title=" alginate"> alginate</a> </p> <a href="https://publications.waset.org/abstracts/64938/the-effect-of-cassava-starch-on-compressive-strength-and-tear-strength-of-alginate-impression-material" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/64938.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">424</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">300</span> Polymer Nanocomposite Containing Silver Nanoparticles for Wound Healing</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Patr%C3%ADcia%20Severino">Patrícia Severino</a>, <a href="https://publications.waset.org/abstracts/search?q=Luciana%20Nalone"> Luciana Nalone</a>, <a href="https://publications.waset.org/abstracts/search?q=Daniele%20Martins"> Daniele Martins</a>, <a href="https://publications.waset.org/abstracts/search?q=Marco%20Chaud"> Marco Chaud</a>, <a href="https://publications.waset.org/abstracts/search?q=Classius%20Ferreira"> Classius Ferreira</a>, <a href="https://publications.waset.org/abstracts/search?q=Cristiane%20Bani"> Cristiane Bani</a>, <a href="https://publications.waset.org/abstracts/search?q=Ricardo%20Albuquerque"> Ricardo Albuquerque</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Hydrogels produced with polymers have been used in the development of dressings for wound treatment and tissue revitalization. Our study on polymer nanocomposites containing silver nanoparticles shows antimicrobial activity and applications in wound healing. The effects are linked with the slow oxidation and Ag⁺ liberation to the biological environment. Furthermore, bacterial cell membrane penetration and metabolic disruption through cell cycle disarrangement also contribute to microbial cell death. The silver antimicrobial activity has been known for many years, and previous reports show that low silver concentrations are safe for human use. This work aims to develop a hydrogel using natural polymers (sodium alginate and gelatin) combined with silver nanoparticles for wound healing and with antimicrobial properties in cutaneous lesions. The hydrogel development utilized different sodium alginate and gelatin proportions (20:80, 50:50 and 80:20). The silver nanoparticles incorporation was evaluated at the concentrations of 1.0, 2.0 and 4.0 mM. The physico-chemical properties of the formulation were evaluated using ultraviolet-visible (UV-Vis) absorption spectroscopy, Fourier transform infrared (FTIR) spectroscopy, differential scanning calorimetry (DSC), and thermogravimetric (TG) analysis. The morphological characterization was made using transmission electron microscopy (TEM). Human fibroblast (L2929) viability assay was performed with a minimum inhibitory concentration (MIC) assessment as well as an in vivo cicatrizant test. The results suggested that sodium alginate and gelatin in the (80:20) proportion with 4 mM of AgNO₃ in the (UV-Vis) exhibited a better hydrogel formulation. The nanoparticle absorption spectra of this analysis showed a maximum band around 430 - 450 nm, which suggests a spheroidal form. The TG curve exhibited two weight loss events. DSC indicated one endothermic peak at 230-250 °C, due to sample fusion. The polymers acted as stabilizers of a nanoparticle, defining their size and shape. Human fibroblast viability assay L929 gave 105 % cell viability with a negative control, while gelatin presented 96% viability, alginate: gelatin (80:20) 96.66 %, and alginate 100.33 % viability. The sodium alginate:gelatin (80:20) exhibited significant antimicrobial activity, with minimal bacterial growth at a ratio of 1.06 mg.mL⁻¹ in Pseudomonas aeruginosa and 0.53 mg.mL⁻¹ in Staphylococcus aureus. The in vivo results showed a significant reduction in wound surface area. On the seventh day, the hydrogel-nanoparticle formulation reduced the total area of injury by 81.14 %, while control reached a 45.66 % reduction. The results suggest that silver-hydrogel nanoformulation exhibits potential for wound dressing therapeutics. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=nanocomposite" title="nanocomposite">nanocomposite</a>, <a href="https://publications.waset.org/abstracts/search?q=wound%20healing" title=" wound healing"> wound healing</a>, <a href="https://publications.waset.org/abstracts/search?q=hydrogel" title=" hydrogel"> hydrogel</a>, <a href="https://publications.waset.org/abstracts/search?q=silver%20nanoparticle" title=" silver nanoparticle"> silver nanoparticle</a> </p> <a href="https://publications.waset.org/abstracts/99420/polymer-nanocomposite-containing-silver-nanoparticles-for-wound-healing" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/99420.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">101</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">299</span> Stability Study of Hydrogel Based on Sodium Alginate/Poly (Vinyl Alcohol) with Aloe Vera Extract for Wound Dressing Application</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Klaudia%20Pluta">Klaudia Pluta</a>, <a href="https://publications.waset.org/abstracts/search?q=Katarzyna%20Bialik-W%C4%85s"> Katarzyna Bialik-Wąs</a>, <a href="https://publications.waset.org/abstracts/search?q=Dagmara%20Malina"> Dagmara Malina</a>, <a href="https://publications.waset.org/abstracts/search?q=Mateusz%20Barczewski"> Mateusz Barczewski</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Hydrogel networks, due to their unique properties, are highly attractive materials for wound dressing. The three-dimensional structure of hydrogels provides tissues with optimal moisture, which supports the wound healing process. Moreover, a characteristic feature of hydrogels is their absorption properties which allow for the absorption of wound exudates. For the fabrication of biomedical hydrogels, a combination of natural polymers ensuring biocompatibility and synthetic ones that provide adequate mechanical strength are often used. Sodium alginate (SA) is one of the polymers widely used in wound dressing materials because it exhibits excellent biocompatibility and biodegradability. However, due to poor strength properties, often alginate-based hydrogel materials are enhanced by the addition of another polymer such as poly(vinyl alcohol) (PVA). This paper is concentrated on the preparation methods of sodium alginate/polyvinyl alcohol hydrogel system incorporating Aloe vera extract and glycerin for wound healing material with particular focus on the role of their composition on structure, thermal properties, and stability. Briefly, the hydrogel preparation is based on the chemical cross-linking method using poly(ethylene glycol) diacrylate (PEGDA, Mn = 700 g/mol) as a crosslinking agent and ammonium persulfate as an initiator. In vitro degradation tests of SA/PVA/AV hydrogels were carried out in Phosphate-Buffered Saline (pH – 7.4) as well as in distilled water. Hydrogel samples were firstly cut into half-gram pieces (in triplicate) and immersed in immersion fluid. Then, all specimens were incubated at 37°C and then the pH and conductivity values were measurements at time intervals. The post-incubation fluids were analyzed using SEC/GPC to check the content of oligomers. The separation was carried out at 35°C on a poly(hydroxy methacrylate) column (dimensions 300 x 8 mm). 0.1M NaCl solution, whose flow rate was 0.65 ml/min, was used as the mobile phase. Three injections with a volume of 50 µl were made for each sample. The thermogravimetric data of the prepared hydrogels were collected using a Netzsch TG 209 F1 Libra apparatus. The samples with masses of about 10 mg were weighed separately in Al2O3 crucibles and then were heated from 30°C to 900°C with a scanning rate of 10 °C∙min−1 under a nitrogen atmosphere. Based on the conducted research, a fast and simple method was developed to produce potential wound dressing material containing sodium alginate, poly(vinyl alcohol) and Aloe vera extract. As a result, transparent and flexible SA/PVA/AV hydrogels were obtained. The degradation experiments indicated that most of the samples immersed in PBS as well as in distilled water were not degraded throughout the whole incubation time. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hydrogels" title="hydrogels">hydrogels</a>, <a href="https://publications.waset.org/abstracts/search?q=wound%20dressings" title=" wound dressings"> wound dressings</a>, <a href="https://publications.waset.org/abstracts/search?q=sodium%20alginate" title=" sodium alginate"> sodium alginate</a>, <a href="https://publications.waset.org/abstracts/search?q=poly%28vinyl%20alcohol%29" title=" poly(vinyl alcohol)"> poly(vinyl alcohol)</a> </p> <a href="https://publications.waset.org/abstracts/144375/stability-study-of-hydrogel-based-on-sodium-alginatepoly-vinyl-alcohol-with-aloe-vera-extract-for-wound-dressing-application" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/144375.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">164</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">298</span> Surfactant-Modified Chitosan Beads: An Efficient and Cost Effective Material for Adsorptive Removal of Lead from Aqueous Solutions</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Preeti%20Pal">Preeti Pal</a>, <a href="https://publications.waset.org/abstracts/search?q=Anjali%20Pal"> Anjali Pal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Chitosan is an effective sorbent for removal of contaminants from wastewater. However, the ability of pure chitosan is specific because of its cationic charge. It causes repulsion in the removal process of various cationic charged molecules. The present study has been carried out for the successful removal of Pb²⁺ ions from aqueous solution by modified chitosan beads. Surface modification of chitosan (CS) beads was performed by using the anionic surfactant (AS), sodium dodecyl sulfate (SDS). Micelle aggregation property of SDS has been utilized for the formation of bilayer over the CS beads to produce surfactant modified chitosan (SMCS) beads. Prepared adsorbents were characterized by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) in order to find out their composition and surface morphology. SMCS beads, when compared to the pure CS beads, showed three times higher adsorption. This higher adsorption is believed to be due to the adsolubilization of Pb²⁺ ions on SDS bilayer. This bilayer provides more adsorption sites for quick and effective removal of Pb²⁺ ions from the aqueous phase. Moreover, the kinetic and adsorption isotherm models were employed to the obtained data for the description of the lead adsorption processes. It was found that the removal kinetics follows pseudo-second order model. Adsorption isotherm data fits well to the Langmuir model. The maximum adsorption capacity obtained is 100 mg/g at the dosage of 0.675 g/L for 50 mg/L of Pb²⁺. The adsorption capacity is subject to increase with increasing the Pb²⁺ ions concentration in the solution. The results indicated that the prepared hydrogel beads are efficient adsorbent for removal of Pb²⁺ ions from the aqueous medium. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adsolubilisation" title="adsolubilisation">adsolubilisation</a>, <a href="https://publications.waset.org/abstracts/search?q=anionic%20surfactant" title=" anionic surfactant"> anionic surfactant</a>, <a href="https://publications.waset.org/abstracts/search?q=bilayer" title=" bilayer"> bilayer</a>, <a href="https://publications.waset.org/abstracts/search?q=chitosan" title=" chitosan"> chitosan</a>, <a href="https://publications.waset.org/abstracts/search?q=Pb%C2%B2%E2%81%BA" title=" Pb²⁺"> Pb²⁺</a> </p> <a href="https://publications.waset.org/abstracts/70265/surfactant-modified-chitosan-beads-an-efficient-and-cost-effective-material-for-adsorptive-removal-of-lead-from-aqueous-solutions" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/70265.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">240</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">297</span> Hydrogel Hybridizing Temperature-Cured Dissolvable Gelatin Microspheres as Non-Anchorage Dependent Cell Carriers for Tissue Engineering Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dong-An%20Wang">Dong-An Wang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> All kinds of microspheres have been extensively employed as carriers for drug, gene and therapeutic cell delivery. Most therapeutic cell delivery microspheres rely on a two-step methodology: fabrication of microspheres and subsequent seeding of cells onto them. In this study, we have developed a novel one-step cell encapsulation technique using a convenient and instant water-in-oil single emulsion approach to form cell-encapsulated gelatin microspheres. This technology is adopted for hyaline cartilage tissue engineering, in which autologous chondrocytes are used as therapeutic cells. Cell viability was maintained throughout and after the microsphere formation (75-100 µm diameters) process that avoids involvement of any covalent bonding reactions or exposure to any further chemicals. Further encapsulation of cell-laden microspheres in alginate gels were performed under 4°C via a prompt process. Upon the formation of alginate constructs, they were immediately relocated into CO2 incubator where the temperature was maintained at 37°C; under this temperature, the cell-laden gelatin microspheres dissolved within hours to yield similarly sized cavities and the chondrocytes were therefore suspended within the cavities inside the alginate gel bulk. Hence, the gelatin cell-laden microspheres served two roles: as cell delivery vehicles which can be removable through temperature curing, and as porogens within an alginate hydrogel construct to provide living space for cell growth and tissue development as well as better permeability for mutual diffusions. These cell-laden microspheres, namely “temperature-cured dissolvable gelatin microsphere based cell carriers” (tDGMCs), were further encapsulated in a chondrocyte-laden alginate scaffold system and analyzed by WST-1, gene expression analyses, biochemical assays, histology and immunochemistry stains. The positive results consistently demonstrated the promise of tDGMC technology in delivering these non-anchorage dependent cells (chondrocytes). It can be further conveniently translated into delivery of other non-anchorage dependent cell species, including stem cells, progenitors or iPS cells, for regeneration of tissues in internal organs, such as engineered hepatogenesis or pancreatic regeneration. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biomaterials" title="biomaterials">biomaterials</a>, <a href="https://publications.waset.org/abstracts/search?q=tissue%20engineering" title=" tissue engineering"> tissue engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=microsphere" title=" microsphere"> microsphere</a>, <a href="https://publications.waset.org/abstracts/search?q=hydrogel" title=" hydrogel"> hydrogel</a>, <a href="https://publications.waset.org/abstracts/search?q=porogen" title=" porogen"> porogen</a>, <a href="https://publications.waset.org/abstracts/search?q=anchorage%20dependence" title=" anchorage dependence"> anchorage dependence</a> </p> <a href="https://publications.waset.org/abstracts/4056/hydrogel-hybridizing-temperature-cured-dissolvable-gelatin-microspheres-as-non-anchorage-dependent-cell-carriers-for-tissue-engineering-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/4056.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">396</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">296</span> Preparation and In vitro Characterization of Nanoparticle Hydrogel for Wound Healing</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rajni%20Kant%20Panik">Rajni Kant Panik</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of the present study was to develop and evaluate mupirocin loaded nanoparticle incorporated into hydrogel as an infected wound healer. Incorporated Nanoparticle in hydrogel provides a barrier that effectively prevents the contamination of the wound and further progression of infection to deeper tissues. Hydrogel creates moist healing environment on wound space with good fluid absorbance. Nanoparticles were prepared by double emulsion solvent evaporation method using different ratios of PLGA polymer and the hydrogels was developed using sodium alginate and gelatin. Further prepared nanoparticles were then incorporated into the hydrogels. The formulations were characterized by FT-IR and DSC for drug and polymer compatibility and surface morphology was studied by TEM. Nanoparticle hydrogel were evaluated for their size, shape, encapsulation efficiency and for in vitro studies. The FT-IR and DSC confirmed the absence of any drug polymer interaction. The average size of Nanoparticle was found to be in range of 208.21-412.33 nm and shape was found to be spherical. The maximum encapsulation efficiency was found to be 69.03%. The in vitro release profile of Nanoparticle incorporated hydrogel formulation was found to give sustained release of drug. Antimicrobial activity testing confirmed that encapsulated drug preserve its effectiveness. The stability study confirmed that the formulation prepared were stable. Present study complements our finding that mupirocin loaded Nanoparticle incorporated into hydrogel has the potential to be an effective and safe novel addition for the release of mupirocin in sustained manner, which may be a better option for the management of wound. These finding also supports the progression of antibiotic via hydrogel delivery system is a novel topical dosage form for the management of wound. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hydrogel" title="hydrogel">hydrogel</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoparticle" title=" nanoparticle"> nanoparticle</a>, <a href="https://publications.waset.org/abstracts/search?q=PLGA" title=" PLGA"> PLGA</a>, <a href="https://publications.waset.org/abstracts/search?q=wound%20healing" title=" wound healing"> wound healing</a> </p> <a href="https://publications.waset.org/abstracts/47734/preparation-and-in-vitro-characterization-of-nanoparticle-hydrogel-for-wound-healing" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/47734.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">311</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">295</span> The Role of Sodium Alginate in the Selective Flotation of Chalcopyrite Against Pyrite</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yufan%20Mu">Yufan Mu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The selective depression of pyrite in the flotation of copper minerals is difficult due to the activation of pyrite surface by copper ions. Novel depressants for pyrite are needed to responsibly extract copper resources for a greener and cleaner future. In this paper, the non-toxic sodium alginate was employed as a depressant to selectively separate chalcopyrite from pyrite in flotation using potassium amyl xanthate as the collector. The results from flotation tests showed that sodium alginate significantly depressed pyrite flotation while had slight influence on chalcopyrite flotation. The adsorption tests showed that the adsorption amount of sodium alginate on pyrite surface was much higher than that on chalcopyrite surface. The pre-adsorbed sodium alginate could effectively hinder the subsequent adsorption of collector on pyrite surface, thereby inhibiting pyrite flotation. The selective adsorption of sodium alginate on pyrite surface was caused by the interactions between the activating cuprous ions on pyrite surface and the carboxyl groups in sodium alginate. The paper shows that sodium alginate is a promising depressant for pyrite in the flotation of chalcopyrite. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chalcopyrite%20flotation" title="chalcopyrite flotation">chalcopyrite flotation</a>, <a href="https://publications.waset.org/abstracts/search?q=pyrite%20depression" title=" pyrite depression"> pyrite depression</a>, <a href="https://publications.waset.org/abstracts/search?q=sodium%20alginate" title=" sodium alginate"> sodium alginate</a>, <a href="https://publications.waset.org/abstracts/search?q=copper-activated%20pyrite" title=" copper-activated pyrite"> copper-activated pyrite</a>, <a href="https://publications.waset.org/abstracts/search?q=adsorption" title=" adsorption"> adsorption</a> </p> <a href="https://publications.waset.org/abstracts/165954/the-role-of-sodium-alginate-in-the-selective-flotation-of-chalcopyrite-against-pyrite" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/165954.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">83</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">294</span> The Study of Chitosan beads Adsorption Properties for the Removal of Heavy Metals</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Peter%20O.%20Osifo">Peter O. Osifo</a>, <a href="https://publications.waset.org/abstracts/search?q=Hein%20W.%20J.%20P.%20Neomagus"> Hein W. J. P. Neomagus</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, a predicted pH model was used to determine adsorption equilibrium properties of copper, lead, zinc and cadmium. Chitosan was prepared from the exoskeleton of Cape rock-lobsters, collected from the surroundings of Cape Town, South Africa. The beads were cross-linked with gluteraldehyde to restore its chemical stability in acid media. The chitosan beads were characterized; the beads water contents and pKa varied in the range of 90-96% and 4.3-6.0 respectively and the degree of crosslinking for the beads was 18%. A pH-model, which described the reversibility of the metal adsorbed onto the beads, was used to predict the equilibrium properties of copper, lead, zinc and cadmium adsorption onto the cross-linked beads. The model accounts for the effect of pH and the important model parameters; the equilibrium adsorption constant (Kads) and to a lesser extent the adsorbent adsorption capacity (qmax). The adsorption equilibrium constant for copper, lead, zinc and cadmium were found to be 2.58×10-3, 2.22×0-3, 9.55×0-3, and 4.79×0-3, respectively. The adsorbent maximum capacity was determined to be 4.2 mmol/g. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chitosan%20beads" title="chitosan beads">chitosan beads</a>, <a href="https://publications.waset.org/abstracts/search?q=adsorption" title=" adsorption"> adsorption</a>, <a href="https://publications.waset.org/abstracts/search?q=heavy%20metals" title=" heavy metals"> heavy metals</a>, <a href="https://publications.waset.org/abstracts/search?q=waste%20water" title=" waste water"> waste water</a> </p> <a href="https://publications.waset.org/abstracts/42098/the-study-of-chitosan-beads-adsorption-properties-for-the-removal-of-heavy-metals" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/42098.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">380</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">293</span> Hyaluronic Acid - Alginate Hydrogel for the Transdifferentiation of Testis Cells into Erythrocyte and Hepatocyte-like Cells; A Practice Within an Effective Agent Choice</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Leila%20Rashki%20Ghaleno">Leila Rashki Ghaleno</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamad%20Amin%20Hajari"> Mohamad Amin Hajari</a>, <a href="https://publications.waset.org/abstracts/search?q=Leila%20Montazeri"> Leila Montazeri</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdolhossein%20Shahverdi"> Abdolhossein Shahverdi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mojtaba%20Rezazadeh%20Valojerdi"> Mojtaba Rezazadeh Valojerdi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Spermatogonia stem cells (SSCs) exhibit pluripotency, enabling them to undergo differentiation into many cell lineages, including neurons, glia, endothelial cells, and hepatocytes when cultured in vitro. Although the specific mechanisms are not yet fully understood, it has been observed that biopolymer agents, such as hyaluronic acid (HA) and alginate (Alg), have the potential to induce transdifferentiation of SSCs. The current work aimed to examine the process of in vitro spermatogenesis and the conversion of mouse testicular cells into hepatocytes and erythrocyte-like cells utilizing the HA-Alg hydrogel. Method: After being extracted from the testes of a 5-day postpartum mouse (5 DPP), the testicular cells were separated into two enzymatic stages and then put into a composite hydrogel containing 0.5% HA and 1% alginate. On days 14 and 28 of culture, the colonies' growth, the cells' viability, and their histology were assessed. Result: Despite observing significant cell proliferation on day 14 and the development of circular-shaped organoids on day 28, it was noted that the organoids generated in the HA-Alg medium tended to maintain their circular morphology on day 28. Notably, the testicular cells underwent transdifferentiation into cell types resembling erythrocytes and hepatocytes. The hepatocyte-like cells exhibited the presence of glycogen and lipid deposits, indicating their hepatocyte-like characteristics. Interestingly, immunostaining analysis revealed the secretion of albumin and the presence of VEGFR on day 14. However, on day 28, albumin expression was not detected, while the expression of Sox9 (a marker for hepatocytes), Vegf, CD34, and C-kit (markers for erythrocytes) showed increased levels in the gene expression evaluation. Conclusion: The present findings indicated that HA-Alg could be a potent and effective agent for the transdifferentiation of testis cells into erythrocyte and hepatocyte-like cells, as recent studies have confirmed the transformation of SSCs into hepatocyte cells during in vitro culture. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=3D%20culture" title="3D culture">3D culture</a>, <a href="https://publications.waset.org/abstracts/search?q=mouse%20testicular%20cell" title=" mouse testicular cell"> mouse testicular cell</a>, <a href="https://publications.waset.org/abstracts/search?q=hyaluronic%20acid" title=" hyaluronic acid"> hyaluronic acid</a>, <a href="https://publications.waset.org/abstracts/search?q=liver%20organoids" title=" liver organoids"> liver organoids</a> </p> <a href="https://publications.waset.org/abstracts/171962/hyaluronic-acid-alginate-hydrogel-for-the-transdifferentiation-of-testis-cells-into-erythrocyte-and-hepatocyte-like-cells-a-practice-within-an-effective-agent-choice" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/171962.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">71</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">292</span> Polymerization: An Alternative Technology for Heavy Metal Removal </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20S.%20Mahmoud">M. S. Mahmoud</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this paper, the adsorption performance of a novel environmental friendly material, calcium alginate gel beads as a non-conventional technique for the successful removal of copper ions from aqueous solution are reported on. Batch equilibrium studies were carried out to evaluate the adsorption capacity and process parameters such as pH, adsorbent dosages, initial metal ion concentrations, stirring rates and contact times. It was observed that the optimum pH for maximum copper ions adsorption was at pH 5.0. For all contact times, an increase in copper ions concentration resulted in decrease in the percent of copper ions removal. Langmuir and Freundlich's isothermal models were used to describe the experimental adsorption. Adsorbent was characterization using Fourier transform-infrared (FT-IR) spectroscopy and Transmission electron microscopy (TEM). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adsorption" title="adsorption">adsorption</a>, <a href="https://publications.waset.org/abstracts/search?q=alginate%20polymer" title=" alginate polymer"> alginate polymer</a>, <a href="https://publications.waset.org/abstracts/search?q=isothermal%20models" title=" isothermal models"> isothermal models</a>, <a href="https://publications.waset.org/abstracts/search?q=equilibrium" title=" equilibrium"> equilibrium</a> </p> <a href="https://publications.waset.org/abstracts/18708/polymerization-an-alternative-technology-for-heavy-metal-removal" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/18708.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">448</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">291</span> Preparation and Characterizations of Hydroxyapatite-Sodium Alginate Nanocomposites for Biomedical Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Friday%20Godwin%20Okibe">Friday Godwin Okibe</a>, <a href="https://publications.waset.org/abstracts/search?q=Christian%20Chinweuba%20Onoyima"> Christian Chinweuba Onoyima</a>, <a href="https://publications.waset.org/abstracts/search?q=Edith%20Bolanle%20Agbaji"> Edith Bolanle Agbaji</a>, <a href="https://publications.waset.org/abstracts/search?q=Victor%20Olatunji%20Ajibola"> Victor Olatunji Ajibola</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Polymer-inorganic nanocomposites are presently impacting diverse areas, specifically in biomedical sciences. In this research, hydroxyapatite-sodium alginate has been prepared, and characterized, with emphasis on the influence of sodium alginate on its characteristics. In situ wet chemical precipitation method was used in the preparation. The prepared nanocomposite was characterized with Fourier Transform Infrared spectroscopy (FTIR), Scanning Electron Microscopy (SEM), with image analysis, and X-Ray Diffraction (XRD). The FTIR study shows peaks characteristics of hydroxyapatite and confirmed formation of the nanocomposite via chemical interaction between sodium alginate and hydroxyapatite. Image analysis shows the nanocomposites to be of irregular morphologies which did not show significant change with increasing sodium alginate addition, while particle size decreased with increase in sodium alginate addition (359.46 nm to 109.98 nm). From the XRD data, both the crystallite size and degree of crystallinity also decreased with increasing sodium alginate composition (32.36 nm to 9.47 nm and 72.87% to 1.82% respectively), while the specific surface area and microstrain increased with increasing sodium alginate composition (0.0041 to 0.0139 and 58.99 m²/g to 201.58 m²/g respectively). The results show that the formulation with 50%wt of sodium alginate (HASA-50%wt), possess exceptional characteristics for biomedical applications such as drug delivery. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=nanocomposite" title="nanocomposite">nanocomposite</a>, <a href="https://publications.waset.org/abstracts/search?q=sodium%20alginate" title=" sodium alginate"> sodium alginate</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=biomedical" title=" biomedical"> biomedical</a>, <a href="https://publications.waset.org/abstracts/search?q=FTIR" title=" FTIR"> FTIR</a>, <a href="https://publications.waset.org/abstracts/search?q=XRD" title=" XRD"> XRD</a>, <a href="https://publications.waset.org/abstracts/search?q=SEM" title=" SEM"> SEM</a> </p> <a href="https://publications.waset.org/abstracts/66789/preparation-and-characterizations-of-hydroxyapatite-sodium-alginate-nanocomposites-for-biomedical-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/66789.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">330</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">290</span> Application of Chemical Tests for the Inhibition of Scaling From Hamma Hard Waters</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Samira%20Ghizellaoui">Samira Ghizellaoui</a>, <a href="https://publications.waset.org/abstracts/search?q=Manel%20Boumagoura"> Manel Boumagoura</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Calcium carbonate precipitation is a widespread problem, especially in hard water systems. The main water supply that supplies the city of Constantine with drinking water is underground water called Hamma water. This water has a very high hardness of around 590 mg/L CaCO₃. This leads to the formation of scale, consisting mainly of calcium carbonate, which can be responsible for the clogging of valves and the deterioration of equipment (water heaters, washing machines and encrustations in the pipes). Plant extracts used as scale inhibitors have attracted the attention of several researchers. In recent years, green inhibitors have attracted great interest because they are biodegradable, non-toxic and do not affect the environment. The aim of our work is to evaluate the effectiveness of a chemical antiscale treatment in the presence of three green inhibitors: gallicacid; quercetin; alginate, and three mixtures: (gallic acid-quercetin); (quercetin-alginate); (gallic acid-alginate). The results show that the inhibitory effect is manifested from an addition of 1mg/L of gallic acid, 10 mg/L of quercetin, 0.2 mg/L of alginate, 0.4mg/L of (gallic acid-quercetin), 2mg/L of (quercetin-alginate) and 0.4 mg/L of (gallic acid-alginate). On the other hand, 100 mg/L (Drinking water standard) of Ca2+is reached for partial softening at 4 mg/L of gallic acid, 40 mg/L of quercetin, 0.6mg/L of alginate, 4mg/L of (gallic acid-quercetin), 10mg/L of (quercetin-alginate) and 1.6 mg/L of (gallic acid-alginate). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=water" title="water">water</a>, <a href="https://publications.waset.org/abstracts/search?q=scaling" title=" scaling"> scaling</a>, <a href="https://publications.waset.org/abstracts/search?q=calcium%20carbonate" title=" calcium carbonate"> calcium carbonate</a>, <a href="https://publications.waset.org/abstracts/search?q=green%20inhibitor" title=" green inhibitor"> green inhibitor</a> </p> <a href="https://publications.waset.org/abstracts/167612/application-of-chemical-tests-for-the-inhibition-of-scaling-from-hamma-hard-waters" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/167612.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">68</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">289</span> Optimization of Hydrogel Conductive Nanocomposite as Solar Cell</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shimaa%20M.%20Elsaeed">Shimaa M. Elsaeed</a>, <a href="https://publications.waset.org/abstracts/search?q=Reem%20K.%20Farag"> Reem K. Farag</a>, <a href="https://publications.waset.org/abstracts/search?q=Ibrahim%20M.%20Nassar"> Ibrahim M. Nassar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Hydrogel conductive polymer nanocomposite fabricated via in-situ polymerization of polyaniline (PANI) inside thermosensitive hydrogels based on hydroxy ethyl meth acrylate (HEMA) copolymer with 2-acrylamido-2-methyl propane sulfonic acid (AMPS). SEM micrographs show the nanometric size of the conductive material (polyaniline, PANI) dispersed in the hydrogel matrix. The swelling parameters of hydrogel are measured. The incorporation of PANI improves the mechanical properties and swelling up to 30,000% without breaking. X-ray diffraction shows that typical polyaniline crystallization is formed in composite, which is advantageous to increase the electrical conductivity of the composite hydrogel. Open-circuit voltage (I-V) curve fill factor of the highest photo-conversion efficiency and enhanced to use in solar cell. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hydrogel" title="hydrogel">hydrogel</a>, <a href="https://publications.waset.org/abstracts/search?q=solar%20cell" title=" solar cell"> solar cell</a>, <a href="https://publications.waset.org/abstracts/search?q=conductive%20polymer" title=" conductive polymer"> conductive polymer</a>, <a href="https://publications.waset.org/abstracts/search?q=nanocomposite" title=" nanocomposite"> nanocomposite</a> </p> <a href="https://publications.waset.org/abstracts/42489/optimization-of-hydrogel-conductive-nanocomposite-as-solar-cell" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/42489.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">399</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">288</span> Fabrication of Antimicrobial Dental Model Using Digital Light Processing (DLP) Integrated with 3D-Bioprinting Technology</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rana%20Mohamed">Rana Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20E.%20Gomaa"> Ahmed E. Gomaa</a>, <a href="https://publications.waset.org/abstracts/search?q=Gehan%20Safwat"> Gehan Safwat</a>, <a href="https://publications.waset.org/abstracts/search?q=Ayman%20Diab"> Ayman Diab</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Bio-fabrication is a multidisciplinary research field that combines several principles, fabrication techniques, and protocols from different fields. The open-source-software movement is a movement that supports the use of open-source licenses for some or all software as part of the broader notion of open collaboration. Additive manufacturing is the concept of 3D printing, where it is a manufacturing method through adding layer-by-layer using computer-aided designs (CAD). There are several types of AM system used, and they can be categorized by the type of process used. One of these AM technologies is Digital light processing (DLP) which is a 3D printing technology used to rapidly cure a photopolymer resin to create hard scaffolds. DLP uses a projected light source to cure (Harden or crosslinking) the entire layer at once. Current applications of DLP are focused on dental and medical applications. Other developments have been made in this field, leading to the revolutionary field 3D bioprinting. The open-source movement was started to spread the concept of open-source software to provide software or hardware that is cheaper, reliable, and has better quality. Objective: Modification of desktop 3D printer into 3D bio-printer and the integration of DLP technology and bio-fabrication to produce an antibacterial dental model. Method: Modification of a desktop 3D printer into a 3D bioprinter. Gelatin hydrogel and sodium alginate hydrogel were prepared with different concentrations. Rhizome of Zingiber officinale, Flower buds of Syzygium aromaticum, and Bulbs of Allium sativum were extracted, and extractions were selected on different levels (Powder, aqueous extracts, total oils, and Essential oils) prepared for antibacterial bioactivity. Agar well diffusion method along with the E. coli have been used to perform the sensitivity test for the antibacterial activity of the extracts acquired by Zingiber officinale, Syzygium aromaticum, and Allium sativum. Lastly, DLP printing was performed to produce several dental models with the natural extracted combined with hydrogel to represent and simulate the Hard and Soft tissues. Result: The desktop 3D printer was modified into 3D bioprinter using open-source software Marline and modified custom-made 3D printed parts. Sodium alginate hydrogel and gelatin hydrogel were prepared at 5% (w/v), 10% (w/v), and 15%(w/v). Resin integration with the natural extracts of Rhizome of Zingiber officinale, Flower buds of Syzygium aromaticum, and Bulbs of Allium sativum was done following the percentage 1- 3% for each extract. Finally, the Antimicrobial dental model was printed; exhibits the antimicrobial activity, followed by merging with sodium alginate hydrogel. Conclusion: The open-source movement was successful in modifying and producing a low-cost Desktop 3D Bioprinter showing the potential of further enhancement in such scope. Additionally, the potential of integrating the DLP technology with bioprinting is a promising step toward the usage of the antimicrobial activity using natural products. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=3D%20printing" title="3D printing">3D printing</a>, <a href="https://publications.waset.org/abstracts/search?q=3D%20bio-printing" title=" 3D bio-printing"> 3D bio-printing</a>, <a href="https://publications.waset.org/abstracts/search?q=DLP" title=" DLP"> DLP</a>, <a href="https://publications.waset.org/abstracts/search?q=hydrogel" title=" hydrogel"> hydrogel</a>, <a href="https://publications.waset.org/abstracts/search?q=antibacterial%20activity" title=" antibacterial activity"> antibacterial activity</a>, <a href="https://publications.waset.org/abstracts/search?q=zingiber%20officinale" title=" zingiber officinale"> zingiber officinale</a>, <a href="https://publications.waset.org/abstracts/search?q=syzygium%20aromaticum" title=" syzygium aromaticum"> syzygium aromaticum</a>, <a href="https://publications.waset.org/abstracts/search?q=allium%20sativum" title=" allium sativum"> allium sativum</a>, <a href="https://publications.waset.org/abstracts/search?q=panax%20ginseng" title=" panax ginseng"> panax ginseng</a>, <a href="https://publications.waset.org/abstracts/search?q=dental%20applications" title=" dental applications"> dental applications</a> </p> <a href="https://publications.waset.org/abstracts/153864/fabrication-of-antimicrobial-dental-model-using-digital-light-processing-dlp-integrated-with-3d-bioprinting-technology" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/153864.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">94</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">287</span> The Influence of Alginate Microspheres Modified with DAT on the Proliferation and Adipogenic Differentiation of ASCs</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shin-Yi%20Mao">Shin-Yi Mao</a>, <a href="https://publications.waset.org/abstracts/search?q=Jiashing%20Yu"> Jiashing Yu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Decellularized adipose tissue (DAT) has received lots of attention as biological scaffolds recently. DAT that extracted from the extracellular matrix (ECM) of adipose tissues holds great promise as a xenogeneic biomaterial for tissue engineering and regenerative medicine. In our study, 2-D DATsol film was fabricated to enhance cell adhesion, proliferation, and differentiation of ASCs in vitro. DAT was also used to modify alginate for improvement of cell adhesion. Alginate microspheres modified with DAT were prepared by Nisco. These microspheres could provide a highly supportive 3-D environment for ASCs. In our works, ASCs were immobilized in alginate microspheres modified with DAT to promoted cell adhesion and adipogenic differentiation. Accordingly, we hypothesize that tissue regeneration in vivo could be promoted with the aid of modified microspheres in future. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adipose%20stem%20cells" title="adipose stem cells">adipose stem cells</a>, <a href="https://publications.waset.org/abstracts/search?q=decellularize%20adipose%20tissue" title=" decellularize adipose tissue"> decellularize adipose tissue</a>, <a href="https://publications.waset.org/abstracts/search?q=Alginate" title=" Alginate"> Alginate</a>, <a href="https://publications.waset.org/abstracts/search?q=microcarries" title=" microcarries"> microcarries</a> </p> <a href="https://publications.waset.org/abstracts/13276/the-influence-of-alginate-microspheres-modified-with-dat-on-the-proliferation-and-adipogenic-differentiation-of-ascs" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/13276.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">444</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">&lsaquo;</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=alginate%20hydrogel%20beads&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=alginate%20hydrogel%20beads&page=3">3</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=alginate%20hydrogel%20beads&page=4">4</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=alginate%20hydrogel%20beads&page=5">5</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=alginate%20hydrogel%20beads&page=6">6</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=alginate%20hydrogel%20beads&page=7">7</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=alginate%20hydrogel%20beads&page=8">8</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=alginate%20hydrogel%20beads&page=9">9</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=alginate%20hydrogel%20beads&page=10">10</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=alginate%20hydrogel%20beads&page=11">11</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=alginate%20hydrogel%20beads&page=2" rel="next">&rsaquo;</a></li> 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