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Pathomechanismen - Nephropathologie | Uniklinikum Erlangen

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"><span>Pathomechanismen und Modulation der gest枚rten Angiogenese bei chronischer Niereninsuffizienz</span></h2></div><p>Dieses Projekt wird zusammen mit Prof. Dr. K.F. Hilgers aus der Medizinischen Klinik 4 bearbeitet. Die Sterblichkeitsrate von Patienten mit chronischer Niereninsuffizienz (CKD) ist so hoch wie bei Malignomen und v. a. kardiovaskul盲r begr眉ndet. Patienten mit CKD zeigen charakteristische strukturelle Herz- und Gef盲脽ver盲nderungen. Eigene Vorbefunde und Arbeiten anderer legen nahe, dass eine verminderte Kapazit盲t zur Neubildung von Kapillargef盲脽en sowie zur Adaptation bestehender Gef盲脽e, insbesondere bei Organhypertrophie oder -isch盲mie, eine wichtige Rolle bei diesem klinisch relevanten Problem spielen. 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