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Addgene: Mission

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<ul class="col-xs-4 menu-column list-unstyled"> <li class="menu-heading" tabindex="0"><img src="https://static.addgene.org/addgene-core/ba538e0eee/images/public/icons/icon-clipboard.svg" alt="">Ordering & MTAs </li> <li><a href="https://help.addgene.org/hc/en-us/articles/205436319">How do I place an order? Does Addgene accept orders by fax, phone or email?</a></li> <li><a href="https://help.addgene.org/hc/en-us/sections/201196819">What is an MTA/Who is authorized to sign?</a></li> <li><a href="https://help.addgene.org/hc/en-us/articles/206133495">How do I get a quote?</a></li> <li><a href="https://help.addgene.org/hc/en-us/articles/206133555">What do I need to know about the customs and importation process for my country?</a></li> <li><a href="https://help.addgene.org/hc/en-us/categories/200491659">View all Ordering & MTA articles</a></li> </ul> <ul class="col-xs-4 menu-column list-unstyled"> <li class="menu-heading" tabindex="0"><img src="https://static.addgene.org/addgene-core/ba538e0eee/images/public/icons/icon-support.svg" alt="">Technical Support </li> <li><a href="https://help.addgene.org/hc/en-us/articles/360019863351">Can you help me find a plasmid?</a> </li> <li><a href="https://help.addgene.org/hc/en-us/articles/205433649">There is a problem with the plasmid I received.</a></li> <li><a href="https://help.addgene.org/hc/en-us/articles/205433549">My stab did not grow. What do I do?</a> </li> <li><a href="https://help.addgene.org/hc/en-us/articles/360031227692">What strain of bacteria does my stab contain?</a></li> <li><a href="https://help.addgene.org/hc/en-us/articles/205434539">How can I be notified when a new material becomes available?</a></li> <li><a href="https://help.addgene.org/hc/en-us/articles/360025306932">What services does Addgene provide?</a></li> <li><a href="https://help.addgene.org/hc/en-us/categories/200491649">View all Technical Support articles</a></li> </ul> <ul class="col-xs-4 menu-column list-unstyled"> <li class="menu-heading" tabindex="0"><img src="https://static.addgene.org/addgene-core/ba538e0eee/images/public/icons/icon-depositing.svg" alt="">Depositing Plasmids </li> <li><a href="https://help.addgene.org/hc/en-us/articles/205440209">How do I prepare and deposit my plasmids?</a></li> <li><a href="https://help.addgene.org/hc/en-us/articles/206135585">Which plasmids should I deposit?</a> </li> <li><a href="https://help.addgene.org/hc/en-us/articles/206135605">How can I track requests for my plasmids?</a></li> <li><a href="https://help.addgene.org/hc/en-us/articles/360019620672">What are Rewards Points?</a></li> <li><a href="https://help.addgene.org/hc/en-us/categories/200507955">View all Depositing Plasmids articles</a></li> </ul> </div> <div class="row-wide-gutters menu-multiple-row d-flex"> <div class="col-xs-4 menu-column"> <ul class="list-unstyled"> <li class="menu-heading" tabindex="0"><img src="https://static.addgene.org/addgene-core/ba538e0eee/images/public/icons/icon-virus-monochrome.svg" alt="">Viral Preps & Antibodies </li> <li><a href="https://help.addgene.org/hc/en-us/articles/115000050726">What is virus associated DNA, and why do I have to order it?</a></li> <li><a href="https://help.addgene.org/hc/en-us/articles/211773603">What virus titer will I receive?</a> </li> <li><a href="https://help.addgene.org/hc/en-us/articles/211770763">Viral storage</a></li> <li><a href="https://help.addgene.org/hc/en-us/articles/4584105031949">Antibody storage</a></li> <li><a href="https://help.addgene.org/hc/en-us/categories/201416626">View All Viral Preps & Antibodies articles</a></li> </ul> </div> <div class="col-xs-4 menu-column list-unstyled"> <ul class="list-unstyled"> <li class="menu-heading" tabindex="0"><img src="https://static.addgene.org/addgene-core/ba538e0eee/images/public/icons/icon-package.svg" alt="">Plasmid Handling </li> <li><a href="https://help.addgene.org/hc/en-us/articles/360019194111">Bacterial stab</a></li> <li><a href="https://help.addgene.org/hc/en-us/articles/206127485">DNA</a></li> <li><a href="https://help.addgene.org/hc/en-us/articles/360027736172">Pooled library</a></li> <li><a href="https://help.addgene.org/hc/en-us/sections/201190479">Kit</a></li> <li><a href="https://help.addgene.org/hc/en-us/articles/205432549">Plasmid verification</a></li> <li><a href="https://help.addgene.org/hc/en-us/categories/200491639">View all Plasmid Handling articles</a></li> </ul> </div> <div class="col-xs-4 menu-column"> <div class="row-wide-gutters menu-multiple-row"> <ul class="col-xs-12 list-unstyled"> <li class="menu-heading" tabindex="0"><img src="https://static.addgene.org/addgene-core/ba538e0eee/images/public/icons/icon-transfer.svg" alt="">Technology Transfer </li> <li><a href="/techtransfer/">Resources for your Tech Transfer Office</a></li> </ul> </div> <div class="row-wide-gutters menu-multiple-row"> <ul class="col-xs-12 list-unstyled"> <li class="menu-heading" tabindex="0"><img src="https://static.addgene.org/addgene-core/ba538e0eee/images/public/icons/icon-question.svg" alt="">Access the Help Center </li> <li><a href="https://help.addgene.org/">View all Help Center articles</a></li> </ul> </div> </div> </div> </div> </div> </div> <div class="dropdown-bg"></div> </div> </div> </nav> </div> </header> <div id="page-body"> <main id="main-content"> <div class="container" tabindex="-1"> <!-- Mission Section --> <div class="row"> <div class="banner"> <div class ="banner-text"> <h1 class= "page-title" id="title-desktop"> Addgene's Mission</h1> <h1 class= "page-title" id="title-mobile"> Addgene's Mission </h1> </div> </div> </div> <section class="mission"> <div id="mission-text"> <h2 class="section-title">Our Mission</h2> <p><i>Accelerate research and discovery by improving access to useful research materials and information.</i> </p> </div> </section> <hr> <!-- Services Section --> <section id="services"> <h2 class="section-title">Our Services</h2> <div class="row service-row"> <a href="/deposit/"> <div class="col-lg-3 col-xs-4"> <div class="panel panel-style service"> <div class="panel-heading"> <h3 class="panel-title">Deposit</h3> </div> <div class="panel-body"> <p class="service-text"><span class="link-text">Deposit your plasmids</span> with Addgene and we will handle storage, distribution, and record-keeping.</p> </div> </div> </div> </a> <div class="col-xs-8 service-text"> <p>Addgene is a global, nonprofit repository that was created to help scientists share plasmids. <a href="/mol-bio-reference/#plasmids">Plasmids</a> are DNA-based research reagents commonly used in the life sciences. When scientists publish research papers, they <b class="buzzword">deposit</b> their associated plasmids at Addgene. Then, when other scientists read the publication, they have easy access to the plasmids needed to conduct future experiments. Before Addgene, scientists were tasked with repeatedly shipping plasmids to each new requesting scientist. Now, scientists ship their plasmids to Addgene once, and we take care of the quality control, MTA compliance, shipping, and record-keeping. </p> </div> </div> <div class="row service-row"> <a href="/ordering/"> <div class="col-lg-3 col-xs-4"> <div class="panel panel-style service"> <div class="panel-heading"> <h3 class="panel-title">Request</h3> </div> <div class="panel-body"> <p class="service-text"><span class="link-text">Request plasmids and ready-to use viral preparations</span> from our vast online collection.</p> </div> </div> </div> </a> <div class="col-xs-8 service-text"> <p>For scientists looking to use plasmids, Addgene provides a searchable database of high-quality plasmids, pooled libraries, and plasmid kits, available at affordable prices. All plasmids in Addgene鈥檚 repository are sequenced for quality control purposes and tracked with barcodes from the time they arrive at our facility until they are packed for shipment. Scientists can <b class="buzzword">request</b> plasmids through Addgene鈥檚 online ordering system. As of 2016, Addgene also provides ready-to-use AAV and lentivirus preparations of commonly requested plasmids as a service to scientists. </p> </div> </div> <div class="row"> <a href="/plasmid-reference/"> <div class="col-lg-3 col-xs-4"> <div class="panel panel-style service"> <div class="panel-heading"> <h3 class="panel-title">Learn</h3> </div> <div class="panel-body"> <p class="service-text"><span class="link-text">Learn something new</span> from our educational resources, e-books, and blog.</p> </div> </div> </div> </a> <div class="col-xs-8 service-text"> <p>Addgene is also building a variety of educational resources, including protocols, blog posts, and eBooks. Our Plasmids 101 and CRISPR 101 blog series were designed to help scientists of all levels <b class="buzzword">learn</b> more about molecular biology, cloning, genome engineering, and more. Addgene鈥檚 technical support team also provides scientists with real-time plasmid troubleshooting - whether it鈥檚 a question about mutations in a plasmid sequence or help selecting the best plasmid for an experiment. By providing these services, Addgene鈥檚 goal is to create a lasting resource for research and discovery around the world. </p> </div> </div> </section> <div id="intro-cta"> <a href="https://youtu.be/c7J883VKY0I" target="_blank" rel="noopener noreferrer"><strong><u>Click Here to watch the Introduction to Addgene video</u></strong> </a> </div> <hr> <!-- Story Section --> <!-- Vertical Timeline Section --> <div class="story"> <h2 id="story-title" class="section-title">Our Story</h2> <ul class="timeline"> <li class="timeline-item"> <div class="panel panel-info timeline-panel"> <div class="panel-heading"> <h4 class="panel-title">Addgene Founded <p class="pull-right"><small class="text-muted">January 2004</small></p> </h4> </div> <div class="panel-body"> <p>Addgene was founded on January 8, 2004 by Melina Fan, Kenneth Fan, and Benjie Chen. <a href="#more-foundation" data-toggle="collapse" aria-expanded="false" aria-controls="more-foundation" class="collapsed">Read more <b class="caret"></b></a></p> <div class="collapse" id="more-foundation"> <p>After frustrations around plasmid sharing during grad school, Melina teamed up with her brother Ken and husband Benjie to start Addgene, a <a href="http://blog.addgene.org/addgenes-a-nonprofit-nonprofit-awareness-day-2017" target="_blank" rel="noopener noreferrer">nonprofit</a> plasmid repository. The founders hoped that the repository would make it easy for scientists to share materials and thereby accelerate research.</p> </div> </div> </div> </li> <li class="timeline-item"> <div class="panel panel-info timeline-panel"> <div class="panel-heading"> <h4 class="panel-title">First Plasmid Requested <p class="pull-right"><small class="text-muted">September 2004</small></p> </h4> </div> <div class="panel-body"> <p>On September 8, 2004, the first request for a plasmid, pcDNA-p160MBP, was made from Addgene. <a href="#more-plasmid" data-toggle="collapse" aria-expanded="false" aria-controls="more-plasmid" class="collapsed">Read more <b class="caret"></b></a></p> <div class="collapse" id="more-plasmid"> <p>Now a red flame plasmid, <a href="/41/" target="_blank" rel="noopener noreferrer">pcDNA-p160MBP</a> from Bruce Spiegelman鈥檚 lab can be used to express the p160 myb binding protein in mammalian cells.</p> </div> </div> </div> </li> </ul> <ul class="timeline"> <li class="timeline-item"> <div class="panel panel-info timeline-panel"> <div class="panel-heading"> <h4 class="panel-title">First Kit Requested <p class="pull-right"><small class="text-muted">March 2005</small></p> </h4> </div> <div class="panel-body"> <p>On March 9, 2005, the first request for a kit, the Fire lab <i>C. Elegans</i> Kit, was made from Addgene. <a href="#more-kit" data-toggle="collapse" aria-expanded="false" aria-controls="more-kit" class="collapsed">Read more <b class="caret"></b></a></p> <div class="collapse" id="more-kit"> <p><a href="/kits/firelab/" target="_blank" rel="noopener noreferrer">The Fire lab kit</a>, which is still widely requested today, provides researchers with a wide variety of plasmid tools that they can use to accelerate their <i>C. elegans</i> research.</p> </div> </div> </div> </li> <li class="timeline-item"> <div class="panel panel-info timeline-panel"> <div class="panel-heading"> <h4 class="panel-title">10,000 Plasmids Available <p class="pull-right"><small class="text-muted">January 2010</small></p> </h4> </div> <div class="panel-body"> <p>On January 6, 2010, Addgene's repository reached the 10,000 plasmid milestone. </p> </div> </div> </li> </ul> <ul class="timeline"> <li class="timeline-item"> <div class="panel panel-info timeline-panel"> <div class="panel-heading"> <h4 class="panel-title">1,000 Depositing Scientists <p class="pull-right"><small class="text-muted">December 2011</small></p> </h4> </div> <div class="panel-body"> <p>On December 19, 2011, Addgene's community of depositing scientists reached 1,000 members. <a href="#more-deposits" data-toggle="collapse" aria-expanded="false" aria-controls="more-deposits" class="collapsed">Read more <b class="caret"></b></a></p> <div class="collapse" id="more-deposits"> <p>Although it took 7 years to reach this 1,000 depositor benchmark, Addgene continued to grow rapidly in the years that followed. As of June 2017, there are over 3,000 depositors who rely on Addgene to distribute their materials efficiently.</p> </div> </div> </div> </li> <li class="timeline-item"> <div class="panel panel-info timeline-panel"> <div class="panel-heading"> <h4 class="panel-title">First CRISPR Plasmids Deposited <p class="pull-right"><small class="text-muted">September 2012</small></p> </h4> </div> <div class="panel-body"> <p>CRISPR is making it easier than ever for biologists studying organisms of all kinds to make precise genomic changes. <a href="#more-crispr" data-toggle="collapse" aria-expanded="false" aria-controls="more-crispr" class="collapsed">Read more <b class="caret"></b></a></p> <div class="collapse" id="more-crispr"> <p>The developers of this amazing new technology have been incredibly supportive of open sharing and have distributed <a href="/crispr/">CRISPR tools</a> through Addgene since CRISPR鈥檚 debut. This mindset has facilitated CRISPR鈥檚 rapid adoption. As of July 2017, over 95,000 CRISPR plasmids and pooled libraries have been requested through Addgene. </p> </div> </div> </div> </li> </ul> <ul class="timeline"> <li class="timeline-item"> <div class="panel panel-info timeline-panel"> <div class="panel-heading"> <h4 class="panel-title">Mass. Nonprofit Network Excellence Award <p class="pull-right"><small class="text-muted">June 2013</small></p> </h4> </div> <div class="panel-body"> <p>Addgene wins the Massachusetts Nonprofit Network Excellence Award for our electronic MTA system.<br> <a href="#more-award" data-toggle="collapse" aria-expanded="false" aria-controls="more-award" class="collapsed">Read more <b class="caret"></b></a></p> <div class="collapse" id="more-award"> <p>Addgene's <a href="/techtransfer/#request">electronic MTA system</a> streamlines the legal approval process involved in plasmid sharing. Legal agreements that used to take months to get approval can now be approved almost instantly. As a result, most Addgene customers receive their plasmids within a week of placing their order. </p> </div> </div> </div> </li> <li class="timeline-item"> <div class="panel panel-info timeline-panel"> <div class="panel-heading"> <h4 class="panel-title">Addgene's UK Branch Opens <p class="pull-right"><small class="text-muted">June 2014</small></p> </h4> </div> <div class="panel-body"> <p>On June 4, 2014, in partnership with LGC Standards, Addgene opened a satellite office in Teddington, UK. <a href="#more-uk" data-toggle="collapse" aria-expanded="false" aria-controls="more-uk" class="collapsed">Read more <b class="caret"></b></a></p> <div class="collapse" id="more-uk"> <p>The goal of this <a href="/news/london-office/">new UK office</a> was to better serve our international customers. As of 2013, over 50% of Addgene orders were international. Having office hours 9am-5pm GMT, the UK office enables Addgene to better serve and engage with customers from around the globe. </p> </div> </div> </div> </li> </ul> <ul class="timeline"> <li class="timeline-item"> <div class="panel panel-info timeline-panel"> <div class="panel-heading"> <h4 class="panel-title">Davidson Collection Deposited <p class="pull-right"><small class="text-muted">July 2014</small></p> </h4> </div> <div class="panel-body"> <p>With over 3,300 plasmids, the Michael Davidson Fluorescent Protein Collection was Addgene's largest deposit to date. <a href="#more-davidson" data-toggle="collapse" aria-expanded="false" aria-controls="more-davidson" class="collapsed">Read more <b class="caret"></b></a></p> <div class="collapse" id="more-davidson"> <p><a href="/fluorescent-proteins/davidson/">The Davidson FP deposit</a> includes a comprehensive collection of ORFs tagged with a variety of fluorescent proteins, as well as 295 empty backbones. </p> </div> </div> </div> </li> <li class="timeline-item"> <div class="panel panel-info timeline-panel"> <div class="panel-heading"> <h4 class="panel-title">500,000 Plasmids Distributed <p class="pull-right"><small class="text-muted">March 2015</small></p> </h4> </div> <div class="panel-body"> <p>As of March 20, 2015, Addgene has distributed 500,000 plasmids to researchers around the globe. <a href="#more-distribute" data-toggle="collapse" aria-expanded="false" aria-controls="more-distribute" class="collapsed">Read more <b class="caret"></b></a></p> <div class="collapse" id="more-distribute"> <p>This half-million milestone highlights the major impact that Addgene's plasmid repository has had on the research community in the last decade. We continue to strive to fulfill our mission of facilitating material sharing for scientists. </p> </div> </div> </div> </li> </ul> <ul class="timeline"> <li class="timeline-item"> <div class="panel panel-info timeline-panel"> <div class="panel-heading"> <h4 class="panel-title">Blog Views Reach 50,000 per Month <p class="pull-right"><small class="text-muted">February 2016</small></p> </h4> </div> <div class="panel-body"> <p>The Addgene blog was started in 2013 with the goal of making it easier for members of the Addgene community to share scientific information, learn how to use the latest plasmid technologies, and get tips for career development. <a href="#more-blog" data-toggle="collapse" aria-expanded="false" aria-controls="more-blog" class="collapsed">Read more <b class="caret"></b></a></p> <div class="collapse" id="more-blog"> <p>With consistent content, frequent updating, and writers from all over the world, the blog continues to grow rapidly and is now a valuable educational resource to biology researchers of all levels. <a href="http://info.addgene.org/subscribe-to-addgene-blog" target="_blank" rel="noopener noreferrer">Subscribe</a> or <a href="http://info.addgene.org/sign-up-to-write-for-addgenes-blog" target="_blank" rel="noopener noreferrer">sign up</a> to write with us to help expand this fantastic resource. </p> </div> </div> </div> </li> <li class="timeline-item"> <div class="panel panel-info timeline-panel"> <div class="panel-heading"> <h4 class="panel-title">Inaugural Blue Flame Awards <p class="pull-right"><small class="text-muted">June 2016</small></p> </h4> </div> <div class="panel-body"> <p>The Blue Flame Award serves to congratulate researchers who have at least one plasmid deposited at Addgene that has been distributed more than 100 times. <a href="#more-flame" data-toggle="collapse" aria-expanded="false" aria-controls="more-flame" class="collapsed">Read more <b class="caret"></b></a></p> <div class="collapse" id="more-flame"> <p>We鈥檙e proud to honor the creativity, passion, and dedication to sharing epitomized by the creators of these plasmids with the Blue Flame Awards. View the full list of Addgene鈥檚 <a href="/blue-flame-award/">Blue Flame Awardees here</a>.</p> </div> </div> </div> </li> </ul> <ul class="timeline"> <li class="timeline-item"> <div class="panel panel-info timeline-panel"> <div class="panel-heading"> <h4 class="panel-title">Viral Service Launched <p class="pull-right"><small class="text-muted">July 2016</small></p> </h4> </div> <div class="panel-body"> <p>On July 14, 2016, Addgene began distributing ready-to-use viral preparations for popular plasmids in our repository. <a href="#more-virus" data-toggle="collapse" aria-expanded="false" aria-controls="more-virus" class="collapsed">Read more <b class="caret"></b></a></p> <div class="collapse" id="more-virus"> <p>Many researchers perform the arduous task of producing virus using plasmids from Addgene. To expedite this process and make scientists' lives easier, Addgene has begun producing <a href="/viral-service/">ready-to-use viral preparations</a> from some of our most popular lentiviral and AAV vectors. Addgene hopes that this new service will further accelerate research for scientists worldwide. </p> </div> </div> </div> </li> <li class="timeline-item"> <div class="panel panel-info timeline-panel"> <div class="panel-heading"> <h4 class="panel-title">50,000 Plasmids Available <p class="pull-right"><small class="text-muted">September 2016</small></p> </h4> </div> <div class="panel-body"> <p>As of September 20, 2016, Addgene has 50,000 unique plasmids available through our online repository. <br> <a href="#more-available2" data-toggle="collapse" aria-expanded="false" aria-controls="more-available2" class="collapsed">Read more <b class="caret"></b></a></p> <div class="collapse" id="more-available2"> <p>While Addgene started with plasmids that were primarily used in mammalian work, the repository has expanded greatly and now includes many different collections with tools that can be used in flies, frogs, bacteria, and much more!</p><p>Addgene is proud to be a trusted resource for thousands of scientists worldwide who rely on access to a large variety of plasmids, thorough quality control, fast shipment, and useful educational resources. </p> </div> </div> </div> </li> </ul> <ul class="timeline"> <li class="timeline-item"> <div class="panel panel-info timeline-panel"> <div class="panel-heading"> <h4 class="panel-title">CRISPR 101 eBook Downloaded 20,000x <p class="pull-right"><small class="text-muted">May 2017</small></p> </h4> </div> <div class="panel-body"> <p>We set out to create a consolidated CRISPR educational resource that budding genome engineers could use to get their experiments started. The result was the CRISPR 101 eBook. <a href="#more-ebook" data-toggle="collapse" aria-expanded="false" aria-controls="more-ebook" class="collapsed">Read more <b class="caret"></b></a></p> <div class="collapse" id="more-ebook"> <p>As one of our most widely distributed plasmid technologies, CRISPR generates many thoughtful questions for our Addgene scientists and our CRISPR blog posts are always among our most popular. From the basic biology of CRISPR to therapeutic applications, the CRISPR 101 eBook introduces readers to the many research possibilities enabled by CRISPR. Get your own <a href="http://info.addgene.org/download-addgenes-ebook-crispr-101-2nd-edition" target="_blank" rel="noopener noreferrer">free copy here</a>. </p> </div> </div> </div> </li> <li class="timeline-item"> <div class="panel panel-info timeline-panel"> <div class="panel-heading"> <h4 class="panel-title">1,000 Viral Orders Shipped <p class="pull-right"><small class="text-muted">June 2017</small></p> </h4> </div> <div class="panel-body"> <p>As of June 19, 2017, Addgene has distributed 1,000 ready-to-use viral preparations of plasmids to researchers around the globe. </p> </div> </div> </li> </ul> </div> <hr> <!-- Support Section --> <section id="support"> <h2 class="section-title">Our Nonprofit</h2> <p>Addgene is a <a href="http://blog.addgene.org/addgenes-a-nonprofit-nonprofit-awareness-day-2017" target="_blank" rel="noopener noreferrer">nonprofit</a> 501(c)(3) organization. Fees collected from plasmid requests are used to support the operation of the repository. 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