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ionizing dose</title> <meta name="description" content="Search results for: total ionizing dose"> <meta name="keywords" content="total ionizing dose"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="total ionizing dose"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 10043</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: total ionizing dose</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10043</span> Investigation of Factors Affecting the Total Ionizing Dose Threshold of Electrically Erasable Read Only Memories for Use in Dose Rate Measurement</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Liqian%20Li">Liqian Li</a>, <a href="https://publications.waset.org/abstracts/search?q=Yu%20Liu"> Yu Liu</a>, <a href="https://publications.waset.org/abstracts/search?q=Karen%20Colins"> Karen Colins</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The dose rate present in a seriously contaminated area can be indirectly determined by monitoring radiation damage to inexpensive commercial electronics, instead of deploying expensive radiation hardened sensors. EEPROMs (Electrically Erasable Read Only Memories) are a good candidate for this purpose because they are inexpensive and are sensitive to radiation exposure. When the total ionizing dose threshold is reached, an EEPROM chip will show signs of damage that can be monitored and transmitted by less susceptible electronics. The dose rate can then be determined from the known threshold dose and the exposure time, assuming the radiation field remains constant with time. Therefore, the threshold dose needs to be well understood before this method can be used. There are many factors affecting the threshold dose, such as the gamma ray energy spectrum, the operating voltage, etc. The purpose of this study was to experimentally determine how the threshold dose depends on dose rate, temperature, voltage, and duty factor. It was found that the duty factor has the strongest effect on the total ionizing dose threshold, while the effect of the other three factors that were investigated is less significant. The effect of temperature was found to be opposite to that expected to result from annealing and is yet to be understood. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=EEPROM" title="EEPROM">EEPROM</a>, <a href="https://publications.waset.org/abstracts/search?q=ionizing%20radiation" title=" ionizing radiation"> ionizing radiation</a>, <a href="https://publications.waset.org/abstracts/search?q=radiation%20effects%20on%20electronics" title=" radiation effects on electronics"> radiation effects on electronics</a>, <a href="https://publications.waset.org/abstracts/search?q=total%20ionizing%20dose" title=" total ionizing dose"> total ionizing dose</a>, <a href="https://publications.waset.org/abstracts/search?q=wireless%20sensor%20networks" title=" wireless sensor networks"> wireless sensor networks</a> </p> <a href="https://publications.waset.org/abstracts/77107/investigation-of-factors-affecting-the-total-ionizing-dose-threshold-of-electrically-erasable-read-only-memories-for-use-in-dose-rate-measurement" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/77107.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">184</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10042</span> Protective Effect of Herniarin on Ionizing Radiation-Induced Impairments in Brain</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sophio%20Kalmakhelidze">Sophio Kalmakhelidze</a>, <a href="https://publications.waset.org/abstracts/search?q=Eka%20Shekiladze"> Eka Shekiladze</a>, <a href="https://publications.waset.org/abstracts/search?q=Tamar%20Sanikidze"> Tamar Sanikidze</a>, <a href="https://publications.waset.org/abstracts/search?q=Mikheil%20Gogebashvili"> Mikheil Gogebashvili</a>, <a href="https://publications.waset.org/abstracts/search?q=Nazi%20Ivanishvili"> Nazi Ivanishvili</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Radiation-induced various degrees of brain injury and cognitive impairment have been described after cranial radiotherapy of brain tumors. High doses of ionizing radiation have a severe impact on the central nervous system, resulting in morphological and behavioral impairments. Structures of the limbic system are especially sensitive to radiation exposure. Hence, compounds or drugs that can reduce radiation-induced impairments can be used as promising antioxidants or radioprotectors. In our study Mice whole-body irradiation with 137Cs was performed at a dose rate of 1,1 Gy/min for a total dose of 5 Gy with a “Gamma-capsule-2”. Irradiated mice were treated with Herniarin (20 mg/kg) for five days before irradiation and the same dose was administrated after one hour of irradiation. The immediate and delayed effects of ionizing radiation, as well as, protective effect of Herniarin was evaluated during early and late post-irradiation periods. The results reveal that ionizing radiation (5 Gy) alters the structure of the hippocampus in adult mice during the late post-irradiation period resulting in the decline of memory formation and learning process. Furthermore, Simple Coumarin-Herniarin reveals a radiosensitizing effect reducing morphological and behavioral alterations. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ionizing%20radiation" title="ionizing radiation">ionizing radiation</a>, <a href="https://publications.waset.org/abstracts/search?q=cognitive%20impairments" title=" cognitive impairments"> cognitive impairments</a>, <a href="https://publications.waset.org/abstracts/search?q=hippocampus" title=" hippocampus"> hippocampus</a>, <a href="https://publications.waset.org/abstracts/search?q=limbic%20system" title=" limbic system"> limbic system</a>, <a href="https://publications.waset.org/abstracts/search?q=Herniarin" title=" Herniarin"> Herniarin</a> </p> <a href="https://publications.waset.org/abstracts/176790/protective-effect-of-herniarin-on-ionizing-radiation-induced-impairments-in-brain" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/176790.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">73</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10041</span> Occupational Cumulative Effective Doses of Radiation Workers in Hamad Medical Corporation in Qatar</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Omar%20Bobes">Omar Bobes</a>, <a href="https://publications.waset.org/abstracts/search?q=Abeer%20Al-Attar"> Abeer Al-Attar</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Hassan%20Kharita"> Mohammad Hassan Kharita</a>, <a href="https://publications.waset.org/abstracts/search?q=Huda%20Al-Naemi"> Huda Al-Naemi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The number of radiological examinations has increased steadily in recent years. As a result, the risk of possible radiation-induced consequential damage also increases through continuous, lifelong, and increasing exposure to ionizing radiation. Therefore, radiation dose monitoring in medicine became an essential element of medical practice. In this study, the occupational cumulative doses for radiation workers in Hamad medical corporation in Qatar have been assessed for a period of five years. The number of monitored workers selected for this study was 555 (out of a total of 1250 monitored workers) who have been working continuously -with no interruption- with ionizing radiation over the past five years from 2015 to 2019. The aim of this work is to examine the occupational groups and the activities where the higher radiation exposure occurred and in what order of magnitude. The most exposed group was the nuclear medicine technologist staff, with an average cumulative dose of 8.4 mSv. The highest individual cumulative dose was 9.8 mSv recorded for the PET-CT technologist category. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cumulative%20dose" title="cumulative dose">cumulative dose</a>, <a href="https://publications.waset.org/abstracts/search?q=effective%20dose" title=" effective dose"> effective dose</a>, <a href="https://publications.waset.org/abstracts/search?q=monitoring" title=" monitoring"> monitoring</a>, <a href="https://publications.waset.org/abstracts/search?q=occupational%20exposure" title=" occupational exposure"> occupational exposure</a>, <a href="https://publications.waset.org/abstracts/search?q=dosimetry" title=" dosimetry"> dosimetry</a> </p> <a href="https://publications.waset.org/abstracts/133495/occupational-cumulative-effective-doses-of-radiation-workers-in-hamad-medical-corporation-in-qatar" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/133495.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">243</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10040</span> Mutagenesis, Oxidative Stress Induction and Blood Cytokine Profile in First Generation Male Rats Whose Parents Were Exposed to Radiation and Hexavalent Chromium</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yerbolat%20Iztleuov">Yerbolat Iztleuov</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Stochastic effects, which are currently largely associated with exposure to ionizing radiation or a combination of ionizing radiation with other chemical, physical, and biological agents, are expressed in the form of various mutations. In the first stage of the study, rats of both sexes were divided into 3 groups. 1st - control group, animals of the 2nd group were exposed to gamma radiation at a dose of 0.2 Gy. The third group received hexavalent chromium in a dose of 180 mg/ l with drinking water for a month before irradiation and a day after the end of chromium consumption and was subjected to total gamma irradiation at a dose of 0.2 Gy. The second stage of the experiment. After 3 days, the males were mated with the females. The obtained offspring were studied for peroxidation, cytokine profile and micronucleus in the nuclei. This study shows that 5-month-old offspring whose parents were exposed to combined exposure to chromium and γ-irradiation exhibit hereditary instability of the genome, decreased activity of antioxidant enzymes and sulfhydryl blood groups, and increased levels of lipid peroxidation. There is also an increase in the level of inflammatory markers (IL-6 and TNF) in the blood plasma against the background of a decrease in anti-inflammatory cytokine (IL-10). Thus, the combined effect of hexavalent chromium and ionizing radiation can lead to the development of an oncological process. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hexavalent%20chromium" title="hexavalent chromium">hexavalent chromium</a>, <a href="https://publications.waset.org/abstracts/search?q=ionizing%20radiation" title=" ionizing radiation"> ionizing radiation</a>, <a href="https://publications.waset.org/abstracts/search?q=first%20generation" title=" first generation"> first generation</a>, <a href="https://publications.waset.org/abstracts/search?q=oxidative%20stress" title=" oxidative stress"> oxidative stress</a>, <a href="https://publications.waset.org/abstracts/search?q=cytokines" title=" cytokines"> cytokines</a>, <a href="https://publications.waset.org/abstracts/search?q=mutagenesis" title=" mutagenesis"> mutagenesis</a>, <a href="https://publications.waset.org/abstracts/search?q=cancer" title=" cancer"> cancer</a> </p> <a href="https://publications.waset.org/abstracts/190168/mutagenesis-oxidative-stress-induction-and-blood-cytokine-profile-in-first-generation-male-rats-whose-parents-were-exposed-to-radiation-and-hexavalent-chromium" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/190168.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">28</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10039</span> Vertebrate Model to Examine the Biological Effectiveness of Different Radiation Qualities</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rita%20Em%C3%ADlia%20Szab%C3%B3">Rita Emília Szabó</a>, <a href="https://publications.waset.org/abstracts/search?q=R%C3%B3bert%20Polanek"> Róbert Polanek</a>, <a href="https://publications.waset.org/abstracts/search?q=T%C3%BCnde%20T%C5%91k%C3%A9s"> Tünde Tőkés</a>, <a href="https://publications.waset.org/abstracts/search?q=Zolt%C3%A1n%20Szab%C3%B3"> Zoltán Szabó</a>, <a href="https://publications.waset.org/abstracts/search?q=Szabolcs%20Czifrus"> Szabolcs Czifrus</a>, <a href="https://publications.waset.org/abstracts/search?q=Katalin%20Hidegh%C3%A9ty"> Katalin Hideghéty</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: Several feature of zebrafish are making them amenable for investigation on therapeutic approaches such as ionizing radiation. The establishment of zebrafish model for comprehensive radiobiological research stands in the focus of our investigation, comparing the radiation effect curves of neutron and photon irradiation. Our final aim is to develop an appropriate vertebrate model in order to investigate the relative biological effectiveness of laser driven ionizing radiation. Methods and Materials: After careful dosimetry series of viable zebrafish embryos were exposed to a single fraction whole-body neutron-irradiation (1,25; 1,875; 2; 2,5 Gy) at the research reactor of the Technical University of Budapest and to conventional 6 MeV photon beam at 24 hour post-fertilization (hpf). The survival and morphologic abnormalities (pericardial edema, spine curvature) of each embryo were assessed for each experiment at 24-hour intervals from the point of fertilization up to 168 hpf (defining the dose lethal for 50% (LD50)). Results: In the zebrafish embryo model LD50 at 20 Gy dose level was defined and the same lethality were found at 2 Gy dose from the reactor neutron beam resulting RBE of 10. Dose-dependent organ perturbations were detected on macroscopic (shortening of the body length, spine curvature, microcephaly, micro-ophthalmia, micrognathia, pericardial edema, and inhibition of yolk sac resorption) and microscopic (marked cellular changes in skin, cardiac, gastrointestinal system) with the same magnitude of dose difference. Conclusion: In our observations, we found that zebrafish embryo model can be used for investigating the effects of different type of ionizing radiation and this system proved to be highly efficient vertebrate model for preclinical examinations. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ionizing%20radiation" title="ionizing radiation">ionizing radiation</a>, <a href="https://publications.waset.org/abstracts/search?q=LD50" title=" LD50"> LD50</a>, <a href="https://publications.waset.org/abstracts/search?q=relative%20biological%20effectiveness" title=" relative biological effectiveness"> relative biological effectiveness</a>, <a href="https://publications.waset.org/abstracts/search?q=zebrafish%20embryo" title=" zebrafish embryo"> zebrafish embryo</a> </p> <a href="https://publications.waset.org/abstracts/42445/vertebrate-model-to-examine-the-biological-effectiveness-of-different-radiation-qualities" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/42445.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">309</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10038</span> Thermal Analysis of a Graphite Calorimeter for the Measurement of Absorbed Dose for Therapeutic X-Ray Beam</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=I.J.%20Kim">I.J. Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=B.C.%20Kim"> B.C. Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=J.H.%20Kim"> J.H. Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=C.-Y.%20Yi"> C.-Y. Yi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Heat transfer in a graphite calorimeter is analyzed by using the finite elements method. The calorimeter is modeled in 3D geometry. Quasi-adiabatic mode operation is realized in the simulation and the temperature rise by different sources of the ionizing radiation and electric heaters is compared, directly. The temperature distribution caused by the electric power was much different from that by the ionizing radiation because of its point-like localized heating. However, the temperature rise which was finally read by sensing thermistors agreed well to each other within 0.02 %. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=graphite%20calorimeter" title="graphite calorimeter">graphite calorimeter</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20analysis" title=" finite element analysis"> finite element analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=heat%20transfer" title=" heat transfer"> heat transfer</a>, <a href="https://publications.waset.org/abstracts/search?q=quasi-adiabatic%20mode" title=" quasi-adiabatic mode "> quasi-adiabatic mode </a> </p> <a href="https://publications.waset.org/abstracts/24560/thermal-analysis-of-a-graphite-calorimeter-for-the-measurement-of-absorbed-dose-for-therapeutic-x-ray-beam" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/24560.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">430</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10037</span> Comparative Study of Dose Calculation Accuracy in Bone Marrow Using Monte Carlo Method</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Marzieh%20Jafarzadeh">Marzieh Jafarzadeh</a>, <a href="https://publications.waset.org/abstracts/search?q=Fatemeh%20Rezaee"> Fatemeh Rezaee</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: The effect of ionizing radiation on human health can be effective for genomic integrity and cell viability. It also increases the risk of cancer and malignancy. Therefore, X-ray behavior and absorption dose calculation are considered. One of the applicable tools for calculating and evaluating the absorption dose in human tissues is Monte Carlo simulation. Monte Carlo offers a straightforward way to simulate and integrate, and because it is simple and straightforward, Monte Carlo is easy to use. The Monte Carlo BEAMnrc code is one of the most common diagnostic X-ray simulation codes used in this study. Method: In one of the understudy hospitals, a certain number of CT scan images of patients who had previously been imaged were extracted from the hospital database. BEAMnrc software was used for simulation. The simulation of the head of the device with the energy of 0.09 MeV with 500 million particles was performed, and the output data obtained from the simulation was applied for phantom construction using CT CREATE software. The percentage of depth dose (PDD) was calculated using STATE DOSE was then compared with international standard values. Results and Discussion: The ratio of surface dose to depth dose (D/Ds) in the measured energy was estimated to be about 4% to 8% for bone and 3% to 7% for bone marrow. Conclusion: MC simulation is an efficient and accurate method for simulating bone marrow and calculating the absorbed dose. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Monte%20Carlo" title="Monte Carlo">Monte Carlo</a>, <a href="https://publications.waset.org/abstracts/search?q=absorption%20dose" title=" absorption dose"> absorption dose</a>, <a href="https://publications.waset.org/abstracts/search?q=BEAMnrc" title=" BEAMnrc"> BEAMnrc</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20marrow" title=" bone marrow"> bone marrow</a> </p> <a href="https://publications.waset.org/abstracts/135306/comparative-study-of-dose-calculation-accuracy-in-bone-marrow-using-monte-carlo-method" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/135306.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">213</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10036</span> Assessment of Occupational Exposure and Individual Radio-Sensitivity in People Subjected to Ionizing Radiation </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Oksana%20G.%20Cherednichenko">Oksana G. Cherednichenko</a>, <a href="https://publications.waset.org/abstracts/search?q=Anastasia%20L.%20Pilyugina"> Anastasia L. Pilyugina</a>, <a href="https://publications.waset.org/abstracts/search?q=Sergey%20N.Lukashenko"> Sergey N.Lukashenko</a>, <a href="https://publications.waset.org/abstracts/search?q=Elena%20G.%20Gubitskaya"> Elena G. Gubitskaya</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The estimation of accumulated radiation doses in people professionally exposed to ionizing radiation was performed using methods of biological (chromosomal aberrations frequency in lymphocytes) and physical (radionuclides analysis in urine, whole-body radiation meter, individual thermoluminescent dosimeters) dosimetry. A group of 84 "A" category employees after their work in the territory of former Semipalatinsk test site (Kazakhstan) was investigated. The dose rate in some funnels exceeds 40 μSv/h. After radionuclides determination in urine using radiochemical and WBC methods, it was shown that the total effective dose of personnel internal exposure did not exceed 0.2 mSv/year, while an acceptable dose limit for staff is 20 mSv/year. The range of external radiation doses measured with individual thermo-luminescent dosimeters was 0.3-1.406 µSv. The cytogenetic examination showed that chromosomal aberrations frequency in staff was 4.27±0.22%, which is significantly higher than at the people from non-polluting settlement Tausugur (0.87±0.1%) (р ≤ 0.01) and citizens of Almaty (1.6±0.12%) (р≤ 0.01). Chromosomal type aberrations accounted for 2.32±0.16%, 0.27±0.06% of which were dicentrics and centric rings. The cytogenetic analysis of different types group radiosensitivity among «professionals» (age, sex, ethnic group, epidemiological data) revealed no significant differences between the compared values. Using various techniques by frequency of dicentrics and centric rings, the average cumulative radiation dose for group was calculated, and that was 0.084-0.143 Gy. To perform comparative individual dosimetry using physical and biological methods of dose assessment, calibration curves (including own ones) and regression equations based on general frequency of chromosomal aberrations obtained after irradiation of blood samples by gamma-radiation with the dose rate of 0,1 Gy/min were used. Herewith, on the assumption of individual variation of chromosomal aberrations frequency (1–10%), the accumulated dose of radiation varied 0-0.3 Gy. The main problem in the interpretation of individual dosimetry results is reduced to different reaction of the objects to irradiation - radiosensitivity, which dictates the need of quantitative definition of this individual reaction and its consideration in the calculation of the received radiation dose. The entire examined contingent was assigned to a group based on the received dose and detected cytogenetic aberrations. Radiosensitive individuals, at the lowest received dose in a year, showed the highest frequency of chromosomal aberrations (5.72%). In opposite, radioresistant individuals showed the lowest frequency of chromosomal aberrations (2.8%). The cohort correlation according to the criterion of radio-sensitivity in our research was distributed as follows: radio-sensitive (26.2%) — medium radio-sensitivity (57.1%), radioresistant (16.7%). Herewith, the dispersion for radioresistant individuals is 2.3; for the group with medium radio-sensitivity — 3.3; and for radio-sensitive group — 9. These data indicate the highest variation of characteristic (reactions to radiation effect) in the group of radio-sensitive individuals. People with medium radio-sensitivity show significant long-term correlation (0.66; n=48, β ≥ 0.999) between the values of doses defined according to the results of cytogenetic analysis and dose of external radiation obtained with the help of thermoluminescent dosimeters. Mathematical models based on the type of violation of the radiation dose according to the professionals radiosensitivity level were offered. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biodosimetry" title="biodosimetry">biodosimetry</a>, <a href="https://publications.waset.org/abstracts/search?q=chromosomal%20aberrations" title=" chromosomal aberrations"> chromosomal aberrations</a>, <a href="https://publications.waset.org/abstracts/search?q=ionizing%20radiation" title=" ionizing radiation"> ionizing radiation</a>, <a href="https://publications.waset.org/abstracts/search?q=radiosensitivity" title=" radiosensitivity"> radiosensitivity</a> </p> <a href="https://publications.waset.org/abstracts/74455/assessment-of-occupational-exposure-and-individual-radio-sensitivity-in-people-subjected-to-ionizing-radiation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/74455.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">184</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10035</span> Using SNAP and RADTRAD to Establish the Analysis Model for Maanshan PWR Plant</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=J.%20R.%20Wang">J. R. Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20C.%20Chen"> H. C. Chen</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Shih"> C. Shih</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20W.%20Chen"> S. W. Chen</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20H.%20Yang"> J. H. Yang</a>, <a href="https://publications.waset.org/abstracts/search?q=Y.%20Chiang"> Y. Chiang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, we focus on the establishment of the analysis model for Maanshan PWR nuclear power plant (NPP) by using RADTRAD and SNAP codes with the FSAR, manuals, and other data. In order to evaluate the cumulative dose at the Exclusion Area Boundary (EAB) and Low Population Zone (LPZ) outer boundary, Maanshan NPP RADTRAD/SNAP model was used to perform the analysis of the DBA LOCA case. The analysis results of RADTRAD were similar to FSAR data. These analysis results were lower than the failure criteria of 10 CFR 100.11 (a total radiation dose to the whole body, 250 mSv; a total radiation dose to the thyroid from iodine exposure, 3000 mSv). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=RADionuclide" title="RADionuclide">RADionuclide</a>, <a href="https://publications.waset.org/abstracts/search?q=transport" title=" transport"> transport</a>, <a href="https://publications.waset.org/abstracts/search?q=removal" title=" removal"> removal</a>, <a href="https://publications.waset.org/abstracts/search?q=and%20dose%20estimation%20%28RADTRAD%29" title=" and dose estimation (RADTRAD)"> and dose estimation (RADTRAD)</a>, <a href="https://publications.waset.org/abstracts/search?q=symbolic%20nuclear%20analysis%20package%20%28SNAP%29" title=" symbolic nuclear analysis package (SNAP)"> symbolic nuclear analysis package (SNAP)</a>, <a href="https://publications.waset.org/abstracts/search?q=dose" title=" dose"> dose</a>, <a href="https://publications.waset.org/abstracts/search?q=PWR" title=" PWR"> PWR</a> </p> <a href="https://publications.waset.org/abstracts/73319/using-snap-and-radtrad-to-establish-the-analysis-model-for-maanshan-pwr-plant" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/73319.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">464</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10034</span> Evaluation of the Gamma-H2AX Expression as a Biomarker of DNA Damage after X-Ray Radiation in Angiography Patients</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Reza%20Fardid">Reza Fardid</a>, <a href="https://publications.waset.org/abstracts/search?q=Aliyeh%20Alipour"> Aliyeh Alipour</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Coronary heart disease (CHD) is the most common and deadliest diseases. A coronary angiography is an important tool for the diagnosis and treatment of this disease. Because angiography is performed by exposure to ionizing radiation, it can lead to harmful effects. Ionizing radiation induces double-stranded breaks in DNA, which is a potentially life-threatening injury. The purpose of the present study is an investigation of the phosphorylation of histone H2AX in the location of the double-stranded break in Peripheral blood lymphocytes as an indication of Biological effects of radiation on angiography patients. Materials and Methods: This method is based on measurement of the phosphorylation of histone (gamma-H2AX, gH2AX) level on serine 139 after formation of DNA double-strand break. 5 cc of blood from 24 patients with angiography were sampled before and after irradiation. Blood lymphocytes were removed, fixed and were stained with specific ϒH2AX antibodies. Finally, ϒH2AX signal as an indicator of the double-strand break was measured with Flow Cytometry Technique. Results and discussion: In all patients, an increase was observed in the number of breaks in double-stranded DNA after irradiation (20.15 ± 14.18) compared to before exposure (1.52 ± 0.34). Also, the mean of DNA double-strand break was showed a linear correlation with DAP. However, although induction of DNA double-strand breaks associated with radiation dose in patients, the effect of individual factors such as radiosensitivity and regenerative capacity should not be ignored. If in future we can measure DNA damage response in every patient angiography and it will be used as a biomarker patient dose, will look very impressive on the public health level. Conclusion: Using flow cytometry readings which are done automatically, it is possible to detect ϒH2AX in the number of blood cells. Therefore, the use of this technique could play a significant role in monitoring patients. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=coronary%20angiography" title="coronary angiography">coronary angiography</a>, <a href="https://publications.waset.org/abstracts/search?q=DSB%20of%20DNA" title=" DSB of DNA"> DSB of DNA</a>, <a href="https://publications.waset.org/abstracts/search?q=%CF%92H2AX" title=" ϒH2AX"> ϒH2AX</a>, <a href="https://publications.waset.org/abstracts/search?q=ionizing%20radiation" title=" ionizing radiation"> ionizing radiation</a> </p> <a href="https://publications.waset.org/abstracts/66700/evaluation-of-the-gamma-h2ax-expression-as-a-biomarker-of-dna-damage-after-x-ray-radiation-in-angiography-patients" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/66700.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">184</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10033</span> Experimental and Analytical Dose Assessment of Patient's Family Members Treated with I-131</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Marzieh%20Ebrahimi">Marzieh Ebrahimi</a>, <a href="https://publications.waset.org/abstracts/search?q=Vahid%20Changizi"> Vahid Changizi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Reza%20Kardan"> Mohammad Reza Kardan</a>, <a href="https://publications.waset.org/abstracts/search?q=Seyed%20Mahdi%20Hosseini%20Pooya"> Seyed Mahdi Hosseini Pooya</a>, <a href="https://publications.waset.org/abstracts/search?q=Parham%20Geramifar"> Parham Geramifar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Radiation exposure to the patient's family members is one of the major concerns during thyroid cancer radionuclide therapy. The aim of this study was to measure the total effective dose of the family members by means of thermoluminescence personal dosimeter, and compare with those calculated by analytical methods. Eighty-five adult family members of fifty-one patients volunteered to participate in this research study. Considering the minimum and maximum range of dose rate from 15 µsv/h to 120 µsv/h at patients' release time, the calculated mean and median dose values of family members were 0.45 mSv and 0.28 mSv, respectively. Moreover, almost all family members’ doses were measured to be less than the dose constraint of 5 mSv recommended by Basic Safety Standards. Considering the influence parameters such as patient dose rate and administrated activity, the total effective doses of family members were calculated by TEDE and NRC formulas and compared with those of experimental results. The results indicated that, it is fruitful to use the quantitative calculations for releasing patients treated with I-131 and correct estimation of patients' family doses. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=effective%20dose" title="effective dose">effective dose</a>, <a href="https://publications.waset.org/abstracts/search?q=thermoluminescence" title=" thermoluminescence"> thermoluminescence</a>, <a href="https://publications.waset.org/abstracts/search?q=I-131" title=" I-131"> I-131</a>, <a href="https://publications.waset.org/abstracts/search?q=thyroid%20cancer" title=" thyroid cancer"> thyroid cancer</a> </p> <a href="https://publications.waset.org/abstracts/50786/experimental-and-analytical-dose-assessment-of-patients-family-members-treated-with-i-131" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/50786.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">400</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10032</span> Assessment of Radiological Dose for Th-232 Laboratory Accumulated in Tropical Freshwater Fish</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zal%20U%E2%80%99yun%20Wan%20Mahmood">Zal U’yun Wan Mahmood</a>, <a href="https://publications.waset.org/abstracts/search?q=Norfaizal%20Mohamed"> Norfaizal Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Nita%20Salina%20Abu%20Bakar"> Nita Salina Abu Bakar</a>, <a href="https://publications.waset.org/abstracts/search?q=Yii%20Mei%20Wo"> Yii Mei Wo</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdul%20Kadir%20Ishak"> Abdul Kadir Ishak</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamad%20Noh%20Sawon"> Mohamad Noh Sawon</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohd%20Tarmizi%20Ishak"> Mohd Tarmizi Ishak</a>, <a href="https://publications.waset.org/abstracts/search?q=Khairul%20Nizam%20Razali"> Khairul Nizam Razali</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The study of thorium radiotracer bioaccumulation in the whole body tropical freshwater fish (Anabas testudeneus; climb pearch) was performed. The objective of this study was to evaluate the effect of different Th-232 activity concentration andradiological dose in Anabas testudeneus under the laboratory bioaccumulation condition. Anabas testudeneus adults were exposed to different waterborne Th-232 levels: 0 BqL-1 (control), 50 BqL-1, 100 BqL-1,150 BqL-1and 200 BqL-1for 30 days. Radionuclide concentration ratios between the whole body levels and water levels were calculated and; total dose rates and risk quotients using ERICA Assessment Tool were also estimated. The results showed the increase of waterborne Th-232 concentration corresponded to a progressive decrease of Th concentration ratio. Meanwhile, the total dose rate (internal and external) in the whole body of Anabas testudeneus less than the ERICA dose rate screening value of 10 µGyh-1 and the risk quotient less than one. Thus, the findings can be concluded that the radiological dose of Th-232 to Anabas testudeneus is a very low probability and the situation may be considered to be of negligible radiological concern. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anabas%20testudeneus" title="Anabas testudeneus">Anabas testudeneus</a>, <a href="https://publications.waset.org/abstracts/search?q=bioaccumulation" title=" bioaccumulation"> bioaccumulation</a>, <a href="https://publications.waset.org/abstracts/search?q=radiological%20dose" title=" radiological dose"> radiological dose</a>, <a href="https://publications.waset.org/abstracts/search?q=Th-232" title=" Th-232"> Th-232</a> </p> <a href="https://publications.waset.org/abstracts/27965/assessment-of-radiological-dose-for-th-232-laboratory-accumulated-in-tropical-freshwater-fish" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/27965.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">325</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10031</span> The Use of the Matlab Software as the Best Way to Recognize Penumbra Region in Radiotherapy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Alireza%20Shayegan">Alireza Shayegan</a>, <a href="https://publications.waset.org/abstracts/search?q=Morteza%20Amirabadi"> Morteza Amirabadi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The y tool was developed to quantitatively compare dose distributions, either measured or calculated. Before computing ɣ, the dose and distance scales of the two distributions, referred to as evaluated and reference, are re-normalized by dose and distance criteria, respectively. The re-normalization allows the dose distribution comparison to be conducted simultaneously along dose and distance axes. Several two-dimensional images were acquired using a Scanning Liquid Ionization Chamber EPID and Extended Dose Range (EDR2) films for regular and irregular radiation fields. The raw images were then converted into two-dimensional dose maps. Transitional and rotational manipulations were performed for images using Matlab software. As evaluated dose distribution maps, they were then compared with the corresponding original dose maps as the reference dose maps. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=energetic%20electron" title="energetic electron">energetic electron</a>, <a href="https://publications.waset.org/abstracts/search?q=gamma%20function" title=" gamma function"> gamma function</a>, <a href="https://publications.waset.org/abstracts/search?q=penumbra" title=" penumbra"> penumbra</a>, <a href="https://publications.waset.org/abstracts/search?q=Matlab%20software" title=" Matlab software "> Matlab software </a> </p> <a href="https://publications.waset.org/abstracts/1778/the-use-of-the-matlab-software-as-the-best-way-to-recognize-penumbra-region-in-radiotherapy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/1778.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">301</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10030</span> A Varicella Outbreak in a Highly Vaccinated School Population in Voluntary 2-Dose Era in Beijing, China</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Chengbin%20Wang">Chengbin Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=Li%20Lu"> Li Lu</a>, <a href="https://publications.waset.org/abstracts/search?q=Luodan%20Suo"> Luodan Suo</a>, <a href="https://publications.waset.org/abstracts/search?q=Qinghai%20Wang"> Qinghai Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=Fan%20Yang"> Fan Yang</a>, <a href="https://publications.waset.org/abstracts/search?q=Xu%20Wang"> Xu Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=Mona%20Marin"> Mona Marin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Two-dose varicella vaccination has been recommended in Beijing since November 2012. We investigated a varicella outbreak in a highly vaccinated elementary school population to examine transmission patterns and risk factors for vaccine failure. Methods: A varicella case was defined as an acute generalized maculopapulovesicular rash without other apparent cause in a student attending the school from March 28 to May 17, 2015. Breakthrough varicella was defined as varicella >42 days after last vaccine dose. Vaccination information was collected from immunization records. Information on prior disease and clinical presentation was collected via survey of students’ parents. Results: Of the 1056 school students, 1028 (97.3%) reported no varicella history, of whom 364 (35.4%) had received 1-dose and 650 (63.2%) had received 2-dose varicella vaccine, for 98.6% school-wide vaccination coverage with ≥ 1 dose before the outbreak. A total of 20 cases were identified for an overall attack rate of 1.9%. The index case was in a 2-dose vaccinated student who was not isolated. The majority of cases were breakthrough (19/20, 95%) with attack rates of 7.1% (1/14), 1.6% (6/364) and 2.0% (13/650) among unvaccinated, 1-dose, and 2-dose students, respectively. Most cases had < 50 lesions (18/20, 90%). No difference was found between 1-dose and 2-dose breakthrough cases in disease severity or sociodemographic factors. Conclusion: Moderate 2-dose varicella vaccine coverage was insufficient to prevent a varicella outbreak. Two-dose breakthrough varicella is still contagious. High 2-dose varicella vaccine coverage and timely isolation of ill persons might be needed for varicella outbreak control in the 2-dose era. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=varicella" title="varicella">varicella</a>, <a href="https://publications.waset.org/abstracts/search?q=outbreak" title=" outbreak"> outbreak</a>, <a href="https://publications.waset.org/abstracts/search?q=breakthrough%20varicella" title=" breakthrough varicella"> breakthrough varicella</a>, <a href="https://publications.waset.org/abstracts/search?q=vaccination" title=" vaccination"> vaccination</a> </p> <a href="https://publications.waset.org/abstracts/57932/a-varicella-outbreak-in-a-highly-vaccinated-school-population-in-voluntary-2-dose-era-in-beijing-china" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/57932.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">335</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10029</span> Skin-Dose Mapping for Patients Undergoing Interventional Radiology Procedures: Clinical Experimentations versus a Mathematical Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aya%20Al%20Masri">Aya Al Masri</a>, <a href="https://publications.waset.org/abstracts/search?q=Stefaan%20Carpentier"> Stefaan Carpentier</a>, <a href="https://publications.waset.org/abstracts/search?q=Fabrice%20Leroy"> Fabrice Leroy</a>, <a href="https://publications.waset.org/abstracts/search?q=Thibault%20Julien"> Thibault Julien</a>, <a href="https://publications.waset.org/abstracts/search?q=Safoin%20Aktaou"> Safoin Aktaou</a>, <a href="https://publications.waset.org/abstracts/search?q=Malorie%20Martin"> Malorie Martin</a>, <a href="https://publications.waset.org/abstracts/search?q=Fouad%20Maaloul"> Fouad Maaloul</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: During an 'Interventional Radiology (IR)' procedure, the patient's skin-dose may become very high for a burn, necrosis and ulceration to appear. In order to prevent these deterministic effects, an accurate calculation of the patient skin-dose mapping is essential. For most machines, the 'Dose Area Product (DAP)' and fluoroscopy time are the only information available for the operator. These two parameters are a very poor indicator of the peak skin dose. We developed a mathematical model that reconstructs the magnitude (delivered dose), shape, and localization of each irradiation field on the patient skin. In case of critical dose exceeding, the system generates warning alerts. We present the results of its comparison with clinical studies. Materials and methods: Two series of comparison of the skin-dose mapping of our mathematical model with clinical studies were performed: 1. At a first time, clinical tests were performed on patient phantoms. Gafchromic films were placed on the table of the IR machine under of PMMA plates (thickness = 20 cm) that simulate the patient. After irradiation, the film darkening is proportional to the radiation dose received by the patient's back and reflects the shape of the X-ray field. After film scanning and analysis, the exact dose value can be obtained at each point of the mapping. Four experimentation were performed, constituting a total of 34 acquisition incidences including all possible exposure configurations. 2. At a second time, clinical trials were launched on real patients during real 'Chronic Total Occlusion (CTO)' procedures for a total of 80 cases. Gafchromic films were placed at the back of patients. We performed comparisons on the dose values, as well as the distribution, and the shape of irradiation fields between the skin dose mapping of our mathematical model and Gafchromic films. Results: The comparison between the dose values shows a difference less than 15%. Moreover, our model shows a very good geometric accuracy: all fields have the same shape, size and location (uncertainty < 5%). Conclusion: This study shows that our model is a reliable tool to warn physicians when a high radiation dose is reached. Thus, deterministic effects can be avoided. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=clinical%20experimentation" title="clinical experimentation">clinical experimentation</a>, <a href="https://publications.waset.org/abstracts/search?q=interventional%20radiology" title=" interventional radiology"> interventional radiology</a>, <a href="https://publications.waset.org/abstracts/search?q=mathematical%20model" title=" mathematical model"> mathematical model</a>, <a href="https://publications.waset.org/abstracts/search?q=patient%27s%20skin-dose%20mapping." title=" patient's skin-dose mapping."> patient's skin-dose mapping.</a> </p> <a href="https://publications.waset.org/abstracts/118816/skin-dose-mapping-for-patients-undergoing-interventional-radiology-procedures-clinical-experimentations-versus-a-mathematical-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/118816.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">140</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10028</span> Results of EPR Dosimetry Study of Population Residing in the Vicinity of the Uranium Mines and Uranium Processing Plant</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=K.%20Zhumadilov">K. Zhumadilov</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Kazymbet"> P. Kazymbet</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Ivannikov"> A. Ivannikov</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Bakhtin"> M. Bakhtin</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Akylbekov"> A. Akylbekov</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20Kadyrzhanov"> K. Kadyrzhanov</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Morzabayev"> A. Morzabayev</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Hoshi"> M. Hoshi </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of the study is to evaluate the possible excess of dose received by uranium processing plant workers. The possible excess of dose of workers was evaluated with comparison with population pool (Stepnogorsk) and control pool (Astana city). The measured teeth samples were extracted according to medical indications. In total, twenty-seven tooth enamel samples were analyzed from the residents of Stepnogorsk city (180 km from Astana city, Kazakhstan). About 6 tooth samples were collected from the workers of uranium processing plant. The results of tooth enamel dose estimation show us small influence of working conditions to workers, the maximum excess dose is less than 100 mGy. This is pilot study of EPR dose estimation and for a final conclusion additional sample is required. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=EPR%20dose" title="EPR dose">EPR dose</a>, <a href="https://publications.waset.org/abstracts/search?q=workers" title=" workers"> workers</a>, <a href="https://publications.waset.org/abstracts/search?q=uranium%20mines" title=" uranium mines"> uranium mines</a>, <a href="https://publications.waset.org/abstracts/search?q=tooth%20samples" title=" tooth samples"> tooth samples</a> </p> <a href="https://publications.waset.org/abstracts/2357/results-of-epr-dosimetry-study-of-population-residing-in-the-vicinity-of-the-uranium-mines-and-uranium-processing-plant" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/2357.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">411</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10027</span> Assessment of Radiation Protection Measures in Diagnosis and Treatment: A Critical Review</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Buhari%20Samaila">Buhari Samaila</a>, <a href="https://publications.waset.org/abstracts/search?q=Buhari%20Maidamma"> Buhari Maidamma</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The use of ionizing radiation in medical diagnostics and treatment is indispensable for accurate imaging and effective cancer therapies. However, radiation exposure carries inherent risks, necessitating strict protection measures to safeguard both patients and healthcare workers. This review critically examines the existing radiation protection measures in diagnostic radiology and radiotherapy, highlighting technological advancements, regulatory frameworks, and challenges. Objective: The objective of this review is to critically evaluate the effectiveness of current radiation protection measures in diagnostic and therapeutic radiology, focusing on minimizing patient and staff exposure to ionizing radiation while ensuring optimal clinical outcomes and propose future directions for improvement. Method: A comprehensive literature review was conducted, covering scientific studies, regulatory guidelines, and international standards on radiation protection in both diagnostic radiology and radiotherapy. Emphasis was placed on ALARA principles, dose optimization techniques, and protective measures for both patients and healthcare workers. Results: Radiation protection measures in diagnostic radiology include the use of shielding devices, minimizing exposure times, and employing advanced imaging technologies to reduce dose. In radiotherapy, accurate treatment planning and image-guided techniques enhance patient safety, while shielding and dose monitoring safeguard healthcare personnel. Challenges such as limited infrastructure in low-income settings and gaps in healthcare worker training persist, impacting the overall efficacy of protection strategies. Conclusion: While significant advancements have been made in radiation protection, challenges remain in optimizing safety, especially in resource-limited settings. Future efforts should focus on enhancing training, investing in advanced technologies, and strengthening regulatory compliance to ensure continuous improvement in radiation safety practices. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=radiation%20protection" title="radiation protection">radiation protection</a>, <a href="https://publications.waset.org/abstracts/search?q=diagnostic%20radiology" title=" diagnostic radiology"> diagnostic radiology</a>, <a href="https://publications.waset.org/abstracts/search?q=radiotherapy" title=" radiotherapy"> radiotherapy</a>, <a href="https://publications.waset.org/abstracts/search?q=ALARA" title=" ALARA"> ALARA</a>, <a href="https://publications.waset.org/abstracts/search?q=patient%20safety" title=" patient safety"> patient safety</a>, <a href="https://publications.waset.org/abstracts/search?q=healthcare%20worker%20safety" title=" healthcare worker safety"> healthcare worker safety</a> </p> <a href="https://publications.waset.org/abstracts/192832/assessment-of-radiation-protection-measures-in-diagnosis-and-treatment-a-critical-review" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/192832.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">25</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10026</span> Estimation of Effective Radiation Dose Following Computed Tomography Urography at Aminu Kano Teaching Hospital, Kano Nigeria</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Idris%20Garba">Idris Garba</a>, <a href="https://publications.waset.org/abstracts/search?q=Aisha%20Rabiu%20Abdullahi"> Aisha Rabiu Abdullahi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mansur%20Yahuza"> Mansur Yahuza</a>, <a href="https://publications.waset.org/abstracts/search?q=Akintade%20Dare"> Akintade Dare</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: CT urography (CTU) is efficient radiological examination for the evaluation of the urinary system disorders. However, patients are exposed to a significant radiation dose which is in a way associated with increased cancer risks. Objectives: To determine Computed Tomography Dose Index following CTU, and to evaluate organs equivalent doses. Materials and Methods: A prospective cohort study was carried at a tertiary institution located in Kano northwestern. Ethical clearance was sought and obtained from the research ethics board of the institution. Demographic, scan parameters and CT radiation dose data were obtained from patients that had CTU procedure. Effective dose, organ equivalent doses, and cancer risks were estimated using SPSS statistical software version 16 and CT dose calculator software. Result: A total of 56 patients were included in the study, consisting of 29 males and 27 females. The common indication for CTU examination was found to be renal cyst seen commonly among young adults (15-44yrs). CT radiation dose values in DLP, CTDI and effective dose for CTU were 2320 mGy cm, CTDIw 9.67 mGy and 35.04 mSv respectively. The probability of cancer risks was estimated to be 600 per a million CTU examinations. Conclusion: In this study, the radiation dose for CTU is considered significantly high, with increase in cancer risks probability. Wide radiation dose variations between patient doses suggest that optimization is not fulfilled yet. Patient radiation dose estimate should be taken into consideration when imaging protocols are established for CT urography. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=CT%20urography" title="CT urography">CT urography</a>, <a href="https://publications.waset.org/abstracts/search?q=cancer%20risks" title=" cancer risks"> cancer risks</a>, <a href="https://publications.waset.org/abstracts/search?q=effective%20dose" title=" effective dose"> effective dose</a>, <a href="https://publications.waset.org/abstracts/search?q=radiation%20exposure" title=" radiation exposure"> radiation exposure</a> </p> <a href="https://publications.waset.org/abstracts/61467/estimation-of-effective-radiation-dose-following-computed-tomography-urography-at-aminu-kano-teaching-hospital-kano-nigeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/61467.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">345</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10025</span> Investigation of Threshold Voltage Shift in Gamma Irradiated N-Channel and P-Channel MOS Transistors of CD4007</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20Boorboor">S. Boorboor</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20A.%20H.%20Feghhi"> S. A. H. Feghhi</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Jafari"> H. Jafari</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The ionizing radiations cause different kinds of damages in electronic components. MOSFETs, most common transistors in today’s digital and analog circuits, are severely sensitive to TID damage. In this work, the threshold voltage shift of CD4007 device, which is an integrated circuit including P-channel and N-channel MOS transistors, was investigated for low dose gamma irradiation under different gate bias voltages. We used linear extrapolation method to extract threshold voltage from I<sub>D</sub>-V<sub>G</sub> characteristic curve. The results showed that the threshold voltage shift was approximately 27.5 mV/Gy for N-channel and 3.5 mV/Gy for P-channel transistors at the gate bias of |9 V| after irradiation by Co-60 gamma ray source. Although the sensitivity of the devices under test were strongly dependent to biasing condition and transistor type, the threshold voltage shifted linearly versus accumulated dose in all cases. The overall results show that the application of CD4007 as an electronic buffer in a radiation therapy system is limited by TID damage. However, this integrated circuit can be used as a cheap and sensitive radiation dosimeter for accumulated dose measurement in radiation therapy systems. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=threshold%20voltage%20shift" title="threshold voltage shift">threshold voltage shift</a>, <a href="https://publications.waset.org/abstracts/search?q=MOS%20transistor" title=" MOS transistor"> MOS transistor</a>, <a href="https://publications.waset.org/abstracts/search?q=linear%20extrapolation" title=" linear extrapolation"> linear extrapolation</a>, <a href="https://publications.waset.org/abstracts/search?q=gamma%20irradiation" title=" gamma irradiation"> gamma irradiation</a> </p> <a href="https://publications.waset.org/abstracts/55355/investigation-of-threshold-voltage-shift-in-gamma-irradiated-n-channel-and-p-channel-mos-transistors-of-cd4007" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/55355.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">283</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10024</span> Evaluation of Dynamic Log Files for Different Dose Rates in IMRT Plans </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Saad%20Bin%20Saeed">Saad Bin Saeed</a>, <a href="https://publications.waset.org/abstracts/search?q=Fayzan%20Ahmed"> Fayzan Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Shahbaz%20Ahmed"> Shahbaz Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Amjad%20Hussain"> Amjad Hussain</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of this study is to evaluate dynamic log files (Dynalogs) at different dose rates by dose-volume histograms (DVH) and used as a (QA) procedure of IMRT. Seven patients of phase one head and neck cancer with similar OAR`s are selected randomly. Reference plans of dose rate 300 and 600 MU/Min with prescribed dose of 50Gy in 25 fractions for each patient is made. Dynalogs produced by delivery of reference plans processed by in-house MATLAB program which produces new field files contain actual positions of multi-leaf collimators (MLC`s) instead of planned positions in reference plans. Copies of reference plans are used to import new field files generated by MATLAB program and renamed as Dyn.plan. After dose calculations of Dyn.plans for different dose rates, DVH, and multiple linear regression tools are used to evaluate reference and Dyn.plans. The results indicate good agreement of correlation between different dose rate plans. The maximum dose difference among PTV and OAR`s are found to be less than 5% and 9% respectively. The study indicates the potential of dynalogs to be used as patient-specific QA of IMRT at different dose rate. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=IMRT" title="IMRT">IMRT</a>, <a href="https://publications.waset.org/abstracts/search?q=dynalogs" title=" dynalogs"> dynalogs</a>, <a href="https://publications.waset.org/abstracts/search?q=dose%20rate" title=" dose rate"> dose rate</a>, <a href="https://publications.waset.org/abstracts/search?q=DVH" title=" DVH"> DVH</a> </p> <a href="https://publications.waset.org/abstracts/24120/evaluation-of-dynamic-log-files-for-different-dose-rates-in-imrt-plans" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/24120.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">535</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10023</span> Hepatoprotective Action of Emblica officinalis Linn. against Radiation and Lead Induced Changes in Swiss Albino Mice</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=R.%20K.%20Purohit">R. K. Purohit</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Ionizing radiation induces cellular damage through direct ionization of DNA and other cellular targets and indirectly via reactive oxygen species which may include effects from epigenetic changes. So there is a need of hour is to search for an ideal radioprotector which could minimize the deleterious and damaging effects caused by ionizing radiation. Radioprotectors are agents which reduce the radiation effects on cell when applied prior to exposure of radiation. The aim of this study was to access the efficacy of Emblica officinalis in reducing radiation and lead induced changes in mice liver. For the present experiment, healthy male Swiss albino mice (6-8 weeks) were selected and maintained under standard conditions of temperature and light. Fruit extract of Emblica was fed orally at the dose of 0.01 ml/animal/day. The animal were divided into seven groups according to the treatment i.e. lead acetate solution as drinking water (group-II) or exposed to 3.5 or 7.0 Gy gamma radiation (group-III) or combined treatment of radiation and lead acetate (group-IV). The animals of experimental groups were administered Emblica extract seven days prior to radiation or lead acetate treatment (group V, VI and VII) respectively. The animals from all the groups were sacrificed by cervical dislocation at each post-treatment intervals of 1, 2, 4, 7, 14 and 28 days. After sacrificing the animals pieces of liver were taken out and some of them were kept at -20°C for different biochemical parameters. The histopathological changes included cytoplasmic degranulation, vacuolation, hyperaemia, pycnotic and crenated nuclei. The changes observed in the control groups were compared with the respective experimental groups. An increase in the value of total proteins, glycogen, acid phosphtase, alkaline phosphatase activity and RNA was observed up to day-14 in the non drug treated group and day 7 in the Emblica treated groups, thereafter value declined up to day-28 without reaching to normal. The value of cholesterol and DNA showed a decreasing trend up to day -14 in non drug treated groups and day-7 in drug treated groups, thereafter value elevated up to day-28. The biochemical parameters were observed in the form of increase or decrease in the values. The changes were found dose dependent. After combined treatment of radiation and lead acetate synergistic effect were observed. The liver of Emblica treated animals exhibited less severe damage as compared to non-drug treated animals at all the corresponding intervals. An early and fast recovery was also noticed in Emblica pretreated animals. Thus, it appears that Emblica is potent enough to check lead and radiation induced heptic lesion in Swiss albino mice. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=radiation" title="radiation">radiation</a>, <a href="https://publications.waset.org/abstracts/search?q=lead" title=" lead "> lead </a>, <a href="https://publications.waset.org/abstracts/search?q=emblica" title=" emblica"> emblica</a>, <a href="https://publications.waset.org/abstracts/search?q=mice" title=" mice"> mice</a>, <a href="https://publications.waset.org/abstracts/search?q=liver" title=" liver"> liver</a> </p> <a href="https://publications.waset.org/abstracts/7341/hepatoprotective-action-of-emblica-officinalis-linn-against-radiation-and-lead-induced-changes-in-swiss-albino-mice" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/7341.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">322</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10022</span> Evaluation of Radio Protective Potential of Indian Bamboo Leaves</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mansi%20Patel">Mansi Patel</a>, <a href="https://publications.waset.org/abstracts/search?q=Priti%20Mehta"> Priti Mehta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Ionizing radiations have detrimental effects on humans, and the growing technological encroachment has increased human exposure to it enormously. So, the safety issues have emphasized researchers to develop radioprotector from natural resources having minimal toxicity. A substance having anti-inflammatory, antioxidant, and immunomodulatory activity can be a potential candidate for radioprotection. One such plant with immense potential i.e. Bamboo was selected for the present study. Purpose: The study aims to evaluate the potential of Indian bamboo leaves for protection against the clastogenic effect of gamma radiation. Methods: The protective effect of bamboo leaf extract against gamma radiation-induced genetic damage in human peripheral blood lymphocytes (HPBLs) was evaluated in vitro using Cytokinesis blocked micronuclei assay (CBMN). The blood samples were pretreated with varying concentration of extract 30 min before the radiation exposure (4Gy & 6Gy). The reduction in the frequency of micronuclei was observed for the irradiated and control groups. The effect of various concentration of bamboo leaf extract (400,600,800 mg/kg) on the development of radiation induced sickness and altered mortality in mice exposed to 8 Gy of whole-body gamma radiation was studied. The developed symptoms were clinically scored by multiple endpoints for 30 days. Results: Treatment of HPBLs with varying concentration of extract before exposure to a different dose of γ- radiation resulted in significant (P < 0.0001) decline of radiation induced micronuclei. It showed dose dependent and concentration driven activity. The maximum protection ~ 70% was achieved at nine µg/ml concentration. Extract treated whole body irradiated mice showed 50%, 83.3% and 100% survival for 400, 600, and 800mg/kg with 1.05, 0.43 and 0 clinical score respectively when compared to Irradiated mice having 6.03 clinical score and 0% survival. Conclusion: Our findings indicate bamboo leaf extract reduced the radiation induced cytogenetic damage. It has also increased the survival ratio and reduced the radiation induced sickness and mortality when exposed to a lethal dose of gamma radiation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bamboo%20leaf%20extract" title="bamboo leaf extract">bamboo leaf extract</a>, <a href="https://publications.waset.org/abstracts/search?q=Cytokinesis%20blocked%20micronuclei%20%28CBMN%29%20assay" title=" Cytokinesis blocked micronuclei (CBMN) assay"> Cytokinesis blocked micronuclei (CBMN) assay</a>, <a href="https://publications.waset.org/abstracts/search?q=ionizing%20radiation" title=" ionizing radiation"> ionizing radiation</a>, <a href="https://publications.waset.org/abstracts/search?q=radio%20protector" title=" radio protector"> radio protector</a> </p> <a href="https://publications.waset.org/abstracts/99802/evaluation-of-radio-protective-potential-of-indian-bamboo-leaves" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/99802.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">146</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10021</span> Estimation of Hydrogen Production from PWR Spent Fuel Due to Alpha Radiolysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sivakumar%20Kottapalli">Sivakumar Kottapalli</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdesselam%20Abdelouas"> Abdesselam Abdelouas</a>, <a href="https://publications.waset.org/abstracts/search?q=Christoph%20Hartnack"> Christoph Hartnack</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Spent nuclear fuel generates a mixed field of ionizing radiation to the water. This radiation field is generally dominated by gamma rays and a limited flux of fast neutrons. The fuel cladding effectively attenuates beta and alpha particle radiation. Small fraction of the spent nuclear fuel exhibits some degree of fuel cladding penetration due to pitting corrosion and mechanical failure. Breaches in the fuel cladding allow the exposure of small volumes of water in the cask to alpha and beta ionizing radiation. The safety of the transport of radioactive material is assured by the package complying with the IAEA Requirements for the Safe Transport of Radioactive Material SSR-6. It is of high interest to avoid generation of hydrogen inside the cavity which may to an explosive mixture. The risk of hydrogen production along with other radiation gases should be analyzed for a typical spent fuel for safety issues. This work aims to perform a realistic study of the production of hydrogen by radiolysis assuming most penalizing initial conditions. It consists in the calculation of the radionuclide inventory of a pellet taking into account the burn up and decays. Westinghouse 17X17 PWR fuel has been chosen and data has been analyzed for different sets of enrichment, burnup, cycles of irradiation and storage conditions. The inventory is calculated as the entry point for the simulation studies of hydrogen production by radiolysis kinetic models by MAKSIMA-CHEMIST. Dose rates decrease strongly within ~45 μm from the fuel surface towards the solution(water) in case of alpha radiation, while the dose rate decrease is lower in case of beta and even slower in case of gamma radiation. Calculations are carried out to obtain spectra as a function of time. Radiation dose rate profiles are taken as the input data for the iterative calculations. Hydrogen yield has been found to be around 0.02 mol/L. Calculations have been performed for a realistic scenario considering a capsule containing the spent fuel rod. Thus, hydrogen yield has been debated. Experiments are under progress to validate the hydrogen production rate using cyclotron at > 5MeV (at ARRONAX, Nantes). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=radiolysis" title="radiolysis">radiolysis</a>, <a href="https://publications.waset.org/abstracts/search?q=spent%20fuel" title=" spent fuel"> spent fuel</a>, <a href="https://publications.waset.org/abstracts/search?q=hydrogen" title=" hydrogen"> hydrogen</a>, <a href="https://publications.waset.org/abstracts/search?q=cyclotron" title=" cyclotron"> cyclotron</a> </p> <a href="https://publications.waset.org/abstracts/34769/estimation-of-hydrogen-production-from-pwr-spent-fuel-due-to-alpha-radiolysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/34769.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">521</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10020</span> Evaluating the Radiation Dose Involved in Interventional Radiology Procedures</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kholood%20Baron">Kholood Baron</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Radiologic interventional studies use fluoroscopy imaging guidance to perform both diagnostic and therapeutic procedures. These could result in high radiation doses being delivered to the patients and also to the radiology team. This is due to the prolonged fluoroscopy time and the large number of images taken, even when dose-minimizing techniques and modern fluoroscopic tools are applied. Hence, these procedures are part of the everyday routine of interventional radiology doctors, assistant nurses, and radiographers. Thus, it is important to estimate the radiation exposure dose they received in order to give objective advice and reduce both patient and radiology team radiation exposure dose. The aim of this study was to find out the total radiation dose reaching the radiologist and the patient during an interventional procedure and to determine the impact of certain parameters on the patient dose. Method: The radiation dose was measured by TLD devices (thermoluminescent dosimeter; radiation dosimeter device). Physicians, patients, nurses, and radiographers wore TLDs during 12 interventional radiology procedures performed in two hospitals, Mubarak and Chest Hospital. This study highlights the need for interventional radiologists to be mindful of the radiation doses received by both patients and medical staff during interventional radiology procedures. The findings emphasize the impact of factors such as fluoroscopy duration and the number of images taken on the patient dose. By raising awareness and providing insights into optimizing techniques and protective measures, this research contributes to the overall goal of reducing radiation doses and ensuring the safety of patients and medical staff. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dosimetry" title="dosimetry">dosimetry</a>, <a href="https://publications.waset.org/abstracts/search?q=radiation%20dose" title=" radiation dose"> radiation dose</a>, <a href="https://publications.waset.org/abstracts/search?q=interventional%20radiology%20procedures" title=" interventional radiology procedures"> interventional radiology procedures</a>, <a href="https://publications.waset.org/abstracts/search?q=patient%20radiation%20dose" title=" patient radiation dose"> patient radiation dose</a> </p> <a href="https://publications.waset.org/abstracts/174903/evaluating-the-radiation-dose-involved-in-interventional-radiology-procedures" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/174903.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">113</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10019</span> Design, Shielding and Infrastructure of an X-Ray Diagnostic Imaging Area</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=D.%20Diaz">D. Diaz</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Guevara"> C. Guevara</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Rey"> P. Rey </a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper contains information about designing, shielding and protocols building in order to avoid ionizing radiation in X-Rays imaging areas as generated by X-Ray, mammography equipment, computed tomography equipment and digital subtraction angiography equipment, according to global standards. Furthermore, tools and elements about infrastructure to improve protection over patients, physicians and staff involved in a diagnostic imaging area are presented. In addition, technical parameters about each machine and the architecture designs and maps are described. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=imaging%20area" title="imaging area">imaging area</a>, <a href="https://publications.waset.org/abstracts/search?q=X-ray" title=" X-ray"> X-ray</a>, <a href="https://publications.waset.org/abstracts/search?q=shielding" title=" shielding"> shielding</a>, <a href="https://publications.waset.org/abstracts/search?q=dose" title=" dose"> dose</a> </p> <a href="https://publications.waset.org/abstracts/4161/design-shielding-and-infrastructure-of-an-x-ray-diagnostic-imaging-area" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/4161.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">448</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10018</span> Study of Radiation Response in Lactobacillus Species</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kanika%20Arora">Kanika Arora</a>, <a href="https://publications.waset.org/abstracts/search?q=Madhu%20Bala"> Madhu Bala</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The small intestine epithelium is highly sensitive and major targets of ionizing radiation. Radiation causes gastrointestinal toxicity either by direct deposition of energy or indirectly (inflammation or bystander effects) generating free radicals and reactive oxygen species. Oxidative stress generated as a result of radiation causes active inflammation within the intestinal mucosa leading to structural and functional impairment of gut epithelial barrier. As a result, there is a loss of tolerance to normal dietary antigens and commensal flora together with exaggerated response to pathogens. Dysbiosis may therefore thought to play a role in radiation enteropathy and can contribute towards radiation induced bowel toxicity. Lactobacilli residing in the gut shares a long conjoined evolutionary history with their hosts and by doing so these organisms have developed an intimate and complex symbiotic relationships. The objective behind this study was to look for the strains with varying resistance to ionizing radiation and to see whether the niche of the bacteria is playing any role in radiation resistance property of bacteria. In this study, we have isolated the Lactobacillus spp. from probiotic preparation and murine gastrointestinal tract, both of which were supposed to be the important source for its isolation. Biochemical characterization did not show a significant difference in the properties, while a significant preference was observed in carbohydrate utilization capacity by the isolates. Effect of ionizing radiations induced by Co60 gamma radiation (10 Gy) on lactobacilli cells was investigated. A cellular survival curve versus absorbed doses was determined. Radiation resistance studies showed that the response of isolates towards cobalt-60 gamma radiation differs from each other and significant decrease in survival was observed in a dose-dependent manner. Thus the present study revealed that the property of radioresistance in Lactobacillus depends upon the source from where they have been isolated. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dysbiosis" title="dysbiosis">dysbiosis</a>, <a href="https://publications.waset.org/abstracts/search?q=lactobacillus" title=" lactobacillus"> lactobacillus</a>, <a href="https://publications.waset.org/abstracts/search?q=mitigation" title=" mitigation"> mitigation</a>, <a href="https://publications.waset.org/abstracts/search?q=radiation" title=" radiation"> radiation</a> </p> <a href="https://publications.waset.org/abstracts/84937/study-of-radiation-response-in-lactobacillus-species" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/84937.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">137</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10017</span> Alternative of Lead-Based Ionization Radiation Shielding Property: Epoxy-Based Composite Design</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Md.%20Belal%20Uudin%20Rabbi">Md. Belal Uudin Rabbi</a>, <a href="https://publications.waset.org/abstracts/search?q=Sakib%20Al%20Montasir"> Sakib Al Montasir</a>, <a href="https://publications.waset.org/abstracts/search?q=Saifur%20Rahman"> Saifur Rahman</a>, <a href="https://publications.waset.org/abstracts/search?q=Niger%20Nahid"> Niger Nahid</a>, <a href="https://publications.waset.org/abstracts/search?q=Esmail%20Hossain%20Emon"> Esmail Hossain Emon</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The practice of radiation shielding protects against the detrimental effects of ionizing radiation. Radiation shielding depletes radiation by inserting a shield of absorbing material between any radioactive source. It is a primary concern when building several industrial fields, so using potent (high activity) radioisotopes in food preservation, cancer treatment, and particle accelerator facilities is significant. Radiation shielding is essential for radiation-emitting equipment users to reduce or mitigate radiation damage. Polymer composites (especially epoxy based) with high atomic number fillers can replace toxic Lead in ionizing radiation shielding applications because of their excellent mechanical properties, superior solvent and chemical resistance, good dimensional stability, adhesive, and less toxic. Due to being lightweight, good neutron shielding ability in almost the same order as concrete, epoxy-based radiation shielding can be the next big thing. Micro and nano-particles for the epoxy resin increase the epoxy matrix's radiation shielding property. Shielding is required to protect users of such facilities from ionizing radiation as recently, and considerable attention has been paid to polymeric composites as a radiation shielding material. This research will examine the radiation shielding performance of epoxy-based nano-WO3 reinforced composites, exploring the performance of epoxy-based nano-WO3 reinforced composites. The samples will be prepared using the direct pouring method to block radiation. The practice of radiation shielding protects against the detrimental effects of ionizing radiation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=radiation%20shielding%20materials" title="radiation shielding materials">radiation shielding materials</a>, <a href="https://publications.waset.org/abstracts/search?q=ionizing%20radiation" title=" ionizing radiation"> ionizing radiation</a>, <a href="https://publications.waset.org/abstracts/search?q=epoxy%20resin" title=" epoxy resin"> epoxy resin</a>, <a href="https://publications.waset.org/abstracts/search?q=Tungsten%20oxide" title=" Tungsten oxide"> Tungsten oxide</a>, <a href="https://publications.waset.org/abstracts/search?q=polymer%20composites" title=" polymer composites"> polymer composites</a> </p> <a href="https://publications.waset.org/abstracts/161275/alternative-of-lead-based-ionization-radiation-shielding-property-epoxy-based-composite-design" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/161275.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">114</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10016</span> Development of a Model for Predicting Radiological Risks in Interventional Cardiology</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Stefaan%20Carpentier">Stefaan Carpentier</a>, <a href="https://publications.waset.org/abstracts/search?q=Aya%20Al%20Masri"> Aya Al Masri</a>, <a href="https://publications.waset.org/abstracts/search?q=Fabrice%20Leroy"> Fabrice Leroy</a>, <a href="https://publications.waset.org/abstracts/search?q=Thibault%20Julien"> Thibault Julien</a>, <a href="https://publications.waset.org/abstracts/search?q=Safoin%20Aktaou"> Safoin Aktaou</a>, <a href="https://publications.waset.org/abstracts/search?q=Malorie%20Martin"> Malorie Martin</a>, <a href="https://publications.waset.org/abstracts/search?q=Fouad%20Maaloul"> Fouad Maaloul</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: During an 'Interventional Radiology (IR)' procedure, the patient's skin-dose may become very high for a burn, necrosis, and ulceration to appear. In order to prevent these deterministic effects, a prediction of the peak skin-dose for the patient is important in order to improve the post-operative care to be given to the patient. The objective of this study is to estimate, before the intervention, the patient dose for ‘Chronic Total Occlusion (CTO)’ procedures by selecting relevant clinical indicators. Materials and methods: 103 procedures were performed in the ‘Interventional Cardiology (IC)’ department using a Siemens Artis Zee image intensifier that provides the Air Kerma of each IC exam. Peak Skin Dose (PSD) was measured for each procedure using radiochromic films. Patient parameters such as sex, age, weight, and height were recorded. The complexity index J-CTO score, specific to each intervention, was determined by the cardiologist. A correlation method applied to these indicators allowed to specify their influence on the dose. A predictive model of the dose was created using multiple linear regressions. Results: Out of 103 patients involved in the study, 5 were excluded for clinical reasons and 2 for placement of radiochromic films outside the exposure field. 96 2D-dose maps were finally used. The influencing factors having the highest correlation with the PSD are the patient's diameter and the J-CTO score. The predictive model is based on these parameters. The comparison between estimated and measured skin doses shows an average difference of 0.85 ± 0.55 Gy for doses of less than 6 Gy. The mean difference between air-Kerma and PSD is 1.66 Gy ± 1.16 Gy. Conclusion: Using our developed method, a first estimate of the dose to the skin of the patient is available before the start of the procedure, which helps the cardiologist in carrying out its intervention. This estimation is more accurate than that provided by the Air-Kerma. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chronic%20total%20occlusion%20procedures" title="chronic total occlusion procedures">chronic total occlusion procedures</a>, <a href="https://publications.waset.org/abstracts/search?q=clinical%20experimentation" title=" clinical experimentation"> clinical experimentation</a>, <a href="https://publications.waset.org/abstracts/search?q=interventional%20radiology" title=" interventional radiology"> interventional radiology</a>, <a href="https://publications.waset.org/abstracts/search?q=patient%27s%20peak%20skin%20dose" title=" patient's peak skin dose"> patient's peak skin dose</a> </p> <a href="https://publications.waset.org/abstracts/119029/development-of-a-model-for-predicting-radiological-risks-in-interventional-cardiology" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/119029.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">137</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10015</span> CT Doses Pre and Post SAFIRE: Sinogram Affirmed Iterative Reconstruction</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=N.%20Noroozian">N. Noroozian</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Halim"> M. Halim</a>, <a href="https://publications.waset.org/abstracts/search?q=B.%20Holloway"> B. Holloway</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Computed Tomography (CT) has become the largest source of radiation exposure in modern countries however, recent technological advances have created new methods to reduce dose without negatively affecting image quality. SAFIRE has emerged as a new software package which utilizes full raw data projections for iterative reconstruction, thereby allowing for lower CT dose to be used. this audit was performed to compare CT doses in certain examinations before and after the introduction of SAFIRE at our Radiology department which showed CT doses were significantly lower using SAFIRE compared with pre-SAFIRE software at SAFIRE 3 setting for the following studies:CSKUH Unenhanced brain scans (-20.9%), CABPEC Abdomen and pelvis with contrast (-21.5%), CCHAPC Chest with contrast (-24.4%), CCHAPC Abdomen and pelvis with contrast (-16.1%), CCHAPC Total chest, abdomen and pelvis (-18.7%). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dose%20reduction" title="dose reduction">dose reduction</a>, <a href="https://publications.waset.org/abstracts/search?q=iterative%20reconstruction" title=" iterative reconstruction"> iterative reconstruction</a>, <a href="https://publications.waset.org/abstracts/search?q=low%20dose%20CT%20techniques" title=" low dose CT techniques"> low dose CT techniques</a>, <a href="https://publications.waset.org/abstracts/search?q=SAFIRE" title=" SAFIRE"> SAFIRE</a> </p> <a href="https://publications.waset.org/abstracts/18344/ct-doses-pre-and-post-safire-sinogram-affirmed-iterative-reconstruction" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/18344.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">285</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10014</span> All Types of Base Pair Substitutions Induced by γ-Rays in Haploid and Diploid Yeast Cells</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Natalia%20Koltovaya">Natalia Koltovaya</a>, <a href="https://publications.waset.org/abstracts/search?q=Nadezhda%20Zhuchkina"> Nadezhda Zhuchkina</a>, <a href="https://publications.waset.org/abstracts/search?q=Ksenia%20Lyubimova"> Ksenia Lyubimova</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We study the biological effects induced by ionizing radiation in view of therapeutic exposure and the idea of space flights beyond Earth's magnetosphere. In particular, we examine the differences between base pair substitution induction by ionizing radiation in model haploid and diploid yeast <em>Saccharomyces cerevisiae</em> cells. Such mutations are difficult to study in higher eukaryotic systems. In our research, we have used a collection of six isogenic <em>trp5</em>-strains and 14 isogenic haploid and diploid <em>cyc1</em>-strains that are specific markers of all possible base-pair substitutions. These strains differ from each other only in single base substitutions within codon-50 of the <em>trp5</em> gene or codon-22 of the <em>cyc1</em> gene. Different mutation spectra for two different haploid genetic <em>trp5</em>- and <em>cyc1</em>-assays and different mutation spectra for the same genetic <em>cyc1</em>-system in cells with different ploidy — haploid and diploid — have been obtained. It was linear function for dose-dependence in haploid and exponential in diploid cells. We suggest that the differences between haploid yeast strains reflect the dependence on the sequence context, while the differences between haploid and diploid strains reflect the different molecular mechanisms of mutations. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=base%20pair%20substitutions" title="base pair substitutions">base pair substitutions</a>, <a href="https://publications.waset.org/abstracts/search?q=%CE%B3-rays" title=" γ-rays"> γ-rays</a>, <a href="https://publications.waset.org/abstracts/search?q=haploid%20and%20diploid%20cells" title=" haploid and diploid cells"> haploid and diploid cells</a>, <a href="https://publications.waset.org/abstracts/search?q=yeast%20Saccharomyces%20cerevisiae" title=" yeast Saccharomyces cerevisiae"> yeast Saccharomyces cerevisiae</a> </p> <a href="https://publications.waset.org/abstracts/91922/all-types-of-base-pair-substitutions-induced-by-gh-rays-in-haploid-and-diploid-yeast-cells" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/91922.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">155</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">&lsaquo;</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=total%20ionizing%20dose&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=total%20ionizing%20dose&page=3">3</a></li> <li class="page-item"><a class="page-link" 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