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Snakebite - Wikipedia

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class="vector-toc-numb">2</span> <span>Cause</span> </div> </a> <ul id="toc-Cause-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Pathophysiology" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Pathophysiology"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Pathophysiology</span> </div> </a> <button aria-controls="toc-Pathophysiology-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Pathophysiology subsection</span> </button> <ul id="toc-Pathophysiology-sublist" class="vector-toc-list"> <li id="toc-Snake_venom" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Snake_venom"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.1</span> <span>Snake venom</span> </div> </a> <ul id="toc-Snake_venom-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Prevention" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Prevention"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Prevention</span> </div> </a> <ul id="toc-Prevention-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Treatment" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Treatment"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Treatment</span> </div> </a> <button aria-controls="toc-Treatment-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Treatment subsection</span> </button> <ul id="toc-Treatment-sublist" class="vector-toc-list"> <li id="toc-Snake_identification" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Snake_identification"> <div class="vector-toc-text"> <span class="vector-toc-numb">5.1</span> <span>Snake identification</span> </div> </a> <ul id="toc-Snake_identification-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-First_aid" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#First_aid"> <div class="vector-toc-text"> <span class="vector-toc-numb">5.2</span> <span>First aid</span> </div> </a> <ul id="toc-First_aid-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Pressure_immobilization" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Pressure_immobilization"> <div class="vector-toc-text"> <span class="vector-toc-numb">5.3</span> <span>Pressure immobilization</span> </div> </a> <ul id="toc-Pressure_immobilization-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Antivenom" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Antivenom"> <div class="vector-toc-text"> <span class="vector-toc-numb">5.4</span> <span>Antivenom</span> </div> </a> <ul id="toc-Antivenom-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Chronic_Complications" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Chronic_Complications"> <div class="vector-toc-text"> <span class="vector-toc-numb">5.5</span> <span>Chronic Complications</span> </div> </a> <ul id="toc-Chronic_Complications-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Outmoded" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Outmoded"> <div class="vector-toc-text"> <span class="vector-toc-numb">5.6</span> <span>Outmoded</span> </div> </a> <ul id="toc-Outmoded-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-In_development" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#In_development"> <div class="vector-toc-text"> <span class="vector-toc-numb">5.7</span> <span>In development</span> </div> </a> <ul id="toc-In_development-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Epidemiology" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Epidemiology"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>Epidemiology</span> </div> </a> <ul id="toc-Epidemiology-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Mechanics" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Mechanics"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>Mechanics</span> </div> </a> <button aria-controls="toc-Mechanics-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Mechanics subsection</span> </button> <ul id="toc-Mechanics-sublist" class="vector-toc-list"> <li id="toc-Predatory_vs._defensive_bites" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Predatory_vs._defensive_bites"> <div class="vector-toc-text"> <span class="vector-toc-numb">7.1</span> <span>Predatory vs. defensive bites</span> </div> </a> <ul id="toc-Predatory_vs._defensive_bites-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Venom_Metering" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Venom_Metering"> <div class="vector-toc-text"> <span class="vector-toc-numb">7.2</span> <span>Venom Metering</span> </div> </a> <ul id="toc-Venom_Metering-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Venom_Spitting" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Venom_Spitting"> <div class="vector-toc-text"> <span class="vector-toc-numb">7.3</span> <span>Venom Spitting</span> </div> </a> <ul id="toc-Venom_Spitting-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Society_and_culture" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Society_and_culture"> <div class="vector-toc-text"> <span class="vector-toc-numb">8</span> <span>Society and culture</span> </div> </a> <ul id="toc-Society_and_culture-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Research" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Research"> <div class="vector-toc-text"> <span class="vector-toc-numb">9</span> <span>Research</span> </div> </a> <ul id="toc-Research-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Other_animals" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Other_animals"> <div class="vector-toc-text"> <span class="vector-toc-numb">10</span> <span>Other animals</span> </div> </a> <ul id="toc-Other_animals-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">11</span> <span>References</span> </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Further_reading" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Further_reading"> <div class="vector-toc-text"> <span class="vector-toc-numb">12</span> <span>Further reading</span> </div> </a> <ul id="toc-Further_reading-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-External_links" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#External_links"> <div class="vector-toc-text"> <span class="vector-toc-numb">13</span> <span>External links</span> </div> </a> <ul id="toc-External_links-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contents" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" title="Table of Contents" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Toggle the table of contents" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Toggle the table of contents</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Snakebite</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. Available in 50 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-50" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">50 languages</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%84%D8%AF%D8%BA%D8%A9_%D8%AB%D8%B9%D8%A8%D8%A7%D9%86" title="لدغة ثعبان – Arabic" lang="ar" hreflang="ar" data-title="لدغة ثعبان" data-language-autonym="العربية" data-language-local-name="Arabic" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-as badge-Q17437796 badge-featuredarticle mw-list-item" title="featured article badge"><a href="https://as.wikipedia.org/wiki/%E0%A6%B8%E0%A7%B0%E0%A7%8D%E0%A6%AA%E0%A6%A6%E0%A6%82%E0%A6%B6%E0%A6%A8" title="সৰ্পদংশন – Assamese" lang="as" hreflang="as" data-title="সৰ্পদংশন" data-language-autonym="অসমীয়া" data-language-local-name="Assamese" class="interlanguage-link-target"><span>অসমীয়া</span></a></li><li class="interlanguage-link interwiki-ast mw-list-item"><a href="https://ast.wikipedia.org/wiki/Mordedura_de_culiebra" title="Mordedura de culiebra – Asturian" lang="ast" hreflang="ast" data-title="Mordedura de culiebra" data-language-autonym="Asturianu" data-language-local-name="Asturian" class="interlanguage-link-target"><span>Asturianu</span></a></li><li class="interlanguage-link interwiki-bn mw-list-item"><a href="https://bn.wikipedia.org/wiki/%E0%A6%B8%E0%A6%B0%E0%A7%8D%E0%A6%AA%E0%A6%A6%E0%A6%82%E0%A6%B6%E0%A6%A8" title="সর্পদংশন – Bangla" lang="bn" hreflang="bn" data-title="সর্পদংশন" data-language-autonym="বাংলা" data-language-local-name="Bangla" class="interlanguage-link-target"><span>বাংলা</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Picada_de_serp" title="Picada de serp – Catalan" lang="ca" hreflang="ca" data-title="Picada de serp" data-language-autonym="Català" data-language-local-name="Catalan" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/U%C5%A1tknut%C3%AD_hadem" title="Uštknutí hadem – Czech" lang="cs" hreflang="cs" data-title="Uštknutí hadem" data-language-autonym="Čeština" data-language-local-name="Czech" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Schlangenbiss" title="Schlangenbiss – German" lang="de" hreflang="de" data-title="Schlangenbiss" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/Maohammustus" title="Maohammustus – Estonian" lang="et" hreflang="et" data-title="Maohammustus" data-language-autonym="Eesti" data-language-local-name="Estonian" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Mordedura_de_serpiente" title="Mordedura de serpiente – Spanish" lang="es" hreflang="es" data-title="Mordedura de serpiente" data-language-autonym="Español" data-language-local-name="Spanish" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Suge-hozkada" title="Suge-hozkada – Basque" lang="eu" hreflang="eu" data-title="Suge-hozkada" data-language-autonym="Euskara" data-language-local-name="Basque" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%85%D8%A7%D8%B1%DA%AF%D8%B2%DB%8C%D8%AF%DA%AF%DB%8C" title="مارگزیدگی – Persian" lang="fa" hreflang="fa" data-title="مارگزیدگی" data-language-autonym="فارسی" data-language-local-name="Persian" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Morsure_de_serpent" title="Morsure de serpent – French" lang="fr" hreflang="fr" data-title="Morsure de serpent" data-language-autonym="Français" data-language-local-name="French" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Trabada_de_serpe" title="Trabada de serpe – Galician" lang="gl" hreflang="gl" data-title="Trabada de serpe" data-language-autonym="Galego" data-language-local-name="Galician" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EC%82%AC%EA%B5%90%EC%83%81" title="사교상 – Korean" lang="ko" hreflang="ko" data-title="사교상" data-language-autonym="한국어" data-language-local-name="Korean" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-ha mw-list-item"><a href="https://ha.wikipedia.org/wiki/Cizon_maciji" title="Cizon maciji – Hausa" lang="ha" hreflang="ha" data-title="Cizon maciji" data-language-autonym="Hausa" data-language-local-name="Hausa" class="interlanguage-link-target"><span>Hausa</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D5%95%D5%B1%D5%AB_%D5%AD%D5%A1%D5%B5%D5%A9%D5%B8%D6%81" title="Օձի խայթոց – Armenian" lang="hy" hreflang="hy" data-title="Օձի խայթոց" data-language-autonym="Հայերեն" data-language-local-name="Armenian" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%B8%E0%A4%B0%E0%A5%8D%E0%A4%AA%E0%A4%A6%E0%A4%82%E0%A4%B6" title="सर्पदंश – Hindi" lang="hi" hreflang="hi" data-title="सर्पदंश" data-language-autonym="हिन्दी" data-language-local-name="Hindi" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Ugriz_zmije" title="Ugriz zmije – Croatian" lang="hr" hreflang="hr" data-title="Ugriz zmije" data-language-autonym="Hrvatski" data-language-local-name="Croatian" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Gigitan_ular" title="Gigitan ular – Indonesian" lang="id" hreflang="id" data-title="Gigitan ular" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonesian" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%94%D7%9B%D7%A9%D7%AA_%D7%A0%D7%97%D7%A9" title="הכשת נחש – Hebrew" lang="he" hreflang="he" data-title="הכשת נחש" data-language-autonym="עברית" data-language-local-name="Hebrew" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-jv mw-list-item"><a href="https://jv.wikipedia.org/wiki/Cokotan_ula" title="Cokotan ula – Javanese" lang="jv" hreflang="jv" data-title="Cokotan ula" data-language-autonym="Jawa" data-language-local-name="Javanese" class="interlanguage-link-target"><span>Jawa</span></a></li><li class="interlanguage-link interwiki-kn mw-list-item"><a href="https://kn.wikipedia.org/wiki/%E0%B2%B9%E0%B2%BE%E0%B2%B5%E0%B3%81_%E0%B2%95%E0%B2%A1%E0%B2%BF%E0%B2%A4" title="ಹಾವು ಕಡಿತ – Kannada" lang="kn" hreflang="kn" data-title="ಹಾವು ಕಡಿತ" data-language-autonym="ಕನ್ನಡ" data-language-local-name="Kannada" class="interlanguage-link-target"><span>ಕನ್ನಡ</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Gyvat%C4%97s_%C4%AFkirtimas" title="Gyvatės įkirtimas – Lithuanian" lang="lt" hreflang="lt" data-title="Gyvatės įkirtimas" data-language-autonym="Lietuvių" data-language-local-name="Lithuanian" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-lg mw-list-item"><a href="https://lg.wikipedia.org/wiki/Ekisubi_kimusaze" title="Ekisubi kimusaze – Ganda" lang="lg" hreflang="lg" data-title="Ekisubi kimusaze" data-language-autonym="Luganda" data-language-local-name="Ganda" class="interlanguage-link-target"><span>Luganda</span></a></li><li class="interlanguage-link interwiki-mr mw-list-item"><a href="https://mr.wikipedia.org/wiki/%E0%A4%B8%E0%A4%B0%E0%A5%8D%E0%A4%AA%E0%A4%A6%E0%A4%82%E0%A4%B6" title="सर्पदंश – Marathi" lang="mr" hreflang="mr" data-title="सर्पदंश" data-language-autonym="मराठी" data-language-local-name="Marathi" class="interlanguage-link-target"><span>मराठी</span></a></li><li class="interlanguage-link interwiki-arz mw-list-item"><a href="https://arz.wikipedia.org/wiki/%D9%84%D8%AF%D8%BA%D8%A9_%D8%AA%D8%B9%D8%A8%D8%A7%D9%86" title="لدغة تعبان – Egyptian Arabic" lang="arz" hreflang="arz" data-title="لدغة تعبان" data-language-autonym="مصرى" data-language-local-name="Egyptian Arabic" class="interlanguage-link-target"><span>مصرى</span></a></li><li class="interlanguage-link interwiki-mnw mw-list-item"><a href="https://mnw.wikipedia.org/wiki/%E1%80%87%E1%80%BC%E1%80%AF%E1%80%B6%E1%81%9C%E1%80%B6%E1%80%80%E1%80%BA" title="ဇြုံၜံက် – Mon" lang="mnw" hreflang="mnw" data-title="ဇြုံၜံက်" data-language-autonym="ဘာသာမန်" data-language-local-name="Mon" class="interlanguage-link-target"><span>ဘာသာမန်</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Slangenbeet" title="Slangenbeet – Dutch" lang="nl" hreflang="nl" data-title="Slangenbeet" data-language-autonym="Nederlands" data-language-local-name="Dutch" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-ne mw-list-item"><a href="https://ne.wikipedia.org/wiki/%E0%A4%B8%E0%A4%B0%E0%A5%8D%E0%A4%AA%E0%A4%A6%E0%A4%82%E0%A4%B6" title="सर्पदंश – Nepali" lang="ne" hreflang="ne" data-title="सर्पदंश" data-language-autonym="नेपाली" data-language-local-name="Nepali" class="interlanguage-link-target"><span>नेपाली</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E8%9B%87%E5%92%AC%E5%82%B7" title="蛇咬傷 – Japanese" lang="ja" hreflang="ja" data-title="蛇咬傷" data-language-autonym="日本語" data-language-local-name="Japanese" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%B8%E0%AC%B0%E0%AD%8D%E0%AC%AA_%E0%AC%A6%E0%AC%82%E0%AC%B6" title="ସର୍ପ ଦଂଶ – Odia" lang="or" hreflang="or" data-title="ସର୍ପ ଦଂଶ" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="Odia" class="interlanguage-link-target"><span>ଓଡ଼ିଆ</span></a></li><li class="interlanguage-link interwiki-uz mw-list-item"><a href="https://uz.wikipedia.org/wiki/Ilon_chaqishi" title="Ilon chaqishi – Uzbek" lang="uz" hreflang="uz" data-title="Ilon chaqishi" data-language-autonym="Oʻzbekcha / ўзбекча" data-language-local-name="Uzbek" class="interlanguage-link-target"><span>Oʻzbekcha / ўзбекча</span></a></li><li class="interlanguage-link interwiki-pa mw-list-item"><a href="https://pa.wikipedia.org/wiki/%E0%A8%B8%E0%A9%B1%E0%A8%AA_%E0%A8%A6%E0%A8%BE_%E0%A8%A1%E0%A9%B1%E0%A8%B8%E0%A8%A3%E0%A8%BE" title="ਸੱਪ ਦਾ ਡੱਸਣਾ – Punjabi" lang="pa" hreflang="pa" data-title="ਸੱਪ ਦਾ ਡੱਸਣਾ" data-language-autonym="ਪੰਜਾਬੀ" data-language-local-name="Punjabi" class="interlanguage-link-target"><span>ਪੰਜਾਬੀ</span></a></li><li class="interlanguage-link interwiki-ps mw-list-item"><a href="https://ps.wikipedia.org/wiki/%D9%85%D8%A7%D8%B1%DA%86%D9%8A%DA%86%D9%84" title="مارچيچل – Pashto" lang="ps" hreflang="ps" data-title="مارچيچل" data-language-autonym="پښتو" data-language-local-name="Pashto" class="interlanguage-link-target"><span>پښتو</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Mordedura_de_serpente" title="Mordedura de serpente – Portuguese" lang="pt" hreflang="pt" data-title="Mordedura de serpente" data-language-autonym="Português" data-language-local-name="Portuguese" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%97%D0%BC%D0%B5%D0%B8%D0%BD%D1%8B%D0%B9_%D1%83%D0%BA%D1%83%D1%81" title="Змеиный укус – Russian" lang="ru" hreflang="ru" data-title="Змеиный укус" data-language-autonym="Русский" data-language-local-name="Russian" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sat mw-list-item"><a href="https://sat.wikipedia.org/wiki/%E1%B1%B5%E1%B1%A4%E1%B1%A7%E1%B1%9C%E1%B1%AE%E1%B1%A8" title="ᱵᱤᱧᱜᱮᱨ – Santali" lang="sat" hreflang="sat" data-title="ᱵᱤᱧᱜᱮᱨ" data-language-autonym="ᱥᱟᱱᱛᱟᱲᱤ" data-language-local-name="Santali" class="interlanguage-link-target"><span>ᱥᱟᱱᱛᱟᱲᱤ</span></a></li><li class="interlanguage-link interwiki-sq mw-list-item"><a href="https://sq.wikipedia.org/wiki/Kafshimi_i_gjarprit" title="Kafshimi i gjarprit – Albanian" lang="sq" hreflang="sq" data-title="Kafshimi i gjarprit" data-language-autonym="Shqip" data-language-local-name="Albanian" class="interlanguage-link-target"><span>Shqip</span></a></li><li class="interlanguage-link interwiki-si mw-list-item"><a href="https://si.wikipedia.org/wiki/%E0%B7%83%E0%B6%BB%E0%B7%8A%E0%B6%B4%E0%B6%BA%E0%B6%B1%E0%B7%8A_%E0%B6%AF%E0%B7%82%E0%B7%8A%E0%B6%A8%E0%B6%9A%E0%B7%92%E0%B6%BB%E0%B7%93%E0%B6%B8" title="සර්පයන් දෂ්ඨකිරීම – Sinhala" lang="si" hreflang="si" data-title="සර්පයන් දෂ්ඨකිරීම" data-language-autonym="සිංහල" data-language-local-name="Sinhala" class="interlanguage-link-target"><span>සිංහල</span></a></li><li class="interlanguage-link interwiki-sl badge-Q17437796 badge-featuredarticle mw-list-item" title="featured article badge"><a href="https://sl.wikipedia.org/wiki/Ka%C4%8Dji_ugriz" title="Kačji ugriz – Slovenian" lang="sl" hreflang="sl" data-title="Kačji ugriz" data-language-autonym="Slovenščina" data-language-local-name="Slovenian" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Zmijski_ujed" title="Zmijski ujed – Serbian" lang="sr" hreflang="sr" data-title="Zmijski ujed" data-language-autonym="Српски / srpski" data-language-local-name="Serbian" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/K%C3%A4%C3%A4rmeenpurema" title="Käärmeenpurema – Finnish" lang="fi" hreflang="fi" data-title="Käärmeenpurema" data-language-autonym="Suomi" data-language-local-name="Finnish" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a href="https://ta.wikipedia.org/wiki/%E0%AE%AA%E0%AE%BE%E0%AE%AE%E0%AF%8D%E0%AE%AA%E0%AF%81%E0%AE%95%E0%AF%8D_%E0%AE%95%E0%AE%9F%E0%AE%BF" title="பாம்புக் கடி – Tamil" lang="ta" hreflang="ta" data-title="பாம்புக் கடி" data-language-autonym="தமிழ்" data-language-local-name="Tamil" class="interlanguage-link-target"><span>தமிழ்</span></a></li><li class="interlanguage-link interwiki-te mw-list-item"><a href="https://te.wikipedia.org/wiki/%E0%B0%AA%E0%B0%BE%E0%B0%AE%E0%B1%81%E0%B0%95%E0%B0%BE%E0%B0%9F%E0%B1%81" title="పాముకాటు – Telugu" lang="te" hreflang="te" data-title="పాముకాటు" data-language-autonym="తెలుగు" data-language-local-name="Telugu" class="interlanguage-link-target"><span>తెలుగు</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Y%C4%B1lan_%C4%B1s%C4%B1r%C4%B1%C4%9F%C4%B1" title="Yılan ısırığı – Turkish" lang="tr" hreflang="tr" data-title="Yılan ısırığı" data-language-autonym="Türkçe" data-language-local-name="Turkish" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%A3%D0%BA%D1%83%D1%81_%D0%B7%D0%BC%D1%96%D1%97" title="Укус змії – Ukrainian" lang="uk" hreflang="uk" data-title="Укус змії" data-language-autonym="Українська" data-language-local-name="Ukrainian" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-ur mw-list-item"><a href="https://ur.wikipedia.org/wiki/%D9%85%D8%A7%D8%B1_%DA%AF%D8%B2%DB%8C%D8%AF%DA%AF%DB%8C" title="مار گزیدگی – Urdu" lang="ur" hreflang="ur" data-title="مار گزیدگی" data-language-autonym="اردو" data-language-local-name="Urdu" class="interlanguage-link-target"><span>اردو</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/R%E1%BA%AFn_c%E1%BA%AFn" title="Rắn cắn – Vietnamese" lang="vi" hreflang="vi" data-title="Rắn cắn" data-language-autonym="Tiếng Việt" data-language-local-name="Vietnamese" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-zh-yue mw-list-item"><a href="https://zh-yue.wikipedia.org/wiki/%E8%9B%87%E5%92%AC%E5%82%B7" title="蛇咬傷 – Cantonese" lang="yue" hreflang="yue" data-title="蛇咬傷" data-language-autonym="粵語" data-language-local-name="Cantonese" class="interlanguage-link-target"><span>粵語</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E8%9B%87%E5%92%AC%E5%82%B7" title="蛇咬傷 – Chinese" lang="zh" hreflang="zh" data-title="蛇咬傷" data-language-autonym="中文" data-language-local-name="Chinese" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q68854#sitelinks-wikipedia" title="Edit interlanguage links" class="wbc-editpage">Edit links</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Namespaces"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet 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</div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">From Wikipedia, the free encyclopedia</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Injury caused by bite from snakes</div> <style data-mw-deduplicate="TemplateStyles:r1236090951">.mw-parser-output .hatnote{font-style:italic}.mw-parser-output div.hatnote{padding-left:1.6em;margin-bottom:0.5em}.mw-parser-output .hatnote i{font-style:normal}.mw-parser-output .hatnote+link+.hatnote{margin-top:-0.5em}@media print{body.ns-0 .mw-parser-output .hatnote{display:none!important}}</style><div role="note" class="hatnote navigation-not-searchable">For other uses, see <a href="/wiki/Snakebite_(disambiguation)" class="mw-disambig" title="Snakebite (disambiguation)">Snakebite (disambiguation)</a>.</div> <p class="mw-empty-elt"> </p> <div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Medical condition</div><style data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox infobox-has-images-with-white-backgrounds"><tbody><tr><th colspan="2" class="infobox-above" style="background:#ccc">Snakebite</th></tr><tr><td colspan="2" class="infobox-full-data"><span class="mw-default-size" typeof="mw:File/Frameless"><a href="/wiki/File:Cobra_bite_in_Thailand_(image,_2023).jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/6/6f/Cobra_bite_in_Thailand_%28image%2C_2023%29.jpg/220px-Cobra_bite_in_Thailand_%28image%2C_2023%29.jpg" decoding="async" width="220" height="176" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/6f/Cobra_bite_in_Thailand_%28image%2C_2023%29.jpg/330px-Cobra_bite_in_Thailand_%28image%2C_2023%29.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/6f/Cobra_bite_in_Thailand_%28image%2C_2023%29.jpg/440px-Cobra_bite_in_Thailand_%28image%2C_2023%29.jpg 2x" data-file-width="3024" data-file-height="2419" /></a></span></td></tr><tr><td colspan="2" class="infobox-full-data">A <a href="/wiki/Cobra" title="Cobra">cobra</a> bite on the foot of a girl in <a href="/wiki/Thailand" title="Thailand">Thailand</a></td></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/Medical_specialty" title="Medical specialty">Specialty</a></th><td class="infobox-data"><a href="/wiki/Emergency_medicine" title="Emergency medicine">Emergency medicine</a></td></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/Signs_and_symptoms" title="Signs and symptoms">Symptoms</a></th><td class="infobox-data">Two <a href="/wiki/Puncture_wound" class="mw-redirect" title="Puncture wound">puncture wounds</a>, <a href="/wiki/Redness" class="mw-redirect" title="Redness">redness</a>, <a href="/wiki/Edema" title="Edema">swelling</a>, severe pain at the area<sup id="cite_ref-CDC2012_1-0" class="reference"><a href="#cite_note-CDC2012-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Gold2002_2-0" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup></td></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/Complication_(medicine)" title="Complication (medicine)">Complications</a></th><td class="infobox-data"><a href="/wiki/Hemorrhage" class="mw-redirect" title="Hemorrhage">Bleeding</a>, <a href="/wiki/Kidney_failure" title="Kidney failure">kidney failure</a>, <a href="/wiki/Anaphylaxis" title="Anaphylaxis">severe allergic reaction</a>, <a href="/wiki/Necrosis" title="Necrosis">tissue death</a> around the bite, breathing problems, <a href="/wiki/Amputation" title="Amputation">amputation</a>, <a href="/wiki/Envenomation" title="Envenomation">envenomation</a><sup id="cite_ref-CDC2012_1-1" class="reference"><a href="#cite_note-CDC2012-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-WHO2015_3-0" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup></td></tr><tr><th scope="row" class="infobox-label">Causes</th><td class="infobox-data"><a href="/wiki/Snakes" class="mw-redirect" title="Snakes">Snakes</a><sup id="cite_ref-CDC2012_1-2" class="reference"><a href="#cite_note-CDC2012-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup></td></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/Risk_factor" title="Risk factor">Risk factors</a></th><td class="infobox-data">Working outside with one's hands (<a href="/wiki/Farming" class="mw-redirect" title="Farming">farming</a>, <a href="/wiki/Forestry" title="Forestry">forestry</a>, construction);<sup id="cite_ref-CDC2012_1-3" class="reference"><a href="#cite_note-CDC2012-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-WHO2015_3-1" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> harassment;<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">&#91;</span>4<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">&#91;</span>5<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/Drunkenness" class="mw-redirect" title="Drunkenness">drunkenness</a><sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">&#91;</span>6<span class="cite-bracket">&#93;</span></a></sup></td></tr><tr><th scope="row" class="infobox-label">Prevention</th><td class="infobox-data"><a href="/w/index.php?title=Protective_footwear&amp;action=edit&amp;redlink=1" class="new" title="Protective footwear (page does not exist)">Protective footwear</a>, avoiding areas where snakes live, not handling snakes<sup id="cite_ref-CDC2012_1-4" class="reference"><a href="#cite_note-CDC2012-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup></td></tr><tr><th scope="row" class="infobox-label">Treatment</th><td class="infobox-data">Washing the wound with soap and water, <a href="/wiki/Antivenom" title="Antivenom">antivenom</a><sup id="cite_ref-CDC2012_1-5" class="reference"><a href="#cite_note-CDC2012-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-WHONeg_7-0" class="reference"><a href="#cite_note-WHONeg-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup></td></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/Prognosis" title="Prognosis">Prognosis</a></th><td class="infobox-data">Depends on type of snake<sup id="cite_ref-Marx2010_8-0" class="reference"><a href="#cite_note-Marx2010-8"><span class="cite-bracket">&#91;</span>8<span class="cite-bracket">&#93;</span></a></sup></td></tr><tr><th scope="row" class="infobox-label">Frequency</th><td class="infobox-data">Up to 5 million a year<sup id="cite_ref-WHO2015_3-2" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup></td></tr><tr><th scope="row" class="infobox-label">Deaths</th><td class="infobox-data">94,000–125,000 per year<sup id="cite_ref-WHO2015_3-3" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup></td></tr></tbody></table><style data-mw-deduplicate="TemplateStyles:r1236303919">@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-has-images-with-white-backgrounds img{background:white}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-has-images-with-white-backgrounds img{background:white}}</style> <p>A <b>snakebite</b> is an injury caused by the bite of a snake, especially a <a href="/wiki/Venomous_snake" title="Venomous snake">venomous snake</a>.<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">&#91;</span>9<span class="cite-bracket">&#93;</span></a></sup> A common sign of a bite from a venomous snake is the presence of two <a href="/wiki/Puncture_wound" class="mw-redirect" title="Puncture wound">puncture wounds</a> from the animal's <a href="/wiki/Fang" title="Fang">fangs</a>.<sup id="cite_ref-CDC2012_1-6" class="reference"><a href="#cite_note-CDC2012-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> Sometimes <a href="/wiki/Envenomation" title="Envenomation">venom injection from the bite</a> may occur.<sup id="cite_ref-WHO2015_3-4" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> This may result in redness, swelling, and severe pain at the area, which may take up to an hour to appear.<sup id="cite_ref-CDC2012_1-7" class="reference"><a href="#cite_note-CDC2012-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Gold2002_2-1" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/Vomiting" title="Vomiting">Vomiting</a>, blurred vision, tingling of the limbs, and sweating may result.<sup id="cite_ref-CDC2012_1-8" class="reference"><a href="#cite_note-CDC2012-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Gold2002_2-2" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> Most bites are on the hands, arms, or legs.<sup id="cite_ref-Gold2002_2-3" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">&#91;</span>10<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/Fear" title="Fear">Fear</a> following a bite is common with symptoms of a <a href="/wiki/Tachycardia" title="Tachycardia">racing heart</a> and <a href="/wiki/Dizziness" title="Dizziness">feeling faint</a>.<sup id="cite_ref-Gold2002_2-4" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> The <a href="/wiki/Venom" title="Venom">venom</a> may cause <a href="/wiki/Hemorrhage" class="mw-redirect" title="Hemorrhage">bleeding</a>, <a href="/wiki/Kidney_failure" title="Kidney failure">kidney failure</a>, a <a href="/wiki/Anaphylaxis" title="Anaphylaxis">severe allergic reaction</a>, <a href="/wiki/Necrosis" title="Necrosis">tissue death</a> around the bite, or breathing problems.<sup id="cite_ref-CDC2012_1-9" class="reference"><a href="#cite_note-CDC2012-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-WHO2015_3-5" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> Bites may result in the <a href="/wiki/Amputation" title="Amputation">loss of a limb</a> or other <a href="/wiki/Chronic_condition" title="Chronic condition">chronic problems</a> or even death.<sup id="cite_ref-Healthline_Media_UK_Ltd_11-0" class="reference"><a href="#cite_note-Healthline_Media_UK_Ltd-11"><span class="cite-bracket">&#91;</span>11<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-WHO2015_3-6" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> </p><p>The outcome depends on the type of snake, the area of the body bitten, the amount of <a href="/wiki/Snake_venom" title="Snake venom">snake venom</a> injected, the general health of the person bitten, and whether or not anti-venom serum has been administered by a doctor in a timely manner.<sup id="cite_ref-Healthline_Media_UK_Ltd_11-1" class="reference"><a href="#cite_note-Healthline_Media_UK_Ltd-11"><span class="cite-bracket">&#91;</span>11<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Marx2010_8-1" class="reference"><a href="#cite_note-Marx2010-8"><span class="cite-bracket">&#91;</span>8<span class="cite-bracket">&#93;</span></a></sup> Problems are often more severe in children than adults, due to their smaller size.<sup id="cite_ref-WHO2015_3-7" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">&#91;</span>12<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-WHOantivenoms_13-0" class="reference"><a href="#cite_note-WHOantivenoms-13"><span class="cite-bracket">&#91;</span>13<span class="cite-bracket">&#93;</span></a></sup> Allergic reactions to snake venom can further complicate outcomes and can include <a href="/wiki/Anaphylaxis" title="Anaphylaxis">anaphylaxis</a>, requiring additional treatment and in some cases resulting in death.<sup id="cite_ref-Healthline_Media_UK_Ltd_11-2" class="reference"><a href="#cite_note-Healthline_Media_UK_Ltd-11"><span class="cite-bracket">&#91;</span>11<span class="cite-bracket">&#93;</span></a></sup> </p><p>Snakes bite both as a method of hunting and as a means of protection.<sup id="cite_ref-Kast2008_14-0" class="reference"><a href="#cite_note-Kast2008-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/Risk_factor" title="Risk factor">Risk factors</a> for bites include working outside with one's hands such as in <a href="/wiki/Farming" class="mw-redirect" title="Farming">farming</a>, <a href="/wiki/Forestry" title="Forestry">forestry</a>, and construction.<sup id="cite_ref-CDC2012_1-10" class="reference"><a href="#cite_note-CDC2012-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-WHO2015_3-8" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> Snakes commonly involved in envenomations include <a href="/wiki/Elapid" class="mw-redirect" title="Elapid">elapids</a> (such as <a href="/wiki/Krait" class="mw-redirect" title="Krait">kraits</a>, <a href="/wiki/Cobra" title="Cobra">cobras</a> and <a href="/wiki/Mamba" title="Mamba">mambas</a>), <a href="/wiki/Viper" title="Viper">vipers</a>, and <a href="/wiki/Sea_snake" title="Sea snake">sea snakes</a>.<sup id="cite_ref-WHONeg_7-1" class="reference"><a href="#cite_note-WHONeg-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup> The majority of snake species do not have venom and kill their prey by <a href="/wiki/Constriction" title="Constriction">constriction</a> (squeezing them).<sup id="cite_ref-Gold2002_2-5" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> Venomous snakes can be found on every continent except <a href="/wiki/Antarctica" title="Antarctica">Antarctica</a>.<sup id="cite_ref-Kast2008_14-1" class="reference"><a href="#cite_note-Kast2008-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup> Determining the type of snake that caused a bite is often not possible.<sup id="cite_ref-WHONeg_7-2" class="reference"><a href="#cite_note-WHONeg-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup> The <a href="/wiki/World_Health_Organization" title="World Health Organization">World Health Organization</a> says snakebites are a "neglected <a href="/wiki/Public_health_issue" class="mw-redirect" title="Public health issue">public health issue</a> in many tropical and subtropical countries",<sup id="cite_ref-WHOantivenoms_13-1" class="reference"><a href="#cite_note-WHOantivenoms-13"><span class="cite-bracket">&#91;</span>13<span class="cite-bracket">&#93;</span></a></sup> and in 2017, the WHO categorized snakebite envenomation as a <a href="/wiki/Neglected_Tropical_Disease" class="mw-redirect" title="Neglected Tropical Disease">Neglected Tropical Disease</a> (Category A). The WHO also estimates that between 4.5 and 5.4 million people are bitten each year, and of those figures, 40–50% develop some kind of clinical illness as a result.<sup id="cite_ref-Langley2020_15-0" class="reference"><a href="#cite_note-Langley2020-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup> Furthermore, the death toll from such an injury could range between 80,000 and 130,000 people per year.<sup id="cite_ref-16" class="reference"><a href="#cite_note-16"><span class="cite-bracket">&#91;</span>16<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Langley2020_15-1" class="reference"><a href="#cite_note-Langley2020-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup> The purpose was to encourage research, expand the accessibility of antivenoms, and improve snakebite management in "<a href="/wiki/Developing_country" title="Developing country">developing countries</a>".<sup id="cite_ref-17" class="reference"><a href="#cite_note-17"><span class="cite-bracket">&#91;</span>17<span class="cite-bracket">&#93;</span></a></sup> </p><p>Prevention of snake bites can involve wearing protective footwear, avoiding areas where snakes live, and not handling snakes.<sup id="cite_ref-CDC2012_1-11" class="reference"><a href="#cite_note-CDC2012-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> Treatment partly depends on the type of snake.<sup id="cite_ref-CDC2012_1-12" class="reference"><a href="#cite_note-CDC2012-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> Washing the wound with soap and water and holding the limb still is recommended.<sup id="cite_ref-CDC2012_1-13" class="reference"><a href="#cite_note-CDC2012-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-WHONeg_7-3" class="reference"><a href="#cite_note-WHONeg-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup> Trying to suck out the venom, cutting the wound with a knife, or using a <a href="/wiki/Tourniquet" title="Tourniquet">tourniquet</a> is not recommended.<sup id="cite_ref-CDC2012_1-14" class="reference"><a href="#cite_note-CDC2012-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/Antivenom" title="Antivenom">Antivenom</a> is effective at preventing death from bites; however, antivenoms frequently have <a href="/wiki/Side_effect" title="Side effect">side effects</a>.<sup id="cite_ref-WHO2015_3-9" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Gutierrez2007_18-0" class="reference"><a href="#cite_note-Gutierrez2007-18"><span class="cite-bracket">&#91;</span>18<span class="cite-bracket">&#93;</span></a></sup> The type of antivenom needed depends on the type of snake involved.<sup id="cite_ref-WHONeg_7-4" class="reference"><a href="#cite_note-WHONeg-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup> When the type of snake is unknown, antivenom is often given based on the types known to be in the area.<sup id="cite_ref-WHONeg_7-5" class="reference"><a href="#cite_note-WHONeg-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup> In some areas of the world, getting the right type of antivenom is difficult and this partly contributes to why they sometimes do not work.<sup id="cite_ref-WHO2015_3-10" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> An additional issue is the cost of these medications.<sup id="cite_ref-WHO2015_3-11" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> Antivenom has little effect on the area around the bite itself.<sup id="cite_ref-WHONeg_7-6" class="reference"><a href="#cite_note-WHONeg-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/Mechanical_ventilation" title="Mechanical ventilation">Supporting the person's breathing</a> is sometimes also required.<sup id="cite_ref-WHONeg_7-7" class="reference"><a href="#cite_note-WHONeg-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup> </p><p>The number of venomous snakebites that occur each year may be as high as five million.<sup id="cite_ref-WHO2015_3-12" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> They result in about 2.5 million envenomations and 20,000 to 125,000 deaths.<sup id="cite_ref-WHO2015_3-13" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Kast2008_14-2" class="reference"><a href="#cite_note-Kast2008-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup> The frequency and severity of bites vary greatly among different parts of the world.<sup id="cite_ref-Kast2008_14-3" class="reference"><a href="#cite_note-Kast2008-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup> They occur most commonly in <a href="/wiki/Africa" title="Africa">Africa</a>, <a href="/wiki/Asia" title="Asia">Asia</a>, and <a href="/wiki/Latin_America" title="Latin America">Latin America</a>,<sup id="cite_ref-WHO2015_3-14" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> with rural areas more greatly affected.<sup id="cite_ref-WHO2015_3-15" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-WHOantivenoms_13-2" class="reference"><a href="#cite_note-WHOantivenoms-13"><span class="cite-bracket">&#91;</span>13<span class="cite-bracket">&#93;</span></a></sup> Deaths are relatively rare in <a href="/wiki/Australia" title="Australia">Australia</a>, <a href="/wiki/Europe" title="Europe">Europe</a> and <a href="/wiki/North_America" title="North America">North America</a>.<sup id="cite_ref-Kast2008_14-4" class="reference"><a href="#cite_note-Kast2008-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Gutierrez2007_18-1" class="reference"><a href="#cite_note-Gutierrez2007-18"><span class="cite-bracket">&#91;</span>18<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Chippaux1998_19-0" class="reference"><a href="#cite_note-Chippaux1998-19"><span class="cite-bracket">&#91;</span>19<span class="cite-bracket">&#93;</span></a></sup> For example, in the United States, about seven to eight thousand people per year are bitten by venomous snakes (about one in 40 thousand people) and about five people die (about one death per 65 million people).<sup id="cite_ref-CDC2012_1-15" class="reference"><a href="#cite_note-CDC2012-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> </p> <style data-mw-deduplicate="TemplateStyles:r886046785">.mw-parser-output .toclimit-2 .toclevel-1 ul,.mw-parser-output .toclimit-3 .toclevel-2 ul,.mw-parser-output .toclimit-4 .toclevel-3 ul,.mw-parser-output .toclimit-5 .toclevel-4 ul,.mw-parser-output .toclimit-6 .toclevel-5 ul,.mw-parser-output .toclimit-7 .toclevel-6 ul{display:none}</style><div class="toclimit-3"><meta property="mw:PageProp/toc" /></div> <div class="mw-heading mw-heading2"><h2 id="Signs_and_symptoms">Signs and symptoms</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=1" title="Edit section: Signs and symptoms"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/File:Snake_bite_symptoms.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a8/Snake_bite_symptoms.png/330px-Snake_bite_symptoms.png" decoding="async" width="310" height="308" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a8/Snake_bite_symptoms.png/500px-Snake_bite_symptoms.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a8/Snake_bite_symptoms.png/960px-Snake_bite_symptoms.png 2x" data-file-width="1826" data-file-height="1817" /></a><figcaption>The most common symptoms of any kind of snake envenomation.<sup id="cite_ref-MedlinePlus_20-0" class="reference"><a href="#cite_note-MedlinePlus-20"><span class="cite-bracket">&#91;</span>20<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-21" class="reference"><a href="#cite_note-21"><span class="cite-bracket">&#91;</span>21<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-22" class="reference"><a href="#cite_note-22"><span class="cite-bracket">&#91;</span>22<span class="cite-bracket">&#93;</span></a></sup> However, there is vast variation in symptoms between bites from different types of snakes.<sup id="cite_ref-MedlinePlus_20-1" class="reference"><a href="#cite_note-MedlinePlus-20"><span class="cite-bracket">&#91;</span>20<span class="cite-bracket">&#93;</span></a></sup></figcaption></figure> <p>The most common first symptom of all snakebites is an overwhelming fear, which may contribute to other symptoms, and may include <a href="/wiki/Nausea" title="Nausea">nausea</a> and <a href="/wiki/Vomiting" title="Vomiting">vomiting</a>, <a href="/wiki/Diarrhea" title="Diarrhea">diarrhea</a>, <a href="/wiki/Vertigo_(medical)" class="mw-redirect" title="Vertigo (medical)">vertigo</a>, <a href="/wiki/Fainting" class="mw-redirect" title="Fainting">fainting</a>, <a href="/wiki/Tachycardia" title="Tachycardia">tachycardia</a>, and cold, clammy skin.<sup id="cite_ref-Gold2002_2-6" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Kitchens1987_23-0" class="reference"><a href="#cite_note-Kitchens1987-23"><span class="cite-bracket">&#91;</span>23<span class="cite-bracket">&#93;</span></a></sup> Snake bites can have a variety of different signs and symptoms depending on their species.<sup id="cite_ref-Healthline_Media_UK_Ltd_11-3" class="reference"><a href="#cite_note-Healthline_Media_UK_Ltd-11"><span class="cite-bracket">&#91;</span>11<span class="cite-bracket">&#93;</span></a></sup> </p><p><a href="/wiki/Dry_bite" title="Dry bite">Dry snakebites</a> and those inflicted by a non-venomous species may still cause severe injury. The bite may become infected from the snake's saliva. The fangs sometimes harbor pathogenic microbial organisms, including <i><a href="/wiki/Clostridium_tetani" title="Clostridium tetani">Clostridium tetani</a></i>, and may require an updated tetanus immunization.<sup id="cite_ref-24" class="reference"><a href="#cite_note-24"><span class="cite-bracket">&#91;</span>24<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Langley2020_15-2" class="reference"><a href="#cite_note-Langley2020-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup> </p><p>Most snakebites, from either a venomous or a non-venomous snake, will have some type of local effect.<sup id="cite_ref-Online_Khabar_25-0" class="reference"><a href="#cite_note-Online_Khabar-25"><span class="cite-bracket">&#91;</span>25<span class="cite-bracket">&#93;</span></a></sup> Minor pain and <a href="/wiki/Erythema" title="Erythema">redness</a> occur in over 90 percent of cases, although this varies depending on the site.<sup id="cite_ref-Gold2002_2-7" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> Bites by <a href="/wiki/Viper_(animal)" class="mw-redirect" title="Viper (animal)">vipers</a> and some <a href="/wiki/Cobra" title="Cobra">cobras</a> may be extremely painful, with the local tissue sometimes becoming tender and severely <a href="/wiki/Edema" title="Edema">swollen</a> within five minutes.<sup id="cite_ref-Gutierrez2007_18-2" class="reference"><a href="#cite_note-Gutierrez2007-18"><span class="cite-bracket">&#91;</span>18<span class="cite-bracket">&#93;</span></a></sup> This area may also bleed and blister and may lead to tissue <a href="/wiki/Necrosis" title="Necrosis">necrosis</a>. Other common initial symptoms of <a href="/wiki/Pit_viper" title="Pit viper">pit viper</a> and <a href="/wiki/Viper_(animal)" class="mw-redirect" title="Viper (animal)">viper</a> bites include lethargy, bleeding, weakness, nausea, and vomiting.<sup id="cite_ref-Gold2002_2-8" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Gutierrez2007_18-3" class="reference"><a href="#cite_note-Gutierrez2007-18"><span class="cite-bracket">&#91;</span>18<span class="cite-bracket">&#93;</span></a></sup> Symptoms may become more life-threatening over time, developing into <a href="/wiki/Hypotension" title="Hypotension">hypotension</a>, <a href="/wiki/Tachypnea" title="Tachypnea">tachypnea</a>, severe tachycardia, severe internal bleeding, altered <a href="/wiki/Sensorium" title="Sensorium">sensorium</a>, <a href="/wiki/Kidney_failure" title="Kidney failure">kidney failure</a>, and <a href="/wiki/Respiratory_failure" title="Respiratory failure">respiratory failure</a>.<sup id="cite_ref-Gold2002_2-9" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Gutierrez2007_18-4" class="reference"><a href="#cite_note-Gutierrez2007-18"><span class="cite-bracket">&#91;</span>18<span class="cite-bracket">&#93;</span></a></sup> </p><p>Bites by some snakes, such as the <a href="/wiki/Kraits" class="mw-redirect" title="Kraits">kraits</a>, <a href="/wiki/Coral_snake" title="Coral snake">coral snake</a>, <a href="/wiki/Mojave_rattlesnake" class="mw-redirect" title="Mojave rattlesnake">Mojave rattlesnake</a>, and the <a href="/wiki/Crotalus_mitchellii" title="Crotalus mitchellii">speckled rattlesnake</a>, may cause little or no pain, despite their serious and potentially life-threatening venom.<sup id="cite_ref-Gold2002_2-10" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> Some people report experiencing a "rubbery", "minty", or "metallic" taste after being bitten by certain species of rattlesnake.<sup id="cite_ref-Gold2002_2-11" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/Spitting_cobra" title="Spitting cobra">Spitting cobras</a> and <a href="/wiki/Rinkhals" title="Rinkhals">rinkhalses</a> can spit venom in a person's eyes. This results in immediate pain, <a href="/wiki/Ophthalmoparesis" title="Ophthalmoparesis">ophthalmoparesis</a>, and sometimes <a href="/wiki/Blindness" class="mw-redirect" title="Blindness">blindness</a>.<sup id="cite_ref-Warrell1976_26-0" class="reference"><a href="#cite_note-Warrell1976-26"><span class="cite-bracket">&#91;</span>26<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Ismail1993_27-0" class="reference"><a href="#cite_note-Ismail1993-27"><span class="cite-bracket">&#91;</span>27<span class="cite-bracket">&#93;</span></a></sup> </p> <figure class="mw-default-size mw-halign-left" typeof="mw:File/Thumb"><a href="/wiki/File:Tissue_necrosis_following_bite_from_Bothrops_asper_PLoS_Medicine.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4f/Tissue_necrosis_following_bite_from_Bothrops_asper_PLoS_Medicine.jpg/170px-Tissue_necrosis_following_bite_from_Bothrops_asper_PLoS_Medicine.jpg" decoding="async" width="170" height="316" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4f/Tissue_necrosis_following_bite_from_Bothrops_asper_PLoS_Medicine.jpg/255px-Tissue_necrosis_following_bite_from_Bothrops_asper_PLoS_Medicine.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4f/Tissue_necrosis_following_bite_from_Bothrops_asper_PLoS_Medicine.jpg/340px-Tissue_necrosis_following_bite_from_Bothrops_asper_PLoS_Medicine.jpg 2x" data-file-width="784" data-file-height="1459" /></a><figcaption>Severe <a href="/wiki/Tissue_necrosis" class="mw-redirect" title="Tissue necrosis">tissue necrosis</a> following <i><a href="/wiki/Bothrops_asper" title="Bothrops asper">Bothrops asper</a></i> envenomation that required <a href="/wiki/Amputation" title="Amputation">amputation</a> above the knee. The person was an 11-year-old boy, bitten two weeks earlier in <a href="/wiki/Ecuador" title="Ecuador">Ecuador</a>, but treated only with <a href="/wiki/Antibiotic" title="Antibiotic">antibiotics</a>.<sup id="cite_ref-Gutierrez2006_28-0" class="reference"><a href="#cite_note-Gutierrez2006-28"><span class="cite-bracket">&#91;</span>28<span class="cite-bracket">&#93;</span></a></sup></figcaption></figure> <p>Some Australian elapids and most viper envenomations will cause <a href="/wiki/Coagulopathy" title="Coagulopathy">coagulopathy</a>, sometimes so severe that a person may bleed spontaneously from the mouth, nose, and even old, seemingly healed wounds.<sup id="cite_ref-Gutierrez2007_18-5" class="reference"><a href="#cite_note-Gutierrez2007-18"><span class="cite-bracket">&#91;</span>18<span class="cite-bracket">&#93;</span></a></sup> Internal organs may bleed, including the brain and intestines,<sup id="cite_ref-Cunha2021_29-0" class="reference"><a href="#cite_note-Cunha2021-29"><span class="cite-bracket">&#91;</span>29<span class="cite-bracket">&#93;</span></a></sup> and <a href="/wiki/Ecchymosis" class="mw-redirect" title="Ecchymosis">ecchymosis</a> (bruising) of the skin is often seen.<sup id="cite_ref-SmallAnimalToxicology_30-0" class="reference"><a href="#cite_note-SmallAnimalToxicology-30"><span class="cite-bracket">&#91;</span>30<span class="cite-bracket">&#93;</span></a></sup> </p><p>The venom of elapids, including <a href="/wiki/Sea_snakes" class="mw-redirect" title="Sea snakes">sea snakes</a>, <a href="/wiki/Bungarus" title="Bungarus">kraits</a>, <a href="/wiki/Naja" title="Naja">cobras</a>, <a href="/wiki/Ophiophagus_hannah" class="mw-redirect" title="Ophiophagus hannah">king cobra</a>, <a href="/wiki/Dendroaspis" class="mw-redirect" title="Dendroaspis">mambas</a>, and many Australian species, contains toxins which attack the nervous system, causing <a href="/wiki/Neurotoxicity" title="Neurotoxicity">neurotoxicity</a>.<sup id="cite_ref-Gold2002_2-12" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Gutierrez2007_18-6" class="reference"><a href="#cite_note-Gutierrez2007-18"><span class="cite-bracket">&#91;</span>18<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Phillips2002_31-0" class="reference"><a href="#cite_note-Phillips2002-31"><span class="cite-bracket">&#91;</span>31<span class="cite-bracket">&#93;</span></a></sup> The person may present with strange disturbances to their vision, including blurriness. <a href="/wiki/Paresthesia" title="Paresthesia">Paresthesia</a> throughout the body, as well as difficulty in speaking and breathing, may be reported.<sup id="cite_ref-Gold2002_2-13" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> Nervous system problems will cause a huge array of symptoms, and those provided here are not exhaustive. If not treated immediately they may die from <a href="/wiki/Respiratory_failure" title="Respiratory failure">respiratory failure</a>.<sup id="cite_ref-ManagementofRespiratoryFailure_32-0" class="reference"><a href="#cite_note-ManagementofRespiratoryFailure-32"><span class="cite-bracket">&#91;</span>32<span class="cite-bracket">&#93;</span></a></sup> </p><p>Venom emitted from some types of cobras, almost all vipers, and some sea snakes cause <a href="/wiki/Necrosis" title="Necrosis">necrosis</a> of muscle tissue.<sup id="cite_ref-Gutierrez2007_18-7" class="reference"><a href="#cite_note-Gutierrez2007-18"><span class="cite-bracket">&#91;</span>18<span class="cite-bracket">&#93;</span></a></sup> Muscle tissue will begin to die throughout the body, a condition known as <a href="/wiki/Rhabdomyolysis" title="Rhabdomyolysis">rhabdomyolysis</a>. Rhabdomyolysis can result in damage to the kidneys as a result of myoglobin accumulation in the renal tubules. This, coupled with <a href="/wiki/Hypotension" title="Hypotension">hypotension</a>, can lead to <a href="/wiki/Acute_kidney_injury" title="Acute kidney injury">acute kidney injury</a>, and, if left untreated, eventually death.<sup id="cite_ref-Gutierrez2007_18-8" class="reference"><a href="#cite_note-Gutierrez2007-18"><span class="cite-bracket">&#91;</span>18<span class="cite-bracket">&#93;</span></a></sup> </p><p>Snakebite is also known to cause depression and post-traumatic stress disorder in a high proportion of people who survive.<sup id="cite_ref-33" class="reference"><a href="#cite_note-33"><span class="cite-bracket">&#91;</span>33<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Cause">Cause</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=2" title="Edit section: Cause"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951" /><div role="note" class="hatnote navigation-not-searchable">See also: <a href="/wiki/List_of_dangerous_snakes" title="List of dangerous snakes">List of dangerous snakes</a></div> <p>In the developing world most snakebites occur in those who work outside such as farmers, hunters, and fishermen. They often happen when a person steps on the snake or approaches it too closely. In the United States and Europe snakebites most commonly occur in those who keep them as pets.<sup id="cite_ref-Brut2013_34-0" class="reference"><a href="#cite_note-Brut2013-34"><span class="cite-bracket">&#91;</span>34<span class="cite-bracket">&#93;</span></a></sup> </p><p>The type of snake that most often delivers serious bites depends on the region of the world. In Africa, it is <a href="/wiki/Mamba" title="Mamba">mambas</a>, <a href="/wiki/Egyptian_cobra" title="Egyptian cobra">Egyptian cobras</a>, <a href="/wiki/Bitis_arietans" class="mw-redirect" title="Bitis arietans">puff adders</a>, and <a href="/wiki/Carpet_viper" class="mw-redirect" title="Carpet viper">carpet vipers</a>. In the Middle East, it is carpet vipers and <a href="/wiki/Elapid" class="mw-redirect" title="Elapid">elapids</a>. In <a href="/wiki/Latin_America" title="Latin America">Latin America</a>, it is snakes of the <i><a href="/wiki/Bothrops" title="Bothrops">Bothrops</a></i> and <i><a href="/wiki/Crotalus" title="Crotalus">Crotalus</a></i> types, the latter including <a href="/wiki/Rattlesnake" title="Rattlesnake">rattlesnakes</a>.<sup id="cite_ref-Brut2013_34-1" class="reference"><a href="#cite_note-Brut2013-34"><span class="cite-bracket">&#91;</span>34<span class="cite-bracket">&#93;</span></a></sup> In North America, rattlesnakes are the primary concern, and up to 95% of all snakebite-related deaths in the United States are attributed to the <a href="/wiki/Crotalus_atrox" class="mw-redirect" title="Crotalus atrox">western</a> and <a href="/wiki/Crotalus_adamanteus" class="mw-redirect" title="Crotalus adamanteus">eastern diamondback</a> rattlesnakes.<sup id="cite_ref-Gold2002_2-14" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> The greatest number of bites are inflicted on the hands.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#91;<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (April 2024)">citation needed</span></a></i>&#93;</sup> People get bitten by handling snakes or in the outdoors by putting their hands on the wrong places. The next largest number of bites occur on the ankles, as snakes are often hidden or camouflaged extremely well to fend off predators. Most bite victims are bitten by surprise, and it is a comfortable fiction that rattlesnakes always forewarn their bite victims - often the bite is the first indication a snake is near. Since most venomous snakes move about during the dawn dusk or night, one may expect more encounters during the early morning or late afternoon, though many species such as the Western Diamondback may be encountered at any time of day and in fact most bites occur during the month of April when both snakes and humans are out and about and encounter one another hiking, in yards, or on pathways. Children playing within short distances of their homes crawl under porches, jump into bushes, pull boards of wood from a pile and are bitten. Most however occur when people handle rattlesnakes.<sup id="cite_ref-35" class="reference"><a href="#cite_note-35"><span class="cite-bracket">&#91;</span>35<span class="cite-bracket">&#93;</span></a></sup> In South Asia, it was previously believed that <a href="/wiki/Indian_cobra" title="Indian cobra">Indian cobras</a>, <a href="/wiki/Common_krait" title="Common krait">common kraits</a>, <a href="/wiki/Russell%27s_viper" title="Russell&#39;s viper">Russell's viper</a>, and carpet vipers were the most dangerous; other snakes, however, may also cause significant problems in this area of the world.<sup id="cite_ref-Brut2013_34-2" class="reference"><a href="#cite_note-Brut2013-34"><span class="cite-bracket">&#91;</span>34<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Pathophysiology">Pathophysiology</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=3" title="Edit section: Pathophysiology"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Since <a href="/wiki/Envenomation" title="Envenomation">envenomation</a> is completely voluntary, all venomous snakes are capable of biting without injecting venom into a person. Snakes may deliver such a "<a href="/wiki/Dry_bite" title="Dry bite">dry bite</a>" rather than waste their venom on a creature too large for them to eat, a behaviour called <a href="/wiki/Venom_metering" class="mw-redirect" title="Venom metering">venom metering</a>.<sup id="cite_ref-Young2002_36-0" class="reference"><a href="#cite_note-Young2002-36"><span class="cite-bracket">&#91;</span>36<span class="cite-bracket">&#93;</span></a></sup> However, the percentage of dry bites varies among species: 80 percent of bites inflicted by <a href="/wiki/Sea_snakes" class="mw-redirect" title="Sea snakes">sea snakes</a>, which are normally timid, do not result in envenomation,<sup id="cite_ref-Phillips2002_31-1" class="reference"><a href="#cite_note-Phillips2002-31"><span class="cite-bracket">&#91;</span>31<span class="cite-bracket">&#93;</span></a></sup> whereas for <a href="/wiki/Pit_viper" title="Pit viper">pit viper</a> bites the number is closer to 25 percent.<sup id="cite_ref-Gold2002_2-15" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> Furthermore, some snake <a href="/wiki/Genera" class="mw-redirect" title="Genera">genera</a>, such as <a href="/wiki/Rattlesnake" title="Rattlesnake">rattlesnakes</a>, can internally regulate the amount of venom they inject.<sup id="cite_ref-Young2001_37-0" class="reference"><a href="#cite_note-Young2001-37"><span class="cite-bracket">&#91;</span>37<span class="cite-bracket">&#93;</span></a></sup> There is a wide variance in the composition of venoms from one species of venomous snake to another. Some venoms may have their greatest effect on a victim's respiration or circulatory system. Others may damage or destroy tissues. This variance has imparted to the venom of each species a distinct chemistry. Sometimes antivenins have to be developed for individual species. For this reason, standard therapeutic measures will not work in all cases. </p><p>Some dry bites may also be the result of imprecise timing on the snake's part, as venom may be prematurely released before the fangs have penetrated the person.<sup id="cite_ref-Young2002_36-1" class="reference"><a href="#cite_note-Young2002-36"><span class="cite-bracket">&#91;</span>36<span class="cite-bracket">&#93;</span></a></sup> Even without venom, some snakes, particularly large constrictors such as those belonging to the <a href="/wiki/Boidae" title="Boidae">Boidae</a> and <a href="/wiki/Pythonidae" title="Pythonidae">Pythonidae</a> families, can deliver damaging bites; large specimens often cause severe <a href="/wiki/Laceration" class="mw-redirect" title="Laceration">lacerations</a>, or the snake itself pulls away, causing the flesh to be torn by the needle-sharp recurved teeth embedded in the person. While not as life-threatening as a bite from a venomous species, the bite can be at least temporarily debilitating and could lead to dangerous infections if improperly dealt with.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#91;<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (May 2021)">citation needed</span></a></i>&#93;</sup> </p><p>While most snakes must open their mouths before biting, African and Middle Eastern snakes belonging to the family <a href="/wiki/Atractaspididae" title="Atractaspididae">Atractaspididae</a> can fold their fangs to the side of their head without opening their mouth and jab a person.<sup id="cite_ref-Deufel2003_38-0" class="reference"><a href="#cite_note-Deufel2003-38"><span class="cite-bracket">&#91;</span>38<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Snake_venom">Snake venom</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=4" title="Edit section: Snake venom"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951" /><div role="note" class="hatnote navigation-not-searchable">Main articles: <a href="/wiki/Snake_venom" title="Snake venom">Snake venom</a> and <a href="/wiki/Venom-induced_consumption_coagulopathy" title="Venom-induced consumption coagulopathy">Venom-induced consumption coagulopathy</a></div> <p>It has been suggested that snakes evolved the mechanisms necessary for venom formation and delivery sometime during the <a href="/wiki/Miocene" title="Miocene">Miocene</a> epoch.<sup id="cite_ref-Jackson2003_39-0" class="reference"><a href="#cite_note-Jackson2003-39"><span class="cite-bracket">&#91;</span>39<span class="cite-bracket">&#93;</span></a></sup> During the mid-<a href="/wiki/Tertiary" title="Tertiary">Tertiary</a>, most snakes were large <a href="/wiki/Ambush_predator" title="Ambush predator">ambush predators</a> belonging to the superfamily <a href="/wiki/Henophidia" title="Henophidia">Henophidia</a>, which use constriction to kill their prey. As open grasslands replaced forested areas in parts of the world, some snake families evolved to become smaller and thus more agile. However, subduing and killing prey became more difficult for the smaller snakes, leading to the evolution of snake venom. The most likely hypothesis holds that venom glands evolved from specialized salivary glands. The venom itself evolved through the process of natural selection; it retained and emphasized the qualities that made it useful in killing or subduing prey. Today we can find various snake species in stages of this hypothesized development. There are the highly efficient envenoming machines - like the rattlesnakes - with large capacity venom storage, hollow fangs that swing into position immediately before the snake bites, and spare fangs ready to replace those damaged or lost.<sup id="cite_ref-40" class="reference"><a href="#cite_note-40"><span class="cite-bracket">&#91;</span>40<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Jackson2003_39-1" class="reference"><a href="#cite_note-Jackson2003-39"><span class="cite-bracket">&#91;</span>39<span class="cite-bracket">&#93;</span></a></sup> Other research on <a href="/wiki/Toxicofera" title="Toxicofera">Toxicofera</a>, a hypothetical <a href="/wiki/Clade" title="Clade">clade</a> thought to be ancestral to most living reptiles, suggests an earlier time frame for the evolution of snake venom, possibly to the order of tens of millions of years, during the <a href="/wiki/Late_Cretaceous" title="Late Cretaceous">Late Cretaceous</a>.<sup id="cite_ref-Fry2006_41-0" class="reference"><a href="#cite_note-Fry2006-41"><span class="cite-bracket">&#91;</span>41<span class="cite-bracket">&#93;</span></a></sup> </p><p>Snake venom is produced in modified <a href="/wiki/Parotid_gland" title="Parotid gland">parotid glands</a> normally responsible for secreting saliva. It is stored in structures called <a href="https://en.wiktionary.org/wiki/alveolus" class="extiw" title="wikt:alveolus">alveoli</a> behind the animal's eyes and ejected voluntarily through its hollow tubular <a href="/wiki/Fangs" class="mw-redirect" title="Fangs">fangs</a>.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#91;<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (March 2023)">citation needed</span></a></i>&#93;</sup> </p><p>Venom in many snakes, such as pit vipers, affects virtually every organ system in the human body and can be a combination of many toxins, including <a href="/wiki/Cytotoxins" class="mw-redirect" title="Cytotoxins">cytotoxins</a>, <a href="/wiki/Hemotoxins" class="mw-redirect" title="Hemotoxins">hemotoxins</a>, <a href="/wiki/Neurotoxins" class="mw-redirect" title="Neurotoxins">neurotoxins</a>, and <a href="/wiki/Myotoxin" title="Myotoxin">myotoxins</a>, allowing for an enormous variety of symptoms.<sup id="cite_ref-Gold2002_2-16" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Russell1980a_42-0" class="reference"><a href="#cite_note-Russell1980a-42"><span class="cite-bracket">&#91;</span>42<span class="cite-bracket">&#93;</span></a></sup> Snake venom may cause <a href="/wiki/Cytotoxicity" title="Cytotoxicity">cytotoxicity</a> as various enzymes including <a href="/wiki/Hyaluronidase" title="Hyaluronidase">hyaluronidases</a>, <a href="/wiki/Collagenase" title="Collagenase">collagenases</a>, <a href="/wiki/Proteinase" class="mw-redirect" title="Proteinase">proteinases</a> and <a href="/wiki/Phospholipase" title="Phospholipase">phospholipases</a> lead to breakdown (dermonecrosis) and injury of local tissue and inflammation which leads to pain, edema and blister formation.<sup id="cite_ref-Seifert_43-0" class="reference"><a href="#cite_note-Seifert-43"><span class="cite-bracket">&#91;</span>43<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/Metalloproteinase" title="Metalloproteinase">Metalloproteinases</a> further lead to breakdown of the extracellular matrix (releasing inflammatory mediators) and cause microvascular damage, leading to hemorrhage, skeletal muscle damage (necrosis), blistering and further dermonecrosis.<sup id="cite_ref-Seifert_43-1" class="reference"><a href="#cite_note-Seifert-43"><span class="cite-bracket">&#91;</span>43<span class="cite-bracket">&#93;</span></a></sup> The metalloproteinase release of the inflammatory mediators leads to pain, swelling, and white blood cell (<a href="/wiki/Leukocyte" class="mw-redirect" title="Leukocyte">leukocyte</a>) infiltration. The lymphatic system may be damaged by the various enzymes contained in the venom leading to edema; or the lymphatic system may also allow the venom to be carried systemically.<sup id="cite_ref-Seifert_43-2" class="reference"><a href="#cite_note-Seifert-43"><span class="cite-bracket">&#91;</span>43<span class="cite-bracket">&#93;</span></a></sup> Snake venom may cause muscle damage or <a href="/wiki/Myotoxin" title="Myotoxin">myotoxicity</a> via the enzyme <a href="/wiki/Phospholipase_A2" title="Phospholipase A2">phospholipase A2</a> which disrupts the plasma membrane of muscle cells. This damage to muscle cells may cause <a href="/wiki/Rhabdomyolysis" title="Rhabdomyolysis">rhabdomyolysis</a>, respiratory muscle compromise, or both.<sup id="cite_ref-Seifert_43-3" class="reference"><a href="#cite_note-Seifert-43"><span class="cite-bracket">&#91;</span>43<span class="cite-bracket">&#93;</span></a></sup> Other enzymes such as bradykinin potentiating peptides, natriuretic peptides, <a href="/wiki/Vascular_endothelial_growth_factor" title="Vascular endothelial growth factor">vascular endothelial growth factors</a>, <a href="/wiki/Proteases" class="mw-redirect" title="Proteases">proteases</a> can also cause <a href="/wiki/Hypotension" title="Hypotension">hypotension</a> or low blood pressure.<sup id="cite_ref-Seifert_43-4" class="reference"><a href="#cite_note-Seifert-43"><span class="cite-bracket">&#91;</span>43<span class="cite-bracket">&#93;</span></a></sup> Toxins in snake venom can also cause kidney damage (nephrotoxicity) via the same inflammatory cytokines. The toxins cause direct damage to the <a href="/wiki/Glomerulus_(kidney)" title="Glomerulus (kidney)">glomeruli</a> in the kidneys as well as causing protein deposits in <a href="/wiki/Bowman%27s_capsule" title="Bowman&#39;s capsule">Bowman's capsule</a>. Or the kidneys may be indirectly damaged by envenomation due to shock, clearance of toxic substances such as immune complexes, blood degradation products, or products of muscle breakdown (rhabdomyolysis).<sup id="cite_ref-Seifert_43-5" class="reference"><a href="#cite_note-Seifert-43"><span class="cite-bracket">&#91;</span>43<span class="cite-bracket">&#93;</span></a></sup> </p><p>In <a href="/wiki/Venom-induced_consumption_coagulopathy" title="Venom-induced consumption coagulopathy">venom-induced consumption coagulopathy</a>, toxins in snake venom promote hemorrhage via activation, consumption, and subsequent depletion of clotting factors in the blood.<sup id="cite_ref-Seifert_43-6" class="reference"><a href="#cite_note-Seifert-43"><span class="cite-bracket">&#91;</span>43<span class="cite-bracket">&#93;</span></a></sup> These clotting factors normally work as part of the <a href="/wiki/Coagulation_cascade" class="mw-redirect" title="Coagulation cascade">coagulation cascade</a> in the blood to form blood clots and prevent hemorrhage. Toxins in snake venom (especially the venom of New World pit vipers (the family <a href="/wiki/Crotalina" class="mw-redirect" title="Crotalina">crotalina</a>)) may also cause low platelets (<a href="/wiki/Thrombocytopenia" title="Thrombocytopenia">thrombocytopenia</a>) or altered platelet function also leading to bleeding.<sup id="cite_ref-Seifert_43-7" class="reference"><a href="#cite_note-Seifert-43"><span class="cite-bracket">&#91;</span>43<span class="cite-bracket">&#93;</span></a></sup> </p><p>Snake venom is known to cause neuromuscular paralysis, usually as a flaccid paralysis that is descending; starting at the facial muscles, causing <a href="/wiki/Ptosis_(eyelid)" title="Ptosis (eyelid)">ptosis</a> or drooping eyelids and <a href="/wiki/Dysarthria" title="Dysarthria">dysarthria</a> or poor articulation of speech, and descending to the respiratory muscles causing respiratory compromise.<sup id="cite_ref-Seifert_43-8" class="reference"><a href="#cite_note-Seifert-43"><span class="cite-bracket">&#91;</span>43<span class="cite-bracket">&#93;</span></a></sup> The neurotoxins can either bind to and block membrane receptors at the post-synaptic neurons or they can be taken up into the pre-synaptic neuron cells and impair neurotransmitter release.<sup id="cite_ref-Seifert_43-9" class="reference"><a href="#cite_note-Seifert-43"><span class="cite-bracket">&#91;</span>43<span class="cite-bracket">&#93;</span></a></sup> Venom toxins that are taken up intra-cellularly, into the cells of the pre-synaptic neurons are much more difficult to reverse using anti-venom as they are inaccessible to the anti-venom when they are intracellular.<sup id="cite_ref-Seifert_43-10" class="reference"><a href="#cite_note-Seifert-43"><span class="cite-bracket">&#91;</span>43<span class="cite-bracket">&#93;</span></a></sup> </p><p>The strength of venom differs markedly between species and even more so between families, as measured by <a href="/wiki/Median_lethal_dose" title="Median lethal dose">median lethal dose</a> (LD<sub>50</sub>) in mice. Subcutaneous LD<sub>50</sub> varies by over 140-fold within elapids and by more than 100-fold in vipers. The amount of venom produced also differs among species, with the <a href="/wiki/Gaboon_viper" title="Gaboon viper">Gaboon viper</a> able to potentially deliver from 450 to 600 milligrams of venom in a single bite, the most of any snake.<sup id="cite_ref-Spawls_44-0" class="reference"><a href="#cite_note-Spawls-44"><span class="cite-bracket">&#91;</span>44<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/Opisthoglyphous" class="mw-redirect" title="Opisthoglyphous">Opisthoglyphous</a> colubrids have venom ranging from life-threatening (in the case of the <a href="/wiki/Boomslang" title="Boomslang">boomslang</a>) to barely noticeable (as in <i><a href="/wiki/Tantilla" title="Tantilla">Tantilla</a></i>).<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#91;<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (May 2021)">citation needed</span></a></i>&#93;</sup> </p> <div class="mw-heading mw-heading2"><h2 id="Prevention">Prevention</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=5" title="Edit section: Prevention"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure class="mw-default-size mw-halign-right" typeof="mw:File/Thumb"><a href="/wiki/File:RodriguezParkHoustonSnakes.JPG" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/db/RodriguezParkHoustonSnakes.JPG/220px-RodriguezParkHoustonSnakes.JPG" decoding="async" width="220" height="293" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/db/RodriguezParkHoustonSnakes.JPG/330px-RodriguezParkHoustonSnakes.JPG 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/db/RodriguezParkHoustonSnakes.JPG/440px-RodriguezParkHoustonSnakes.JPG 2x" data-file-width="1704" data-file-height="2272" /></a><figcaption>Sign at Sylvan Rodriguez Park in <a href="/wiki/Houston,_Texas" class="mw-redirect" title="Houston, Texas">Houston, Texas</a>, warning of the presence of snakes</figcaption></figure> <p>Snakes are most likely to bite when they feel threatened, are startled, are provoked, or when they have been cornered. Snakes are likely to approach residential areas when attracted by prey, such as <a href="/wiki/Rodents" class="mw-redirect" title="Rodents">rodents</a>. Regular <a href="/wiki/Pest_control" title="Pest control">pest control</a> can reduce the threat of snakes considerably. It is beneficial to know the species of snake that are common in local areas, or while travelling or hiking. <a href="/wiki/Africa" title="Africa">Africa</a>, <a href="/wiki/Australia" title="Australia">Australia</a>, the <a href="/wiki/Neotropics" class="mw-redirect" title="Neotropics">Neotropics</a>, and <a href="/wiki/South_Asia" title="South Asia">South Asia</a> in particular are populated by many dangerous species of snake. Being aware of—and ultimately avoiding—areas known to be heavily populated by dangerous snakes is strongly recommended.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#91;<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (July 2020)">citation needed</span></a></i>&#93;</sup> </p><p>When in the wilderness, treading heavily creates ground vibrations and noise, which will often cause snakes to flee from the area. However, this generally only applies to vipers, as some larger and more aggressive snakes in other parts of the world, such as <a href="/wiki/Mamba" title="Mamba">mambas</a> and <a href="/wiki/Cobra" title="Cobra">cobras</a>,<sup id="cite_ref-Haji_45-0" class="reference"><a href="#cite_note-Haji-45"><span class="cite-bracket">&#91;</span>45<span class="cite-bracket">&#93;</span></a></sup> will respond more aggressively. If presented with a direct encounter, it is best to remain silent and motionless. If the snake has not yet fled, it is important to step away slowly and cautiously.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#91;<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (May 2021)">citation needed</span></a></i>&#93;</sup> </p><p>The use of a flashlight when engaged in camping activities, such as gathering firewood at night, can be helpful. Snakes may also be unusually active during especially warm nights when ambient temperatures exceed 21&#160;°C (70&#160;°F). It is advised not to reach blindly into hollow logs, flip over large rocks, and enter old <a href="/wiki/Log_cabin" title="Log cabin">cabins</a> or other potential snake hiding places. When <a href="/wiki/Climbing" title="Climbing">rock climbing</a>, it is not safe to grab ledges or crevices without examining them first, as snakes are <a href="/wiki/Ectotherm" title="Ectotherm">cold-blooded</a> and often sunbathe atop rock ledges.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#91;<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (May 2021)">citation needed</span></a></i>&#93;</sup> </p><p>In the United States, more than 40 percent of people bitten by snakes intentionally put themselves in harm's way by attempting to capture wild snakes or by carelessly handling their dangerous pets—40 percent of that number had a <a href="/wiki/Blood_alcohol_level" class="mw-redirect" title="Blood alcohol level">blood alcohol level</a> of 0.1 percent or more.<sup id="cite_ref-46" class="reference"><a href="#cite_note-46"><span class="cite-bracket">&#91;</span>46<span class="cite-bracket">&#93;</span></a></sup> </p><p>It is also important to avoid snakes that <a href="/wiki/Apparent_death" title="Apparent death">appear to be dead</a>, as some species will roll over on their backs and stick out their tongue to fool potential threats. A snake's detached head can immediately act by <a href="/wiki/Reflex_action" class="mw-redirect" title="Reflex action">reflex</a> and potentially bite. The induced bite can be just as severe as that of a live snake.<sup id="cite_ref-Gold2002_2-17" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-47" class="reference"><a href="#cite_note-47"><span class="cite-bracket">&#91;</span>47<span class="cite-bracket">&#93;</span></a></sup> As a dead snake is incapable of regulating the venom injected, a bite from a dead snake can often contain large amounts of venom.<sup id="cite_ref-Suchard1999_48-0" class="reference"><a href="#cite_note-Suchard1999-48"><span class="cite-bracket">&#91;</span>48<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Treatment">Treatment</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=6" title="Edit section: Treatment"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>It may be difficult to determine if a bite by any species of snake is life-threatening. A bite by a North American <a href="/wiki/Agkistrodon_contortrix" class="mw-redirect" title="Agkistrodon contortrix">copperhead</a> on the ankle is usually a moderate injury to a healthy adult, but a bite to a child's abdomen or face by the same snake may be fatal. The outcome of all snakebites depends on a multitude of factors: the type of snake, the size, physical condition, and temperature of the snake, the age and physical condition of the person, the area and tissue bitten (e.g., foot, torso, vein or muscle), the amount of venom injected, the time it takes for the person to find treatment, and finally the quality of that treatment.<sup id="cite_ref-Gold2002_2-18" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Gold1994_49-0" class="reference"><a href="#cite_note-Gold1994-49"><span class="cite-bracket">&#91;</span>49<span class="cite-bracket">&#93;</span></a></sup> An overview of systematic reviews on different aspects of snakebite management found that the evidence base from majority of treatment modalities is low quality.<sup id="cite_ref-Interventions_for_the_management_of_50-0" class="reference"><a href="#cite_note-Interventions_for_the_management_of-50"><span class="cite-bracket">&#91;</span>50<span class="cite-bracket">&#93;</span></a></sup> An analysis of World Health Organization guidelines found that they are of low quality, with inadequate stakeholder involvement and poor methodological rigour.<sup id="cite_ref-51" class="reference"><a href="#cite_note-51"><span class="cite-bracket">&#91;</span>51<span class="cite-bracket">&#93;</span></a></sup> In addition, access to effective treatment modalities is a major challenge in some regions, particularly in most African countries.<sup id="cite_ref-:0_52-0" class="reference"><a href="#cite_note-:0-52"><span class="cite-bracket">&#91;</span>52<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Snake_identification">Snake identification</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=7" title="Edit section: Snake identification"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Identification of the snake is important in planning treatment in certain areas of the world but is not always possible. Ideally, the dead snake would be brought in with the person, but in areas where snake bite is more common, local knowledge may be sufficient to recognize the snake. However, in regions where polyvalent <a href="/wiki/Antivenom" title="Antivenom">antivenoms</a> are available, such as North America, identification of snakes is not a high-priority item. Attempting to catch or kill the offending snake also puts one at risk for re-envenomation or creating a second person bitten, and generally is not recommended.<sup id="cite_ref-auto_53-0" class="reference"><a href="#cite_note-auto-53"><span class="cite-bracket">&#91;</span>53<span class="cite-bracket">&#93;</span></a></sup> </p><p>The three types of venomous snakes that cause the majority of major clinical problems are <a href="/wiki/Viper_(animal)" class="mw-redirect" title="Viper (animal)">vipers</a>, <a href="/wiki/Bungarus" title="Bungarus">kraits</a>, and <a href="/wiki/Naja" title="Naja">cobras</a>. Knowledge of what species are present locally can be crucial, as is knowledge of typical signs and symptoms of envenomation by each type of snake. A scoring system can be used to try to determine the biting snake based on clinical features,<sup id="cite_ref-54" class="reference"><a href="#cite_note-54"><span class="cite-bracket">&#91;</span>54<span class="cite-bracket">&#93;</span></a></sup> but these scoring systems are extremely specific to particular geographical areas and might be compromised by the presence of escaped or released non-native species.<sup id="cite_ref-auto_53-1" class="reference"><a href="#cite_note-auto-53"><span class="cite-bracket">&#91;</span>53<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="First_aid">First aid</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=8" title="Edit section: First aid"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Snakebite <a href="/wiki/First_aid" title="First aid">first aid</a> recommendations vary, in part because different snakes have different types of venom. Some have little local effect, but life-threatening systemic effects, in which case containing the venom in the region of the bite by pressure immobilization is desirable. Other venoms instigate localized tissue damage around the bitten area, and immobilization may increase the severity of the damage in this area, but also reduce the total area affected; whether this trade-off is desirable remains a point of controversy. Because snakes vary from one country to another, first aid methods also vary.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#91;<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (March 2023)">citation needed</span></a></i>&#93;</sup> </p><p>Many organizations, including the <a href="/wiki/American_Medical_Association" title="American Medical Association">American Medical Association</a> and <a href="/wiki/American_Red_Cross" title="American Red Cross">American Red Cross</a>, recommend washing the bite with soap and water. Australian recommendations for snake bite treatment are against cleaning the wound. Traces of venom left on the skin/bandages from the strike can be used in combination with a snake bite identification kit to identify the species of snake. This speeds the determination of which antivenom to administer in the emergency room.<sup id="cite_ref-55" class="reference"><a href="#cite_note-55"><span class="cite-bracket">&#91;</span>55<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Pressure_immobilization">Pressure immobilization</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=9" title="Edit section: Pressure immobilization"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951" /><div role="note" class="hatnote navigation-not-searchable">Further information: <a href="/wiki/Pressure_immobilization_technique" class="mw-redirect" title="Pressure immobilization technique">Pressure immobilization technique</a></div> <figure class="mw-default-size mw-halign-right" typeof="mw:File/Thumb"><a href="/wiki/File:Bundesarchiv_Bild_135-KA-01-019,_Tibetexpedition,_Melken_einer_Schlange.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/9/95/Bundesarchiv_Bild_135-KA-01-019%2C_Tibetexpedition%2C_Melken_einer_Schlange.jpg/220px-Bundesarchiv_Bild_135-KA-01-019%2C_Tibetexpedition%2C_Melken_einer_Schlange.jpg" decoding="async" width="220" height="302" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/95/Bundesarchiv_Bild_135-KA-01-019%2C_Tibetexpedition%2C_Melken_einer_Schlange.jpg/330px-Bundesarchiv_Bild_135-KA-01-019%2C_Tibetexpedition%2C_Melken_einer_Schlange.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/95/Bundesarchiv_Bild_135-KA-01-019%2C_Tibetexpedition%2C_Melken_einer_Schlange.jpg/440px-Bundesarchiv_Bild_135-KA-01-019%2C_Tibetexpedition%2C_Melken_einer_Schlange.jpg 2x" data-file-width="582" data-file-height="800" /></a><figcaption>A <a href="/wiki/Russell%27s_viper" title="Russell&#39;s viper">Russell's viper</a> is being "milked". Laboratories use extracted snake venom to produce <a href="/wiki/Antivenom" title="Antivenom">antivenom</a>, which is often the only effective treatment for potentially fatal snakebites.</figcaption></figure> <p>As of 2008, clinical evidence for <a href="/wiki/Pressure_immobilization" class="mw-redirect" title="Pressure immobilization">pressure immobilization</a> via the use of an <a href="/wiki/Elastic_bandage" title="Elastic bandage">elastic bandage</a> is limited.<sup id="cite_ref-Currie2008_56-0" class="reference"><a href="#cite_note-Currie2008-56"><span class="cite-bracket">&#91;</span>56<span class="cite-bracket">&#93;</span></a></sup> It is recommended for snakebites that have occurred in Australia (due to <a href="/wiki/Elapids" class="mw-redirect" title="Elapids">elapids</a> which are neurotoxic).<sup id="cite_ref-Walker2013_57-0" class="reference"><a href="#cite_note-Walker2013-57"><span class="cite-bracket">&#91;</span>57<span class="cite-bracket">&#93;</span></a></sup> It is not recommended for bites from non-neurotoxic snakes such as those found in North America and other regions of the world.<sup id="cite_ref-Walker2013_57-1" class="reference"><a href="#cite_note-Walker2013-57"><span class="cite-bracket">&#91;</span>57<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-ACM2011_58-0" class="reference"><a href="#cite_note-ACM2011-58"><span class="cite-bracket">&#91;</span>58<span class="cite-bracket">&#93;</span></a></sup> The British military recommends pressure immobilization in all cases where the type of snake is unknown.<sup id="cite_ref-59" class="reference"><a href="#cite_note-59"><span class="cite-bracket">&#91;</span>59<span class="cite-bracket">&#93;</span></a></sup> </p><p>The object of pressure immobilization is to contain venom within a bitten limb and prevent it from moving through the <a href="/wiki/Lymphatic_system" title="Lymphatic system">lymphatic system</a> to the vital organs. This therapy has two components: pressure to prevent lymphatic drainage, and immobilization of the bitten limb to prevent the pumping action of the <a href="/wiki/Skeletal_muscle" title="Skeletal muscle">skeletal muscles</a>.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#91;<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (March 2023)">citation needed</span></a></i>&#93;</sup> </p> <div class="mw-heading mw-heading3"><h3 id="Antivenom">Antivenom</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=10" title="Edit section: Antivenom"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Until the advent of <a href="/wiki/Antivenom" title="Antivenom">antivenom</a>, bites from some species of snake were almost universally fatal.<sup id="cite_ref-INCHEM_60-0" class="reference"><a href="#cite_note-INCHEM-60"><span class="cite-bracket">&#91;</span>60<span class="cite-bracket">&#93;</span></a></sup> Despite huge advances in emergency therapy, antivenom is often still the only effective treatment for envenomation. The first antivenom was developed in 1895 by French physician <a href="/wiki/Albert_Calmette" title="Albert Calmette">Albert Calmette</a> for the treatment of <a href="/wiki/Indian_cobra" title="Indian cobra">Indian cobra</a> bites. Antivenom is made by injecting a small amount of venom into an animal (usually a horse or sheep) to initiate an immune system response. The resulting <a href="/wiki/Antibodies" class="mw-redirect" title="Antibodies">antibodies</a> are then harvested from the animal's blood.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#91;<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (March 2023)">citation needed</span></a></i>&#93;</sup> </p><p>Antivenom is injected into the person <a href="/wiki/Intravenous_therapy" title="Intravenous therapy">intravenously</a>, and works by binding to and neutralizing venom enzymes. It cannot undo the damage already caused by venom, so antivenom treatment should be sought as soon as possible. Modern antivenoms are usually polyvalent, making them effective against the venom of numerous snake species. Pharmaceutical companies that produce antivenom target their products against the species native to a particular area. The availability of antivenom is a major concern in some areas, including most of Africa, due to economic reasons (antivenom crisis).<sup id="cite_ref-:0_52-1" class="reference"><a href="#cite_note-:0-52"><span class="cite-bracket">&#91;</span>52<span class="cite-bracket">&#93;</span></a></sup> In Sub-Saharan Africa, the efficacy of antivenom is often poorly characterised and some of the few available products have even been found to lack effectiveness.<sup id="cite_ref-61" class="reference"><a href="#cite_note-61"><span class="cite-bracket">&#91;</span>61<span class="cite-bracket">&#93;</span></a></sup> </p><p>Although some people may develop serious adverse reactions to antivenom, such as <a href="/wiki/Anaphylaxis" title="Anaphylaxis">anaphylaxis</a>, in emergency situations this is usually treatable in a hospital setting and hence the benefit outweighs the potential consequences of not using antivenom. Giving <a href="/wiki/Adrenaline" title="Adrenaline">adrenaline</a> (epinephrine) to prevent adverse reactions to antivenom before they occur might be reasonable in cases where they occur commonly.<sup id="cite_ref-Nuch2000_62-0" class="reference"><a href="#cite_note-Nuch2000-62"><span class="cite-bracket">&#91;</span>62<span class="cite-bracket">&#93;</span></a></sup> Antihistamines do not appear to provide any benefit in preventing adverse reactions.<sup id="cite_ref-Nuch2000_62-1" class="reference"><a href="#cite_note-Nuch2000-62"><span class="cite-bracket">&#91;</span>62<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Chronic_Complications">Chronic Complications</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=11" title="Edit section: Chronic Complications"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Chronic health effects of snakebite include but are not limited to non-healing and chronic ulcers, musculoskeletal disorders, amputations, chronic kidney disease, and other neurological and endocrine complications.<sup id="cite_ref-63" class="reference"><a href="#cite_note-63"><span class="cite-bracket">&#91;</span>63<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-64" class="reference"><a href="#cite_note-64"><span class="cite-bracket">&#91;</span>64<span class="cite-bracket">&#93;</span></a></sup> The treatment of chronic complications of snakebite has not been well researched and there a systems approach consisting of a multi-component intervention.<sup id="cite_ref-65" class="reference"><a href="#cite_note-65"><span class="cite-bracket">&#91;</span>65<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Interventions_for_the_management_of_50-1" class="reference"><a href="#cite_note-Interventions_for_the_management_of-50"><span class="cite-bracket">&#91;</span>50<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Outmoded">Outmoded</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=12" title="Edit section: Outmoded"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure class="mw-default-size mw-halign-right" typeof="mw:File/Thumb"><a href="/wiki/File:Snakebite_kit.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/5/50/Snakebite_kit.jpg/220px-Snakebite_kit.jpg" decoding="async" width="220" height="130" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/50/Snakebite_kit.jpg/330px-Snakebite_kit.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/50/Snakebite_kit.jpg/440px-Snakebite_kit.jpg 2x" data-file-width="600" data-file-height="355" /></a><figcaption>Old-style snake bite kit that should not be used</figcaption></figure> <p>The following treatments, while once recommended, are considered of no use or harmful, including tourniquets, incisions, suction, application of cold, and application of electricity.<sup id="cite_ref-ACM2011_58-1" class="reference"><a href="#cite_note-ACM2011-58"><span class="cite-bracket">&#91;</span>58<span class="cite-bracket">&#93;</span></a></sup> Cases in which these treatments appear to work may be the result of <a href="/wiki/Dry_bite" title="Dry bite">dry bites</a>. </p> <ul><li>Application of a <a href="/wiki/Tourniquet" title="Tourniquet">tourniquet</a> to the bitten limb is generally not recommended. There is no convincing evidence that it is an effective first-aid tool as ordinarily applied.<sup id="cite_ref-theak_66-0" class="reference"><a href="#cite_note-theak-66"><span class="cite-bracket">&#91;</span>66<span class="cite-bracket">&#93;</span></a></sup> Tourniquets have been found to be completely ineffective in the treatment of <i><a href="/wiki/Crotalus_durissus" title="Crotalus durissus">Crotalus durissus</a></i> bites,<sup id="cite_ref-67" class="reference"><a href="#cite_note-67"><span class="cite-bracket">&#91;</span>67<span class="cite-bracket">&#93;</span></a></sup> but some positive results have been seen with properly applied tourniquets for cobra venom in the <a href="/wiki/Philippines" title="Philippines">Philippines</a>.<sup id="cite_ref-68" class="reference"><a href="#cite_note-68"><span class="cite-bracket">&#91;</span>68<span class="cite-bracket">&#93;</span></a></sup> Uninformed tourniquet use is dangerous since reducing or cutting off circulation can lead to <a href="/wiki/Gangrene" title="Gangrene">gangrene</a>, which can be fatal.<sup id="cite_ref-theak_66-1" class="reference"><a href="#cite_note-theak-66"><span class="cite-bracket">&#91;</span>66<span class="cite-bracket">&#93;</span></a></sup> The use of a compression bandage is generally as effective, and much safer.</li> <li>Cutting open the bitten area, an action often taken before suction, is not recommended since it causes further damage and increases the risk of infection; the subsequent cauterization of the area with fire or silver nitrate (also known as <i>infernal stone</i>) is also potentially threatening.<sup id="cite_ref-peola_69-0" class="reference"><a href="#cite_note-peola-69"><span class="cite-bracket">&#91;</span>69<span class="cite-bracket">&#93;</span></a></sup></li> <li>Sucking out venom, either by mouth or with a pump, does not work and may harm the affected area directly.<sup id="cite_ref-pmid16781926_70-0" class="reference"><a href="#cite_note-pmid16781926-70"><span class="cite-bracket">&#91;</span>70<span class="cite-bracket">&#93;</span></a></sup> Suction started after three minutes removes a clinically insignificant quantity—less than one-thousandth of the venom injected—as shown in a human study.<sup id="cite_ref-71" class="reference"><a href="#cite_note-71"><span class="cite-bracket">&#91;</span>71<span class="cite-bracket">&#93;</span></a></sup> In a study with pigs, suction not only caused no improvement but led to <a href="/wiki/Necrosis" title="Necrosis">necrosis</a> in the suctioned area.<sup id="cite_ref-pmid11055564_72-0" class="reference"><a href="#cite_note-pmid11055564-72"><span class="cite-bracket">&#91;</span>72<span class="cite-bracket">&#93;</span></a></sup> Suctioning by mouth presents a risk of further poisoning through the mouth's <a href="/wiki/Oral_mucosa" title="Oral mucosa">mucous tissues</a>.<sup id="cite_ref-73" class="reference"><a href="#cite_note-73"><span class="cite-bracket">&#91;</span>73<span class="cite-bracket">&#93;</span></a></sup> The helper may also release bacteria into the person's wound, leading to infection.</li> <li>Immersion in warm water or sour milk, followed by the application of <a href="/wiki/Snake-stones" class="mw-redirect" title="Snake-stones">snake-stones</a> (also known as <i>la Pierre Noire</i>), which are believed to draw off the poison in much the way a sponge soaks up water.</li> <li>Application of a one-percent solution of <a href="/wiki/Potassium_permanganate" title="Potassium permanganate">potassium permanganate</a> or <a href="/wiki/Chromic_acid" title="Chromic acid">chromic acid</a> to the cut, exposed area.<sup id="cite_ref-peola_69-1" class="reference"><a href="#cite_note-peola-69"><span class="cite-bracket">&#91;</span>69<span class="cite-bracket">&#93;</span></a></sup> The latter substance is notably toxic and carcinogenic.</li> <li>Drinking abundant quantities of alcohol following the cauterization or disinfection of the wound area.<sup id="cite_ref-peola_69-2" class="reference"><a href="#cite_note-peola-69"><span class="cite-bracket">&#91;</span>69<span class="cite-bracket">&#93;</span></a></sup></li> <li>Use of electroshock therapy in animal tests has shown this treatment to be useless and potentially dangerous.<sup id="cite_ref-74" class="reference"><a href="#cite_note-74"><span class="cite-bracket">&#91;</span>74<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-75" class="reference"><a href="#cite_note-75"><span class="cite-bracket">&#91;</span>75<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-76" class="reference"><a href="#cite_note-76"><span class="cite-bracket">&#91;</span>76<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-77" class="reference"><a href="#cite_note-77"><span class="cite-bracket">&#91;</span>77<span class="cite-bracket">&#93;</span></a></sup></li></ul> <p>In extreme cases, in remote areas, all of these misguided attempts at treatment have resulted in injuries far worse than an otherwise mild to moderate snakebite. In worst-case scenarios, thoroughly constricting tourniquets have been applied to bitten limbs, completely shutting off blood flow to the area. By the time the person finally reached appropriate medical facilities, their limbs had to be <a href="/wiki/Amputated" class="mw-redirect" title="Amputated">amputated</a>.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#91;<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (March 2023)">citation needed</span></a></i>&#93;</sup> </p> <div class="mw-heading mw-heading3"><h3 id="In_development">In development</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=13" title="Edit section: In development"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Several new drugs and treatments are under development for snakebite. For instance, the metal chelator <a href="/wiki/Dimercaprol" title="Dimercaprol">dimercaprol</a> has recently been shown to potently antagonize the activity of Zn<sup>2+</sup>-dependent snake venom <a href="/wiki/Metalloproteinase" title="Metalloproteinase">metalloproteinases</a> <i>in vitro</i>.<sup id="cite_ref-78" class="reference"><a href="#cite_note-78"><span class="cite-bracket">&#91;</span>78<span class="cite-bracket">&#93;</span></a></sup> New <a href="/wiki/Monoclonal_antibody" title="Monoclonal antibody">monoclonal antibodies</a>, polymer gels and a small molecule inhibitor called <a href="/wiki/Varespladib" title="Varespladib">Varespladib</a> are in development.<sup id="cite_ref-79" class="reference"><a href="#cite_note-79"><span class="cite-bracket">&#91;</span>79<span class="cite-bracket">&#93;</span></a></sup> A core outcome set (minimal list of consensus outcomes that should be used in future intervention research) for snakebite in South Asia is being developed.<sup id="cite_ref-80" class="reference"><a href="#cite_note-80"><span class="cite-bracket">&#91;</span>80<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Epidemiology">Epidemiology</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=14" title="Edit section: Epidemiology"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951" /><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Epidemiology_of_snakebites" title="Epidemiology of snakebites">Epidemiology of snakebites</a></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951" /><div role="note" class="hatnote navigation-not-searchable">See also: <a href="/wiki/List_of_fatal_snake_bites_in_the_United_States" title="List of fatal snake bites in the United States">List of fatal snake bites in the United States</a> and <a href="/wiki/List_of_fatal_snake_bites_in_Australia" title="List of fatal snake bites in Australia">List of fatal snake bites in Australia</a></div> <style data-mw-deduplicate="TemplateStyles:r1273380762/mw-parser-output/.tmulti">.mw-parser-output .tmulti .multiimageinner{display:flex;flex-direction:column}.mw-parser-output .tmulti .trow{display:flex;flex-direction:row;clear:left;flex-wrap:wrap;width:100%;box-sizing:border-box}.mw-parser-output .tmulti .tsingle{margin:1px;float:left}.mw-parser-output .tmulti .theader{clear:both;font-weight:bold;text-align:center;align-self:center;background-color:transparent;width:100%}.mw-parser-output .tmulti .thumbcaption{background-color:transparent}.mw-parser-output .tmulti .text-align-left{text-align:left}.mw-parser-output .tmulti .text-align-right{text-align:right}.mw-parser-output .tmulti .text-align-center{text-align:center}@media all and (max-width:720px){.mw-parser-output .tmulti .thumbinner{width:100%!important;box-sizing:border-box;max-width:none!important;align-items:center}.mw-parser-output .tmulti .trow{justify-content:center}.mw-parser-output .tmulti .tsingle{float:none!important;max-width:100%!important;box-sizing:border-box;text-align:center}.mw-parser-output .tmulti .tsingle .thumbcaption{text-align:left}.mw-parser-output .tmulti .trow>.thumbcaption{text-align:center}}@media screen{html.skin-theme-clientpref-night .mw-parser-output .tmulti .multiimageinner span:not(.skin-invert-image):not(.skin-invert):not(.bg-transparent) img{background-color:white}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .tmulti .multiimageinner span:not(.skin-invert-image):not(.skin-invert):not(.bg-transparent) img{background-color:white}}</style><div class="thumb tmulti tright"><div class="thumbinner multiimageinner" style="width:354px;max-width:354px"><div class="trow"><div class="tsingle" style="width:352px;max-width:352px"><div class="thumbimage"><span typeof="mw:File"><a href="/wiki/File:World_distribution_of_snakes.svg" class="mw-file-description"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d4/World_distribution_of_snakes.svg/350px-World_distribution_of_snakes.svg.png" decoding="async" width="350" height="178" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d4/World_distribution_of_snakes.svg/525px-World_distribution_of_snakes.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d4/World_distribution_of_snakes.svg/700px-World_distribution_of_snakes.svg.png 2x" data-file-width="940" data-file-height="477" /></a></span></div><div class="thumbcaption">Map showing the approximate world distribution of snakes</div></div></div><div class="trow"><div class="tsingle" style="width:352px;max-width:352px"><div class="thumbimage"><span typeof="mw:File"><a href="/wiki/File:Number_of_snake_envenomings_(2007).svg" class="mw-file-description"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ee/Number_of_snake_envenomings_%282007%29.svg/500px-Number_of_snake_envenomings_%282007%29.svg.png" decoding="async" width="350" height="178" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ee/Number_of_snake_envenomings_%282007%29.svg/525px-Number_of_snake_envenomings_%282007%29.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/ee/Number_of_snake_envenomings_%282007%29.svg/700px-Number_of_snake_envenomings_%282007%29.svg.png 2x" data-file-width="940" data-file-height="477" /></a></span></div><div class="thumbcaption">Map showing the global distribution of snakebite morbidity</div></div></div></div></div> <p>Earlier estimates for snakebite vary from 1.2 to 5.5&#160;million, with 421,000 to 2.5&#160;million being envenomings, and causing 20,000 to 125,000 deaths.<sup id="cite_ref-WHO2015_3-16" class="reference"><a href="#cite_note-WHO2015-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Kast2008_14-5" class="reference"><a href="#cite_note-Kast2008-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup> More recent modelling estimates that in 2019, about 63,400 people died globally from snakebite, with 51,100 of these deaths happening in India.<sup id="cite_ref-81" class="reference"><a href="#cite_note-81"><span class="cite-bracket">&#91;</span>81<span class="cite-bracket">&#93;</span></a></sup> Since reporting is not mandatory in much of the world, the data on the frequency of snakebites is not precise.<sup id="cite_ref-Kast2008_14-6" class="reference"><a href="#cite_note-Kast2008-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup> Many people who survive bites have permanent tissue damage caused by venom, leading to disability.<sup id="cite_ref-Gutierrez2007_18-9" class="reference"><a href="#cite_note-Gutierrez2007-18"><span class="cite-bracket">&#91;</span>18<span class="cite-bracket">&#93;</span></a></sup> Most snake envenomings and fatalities occur in <a href="/wiki/South_Asia" title="South Asia">South Asia</a>, <a href="/wiki/Southeast_Asia" title="Southeast Asia">Southeast Asia</a>, and <a href="/wiki/Sub-Saharan_Africa" title="Sub-Saharan Africa">sub-Saharan Africa</a>, with <a href="/wiki/India" title="India">India</a> reporting the most snakebite deaths of any country.<sup id="cite_ref-Kast2008_14-7" class="reference"><a href="#cite_note-Kast2008-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup> Available evidence on the effect of climate change on the epidemiology of snakebite is limited but it is expected that there will be a geographic shift in the risk of snakebite: northwards in North America and southwards in South America and Mozambique, and increase in the incidence of bite in Sri Lanka.<sup id="cite_ref-82" class="reference"><a href="#cite_note-82"><span class="cite-bracket">&#91;</span>82<span class="cite-bracket">&#93;</span></a></sup> </p><p>Most snakebites are caused by non-venomous snakes. Of the roughly 3,000 known species of snake found worldwide, only 15% are considered dangerous to humans.<sup id="cite_ref-Gold2002_2-19" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Kast2008_14-8" class="reference"><a href="#cite_note-Kast2008-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup> Snakes are found on every continent except <a href="/wiki/Antarctica" title="Antarctica">Antarctica</a>.<sup id="cite_ref-Kast2008_14-9" class="reference"><a href="#cite_note-Kast2008-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup> The most diverse and widely distributed snake family, the <a href="/wiki/Colubrid" class="mw-redirect" title="Colubrid">colubrids</a>, has approximately 700 venomous species,<sup id="cite_ref-Mackessy2002_83-0" class="reference"><a href="#cite_note-Mackessy2002-83"><span class="cite-bracket">&#91;</span>83<span class="cite-bracket">&#93;</span></a></sup> but only five <a href="/wiki/Genera" class="mw-redirect" title="Genera">genera</a>—<a href="/wiki/Boomslang" title="Boomslang">boomslangs</a>, <a href="/wiki/Thelotornis" class="mw-redirect" title="Thelotornis">twig snakes</a>, <a href="/wiki/Rhabdophis" title="Rhabdophis">keelback snakes</a>, <a href="/wiki/Philodryas" title="Philodryas">green snakes</a>, and <a href="/wiki/Tachymenis" title="Tachymenis">slender snakes</a>—have caused human fatalities.<sup id="cite_ref-Mackessy2002_83-1" class="reference"><a href="#cite_note-Mackessy2002-83"><span class="cite-bracket">&#91;</span>83<span class="cite-bracket">&#93;</span></a></sup> </p><p>Worldwide, snakebites occur most frequently in the summer season when snakes are active and humans are outdoors.<sup id="cite_ref-Kast2008_14-10" class="reference"><a href="#cite_note-Kast2008-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-WingertChan1988_84-0" class="reference"><a href="#cite_note-WingertChan1988-84"><span class="cite-bracket">&#91;</span>84<span class="cite-bracket">&#93;</span></a></sup> Agricultural and tropical regions report more snakebites than anywhere else.<sup id="cite_ref-Kast2008_14-11" class="reference"><a href="#cite_note-Kast2008-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Gutierrez2006_28-1" class="reference"><a href="#cite_note-Gutierrez2006-28"><span class="cite-bracket">&#91;</span>28<span class="cite-bracket">&#93;</span></a></sup> In the United States, those bitten are typically male and between 17 and 27 years of age.<sup id="cite_ref-Gold2002_2-20" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-WingertChan1988_84-1" class="reference"><a href="#cite_note-WingertChan1988-84"><span class="cite-bracket">&#91;</span>84<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-85" class="reference"><a href="#cite_note-85"><span class="cite-bracket">&#91;</span>85<span class="cite-bracket">&#93;</span></a></sup> Children and the elderly are the most likely to die.<sup id="cite_ref-Gold2002_2-21" class="reference"><a href="#cite_note-Gold2002-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Gold1994_49-1" class="reference"><a href="#cite_note-Gold1994-49"><span class="cite-bracket">&#91;</span>49<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Mechanics">Mechanics</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=15" title="Edit section: Mechanics"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951" /><div role="note" class="hatnote navigation-not-searchable">See also: <a href="/wiki/Envenomation" title="Envenomation">Envenomation</a></div> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/File:Snake_Venom_Delivery_System_Diagram.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Snake_Venom_Delivery_System_Diagram.jpg/220px-Snake_Venom_Delivery_System_Diagram.jpg" decoding="async" width="220" height="220" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Snake_Venom_Delivery_System_Diagram.jpg/330px-Snake_Venom_Delivery_System_Diagram.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Snake_Venom_Delivery_System_Diagram.jpg/440px-Snake_Venom_Delivery_System_Diagram.jpg 2x" data-file-width="600" data-file-height="600" /></a><figcaption>Basic diagram of a snake's venom delivery system</figcaption></figure> <p>When venomous snakes bite a target, they secrete <a href="/wiki/Venom" title="Venom">venom</a> through their venom delivery system. The venom delivery system generally consists of two venom glands, a compressor muscle, venom ducts, a fang sheath, and <a href="/wiki/Fang" title="Fang">fangs</a>. The primary and accessory venom glands store the venom quantities required during <a href="/wiki/Envenomation" title="Envenomation">envenomation</a>. The compressor muscle contracts during bites to increase the pressure throughout the venom delivery system. The pressurized venom travels through the primary venom duct to the secondary venom duct that leads down through the fang sheath and fang. The venom is then expelled through the exit <a href="/wiki/Body_orifice" title="Body orifice">orifice</a> of the fang. The total volume and flow rate of venom administered into a target varies widely, sometimes as much as an order of magnitude. One of the largest factors is snake species and size, larger snakes have been shown to administer larger quantities of venom.<sup id="cite_ref-Hayes_et_al._2002_86-0" class="reference"><a href="#cite_note-Hayes_et_al._2002-86"><span class="cite-bracket">&#91;</span>86<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Predatory_vs._defensive_bites">Predatory vs. defensive bites</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=16" title="Edit section: Predatory vs. defensive bites"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Snake bites are classified as either predatory or defensive. During defensive strikes, the rate of venom expulsion and total volume of venom expelled is much greater than during predatory strikes. Defensive strikes can have 10 times as much venom volume expelled at 8.5 times the flow rate.<sup id="cite_ref-87" class="reference"><a href="#cite_note-87"><span class="cite-bracket">&#91;</span>87<span class="cite-bracket">&#93;</span></a></sup> This can be explained by the snake's need to quickly subdue a threat. While employing similar venom expulsion mechanics, predatory strikes are quite different from defensive strikes. Snakes usually release the prey shortly after the envenomation allowing the prey to run away and die. Releasing prey prevents retaliatory damage to the snake. The venom scent allows the snake to relocate the prey once it is deceased.<sup id="cite_ref-Hayes_et_al._2002_86-1" class="reference"><a href="#cite_note-Hayes_et_al._2002-86"><span class="cite-bracket">&#91;</span>86<span class="cite-bracket">&#93;</span></a></sup> The amount of venom injected has been shown to increase with the mass of the prey animal.<sup id="cite_ref-88" class="reference"><a href="#cite_note-88"><span class="cite-bracket">&#91;</span>88<span class="cite-bracket">&#93;</span></a></sup> Larger venom volumes allow snakes to effectively euthanize larger prey while remaining economical during strikes against smaller prey. This is an important skill as venom is a metabolically expensive resource.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#91;<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (May 2021)">citation needed</span></a></i>&#93;</sup> </p> <div class="mw-heading mw-heading3"><h3 id="Venom_Metering">Venom Metering</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=17" title="Edit section: Venom Metering"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Venom metering is the ability of a snake to have neurological control over the amount of venom released into a target during a strike based on situational cues. This ability would prove useful as venom is a limited resource, larger animals are less susceptible to the effects of venom, and various situations require different levels of force. There is a lot of evidence to support the venom metering hypothesis. For example, snakes frequently use more venom during defensive strikes, administer more venom to larger prey, and are capable of dry biting. A dry bite is a bite from a venomous snake that results in very little or no venom expulsion, leaving the target asymptomatic.<sup id="cite_ref-89" class="reference"><a href="#cite_note-89"><span class="cite-bracket">&#91;</span>89<span class="cite-bracket">&#93;</span></a></sup> However, there is debate among many academics about venom metering in snakes. The alternative to venom metering is the pressure balance hypothesis.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#91;<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (March 2023)">citation needed</span></a></i>&#93;</sup> </p><p>The pressure balance hypothesis cites the retraction of the fang sheath as the many mechanisms for producing outward venom flow from the venom delivery system. When isolated, fang sheath retraction has experimentally been shown to induce very high pressures in the venom delivery system.<sup id="cite_ref-90" class="reference"><a href="#cite_note-90"><span class="cite-bracket">&#91;</span>90<span class="cite-bracket">&#93;</span></a></sup> A similar method was used to stimulate the compressor musculature, the main muscle responsible for the contraction and squeezing of the venom gland, and then measuring the induced pressures. It was determined that the pressure created from the fang sheath retraction was at times an order of magnitude greater than those created by the compressor musculature. Snakes do not have direct neurological control of the fang sheath, it can only be retracted as the fangs enter a target and the target's skin and body provide substantial resistance to retract the sheath. For these reasons, the pressure balance hypothesis concludes that external factors, mainly the bite and physical mechanics, are responsible for the quantity of venom expelled.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#91;<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (March 2023)">citation needed</span></a></i>&#93;</sup> </p> <div class="mw-heading mw-heading3"><h3 id="Venom_Spitting">Venom Spitting</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=18" title="Edit section: Venom Spitting"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Venom spitting is another venom delivery method that is unique to some Asiatic and African <a href="/wiki/Cobra" title="Cobra">cobras</a>. In venom spitting, a stream of venom is propelled at very high pressures outwards up to 3 meters (300 centimeters). The venom stream is usually aimed at the eyes and face of the target as a deterrent for predators. There are non-spitting cobras that provide useful information on the unique mechanics behind venom spitting. Unlike the elongated oval shaped exit orifices of non-spitting cobras, spitting cobras have circular exit orifice at their fang tips.<sup id="cite_ref-91" class="reference"><a href="#cite_note-91"><span class="cite-bracket">&#91;</span>91<span class="cite-bracket">&#93;</span></a></sup> This combined with the ability to partially retract their fang sheath by displacing the palato-maxillary arch and contracting the adductor mandibulae, allows the spitting cobras to create large pressures within the venom delivery system.<sup id="cite_ref-92" class="reference"><a href="#cite_note-92"><span class="cite-bracket">&#91;</span>92<span class="cite-bracket">&#93;</span></a></sup> While venom spitting is a less common venom delivery system, the venom can still cause the effects if ingested.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#91;<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (May 2021)">citation needed</span></a></i>&#93;</sup> </p> <div class="mw-heading mw-heading2"><h2 id="Society_and_culture">Society and culture</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=19" title="Edit section: Society and culture"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951" /><div role="note" class="hatnote navigation-not-searchable">See also: <a href="/wiki/Serpent_(symbolism)" class="mw-redirect" title="Serpent (symbolism)">Serpent (symbolism)</a></div> <figure class="mw-default-size mw-halign-right" typeof="mw:File/Thumb"><a href="/wiki/File:Benczur-kleopatra.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e9/Benczur-kleopatra.jpg/220px-Benczur-kleopatra.jpg" decoding="async" width="220" height="326" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e9/Benczur-kleopatra.jpg/330px-Benczur-kleopatra.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e9/Benczur-kleopatra.jpg/440px-Benczur-kleopatra.jpg 2x" data-file-width="1081" data-file-height="1600" /></a><figcaption>According to tradition, <a href="/wiki/Cleopatra" title="Cleopatra">Cleopatra VII</a> famously committed suicide by snakebite to her left breast, as depicted in this 1911 painting by Hungarian artist <a href="/wiki/Gyula_Bencz%C3%BAr" title="Gyula Benczúr">Gyula Benczúr</a>.</figcaption></figure> <p>Snakes were both <a href="/wiki/Snake_worship" title="Snake worship">revered and worshipped</a> and <a href="/wiki/Ophidiophobia" title="Ophidiophobia">feared</a> by early civilizations. The <a href="/wiki/Ancient_Egyptians" class="mw-redirect" title="Ancient Egyptians">ancient Egyptians</a> recorded prescribed treatments for snakebites as early as the <a href="/wiki/Thirteenth_dynasty_of_Egypt" class="mw-redirect" title="Thirteenth dynasty of Egypt">Thirteenth Dynasty</a> in the <a href="/wiki/Brooklyn_Papyrus" title="Brooklyn Papyrus">Brooklyn Papyrus</a>, which includes at least seven venomous species common to the region today, such as the <a href="/wiki/Cerastes_(genus)" title="Cerastes (genus)">horned vipers</a>.<sup id="cite_ref-Schneemann2004_93-0" class="reference"><a href="#cite_note-Schneemann2004-93"><span class="cite-bracket">&#91;</span>93<span class="cite-bracket">&#93;</span></a></sup> In <a href="/wiki/Judaism" title="Judaism">Judaism</a>, the <a href="/wiki/Nehushtan" title="Nehushtan">Nehushtan</a> was a pole with a snake made of copper fixed upon it. The object was regarded as a divinely empowered instrument of God that could bring healing to Jews bitten by venomous snakes while they were wandering in the desert after their <a href="/wiki/Exodus_from_Egypt" class="mw-redirect" title="Exodus from Egypt">exodus from Egypt</a>. Healing was said to occur by merely looking at the object as it was held up by <a href="/wiki/Moses" title="Moses">Moses</a>.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">&#91;<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (March 2023)">citation needed</span></a></i>&#93;</sup> </p><p>Historically, snakebites were seen as a means of execution in some cultures.<sup id="cite_ref-94" class="reference"><a href="#cite_note-94"><span class="cite-bracket">&#91;</span>94<span class="cite-bracket">&#93;</span></a></sup> Reportedly, in <a href="/wiki/Southern_Han" title="Southern Han">Southern Han</a> during <a href="/wiki/China" title="China">China</a>'s <a href="/wiki/Five_Dynasties_and_Ten_Kingdoms_period" title="Five Dynasties and Ten Kingdoms period">Five Dynasties and Ten Kingdoms period</a> and in <a href="/wiki/India" title="India">India</a> a form of capital punishment was to throw people into <a href="/wiki/Snake_pit" title="Snake pit">snake pits</a>, leaving people to die from multiple venomous bites.<sup id="cite_ref-Anil2004_95-0" class="reference"><a href="#cite_note-Anil2004-95"><span class="cite-bracket">&#91;</span>95<span class="cite-bracket">&#93;</span></a></sup> According to popular belief, the Egyptian queen <a href="/wiki/Cleopatra" title="Cleopatra">Cleopatra VII</a> committed suicide by letting herself be bitten by an <a href="/wiki/Asp_(reptile)" class="mw-redirect" title="Asp (reptile)">asp</a>—likely an <a href="/wiki/Egyptian_cobra" title="Egyptian cobra">Egyptian cobra</a><sup id="cite_ref-Schneemann2004_93-1" class="reference"><a href="#cite_note-Schneemann2004-93"><span class="cite-bracket">&#91;</span>93<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Smithsonian_96-0" class="reference"><a href="#cite_note-Smithsonian-96"><span class="cite-bracket">&#91;</span>96<span class="cite-bracket">&#93;</span></a></sup>—after hearing of <a href="/wiki/Mark_Antony" title="Mark Antony">Mark Antony</a>'s death, while some contemporary ancient authors rather assumed a direct application of poison.<sup id="cite_ref-97" class="reference"><a href="#cite_note-97"><span class="cite-bracket">&#91;</span>97<span class="cite-bracket">&#93;</span></a></sup> </p><p>Snakebite as a surreptitious form of murder has been featured in stories such as Sir <a href="/wiki/Arthur_Conan_Doyle" title="Arthur Conan Doyle">Arthur Conan Doyle</a>'s <i><a href="/wiki/The_Adventure_of_the_Speckled_Band" title="The Adventure of the Speckled Band">The Adventure of the Speckled Band</a></i>, but actual occurrences are virtually unheard of, with only a few documented cases.<sup id="cite_ref-Anil2004_95-1" class="reference"><a href="#cite_note-Anil2004-95"><span class="cite-bracket">&#91;</span>95<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Warrell2009_98-0" class="reference"><a href="#cite_note-Warrell2009-98"><span class="cite-bracket">&#91;</span>98<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Straight1994_99-0" class="reference"><a href="#cite_note-Straight1994-99"><span class="cite-bracket">&#91;</span>99<span class="cite-bracket">&#93;</span></a></sup> It has been suggested that <a href="/wiki/Boris_III_of_Bulgaria" title="Boris III of Bulgaria">Boris III of Bulgaria</a>, who was allied to <a href="/wiki/Nazi_Germany" title="Nazi Germany">Nazi Germany</a> during <a href="/wiki/World_War_II" title="World War II">World War II</a>, may have been killed with snake venom,<sup id="cite_ref-Anil2004_95-2" class="reference"><a href="#cite_note-Anil2004-95"><span class="cite-bracket">&#91;</span>95<span class="cite-bracket">&#93;</span></a></sup> although there is no definitive evidence. At least one attempted suicide by snakebite has been documented in medical literature involving a <a href="/wiki/Bitis_arietans" class="mw-redirect" title="Bitis arietans">puff adder</a> bite to the hand.<sup id="cite_ref-Strubel2008_100-0" class="reference"><a href="#cite_note-Strubel2008-100"><span class="cite-bracket">&#91;</span>100<span class="cite-bracket">&#93;</span></a></sup> </p><p>In <a href="/wiki/Jainism" title="Jainism">Jainism</a>, the goddess <a href="/wiki/Padmavati_(Jainism)" class="mw-redirect" title="Padmavati (Jainism)">Padmāvatī</a> has been associated with curing snakebites.<sup id="cite_ref-101" class="reference"><a href="#cite_note-101"><span class="cite-bracket">&#91;</span>101<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Research">Research</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=20" title="Edit section: Research"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>In 2018, the <a href="/wiki/World_Health_Organization" title="World Health Organization">World Health Organization</a> listed snakebite envenoming as a neglected tropical disease.<sup id="cite_ref-102" class="reference"><a href="#cite_note-102"><span class="cite-bracket">&#91;</span>102<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-103" class="reference"><a href="#cite_note-103"><span class="cite-bracket">&#91;</span>103<span class="cite-bracket">&#93;</span></a></sup> In 2019, they launched a strategy to prevent and control snakebite envenoming, which involved a program targeting affected communities and their health systems.<sup id="cite_ref-104" class="reference"><a href="#cite_note-104"><span class="cite-bracket">&#91;</span>104<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-105" class="reference"><a href="#cite_note-105"><span class="cite-bracket">&#91;</span>105<span class="cite-bracket">&#93;</span></a></sup> A policy analysis however found that the placement of snakebite in the global health agenda of WHO is fragile due to reluctance to accept the disease in the neglected tropical disease community and the perceived colonial nature of the network driving the agenda.<sup id="cite_ref-106" class="reference"><a href="#cite_note-106"><span class="cite-bracket">&#91;</span>106<span class="cite-bracket">&#93;</span></a></sup> </p><p>Key institutions conducting snakebite research on snakebite are the George Institute for Global Health, the Liverpool School of Tropical Medicine, and the Indian Institute of Science. </p> <div class="mw-heading mw-heading2"><h2 id="Other_animals">Other animals</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=21" title="Edit section: Other animals"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Several animals acquired immunity against the venom of snakes that occur in the same habitat.<sup id="cite_ref-107" class="reference"><a href="#cite_note-107"><span class="cite-bracket">&#91;</span>107<span class="cite-bracket">&#93;</span></a></sup> This has been documented in some humans as well.<sup id="cite_ref-108" class="reference"><a href="#cite_note-108"><span class="cite-bracket">&#91;</span>108<span class="cite-bracket">&#93;</span></a></sup> </p> <div style="clear:both;" class=""></div> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=22" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-CDC2012-1"><span 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href="#cite_ref-CDC2012_1-15"><sup><i><b>p</b></i></sup></a></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.cdc.gov/niosh/topics/snakes/">"Venomous Snakes"</a>. <a href="/wiki/U.S._National_Institute_for_Occupational_Safety_and_Health" class="mw-redirect" title="U.S. National Institute for Occupational Safety and Health">U.S. National Institute for Occupational Safety and Health</a>. 24 February 2012. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20150429051901/http://www.cdc.gov/niosh/topics/snakes/">Archived</a> from the original on 29 April 2015<span class="reference-accessdate">. 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"Bites of venomous snakes". <i>The New England Journal of Medicine</i>. <b>347</b> (5): <span class="nowrap">347–</span>356. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1056%2FNEJMra013477">10.1056/NEJMra013477</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a>&#160;<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12151473">12151473</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=The+New+England+Journal+of+Medicine&amp;rft.atitle=Bites+of+venomous+snakes&amp;rft.volume=347&amp;rft.issue=5&amp;rft.pages=%3Cspan+class%3D%22nowrap%22%3E347-%3C%2Fspan%3E356&amp;rft.date=2002-08&amp;rft_id=info%3Adoi%2F10.1056%2FNEJMra013477&amp;rft_id=info%3Apmid%2F12151473&amp;rft.aulast=Gold&amp;rft.aufirst=BS&amp;rft.au=Dart%2C+RC&amp;rft.au=Barish%2C+RA&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-WHO2015-3"><span class="mw-cite-backlink">^ <a href="#cite_ref-WHO2015_3-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-WHO2015_3-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-WHO2015_3-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-WHO2015_3-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-WHO2015_3-4"><sup><i><b>e</b></i></sup></a> <a href="#cite_ref-WHO2015_3-5"><sup><i><b>f</b></i></sup></a> <a href="#cite_ref-WHO2015_3-6"><sup><i><b>g</b></i></sup></a> <a href="#cite_ref-WHO2015_3-7"><sup><i><b>h</b></i></sup></a> <a href="#cite_ref-WHO2015_3-8"><sup><i><b>i</b></i></sup></a> <a href="#cite_ref-WHO2015_3-9"><sup><i><b>j</b></i></sup></a> <a href="#cite_ref-WHO2015_3-10"><sup><i><b>k</b></i></sup></a> <a href="#cite_ref-WHO2015_3-11"><sup><i><b>l</b></i></sup></a> <a href="#cite_ref-WHO2015_3-12"><sup><i><b>m</b></i></sup></a> <a href="#cite_ref-WHO2015_3-13"><sup><i><b>n</b></i></sup></a> <a href="#cite_ref-WHO2015_3-14"><sup><i><b>o</b></i></sup></a> <a href="#cite_ref-WHO2015_3-15"><sup><i><b>p</b></i></sup></a> <a href="#cite_ref-WHO2015_3-16"><sup><i><b>q</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.who.int/mediacentre/factsheets/fs373/en/">"Animal bites: Fact sheet N°373"</a>. <a href="/wiki/World_Health_Organization" title="World Health Organization">World Health Organization</a>. February 2015. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20150504100257/http://www.who.int/mediacentre/factsheets/fs373/en/">Archived</a> from the original on 4 May 2015<span class="reference-accessdate">. Retrieved <span class="nowrap">19 May</span> 2015</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=unknown&amp;rft.btitle=Animal+bites%3A+Fact+sheet+N%C2%B0373&amp;rft.pub=World+Health+Organization&amp;rft.date=2015-02&amp;rft_id=https%3A%2F%2Fwww.who.int%2Fmediacentre%2Ffactsheets%2Ffs373%2Fen%2F&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.fs.usda.gov/detail/eldorado/learning/safety-ethics/?cid=STELPRDB5259659">"Eldorado - Outdoor Safety &amp; Ethics"</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=unknown&amp;rft.btitle=Eldorado+-+Outdoor+Safety+%26+Ethics&amp;rft_id=https%3A%2F%2Fwww.fs.usda.gov%2Fdetail%2Feldorado%2Flearning%2Fsafety-ethics%2F%3Fcid%3DSTELPRDB5259659&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-5">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://wildlife.utah.gov/news/utah-wildlife-news/1202-rattlesnake-encounter-what-to-do.html">"What to do if you encounter a rattlesnake"</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=unknown&amp;rft.btitle=What+to+do+if+you+encounter+a+rattlesnake&amp;rft_id=https%3A%2F%2Fwildlife.utah.gov%2Fnews%2Futah-wildlife-news%2F1202-rattlesnake-encounter-what-to-do.html&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-6">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://reptilesmagazine.com/alcohol-and-snake-bites/">"Alcohol and Snake Bites – Reptiles Magazine"</a>. December 2011.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=unknown&amp;rft.btitle=Alcohol+and+Snake+Bites+%E2%80%93+Reptiles+Magazine&amp;rft.date=2011-12&amp;rft_id=https%3A%2F%2Freptilesmagazine.com%2Falcohol-and-snake-bites%2F&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-WHONeg-7"><span class="mw-cite-backlink">^ <a href="#cite_ref-WHONeg_7-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-WHONeg_7-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-WHONeg_7-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-WHONeg_7-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-WHONeg_7-4"><sup><i><b>e</b></i></sup></a> <a href="#cite_ref-WHONeg_7-5"><sup><i><b>f</b></i></sup></a> <a href="#cite_ref-WHONeg_7-6"><sup><i><b>g</b></i></sup></a> <a href="#cite_ref-WHONeg_7-7"><sup><i><b>h</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20150930063057/http://www.who.int/neglected_diseases/diseases/snakebites/en/">"Neglected tropical diseases: Snakebite"</a>. <a href="/wiki/World_Health_Organization" title="World Health Organization">World Health Organization</a>. 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Retrieved <span class="nowrap">19 May</span> 2015</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=unknown&amp;rft.btitle=Neglected+tropical+diseases%3A+Snakebite&amp;rft.pub=World+Health+Organization&amp;rft_id=https%3A%2F%2Fwww.who.int%2Fneglected_diseases%2Fdiseases%2Fsnakebites%2Fen%2F&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-Marx2010-8"><span class="mw-cite-backlink">^ <a href="#cite_ref-Marx2010_8-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Marx2010_8-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFMarx2010" class="citation book cs1">Marx JA (2010). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=u7TNcpCeqx8C&amp;pg=PA746"><i>Rosen's emergency medicine: concepts and clinical practice</i></a> (7&#160;ed.). Philadelphia: Mosby/Elsevier. p.&#160;746. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a>&#160;<a href="/wiki/Special:BookSources/978-0-323-05472-0" title="Special:BookSources/978-0-323-05472-0"><bdi>978-0-323-05472-0</bdi></a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20150521114649/https://books.google.com/books?id=u7TNcpCeqx8C&amp;pg=PA746">Archived</a> from the original on 21 May 2015.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Rosen%27s+emergency+medicine%3A+concepts+and+clinical+practice&amp;rft.place=Philadelphia&amp;rft.pages=746&amp;rft.edition=7&amp;rft.pub=Mosby%2FElsevier&amp;rft.date=2010&amp;rft.isbn=978-0-323-05472-0&amp;rft.aulast=Marx&amp;rft.aufirst=JA&amp;rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3Du7TNcpCeqx8C%26pg%3DPA746&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-9">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.merriam-webster.com/dictionary/snakebite">"Definition of Snakebite"</a>. <i>www.merriam-webster.com</i><span class="reference-accessdate">. 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Prevalence of snakebite envenoming. [https://web.archive.org/web/20170922113845/http://www.who.int/snakebites/epidemiology/en/ ]. Accessed April 15, 2019</span> </li> <li id="cite_note-17"><span class="mw-cite-backlink"><b><a href="#cite_ref-17">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20170922115522/http://www.who.int/snakebites/resources/s40409-017-0127-6/en/">"WHO &#124; Snakebite envenomation turns again into a neglected tropical disease!"</a>. <i>WHO</i>. 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Emergency Medicine: A Comprehensive Study Guide. 6th ed. New York, NY: McGraw Hill; 2004. Update date: 27 February 2008. Updated by: Stephen C. Acosta, MD, Department of Emergency Medicine, Portland VA Medical Center, Portland, OR. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc. 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Retrieved <span class="nowrap">26 July</span> 2022</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=unknown&amp;rft.jtitle=eMedicineHealth&amp;rft.atitle=Symptoms+and+Signs+of+Snakebite+%28Snake+Bite%29&amp;rft.date=2021-08-06&amp;rft.aulast=Cuhna&amp;rft.aufirst=John+P.&amp;rft_id=https%3A%2F%2Fwww.emedicinehealth.com%2Fsnakebite%2Fsymptom.htm&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-SmallAnimalToxicology-30"><span class="mw-cite-backlink"><b><a href="#cite_ref-SmallAnimalToxicology_30-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFPetersonTalcott2013" class="citation journal cs1">Peterson ME, Talcott PA (2013). <a rel="nofollow" class="external text" href="https://www.sciencedirect.com/science/article/pii/B9781455707171000752">"Snake Bite: North American Pit Vipers"</a>. <i>Small Animal Toxicology</i> (3rd&#160;ed.): <span class="nowrap">783–</span>797. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FB978-1-4557-0717-1.00075-2">10.1016/B978-1-4557-0717-1.00075-2</a>. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a>&#160;<a href="/wiki/Special:BookSources/978-1-4557-0717-1" title="Special:BookSources/978-1-4557-0717-1"><bdi>978-1-4557-0717-1</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=Small+Animal+Toxicology&amp;rft.atitle=Snake+Bite%3A+North+American+Pit+Vipers&amp;rft.pages=%3Cspan+class%3D%22nowrap%22%3E783-%3C%2Fspan%3E797&amp;rft.date=2013&amp;rft_id=info%3Adoi%2F10.1016%2FB978-1-4557-0717-1.00075-2&amp;rft.isbn=978-1-4557-0717-1&amp;rft.aulast=Peterson&amp;rft.aufirst=Michael+E.&amp;rft.au=Talcott%2C+Patricia+A.&amp;rft_id=https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Farticle%2Fpii%2FB9781455707171000752&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-Phillips2002-31"><span class="mw-cite-backlink">^ <a href="#cite_ref-Phillips2002_31-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Phillips2002_31-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFPhillips2002" class="citation journal cs1">Phillips CM (2002). <a rel="nofollow" class="external text" href="http://www.kingsnake.com/aho/pdf/menu6/phillips2002.pdf">"Sea snake envenomation"</a> <span class="cs1-format">(PDF)</span>. <i>Dermatologic Therapy</i>. <b>15</b> (1): 58–61(4). <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1046%2Fj.1529-8019.2002.01504.x">10.1046/j.1529-8019.2002.01504.x</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a>&#160;<a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:73275266">73275266</a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20110428095839/http://www.kingsnake.com/aho/pdf/menu6/phillips2002.pdf">Archived</a> <span class="cs1-format">(PDF)</span> from the original on 28 April 2011<span class="reference-accessdate">. Retrieved <span class="nowrap">24 July</span> 2009</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=Dermatologic+Therapy&amp;rft.atitle=Sea+snake+envenomation&amp;rft.volume=15&amp;rft.issue=1&amp;rft.pages=58-61%284%29&amp;rft.date=2002&amp;rft_id=info%3Adoi%2F10.1046%2Fj.1529-8019.2002.01504.x&amp;rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A73275266%23id-name%3DS2CID&amp;rft.aulast=Phillips&amp;rft.aufirst=CM&amp;rft_id=http%3A%2F%2Fwww.kingsnake.com%2Faho%2Fpdf%2Fmenu6%2Fphillips2002.pdf&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-ManagementofRespiratoryFailure-32"><span class="mw-cite-backlink"><b><a href="#cite_ref-ManagementofRespiratoryFailure_32-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSabirinSudjudSuwarmanPradian2020" class="citation journal cs1">Sabirin MR, Sudjud RW, Suwarman S, Pradian E (18 August 2020). <a rel="nofollow" class="external text" href="https://ssrn.com/abstract=3676254">"Management of Respiratory Failure Following Snake Bite"</a>. <i>Journal of Health and Medical Sciences</i>. <b>3</b> (3): <span class="nowrap">338–</span>349. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.31014%2Faior.1994.03.03.129">10.31014/aior.1994.03.03.129</a>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a>&#160;<a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/2622-7258">2622-7258</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a>&#160;<a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:224885423">224885423</a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20220727124831/https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3676254">Archived</a> from the original on 27 July 2022<span class="reference-accessdate">. Retrieved <span class="nowrap">27 July</span> 2022</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=Journal+of+Health+and+Medical+Sciences&amp;rft.atitle=Management+of+Respiratory+Failure+Following+Snake+Bite&amp;rft.volume=3&amp;rft.issue=3&amp;rft.pages=%3Cspan+class%3D%22nowrap%22%3E338-%3C%2Fspan%3E349&amp;rft.date=2020-08-18&amp;rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A224885423%23id-name%3DS2CID&amp;rft.issn=2622-7258&amp;rft_id=info%3Adoi%2F10.31014%2Faior.1994.03.03.129&amp;rft.aulast=Sabirin&amp;rft.aufirst=Mira+R&amp;rft.au=Sudjud%2C+Reza+W&amp;rft.au=Suwarman%2C+Suwarman&amp;rft.au=Pradian%2C+Erwin&amp;rft_id=https%3A%2F%2Fssrn.com%2Fabstract%3D3676254&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-33"><span class="mw-cite-backlink"><b><a href="#cite_ref-33">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBhaumikKallakuriKaurDevarapalli2020" class="citation journal cs1">Bhaumik S, Kallakuri S, Kaur A, Devarapalli S, Daniel M (November 2020). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705584">"Mental health conditions after snakebite: a scoping review"</a>. <i>BMJ Global Health</i>. <b>5</b> (11): e004131. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1136%2Fbmjgh-2020-004131">10.1136/bmjgh-2020-004131</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a>&#160;<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705584">7705584</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a>&#160;<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/33257419">33257419</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=BMJ+Global+Health&amp;rft.atitle=Mental+health+conditions+after+snakebite%3A+a+scoping+review&amp;rft.volume=5&amp;rft.issue=11&amp;rft.pages=e004131&amp;rft.date=2020-11&amp;rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC7705584%23id-name%3DPMC&amp;rft_id=info%3Apmid%2F33257419&amp;rft_id=info%3Adoi%2F10.1136%2Fbmjgh-2020-004131&amp;rft.aulast=Bhaumik&amp;rft.aufirst=S&amp;rft.au=Kallakuri%2C+S&amp;rft.au=Kaur%2C+A&amp;rft.au=Devarapalli%2C+S&amp;rft.au=Daniel%2C+M&amp;rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC7705584&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-Brut2013-34"><span class="mw-cite-backlink">^ <a href="#cite_ref-Brut2013_34-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Brut2013_34-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-Brut2013_34-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFGarciaTanowitzDel_Brutto2013" class="citation book cs1">Garcia HH, Tanowitz H, Del Brutto OH (2013). Garcia HH, Tanowitz HB, Del Brutto OH (eds.). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=bJx3g30aDhIC&amp;pg=PA351"><i>Neuroparasitology and tropical neurology</i></a>. Newnes. p.&#160;351. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a>&#160;<a href="/wiki/Special:BookSources/978-0-444-53499-6" title="Special:BookSources/978-0-444-53499-6"><bdi>978-0-444-53499-6</bdi></a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20170908174306/https://books.google.com/books?id=bJx3g30aDhIC&amp;pg=PA351">Archived</a> from the original on 8 September 2017.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Neuroparasitology+and+tropical+neurology&amp;rft.pages=351&amp;rft.pub=Newnes&amp;rft.date=2013&amp;rft.isbn=978-0-444-53499-6&amp;rft.aulast=Garcia&amp;rft.aufirst=Hector+H.&amp;rft.au=Tanowitz%2C+Herbert&amp;rft.au=Del+Brutto%2C+Oscar+H.&amp;rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DbJx3g30aDhIC%26pg%3DPA351&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-35"><span class="mw-cite-backlink"><b><a href="#cite_ref-35">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFCampbellShaw1974" class="citation book cs1">Campbell S, Shaw CE (1974). <i>Snakes of The American West</i>. New York: <a href="/wiki/Alfred_A._Knopf" title="Alfred A. Knopf">Alfred A. Knopf</a>. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a>&#160;<a href="/wiki/Special:BookSources/978-0-394-48882-0" title="Special:BookSources/978-0-394-48882-0"><bdi>978-0-394-48882-0</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Snakes+of+The+American+West&amp;rft.place=New+York&amp;rft.pub=Alfred+A.+Knopf&amp;rft.date=1974&amp;rft.isbn=978-0-394-48882-0&amp;rft.aulast=Campbell&amp;rft.aufirst=Sheldon&amp;rft.au=Shaw%2C+Charles+E.&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-Young2002-36"><span class="mw-cite-backlink">^ <a href="#cite_ref-Young2002_36-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Young2002_36-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFYoungLeeDaley2002" class="citation journal cs1">Young BA, Lee CE, Daley KM (2002). <a rel="nofollow" class="external text" href="https://doi.org/10.1641%2F0006-3568%282002%29052%5B1121%3ADSMV%5D2.0.CO%3B2">"Do Snakes Meter Venom?"</a>. <i>BioScience</i>. <b>52</b> (12): <span class="nowrap">1121–</span>26. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1641%2F0006-3568%282002%29052%5B1121%3ADSMV%5D2.0.CO%3B2">10.1641/0006-3568(2002)052&#91;1121:DSMV&#93;2.0.CO&#59;2</a></span>. <q>The second major assumption that underlies venom metering is the snake's ability to accurately assess the target</q></cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=BioScience&amp;rft.atitle=Do+Snakes+Meter+Venom%3F&amp;rft.volume=52&amp;rft.issue=12&amp;rft.pages=%3Cspan+class%3D%22nowrap%22%3E1121-%3C%2Fspan%3E26&amp;rft.date=2002&amp;rft_id=info%3Adoi%2F10.1641%2F0006-3568%282002%29052%5B1121%3ADSMV%5D2.0.CO%3B2&amp;rft.aulast=Young&amp;rft.aufirst=BA&amp;rft.au=Lee%2C+CE&amp;rft.au=Daley%2C+KM&amp;rft_id=https%3A%2F%2Fdoi.org%2F10.1641%252F0006-3568%25282002%2529052%255B1121%253ADSMV%255D2.0.CO%253B2&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-Young2001-37"><span class="mw-cite-backlink"><b><a href="#cite_ref-Young2001_37-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFYoungZahn2001" class="citation journal cs1">Young BA, Zahn K (December 2001). <a rel="nofollow" class="external text" href="http://jeb.biologists.org/cgi/reprint/204/24/4345.pdf">"Venom flow in rattlesnakes: mechanics and metering"</a> <span class="cs1-format">(PDF)</span>. <i>The Journal of Experimental Biology</i>. <b>204</b> (Pt 24): <span class="nowrap">4345–</span>4351. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1242%2Fjeb.204.24.4345">10.1242/jeb.204.24.4345</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a>&#160;<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11815658">11815658</a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20090109013518/http://jeb.biologists.org/cgi/reprint/204/24/4345.pdf">Archived</a> <span class="cs1-format">(PDF)</span> from the original on 9 January 2009. <q>With the species and size of target held constant, the duration of venom flow, maximum venom flow rate and total venom volume were all significantly lower in predatory than in defensive strikes</q></cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=The+Journal+of+Experimental+Biology&amp;rft.atitle=Venom+flow+in+rattlesnakes%3A+mechanics+and+metering&amp;rft.volume=204&amp;rft.issue=Pt+24&amp;rft.pages=%3Cspan+class%3D%22nowrap%22%3E4345-%3C%2Fspan%3E4351&amp;rft.date=2001-12&amp;rft_id=info%3Adoi%2F10.1242%2Fjeb.204.24.4345&amp;rft_id=info%3Apmid%2F11815658&amp;rft.aulast=Young&amp;rft.aufirst=BA&amp;rft.au=Zahn%2C+K&amp;rft_id=http%3A%2F%2Fjeb.biologists.org%2Fcgi%2Freprint%2F204%2F24%2F4345.pdf&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-Deufel2003-38"><span class="mw-cite-backlink"><b><a href="#cite_ref-Deufel2003_38-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFDeufelCundall2003" class="citation journal cs1">Deufel A, Cundall D (2003). <a rel="nofollow" class="external text" href="https://www.academia.edu/7083466">"Feeding in Atractaspis (Serpentes: Atractaspididae): a study in conflicting functional constraints"</a>. <i>Zoology</i>. <b>106</b> (1): <span class="nowrap">43–</span>61. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2003Zool..106...43D">2003Zool..106...43D</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1078%2F0944-2006-00088">10.1078/0944-2006-00088</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a>&#160;<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16351890">16351890</a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20160107214703/http://www.academia.edu/7083466/Feeding_in_Atractaspis_-_for_analysis">Archived</a> from the original on 7 January 2016<span class="reference-accessdate">. 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href="https://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.596.5081">10.1.1.596.5081</a></span>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1081%2FTXR-120004741">10.1081/TXR-120004741</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a>&#160;<a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:86568032">86568032</a>. Archived from <a rel="nofollow" class="external text" href="http://www.unco.edu/nhs/biology/faculty_staff/mackessy/colubrid.pdf">the original</a> <span class="cs1-format">(PDF)</span> on 2 June 2010<span class="reference-accessdate">. Retrieved <span class="nowrap">26 September</span> 2009</span>. <q>Estimates of the number of venomous colubrids approach 700 species. Most may not produce a venom capable of causing serious damage to humans, but at least five species (<i>Dispholidus typus</i>, <i>Thelotornis capensis</i>, <i>Rhabdophis tigrinus</i>, <i>Philodryas olfersii</i> and <i>Tachymenis peruviana</i>) have caused human fatalities</q></cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=Journal+of+Toxicology%3A+Toxin+Reviews&amp;rft.atitle=Biochemistry+and+pharmacology+of+colubrid+snake+venoms&amp;rft.volume=21&amp;rft.issue=%3Cspan+class%3D%22nowrap%22%3E1%E2%80%93%3C%2Fspan%3E2&amp;rft.pages=%3Cspan+class%3D%22nowrap%22%3E43-%3C%2Fspan%3E83&amp;rft.date=2002&amp;rft_id=https%3A%2F%2Fciteseerx.ist.psu.edu%2Fviewdoc%2Fsummary%3Fdoi%3D10.1.1.596.5081%23id-name%3DCiteSeerX&amp;rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A86568032%23id-name%3DS2CID&amp;rft_id=info%3Adoi%2F10.1081%2FTXR-120004741&amp;rft.aulast=Mackessy&amp;rft.aufirst=SP&amp;rft_id=http%3A%2F%2Fwww.unco.edu%2Fnhs%2Fbiology%2Ffaculty_staff%2Fmackessy%2Fcolubrid.pdf&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-WingertChan1988-84"><span class="mw-cite-backlink">^ <a 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They regarded bites by horned vipers 'fy' as non-lethal, as the victims could be saved.</q></cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=QJM&amp;rft.atitle=Life-threatening+envenoming+by+the+Saharan+horned+viper+%28Cerastes+cerastes%29+causing+micro-angiopathic+haemolysis%2C+coagulopathy+and+acute+renal+failure%3A+clinical+cases+and+review&amp;rft.volume=97&amp;rft.issue=11&amp;rft.pages=%3Cspan+class%3D%22nowrap%22%3E717-%3C%2Fspan%3E727&amp;rft.date=2004-11&amp;rft_id=info%3Adoi%2F10.1093%2Fqjmed%2Fhch118&amp;rft_id=info%3Apmid%2F15496528&amp;rft.aulast=Schneemann&amp;rft.aufirst=M&amp;rft.au=Cathomas%2C+R&amp;rft.au=Laidlaw%2C+ST&amp;rft.au=El+Nahas%2C+AM&amp;rft.au=Theakston%2C+RD&amp;rft.au=Warrell%2C+DA&amp;rft_id=https%3A%2F%2Fdoi.org%2F10.1093%252Fqjmed%252Fhch118&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-94"><span class="mw-cite-backlink"><b><a href="#cite_ref-94">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFWilcox2016" class="citation book cs1">Wilcox C (9 August 2016). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=tUsBCwAAQBAJ&amp;pg=PA32"><i>Venomous: How Earth's Deadliest Creatures Mastered Biochemistry</i></a>. Farrar, Straus and Giroux. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a>&#160;<a href="/wiki/Special:BookSources/978-0-374-71221-1" title="Special:BookSources/978-0-374-71221-1"><bdi>978-0-374-71221-1</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Venomous%3A+How+Earth%27s+Deadliest+Creatures+Mastered+Biochemistry&amp;rft.pub=Farrar%2C+Straus+and+Giroux&amp;rft.date=2016-08-09&amp;rft.isbn=978-0-374-71221-1&amp;rft.aulast=Wilcox&amp;rft.aufirst=Christie&amp;rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DtUsBCwAAQBAJ%26pg%3DPA32&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-Anil2004-95"><span class="mw-cite-backlink">^ <a href="#cite_ref-Anil2004_95-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Anil2004_95-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-Anil2004_95-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFAnil2004" class="citation journal cs1">Anil A (2004). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20070718031431/http://www.geradts.com/anil/ij/vol_004_no_002/others/pg001.html">"Homicide with snakes: A distinct possibility and its medicolegal ramifications"</a>. <i>Anil Aggrawal's Internet Journal of Forensic Medicine and Toxicology</i>. <b>4</b> (2). Archived from <a rel="nofollow" class="external text" href="http://www.geradts.com/anil/ij/vol_004_no_002/others/pg001.html">the original</a> on 18 July 2007.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=Anil+Aggrawal%27s+Internet+Journal+of+Forensic+Medicine+and+Toxicology&amp;rft.atitle=Homicide+with+snakes%3A+A+distinct+possibility+and+its+medicolegal+ramifications&amp;rft.volume=4&amp;rft.issue=2&amp;rft.date=2004&amp;rft.aulast=Anil&amp;rft.aufirst=A&amp;rft_id=http%3A%2F%2Fwww.geradts.com%2Fanil%2Fij%2Fvol_004_no_002%2Fothers%2Fpg001.html&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-Smithsonian-96"><span class="mw-cite-backlink"><b><a href="#cite_ref-Smithsonian_96-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFCrawford2007" class="citation web cs1">Crawford A (1 April 2007). <a rel="nofollow" class="external text" href="http://www.smithsonianmag.com/history-archaeology/biography/cleopatra.html">"Who Was Cleopatra? 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Retrieved <span class="nowrap">4 September</span> 2009</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=unknown&amp;rft.jtitle=Smithsonian&amp;rft.atitle=Who+Was+Cleopatra%3F+Mythology%2C+propaganda%2C+Liz+Taylor+and+the+real+Queen+of+the+Nile&amp;rft.date=2007-04-01&amp;rft.aulast=Crawford&amp;rft.aufirst=A&amp;rft_id=http%3A%2F%2Fwww.smithsonianmag.com%2Fhistory-archaeology%2Fbiography%2Fcleopatra.html&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-97"><span class="mw-cite-backlink"><b><a href="#cite_ref-97">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFGrant2011" class="citation book cs1">Grant M (14 July 2011). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=7nk5AgAAQBAJ&amp;pg=PP179"><i>Cleopatra: Cleopatra</i></a>. Orion. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a>&#160;<a href="/wiki/Special:BookSources/978-1-78022-114-4" title="Special:BookSources/978-1-78022-114-4"><bdi>978-1-78022-114-4</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Cleopatra%3A+Cleopatra&amp;rft.pub=Orion&amp;rft.date=2011-07-14&amp;rft.isbn=978-1-78022-114-4&amp;rft.aulast=Grant&amp;rft.aufirst=Michael&amp;rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3D7nk5AgAAQBAJ%26pg%3DPP179&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-Warrell2009-98"><span class="mw-cite-backlink"><b><a href="#cite_ref-Warrell2009_98-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFWarrell2009" class="citation journal cs1">Warrell DA (September 2009). <a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fqjmed%2Fhcp075">"Commissioned article: management of exotic snakebites"</a>. <i>QJM</i>. <b>102</b> (9): <span class="nowrap">593–</span>601. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fqjmed%2Fhcp075">10.1093/qjmed/hcp075</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a>&#160;<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/19535618">19535618</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=QJM&amp;rft.atitle=Commissioned+article%3A+management+of+exotic+snakebites&amp;rft.volume=102&amp;rft.issue=9&amp;rft.pages=%3Cspan+class%3D%22nowrap%22%3E593-%3C%2Fspan%3E601&amp;rft.date=2009-09&amp;rft_id=info%3Adoi%2F10.1093%2Fqjmed%2Fhcp075&amp;rft_id=info%3Apmid%2F19535618&amp;rft.aulast=Warrell&amp;rft.aufirst=DA&amp;rft_id=https%3A%2F%2Fdoi.org%2F10.1093%252Fqjmed%252Fhcp075&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-Straight1994-99"><span class="mw-cite-backlink"><b><a href="#cite_ref-Straight1994_99-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFStraightGlenn1994" class="citation journal cs1">Straight RC, Glenn JL (1994). <a rel="nofollow" class="external text" href="https://ojs.lib.byu.edu/ojs/index.php/wnan/article/viewFile/545/1430">"Human fatalities caused by venomous animals in Utah, 1900–90"</a>. <i><a href="/wiki/Great_Basin_Naturalist" class="mw-redirect" title="Great Basin Naturalist">Great Basin Naturalist</a></i>. <b>53</b> (4): <span class="nowrap">390–</span>4. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.5962%2Fbhl.part.16607">10.5962/bhl.part.16607</a></span>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20111008073525/https://ojs.lib.byu.edu/ojs/index.php/wnan/article/viewFile/545/1430">Archived</a> from the original on 8 October 2011<span class="reference-accessdate">. Retrieved <span class="nowrap">4 September</span> 2009</span>. <q>A third unusual death was a tragic fatality (1987), recorded as a homicide, which resulted when a large rattlesnake (<i>G. v. lutosus</i>) bit a 22-month-old girl after the snake had been placed around her neck (Washington County). The child died in approximately 5 h.</q></cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=Great+Basin+Naturalist&amp;rft.atitle=Human+fatalities+caused+by+venomous+animals+in+Utah%2C+1900%E2%80%9390&amp;rft.volume=53&amp;rft.issue=4&amp;rft.pages=%3Cspan+class%3D%22nowrap%22%3E390-%3C%2Fspan%3E4&amp;rft.date=1994&amp;rft_id=info%3Adoi%2F10.5962%2Fbhl.part.16607&amp;rft.aulast=Straight&amp;rft.aufirst=RC&amp;rft.au=Glenn%2C+JL&amp;rft_id=https%3A%2F%2Fojs.lib.byu.edu%2Fojs%2Findex.php%2Fwnan%2Farticle%2FviewFile%2F545%2F1430&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-Strubel2008-100"><span class="mw-cite-backlink"><b><a href="#cite_ref-Strubel2008_100-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFStrubelBirkhoferEyerWerber2008" class="citation journal cs1 cs1-prop-foreign-lang-source">Strubel T, Birkhofer A, Eyer F, Werber KD, Förstl H (May 2008). "[Attempted suicide by snake bite. Case report and literature survey]" &#91;Attempted suicide by snake bite: Case report and literature survey&#93;. <i>Der Nervenarzt</i> (in German). <b>79</b> (5): <span class="nowrap">604–</span>606. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2Fs00115-008-2431-4">10.1007/s00115-008-2431-4</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a>&#160;<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18365165">18365165</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a>&#160;<a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:21805895">21805895</a>. <q>Ein etwa 20-jähriger Arbeiter wurde nach dem Biss seiner Puffotter (<i>Bitis arietans</i>) in die Hand auf die toxikologische Intensivstation aufgenommen. Zunächst berichtet der Patient, dass es beim "Melken" der Giftschlange zu dem Biss gekommen sei, erst im weiteren Verlauf räumt er einen Suizidversuch ein. Als Gründe werden Einsamkeit angeführt sowie unerträgliche Schmerzen im Penis.</q></cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=Der+Nervenarzt&amp;rft.atitle=%5BAttempted+suicide+by+snake+bite.+Case+report+and+literature+survey%5D&amp;rft.volume=79&amp;rft.issue=5&amp;rft.pages=%3Cspan+class%3D%22nowrap%22%3E604-%3C%2Fspan%3E606&amp;rft.date=2008-05&amp;rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A21805895%23id-name%3DS2CID&amp;rft_id=info%3Apmid%2F18365165&amp;rft_id=info%3Adoi%2F10.1007%2Fs00115-008-2431-4&amp;rft.aulast=Strubel&amp;rft.aufirst=T&amp;rft.au=Birkhofer%2C+A&amp;rft.au=Eyer%2C+F&amp;rft.au=Werber%2C+KD&amp;rft.au=F%C3%B6rstl%2C+H&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-101"><span class="mw-cite-backlink"><b><a href="#cite_ref-101">^</a></b></span> <span class="reference-text">Slouber, Michael. 2017. <a rel="nofollow" class="external text" href="https://www.google.com/books/edition/Early_Tantric_Medicine/tGl4DQAAQBAJ?hl=en&amp;gbpv=1&amp;dq=Tvarit%C4%81&amp;pg=PA99&amp;printsec=frontcover">Early Tantric Medicine: Snakebite, Mantras, and Healing in the Garuda Tantras</a>. Page 99. <a href="/wiki/Oxford_University_Press" title="Oxford University Press">Oxford University Press</a>.</span> </li> <li id="cite_note-102"><span class="mw-cite-backlink"><b><a href="#cite_ref-102">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFMinghuiMalecelaCookeAbela-Ridder2019" class="citation journal cs1">Minghui R, Malecela MN, Cooke E, Abela-Ridder B (July 2019). <a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS2214-109X%2819%2930225-6">"WHO's Snakebite Envenoming Strategy for prevention and control"</a>. <i>The Lancet. Global Health</i>. <b>7</b> (7): <span class="nowrap">e837 –</span> <span class="nowrap">e838</span>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS2214-109X%2819%2930225-6">10.1016/S2214-109X(19)30225-6</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a>&#160;<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/31129124">31129124</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=The+Lancet.+Global+Health&amp;rft.atitle=WHO%27s+Snakebite+Envenoming+Strategy+for+prevention+and+control&amp;rft.volume=7&amp;rft.issue=7&amp;rft.pages=%3Cspan+class%3D%22nowrap%22%3Ee837+-%3C%2Fspan%3E+%3Cspan+class%3D%22nowrap%22%3Ee838%3C%2Fspan%3E&amp;rft.date=2019-07&amp;rft_id=info%3Adoi%2F10.1016%2FS2214-109X%2819%2930225-6&amp;rft_id=info%3Apmid%2F31129124&amp;rft.aulast=Minghui&amp;rft.aufirst=R&amp;rft.au=Malecela%2C+MN&amp;rft.au=Cooke%2C+E&amp;rft.au=Abela-Ridder%2C+B&amp;rft_id=https%3A%2F%2Fdoi.org%2F10.1016%252FS2214-109X%252819%252930225-6&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-103"><span class="mw-cite-backlink"><b><a href="#cite_ref-103">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSchiermeier2019" class="citation journal cs1">Schiermeier Q (May 2019). 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(February 2019). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383867">"Strategy for a globally coordinated response to a priority neglected tropical disease: Snakebite envenoming"</a>. <i>PLOS Neglected Tropical Diseases</i>. <b>13</b> (2): e0007059. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1371%2Fjournal.pntd.0007059">10.1371/journal.pntd.0007059</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a>&#160;<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383867">6383867</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a>&#160;<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/30789906">30789906</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=PLOS+Neglected+Tropical+Diseases&amp;rft.atitle=Strategy+for+a+globally+coordinated+response+to+a+priority+neglected+tropical+disease%3A+Snakebite+envenoming&amp;rft.volume=13&amp;rft.issue=2&amp;rft.pages=e0007059&amp;rft.date=2019-02&amp;rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6383867%23id-name%3DPMC&amp;rft_id=info%3Apmid%2F30789906&amp;rft_id=info%3Adoi%2F10.1371%2Fjournal.pntd.0007059&amp;rft.aulast=Williams&amp;rft.aufirst=DJ&amp;rft.au=Faiz%2C+MA&amp;rft.au=Abela-Ridder%2C+B&amp;rft.au=Ainsworth%2C+S&amp;rft.au=Bulfone%2C+TC&amp;rft.au=Nickerson%2C+AD&amp;rft.au=Habib%2C+AG&amp;rft.au=Junghanss%2C+T&amp;rft.au=Fan%2C+HW&amp;rft.au=Turner%2C+M&amp;rft.au=Harrison%2C+RA&amp;rft.au=Warrell%2C+DA&amp;rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6383867&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-106"><span class="mw-cite-backlink"><b><a href="#cite_ref-106">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBhaumikZwiNortonJagnoor2023" class="citation journal cs1">Bhaumik S, Zwi AB, Norton R, Jagnoor J (1 August 2023). <a rel="nofollow" class="external text" href="https://gh.bmj.com/content/8/8/e011923">"How and why snakebite became a global health priority: a policy analysis"</a>. <i>BMJ Global Health</i>. <b>8</b> (8): e011923. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1136%2Fbmjgh-2023-011923">10.1136/bmjgh-2023-011923</a>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a>&#160;<a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/2059-7908">2059-7908</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a>&#160;<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445399">10445399</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a>&#160;<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/37604596">37604596</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=BMJ+Global+Health&amp;rft.atitle=How+and+why+snakebite+became+a+global+health+priority%3A+a+policy+analysis&amp;rft.volume=8&amp;rft.issue=8&amp;rft.pages=e011923&amp;rft.date=2023-08-01&amp;rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC10445399%23id-name%3DPMC&amp;rft.issn=2059-7908&amp;rft_id=info%3Apmid%2F37604596&amp;rft_id=info%3Adoi%2F10.1136%2Fbmjgh-2023-011923&amp;rft.aulast=Bhaumik&amp;rft.aufirst=Soumyadeep&amp;rft.au=Zwi%2C+Anthony+B.&amp;rft.au=Norton%2C+Robyn&amp;rft.au=Jagnoor%2C+Jagnoor&amp;rft_id=https%3A%2F%2Fgh.bmj.com%2Fcontent%2F8%2F8%2Fe011923&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-107"><span class="mw-cite-backlink"><b><a href="#cite_ref-107">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBittel" class="citation web cs1">Bittel J. <a rel="nofollow" class="external text" href="https://www.smithsonianmag.com/science-nature/animals-venom-cant-touch-180960658/">"The Animals That Venom Can't Touch"</a>. <i><a href="/wiki/Smithsonian_(magazine)" title="Smithsonian (magazine)">Smithsonian</a></i><span class="reference-accessdate">. Retrieved <span class="nowrap">29 May</span> 2018</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=unknown&amp;rft.jtitle=Smithsonian&amp;rft.atitle=The+Animals+That+Venom+Can%27t+Touch&amp;rft.aulast=Bittel&amp;rft.aufirst=J&amp;rft_id=https%3A%2F%2Fwww.smithsonianmag.com%2Fscience-nature%2Fanimals-venom-cant-touch-180960658%2F&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> <li id="cite_note-108"><span class="mw-cite-backlink"><b><a href="#cite_ref-108">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFCollins2018" class="citation news cs1">Collins B (11 February 2018). <a rel="nofollow" class="external text" href="https://www.theguardian.com/environment/2018/feb/11/poison-pass-the-man-who-became-immune-to-snake-venom-steve-ludwin">"Poison pass: the man who became immune to snake venom"</a>. <i>the Guardian</i><span class="reference-accessdate">. Retrieved <span class="nowrap">29 May</span> 2018</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=the+Guardian&amp;rft.atitle=Poison+pass%3A+the+man+who+became+immune+to+snake+venom&amp;rft.date=2018-02-11&amp;rft.aulast=Collins&amp;rft.aufirst=B&amp;rft_id=https%3A%2F%2Fwww.theguardian.com%2Fenvironment%2F2018%2Ffeb%2F11%2Fpoison-pass-the-man-who-became-immune-to-snake-venom-steve-ludwin&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></span> </li> </ol></div></div> <dl><dt>Bibliography</dt></dl> <style data-mw-deduplicate="TemplateStyles:r1239549316">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin" style=""> <ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFGreene1997" class="citation book cs1"><a href="/wiki/Harry_W._Greene" title="Harry W. Greene">Greene HW</a> (1997). <a rel="nofollow" class="external text" href="https://archive.org/details/snakesevolutiono00fogd"><i>Snakes: The Evolution of Mystery in Nature</i></a>. Berkeley, CA: University of California Press. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a>&#160;<a href="/wiki/Special:BookSources/978-0-520-20014-2" title="Special:BookSources/978-0-520-20014-2"><bdi>978-0-520-20014-2</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Snakes%3A+The+Evolution+of+Mystery+in+Nature&amp;rft.place=Berkeley%2C+CA&amp;rft.pub=University+of+California+Press&amp;rft.date=1997&amp;rft.isbn=978-0-520-20014-2&amp;rft.aulast=Greene&amp;rft.aufirst=HW&amp;rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsnakesevolutiono00fogd&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFMackessy2010" class="citation book cs1">Mackessy SP, ed. (2010). <i>Handbook of Venoms and Toxins of Reptiles</i> (2nd&#160;ed.). Boca Raton, FL: CRC Press. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a>&#160;<a href="/wiki/Special:BookSources/978-0-8493-9165-1" title="Special:BookSources/978-0-8493-9165-1"><bdi>978-0-8493-9165-1</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Handbook+of+Venoms+and+Toxins+of+Reptiles&amp;rft.place=Boca+Raton%2C+FL&amp;rft.edition=2nd&amp;rft.pub=CRC+Press&amp;rft.date=2010&amp;rft.isbn=978-0-8493-9165-1&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFValenta2010" class="citation book cs1">Valenta J (2010). <i>Venomous Snakes: Envenoming, Therapy</i> (2nd&#160;ed.). Hauppauge, NY: Nova Science Publishers. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a>&#160;<a href="/wiki/Special:BookSources/978-1-60876-618-5" title="Special:BookSources/978-1-60876-618-5"><bdi>978-1-60876-618-5</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Venomous+Snakes%3A+Envenoming%2C+Therapy&amp;rft.place=Hauppauge%2C+NY&amp;rft.edition=2nd&amp;rft.pub=Nova+Science+Publishers&amp;rft.date=2010&amp;rft.isbn=978-1-60876-618-5&amp;rft.aulast=Valenta&amp;rft.aufirst=J&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="Further_reading">Further reading</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=23" title="Edit section: Further reading"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1235681985">.mw-parser-output .side-box{margin:4px 0;box-sizing:border-box;border:1px solid #aaa;font-size:88%;line-height:1.25em;background-color:var(--background-color-interactive-subtle,#f8f9fa);display:flow-root}.mw-parser-output .side-box-abovebelow,.mw-parser-output .side-box-text{padding:0.25em 0.9em}.mw-parser-output .side-box-image{padding:2px 0 2px 0.9em;text-align:center}.mw-parser-output .side-box-imageright{padding:2px 0.9em 2px 0;text-align:center}@media(min-width:500px){.mw-parser-output .side-box-flex{display:flex;align-items:center}.mw-parser-output .side-box-text{flex:1;min-width:0}}@media(min-width:720px){.mw-parser-output .side-box{width:238px}.mw-parser-output .side-box-right{clear:right;float:right;margin-left:1em}.mw-parser-output .side-box-left{margin-right:1em}}</style><div class="side-box metadata side-box-right"><style data-mw-deduplicate="TemplateStyles:r1126788409">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style> <div class="side-box-abovebelow"> <a href="/wiki/Wikipedia:The_Wikipedia_Library" title="Wikipedia:The Wikipedia Library">Library resources</a> about <br /> <b>Snakebite</b> <hr /></div> <div class="side-box-flex"> <div class="side-box-text plainlist"><ul><li><a class="external text" href="https://ftl.toolforge.org/cgi-bin/ftl?st=wp&amp;su=Snakebite&amp;library=OLBP">Online books</a></li> <li><a class="external text" href="https://ftl.toolforge.org/cgi-bin/ftl?st=wp&amp;su=Snakebite">Resources in your library</a></li> <li><a class="external text" href="https://ftl.toolforge.org/cgi-bin/ftl?st=wp&amp;su=Snakebite&amp;library=0CHOOSE0">Resources in other libraries</a></li> </ul></div></div> </div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239549316" /><div class="refbegin refbegin-columns references-column-width" style="column-width: 30em"> <ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFCampbellLamar2004" class="citation book cs1"><a href="/wiki/Jonathan_A._Campbell" title="Jonathan A. Campbell">Campbell JA</a>, Lamar WW (2004). <i>The Venomous Reptiles of the Western Hemisphere</i>. Ithaca, NY: Cornell University Press 978-0-8014-4141-7.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=The+Venomous+Reptiles+of+the+Western+Hemisphere&amp;rft.place=Ithaca%2C+NY&amp;rft.pub=Cornell+University+Press+978-0-8014-4141-7&amp;rft.date=2004&amp;rft.aulast=Campbell&amp;rft.aufirst=JA&amp;rft.au=Lamar%2C+WW&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSpawlsBranch1995" class="citation book cs1">Spawls S, Branch B (1995). <i>The Dangerous Snakes of Africa: Natural History, Species Directory, Venoms and Snakebite</i>. Sanibel Island, FL: Ralph Curtis Publishing. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a>&#160;<a href="/wiki/Special:BookSources/978-0-88359-029-4" title="Special:BookSources/978-0-88359-029-4"><bdi>978-0-88359-029-4</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=The+Dangerous+Snakes+of+Africa%3A+Natural+History%2C+Species+Directory%2C+Venoms+and+Snakebite&amp;rft.place=Sanibel+Island%2C+FL&amp;rft.pub=Ralph+Curtis+Publishing&amp;rft.date=1995&amp;rft.isbn=978-0-88359-029-4&amp;rft.aulast=Spawls&amp;rft.aufirst=S&amp;rft.au=Branch%2C+B&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSullivanWingertNorris_Jr1995" class="citation journal cs1">Sullivan JB, Wingert WA, Norris Jr RL (1995). "North American Venomous Reptile Bites". <i>Wilderness Medicine: Management of Wilderness and Environmental Emergencies</i>. <b>3</b>: <span class="nowrap">680–</span>709.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=Wilderness+Medicine%3A+Management+of+Wilderness+and+Environmental+Emergencies&amp;rft.atitle=North+American+Venomous+Reptile+Bites.&amp;rft.volume=3&amp;rft.pages=%3Cspan+class%3D%22nowrap%22%3E680-%3C%2Fspan%3E709&amp;rft.date=1995&amp;rft.aulast=Sullivan&amp;rft.aufirst=JB&amp;rft.au=Wingert%2C+WA&amp;rft.au=Norris+Jr%2C+RL&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFThorpeWüsterMalhotra1997" class="citation book cs1">Thorpe RS, <a href="/wiki/Wolfgang_W%C3%BCster" title="Wolfgang Wüster">Wüster W</a>, Malhotra A (14 May 1997). <i>Venomous Snakes: Ecology, Evolution, and Snakebite</i>. Oxford, England: <a href="/wiki/Oxford_University_Press" title="Oxford University Press">Oxford University Press</a>. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a>&#160;<a href="/wiki/Special:BookSources/978-0-19-854986-4" title="Special:BookSources/978-0-19-854986-4"><bdi>978-0-19-854986-4</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Venomous+Snakes%3A+Ecology%2C+Evolution%2C+and+Snakebite&amp;rft.place=Oxford%2C+England&amp;rft.pub=Oxford+University+Press&amp;rft.date=1997-05-14&amp;rft.isbn=978-0-19-854986-4&amp;rft.aulast=Thorpe&amp;rft.aufirst=RS&amp;rft.au=W%C3%BCster%2C+W&amp;rft.au=Malhotra%2C+A&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Snakebite&amp;action=edit&amp;section=24" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20100506022208/http://apps.who.int/bloodproducts/snakeantivenoms/database/">WHO Snake Antivenoms Database</a></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFOrganization2016" class="citation book cs1">Organization (2016). <i>Guidelines for the management of snakebites</i>. Regional Office for South-East Asia, World Health Organization. <a href="/wiki/Hdl_(identifier)" class="mw-redirect" title="Hdl (identifier)">hdl</a>:<a rel="nofollow" class="external text" href="https://hdl.handle.net/10665%2F249547">10665/249547</a>. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a>&#160;<a href="/wiki/Special:BookSources/978-92-9022-530-0" title="Special:BookSources/978-92-9022-530-0"><bdi>978-92-9022-530-0</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Guidelines+for+the+management+of+snakebites&amp;rft.pub=Regional+Office+for+South-East+Asia%2C+World+Health+Organization&amp;rft.date=2016&amp;rft_id=info%3Ahdl%2F10665%2F249547&amp;rft.isbn=978-92-9022-530-0&amp;rft.au=Organization&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ASnakebite" class="Z3988"></span></li></ul> <div class="navbox-styles"><style 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· ";font-weight:bold}.mw-parser-output .hlist dd:last-child::after,.mw-parser-output .hlist dt:last-child::after,.mw-parser-output .hlist li:last-child::after{content:none}.mw-parser-output .hlist dd dd:first-child::before,.mw-parser-output .hlist dd dt:first-child::before,.mw-parser-output .hlist dd li:first-child::before,.mw-parser-output .hlist dt dd:first-child::before,.mw-parser-output .hlist dt dt:first-child::before,.mw-parser-output .hlist dt li:first-child::before,.mw-parser-output .hlist li dd:first-child::before,.mw-parser-output .hlist li dt:first-child::before,.mw-parser-output .hlist li li:first-child::before{content:" (";font-weight:normal}.mw-parser-output .hlist dd dd:last-child::after,.mw-parser-output .hlist dd dt:last-child::after,.mw-parser-output .hlist dd li:last-child::after,.mw-parser-output .hlist dt dd:last-child::after,.mw-parser-output .hlist dt dt:last-child::after,.mw-parser-output .hlist dt li:last-child::after,.mw-parser-output .hlist li dd:last-child::after,.mw-parser-output .hlist li dt:last-child::after,.mw-parser-output .hlist li li:last-child::after{content:")";font-weight:normal}.mw-parser-output .hlist ol{counter-reset:listitem}.mw-parser-output .hlist ol>li{counter-increment:listitem}.mw-parser-output .hlist ol>li::before{content:" "counter(listitem)"\a0 "}.mw-parser-output .hlist dd ol>li:first-child::before,.mw-parser-output .hlist dt ol>li:first-child::before,.mw-parser-output .hlist li ol>li:first-child::before{content:" ("counter(listitem)"\a0 "}</style><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /></div><div role="navigation" class="navbox" aria-label="Navbox32" style="width:100%; margin:0.5em 0 0.5em 0;;padding:3px"><table class="nowraplinks navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background: #EAECF0;color:black;">Classification</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><div style="position:relative; float:right; font-size:0.8em;"><a href="https://www.wikidata.org/wiki/Q68854" class="extiw" title="d:Q68854">D</a></div><div class="hlist" style="text-align:left;"><ul><li><b><a href="/wiki/International_Statistical_Classification_of_Diseases_and_Related_Health_Problems" class="mw-redirect" title="International Statistical Classification of Diseases and Related Health Problems">ICD</a>-<a href="/wiki/ICD-10" title="ICD-10">10</a></b>: <a rel="nofollow" class="external text" href="https://icd.who.int/browse10/2019/en#/T63.0">T63.0</a>, T14.1, W59 (nonvenomous), X20 (venomous)</li><li><b><a href="/wiki/International_Statistical_Classification_of_Diseases_and_Related_Health_Problems" class="mw-redirect" title="International Statistical Classification of Diseases and Related Health Problems">ICD</a>-<a href="/wiki/List_of_ICD-9_codes" title="List of ICD-9 codes">9-CM</a></b>: <a rel="nofollow" class="external text" href="http://www.icd9data.com/getICD9Code.ashx?icd9=989.5">989.5</a>, <a rel="nofollow" class="external text" href="http://www.icd9data.com/getICD9Code.ashx?icd9=E905.0">E905.0</a>, <a rel="nofollow" class="external text" href="http://www.icd9data.com/getICD9Code.ashx?icd9=E906.2">E906.2</a></li><li><b><a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">MeSH</a></b>: <a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?ui=D012909">D012909</a></li><li><b><a href="/wiki/Diseases_Database" title="Diseases Database">DiseasesDB</a></b>: <a rel="nofollow" class="external text" href="http://www.diseasesdatabase.com/ddb29733.htm">29733</a></li></ul></div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background: #EAECF0;color:black;">External resources</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><div class="hlist" style="text-align:left;"><ul><li><b><a href="/wiki/MedlinePlus" title="MedlinePlus">MedlinePlus</a></b>: <a rel="nofollow" class="external text" href="https://www.nlm.nih.gov/medlineplus/ency/article/000031.htm">000031</a></li><li><b><a href="/wiki/EMedicine" title="EMedicine">eMedicine</a></b>: <a rel="nofollow" class="external text" href="https://emedicine.medscape.com/med/2143-overview">med/2143</a></li><li><b>Scholia</b>: <a class="external text" href="https://tools.wmflabs.org/scholia/topic/Q68854">Q68854</a></li></ul></div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="General_wounds_and_injuries99" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><style data-mw-deduplicate="TemplateStyles:r1239400231">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}html.skin-theme-clientpref-night .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:General_injuries" title="Template:General injuries"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:General_injuries" title="Template talk:General injuries"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:General_injuries" title="Special:EditPage/Template:General injuries"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="General_wounds_and_injuries99" style="font-size:114%;margin:0 4em">General <a href="/wiki/Wound" title="Wound">wounds</a> and <a href="/wiki/Injury" title="Injury">injuries</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Abrasions</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abrasion_(medical)" class="mw-redirect" title="Abrasion (medical)">Abrasion</a> <ul><li><a href="/wiki/Avulsion_injury" title="Avulsion injury">Avulsion</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Blister" title="Blister">Blisters</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Blood_blister" title="Blood blister">Blood blister</a></li> <li><a href="/wiki/Coma_blister" title="Coma blister">Coma blister</a></li> <li><a href="/wiki/Delayed_blister" title="Delayed blister">Delayed blister</a></li> <li><a href="/wiki/Edema_blister" title="Edema blister">Edema blister</a></li> <li><a href="/wiki/Fracture_blister" title="Fracture blister">Fracture blister</a></li> <li><a href="/wiki/Friction_blister" title="Friction blister">Friction blister</a></li> <li><a href="/wiki/Sucking_blister" title="Sucking blister">Sucking blister</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Bruise" title="Bruise">Bruises</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Hematoma" title="Hematoma">Hematoma</a>/<a href="/wiki/Ecchymosis" class="mw-redirect" title="Ecchymosis">Ecchymosis</a> <ul><li><a href="/wiki/Battle%27s_sign" title="Battle&#39;s sign">Battle's sign</a></li> <li><a href="/wiki/Raccoon_eyes" title="Raccoon eyes">Raccoon eyes</a></li> <li><a href="/wiki/Black_eye" title="Black eye">Black eye</a></li> <li><a href="/wiki/Subungual_hematoma" title="Subungual hematoma">Subungual hematoma</a></li> <li><a href="/wiki/Cullen%27s_sign" title="Cullen&#39;s sign">Cullen's sign</a></li> <li><a href="/wiki/Grey_Turner%27s_sign" title="Grey Turner&#39;s sign">Grey Turner's sign</a></li> <li><a href="/wiki/Retroperitoneal_hemorrhage" class="mw-redirect" title="Retroperitoneal hemorrhage">Retroperitoneal hemorrhage</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Biting" title="Biting">Biting</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Animal_bite" title="Animal bite">Animal</a></li> <li><a href="/wiki/Insect_bites_and_stings" class="mw-redirect" title="Insect bites and stings">Insect</a></li> <li><a href="/wiki/Spider_bite" title="Spider bite">Spider</a></li> <li><a class="mw-selflink selflink">Snake</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other:</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Ballistic_trauma" class="mw-redirect" title="Ballistic trauma">Ballistic trauma</a></li> <li><a href="/wiki/Stab_wound" title="Stab wound">Stab wound</a></li> <li><a href="/wiki/Splinter" title="Splinter">Splinter</a></li> <li><a href="/wiki/Blunt_trauma" title="Blunt trauma">Blunt trauma</a>/superficial/<a href="/wiki/Wound#Closed" title="Wound">closed</a></li> <li><a href="/wiki/Penetrating_trauma" title="Penetrating trauma">Penetrating trauma</a>/<a href="/wiki/Wound#Open" title="Wound">open</a></li> <li><a href="/wiki/Aerosol_burn" title="Aerosol burn">Aerosol burn</a></li> <li><a href="/wiki/Burn" title="Burn">Burn</a>/<a href="/wiki/Corrosion" title="Corrosion">Corrosion</a>/<a href="/wiki/Chemical_burn" title="Chemical burn">Chemical burn</a></li> <li><a href="/wiki/Frostbite" title="Frostbite">Frostbite</a></li> <li><a href="/wiki/Occupational_injury" title="Occupational injury">Occupational injuries</a></li> <li><a href="/wiki/Amputation#Trauma" title="Amputation">Traumatic amputation</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">By region</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Hand_injury" title="Hand injury">Hand injury</a></li> <li><a href="/wiki/Head_injury" title="Head injury">Head injury</a></li> <li><a href="/wiki/Chest_injury" title="Chest injury">Chest trauma</a></li> <li><a href="/wiki/Abdominal_trauma" title="Abdominal trauma">Abdominal trauma</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="*_Poisoning_*_Toxicity_*_Overdose1265" style="padding:3px"><table class="nowraplinks hlist mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231" /><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Poisoning_and_toxicity" title="Template:Poisoning and toxicity"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Poisoning_and_toxicity" title="Template talk:Poisoning and toxicity"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Poisoning_and_toxicity" title="Special:EditPage/Template:Poisoning and toxicity"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="*_Poisoning_*_Toxicity_*_Overdose1265" class="hlist" style="font-size:114%;margin:0 4em"> <ul><li><a href="/wiki/Poisoning" title="Poisoning">Poisoning</a></li> <li><a href="/wiki/Toxicity" title="Toxicity">Toxicity</a></li> <li><a href="/wiki/Drug_overdose" title="Drug overdose">Overdose</a></li></ul> </div></th></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <ul><li><a href="/wiki/Poison" title="Poison">Poison</a></li> <li><a href="/wiki/History_of_poison" title="History of poison">History</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Inorganic_chemistry" title="Inorganic chemistry">Inorganic</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Metal" title="Metal">Metals</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Toxic_metal" class="mw-redirect" title="Toxic metal">Toxic metals</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Beryllium_poisoning" title="Beryllium poisoning">Beryllium</a></li> <li><a href="/wiki/Cadmium_poisoning" title="Cadmium poisoning">Cadmium</a></li> <li><a href="/wiki/Lead_poisoning" title="Lead poisoning">Lead</a></li> <li><a href="/wiki/Mercury_poisoning" title="Mercury poisoning">Mercury</a></li> <li><a href="/wiki/Nickel#Toxicity" title="Nickel">Nickel</a></li> <li><a href="/wiki/Thallium_poisoning" title="Thallium poisoning">Thallium</a></li> <li><a href="/wiki/Tin_poisoning" title="Tin poisoning">Tin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Dietary_mineral" class="mw-redirect" title="Dietary mineral">Dietary minerals</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Chromium_toxicity" title="Chromium toxicity">Chromium</a></li> <li><a href="/wiki/Cobalt_poisoning" title="Cobalt poisoning">Cobalt</a></li> <li><a href="/wiki/Copper_toxicity" title="Copper toxicity">Copper</a></li> <li><a href="/wiki/Iron_poisoning" title="Iron poisoning">Iron</a></li> <li><a href="/wiki/Manganism" title="Manganism">Manganese</a></li> <li><a href="/wiki/Zinc_toxicity" title="Zinc toxicity">Zinc</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other non-toxic metals</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Argyria" title="Argyria">Silver</a><sup>1</sup></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Metalloid" title="Metalloid">Metalloids</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Arsenic_poisoning" title="Arsenic poisoning">Arsenic</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Nonmetal_(chemistry)" class="mw-redirect" title="Nonmetal (chemistry)">Nonmetals</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Sulfuric_acid_poisoning" title="Sulfuric acid poisoning">Sulfuric acid</a></li> <li><a href="/wiki/Selenium#Toxicity" title="Selenium">Selenium</a></li> <li><a href="/wiki/Chlorine_gas_poisoning" title="Chlorine gas poisoning">Chlorine</a></li> <li><a href="/wiki/Fluoride_toxicity" title="Fluoride toxicity">Fluoride</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Organic_compound" title="Organic compound">Organic</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Phosphorus" title="Phosphorus">Phosphorus</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Pesticide_poisoning" title="Pesticide poisoning">Pesticides</a> <ul><li><a href="/wiki/Aluminium_phosphide_poisoning" title="Aluminium phosphide poisoning">Aluminium phosphide</a></li> <li><a href="/wiki/Organophosphate_poisoning" title="Organophosphate poisoning">Organophosphates</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Nitrogen" title="Nitrogen">Nitrogen</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cyanide_poisoning" title="Cyanide poisoning">Cyanide</a></li> <li><a href="/wiki/Nicotine_poisoning" title="Nicotine poisoning">Nicotine</a></li> <li><a href="/wiki/Nitrogen_dioxide_poisoning" title="Nitrogen dioxide poisoning">Nitrogen dioxide poisoning</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">CHO</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Alcohol_(chemistry)" title="Alcohol (chemistry)">alcohol</a></i> <ul><li><a href="/wiki/Short-term_effects_of_alcohol_consumption#Excessive_doses" title="Short-term effects of alcohol consumption">Ethanol</a></li> <li><a href="/wiki/Ethylene_glycol_poisoning" title="Ethylene glycol poisoning">Ethylene glycol</a></li> <li><a href="/wiki/Methanol_toxicity" title="Methanol toxicity">Methanol</a></li></ul></li> <li><a href="/wiki/Carbon_monoxide_poisoning" title="Carbon monoxide poisoning">Carbon monoxide</a></li> <li><a href="/wiki/Oxygen_toxicity" title="Oxygen toxicity">Oxygen</a></li> <li><a href="/wiki/Toluene_toxicity" title="Toluene toxicity">Toluene</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Pharmaceutical_drug" class="mw-redirect" title="Pharmaceutical drug">Pharmaceutical</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th id="Drug_overdoses39" scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Drug_overdose" title="Drug overdose">Drug overdoses</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Nervous_system" title="Nervous system">Nervous</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Alcohol_intoxication" title="Alcohol intoxication">Alcohol</a></li> <li><a href="/wiki/Anticholinesterase_poisoning" class="mw-redirect" title="Anticholinesterase poisoning">Anticholinesterase</a></li> <li><a href="/wiki/Aspirin_poisoning" class="mw-redirect" title="Aspirin poisoning">Aspirin</a></li> <li><a href="/wiki/Barbiturate_overdose" title="Barbiturate overdose">Barbiturates</a></li> <li><a href="/wiki/Benzodiazepine_overdose" title="Benzodiazepine overdose">Benzodiazepines</a></li> <li><a href="/wiki/Cocaine_toxicity" class="mw-redirect" title="Cocaine toxicity">Cocaine</a></li> <li><a href="/wiki/Lithium_toxicity" title="Lithium toxicity">Lithium</a></li> <li><a href="/wiki/Opioid_overdose" title="Opioid overdose">Opioids</a></li> <li><a href="/wiki/Paracetamol_poisoning" title="Paracetamol poisoning">Paracetamol</a></li> <li><a href="/wiki/Serotonin_syndrome" title="Serotonin syndrome">Serotonergic substances</a></li> <li><a href="/wiki/Tricyclic_antidepressant_overdose" title="Tricyclic antidepressant overdose">Tricyclic antidepressants</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cardiovascular_system" class="mw-redirect" title="Cardiovascular system">Cardiovascular</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Digoxin_toxicity" title="Digoxin toxicity">Digoxin</a></li> <li><a href="/wiki/Dipyridamole#Overdose" title="Dipyridamole">Dipyridamole</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Vitamin_poisoning" class="mw-redirect" title="Vitamin poisoning">Vitamin poisoning</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Hypervitaminosis_A" title="Hypervitaminosis A">Vitamin A</a></li> <li><a href="/wiki/Hypervitaminosis_D" class="mw-redirect" title="Hypervitaminosis D">Vitamin D</a></li> <li><a href="/wiki/Hypervitaminosis_E" class="mw-redirect" title="Hypervitaminosis E">Vitamin E</a></li> <li><a href="/wiki/Megavitamin-B6_syndrome" title="Megavitamin-B6 syndrome">Megavitamin-B<sub>6</sub> syndrome</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Biological<sup>2</sup></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Venomous_fish" title="Venomous fish">Fish</a>&#160;/ <a href="/wiki/Seafood" title="Seafood">Seafood</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Ciguatera" class="mw-redirect" title="Ciguatera">Ciguatera</a></li> <li><a href="/wiki/Haff_disease" title="Haff disease">Haff disease</a></li> <li><a href="/wiki/Ichthyoallyeinotoxism" title="Ichthyoallyeinotoxism">Ichthyoallyeinotoxism</a></li> <li><a href="/wiki/Scombroid_food_poisoning" title="Scombroid food poisoning">Scombroid</a></li> <li><a href="/wiki/Shellfish_poisoning" title="Shellfish poisoning">Shellfish poisoning</a> <ul><li><a href="/wiki/Amnesic_shellfish_poisoning" title="Amnesic shellfish poisoning">Amnesic</a></li> <li><a href="/wiki/Diarrhetic_shellfish_poisoning" class="mw-redirect" title="Diarrhetic shellfish poisoning">Diarrhetic</a></li> <li><a href="/wiki/Neurotoxic_shellfish_poisoning" title="Neurotoxic shellfish poisoning">Neurotoxic</a></li> <li><a href="/wiki/Paralytic_shellfish_poisoning" title="Paralytic shellfish poisoning">Paralytic</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other <a href="/wiki/Vertebrate" title="Vertebrate">vertebrates</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Poisonous_amphibian" title="Poisonous amphibian">Amphibian</a> <ul><li><a href="/wiki/Batrachotoxin" title="Batrachotoxin">Batrachotoxin</a></li> <li><a href="/wiki/Bombesin" title="Bombesin">Bombesin</a></li> <li><a href="/wiki/Bufotenin" title="Bufotenin">Bufotenin</a></li> <li><a href="/wiki/Physalaemin" title="Physalaemin">Physalaemin</a></li></ul></li> <li><a href="/wiki/Toxic_bird" title="Toxic bird">Birds</a> <ul><li><a href="/wiki/Coturnism" title="Coturnism">Coturnism</a></li></ul></li> <li><a href="/wiki/Venomous_mammal" title="Venomous mammal">Mammal</a></li> <li><a href="/wiki/Venomous_snake" title="Venomous snake">Snakes</a>&#160;/ <a href="/wiki/Snake_venom" title="Snake venom">Snake venom</a> <ul><li><a href="/wiki/Alpha-Bungarotoxin" class="mw-redirect" title="Alpha-Bungarotoxin">Alpha-Bungarotoxin</a></li> <li><a href="/wiki/Ancrod" title="Ancrod">Ancrod</a></li> <li><a href="/wiki/Batroxobin" title="Batroxobin">Batroxobin</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Arthropod" title="Arthropod">Arthropods</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Arthropod_bites_and_stings" title="Arthropod bites and stings">Arthropod bites and stings</a></li> <li><a href="/wiki/Bee_sting" title="Bee sting">Bee sting</a>&#160;/ <a href="/wiki/Apitoxin" title="Apitoxin">Bee venom</a> <ul><li><a href="/wiki/Apamin" title="Apamin">Apamin</a></li> <li><a href="/wiki/Melittin" title="Melittin">Melittin</a></li></ul></li> <li><a href="/wiki/Scorpion_venom" class="mw-redirect" title="Scorpion venom">Scorpion venom</a> <ul><li><a href="/wiki/Charybdotoxin" title="Charybdotoxin">Charybdotoxin</a></li></ul></li> <li><a href="/wiki/Spider_bite" title="Spider bite">spider venom</a> <ul><li><a href="/wiki/Latrotoxin" title="Latrotoxin">Latrotoxin</a>&#160;/ <a href="/wiki/Latrodectism" title="Latrodectism">Latrodectism</a></li> <li><a href="/wiki/Loxoscelism" title="Loxoscelism">Loxoscelism</a></li></ul></li> <li><a href="/wiki/Tick_paralysis" title="Tick paralysis">Tick paralysis</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/List_of_poisonous_plants" title="List of poisonous plants">Plants</a>&#160;/ <a href="/wiki/List_of_poisonous_fungus_species" title="List of poisonous fungus species">Fungi</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cinchonism" title="Cinchonism">Cinchonism</a></li> <li><a href="/wiki/Ergotism" title="Ergotism">Ergotism</a></li> <li><a href="/wiki/Fish_toxins" title="Fish toxins">Fish toxins</a></li> <li><a href="/wiki/Lathyrism" title="Lathyrism">Lathyrism</a></li> <li><a href="/wiki/Locoweed" title="Locoweed">Locoism</a></li> <li><a href="/wiki/Mushroom_poisoning" title="Mushroom poisoning">Mushroom</a></li> <li><a href="/wiki/Strychnine_poisoning" title="Strychnine poisoning">Strychnine</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Related topics</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Animal_bite" title="Animal bite">Bite</a> and <a href="/wiki/Stinger" title="Stinger">Stinger</a> <ul><li><a href="/wiki/Stinging_plant" title="Stinging plant">plant</a></li></ul></li> <li><a href="/wiki/Cnidocyte" title="Cnidocyte">Cnidocyte</a></li> <li><a href="/wiki/List_of_venomous_animals" title="List of venomous animals">Venomous animals</a></li> <li><a href="/wiki/List_of_poisonous_animals" title="List of poisonous animals">Poisonous animals</a></li> <li><a href="/wiki/List_of_deadly_fungus_species" title="List of deadly fungus species">Deadly fungus</a></li> <li><a href="/wiki/Mycotoxicology" title="Mycotoxicology">Mycotoxicology</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Miscellaneous</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Antibiotic" title="Antibiotic">Antibiotic</a></li> <li><a href="/wiki/EPA_list_of_extremely_hazardous_substances" title="EPA list of extremely hazardous substances">EPA list of hazard</a></li> <li><a href="/wiki/Lists_of_poisonings" title="Lists of poisonings">Lists of poisonings</a></li> <li><a href="/wiki/List_of_types_of_poison" title="List of types of poison">List of types of poison</a></li> <li><a href="/wiki/Pollution" title="Pollution">Pollution</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background: transparent; padding: 0px;"><div></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><td class="navbox-abovebelow" colspan="2"><div id="1Silver_is_generally_non-toxic_metal,_but_in_large_doses_it_can_lead_to_argyria,_which_is_rare._2_including_venoms,_toxins,_foodborne_illnesses.190"><sup>1</sup><a href="/wiki/Silver" title="Silver">Silver</a> is generally non-toxic metal, but in large doses it can lead to <a href="/wiki/Argyria" title="Argyria">argyria</a>, which is rare.<br /> <sup>2</sup> including <a href="/wiki/Venom" title="Venom">venoms</a>, <a href="/wiki/Toxin" title="Toxin">toxins</a>, <a href="/wiki/Foodborne_illness" title="Foodborne illness">foodborne illnesses</a>.</div></td></tr><tr><td colspan="2" class="navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><span class="noviewer" typeof="mw:File"><span title="Category"><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/16px-Symbol_category_class.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/23px-Symbol_category_class.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/31px-Symbol_category_class.svg.png 2x" data-file-width="180" data-file-height="185" /></span></span> <b><a href="/wiki/Category:Toxicology" title="Category:Toxicology">Category</a></b></li> <li><span class="noviewer" typeof="mw:File"><span title="Commons page"><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/20px-Commons-logo.svg.png" decoding="async" width="12" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/40px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></span></span> <b><a href="https://commons.wikimedia.org/wiki/Category:Toxicology" class="extiw" title="commons:Category:Toxicology">Commons</a></b></li> <li><span class="noviewer" typeof="mw:File"><span title="WikiProject"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/37/People_icon.svg/16px-People_icon.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/37/People_icon.svg/24px-People_icon.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/37/People_icon.svg/32px-People_icon.svg.png 2x" data-file-width="100" data-file-height="100" /></span></span> <b><a href="/wiki/Wikipedia:WikiProject_Toxicology" class="mw-redirect" title="Wikipedia:WikiProject Toxicology">WikiProject</a></b></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="Animal_bites_and_stings181" style="padding:3px"><table class="nowraplinks hlist mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231" /><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Animal_bites_and_stings" title="Template:Animal bites and stings"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Animal_bites_and_stings" title="Template talk:Animal bites and stings"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Animal_bites_and_stings" title="Special:EditPage/Template:Animal bites and stings"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Animal_bites_and_stings181" style="font-size:114%;margin:0 4em"><a href="/wiki/Animal_bite" title="Animal bite">Animal bites</a> and <a href="/wiki/Stinger" title="Stinger">stings</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Invertebrate</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Arthropod_bites_and_stings" title="Arthropod bites and stings">Arthropod</a> <ul><li><a href="/wiki/Centipede_bite" title="Centipede bite">Centipede</a></li> <li><a href="/wiki/Insect_bites_and_stings" class="mw-redirect" title="Insect bites and stings">Insect</a> <ul><li><a href="/wiki/Ant_venom" title="Ant venom">Ant</a></li> <li><a href="/wiki/Bed_bug_infestation" class="mw-redirect" title="Bed bug infestation">Bed bug <i>cimicosis</i></a></li> <li><a href="/wiki/Bee_sting" title="Bee sting">Bee</a></li> <li><a href="/wiki/Pulicosis" title="Pulicosis">Flea <i>pulicosis</i></a></li> <li><a href="/wiki/Mosquito_bite" class="mw-redirect" title="Mosquito bite">Mosquito</a></li></ul></li> <li><a href="/wiki/Scorpion_sting" title="Scorpion sting">Scorpion <i>scorpionism</i></a></li> <li><a href="/wiki/Demodicosis" title="Demodicosis">Skin mite <i>demodicosis</i></a></li> <li><a href="/wiki/Spider_bite" title="Spider bite">Spider <i>arachnidism</i></a> <ul><li><a href="/wiki/Latrodectism" title="Latrodectism">Black widow spider <i>latrodectism</i></a></li> <li><a href="/wiki/Loxoscelism" title="Loxoscelism">Recluse spider <i>loxoscelism</i></a></li></ul></li> <li><a href="/wiki/Millipede_burn" title="Millipede burn">Millipede</a></li></ul></li> <li><a href="/wiki/Bristleworm_sting" class="mw-redirect" title="Bristleworm sting">Bristleworm</a></li> <li><a href="/wiki/Cephalopod_attack" title="Cephalopod attack">Cephalopod</a></li> <li><a href="/wiki/Coral_dermatitis" title="Coral dermatitis">Coral</a></li> <li><a href="/wiki/Jellyfish_dermatitis" title="Jellyfish dermatitis">Jellyfish</a></li> <li><a href="/wiki/Sea_anemone_dermatitis" title="Sea anemone dermatitis">Sea anemone</a></li> <li><a href="/wiki/Sea_urchin_injury" title="Sea urchin injury">Sea urchin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Vertebrate</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/List_of_fatal_alligator_attacks_in_the_United_States" title="List of fatal alligator attacks in the United States">Alligator</a></li> <li><a href="/wiki/Bear_attack" title="Bear attack">Bear</a></li> <li><a href="/wiki/Beaver_attack" title="Beaver attack">Beaver</a></li> <li><a href="/wiki/List_of_fatal_cougar_attacks_in_North_America" title="List of fatal cougar attacks in North America">Cougar</a></li> <li><a href="/wiki/Coyote_attack" title="Coyote attack">Coyote</a></li> <li><a href="/wiki/Crocodile_attack" title="Crocodile attack">Crocodile</a></li> <li><a href="/wiki/Cat_bite" title="Cat bite">Domestic cat</a></li> <li><a href="/wiki/Orca_attacks" title="Orca attacks">Orca</a></li> <li><a href="/wiki/Leopard_attack" title="Leopard attack">Leopard</a></li> <li><a href="/wiki/Monkey_bite" title="Monkey bite">Monkey</a></li> <li><a href="/wiki/Shark_attack" title="Shark attack">Shark</a></li> <li><a class="mw-selflink selflink">Snake</a></li> <li><a href="/wiki/Stingray_injury" title="Stingray injury">Stingray</a></li> <li><a href="/wiki/Tiger_attack" title="Tiger attack">Tiger</a></li> <li><a href="/wiki/Venomous_fish" title="Venomous fish">Venomous fish</a></li> <li><a href="/wiki/Walrus_attack" title="Walrus attack">Walrus</a></li> <li><a href="/wiki/Wolf_attacks_on_humans" class="mw-redirect" title="Wolf attacks on humans">Wolf</a> <ul><li><a href="/wiki/Dog_bite" title="Dog bite">Dog</a> <ul><li><a href="/wiki/Dingo_attack" title="Dingo attack">Dingo</a></li></ul></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Animal_attack" title="Animal attack">Animal attack</a></li> <li><a href="/wiki/Cnidocyte" title="Cnidocyte">Cnidocyte</a></li> <li><a href="/wiki/Man-eating_animal" title="Man-eating animal">Man-eating animal</a></li> <li><a href="/wiki/Stinging_plant" title="Stinging plant">Stinging plant</a></li> <li><a href="/wiki/Seabather%27s_eruption" title="Seabather&#39;s eruption">Seabather's eruption</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <ul><li><span class="noviewer" typeof="mw:File"><span title="Category"><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/16px-Symbol_category_class.svg.png" decoding="async" width="16" 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href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231" /><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Reptiles_in_culture" title="Template:Reptiles in culture"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Reptiles_in_culture" title="Template talk:Reptiles in culture"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Reptiles_in_culture" title="Special:EditPage/Template:Reptiles in culture"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Reptiles_in_culture84" style="font-size:114%;margin:0 4em"><a href="/wiki/Reptiles_in_culture" class="mw-redirect" title="Reptiles in culture">Reptiles in culture</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cultural_depictions_of_dinosaurs" title="Cultural depictions of dinosaurs">Dinosaurs</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Crystal_Palace_Dinosaurs" title="Crystal Palace Dinosaurs">Crystal Palace Dinosaurs</a></li> <li><i><a href="/wiki/Jurassic_Park" title="Jurassic Park">Jurassic Park</a></i></li> <li><a href="/wiki/Stegosaurus_in_popular_culture" title="Stegosaurus in popular culture">Stegosaurus in popular culture</a></li> <li><a href="/wiki/Tyrannosaurus_in_popular_culture" title="Tyrannosaurus in popular culture">Tyrannosaurus in popular culture</a></li></ul> </div></td><td class="noviewer navbox-image" rowspan="3" style="width:1px;padding:0 0 0 2px"><div><span typeof="mw:File"><a href="/wiki/File:Charmeur_de_serpents_%C3%A0_Jaipur_(2).JPG" class="mw-file-description"><img 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href="/wiki/Help:Authority_control" title="Help:Authority control">Authority control databases</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q68854#identifiers" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><ul><li><span class="uid"><a rel="nofollow" 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