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id="toc-Insertion_of_intrauterine_contraceptive_device" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Insertion_of_intrauterine_contraceptive_device"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.7</span> <span>Insertion of intrauterine contraceptive device</span> </div> </a> <ul id="toc-Insertion_of_intrauterine_contraceptive_device-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Other" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Other"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.8</span> <span>Other</span> </div> </a> <ul id="toc-Other-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Adverse_effects" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Adverse_effects"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Adverse effects</span> </div> </a> <ul id="toc-Adverse_effects-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Contraindications" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Contraindications"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Contraindications</span> </div> </a> <ul id="toc-Contraindications-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Pharmacology" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Pharmacology"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Pharmacology</span> </div> </a> <button aria-controls="toc-Pharmacology-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Pharmacology subsection</span> </button> <ul id="toc-Pharmacology-sublist" class="vector-toc-list"> <li id="toc-Mechanism_of_action" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Mechanism_of_action"> <div class="vector-toc-text"> <span class="vector-toc-numb">4.1</span> <span>Mechanism of action</span> </div> </a> <ul id="toc-Mechanism_of_action-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Society_and_culture" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Society_and_culture"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Society and culture</span> </div> </a> <button aria-controls="toc-Society_and_culture-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Society and culture subsection</span> </button> <ul id="toc-Society_and_culture-sublist" class="vector-toc-list"> <li id="toc-Black_market" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Black_market"> <div class="vector-toc-text"> <span class="vector-toc-numb">5.1</span> <span>Black market</span> </div> </a> <ul id="toc-Black_market-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>References</span> </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contents" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" 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Available in 28 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-28" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">28 languages</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-af mw-list-item"><a href="https://af.wikipedia.org/wiki/Misoprostol" title="Misoprostol – Afrikaans" lang="af" hreflang="af" data-title="Misoprostol" data-language-autonym="Afrikaans" data-language-local-name="Afrikaans" class="interlanguage-link-target"><span>Afrikaans</span></a></li><li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%85%D9%8A%D8%B2%D9%88%D8%A8%D8%B1%D9%88%D8%B3%D8%AA%D9%88%D9%84" title="ميزوبروستول – Arabic" lang="ar" hreflang="ar" data-title="ميزوبروستول" data-language-autonym="العربية" data-language-local-name="Arabic" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-ast mw-list-item"><a href="https://ast.wikipedia.org/wiki/Misoprostol" title="Misoprostol – Asturian" lang="ast" hreflang="ast" data-title="Misoprostol" data-language-autonym="Asturianu" data-language-local-name="Asturian" class="interlanguage-link-target"><span>Asturianu</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D9%85%DB%8C%D8%B2%D9%88%D9%BE%D8%B1%D8%B3%D8%AA%D9%88%D9%84" title="میزوپرستول – South Azerbaijani" lang="azb" hreflang="azb" data-title="میزوپرستول" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Misoprostol" title="Misoprostol – German" lang="de" hreflang="de" data-title="Misoprostol" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%9C%CE%B9%CF%83%CE%BF%CF%80%CF%81%CE%BF%CF%83%CF%84%CF%8C%CE%BB%CE%B7" title="Μισοπροστόλη – Greek" lang="el" hreflang="el" data-title="Μισοπροστόλη" data-language-autonym="Ελληνικά" data-language-local-name="Greek" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Misoprostol" title="Misoprostol – Spanish" lang="es" hreflang="es" data-title="Misoprostol" data-language-autonym="Español" data-language-local-name="Spanish" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Misoprostolo" title="Misoprostolo – Esperanto" lang="eo" hreflang="eo" data-title="Misoprostolo" data-language-autonym="Esperanto" data-language-local-name="Esperanto" class="interlanguage-link-target"><span>Esperanto</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%85%DB%8C%D8%B2%D9%88%D9%BE%D8%B1%D8%B3%D8%AA%D9%88%D9%84" title="میزوپرستول – Persian" lang="fa" hreflang="fa" data-title="میزوپرستول" data-language-autonym="فارسی" data-language-local-name="Persian" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Misoprostol" title="Misoprostol – French" lang="fr" hreflang="fr" data-title="Misoprostol" data-language-autonym="Français" data-language-local-name="French" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D5%84%D5%AB%D5%A6%D5%B8%D5%BA%D6%80%D5%B8%D5%BD%D5%BF%D5%B8%D5%AC" title="Միզոպրոստոլ – Armenian" lang="hy" hreflang="hy" data-title="Միզոպրոստոլ" data-language-autonym="Հայերեն" data-language-local-name="Armenian" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Misoprostol" title="Misoprostol – Indonesian" lang="id" hreflang="id" data-title="Misoprostol" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonesian" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Misoprostolo" title="Misoprostolo – Italian" lang="it" hreflang="it" data-title="Misoprostolo" data-language-autonym="Italiano" data-language-local-name="Italian" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-mr mw-list-item"><a href="https://mr.wikipedia.org/wiki/%E0%A4%AE%E0%A4%BF%E0%A4%B8%E0%A5%8B%E0%A4%AA%E0%A5%8D%E0%A4%B0%E0%A5%8B%E0%A4%B8%E0%A5%8D%E0%A4%9F%E0%A5%89%E0%A4%B2" title="मिसोप्रोस्टॉल – Marathi" lang="mr" hreflang="mr" data-title="मिसोप्रोस्टॉल" data-language-autonym="मराठी" data-language-local-name="Marathi" class="interlanguage-link-target"><span>मराठी</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Misoprostol" title="Misoprostol – Dutch" lang="nl" hreflang="nl" data-title="Misoprostol" data-language-autonym="Nederlands" data-language-local-name="Dutch" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%83%9F%E3%82%BD%E3%83%97%E3%83%AD%E3%82%B9%E3%83%88%E3%83%BC%E3%83%AB" title="ミソプロストール – Japanese" lang="ja" hreflang="ja" data-title="ミソプロストール" data-language-autonym="日本語" data-language-local-name="Japanese" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%AE%E0%AC%BF%E0%AC%B8%E0%AD%8B%E0%AC%AA%E0%AD%8D%E0%AC%B0%E0%AD%8B%E0%AC%B8%E0%AD%8D%E0%AC%9F%E0%AC%B2" title="ମିସୋପ୍ରୋସ୍ଟଲ – Odia" lang="or" hreflang="or" data-title="ମିସୋପ୍ରୋସ୍ଟଲ" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="Odia" class="interlanguage-link-target"><span>ଓଡ଼ିଆ</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Mizoprostol" title="Mizoprostol – Polish" lang="pl" hreflang="pl" data-title="Mizoprostol" data-language-autonym="Polski" data-language-local-name="Polish" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Misoprostol" title="Misoprostol – Portuguese" lang="pt" hreflang="pt" data-title="Misoprostol" data-language-autonym="Português" data-language-local-name="Portuguese" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Misoprostol" title="Misoprostol – Romanian" lang="ro" hreflang="ro" data-title="Misoprostol" data-language-autonym="Română" data-language-local-name="Romanian" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9C%D0%B8%D0%B7%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%82%D0%BE%D0%BB" title="Мизопростол – Russian" lang="ru" hreflang="ru" data-title="Мизопростол" data-language-autonym="Русский" data-language-local-name="Russian" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Mizoprostol" title="Mizoprostol – Serbian" lang="sr" hreflang="sr" data-title="Mizoprostol" data-language-autonym="Српски / srpski" data-language-local-name="Serbian" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Mizoprostol" title="Mizoprostol – Serbo-Croatian" lang="sh" hreflang="sh" data-title="Mizoprostol" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="Serbo-Croatian" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Misoprostoli" title="Misoprostoli – Finnish" lang="fi" hreflang="fi" data-title="Misoprostoli" data-language-autonym="Suomi" data-language-local-name="Finnish" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Misoprostol" title="Misoprostol – Turkish" lang="tr" hreflang="tr" data-title="Misoprostol" data-language-autonym="Türkçe" data-language-local-name="Turkish" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%9C%D1%96%D0%B7%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%82%D0%BE%D0%BB" title="Мізопростол – Ukrainian" lang="uk" hreflang="uk" data-title="Мізопростол" data-language-autonym="Українська" data-language-local-name="Ukrainian" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Misoprostol" title="Misoprostol – Vietnamese" lang="vi" hreflang="vi" data-title="Misoprostol" data-language-autonym="Tiếng Việt" data-language-local-name="Vietnamese" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E7%B1%B3%E7%B4%A2%E5%89%8D%E5%88%97%E9%86%87" title="米索前列醇 – Chinese" lang="zh" hreflang="zh" data-title="米索前列醇" data-language-autonym="中文" data-language-local-name="Chinese" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q416025#sitelinks-wikipedia" title="Edit interlanguage links" class="wbc-editpage">Edit links</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Namespaces"> <div id="p-associated-pages" 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.infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox" style="border-spacing:2px;"><caption class="infobox-title"><span title="International nonproprietary name (INN): Misoprostol">Misoprostol</span></caption><tbody><tr><td colspan="2" class="infobox-image notheme" style="background-color: #f8f9fa;"><span typeof="mw:File"><a href="/wiki/File:Misoprostol.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/b/bf/Misoprostol.svg/200px-Misoprostol.svg.png" decoding="async" width="200" height="109" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/bf/Misoprostol.svg/300px-Misoprostol.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/bf/Misoprostol.svg/400px-Misoprostol.svg.png 2x" data-file-width="238" data-file-height="130" /></a></span></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Clinical data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Drug_nomenclature#Trade_names" title="Drug nomenclature">Trade names</a></th><td class="infobox-data">Cytotec, Misodel, others</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/American_Society_of_Health-System_Pharmacists" title="American Society of Health-System Pharmacists">AHFS</a>/<a href="/wiki/Drugs.com" title="Drugs.com">Drugs.com</a></th><td class="infobox-data"><span title="www.drugs.com"><a rel="nofollow" class="external text" href="https://www.drugs.com/monograph/misoprostol.html">Monograph</a></span></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/MedlinePlus" title="MedlinePlus">MedlinePlus</a></th><td class="infobox-data"><span title="medlineplus.gov"><a rel="nofollow" class="external text" href="https://medlineplus.gov/druginfo/meds/a689009.html">a689009</a></span></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Regulation_of_therapeutic_goods" title="Regulation of therapeutic goods">License data</a></th><td class="infobox-data"><style data-mw-deduplicate="TemplateStyles:r1126788409">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style><div class="plainlist"> <ul><li><small><abbr class="country-name" title="United States">US</abbr></small> <a href="/wiki/DailyMed" title="DailyMed">DailyMed</a>: <span title="dailymed.nlm.nih.gov"><a rel="nofollow" class="external text" href="https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=Misoprostol">Misoprostol</a></span></li></ul></div> </td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Pregnancy_category" title="Pregnancy category">Pregnancy<br />category</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"> <ul><li><small><abbr class="country-name" title="Australia">AU</abbr>:</small> X (High risk)<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></li> <li><a href="/wiki/Abortifacient" title="Abortifacient">Used for terminating pregnancy</a></li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Route_of_administration" title="Route of administration">Routes of<br />administration</a></th><td class="infobox-data"><a href="/wiki/Oral_administration" title="Oral administration">By mouth</a>, <a href="/wiki/Rectal_administration" title="Rectal administration">rectal</a>, <a href="/wiki/Intravaginal_administration" title="Intravaginal administration">vaginal</a>, <a href="/wiki/Sublingual" class="mw-redirect" title="Sublingual">under the tongue</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Anatomical_Therapeutic_Chemical_Classification_System" title="Anatomical Therapeutic Chemical Classification System">ATC code</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><a href="/wiki/ATC_code_A02" title="ATC code A02">A02BB01</a> (<span title="www.whocc.no"><a rel="nofollow" class="external text" href="https://www.whocc.no/atc_ddd_index/?code=A02BB01">WHO</a></span>) <a href="/wiki/ATC_code_G02" title="ATC code G02">G02AD06</a> (<span title="www.whocc.no"><a rel="nofollow" class="external text" href="https://www.whocc.no/atc_ddd_index/?code=G02AD06">WHO</a></span>)</li></ul></div></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Legal status</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Regulation_of_therapeutic_goods" title="Regulation of therapeutic goods">Legal status</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"> <ul><li><small><abbr class="country-name" title="Australia">AU</abbr>:</small> <a href="/wiki/Standard_for_the_Uniform_Scheduling_of_Medicines_and_Poisons#Schedule_4" title="Standard for the Uniform Scheduling of Medicines and Poisons">S4</a> (Prescription only)<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup></li> <li><small><abbr class="country-name" title="Brazil">BR</abbr>:</small> <a href="/wiki/Brazilian_Controlled_Drugs_and_Substances_Act#Class_C1" title="Brazilian Controlled Drugs and Substances Act">Class C1</a> (Other controlled substances) Hospital use only<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup></li> <li><small><abbr class="country-name" title="Canada">CA</abbr></small>: <a href="/wiki/Prescription_drug" title="Prescription drug"> ℞-only</a></li> <li><small><abbr class="country-name" title="United Kingdom">UK</abbr>:</small> <a href="/wiki/Prescription_drug" title="Prescription drug">POM</a> (Prescription only)<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup></li> <li><small><abbr class="country-name" title="United States">US</abbr>:</small> <a href="/wiki/Boxed_warning" title="Boxed warning"><span style="border:thin solid black;">WARNING</span></a><sup id="cite_ref-FDA-AllBoxedWarnings_3-0" class="reference"><a href="#cite_note-FDA-AllBoxedWarnings-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup>Rx-only<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup></li> <li><small><abbr class="country-name" title="European Union">EU</abbr>:</small> Rx-only<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup></li></ul></div> </td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd"><a href="/wiki/Pharmacokinetics" title="Pharmacokinetics">Pharmacokinetic</a> data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Bioavailability" title="Bioavailability">Bioavailability</a></th><td class="infobox-data">extensively absorbed</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Plasma_protein_binding" title="Plasma protein binding">Protein binding</a></th><td class="infobox-data">80–90% (active metabolite, misoprostol acid)</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Drug_metabolism" title="Drug metabolism">Metabolism</a></th><td class="infobox-data">Liver (extensive to misoprostic acid)</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Biological_half-life" title="Biological half-life">Elimination <span class="nowrap">half-life</span></a></th><td class="infobox-data">20–40 minutes</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Excretion" title="Excretion">Excretion</a></th><td class="infobox-data">Urine (80%)</td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Identifiers</th></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/IUPAC_nomenclature_of_chemistry" title="IUPAC nomenclature of chemistry">IUPAC name</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all; text-align:left; padding-left:1.5em; text-indent:-1.5em;"><li style="line-height: inherit; margin: 0"><div style="font-size: 97%;">Methyl 7-((1<i>R</i>,2<i>R</i>,3<i>R</i>)-3-hydroxy-2-((<i>S,E</i>)-4-hydroxy-4-methyloct-1-enyl)-5-oxocyclopentyl)heptanoate</div></li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/CAS_Registry_Number" title="CAS Registry Number">CAS Number</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="commonchemistry.cas.org"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=59122-46-2">59122-46-2</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/PubChem#CID" title="PubChem">PubChem</a> <span style="font-weight:normal"><abbr title="Compound ID">CID</abbr></span></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="pubchem.ncbi.nlm.nih.gov"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/5282381">5282381</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Guide_to_Pharmacology" title="Guide to Pharmacology">IUPHAR/BPS</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.guidetopharmacology.org"><a rel="nofollow" class="external text" href="https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=1936">1936</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/DrugBank" title="DrugBank">DrugBank</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.drugbank.ca"><a rel="nofollow" class="external text" href="https://www.drugbank.ca/drugs/DB00929">DB00929</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.chemspider.com"><a rel="nofollow" class="external text" href="https://www.chemspider.com/Chemical-Structure.4445541.html">4445541</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Unique_Ingredient_Identifier" title="Unique Ingredient Identifier">UNII</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="precision.fda.gov"><a rel="nofollow" class="external text" href="https://precision.fda.gov/uniisearch/srs/unii/0E43V0BB57">0E43V0BB57</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/KEGG" title="KEGG">KEGG</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.kegg.jp"><a rel="nofollow" class="external text" href="https://www.kegg.jp/entry/D00419">D00419</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChEMBL" title="ChEMBL">ChEMBL</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.ebi.ac.uk"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/ChEMBL606">ChEMBL606</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/CompTox_Chemicals_Dashboard" title="CompTox Chemicals Dashboard">CompTox Dashboard</a> <span style="font-weight:normal">(<abbr title="U.S. Environmental Protection Agency">EPA</abbr>)</span></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="comptox.epa.gov"><a rel="nofollow" class="external text" href="https://comptox.epa.gov/dashboard/chemical/details/DTXSID7020897">DTXSID7020897</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q416025#P3117" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ECHA_InfoCard" class="mw-redirect" title="ECHA InfoCard"><span title="echa.europa.eu">ECHA InfoCard</span></a></th><td class="infobox-data"><a rel="nofollow" class="external text" href="https://echa.europa.eu/substance-information/-/substanceinfo/100.190.521">100.190.521</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q416025#P2566" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Chemical and physical data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Chemical_formula" title="Chemical formula">Formula</a></th><td class="infobox-data"><span title="Carbon">C</span><sub>22</sub><span title="Hydrogen">H</span><sub>38</sub><span title="Oxygen">O</span><sub>5</sub></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Molar_mass" title="Molar mass">Molar mass</a></th><td class="infobox-data"><span class="nowrap"><span data-sort-value="7002382541000000000♠"></span>382.541</span> g·mol<sup>−1</sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;">3D model (<a href="/wiki/JSmol" class="mw-redirect" title="JSmol">JSmol</a>)</th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="chemapps.stolaf.edu (3D interactive model)"><a rel="nofollow" class="external text" href="https://chemapps.stolaf.edu/jmol/jmol.php?model=CCCC%5BC%40%5D%28C%29%28O%29C%2FC%3DC%2F%5BC%40H%5D1%5BC%40H%5D%28O%29CC%28%3DO%29%5BC%40%40H%5D1CCCCCCC%28%3DO%29OC">Interactive image</a></span></li></ul></div></td></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/Simplified_molecular-input_line-entry_system" class="mw-redirect" title="Simplified molecular-input line-entry system">SMILES</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">CCCC[C@](C)(O)C/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)OC</div></li></ul> </div></td></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/International_Chemical_Identifier" title="International Chemical Identifier">InChI</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">InChI=1S/C22H38O5/c1-4-5-14-22(2,26)15-10-12-18-17(19(23)16-20(18)24)11-8-6-7-9-13-21(25)27-3/h10,12,17-18,20,24,26H,4-9,11,13-16H2,1-3H3/b12-10+/t17-,18-,20-,22?/m1/s1<sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></div></li><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">Key:OJLOPKGSLYJEMD-URPKTTJQSA-N<sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></div></li></ul> </div></td></tr><tr><td colspan="2" class="infobox-below"><style data-mw-deduplicate="TemplateStyles:r886047488">.mw-parser-output .nobold{font-weight:normal}</style><span class="nobold">  <span class="reflink plainlinks nourlexpansion"><a class="external text" href="https://en.wikipedia.org/w/index.php?title=Special:ComparePages&rev1=456483721&page2=Misoprostol">(verify)</a></span></span></td></tr></tbody></table> <p><b>Misoprostol</b> is a synthetic <a href="/wiki/Prostaglandin" title="Prostaglandin">prostaglandin</a> medication used to prevent and treat <a href="/wiki/Peptic_ulcer" class="mw-redirect" title="Peptic ulcer">stomach and duodenal ulcers</a>, <a href="/wiki/Labor_induction" title="Labor induction">induce labor</a>, cause an <a href="/wiki/Abortion" title="Abortion">abortion</a>, and treat <a href="/wiki/Postpartum_bleeding" title="Postpartum bleeding">postpartum bleeding</a> due to poor contraction of the <a href="/wiki/Uterus" title="Uterus">uterus</a>.<sup id="cite_ref-Ros2002_10-0" class="reference"><a href="#cite_note-Ros2002-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-AHFS2015_11-0" class="reference"><a href="#cite_note-AHFS2015-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> It is taken <a href="/wiki/By_mouth" class="mw-redirect" title="By mouth">by mouth</a> when used to prevent gastric ulcers in people taking <a href="/wiki/Nonsteroidal_anti-inflammatory_drug" title="Nonsteroidal anti-inflammatory drug">nonsteroidal anti-inflammatory drugs</a> (NSAID).<sup id="cite_ref-AHFS2015_11-1" class="reference"><a href="#cite_note-AHFS2015-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> For abortions it is used by itself or in conjunction with <a href="/wiki/Mifepristone" title="Mifepristone">mifepristone</a> or <a href="/wiki/Methotrexate" title="Methotrexate">methotrexate</a>.<sup id="cite_ref-:3_12-0" class="reference"><a href="#cite_note-:3-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> By itself, effectiveness for abortion is between 66% and 90%.<sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-14" class="reference"><a href="#cite_note-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> For labor induction or abortion, it is taken by mouth, dissolved in the mouth, or <a href="/wiki/Intravaginal_administration" title="Intravaginal administration">placed in the vagina</a>.<sup id="cite_ref-:3_12-1" class="reference"><a href="#cite_note-:3-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-15" class="reference"><a href="#cite_note-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-16" class="reference"><a href="#cite_note-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-ACOG_Practice_Bulletin_No._200:_Ear_17-0" class="reference"><a href="#cite_note-ACOG_Practice_Bulletin_No._200:_Ear-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Early_Pregnancy_Loss_18-0" class="reference"><a href="#cite_note-Early_Pregnancy_Loss-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> For postpartum bleeding it may also be <a href="/wiki/Rectal_administration" title="Rectal administration">used rectally</a>.<sup id="cite_ref-19" class="reference"><a href="#cite_note-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> </p><p>Common side effects include <a href="/wiki/Diarrhea" title="Diarrhea">diarrhea</a> and abdominal pain.<sup id="cite_ref-AHFS2015_11-2" class="reference"><a href="#cite_note-AHFS2015-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> It is in <a href="/wiki/Pregnancy_category" title="Pregnancy category">pregnancy category</a> X, meaning that it is known to result in negative outcomes for the fetus if taken during <a href="/wiki/Pregnancy" title="Pregnancy">pregnancy</a>.<sup id="cite_ref-AHFS2015_11-3" class="reference"><a href="#cite_note-AHFS2015-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> In rare cases, <a href="/wiki/Uterine_rupture" title="Uterine rupture">uterine rupture</a> may occur.<sup id="cite_ref-AHFS2015_11-4" class="reference"><a href="#cite_note-AHFS2015-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> It is a <a href="/wiki/Prostaglandin_analogue" title="Prostaglandin analogue">prostaglandin analogue</a>—specifically, a synthetic <a href="/wiki/Prostaglandin_E1" title="Prostaglandin E1">prostaglandin E<sub>1</sub></a> (PGE<sub>1</sub>).<sup id="cite_ref-AHFS2015_11-5" class="reference"><a href="#cite_note-AHFS2015-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p><p>Misoprostol was developed in 1973.<sup id="cite_ref-20" class="reference"><a href="#cite_note-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup> It is on the <a href="/wiki/WHO_Model_List_of_Essential_Medicines" title="WHO Model List of Essential Medicines">World Health Organization's List of Essential Medicines</a>.<sup id="cite_ref-WHO22nd_21-0" class="reference"><a href="#cite_note-WHO22nd-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup> It is available as a <a href="/wiki/Generic_medication" class="mw-redirect" title="Generic medication">generic medication</a>.<sup id="cite_ref-AHFS2015_11-6" class="reference"><a href="#cite_note-AHFS2015-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Medical_uses">Medical uses</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Misoprostol&action=edit&section=1" title="Edit section: Medical uses"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Ulcer_prevention">Ulcer prevention</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Misoprostol&action=edit&section=2" title="Edit section: Ulcer prevention"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Misoprostol is used for the prevention of <a href="/wiki/NSAID" class="mw-redirect" title="NSAID">NSAID</a>-induced gastric ulcers. It acts upon gastric <a href="/wiki/Parietal_cell" title="Parietal cell">parietal cells</a>, inhibiting the secretion of <a href="/wiki/Gastric_acid" title="Gastric acid">gastric acid</a> by <a href="/wiki/G-protein_coupled_receptor" class="mw-redirect" title="G-protein coupled receptor">G-protein coupled receptor</a>-mediated inhibition of <a href="/wiki/Adenylate_cyclase" class="mw-redirect" title="Adenylate cyclase">adenylate cyclase</a>, which leads to decreased intracellular <a href="/wiki/Cyclic_AMP" class="mw-redirect" title="Cyclic AMP">cyclic AMP</a> levels and decreased <a href="/wiki/Proton_pump" title="Proton pump">proton pump</a> activity at the <a href="/wiki/Apical_membrane" class="mw-redirect" title="Apical membrane">apical</a> surface of the parietal cell. Misoprostol is sometimes coprescribed with NSAIDs to prevent their common adverse effect of <a href="/wiki/Gastric_ulcer" class="mw-redirect" title="Gastric ulcer">gastric ulceration</a> (e.g., with <a href="/wiki/Diclofenac" title="Diclofenac">diclofenac</a> in <i><a href="/wiki/Arthrotec" class="mw-redirect" title="Arthrotec">Arthrotec</a></i>).<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (May 2022)">citation needed</span></a></i>]</sup> </p><p>However, even in the treatment of NSAID-induced ulcers, <a href="/wiki/Omeprazole" title="Omeprazole">omeprazole</a> proved to be at least as effective as misoprostol,<sup id="cite_ref-22" class="reference"><a href="#cite_note-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup> but was significantly better tolerated, so misoprostol should not be considered a first-line treatment. Misoprostol-induced diarrhea and the need for multiple daily doses (typically four) are the main issues impairing compliance with therapy.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Identifying_reliable_sources_(medicine)" title="Wikipedia:Identifying reliable sources (medicine)"><span title="Material near this tag needs references to reliable medical sources. (June 2023)">medical citation needed</span></a></i>]</sup> </p> <div class="mw-heading mw-heading3"><h3 id="Labor_induction">Labor induction</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Misoprostol&action=edit&section=3" title="Edit section: Labor induction"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Misoprostol is commonly used for <a href="/wiki/Labor_induction" title="Labor induction">labor induction</a>. It causes <a href="/wiki/Uterine" class="mw-redirect" title="Uterine">uterine</a> contractions and the ripening (<a href="/wiki/Cervical_effacement" title="Cervical effacement">effacement</a> or thinning) of the <a href="/wiki/Cervix" title="Cervix">cervix</a>.<sup id="cite_ref-23" class="reference"><a href="#cite_note-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup> It can be less expensive than the other commonly used ripening agent, <a href="/wiki/Prostaglandin_E2" title="Prostaglandin E2">dinoprostone</a>.<sup id="cite_ref-summers_24-0" class="reference"><a href="#cite_note-summers-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup> </p><p><a href="/wiki/Oxytocin" title="Oxytocin">Oxytocin</a> has long been used as the standard agent for labor induction, but does not work well when the cervix is not yet ripe. Misoprostol also may be used in conjunction with oxytocin.<sup id="cite_ref-summers_24-1" class="reference"><a href="#cite_note-summers-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup> </p><p>Between 2002 and 2012, a misoprostol vaginal insert was studied, and was approved in the EU.<sup id="cite_ref-25" class="reference"><a href="#cite_note-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-26" class="reference"><a href="#cite_note-26"><span class="cite-bracket">[</span>26<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-27" class="reference"><a href="#cite_note-27"><span class="cite-bracket">[</span>27<span class="cite-bracket">]</span></a></sup> It was not approved for use in the United States, and the US FDA still considers cervical ripening and labor induction to be outside of the approved uses for misoprostol.<sup id="cite_ref-28" class="reference"><a href="#cite_note-28"><span class="cite-bracket">[</span>28<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-29" class="reference"><a href="#cite_note-29"><span class="cite-bracket">[</span>29<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Myomectomy">Myomectomy</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Misoprostol&action=edit&section=4" title="Edit section: Myomectomy"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>When administered prior to <a href="/wiki/Myomectomy" class="mw-redirect" title="Myomectomy">myomectomy</a> in women with uterine fibroids, misoprostol reduces operative blood loss and requirement of blood transfusion.<sup id="cite_ref-30" class="reference"><a href="#cite_note-30"><span class="cite-bracket">[</span>30<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Abortion">Abortion</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Misoprostol&action=edit&section=5" title="Edit section: Abortion"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Misoprostol is used either alone or in conjunction with another medication (<a href="/wiki/Mifepristone" title="Mifepristone">mifepristone</a> or <a href="/wiki/Methotrexate" title="Methotrexate">methotrexate</a>) for <a href="/wiki/Medical_abortion" title="Medical abortion">medical abortions</a> as an alternative to <a href="/wiki/Vacuum_aspiration" title="Vacuum aspiration">surgical abortion</a>.<sup id="cite_ref-31" class="reference"><a href="#cite_note-31"><span class="cite-bracket">[</span>31<span class="cite-bracket">]</span></a></sup> Medical abortion has the advantage of being less invasive, and more autonomous, self-directed, and discreet. It is preferred by some women because it feels more natural, as the drugs induce a miscarriage.<sup id="cite_ref-32" class="reference"><a href="#cite_note-32"><span class="cite-bracket">[</span>32<span class="cite-bracket">]</span></a></sup> It is also more easily accessible in places where abortion is illegal.<sup id="cite_ref-33" class="reference"><a href="#cite_note-33"><span class="cite-bracket">[</span>33<span class="cite-bracket">]</span></a></sup> The <a href="/wiki/World_Health_Organization" title="World Health Organization">World Health Organization</a> (WHO) provides clear guidelines on the use, benefits and risks of misoprostol for abortions.<sup id="cite_ref-34" class="reference"><a href="#cite_note-34"><span class="cite-bracket">[</span>34<span class="cite-bracket">]</span></a></sup> </p><p>Misoprostol is most effective when it is used in combination with methotrexate or mifepristone (RU-486).<sup id="cite_ref-:0_35-0" class="reference"><a href="#cite_note-:0-35"><span class="cite-bracket">[</span>35<span class="cite-bracket">]</span></a></sup> Mifepristone blocks signaling by <a href="/wiki/Progesterone" title="Progesterone">progesterone</a>, causing the uterine lining to degrade, the blood vessels of the <a href="/wiki/Cervix" title="Cervix">cervix</a> and <a href="/wiki/Uterus" title="Uterus">uterus</a> to dilate and causing uterine contraction, similar to a <a href="/wiki/Menstrual_period" class="mw-redirect" title="Menstrual period">menstrual period</a>, which causes the embryo to detach from the uterine walls.<sup id="cite_ref-AHFS2023_36-0" class="reference"><a href="#cite_note-AHFS2023-36"><span class="cite-bracket">[</span>36<span class="cite-bracket">]</span></a></sup> Misoprostol then dilates the cervix and induces muscle contractions which clear the uterus.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (March 2021)">citation needed</span></a></i>]</sup> Misoprostol alone is less effective (typically 88% up to eight-weeks gestation). It is not inherently unsafe if medically supervised, but 1% of women will have heavy bleeding requiring medical attention, some women may have <a href="/wiki/Ectopic_pregnancy" title="Ectopic pregnancy">ectopic pregnancy</a>, and the 12% of pregnancies that continue after misoprostol failure are more likely to have birth defects and are usually followed up with a more effective method of abortion.<sup id="cite_ref-Gunter_37-0" class="reference"><a href="#cite_note-Gunter-37"><span class="cite-bracket">[</span>37<span class="cite-bracket">]</span></a></sup> </p><p>Most large studies recommend a protocol for the use of misoprostol in combination with mifepristone.<sup id="cite_ref-38" class="reference"><a href="#cite_note-38"><span class="cite-bracket">[</span>38<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-39" class="reference"><a href="#cite_note-39"><span class="cite-bracket">[</span>39<span class="cite-bracket">]</span></a></sup> Together they are effective in around 95% for early pregnancies.<sup id="cite_ref-40" class="reference"><a href="#cite_note-40"><span class="cite-bracket">[</span>40<span class="cite-bracket">]</span></a></sup> Misoprostol alone may be more effective in earlier gestation.<sup id="cite_ref-41" class="reference"><a href="#cite_note-41"><span class="cite-bracket">[</span>41<span class="cite-bracket">]</span></a></sup> </p><p>Misoprostol can also be used to <a href="/wiki/Cervical_dilation" title="Cervical dilation">dilate the cervix</a> in preparation for a surgical abortion, particularly in the second trimester (either alone or in combination with <a href="/wiki/Osmotic_dilators" class="mw-redirect" title="Osmotic dilators">osmotic dilators</a>). Vaginal misoprostol can also be used to facilitate <a href="/wiki/Intrauterine_device" title="Intrauterine device">intrauterine device</a> insertion after previous insertion failure.<sup id="cite_ref-42" class="reference"><a href="#cite_note-42"><span class="cite-bracket">[</span>42<span class="cite-bracket">]</span></a></sup> </p><p>Misoprostol by mouth is the least effective treatment for producing complete abortion in a period of 24 hours due to the liver's <a href="/wiki/First_pass_effect" title="First pass effect">first-pass effect</a> which reduces the <a href="/wiki/Bioavailability" title="Bioavailability">bioavailability</a> of the misoprostol. Vaginal and sublingual routes result in greater efficacy and extended duration of action because these routes of administration allow the drug to be directly absorbed into circulation by bypassing the liver first-pass effect.<sup id="cite_ref-:1_43-0" class="reference"><a href="#cite_note-:1-43"><span class="cite-bracket">[</span>43<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-ACOG_Practice_Bulletin_No._200:_Ear_17-1" class="reference"><a href="#cite_note-ACOG_Practice_Bulletin_No._200:_Ear-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Early_Pregnancy_Loss_18-1" class="reference"><a href="#cite_note-Early_Pregnancy_Loss-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> </p><p><a href="/wiki/Hematocrit" title="Hematocrit">Hematocrit</a> or Hb tests and Rh testing are recommended before use for abortion confirmation of pregnancy.<sup id="cite_ref-:2_44-0" class="reference"><a href="#cite_note-:2-44"><span class="cite-bracket">[</span>44<span class="cite-bracket">]</span></a></sup> Following use, it is recommended that people attend a follow-up visit 2 weeks after treatment. If used for treatment of complete abortion, a pregnancy test, physical examination of the uterus, and ultrasound should be performed to ensure success of treatment. Surgical management is possible in the case of failed treatment.<sup id="cite_ref-:1_43-1" class="reference"><a href="#cite_note-:1-43"><span class="cite-bracket">[</span>43<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Early_pregnancy_loss">Early pregnancy loss</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Misoprostol&action=edit&section=6" title="Edit section: Early pregnancy loss"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Misoprostol may be used to complete a <a href="/wiki/Miscarriage" title="Miscarriage">miscarriage</a> or <a href="/wiki/Missed_abortion" class="mw-redirect" title="Missed abortion">missed abortion</a> when the body does not expel the embryo or fetus on its own. Compared to no medication or placebo, it could decrease the time to complete expulsion.<sup id="cite_ref-45" class="reference"><a href="#cite_note-45"><span class="cite-bracket">[</span>45<span class="cite-bracket">]</span></a></sup> Use of a single dose of misoprostol vaginally or buccally is preferred, with additional doses as needed. It also can be used in combination with mifepristone, with a similar regimen to medical abortion.<sup id="cite_ref-ACOG_Practice_Bulletin_No._200:_Ear_17-2" class="reference"><a href="#cite_note-ACOG_Practice_Bulletin_No._200:_Ear-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Early_Pregnancy_Loss_18-2" class="reference"><a href="#cite_note-Early_Pregnancy_Loss-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> </p><p>Misoprostol is regularly used in some Canadian hospitals for labour induction for fetal deaths early in pregnancy, and for termination of pregnancy for fetal anomalies. A low dose is used initially, then doubled for the remaining doses until delivery. In the case of a previous Caesarian section, however, lower doses are used. </p> <div class="mw-heading mw-heading3"><h3 id="Postpartum_bleeding">Postpartum bleeding</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Misoprostol&action=edit&section=7" title="Edit section: Postpartum bleeding"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Misoprostol is also used to prevent and treat <a href="/wiki/Post-partum_bleeding" class="mw-redirect" title="Post-partum bleeding">post-partum bleeding</a>. Orally administered misoprostol was marginally less effective than <a href="/wiki/Oxytocin" title="Oxytocin">oxytocin</a>.<sup id="cite_ref-46" class="reference"><a href="#cite_note-46"><span class="cite-bracket">[</span>46<span class="cite-bracket">]</span></a></sup> The use of rectally administered misoprostol is optimal in cases of bleeding; it was shown to be associated with lower rates of side effects compared to other routes. Rectally administered misoprostol was reported in a variety of case reports and randomised controlled trials.<sup id="cite_ref-47" class="reference"><a href="#cite_note-47"><span class="cite-bracket">[</span>47<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-48" class="reference"><a href="#cite_note-48"><span class="cite-bracket">[</span>48<span class="cite-bracket">]</span></a></sup> However, it is inexpensive and thermostable (thus does not require refrigeration like oxytocin), making it a cost-effective and valuable drug to use in the developing world.<sup id="cite_ref-49" class="reference"><a href="#cite_note-49"><span class="cite-bracket">[</span>49<span class="cite-bracket">]</span></a></sup> A randomised control trial of misoprostol use found a 38% reduction in maternal deaths due to <i>post partum</i> haemorrhage in resource-poor communities.<sup id="cite_ref-50" class="reference"><a href="#cite_note-50"><span class="cite-bracket">[</span>50<span class="cite-bracket">]</span></a></sup> Misoprostol is recommended due to its cost, effectiveness, stability, and low rate of side effects.<sup id="cite_ref-51" class="reference"><a href="#cite_note-51"><span class="cite-bracket">[</span>51<span class="cite-bracket">]</span></a></sup> Oxytocin must also be given by injection, while misprostol can be given orally or rectally for this use, making it much more useful in areas where nurses and physicians are less available.<sup id="cite_ref-52" class="reference"><a href="#cite_note-52"><span class="cite-bracket">[</span>52<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Insertion_of_intrauterine_contraceptive_device">Insertion of intrauterine contraceptive device</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Misoprostol&action=edit&section=8" title="Edit section: Insertion of intrauterine contraceptive device"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>In women with prior caesarean section or prior failure of insertion of an intrauterine contraceptive device, pre-procedure administration of misoprostol reduces the rate of failure of insertion of intrauterine contraceptive device. However, due to a higher rate of adverse effects, routine use of misoprostol for this purpose in other women is not supported by the data.<sup id="cite_ref-53" class="reference"><a href="#cite_note-53"><span class="cite-bracket">[</span>53<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Other">Other</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Misoprostol&action=edit&section=9" title="Edit section: Other"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>For <a href="/wiki/Cervical_dilation" title="Cervical dilation">cervical ripening</a> in advance of endometrial biopsy to reduce the need for use of a tenaculum or cervical dilator.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (May 2022)">citation needed</span></a></i>]</sup> </p><p>There is limited evidence supporting the use of misoprostol for the treatment of <a href="/wiki/Trigeminal_neuralgia" title="Trigeminal neuralgia">trigeminal neuralgia</a> in patients with <a href="/wiki/Multiple_sclerosis" title="Multiple sclerosis">multiple sclerosis</a>.<sup id="cite_ref-54" class="reference"><a href="#cite_note-54"><span class="cite-bracket">[</span>54<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-55" class="reference"><a href="#cite_note-55"><span class="cite-bracket">[</span>55<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Adverse_effects">Adverse effects</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Misoprostol&action=edit&section=10" title="Edit section: Adverse effects"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The most commonly reported <a href="/wiki/Adverse_effect" title="Adverse effect">adverse effect</a> of taking misoprostol by mouth for the prevention of stomach ulcers is <a href="/wiki/Diarrhea" title="Diarrhea">diarrhea</a>. In clinical trials, an average 13% of people reported diarrhea, which was dose-related and usually developed early in the course of therapy (after 13 days) and was usually self-limiting (often resolving within 8 days), but sometimes (in 2% of people) required discontinuation of misoprostol.<sup id="cite_ref-Cytotec_USPI_56-0" class="reference"><a href="#cite_note-Cytotec_USPI-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup> </p><p>The next most commonly reported adverse effects of taking misoprostol by mouth for the prevention of gastric ulcers are: <a href="/wiki/Abdominal_pain" title="Abdominal pain">abdominal pain</a>, <a href="/wiki/Nausea" title="Nausea">nausea</a>, <a href="/wiki/Flatulence" title="Flatulence">flatulence</a>, <a href="/wiki/Headache" title="Headache">headache</a>, <a href="/wiki/Dyspepsia" class="mw-redirect" title="Dyspepsia">dyspepsia</a>, <a href="/wiki/Vomiting" title="Vomiting">vomiting</a>, and <a href="/wiki/Constipation" title="Constipation">constipation</a>, but none of these adverse effects occurred more often than when taking <a href="/wiki/Placebo" title="Placebo">placebos</a>.<sup id="cite_ref-Cytotec_USPI_56-1" class="reference"><a href="#cite_note-Cytotec_USPI-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup> </p><p>There are increased side effects with sublingual or oral misoprostol, compared to a low dose (400 μg) vaginal misoprostol. However, low dose vaginal misoprostol was linked with low complete abortion rate.<sup id="cite_ref-:1_43-2" class="reference"><a href="#cite_note-:1-43"><span class="cite-bracket">[</span>43<span class="cite-bracket">]</span></a></sup> The study concluded that sublingually administered misoprostol dosed at 600 μg or 400 μg had greater instances of fever and diarrhea due to its quicker onset of action, higher peak concentration and bioavailability in comparison to vaginal or oral misoprostol.<sup id="cite_ref-:1_43-3" class="reference"><a href="#cite_note-:1-43"><span class="cite-bracket">[</span>43<span class="cite-bracket">]</span></a></sup> </p><p>For the indication of medical abortion, bleeding and cramping is commonly experienced after administration of misoprostol. Bleeding and cramping is likely to be greater than that experienced with menses, however, emergency care is advised if bleeding is excessive.<sup id="cite_ref-:2_44-1" class="reference"><a href="#cite_note-:2-44"><span class="cite-bracket">[</span>44<span class="cite-bracket">]</span></a></sup> </p><p>Misoprostol should not be taken by pregnant women with wanted pregnancies to reduce the risk of NSAID-induced gastric ulcers because it increases uterine tone and contractions in pregnancy, which may cause partial or complete abortions, and because its use in pregnancy has been associated with birth defects.<sup id="cite_ref-Cytotec_USPI_56-2" class="reference"><a href="#cite_note-Cytotec_USPI-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Cytotec_UK_SPC_57-0" class="reference"><a href="#cite_note-Cytotec_UK_SPC-57"><span class="cite-bracket">[</span>57<span class="cite-bracket">]</span></a></sup> </p><p>All cervical ripening and induction agents can cause <a href="/wiki/Uterine_hyperstimulation" title="Uterine hyperstimulation">uterine hyperstimulation</a>, which can negatively affect the blood supply to the fetus and increases the risk of complications such as uterine rupture.<sup id="cite_ref-briggs_58-0" class="reference"><a href="#cite_note-briggs-58"><span class="cite-bracket">[</span>58<span class="cite-bracket">]</span></a></sup> Concern has been raised that uterine hyperstimulation that occurs during a misoprostol-induced labor is more difficult to treat than hyperstimulation during labors induced by other drugs.<sup id="cite_ref-59" class="reference"><a href="#cite_note-59"><span class="cite-bracket">[</span>59<span class="cite-bracket">]</span></a></sup> Because the complications are rare, it is difficult to determine if misoprostol causes a higher risk than do other cervical ripening agents. One estimate is that it would require around 61,000 people enrolled in randomized controlled trials to detect a difference in serious fetal complications and about 155,000 people to detect a difference in serious maternal complications.<sup id="cite_ref-60" class="reference"><a href="#cite_note-60"><span class="cite-bracket">[</span>60<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Contraindications">Contraindications</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Misoprostol&action=edit&section=11" title="Edit section: Contraindications"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>It is recommended that medical treatment for <a href="/wiki/Missed_abortion" class="mw-redirect" title="Missed abortion">missed abortion</a> with misoprostol should only be considered in people without the following contraindications: suspected ectopic pregnancy, use of non-steroidal drugs, signs of pelvic infections or sepsis, unstable hemodynamics, known allergy to misoprostol, previous caesarean section, mitral stenosis, hypertension, glaucoma, bronchial asthma, and remote areas without a hospital nearby.<sup id="cite_ref-:1_43-4" class="reference"><a href="#cite_note-:1-43"><span class="cite-bracket">[</span>43<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Pharmacology">Pharmacology</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Misoprostol&action=edit&section=12" title="Edit section: Pharmacology"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Mechanism_of_action">Mechanism of action</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Misoprostol&action=edit&section=13" title="Edit section: Mechanism of action"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Misoprostol, a <a href="/wiki/Prostaglandin_analogue" title="Prostaglandin analogue">prostaglandin analogue</a>, binds to myometrial cells to cause strong myometrial contractions leading to expulsion of tissue. This agent also causes cervical ripening with softening and dilation of the cervix. Misoprostol binds to and stimulates <a href="/wiki/Prostaglandin_EP2_receptor" title="Prostaglandin EP2 receptor">prostaglandin EP<sub>2</sub> receptors</a>, <a href="/wiki/Prostaglandin_EP3_receptor" title="Prostaglandin EP3 receptor">prostaglandin EP<sub>3</sub> receptor</a> and <a href="/wiki/Prostaglandin_EP4_receptor" title="Prostaglandin EP4 receptor">prostaglandin EP<sub>4</sub> receptor</a> but not <a href="/wiki/Prostaglandin_EP1_receptor" title="Prostaglandin EP1 receptor">prostaglandin EP<sub>1</sub> receptor</a> and therefore is expected to have a more restricted range of physiological and potentially toxic actions than prostaglandin E<sub>2</sub> or other analogs which activate all four prostaglandin receptors.<sup id="cite_ref-pmid27940058_61-0" class="reference"><a href="#cite_note-pmid27940058-61"><span class="cite-bracket">[</span>61<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Society_and_culture">Society and culture</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Misoprostol&action=edit&section=14" title="Edit section: Society and culture"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>In August 2000, a letter from <a href="/wiki/G.D._Searle,_LLC" title="G.D. Searle, LLC">G.D. Searle, LLC</a>, the inventor of the drug,<sup id="cite_ref-62" class="reference"><a href="#cite_note-62"><span class="cite-bracket">[</span>62<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-63" class="reference"><a href="#cite_note-63"><span class="cite-bracket">[</span>63<span class="cite-bracket">]</span></a></sup> generated controversy by warning against its use by pregnant women because of its ability to induce abortion, citing reports of maternal and fetal deaths when it was used to induce labor.<sup id="cite_ref-goldberg_64-0" class="reference"><a href="#cite_note-goldberg-64"><span class="cite-bracket">[</span>64<span class="cite-bracket">]</span></a></sup> The <a href="/wiki/American_College_of_Obstetricians_and_Gynecologists" title="American College of Obstetricians and Gynecologists">American College of Obstetricians and Gynecologists</a> holds that substantial evidence supports the use of misoprostol for induction of labor, a position it reaffirmed in response to the Searle letter.<sup id="cite_ref-65" class="reference"><a href="#cite_note-65"><span class="cite-bracket">[</span>65<span class="cite-bracket">]</span></a></sup> It is on the <a href="/wiki/WHO_Model_List_of_Essential_Medicines" title="WHO Model List of Essential Medicines">World Health Organization's List of Essential Medicines</a>.<sup id="cite_ref-WHO22nd_21-1" class="reference"><a href="#cite_note-WHO22nd-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup> </p><p>A vaginal form of the medication is sold in the EU under the names Misodel<sup id="cite_ref-66" class="reference"><a href="#cite_note-66"><span class="cite-bracket">[</span>66<span class="cite-bracket">]</span></a></sup> and Mysodelle<sup id="cite_ref-67" class="reference"><a href="#cite_note-67"><span class="cite-bracket">[</span>67<span class="cite-bracket">]</span></a></sup> for use in labor induction.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Identifying_reliable_sources_(medicine)" title="Wikipedia:Identifying reliable sources (medicine)"><span title="Material near this tag needs references to reliable medical sources. (February 2020)">medical citation needed</span></a></i>]</sup> </p> <div class="mw-heading mw-heading3"><h3 id="Black_market">Black market</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Misoprostol&action=edit&section=15" title="Edit section: Black market"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Misoprostol is used for <a href="/wiki/Self-induced_abortion" title="Self-induced abortion">self-induced abortions</a> in Brazil, where <a href="/wiki/Black_market" title="Black market">black market</a> prices exceed US$100 per dose. Illegal medically unsupervised misoprostol abortions in Brazil are associated with a lower complication rate than other forms of illegal self-induced abortion, but are still associated with a higher complication rate than legal, medically supervised surgical and medical abortions. Failed misoprostol abortions are associated with birth defects in some cases.<sup id="cite_ref-68" class="reference"><a href="#cite_note-68"><span class="cite-bracket">[</span>68<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-69" class="reference"><a href="#cite_note-69"><span class="cite-bracket">[</span>69<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-70" class="reference"><a href="#cite_note-70"><span class="cite-bracket">[</span>70<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-71" class="reference"><a href="#cite_note-71"><span class="cite-bracket">[</span>71<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-72" class="reference"><a href="#cite_note-72"><span class="cite-bracket">[</span>72<span class="cite-bracket">]</span></a></sup> Low-income and immigrant populations in <a href="/wiki/New_York_City" title="New York City">New York City</a> have also been observed to use self-administered misoprostol to induce abortions, as this method is much cheaper than a surgical abortion (about $2 per dose).<sup id="cite_ref-73" class="reference"><a href="#cite_note-73"><span class="cite-bracket">[</span>73<span class="cite-bracket">]</span></a></sup> The drug is readily available in Mexico.<sup id="cite_ref-NYT71313_74-0" class="reference"><a href="#cite_note-NYT71313-74"><span class="cite-bracket">[</span>74<span class="cite-bracket">]</span></a></sup> Use of misoprostol has also increased in Texas in response to increased regulation of abortion providers.<sup id="cite_ref-75" class="reference"><a href="#cite_note-75"><span class="cite-bracket">[</span>75<span class="cite-bracket">]</span></a></sup> Following the United States Supreme Court decision of <a href="/wiki/Dobbs_v._Jackson_Women%27s_Health_Organization" title="Dobbs v. Jackson Women's Health Organization">Dobbs v. Jackson Women's Health Organization</a>, many states restricted access to legal abortion services, including medication abortion using misoprostol. As a result of these restrictions, it was reported that there was an increase in self-managed abortions by women in the United States. Many women purchased the pills from overseas online pharmacies or obtained misoprostol from Mexico.<sup id="cite_ref-76" class="reference"><a href="#cite_note-76"><span class="cite-bracket">[</span>76<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Misoprostol&action=edit&section=16" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2023-PI-01073-1">"TGA eBS - Product and Consumer Medicine Information Licence"</a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20230414033450/https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2023-PI-01073-1">Archived</a> from the original on 14 April 2023<span class="reference-accessdate">. Retrieved <span class="nowrap">14 April</span> 2023</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=TGA+eBS+-+Product+and+Consumer+Medicine+Information+Licence&rft_id=https%3A%2F%2Fwww.ebs.tga.gov.au%2Febs%2Fpicmi%2Fpicmirepository.nsf%2Fpdf%3FOpenAgent%26id%3DCP-2023-PI-01073-1&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2010-PI-05416-3">"TGA eBS - Product and Consumer Medicine Information Licence"</a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20230414031955/https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2010-PI-05416-3">Archived</a> from the original on 14 April 2023<span class="reference-accessdate">. Retrieved <span class="nowrap">14 April</span> 2023</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=TGA+eBS+-+Product+and+Consumer+Medicine+Information+Licence&rft_id=https%3A%2F%2Fwww.ebs.tga.gov.au%2Febs%2Fpicmi%2Fpicmirepository.nsf%2Fpdf%3FOpenAgent%26id%3DCP-2010-PI-05416-3&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span></span> </li> <li id="cite_note-FDA-AllBoxedWarnings-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-FDA-AllBoxedWarnings_3-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802">"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)"</a>. <i>nctr-crs.fda.gov</i>. <a href="/wiki/FDA" class="mw-redirect" title="FDA">FDA</a><span class="reference-accessdate">. Retrieved <span class="nowrap">22 October</span> 2023</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=nctr-crs.fda.gov&rft.atitle=FDA-sourced+list+of+all+drugs+with+black+box+warnings+%28Use+Download+Full+Results+and+View+Query+links.%29&rft_id=https%3A%2F%2Fnctr-crs.fda.gov%2Ffdalabel%2Fui%2Fspl-summaries%2Fcriteria%2F343802&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.tga.gov.au/resources/prescription-medicines-registrations/angusta-norgine-pty-ltd">"Angusta (Norgine Pty Ltd)"</a>. <i>Therapeutic Goods Administration (TGA)</i>. 13 January 2023. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20230318025815/https://www.tga.gov.au/resources/prescription-medicines-registrations/angusta-norgine-pty-ltd">Archived</a> from the original on 18 March 2023<span class="reference-accessdate">. Retrieved <span class="nowrap">9 April</span> 2023</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Therapeutic+Goods+Administration+%28TGA%29&rft.atitle=Angusta+%28Norgine+Pty+Ltd%29&rft.date=2023-01-13&rft_id=https%3A%2F%2Fwww.tga.gov.au%2Fresources%2Fprescription-medicines-registrations%2Fangusta-norgine-pty-ltd&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-5">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAnvisa2023" class="citation web cs1 cs1-prop-foreign-lang-source"><a href="/wiki/Brazilian_Health_Regulatory_Agency" title="Brazilian Health Regulatory Agency">Anvisa</a> (31 March 2023). <a rel="nofollow" class="external text" href="https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992">"RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial"</a> [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). <a href="/wiki/Di%C3%A1rio_Oficial_da_Uni%C3%A3o" title="Diário Oficial da União">Diário Oficial da União</a> (published 4 April 2023). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20230803143925/https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992">Archived</a> from the original on 3 August 2023<span class="reference-accessdate">. Retrieved <span class="nowrap">15 August</span> 2023</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=RDC+N%C2%BA+784+-+Listas+de+Subst%C3%A2ncias+Entorpecentes%2C+Psicotr%C3%B3picas%2C+Precursoras+e+Outras+sob+Controle+Especial&rft.pub=Di%C3%A1rio+Oficial+da+Uni%C3%A3o&rft.date=2023-03-31&rft.au=Anvisa&rft_id=https%3A%2F%2Fwww.in.gov.br%2Fen%2Fweb%2Fdou%2F-%2Fresolucao-rdc-n-784-de-31-de-marco-de-2023-474904992&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-6">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.medicines.org.uk/emc/product/12147/smpc">"Angusta 25 microgram tablets - Summary of Product Characteristics (SmPC)"</a>. <i>(emc)</i>. 8 April 2022. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20230410051926/https://www.medicines.org.uk/emc/product/12147/smpc">Archived</a> from the original on 10 April 2023<span class="reference-accessdate">. Retrieved <span class="nowrap">9 April</span> 2023</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=%28emc%29&rft.atitle=Angusta+25+microgram+tablets+-+Summary+of+Product+Characteristics+%28SmPC%29&rft.date=2022-04-08&rft_id=https%3A%2F%2Fwww.medicines.org.uk%2Femc%2Fproduct%2F12147%2Fsmpc&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span></span> </li> <li id="cite_note-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-7">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4ab12da7-5731-4e06-bf1c-bc3f2e711f12">"Cytotec- misoprostol tablet"</a>. <i>DailyMed</i>. 9 July 2021. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20230418121539/https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4ab12da7-5731-4e06-bf1c-bc3f2e711f12">Archived</a> from the original on 18 April 2023<span class="reference-accessdate">. Retrieved <span class="nowrap">13 April</span> 2023</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=DailyMed&rft.atitle=Cytotec-+misoprostol+tablet&rft.date=2021-07-09&rft_id=https%3A%2F%2Fdailymed.nlm.nih.gov%2Fdailymed%2FdrugInfo.cfm%3Fsetid%3D4ab12da7-5731-4e06-bf1c-bc3f2e711f12&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span></span> </li> <li id="cite_note-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-8">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ema.europa.eu/documents/psusa/misoprostol-gynaecological-indication-labour-induction-list-nationally-authorised-medicinal-products/00010353/202005_en.pdf">"List of nationally authorised medicinal products. Misoprostol (gastrointestinal indication). Procedure no.: PSUSA/00010353/202005"</a> <span class="cs1-format">(PDF)</span>. European Medicines Agency. 14 January 2021. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20220629032409/https://www.ema.europa.eu/en/documents/psusa/misoprostol-gynaecological-indication-labour-induction-list-nationally-authorised-medicinal-products/00010353/202005_en.pdf">Archived</a> <span class="cs1-format">(PDF)</span> from the original on 29 June 2022<span class="reference-accessdate">. Retrieved <span class="nowrap">8 August</span> 2021</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=List+of+nationally+authorised+medicinal+products.+Misoprostol+%28gastrointestinal+indication%29.+Procedure+no.%3A+PSUSA%2F00010353%2F202005&rft.pub=European+Medicines+Agency&rft.date=2021-01-14&rft_id=https%3A%2F%2Fwww.ema.europa.eu%2Fdocuments%2Fpsusa%2Fmisoprostol-gynaecological-indication-labour-induction-list-nationally-authorised-medicinal-products%2F00010353%2F202005_en.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span></span> </li> <li id="cite_note-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-9">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ema.europa.eu/documents/psusa/misoprostol-gastrointestinal-indication-list-nationally-authorised-medicinal-products-psusa/00010291/202006_en.pdf">"List of nationally authorised medicinal products. 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If this is an intentional citation to a retracted paper, please replace <code>{{<a href="/wiki/Template:Retracted" title="Template:Retracted">retracted</a>|...}}</code> with <code>{{<a href="/wiki/Template:Retracted" title="Template:Retracted">retracted</a>|...|intentional=yes}}</code>.</span>)</span></span> </li> <li id="cite_note-:1-43"><span class="mw-cite-backlink">^ <a href="#cite_ref-:1_43-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-:1_43-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-:1_43-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-:1_43-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-:1_43-4"><sup><i><b>e</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFWuMarwahWangWang2017" class="citation journal cs1">Wu HL, Marwah S, Wang P, Wang QM, Chen XW (May 2017). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431938">"Misoprostol for medical treatment of missed abortion: a systematic review and network meta-analysis"</a>. <i>Scientific Reports</i>. <b>7</b> (1): 1664. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2017NatSR...7.1664W">2017NatSR...7.1664W</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fs41598-017-01892-0">10.1038/s41598-017-01892-0</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431938">5431938</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/28490770">28490770</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Scientific+Reports&rft.atitle=Misoprostol+for+medical+treatment+of+missed+abortion%3A+a+systematic+review+and+network+meta-analysis&rft.volume=7&rft.issue=1&rft.pages=1664&rft.date=2017-05&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC5431938%23id-name%3DPMC&rft_id=info%3Apmid%2F28490770&rft_id=info%3Adoi%2F10.1038%2Fs41598-017-01892-0&rft_id=info%3Abibcode%2F2017NatSR...7.1664W&rft.aulast=Wu&rft.aufirst=HL&rft.au=Marwah%2C+S&rft.au=Wang%2C+P&rft.au=Wang%2C+QM&rft.au=Chen%2C+XW&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC5431938&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span> <span typeof="mw:File"><a href="/wiki/File:CC_BY_icon.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e1/CC_BY_icon.svg/50px-CC_BY_icon.svg.png" decoding="async" width="50" height="18" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e1/CC_BY_icon.svg/75px-CC_BY_icon.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e1/CC_BY_icon.svg/100px-CC_BY_icon.svg.png 2x" data-file-width="88" data-file-height="31" /></a></span> Material was copied from this source, which is available under a <a rel="nofollow" class="external text" href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20171016050101/https://creativecommons.org/licenses/by/4.0/">Archived</a> 16 October 2017 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a>.</span> </li> <li id="cite_note-:2-44"><span class="mw-cite-backlink">^ <a href="#cite_ref-:2_44-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-:2_44-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAmerican_College_of_Obstetricians_Gynecologists2014" class="citation journal cs1">American College of Obstetricians Gynecologists (March 2014). 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"Oral misoprostol administration for labor induction". <i>Clinical Obstetrics and Gynecology</i>. <b>49</b> (3): 658–71. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1097%2F00003081-200609000-00023">10.1097/00003081-200609000-00023</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16885670">16885670</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:13063131">13063131</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Clinical+Obstetrics+and+Gynecology&rft.atitle=Oral+misoprostol+administration+for+labor+induction&rft.volume=49&rft.issue=3&rft.pages=658-71&rft.date=2006-09&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A13063131%23id-name%3DS2CID&rft_id=info%3Apmid%2F16885670&rft_id=info%3Adoi%2F10.1097%2F00003081-200609000-00023&rft.aulast=Weeks&rft.aufirst=A&rft.au=Alfirevic%2C+Z&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span></dd></dl> </span></li> <li id="cite_note-pmid27940058-61"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid27940058_61-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMoreno2017" class="citation journal cs1">Moreno JJ (February 2017). "Eicosanoid receptors: Targets for the treatment of disrupted intestinal epithelial homeostasis". <i>European Journal of Pharmacology</i>. <b>796</b>: 7–19. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.ejphar.2016.12.004">10.1016/j.ejphar.2016.12.004</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/27940058">27940058</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:1513449">1513449</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=European+Journal+of+Pharmacology&rft.atitle=Eicosanoid+receptors%3A+Targets+for+the+treatment+of+disrupted+intestinal+epithelial+homeostasis&rft.volume=796&rft.pages=7-19&rft.date=2017-02&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A1513449%23id-name%3DS2CID&rft_id=info%3Apmid%2F27940058&rft_id=info%3Adoi%2F10.1016%2Fj.ejphar.2016.12.004&rft.aulast=Moreno&rft.aufirst=JJ&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span></span> </li> <li id="cite_note-62"><span class="mw-cite-backlink"><b><a href="#cite_ref-62">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFTyman1999" class="citation book cs1">Tyman JH (January 1999). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=1A6kAgAAQBAJ&dq=%22inventor+of+misoprostol%22&pg=PA125"><i>Lipids in Health and Nutrition</i></a>. Elsevier. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/9781845698386" title="Special:BookSources/9781845698386"><bdi>9781845698386</bdi></a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20220629032411/https://books.google.com/books?id=1A6kAgAAQBAJ&dq=%22inventor+of+misoprostol%22&pg=PA125">Archived</a> from the original on 29 June 2022<span class="reference-accessdate">. Retrieved <span class="nowrap">10 May</span> 2022</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Lipids+in+Health+and+Nutrition&rft.pub=Elsevier&rft.date=1999-01&rft.isbn=9781845698386&rft.aulast=Tyman&rft.aufirst=JH&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3D1A6kAgAAQBAJ%26dq%3D%2522inventor%2Bof%2Bmisoprostol%2522%26pg%3DPA125&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span></span> </li> <li id="cite_note-63"><span class="mw-cite-backlink"><b><a href="#cite_ref-63">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFFeatherstone2016" class="citation book cs1">Featherstone L (June 2016). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=Fm7nDwAAQBAJ&dq=%22misoprostol%22+%22searle%22+%22Rumsfeld%22&pg=PT129"><i>False Choices: The Faux Feminism of Hillary Rodham Clinton</i></a>. Verso Books. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/9781784784638" title="Special:BookSources/9781784784638"><bdi>9781784784638</bdi></a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20220629032412/https://books.google.com/books?id=Fm7nDwAAQBAJ&dq=%22misoprostol%22+%22searle%22+%22Rumsfeld%22&pg=PT129">Archived</a> from the original on 29 June 2022<span class="reference-accessdate">. Retrieved <span class="nowrap">10 May</span> 2022</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=False+Choices%3A+The+Faux+Feminism+of+Hillary+Rodham+Clinton&rft.pub=Verso+Books&rft.date=2016-06&rft.isbn=9781784784638&rft.aulast=Featherstone&rft.aufirst=L&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DFm7nDwAAQBAJ%26dq%3D%2522misoprostol%2522%2B%2522searle%2522%2B%2522Rumsfeld%2522%26pg%3DPT129&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span></span> </li> <li id="cite_note-goldberg-64"><span class="mw-cite-backlink"><b><a href="#cite_ref-goldberg_64-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGoldbergWing2003" class="citation journal cs1">Goldberg AB, Wing DA (2003). "Induction of labor: the misoprostol controversy". <i>Journal of Midwifery & Women's Health</i>. <b>48</b> (4): 244–8. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS1526-9523%2803%2900087-4">10.1016/S1526-9523(03)00087-4</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12867908">12867908</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Midwifery+%26+Women%27s+Health&rft.atitle=Induction+of+labor%3A+the+misoprostol+controversy&rft.volume=48&rft.issue=4&rft.pages=244-8&rft.date=2003&rft_id=info%3Adoi%2F10.1016%2FS1526-9523%2803%2900087-4&rft_id=info%3Apmid%2F12867908&rft.aulast=Goldberg&rft.aufirst=AB&rft.au=Wing%2C+DA&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span></span> </li> <li id="cite_note-65"><span class="mw-cite-backlink"><b><a href="#cite_ref-65">^</a></b></span> <span class="reference-text"><a href="#CITEREFGoldbergWing2003">Goldberg & Wing 2003</a>, which cites: <dl><dd><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAmerican_College_of_Obstetricians_and_Gynecologists1999" class="citation journal cs1"><a href="/wiki/American_College_of_Obstetricians_and_Gynecologists" title="American College of Obstetricians and Gynecologists">American College of Obstetricians and Gynecologists</a> (November 1999). "Induction of labor with misoprostol". <i>ACOG Committee Opinion No. 228</i>. Washington, DC.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=ACOG+Committee+Opinion+No.+228&rft.atitle=Induction+of+labor+with+misoprostol&rft.date=1999-11&rft.au=American+College+of+Obstetricians+and+Gynecologists&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span></dd> <dd><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAmerican_College_of_Obstetricians_and_Gynecologists1999" class="citation journal cs1"><a href="/wiki/American_College_of_Obstetricians_and_Gynecologists" title="American College of Obstetricians and Gynecologists">American College of Obstetricians and Gynecologists</a> (November 1999). "Response to Searle's drug warning on misoprostol". <i>ACOG Committee Opinion No. 248</i>. Washington, DC.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=ACOG+Committee+Opinion+No.+248&rft.atitle=Response+to+Searle%27s+drug+warning+on+misoprostol&rft.date=1999-11&rft.au=American+College+of+Obstetricians+and+Gynecologists&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span></dd></dl> </span></li> <li id="cite_note-66"><span class="mw-cite-backlink"><b><a href="#cite_ref-66">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ema.europa.eu/en/documents/psusa/misoprostol-gynaecological-indication-labour-induction-list-nationally-authorised-medicinal-products/00010353/202005_en.pdf">"List of nationally authorized medicinal products"</a> <span class="cs1-format">(PDF)</span>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20211102122935/https://www.ema.europa.eu/en/documents/psusa/misoprostol-gynaecological-indication-labour-induction-list-nationally-authorised-medicinal-products/00010353/202005_en.pdf">Archived</a> <span class="cs1-format">(PDF)</span> from the original on 2 November 2021<span class="reference-accessdate">. Retrieved <span class="nowrap">29 June</span> 2022</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=List+of+nationally+authorized+medicinal+products&rft_id=https%3A%2F%2Fwww.ema.europa.eu%2Fen%2Fdocuments%2Fpsusa%2Fmisoprostol-gynaecological-indication-labour-induction-list-nationally-authorised-medicinal-products%2F00010353%2F202005_en.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMisoprostol" class="Z3988"></span></span> </li> <li id="cite_note-67"><span class="mw-cite-backlink"><b><a href="#cite_ref-67">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ema.europa.eu/en/documents/psusa/misoprostol-gynaecological-indication-labour-induction-list-nationally-authorised-medicinal-products/00010353/201905_en.pdf">"List of nationally authorised medicinal products"</a> <span class="cs1-format">(PDF)</span>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20220303093147/https://www.ema.europa.eu/en/documents/psusa/misoprostol-gynaecological-indication-labour-induction-list-nationally-authorised-medicinal-products/00010353/201905_en.pdf">Archived</a> <span class="cs1-format">(PDF)</span> from the original on 3 March 2022<span class="reference-accessdate">. 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href="/wiki/Philosophical_aspects_of_the_abortion_debate" title="Philosophical aspects of the abortion debate">Philosophical aspects</a></li></ul></li> <li><a href="/wiki/Abortion_law" title="Abortion law">Abortion law</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Movements</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abortion-rights_movements" class="mw-redirect" title="Abortion-rights movements">Abortion-rights movements</a></li> <li><a href="/wiki/Anti-abortion_movement" class="mw-redirect" title="Anti-abortion movement">Anti-abortion movements</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Issues</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abortion_and_mental_health" title="Abortion and mental health">Abortion and mental health</a></li> <li><a href="/wiki/Beginning_of_human_personhood" title="Beginning of human personhood">Beginning of human personhood</a></li> <li><a href="/wiki/Beginning_of_pregnancy_controversy" title="Beginning of pregnancy controversy">Beginning of pregnancy controversy</a></li> <li><a href="/wiki/Abortion%E2%80%93breast_cancer_hypothesis" title="Abortion–breast cancer hypothesis">Abortion-breast cancer hypothesis</a></li> <li><a href="/wiki/Anti-abortion_violence" title="Anti-abortion violence">Anti-abortion violence</a></li> <li><a href="/wiki/Abortion_under_communism" title="Abortion under communism">Abortion under communism</a></li> <li><a href="/wiki/Birth_control" title="Birth control">Birth control</a></li> <li><a href="/wiki/Crisis_pregnancy_center" title="Crisis pregnancy center">Crisis pregnancy center</a></li> <li><a href="/wiki/Ethical_aspects_of_abortion" class="mw-redirect" title="Ethical aspects of abortion">Ethical aspects of abortion</a></li> <li><a href="/wiki/Eugenics" title="Eugenics">Eugenics</a></li> <li><a href="/wiki/Fetal_rights" title="Fetal rights">Fetal rights</a></li> <li><a href="/wiki/Forced_abortion" title="Forced abortion">Forced abortion</a></li> <li><a href="/wiki/Genetics_and_abortion" title="Genetics and abortion">Genetics and abortion</a></li> <li><a href="/wiki/Late-term_abortion" class="mw-redirect" title="Late-term abortion">Late-term abortion</a></li> <li><a href="/wiki/Legalized_abortion_and_crime_effect" title="Legalized abortion and crime effect">Legalized abortion and crime effect</a></li> <li><a href="/wiki/Libertarian_perspectives_on_abortion" title="Libertarian perspectives on abortion">Libertarian perspectives on abortion</a></li> <li><a href="/wiki/Limit_of_viability" class="mw-redirect" title="Limit of viability">Limit of viability</a></li> <li><a href="/wiki/Malthusianism" title="Malthusianism">Malthusianism</a></li> <li><a href="/wiki/Men%27s_rights" class="mw-redirect" title="Men's rights">Men's rights</a></li> <li><a href="/wiki/Minors_and_abortion" title="Minors and abortion">Minors and abortion</a></li> <li><a href="/wiki/Misinformation_related_to_abortion" title="Misinformation related to abortion">Misinformation related to abortion</a></li> <li><a href="/wiki/Natalism" title="Natalism">Natalism</a></li> <li><a href="/wiki/One-child_policy" title="One-child policy">One-child policy</a></li> <li><a href="/wiki/Paternal_rights_and_abortion" title="Paternal rights and abortion">Paternal rights and abortion</a></li> <li><a href="/wiki/Post-abortion_care" title="Post-abortion care">Post-abortion care</a></li> <li><a href="/wiki/Prenatal_development" title="Prenatal development">Prenatal development</a></li> <li><a href="/wiki/Reproductive_rights" title="Reproductive rights">Reproductive rights</a></li> <li><a href="/wiki/Self-induced_abortion" title="Self-induced abortion">Self-induced abortion</a></li> <li><a href="/wiki/Sex-selective_abortion" title="Sex-selective abortion">Sex-selective abortion</a></li> <li><a href="/wiki/Sidewalk_counseling" title="Sidewalk counseling">Sidewalk counseling</a></li> <li><a href="/wiki/Societal_attitudes_towards_abortion" title="Societal attitudes towards abortion">Societal attitudes towards abortion</a></li> <li><a href="/wiki/Socialist_perspectives_on_abortion" title="Socialist perspectives on abortion">Socialism</a></li> <li><a href="/wiki/Termination_for_medical_reasons" title="Termination for medical reasons">Termination for medical reasons</a></li> <li><a href="/wiki/Toxic_abortion" title="Toxic abortion">Toxic abortion</a></li> <li><a href="/wiki/Unsafe_abortion" title="Unsafe abortion">Unsafe abortion</a></li> <li><a href="/wiki/Women%27s_rights" title="Women's rights">Women's rights</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">By country</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Abortion_in_Africa" title="Abortion in Africa">Africa</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abortion_in_Algeria" title="Abortion in Algeria">Algeria</a></li> <li><a href="/wiki/Abortion_in_Angola" title="Abortion in Angola">Angola</a></li> <li><a href="/wiki/Abortion_in_Benin" title="Abortion in Benin">Benin</a></li> <li><a href="/wiki/Abortion_in_Botswana" title="Abortion in Botswana">Botswana</a></li> <li><a href="/wiki/Abortion_in_Burkina_Faso" title="Abortion in Burkina Faso">Burkina Faso</a></li> <li><a href="/wiki/Abortion_in_Burundi" class="mw-redirect" title="Abortion in Burundi">Burundi</a></li> <li><a href="/wiki/Abortion_in_Cameroon" title="Abortion in Cameroon">Cameroon</a></li> <li><a href="/wiki/Abortion_in_Cape_Verde" title="Abortion in Cape Verde">Cape Verde</a></li> <li><a href="/wiki/Abortion_in_the_Central_African_Republic" title="Abortion in the Central African Republic">Central African Republic</a></li> <li><a href="/wiki/Abortion_in_Chad" title="Abortion in Chad">Chad</a></li> <li><a href="/wiki/Abortion_in_the_Comoros" title="Abortion in the Comoros">Comoros</a></li> <li><a href="/wiki/Abortion_in_Egypt" title="Abortion in Egypt">Egypt</a></li> <li><a href="/wiki/Abortion_in_Equatorial_Guinea" title="Abortion in Equatorial Guinea">Equatorial Guinea</a></li> <li><a href="/wiki/Abortion_in_Eswatini" title="Abortion in Eswatini">Eswatini</a></li> <li><a href="/wiki/Abortion_in_Gabon" title="Abortion in Gabon">Gabon</a></li> <li><a href="/wiki/Abortion_in_the_Gambia" title="Abortion in the Gambia">The Gambia</a></li> <li><a href="/wiki/Abortion_in_Ghana" title="Abortion in Ghana">Ghana</a></li> <li><a href="/wiki/Abortion_in_Guinea" title="Abortion in Guinea">Guinea</a></li> <li><a href="/wiki/Abortion_in_Kenya" title="Abortion in Kenya">Kenya</a></li> <li><a href="/wiki/Abortion_in_Lesotho" title="Abortion in Lesotho">Lesotho</a></li> <li><a href="/wiki/Abortion_in_Liberia" title="Abortion in Liberia">Liberia</a></li> <li><a href="/wiki/Abortion_in_Madagascar" title="Abortion in Madagascar">Madagascar</a></li> <li><a href="/wiki/Abortion_in_Malawi" title="Abortion in Malawi">Malawi</a></li> <li><a href="/wiki/Abortion_in_Namibia" title="Abortion in Namibia">Namibia</a></li> <li><a href="/wiki/Abortion_in_Nigeria" title="Abortion in Nigeria">Nigeria</a></li> <li><a href="/wiki/Abortion_in_Senegal" title="Abortion in Senegal">Senegal</a></li> <li><a href="/wiki/Abortion_in_Seychelles" title="Abortion in Seychelles">Seychelles</a></li> <li><a href="/wiki/Abortion_in_Sierra_Leone" title="Abortion in Sierra Leone">Sierra Leone</a></li> <li><a href="/wiki/Abortion_in_South_Africa" title="Abortion in South Africa">South Africa</a></li> <li><a href="/wiki/Abortion_in_Tanzania" title="Abortion in Tanzania">Tanzania</a></li> <li><a href="/wiki/Abortion_in_Togo" title="Abortion in Togo">Togo</a></li> <li><a href="/wiki/Abortion_in_Uganda" title="Abortion in Uganda">Uganda</a></li> <li><a href="/wiki/Abortion_in_Zambia" title="Abortion in Zambia">Zambia</a></li> <li><a href="/wiki/Abortion_in_Zimbabwe" title="Abortion in Zimbabwe">Zimbabwe</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Asia</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abortion_in_Afghanistan" title="Abortion in Afghanistan">Afghanistan</a></li> <li><a href="/wiki/Abortion_in_Armenia" title="Abortion in Armenia">Armenia</a></li> <li><a href="/wiki/Abortion_in_Azerbaijan" title="Abortion in Azerbaijan">Azerbaijan</a></li> <li><a href="/wiki/Abortion_in_Bahrain" title="Abortion in Bahrain">Bahrain</a></li> <li><a href="/wiki/Abortion_in_Bangladesh" title="Abortion in Bangladesh">Bangladesh</a></li> <li><a href="/wiki/Abortion_in_Bhutan" title="Abortion in Bhutan">Bhutan</a></li> <li><a href="/wiki/Abortion_in_Brunei" title="Abortion in Brunei">Brunei</a></li> <li><a href="/wiki/Abortion_in_Cambodia" title="Abortion in Cambodia">Cambodia</a></li> <li><a href="/wiki/Abortion_in_China" title="Abortion in China">China</a></li> <li><a href="/wiki/Abortion_in_Cyprus" title="Abortion in Cyprus">Cyprus</a></li> <li><a href="/wiki/Abortion_in_East_Timor" title="Abortion in East Timor">East Timor</a></li> <li><a href="/wiki/Abortion_in_Georgia_(country)" title="Abortion in Georgia (country)">Georgia</a></li> <li><a href="/wiki/Abortion_in_India" title="Abortion in India">India</a></li> <li><a href="/wiki/Abortion_in_Iran" title="Abortion in Iran">Iran</a></li> <li><a href="/wiki/Abortion_in_Israel" title="Abortion in Israel">Israel</a></li> <li><a href="/wiki/Abortion_in_Japan" title="Abortion in Japan">Japan</a></li> <li><a href="/wiki/Abortion_in_Kazakhstan" title="Abortion in Kazakhstan">Kazakhstan</a></li> <li><a href="/wiki/Abortion_in_North_Korea" title="Abortion in North Korea">North Korea</a></li> <li><a href="/wiki/Abortion_in_South_Korea" title="Abortion in South Korea">South Korea</a></li> <li><a href="/wiki/Abortion_in_Laos" title="Abortion in Laos">Laos</a></li> <li><a href="/wiki/Abortion_in_Lebanon" title="Abortion in Lebanon">Lebanon</a></li> <li><a href="/wiki/Abortion_in_Malaysia" title="Abortion in Malaysia">Malaysia</a></li> <li><a href="/wiki/Abortion_in_Nepal" title="Abortion in Nepal">Nepal</a></li> <li><a href="/wiki/Abortion_in_Northern_Cyprus" title="Abortion in Northern Cyprus">Northern Cyprus</a></li> <li><a href="/wiki/Abortion_in_the_Philippines" title="Abortion in the Philippines">Philippines</a></li> <li><a href="/wiki/Abortion_in_Qatar" title="Abortion in Qatar">Qatar</a></li> <li><a href="/wiki/Abortion_in_Saudi_Arabia" title="Abortion in Saudi Arabia">Saudi Arabia</a></li> <li><a href="/wiki/Abortion_in_Singapore" title="Abortion in Singapore">Singapore</a></li> <li><a href="/wiki/Abortion_in_Taiwan" title="Abortion in Taiwan">Taiwan</a></li> <li><a href="/wiki/Abortion_in_Turkey" title="Abortion in Turkey">Turkey</a></li> <li><a href="/wiki/Abortion_in_the_United_Arab_Emirates" class="mw-redirect" title="Abortion in the United Arab Emirates">United Arab Emirates</a></li> <li><a href="/wiki/Abortion_in_Vietnam" title="Abortion in Vietnam">Vietnam</a></li> <li><a href="/wiki/Abortion_in_Yemen" title="Abortion in Yemen">Yemen</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Abortion_in_Europe" title="Abortion in Europe">Europe</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abortion_in_Albania" title="Abortion in Albania">Albania</a></li> <li><a href="/wiki/Abortion_in_Andorra" title="Abortion in Andorra">Andorra</a></li> <li><a href="/wiki/Abortion_in_Austria" title="Abortion in Austria">Austria</a></li> <li><a href="/wiki/Abortion_in_Belarus" title="Abortion in Belarus">Belarus</a></li> <li><a href="/wiki/Abortion_in_Belgium" title="Abortion in Belgium">Belgium</a></li> <li><a href="/wiki/Abortion_in_Bosnia_and_Herzegovina" title="Abortion in Bosnia and Herzegovina">Bosnia and Herzegovina</a></li> <li><a href="/wiki/Abortion_in_Bulgaria" title="Abortion in Bulgaria">Bulgaria</a></li> <li><a href="/wiki/Abortion_in_Croatia" title="Abortion in Croatia">Croatia</a></li> <li><a href="/wiki/Abortion_in_Czech_Republic" class="mw-redirect" title="Abortion in Czech Republic">Czech Republic</a></li> <li><a href="/wiki/Abortion_in_Denmark" title="Abortion in Denmark">Denmark</a></li> <li><a href="/wiki/Abortion_in_Estonia" title="Abortion in Estonia">Estonia</a></li> <li><a href="/wiki/Abortion_in_Finland" title="Abortion in Finland">Finland</a></li> <li><a href="/wiki/Abortion_in_France" title="Abortion in France">France</a></li> <li><a href="/wiki/Abortion_in_Germany" title="Abortion in Germany">Germany</a></li> <li><a href="/wiki/Abortion_in_Greece" title="Abortion in Greece">Greece</a></li> <li><a href="/wiki/Abortion_in_Hungary" title="Abortion in Hungary">Hungary</a></li> <li><a href="/wiki/Abortion_in_Iceland" title="Abortion in Iceland">Iceland</a></li> <li><a href="/wiki/Abortion_in_the_Republic_of_Ireland" title="Abortion in the Republic of Ireland">Ireland</a></li> <li><a href="/wiki/Abortion_in_Italy" title="Abortion in Italy">Italy</a></li> <li><a href="/wiki/Abortion_in_Kazakhstan" title="Abortion in Kazakhstan">Kazakhstan</a></li> <li><a href="/wiki/Abortion_in_Latvia" title="Abortion in Latvia">Latvia</a></li> <li><a href="/wiki/Abortion_in_Liechtenstein" title="Abortion in Liechtenstein">Liechtenstein</a></li> <li><a href="/wiki/Abortion_in_Lithuania" title="Abortion in Lithuania">Lithuania</a></li> <li><a href="/wiki/Abortion_in_Luxembourg" title="Abortion in Luxembourg">Luxembourg</a></li> <li><a href="/wiki/Abortion_in_Malta" title="Abortion in Malta">Malta</a></li> <li><a href="/wiki/Abortion_in_Moldova" title="Abortion in Moldova">Moldova</a></li> <li><a href="/wiki/Abortion_in_Monaco" title="Abortion in Monaco">Monaco</a></li> <li><a href="/wiki/Abortion_in_Montenegro" title="Abortion in Montenegro">Montenegro</a></li> <li><a href="/wiki/Abortion_in_the_Netherlands" title="Abortion in the Netherlands">Netherlands</a></li> <li><a href="/wiki/Abortion_in_North_Macedonia" title="Abortion in North Macedonia">North Macedonia</a></li> <li><a href="/wiki/Abortion_in_Norway" title="Abortion in Norway">Norway</a></li> <li><a href="/wiki/Abortion_in_Poland" title="Abortion in Poland">Poland</a></li> <li><a href="/wiki/Abortion_in_Portugal" title="Abortion in Portugal">Portugal</a></li> <li><a href="/wiki/Abortion_in_Romania" title="Abortion in Romania">Romania</a></li> <li><a href="/wiki/Abortion_in_Russia" title="Abortion in Russia">Russia</a></li> <li><a href="/wiki/Abortion_in_San_Marino" title="Abortion in San Marino">San Marino</a></li> <li><a href="/wiki/Abortion_in_Serbia" title="Abortion in Serbia">Serbia</a></li> <li><a href="/wiki/Abortion_in_Slovakia" title="Abortion in Slovakia">Slovakia</a></li> <li><a href="/wiki/Abortion_in_Slovenia" title="Abortion in Slovenia">Slovenia</a></li> <li><a href="/wiki/Abortion_in_Spain" title="Abortion in Spain">Spain</a></li> <li><a href="/wiki/Abortion_in_Sweden" title="Abortion in Sweden">Sweden</a></li> <li><a href="/wiki/Abortion_in_Switzerland" title="Abortion in Switzerland">Switzerland</a></li> <li><a href="/wiki/Abortion_in_Ukraine" title="Abortion in Ukraine">Ukraine</a></li> <li><a href="/wiki/Abortion_in_the_United_Kingdom" title="Abortion in the United Kingdom">United Kingdom</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">North America</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abortion_in_the_Bahamas" title="Abortion in the Bahamas">Bahamas</a></li> <li><a href="/wiki/Abortion_in_Belize" title="Abortion in Belize">Belize</a></li> <li><a href="/wiki/Abortion_in_Canada" title="Abortion in Canada">Canada</a></li> <li><a href="/wiki/Abortion_in_Costa_Rica" title="Abortion in Costa Rica">Costa Rica</a></li> <li><a href="/wiki/Abortion_in_Cuba" title="Abortion in Cuba">Cuba</a></li> <li><a href="/wiki/Abortion_in_the_Dominican_Republic" title="Abortion in the Dominican Republic">Dominican Republic</a></li> <li><a href="/wiki/Abortion_in_El_Salvador" title="Abortion in El Salvador">El Salvador</a></li> <li><a href="/wiki/Abortion_in_Guatemala" title="Abortion in Guatemala">Guatemala</a></li> <li><a href="/wiki/Abortion_in_Honduras" title="Abortion in Honduras">Honduras</a></li> <li><a href="/wiki/Abortion_in_Mexico" title="Abortion in Mexico">Mexico</a></li> <li><a href="/wiki/Abortion_in_Nicaragua" title="Abortion in Nicaragua">Nicaragua</a></li> <li><a href="/wiki/Abortion_in_Panama" title="Abortion in Panama">Panama</a></li> <li><a href="/wiki/Abortion_in_Trinidad_and_Tobago" title="Abortion in Trinidad and Tobago">Trinidad and Tobago</a></li> <li><a href="/wiki/Abortion_law_in_the_United_States" class="mw-redirect" title="Abortion law in the United States">United States</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Oceania</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abortion_in_Australia" title="Abortion in Australia">Australia</a></li> <li><a href="/wiki/Abortion_in_the_Federated_States_of_Micronesia" title="Abortion in the Federated States of Micronesia">Micronesia</a></li> <li><a href="/wiki/Abortion_in_Fiji" title="Abortion in Fiji">Fiji</a></li> <li><a href="/wiki/Abortion_in_Kiribati" title="Abortion in Kiribati">Kiribati</a></li> <li><a href="/wiki/Abortion_in_the_Marshall_Islands" title="Abortion in the Marshall Islands">Marshall Islands</a></li> <li><a href="/wiki/Abortion_in_New_Zealand" title="Abortion in New Zealand">New Zealand</a></li> <li><a href="/wiki/Abortion_in_Papua_New_Guinea" title="Abortion in Papua New Guinea">Papua New Guinea</a></li> <li><a href="/wiki/Abortion_in_Samoa" title="Abortion in Samoa">Samoa</a></li> <li><a href="/wiki/Abortion_in_the_Solomon_Islands" title="Abortion in the Solomon Islands">Solomon Islands</a></li> <li><a href="/wiki/Abortion_in_Tonga" title="Abortion in Tonga">Tonga</a></li> <li><a href="/wiki/Abortion_in_Tuvalu" title="Abortion in Tuvalu">Tuvalu</a></li> <li><a href="/wiki/Abortion_in_Vanuatu" title="Abortion in Vanuatu">Vanuatu</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">South America</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abortion_in_Argentina" title="Abortion in Argentina">Argentina</a></li> <li><a href="/wiki/Abortion_in_Bolivia" title="Abortion in Bolivia">Bolivia</a></li> <li><a href="/wiki/Abortion_in_Brazil" title="Abortion in Brazil">Brazil</a></li> <li><a href="/wiki/Abortion_in_Chile" title="Abortion in Chile">Chile</a></li> <li><a href="/wiki/Abortion_in_Colombia" title="Abortion in Colombia">Colombia</a></li> <li><a href="/wiki/Abortion_in_Ecuador" title="Abortion in Ecuador">Ecuador</a></li> <li><a href="/wiki/Abortion_in_Guyana" title="Abortion in Guyana">Guyana</a></li> <li><a href="/wiki/Abortion_in_Paraguay" title="Abortion in Paraguay">Paraguay</a></li> <li><a href="/wiki/Abortion_in_Peru" title="Abortion in Peru">Peru</a></li> <li><a href="/wiki/Abortion_in_Suriname" title="Abortion in Suriname">Suriname</a></li> <li><a href="/wiki/Abortion_in_Uruguay" title="Abortion in Uruguay">Uruguay</a></li> <li><a href="/wiki/Abortion_in_Venezuela" title="Abortion in Venezuela">Venezuela</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Abortion_law" title="Abortion law">Law</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Category:Abortion_case_law" title="Category:Abortion case law">Case law</a></li> <li><a href="/wiki/Category:Abortion_constitutional_law" title="Category:Abortion constitutional law">Constitutional law</a></li> <li><a href="/wiki/History_of_abortion#Legal:_History_of_abortion_law" title="History of abortion">History of abortion law</a></li> <li><a href="/wiki/Abortion_law#National_laws" title="Abortion law">Laws by country</a></li> <li><a href="/wiki/Legal_protection_of_access_to_abortion" title="Legal protection of access to abortion">Buffer zones</a></li> <li><a href="/wiki/Conscientious_objection_to_abortion" title="Conscientious objection to abortion">Conscientious objection</a></li> <li><a href="/wiki/Fetal_rights" title="Fetal rights">Fetal protection</a></li> <li><a href="/wiki/Six-week_abortion_ban" class="mw-redirect" title="Six-week abortion ban">Six-week bans</a></li> <li><a href="/wiki/Informed_consent#Abortion" title="Informed consent">Informed consent</a></li> <li><a href="/wiki/Late-term_abortion#Legal_restrictions_on_later_abortion" class="mw-redirect" title="Late-term abortion">Late-term restrictions</a></li> <li><a href="/wiki/Minors_and_abortion" title="Minors and abortion">Parental involvement</a></li> <li><a href="/wiki/Paternal_rights_and_abortion#Men_and_abortion_in_law" title="Paternal rights and abortion">Spousal consent</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Methods</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Vacuum_aspiration" title="Vacuum aspiration">Vacuum aspiration</a></li> <li><a href="/wiki/Dilation_and_evacuation" title="Dilation and evacuation">Dilation and evacuation</a></li> <li><a href="/wiki/Dilation_and_curettage" title="Dilation and curettage">Dilation and curettage</a></li> <li><a href="/wiki/Intact_dilation_and_extraction" title="Intact dilation and extraction">Intact D&X</a></li> <li><a href="/wiki/Hysterotomy_abortion" title="Hysterotomy abortion">Hysterotomy</a></li> <li><a href="/wiki/Instillation_abortion" title="Instillation abortion">Instillation</a></li> <li><a href="/wiki/Menstrual_extraction" title="Menstrual extraction">Menstrual extraction</a></li> <li><a href="/wiki/Medical_abortion" title="Medical abortion">Medical abortion</a></li> <li><a href="/wiki/Abortifacient" title="Abortifacient">Abortifacient drugs</a> <ul><li><a href="/wiki/Methotrexate" title="Methotrexate">Methotrexate</a></li> <li><a href="/wiki/Mifepristone" title="Mifepristone">Mifepristone</a></li> <li><a class="mw-selflink selflink">Misoprostol</a></li> <li><a href="/wiki/Oxytocin" title="Oxytocin">Oxytocin</a></li></ul></li> <li><a href="/wiki/Self-induced_abortion" title="Self-induced abortion">Self-induced abortion</a></li> <li><a href="/wiki/Unsafe_abortion" title="Unsafe abortion">Unsafe abortion</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Religion_and_abortion" title="Religion and abortion">Religion</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Buddhism_and_abortion" title="Buddhism and abortion">Buddhism</a></li> <li><a href="/wiki/Christianity_and_abortion" title="Christianity and abortion">Christianity</a> <ul><li><a href="/wiki/Catholic_Church_and_abortion" title="Catholic Church and abortion">Catholicism</a></li></ul></li> <li><a href="/wiki/Hinduism_and_abortion" title="Hinduism and abortion">Hinduism</a></li> <li><a href="/wiki/Islam_and_abortion" title="Islam and abortion">Islam</a></li> <li><a href="/wiki/Judaism_and_abortion" title="Judaism and abortion">Judaism</a></li> <li><a href="/wiki/Scientology_and_abortion" title="Scientology and abortion">Scientology</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow hlist" colspan="2"><div> <ul><li><span class="noviewer" typeof="mw:File"><span title="Category"><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/16px-Symbol_category_class.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/23px-Symbol_category_class.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/31px-Symbol_category_class.svg.png 2x" data-file-width="180" data-file-height="185" /></span></span> <a href="/wiki/Category:Abortion" title="Category:Abortion">Category</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Eicosanoids" style="padding:3px"><table class="nowraplinks hlist mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Eicosanoids" title="Template:Eicosanoids"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Eicosanoids" title="Template talk:Eicosanoids"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Eicosanoids" title="Special:EditPage/Template:Eicosanoids"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Eicosanoids" style="font-size:114%;margin:0 4em"><a href="/wiki/Eicosanoid" title="Eicosanoid">Eicosanoids</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Precursor</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Arachidonic_acid" title="Arachidonic acid">Arachidonic acid</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Prostanoid" title="Prostanoid">Prostanoids</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Prostaglandin" title="Prostaglandin">Prostaglandins</a> (PG)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Precursor</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Prostaglandin_H2" title="Prostaglandin H2">H<sub>2</sub></a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Active</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">D/J</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Prostaglandin_D2" title="Prostaglandin D2">D<sub>2</sub></a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Prostaglandin_E" title="Prostaglandin E">E</a>/F</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Prostaglandin_E2" title="Prostaglandin E2">E<sub>2</sub> (Dinoprostone)</a></li></ul> <ul><li><a href="/wiki/Prostaglandin_E1" title="Prostaglandin E1">E<sub>1</sub> (Alprostadil)</a></li></ul> <ul><li><a href="/wiki/Prostaglandin_F2alpha" title="Prostaglandin F2alpha">F<sub>2α</sub> (Dinoprost)</a>:</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">I</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Prostacyclin" title="Prostacyclin">I<sub>2</sub> (Prostacyclin/Epoprostenol)</a>:</li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Thromboxane" title="Thromboxane">Thromboxanes</a> (TX)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Thromboxane_A2" title="Thromboxane A2">A<sub>2</sub></a></li> <li><a href="/wiki/Thromboxane_B2" title="Thromboxane B2">B<sub>2</sub></a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Leukotriene" title="Leukotriene">Leukotrienes</a> (LT)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Precursor</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Arachidonic_acid_5-hydroperoxide" title="Arachidonic acid 5-hydroperoxide">Arachidonic acid 5-hydroperoxide</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Initial</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Leukotriene_A4" title="Leukotriene A4">A<sub>4</sub></a></li> <li><a href="/wiki/Leukotriene_B4" title="Leukotriene B4">B<sub>4</sub></a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Slow-reacting_substance_of_anaphylaxis" title="Slow-reacting substance of anaphylaxis">SRS-A</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Leukotriene_C4" title="Leukotriene C4">C<sub>4</sub></a></li> <li><a href="/wiki/Leukotriene_D4" title="Leukotriene D4">D<sub>4</sub></a></li> <li><a href="/wiki/Leukotriene_E4" title="Leukotriene E4">E<sub>4</sub></a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Eoxin" title="Eoxin">Eoxins</a> (EX)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Precursor</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Arachidonic_acid_15-hydroperoxide&action=edit&redlink=1" class="new" title="Arachidonic acid 15-hydroperoxide (page does not exist)">Arachidonic acid 15-hydroperoxide</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Eoxins</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Eoxin_A4" title="Eoxin A4">A<sub>4</sub></a></li> <li><a href="/wiki/Eoxin_C4" title="Eoxin C4">C<sub>4</sub></a></li> <li><a href="/wiki/Eoxin_D4" title="Eoxin D4">D<sub>4</sub></a></li> <li><a href="/wiki/Eoxin_E4" title="Eoxin E4">E<sub>4</sub></a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Nonclassic_eicosanoid" title="Nonclassic eicosanoid">Nonclassic</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Lipoxin" title="Lipoxin">Lipoxins</a> (LX) (<a href="/wiki/Lipoxin" title="Lipoxin">A<sub>4</sub></a>, <a href="/wiki/Lipoxin" title="Lipoxin">B<sub>4</sub></a>)</li> <li><a href="/wiki/Virodhamine" title="Virodhamine">Virodhamine</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">By function</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Bronchoconstriction" title="Bronchoconstriction">bronchoconstriction</a></i> <ul><li><a href="/wiki/Prostaglandin_D2" title="Prostaglandin D2">PGD<sub>2</sub></a></li> <li><a href="/wiki/Thromboxane_A2" title="Thromboxane A2">TXA<sub>2</sub></a></li> <li><a href="/wiki/Leukotriene_C4" title="Leukotriene C4">LTC<sub>4</sub></a></li> <li><a href="/wiki/Leukotriene_D4" title="Leukotriene D4">LTD<sub>4</sub></a></li> <li><a href="/wiki/Leukotriene_E4" title="Leukotriene E4">LTE<sub>4</sub></a></li></ul></li></ul> <ul><li><i><a href="/wiki/Vasoconstriction" title="Vasoconstriction">vasoconstriction</a></i> <ul><li><a href="/wiki/Prostaglandin_F2alpha" title="Prostaglandin F2alpha">PGF<sub>2α</sub></a></li> <li><a href="/wiki/Thromboxane_A2" title="Thromboxane A2">TXA<sub>2</sub></a></li> <li><a href="/wiki/Thromboxane_B2" title="Thromboxane B2">TXB<sub>2</sub></a></li></ul></li> <li><i><a href="/wiki/Vasodilation" title="Vasodilation">vasodilation</a></i> <ul><li><a href="/wiki/Prostaglandin_E2" title="Prostaglandin E2">PGE<sub>2</sub></a></li> <li><a href="/wiki/Prostacyclin" title="Prostacyclin">PGI<sub>2</sub></a></li> <li><a href="/wiki/Leukotriene_C4" title="Leukotriene C4">LTC<sub>4</sub></a></li> <li><a href="/wiki/Leukotriene_D4" title="Leukotriene D4">LTD<sub>4</sub></a></li> <li><a href="/wiki/Leukotriene_E4" title="Leukotriene E4">LTE<sub>4</sub></a></li></ul></li></ul> <ul><li><i><a href="/wiki/Platelet" title="Platelet">platelets</a>: induce</i> <ul><li><a href="/wiki/Thromboxane_A2" title="Thromboxane A2">TXA<sub>2</sub></a></li></ul></li> <li><i>inhibit</i> <ul><li><a href="/wiki/Prostaglandin_D2" title="Prostaglandin D2">PGD<sub>2</sub></a></li> <li><a href="/wiki/Prostacyclin" title="Prostacyclin">PGI<sub>2</sub></a></li></ul></li> <li><i><a href="/wiki/Leukocyte" class="mw-redirect" title="Leukocyte">leukocytes</a>: induce</i> <ul><li><a href="/wiki/Thromboxane_A2" title="Thromboxane A2">TXA<sub>2</sub></a></li> <li><a href="/wiki/Leukotriene_B4" title="Leukotriene B4">LTB<sub>4</sub></a></li></ul></li> <li><i>inhibit</i> <ul><li><a href="/wiki/Prostaglandin_D2" title="Prostaglandin D2">PGD<sub>2</sub></a></li> <li><a href="/wiki/Prostaglandin_E2" title="Prostaglandin E2">PGE<sub>2</sub></a></li></ul></li></ul> <ul><li><i><a href="/wiki/Fever" title="Fever">fever</a> stimulation:</i> <ul><li><a href="/wiki/Prostaglandin_E2" title="Prostaglandin E2">PGE<sub>2</sub></a></li></ul></li></ul> <ul><li><i><a href="/wiki/Childbirth" title="Childbirth">labor</a> stimulation:</i> <ul><li><a href="/wiki/Prostaglandin_E2" title="Prostaglandin E2">PGE<sub>2</sub></a> (Dinoprostone)</li> <li><a href="/wiki/Prostaglandin_F2alpha" title="Prostaglandin F2alpha">PGF<sub>2α</sub></a> (Dinoprost)</li></ul></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Obstetric_drugs" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Obstetric_drugs" title="Template:Obstetric drugs"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Obstetric_drugs" title="Template talk:Obstetric drugs"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Obstetric_drugs" title="Special:EditPage/Template:Obstetric drugs"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Obstetric_drugs" style="font-size:114%;margin:0 4em">Obstetric drugs</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Induction and augmentation of labour</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Prostaglandin_F2alpha" title="Prostaglandin F2alpha">Dinoprost</a></li> <li><a href="/wiki/Prostaglandin_E2" title="Prostaglandin E2">Dinoprostone</a></li> <li><a href="/wiki/Oxytocin_(medication)" title="Oxytocin (medication)">Oxytocin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Prevention and treatment of hemorrhage</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Carboprost" title="Carboprost">Carboprost</a></li> <li><a href="/wiki/Carbetocin" title="Carbetocin">Carbetocin</a></li> <li><a href="/wiki/Demoxytocin" title="Demoxytocin">Demoxytocin</a></li> <li><a href="/wiki/Ergometrine" title="Ergometrine">Ergometrine</a></li> <li><a href="/wiki/Methylergonovine" class="mw-redirect" title="Methylergonovine">Methylergonovine</a></li> <li><a href="/wiki/Oxytocin_(medication)" title="Oxytocin (medication)">Oxytocin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Induction of abortion</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a class="mw-selflink selflink">Misoprostol</a></li> <li><a href="/wiki/Mifepristone" title="Mifepristone">Mifepristone</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"></div><div role="navigation" class="navbox" aria-labelledby="Drugs_for_peptic_ulcer_and_GERD/GORD_(A02B)" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Drugs_for_peptic_ulcer_and_GORD" title="Template:Drugs for peptic ulcer and GORD"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Drugs_for_peptic_ulcer_and_GORD" title="Template talk:Drugs for peptic ulcer and GORD"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Drugs_for_peptic_ulcer_and_GORD" title="Special:EditPage/Template:Drugs for peptic ulcer and GORD"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Drugs_for_peptic_ulcer_and_GERD/GORD_(A02B)" style="font-size:114%;margin:0 4em">Drugs for <a href="/wiki/Peptic_ulcer" class="mw-redirect" title="Peptic ulcer">peptic ulcer</a> and <a href="/wiki/Gastroesophageal_reflux_disease" title="Gastroesophageal reflux disease">GERD/GORD</a> (<a href="/wiki/ATC_code_A02#A02B" title="ATC code A02">A02B</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/H2_antagonist" class="mw-redirect" title="H2 antagonist">H<sub>2</sub> antagonists</a> ("-tidine")</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cimetidine" title="Cimetidine">Cimetidine</a></li> <li><a href="/wiki/Famotidine" title="Famotidine">Famotidine</a></li> <li><a href="/wiki/Lafutidine" title="Lafutidine">Lafutidine</a></li> <li><a href="/wiki/Lavoltidine" title="Lavoltidine">Lavoltidine (loxtidine)</a></li> <li><a href="/wiki/Nizatidine" title="Nizatidine">Nizatidine</a></li> <li><a href="/wiki/Ranitidine" title="Ranitidine">Ranitidine</a><sup>#‡</sup></li> <li><a href="/wiki/Roxatidine_acetate" title="Roxatidine acetate">Roxatidine</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Prostaglandin" title="Prostaglandin">Prostaglandins</a> (E)/<br /><a href="/wiki/Prostaglandin_analogue" title="Prostaglandin analogue">analogues</a> ("-prost-")</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a class="mw-selflink selflink">Misoprostol</a></li> <li><a href="/wiki/Enprostil" title="Enprostil">Enprostil</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Proton-pump_inhibitor" title="Proton-pump inhibitor">Proton-pump inhibitors</a> <br />("-prazole")</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Azeloprazole" title="Azeloprazole">Azeloprazole</a></li> <li><a href="/wiki/Dexlansoprazole" title="Dexlansoprazole">Dexlansoprazole</a></li> <li><a href="/wiki/Esomeprazole" title="Esomeprazole">Esomeprazole</a></li> <li><a href="/wiki/Ilaprazole" title="Ilaprazole">Ilaprazole</a></li> <li><a href="/wiki/Lansoprazole" title="Lansoprazole">Lansoprazole</a></li> <li><a href="/wiki/Omeprazole" title="Omeprazole">Omeprazole</a><sup>#</sup></li> <li><a href="/wiki/Pantoprazole" title="Pantoprazole">Pantoprazole</a></li> <li><a href="/w/index.php?title=Picoprazole&action=edit&redlink=1" class="new" title="Picoprazole (page does not exist)">Picoprazole</a></li> <li><a href="/wiki/Rabeprazole" title="Rabeprazole">Rabeprazole</a></li> <li><a href="/wiki/Tenatoprazole" title="Tenatoprazole">Tenatoprazole</a></li> <li><a href="/wiki/Timoprazole" title="Timoprazole">Timoprazole</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Potassium-competitive_acid_blocker" class="mw-redirect" title="Potassium-competitive acid blocker">Potassium-competitive <br />acid blockers</a> ("-prazan")</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Linaprazan" title="Linaprazan">Linaprazan</a></li> <li><a href="/wiki/Revaprazan" title="Revaprazan">Revaprazan</a></li> <li><a href="/w/index.php?title=Soraprazan&action=edit&redlink=1" class="new" title="Soraprazan (page does not exist)">Soraprazan</a></li> <li><a href="/wiki/Vonoprazan" title="Vonoprazan">Vonoprazan</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Others</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Aceglutamide_aluminum" class="mw-redirect" title="Aceglutamide aluminum">Aceglutamide aluminum</a></li> <li><a href="/wiki/Acetoxolone" title="Acetoxolone">Acetoxolone</a></li> <li><a href="/wiki/Alginic_acid" title="Alginic acid">Alginic acid</a></li> <li><a href="/wiki/Arbaclofen_placarbil" title="Arbaclofen placarbil">Arbaclofen placarbil</a></li> <li><a href="/wiki/Bismuth_subcitrate" title="Bismuth subcitrate">Bismuth subcitrate</a></li> <li><a href="/wiki/Carbenoxolone" title="Carbenoxolone">Carbenoxolone</a></li> <li><a href="/wiki/Cetraxate" title="Cetraxate">Cetraxate</a></li> <li><a href="/wiki/Gefarnate" title="Gefarnate">Gefarnate</a></li> <li><a href="/wiki/Irsogladine" title="Irsogladine">Irsogladine</a></li> <li><a href="/wiki/Lesogaberan" title="Lesogaberan">Lesogaberan</a></li> <li><a href="/wiki/Pirenzepine" title="Pirenzepine">Pirenzepine</a></li> <li><a href="/wiki/Proglumide" title="Proglumide">Proglumide</a></li> <li><a href="/wiki/Rebamipide" title="Rebamipide">Rebamipide</a></li> <li><a href="/wiki/Sucralfate" title="Sucralfate">Sucralfate</a></li> <li><a href="/wiki/Sulglicotide" title="Sulglicotide">Sulglicotide</a></li> <li><a href="/wiki/Telenzepine" title="Telenzepine">Telenzepine</a></li> <li><a href="/wiki/Teprenone" title="Teprenone">Teprenone</a></li> <li><a href="/wiki/Troxipide" title="Troxipide">Troxipide</a></li> <li><a href="/wiki/Zinc_L-carnosine" title="Zinc L-carnosine">Zinc L-carnosine</a></li> <li><a href="/wiki/Zolimidine" title="Zolimidine">Zolimidine</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Combinations</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Bismuth_subcitrate/metronidazole/tetracycline" title="Bismuth subcitrate/metronidazole/tetracycline">Bismuth subcitrate/metronidazole/tetracycline</a></li> <li><a href="/wiki/Omeprazole/amoxicillin/rifabutin" title="Omeprazole/amoxicillin/rifabutin">Omeprazole/amoxicillin/rifabutin</a></li> <li><a href="/wiki/Vonoprazan/amoxicillin" title="Vonoprazan/amoxicillin">Vonoprazan/amoxicillin</a></li> <li><a href="/wiki/Vonoprazan/amoxicillin/clarithromycin" title="Vonoprazan/amoxicillin/clarithromycin">Vonoprazan/amoxicillin/clarithromycin</a></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>See also: <a href="/wiki/Helicobacter_pylori_eradication_protocols" title="Helicobacter pylori eradication protocols"><i>Helicobacter pylori</i> eradication protocols</a></i></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background: transparent; padding: 0px;"><div><div class="hlist"> <ul><li><sup>#</sup><a href="/wiki/WHO_Model_List_of_Essential_Medicines" title="WHO Model List of Essential Medicines">WHO-EM</a></li> <li><sup>‡</sup><a href="/wiki/List_of_withdrawn_drugs" title="List of withdrawn drugs">Withdrawn</a> from market</li> <li><a href="/wiki/Clinical_trial" title="Clinical trial">Clinical trials</a>: <ul><li><sup>†</sup><a href="/wiki/Phases_of_clinical_research#Phase_III" title="Phases of clinical research">Phase III</a></li> <li><sup>§</sup>Never to phase III</li></ul></li></ul> </div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"></div><div role="navigation" class="navbox" aria-labelledby="Uterotonics/labor_inducers/oxytocics_(G02A)" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Uterotonics" title="Template:Uterotonics"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Uterotonics" title="Template talk:Uterotonics"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Uterotonics" title="Special:EditPage/Template:Uterotonics"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Uterotonics/labor_inducers/oxytocics_(G02A)" style="font-size:114%;margin:0 4em"><a href="/wiki/Uterotonic" title="Uterotonic">Uterotonics</a>/<a href="/wiki/Labor_induction" title="Labor induction">labor inducers</a>/<a href="/wiki/Oxytocic" class="mw-redirect" title="Oxytocic">oxytocics</a> (<a href="/wiki/ATC_code_G02#G02A" title="ATC code G02">G02A</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cervical_dilation" title="Cervical dilation">Cervical ripening</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Ergot_alkaloid" class="mw-redirect" title="Ergot alkaloid">Ergot alkaloids</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Acetergamine" title="Acetergamine">Acetergamine</a></li> <li><a href="/wiki/Ergometrine" title="Ergometrine">Ergometrine</a><sup>#</sup> (<a href="/wiki/Oxytocin/ergometrine" title="Oxytocin/ergometrine">Syntometrine</a>)</li> <li><a href="/wiki/Methylergometrine" title="Methylergometrine">Methylergometrine</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Prostaglandin" title="Prostaglandin">Prostaglandins</a> and<br /> <a href="/wiki/Prostaglandin_analogue" title="Prostaglandin analogue">analogues</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>E: <a class="mw-selflink selflink">Misoprostol/E1</a><sup>#</sup></li> <li><a href="/wiki/Gemeprost" title="Gemeprost">Gemeprost/E1</a></li> <li><a href="/wiki/Prostaglandin_E2" title="Prostaglandin E2">Dinoprostone/E2</a></li> <li><a href="/wiki/Sulprostone" title="Sulprostone">Sulprostone/E2</a><br /></li></ul> <ul><li>F: <a href="/wiki/Prostaglandin_F2alpha" title="Prostaglandin F2alpha">Dinoprost/F2α</a></li> <li><a href="/wiki/Carboprost" title="Carboprost">Carboprost/F2α</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Contraction_(childbirth)" class="mw-redirect" title="Contraction (childbirth)">Contraction induction</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Oxytocin_(medication)" title="Oxytocin (medication)">Oxytocin</a><sup>#</sup></li> <li><a href="/wiki/Carbetocin" title="Carbetocin">Carbetocin</a></li> <li><a href="/wiki/Demoxytocin" title="Demoxytocin">Demoxytocin</a></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"><div class="hlist"> <ul><li><sup>#</sup><a href="/wiki/WHO_Model_List_of_Essential_Medicines" title="WHO Model List of Essential Medicines">WHO-EM</a></li> <li><sup>‡</sup><a href="/wiki/List_of_withdrawn_drugs" title="List of withdrawn drugs">Withdrawn</a> from market</li> <li><a href="/wiki/Clinical_trial" title="Clinical trial">Clinical trials</a>: <ul><li><sup>†</sup><a href="/wiki/Phases_of_clinical_research#Phase_III" title="Phases of clinical research">Phase III</a></li> <li><sup>§</sup>Never to phase III</li></ul></li></ul> </div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Prostanoid_signaling_modulators" style="padding:3px"><table class="nowraplinks hlist mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Prostanoid_signaling_modulators" title="Template:Prostanoid signaling modulators"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Prostanoid_signaling_modulators" title="Template talk:Prostanoid signaling modulators"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Prostanoid_signaling_modulators" title="Special:EditPage/Template:Prostanoid signaling modulators"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Prostanoid_signaling_modulators" style="font-size:114%;margin:0 4em"><a href="/wiki/Prostanoid" title="Prostanoid">Prostanoid</a> <a href="/wiki/Cell_signaling" title="Cell signaling">signaling</a> <a href="/wiki/Receptor_modulator" title="Receptor modulator">modulators</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Receptor_(biochemistry)" title="Receptor (biochemistry)">Receptor</a><br /><small>(<a href="/wiki/Ligand_(biochemistry)" title="Ligand (biochemistry)">ligands</a>)</small></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Prostaglandin_D2_receptor" title="Prostaglandin D2 receptor"><abbr title="Prostaglandin D2 receptor">DP (D<sub>2</sub>)</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Prostaglandin D2 receptor</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Prostaglandin_D2_receptor_1" class="mw-redirect" title="Prostaglandin D2 receptor 1"><abbr title="Prostaglandin D2 receptor 1">DP<sub>1</sub></abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Prostaglandin D2 receptor 1</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b>Agonists:</b> <a href="/wiki/Prostaglandin_D2" title="Prostaglandin D2">Prostaglandin D<sub>2</sub></a></li> <li><a href="/wiki/Treprostinil" title="Treprostinil">Treprostinil</a></li></ul> <ul><li><b>Antagonists:</b> <a href="/w/index.php?title=Asapiprant&action=edit&redlink=1" class="new" title="Asapiprant (page does not exist)">Asapiprant</a></li> <li><a href="/wiki/Laropiprant" title="Laropiprant">Laropiprant</a></li> <li><a href="/w/index.php?title=Vidupiprant&action=edit&redlink=1" class="new" title="Vidupiprant (page does not exist)">Vidupiprant</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Prostaglandin_D2_receptor_2" class="mw-redirect" title="Prostaglandin D2 receptor 2"><abbr title="Prostaglandin D2 receptor 2">DP<sub>2</sub></abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Prostaglandin D2 receptor 2</span></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b>Agonists:</b> <a href="/wiki/Indometacin" title="Indometacin">Indometacin</a></li> <li><a href="/wiki/Prostaglandin_D2" title="Prostaglandin D2">Prostaglandin D<sub>2</sub></a></li></ul> <ul><li><b>Antagonists:</b> <a href="/w/index.php?title=ADC-3680&action=edit&redlink=1" class="new" title="ADC-3680 (page does not exist)">ADC-3680</a></li> <li><a href="/w/index.php?title=AZD-1981&action=edit&redlink=1" class="new" title="AZD-1981 (page does not exist)">AZD-1981</a></li> <li><a href="/w/index.php?title=Bay_U3405&action=edit&redlink=1" class="new" title="Bay U3405 (page does not exist)">Bay U3405</a></li> <li><a href="/wiki/Fevipiprant" title="Fevipiprant">Fevipiprant</a></li> <li><a href="/w/index.php?title=MK-1029&action=edit&redlink=1" class="new" title="MK-1029 (page does not exist)">MK-1029</a></li> <li><a href="/w/index.php?title=MK-7246&action=edit&redlink=1" class="new" title="MK-7246 (page does not exist)">MK-7246</a></li> <li><a href="/w/index.php?title=QAV-680&action=edit&redlink=1" class="new" title="QAV-680 (page does not exist)">QAV-680</a></li> <li><a href="/wiki/Ramatroban" title="Ramatroban">Ramatroban</a></li> <li><a href="/wiki/Setipiprant" title="Setipiprant">Setipiprant</a></li> <li><a href="/w/index.php?title=Timapiprant&action=edit&redlink=1" class="new" title="Timapiprant (page does not exist)">Timapiprant</a></li> <li><a href="/w/index.php?title=TM30089&action=edit&redlink=1" class="new" title="TM30089 (page does not exist)">TM30089</a></li> <li><a href="/w/index.php?title=Vidupiprant&action=edit&redlink=1" class="new" title="Vidupiprant (page does not exist)">Vidupiprant</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Prostaglandin_E2_receptor" title="Prostaglandin E2 receptor"><abbr title="Prostaglandin E2 receptor">EP (E<sub>2</sub>)</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Prostaglandin E2 receptor</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Prostaglandin_EP1_receptor" title="Prostaglandin EP1 receptor"><abbr title="Prostaglandin EP1 receptor">EP<sub>1</sub></abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Prostaglandin EP1 receptor</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b>Agonists:</b> <a href="/wiki/Beraprost" title="Beraprost">Beraprost</a></li> <li><a href="/wiki/Enprostil" title="Enprostil">Enprostil</a></li> <li><a href="/wiki/Iloprost" title="Iloprost">Iloprost (ciloprost)</a></li> <li><a href="/wiki/Latanoprost" title="Latanoprost">Latanoprost</a></li> <li><a href="/wiki/Lubiprostone" title="Lubiprostone">Lubiprostone</a></li> <li><a class="mw-selflink selflink">Misoprostol</a></li> <li><a href="/wiki/Prostaglandin_E1" title="Prostaglandin E1">Prostaglandin E<sub>1</sub> (alprostadil)</a></li> <li><a href="/wiki/Prostaglandin_E2" title="Prostaglandin E2">Prostaglandin E<sub>2</sub> (dinoprostone)</a></li> <li><a href="/wiki/Sulprostone" title="Sulprostone">Sulprostone</a></li></ul> <ul><li><b>Antagonists:</b> <a href="/w/index.php?title=AH-6809&action=edit&redlink=1" class="new" title="AH-6809 (page does not exist)">AH-6809</a></li> <li><a href="/w/index.php?title=ONO-8130&action=edit&redlink=1" class="new" title="ONO-8130 (page does not exist)">ONO-8130</a></li> <li><a href="/w/index.php?title=SC-19220&action=edit&redlink=1" class="new" title="SC-19220 (page does not exist)">SC-19220</a></li> <li><a href="/w/index.php?title=SC-51089&action=edit&redlink=1" class="new" title="SC-51089 (page does not exist)">SC-51089</a></li> <li><a href="/w/index.php?title=SC-51322&action=edit&redlink=1" class="new" title="SC-51322 (page does not exist)">SC-51322</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Prostaglandin_EP2_receptor" title="Prostaglandin EP2 receptor"><abbr title="Prostaglandin EP2 receptor">EP<sub>2</sub></abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Prostaglandin EP2 receptor</span></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b>Agonists:</b> <a href="/w/index.php?title=Butaprost&action=edit&redlink=1" class="new" title="Butaprost (page does not exist)">Butaprost</a></li> <li><a class="mw-selflink selflink">Misoprostol</a></li> <li><a href="/wiki/Prostaglandin_E1" title="Prostaglandin E1">Prostaglandin E<sub>1</sub> (alprostadil)</a></li> <li><a href="/wiki/Prostaglandin_E2" title="Prostaglandin E2">Prostaglandin E<sub>2</sub> (dinoprostone)</a></li> <li><a href="/wiki/Treprostinil" title="Treprostinil">Treprostinil</a></li></ul> <ul><li><b>Antagonists:</b> <a href="/w/index.php?title=AH-6809&action=edit&redlink=1" class="new" title="AH-6809 (page does not exist)">AH-6809</a></li> <li><a href="/w/index.php?title=PF-04418948&action=edit&redlink=1" class="new" title="PF-04418948 (page does not exist)">PF-04418948</a></li> <li><a href="/w/index.php?title=TG_4-155&action=edit&redlink=1" class="new" title="TG 4-155 (page does not exist)">TG 4-155</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Prostaglandin_EP3_receptor" title="Prostaglandin EP3 receptor"><abbr title="Prostaglandin EP3 receptor">EP<sub>3</sub></abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Prostaglandin EP3 receptor</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b>Agonists:</b> <a href="/wiki/Beraprost" title="Beraprost">Beraprost</a></li> <li><a href="/w/index.php?title=Carbacyclin&action=edit&redlink=1" class="new" title="Carbacyclin (page does not exist)">Carbacyclin</a></li> <li><a href="/w/index.php?title=Cicaprost&action=edit&redlink=1" class="new" title="Cicaprost (page does not exist)">Cicaprost</a></li> <li><a href="/wiki/Enprostil" title="Enprostil">Enprostil</a></li> <li><a href="/wiki/Iloprost" title="Iloprost">Iloprost (ciloprost)</a></li> <li><a href="/w/index.php?title=Isocarbacyclin&action=edit&redlink=1" class="new" title="Isocarbacyclin (page does not exist)">Isocarbacyclin</a></li> <li><a href="/wiki/Latanoprost" title="Latanoprost">Latanoprost</a></li> <li><a class="mw-selflink selflink">Misoprostol</a></li> <li><a href="/wiki/Prostaglandin_D2" title="Prostaglandin D2">Prostaglandin D<sub>2</sub></a></li> <li><a href="/wiki/Prostaglandin_E1" title="Prostaglandin E1">Prostaglandin E<sub>1</sub> (alprostadil)</a></li> <li><a href="/wiki/Prostaglandin_E2" title="Prostaglandin E2">Prostaglandin E<sub>2</sub> (dinoprostone)</a></li> <li><a href="/w/index.php?title=Remiprostol&action=edit&redlink=1" class="new" title="Remiprostol (page does not exist)">Remiprostol</a></li> <li><a href="/wiki/Ricinoleic_acid" title="Ricinoleic acid">Ricinoleic acid</a></li> <li><a href="/wiki/Sulprostone" title="Sulprostone">Sulprostone</a></li></ul> <ul><li><b>Antagonists:</b> <a href="/w/index.php?title=L-798106&action=edit&redlink=1" class="new" title="L-798106 (page does not exist)">L-798106</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Prostaglandin_EP4_receptor" title="Prostaglandin EP4 receptor"><abbr title="Prostaglandin EP4 receptor">EP<sub>4</sub></abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Prostaglandin EP4 receptor</span></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b>Agonists:</b> <a href="/wiki/Lubiprostone" title="Lubiprostone">Lubiprostone</a></li> <li><a class="mw-selflink selflink">Misoprostol</a></li> <li><a href="/wiki/Prostaglandin_E1" title="Prostaglandin E1">Prostaglandin E<sub>1</sub> (alprostadil)</a></li> <li><a href="/wiki/Prostaglandin_E2" title="Prostaglandin E2">Prostaglandin E<sub>2</sub> (dinoprostone)</a></li> <li><a href="/w/index.php?title=TCS-2510&action=edit&redlink=1" class="new" title="TCS-2510 (page does not exist)">TCS-2510</a></li></ul> <ul><li><b>Antagonists:</b> <a href="/wiki/Grapiprant" title="Grapiprant">Grapiprant</a></li> <li><a href="/w/index.php?title=GW-627368&action=edit&redlink=1" class="new" title="GW-627368 (page does not exist)">GW-627368</a></li> <li><a href="/w/index.php?title=L-161982&action=edit&redlink=1" class="new" title="L-161982 (page does not exist)">L-161982</a></li> <li><a href="/w/index.php?title=ONO-AE3-208&action=edit&redlink=1" class="new" title="ONO-AE3-208 (page does not exist)">ONO-AE3-208</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;">Unsorted</th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b>Agonists:</b> <a href="/w/index.php?title=16,16-Dimethyl_Prostaglandin_E2&action=edit&redlink=1" class="new" title="16,16-Dimethyl Prostaglandin E2 (page does not exist)">16,16-Dimethyl Prostaglandin E<sub>2</sub></a></li> <li><a href="/w/index.php?title=Aganepag&action=edit&redlink=1" class="new" title="Aganepag (page does not exist)">Aganepag</a></li> <li><a href="/wiki/Carboprost" title="Carboprost">Carboprost</a></li> <li><a href="/w/index.php?title=Evatanepag&action=edit&redlink=1" class="new" title="Evatanepag (page does not exist)">Evatanepag</a></li> <li><a href="/wiki/Gemeprost" title="Gemeprost">Gemeprost</a></li> <li><a href="/w/index.php?title=Nocloprost&action=edit&redlink=1" class="new" title="Nocloprost (page does not exist)">Nocloprost</a></li> <li><a href="/wiki/Omidenepag" title="Omidenepag">Omidenepag</a></li> <li><a href="/wiki/Prostaglandin_F2%CE%B1" class="mw-redirect" title="Prostaglandin F2α">Prostaglandin F<sub>2α</sub> (dinoprost)</a></li> <li><a href="/w/index.php?title=Simenepag&action=edit&redlink=1" class="new" title="Simenepag (page does not exist)">Simenepag</a></li> <li><a href="/w/index.php?title=Taprenepag&action=edit&redlink=1" class="new" title="Taprenepag (page does not exist)">Taprenepag</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Prostaglandin_F_receptor" title="Prostaglandin F receptor"><abbr title="Prostaglandin F receptor">FP (F<sub>2α</sub>)</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Prostaglandin F receptor</span></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b>Agonists:</b> <a href="/wiki/Alfaprostol" title="Alfaprostol">Alfaprostol</a></li> <li><a href="/wiki/Bimatoprost" title="Bimatoprost">Bimatoprost</a></li> <li><a href="/wiki/Carboprost" title="Carboprost">Carboprost</a></li> <li><a href="/wiki/Cloprostenol" title="Cloprostenol">Cloprostenol</a></li> <li><a href="/wiki/Enprostil" title="Enprostil">Enprostil</a></li> <li><a href="/w/index.php?title=Fluprostenol&action=edit&redlink=1" class="new" title="Fluprostenol (page does not exist)">Fluprostenol</a></li> <li><a href="/wiki/Latanoprost" title="Latanoprost">Latanoprost</a></li> <li><a href="/wiki/Prostaglandin_D2" title="Prostaglandin D2">Prostaglandin D<sub>2</sub></a></li> <li><a href="/wiki/Prostaglandin_F2%CE%B1" class="mw-redirect" title="Prostaglandin F2α">Prostaglandin F<sub>2α</sub> (dinoprost)</a></li> <li><a href="/w/index.php?title=Sulotroban&action=edit&redlink=1" class="new" title="Sulotroban (page does not exist)">Sulotroban</a></li> <li><a href="/wiki/Tafluprost" title="Tafluprost">Tafluprost</a></li> <li><a href="/wiki/Travoprost" title="Travoprost">Travoprost</a></li> <li><a href="/wiki/Unoprostone" title="Unoprostone">Unoprostone</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Prostacyclin_receptor" title="Prostacyclin receptor"><abbr title="Prostacyclin receptor">IP (I<sub>2</sub>)</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Prostacyclin receptor</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b>Agonists:</b> <a href="/w/index.php?title=ACT-333679&action=edit&redlink=1" class="new" title="ACT-333679 (page does not exist)">ACT-333679</a></li> <li><a href="/w/index.php?title=AFP-07&action=edit&redlink=1" class="new" title="AFP-07 (page does not exist)">AFP-07</a></li> <li><a href="/wiki/Beraprost" title="Beraprost">Beraprost</a></li> <li><a href="/w/index.php?title=BMY-45778&action=edit&redlink=1" class="new" title="BMY-45778 (page does not exist)">BMY-45778</a></li> <li><a href="/w/index.php?title=Carbacyclin&action=edit&redlink=1" class="new" title="Carbacyclin (page does not exist)">Carbacyclin</a></li> <li><a href="/w/index.php?title=Cicaprost&action=edit&redlink=1" class="new" title="Cicaprost (page does not exist)">Cicaprost</a></li> <li><a href="/wiki/Iloprost" title="Iloprost">Iloprost (ciloprost)</a></li> <li><a href="/w/index.php?title=Isocarbacyclin&action=edit&redlink=1" class="new" title="Isocarbacyclin (page does not exist)">Isocarbacyclin</a></li> <li><a href="/w/index.php?title=MRE-269&action=edit&redlink=1" class="new" title="MRE-269 (page does not exist)">MRE-269</a></li> <li><a href="/w/index.php?title=NS-304&action=edit&redlink=1" class="new" title="NS-304 (page does not exist)">NS-304</a></li> <li><a href="/wiki/Prostacyclin" title="Prostacyclin">Prostacyclin (prostaglandin I<sub>2</sub>, epoprostenol)</a></li> <li><a href="/wiki/Prostaglandin_E1" title="Prostaglandin E1">Prostaglandin E<sub>1</sub> (alprostadil)</a></li> <li><a href="/w/index.php?title=Ralinepag&action=edit&redlink=1" class="new" title="Ralinepag (page does not exist)">Ralinepag</a></li> <li><a href="/wiki/Selexipag" title="Selexipag">Selexipag</a></li> <li><a href="/w/index.php?title=Taprostene&action=edit&redlink=1" class="new" title="Taprostene (page does not exist)">Taprostene</a></li> <li><a href="/w/index.php?title=TRA-418&action=edit&redlink=1" class="new" title="TRA-418 (page does not exist)">TRA-418</a></li> <li><a href="/wiki/Treprostinil" title="Treprostinil">Treprostinil</a></li></ul> <ul><li><b>Antagonists:</b> <a href="/w/index.php?title=RO1138452&action=edit&redlink=1" class="new" title="RO1138452 (page does not exist)">RO1138452</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Thromboxane_receptor" title="Thromboxane receptor"><abbr title="Thromboxane receptor">TP (TX<sub>A2</sub>)</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Thromboxane receptor</span></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b>Agonists:</b> <a href="/w/index.php?title=Carbocyclic_thromboxane_A2&action=edit&redlink=1" class="new" title="Carbocyclic thromboxane A2 (page does not exist)">Carbocyclic thromboxane A<sub>2</sub></a></li> <li><a href="/w/index.php?title=I-BOP&action=edit&redlink=1" class="new" title="I-BOP (page does not exist)">I-BOP</a></li> <li><a href="/wiki/Thromboxane_A2" title="Thromboxane A2">Thromboxane A<sub>2</sub></a></li> <li><a href="/wiki/U-46619" class="mw-redirect" title="U-46619">U-46619</a></li> <li><a href="/w/index.php?title=Vapiprost&action=edit&redlink=1" class="new" title="Vapiprost (page does not exist)">Vapiprost</a></li></ul> <ul><li><b>Antagonists:</b> <a href="/wiki/12-Hydroxyeicosatetraenoic_acid" title="12-Hydroxyeicosatetraenoic acid">12-HETE</a></li> <li><a href="/w/index.php?title=13-APA&action=edit&redlink=1" class="new" title="13-APA (page does not exist)">13-APA</a></li> <li><a href="/w/index.php?title=AA-2414&action=edit&redlink=1" class="new" title="AA-2414 (page does not exist)">AA-2414</a></li> <li><a href="/wiki/Argatroban" title="Argatroban">Argatroban</a></li> <li><a href="/w/index.php?title=Bay_U3405&action=edit&redlink=1" class="new" title="Bay U3405 (page does not exist)">Bay U3405</a></li> <li><a href="/w/index.php?title=BMS-180,291&action=edit&redlink=1" class="new" title="BMS-180,291 (page does not exist)">BMS-180,291</a></li> <li><a href="/w/index.php?title=Daltroban&action=edit&redlink=1" class="new" title="Daltroban (page does not exist)">Daltroban</a></li> <li><a href="/w/index.php?title=Domitroban&action=edit&redlink=1" class="new" title="Domitroban (page does not exist)">Domitroban</a></li> <li><a href="/w/index.php?title=EP-045&action=edit&redlink=1" class="new" title="EP-045 (page does not exist)">EP-045</a></li> <li><a href="/w/index.php?title=GR-32191&action=edit&redlink=1" class="new" title="GR-32191 (page does not exist)">GR-32191</a></li> <li><a href="/w/index.php?title=ICI-185282&action=edit&redlink=1" class="new" title="ICI-185282 (page does not exist)">ICI-185282</a></li> <li><a href="/w/index.php?title=ICI-192605&action=edit&redlink=1" class="new" title="ICI-192605 (page does not exist)">ICI-192605</a></li> <li><a href="/wiki/Ifetroban" title="Ifetroban">Ifetroban</a></li> <li><a href="/w/index.php?title=Imitrodast&action=edit&redlink=1" class="new" title="Imitrodast (page does not exist)">Imitrodast</a></li> <li><a href="/w/index.php?title=L-655240&action=edit&redlink=1" class="new" title="L-655240 (page does not exist)">L-655240</a></li> <li><a href="/w/index.php?title=L-670596&action=edit&redlink=1" class="new" title="L-670596 (page does not exist)">L-670596</a></li> <li><a href="/w/index.php?title=Linotroban&action=edit&redlink=1" class="new" title="Linotroban (page does not exist)">Linotroban</a></li> <li><a href="/w/index.php?title=Mipitroban&action=edit&redlink=1" class="new" title="Mipitroban (page does not exist)">Mipitroban</a></li> <li><a href="/w/index.php?title=ONO-3708&action=edit&redlink=1" class="new" title="ONO-3708 (page does not exist)">ONO-3708</a></li> <li><a href="/w/index.php?title=ONO-11120&action=edit&redlink=1" class="new" title="ONO-11120 (page does not exist)">ONO-11120</a></li> <li><a href="/wiki/Picotamide" title="Picotamide">Picotamide</a></li> <li><a href="/w/index.php?title=Pinane_thromboxane_A2&action=edit&redlink=1" class="new" title="Pinane thromboxane A2 (page does not exist)">Pinane thromboxane A<sub>2</sub></a></li> <li><a href="/wiki/Ramatroban" title="Ramatroban">Ramatroban</a></li> <li><a href="/w/index.php?title=Ridogrel&action=edit&redlink=1" class="new" title="Ridogrel (page does not exist)">Ridogrel</a></li> <li><a href="/w/index.php?title=S-145&action=edit&redlink=1" class="new" title="S-145 (page does not exist)">S-145</a></li> <li><a href="/w/index.php?title=Samixogrel&action=edit&redlink=1" class="new" title="Samixogrel (page does not exist)">Samixogrel</a></li> <li><a href="/wiki/Seratrodast" title="Seratrodast">Seratrodast</a></li> <li><a href="/w/index.php?title=SQ-28,668&action=edit&redlink=1" class="new" title="SQ-28,668 (page does not exist)">SQ-28,668</a></li> <li><a href="/w/index.php?title=SQ-29,548&action=edit&redlink=1" class="new" title="SQ-29,548 (page does not exist)">SQ-29,548</a></li> <li><a href="/w/index.php?title=Sulotroban&action=edit&redlink=1" class="new" title="Sulotroban (page does not exist)">Sulotroban</a></li> <li><a href="/wiki/Terbogrel" title="Terbogrel">Terbogrel</a></li> <li><a href="/wiki/Terutroban" title="Terutroban">Terutroban</a></li> <li><a href="/w/index.php?title=TRA-418&action=edit&redlink=1" class="new" title="TRA-418 (page does not exist)">TRA-418</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;">Unsorted</th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Arbaprostil&action=edit&redlink=1" class="new" title="Arbaprostil (page does not exist)">Arbaprostil</a></li> <li><a href="/w/index.php?title=Ataprost&action=edit&redlink=1" class="new" title="Ataprost (page does not exist)">Ataprost</a></li> <li><a href="/w/index.php?title=Ciprostene&action=edit&redlink=1" class="new" title="Ciprostene (page does not exist)">Ciprostene</a></li> <li><a href="/w/index.php?title=Clinprost&action=edit&redlink=1" class="new" title="Clinprost (page does not exist)">Clinprost</a></li> <li><a href="/w/index.php?title=Cobiprostone&action=edit&redlink=1" class="new" title="Cobiprostone (page does not exist)">Cobiprostone</a></li> <li><a href="/w/index.php?title=Delprostenate&action=edit&redlink=1" class="new" title="Delprostenate (page does not exist)">Delprostenate</a></li> <li><a href="/w/index.php?title=Deprostil&action=edit&redlink=1" class="new" title="Deprostil (page does not exist)">Deprostil</a></li> <li><a href="/w/index.php?title=Dimoxaprost&action=edit&redlink=1" class="new" title="Dimoxaprost (page does not exist)">Dimoxaprost</a></li> <li><a href="/w/index.php?title=Doxaprost&action=edit&redlink=1" class="new" title="Doxaprost (page does not exist)">Doxaprost</a></li> <li><a href="/w/index.php?title=Ecraprost&action=edit&redlink=1" class="new" title="Ecraprost (page does not exist)">Ecraprost</a></li> <li><a href="/w/index.php?title=Eganoprost&action=edit&redlink=1" class="new" title="Eganoprost (page does not exist)">Eganoprost</a></li> <li><a href="/w/index.php?title=Enisoprost&action=edit&redlink=1" class="new" title="Enisoprost (page does not exist)">Enisoprost</a></li> <li><a href="/w/index.php?title=Eptaloprost&action=edit&redlink=1" class="new" title="Eptaloprost (page does not exist)">Eptaloprost</a></li> <li><a href="/w/index.php?title=Esuberaprost&action=edit&redlink=1" class="new" title="Esuberaprost (page does not exist)">Esuberaprost</a></li> <li><a href="/w/index.php?title=Etiproston&action=edit&redlink=1" class="new" title="Etiproston (page does not exist)">Etiproston</a></li> <li><a href="/w/index.php?title=Fenprostalene&action=edit&redlink=1" class="new" title="Fenprostalene (page does not exist)">Fenprostalene</a></li> <li><a href="/w/index.php?title=Flunoprost&action=edit&redlink=1" class="new" title="Flunoprost (page does not exist)">Flunoprost</a></li> <li><a href="/w/index.php?title=Froxiprost&action=edit&redlink=1" class="new" title="Froxiprost (page does not exist)">Froxiprost</a></li> <li><a href="/w/index.php?title=Lanproston&action=edit&redlink=1" class="new" title="Lanproston (page does not exist)">Lanproston</a></li> <li><a href="/w/index.php?title=Limaprost&action=edit&redlink=1" class="new" title="Limaprost (page does not exist)">Limaprost</a></li> <li><a href="/w/index.php?title=Luprostiol&action=edit&redlink=1" class="new" title="Luprostiol (page does not exist)">Luprostiol</a></li> <li><a href="/w/index.php?title=Meteneprost&action=edit&redlink=1" class="new" title="Meteneprost (page does not exist)">Meteneprost</a></li> <li><a href="/w/index.php?title=Mexiprostil&action=edit&redlink=1" class="new" title="Mexiprostil (page does not exist)">Mexiprostil</a></li> <li><a href="/w/index.php?title=Naxaprostene&action=edit&redlink=1" class="new" title="Naxaprostene (page does not exist)">Naxaprostene</a></li> <li><a href="/w/index.php?title=Nileprost&action=edit&redlink=1" class="new" title="Nileprost (page does not exist)">Nileprost</a></li> <li><a href="/w/index.php?title=Nocloprost&action=edit&redlink=1" class="new" title="Nocloprost (page does not exist)">Nocloprost</a></li> <li><a href="/w/index.php?title=Ornoprostil&action=edit&redlink=1" class="new" title="Ornoprostil (page does not exist)">Ornoprostil</a></li> <li><a href="/w/index.php?title=Oxoprostol&action=edit&redlink=1" class="new" title="Oxoprostol (page does not exist)">Oxoprostol</a></li> <li><a href="/w/index.php?title=Penprostene&action=edit&redlink=1" class="new" title="Penprostene (page does not exist)">Penprostene</a></li> <li><a href="/w/index.php?title=Pimilprost&action=edit&redlink=1" class="new" title="Pimilprost (page does not exist)">Pimilprost</a></li> <li><a href="/w/index.php?title=Piriprost&action=edit&redlink=1" class="new" title="Piriprost (page does not exist)">Piriprost</a></li> <li><a href="/w/index.php?title=Posaraprost&action=edit&redlink=1" class="new" title="Posaraprost (page does not exist)">Posaraprost</a></li> <li><a href="/w/index.php?title=Prostalene&action=edit&redlink=1" class="new" title="Prostalene (page does not exist)">Prostalene</a></li> <li><a href="/w/index.php?title=Rioprostil&action=edit&redlink=1" class="new" title="Rioprostil (page does not exist)">Rioprostil</a></li> <li><a href="/w/index.php?title=Rivenprost&action=edit&redlink=1" class="new" title="Rivenprost (page does not exist)">Rivenprost</a></li> <li><a href="/w/index.php?title=Rosaprostol&action=edit&redlink=1" class="new" title="Rosaprostol (page does not exist)">Rosaprostol</a></li> <li><a href="/w/index.php?title=Spiriprostil&action=edit&redlink=1" class="new" title="Spiriprostil (page does not exist)">Spiriprostil</a></li> <li><a href="/w/index.php?title=Tiaprost&action=edit&redlink=1" class="new" title="Tiaprost (page does not exist)">Tiaprost</a></li> <li><a href="/w/index.php?title=Tilsuprost&action=edit&redlink=1" class="new" title="Tilsuprost (page does not exist)">Tilsuprost</a></li> <li><a href="/w/index.php?title=Tiprostanide&action=edit&redlink=1" class="new" title="Tiprostanide (page does not exist)">Tiprostanide</a></li> <li><a href="/w/index.php?title=Trimoprostil&action=edit&redlink=1" class="new" title="Trimoprostil (page does not exist)">Trimoprostil</a></li> <li><a href="/w/index.php?title=Viprostol&action=edit&redlink=1" class="new" title="Viprostol (page does not exist)">Viprostol</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Enzyme" title="Enzyme">Enzyme</a><br /><small>(<a href="/wiki/Enzyme_inhibitor" title="Enzyme inhibitor">inhibitors</a>)</small></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Cyclooxygenase" title="Cyclooxygenase"><abbr title="Cyclooxygenase">COX</abbr><br />(<abbr title="prostaglandin G/H synthase">PTGS</abbr>)</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><i>Salicylic acids:</i> <a href="/wiki/Aloxiprin" title="Aloxiprin">Aloxiprin</a></li> <li><a href="/wiki/Aspirin" title="Aspirin">Aspirin (acetylsalicylic acid)</a></li> <li><a href="/wiki/Benorilate" title="Benorilate">Benorilate (benorylate)</a></li> <li><a href="/wiki/Carbasalate_calcium" title="Carbasalate calcium">Carbasalate calcium</a></li> <li><a href="/wiki/Diflunisal" title="Diflunisal">Diflunisal</a></li> <li><a href="/wiki/Dipyrocetyl" title="Dipyrocetyl">Dipyrocetyl</a></li> <li><a href="/wiki/Ethenzamide" title="Ethenzamide">Ethenzamide</a></li> <li><a href="/wiki/Guacetisal" title="Guacetisal">Guacetisal</a></li> <li><a href="/wiki/Magnesium_salicylate" title="Magnesium salicylate">Magnesium salicylate</a></li> <li><a href="/wiki/Mesalazine" title="Mesalazine">Mesalazine (5-aminosalicylic acid)</a></li> <li><a href="/wiki/Methyl_salicylate" title="Methyl salicylate">Methyl salicylate</a></li> <li><a href="/w/index.php?title=Salacetamide&action=edit&redlink=1" class="new" title="Salacetamide (page does not exist)">Salacetamide</a></li> <li><a href="/wiki/Salicin" title="Salicin">Salicin</a></li> <li><a href="/wiki/Salicylamide" title="Salicylamide">Salicylamide</a></li> <li><a href="/wiki/Salicylate" class="mw-redirect" title="Salicylate">Salicylate (salicylic acid)</a></li> <li><a href="/wiki/Salsalate" title="Salsalate">Salsalate</a></li> <li><a href="/wiki/Sodium_salicylate" title="Sodium salicylate">Sodium salicylate</a></li> <li><a href="/wiki/Triflusal" title="Triflusal">Triflusal</a>; <i>Acetic acids:</i> <a href="/wiki/Aceclofenac" title="Aceclofenac">Aceclofenac</a></li> <li><a href="/wiki/Acemetacin" title="Acemetacin">Acemetacin</a></li> <li><a href="/w/index.php?title=Aclofenac&action=edit&redlink=1" class="new" title="Aclofenac (page does not exist)">Aclofenac</a></li> <li><a href="/wiki/Amfenac" title="Amfenac">Amfenac</a></li> <li><a href="/wiki/Alclofenac" title="Alclofenac">Alclofenac</a></li> <li><a href="/wiki/Bendazac" title="Bendazac">Bendazac</a></li> <li><a href="/wiki/Bromfenac" title="Bromfenac">Bromfenac</a></li> <li><a href="/wiki/Bufexamac" title="Bufexamac">Bufexamac</a></li> <li><a href="/wiki/Bumadizone" title="Bumadizone">Bumadizone</a></li> <li><a href="/w/index.php?title=Cinmetacin&action=edit&redlink=1" class="new" title="Cinmetacin (page does not exist)">Cinmetacin</a></li> <li><a href="/w/index.php?title=Clometacin&action=edit&redlink=1" class="new" title="Clometacin (page does not exist)">Clometacin</a></li> <li><a href="/wiki/Diclofenac" title="Diclofenac">Diclofenac</a></li> <li><a href="/wiki/Difenpiramide" title="Difenpiramide">Difenpiramide</a></li> <li><a href="/wiki/Etodolac" title="Etodolac">Etodolac</a></li> <li><a href="/wiki/Felbinac" title="Felbinac">Felbinac</a></li> <li><a href="/wiki/Fenclofenac" title="Fenclofenac">Fenclofenac</a></li> <li><a href="/wiki/Fentiazac" title="Fentiazac">Fentiazac</a></li> <li><a href="/wiki/Glucametacin" title="Glucametacin">Glucametacin</a></li> <li><a href="/wiki/Indometacin" title="Indometacin">Indometacin (indomethacin)</a></li> <li><a href="/wiki/Indometacin_farnesil" title="Indometacin farnesil">Indometacin farnesil</a></li> <li><a href="/wiki/Ketorolac" title="Ketorolac">Ketorolac</a></li> <li><a href="/wiki/Lonazolac" title="Lonazolac">Lonazolac</a></li> <li><a href="/wiki/Mofezolac" title="Mofezolac">Mofezolac</a></li> <li><a href="/wiki/Nabumetone" title="Nabumetone">Nabumetone</a></li> <li><a href="/wiki/Oxametacin" title="Oxametacin">Oxametacin</a></li> <li><a href="/w/index.php?title=Oxindanac&action=edit&redlink=1" class="new" title="Oxindanac (page does not exist)">Oxindanac</a></li> <li><a href="/wiki/Proglumetacin" title="Proglumetacin">Proglumetacin</a></li> <li><a href="/wiki/Sulindac" title="Sulindac">Sulindac</a></li> <li><a href="/w/index.php?title=Sulindac_sulfide&action=edit&redlink=1" class="new" title="Sulindac sulfide (page does not exist)">Sulindac sulfide</a></li> <li><a href="/wiki/Tolmetin" title="Tolmetin">Tolmetin</a></li> <li><a href="/w/index.php?title=Zidometacin&action=edit&redlink=1" class="new" title="Zidometacin (page does not exist)">Zidometacin</a></li> <li><a href="/wiki/Zomepirac" title="Zomepirac">Zomepirac</a>; <i>Propionic acids:</i> <a href="/wiki/Alminoprofen" title="Alminoprofen">Alminoprofen</a></li> <li><a href="/wiki/Benoxaprofen" title="Benoxaprofen">Benoxaprofen</a></li> <li><a href="/w/index.php?title=Bucloxic_acid&action=edit&redlink=1" class="new" title="Bucloxic acid (page does not exist)">Bucloxic acid (blucloxate)</a></li> <li><a href="/w/index.php?title=Butibufen&action=edit&redlink=1" class="new" title="Butibufen (page does not exist)">Butibufen</a></li> <li><a href="/wiki/Carprofen" title="Carprofen">Carprofen</a></li> <li><a href="/wiki/Dexibuprofen" title="Dexibuprofen">Dexibuprofen</a></li> <li><a href="/w/index.php?title=Dexindoprofen&action=edit&redlink=1" class="new" title="Dexindoprofen (page does not exist)">Dexindoprofen</a></li> <li><a href="/wiki/Dexketoprofen" title="Dexketoprofen">Dexketoprofen</a></li> <li><a href="/wiki/Fenbufen" title="Fenbufen">Fenbufen</a></li> <li><a href="/wiki/Fenoprofen" title="Fenoprofen">Fenoprofen</a></li> <li><a href="/wiki/Flunoxaprofen" title="Flunoxaprofen">Flunoxaprofen</a></li> <li><a href="/wiki/Flurbiprofen" title="Flurbiprofen">Flurbiprofen</a></li> <li><a href="/wiki/Ibuprofen" title="Ibuprofen">Ibuprofen</a></li> <li><a href="/wiki/Ibuproxam" title="Ibuproxam">Ibuproxam</a></li> <li><a href="/wiki/Indoprofen" title="Indoprofen">Indoprofen</a></li> <li><a href="/wiki/Ketoprofen" title="Ketoprofen">Ketoprofen</a></li> <li><a href="/wiki/Loxoprofen" title="Loxoprofen">Loxoprofen</a></li> <li><a href="/wiki/Miroprofen" title="Miroprofen">Miroprofen</a></li> <li><a href="/wiki/Naproxen" title="Naproxen">Naproxen</a></li> <li><a href="/wiki/Naproxcinod" title="Naproxcinod">Naproxcinod</a></li> <li><a href="/wiki/Oxaprozin" title="Oxaprozin">Oxaprozin</a></li> <li><a href="/wiki/Pirprofen" title="Pirprofen">Pirprofen</a></li> <li><a href="/wiki/Pranoprofen" title="Pranoprofen">Pranoprofen</a></li> <li><a href="/wiki/Suprofen" title="Suprofen">Suprofen</a></li> <li><a href="/wiki/Tarenflurbil" title="Tarenflurbil">Tarenflurbil</a></li> <li><a href="/wiki/Tepoxalin" title="Tepoxalin">Tepoxalin</a></li> <li><a href="/wiki/Tiaprofenic_acid" title="Tiaprofenic acid">Tiaprofenic acid (tiaprofenate)</a></li> <li><a href="/wiki/Vedaprofen" title="Vedaprofen">Vedaprofen</a>; <i>Anthranilic acids (fenamic acids):</i> <a href="/wiki/Etofenamate" title="Etofenamate">Etofenamic acid (etofenamate)</a></li> <li><a href="/w/index.php?title=Floctafenic_acid&action=edit&redlink=1" class="new" title="Floctafenic acid (page does not exist)">Floctafenic acid (floctafenate)</a></li> <li><a href="/wiki/Flufenamic_acid" title="Flufenamic acid">Flufenamic acid (flufenamate)</a></li> <li><a href="/wiki/Meclofenamic_acid" title="Meclofenamic acid">Meclofenamic acid (meclofenamate)</a></li> <li><a href="/wiki/Mefenamic_acid" title="Mefenamic acid">Mefenamic acid (mefenamate)</a></li> <li><a href="/wiki/Morniflumate" title="Morniflumate">Morniflumic acid (morniflumate)</a></li> <li><a href="/wiki/Niflumic_acid" title="Niflumic acid">Niflumic acid (niflumate)</a></li> <li><a href="/w/index.php?title=Talinflumic_acid&action=edit&redlink=1" class="new" title="Talinflumic acid (page does not exist)">Talinflumic acid (talinflumate)</a></li> <li><a href="/wiki/Tolfenamic_acid" title="Tolfenamic acid">Tolfenamic acid (tolfenamate)</a>; <i>Pyrazolones:</i> <a href="/wiki/Azapropazone" title="Azapropazone">Azapropazone</a></li> <li><a href="/wiki/Dipyrone" class="mw-redirect" title="Dipyrone">Dipyrone</a></li> <li><a href="/wiki/Isopyrin" class="mw-redirect" title="Isopyrin">Isopyrin</a></li> <li><a href="/wiki/Oxyphenbutazone" title="Oxyphenbutazone">Oxyphenbutazone</a></li> <li><a href="/wiki/Phenylbutazone" title="Phenylbutazone">Phenylbutazone</a>; <i>Enolic acids (oxicams):</i> <a href="/wiki/Ampiroxicam" title="Ampiroxicam">Ampiroxicam</a></li> <li><a href="/wiki/Droxicam" title="Droxicam">Droxicam</a></li> <li><a href="/w/index.php?title=Enolicam&action=edit&redlink=1" class="new" title="Enolicam (page does not exist)">Enolicam</a></li> <li><a href="/wiki/Isoxicam" title="Isoxicam">Isoxicam</a></li> <li><a href="/wiki/Lornoxicam" title="Lornoxicam">Lornoxicam</a></li> <li><a href="/wiki/Meloxicam" title="Meloxicam">Meloxicam</a></li> <li><a href="/wiki/Piroxicam" title="Piroxicam">Piroxicam</a></li> <li><a href="/wiki/Tenoxicam" title="Tenoxicam">Tenoxicam</a>; <i>4-Aminoquinolines:</i> <a href="/wiki/Antrafenine" title="Antrafenine">Antrafenine</a></li> <li><a href="/wiki/Floctafenine" title="Floctafenine">Floctafenine</a></li> <li><a href="/wiki/Glafenine" title="Glafenine">Glafenine</a>; <i>Quinazolines:</i> <a href="/wiki/Fluproquazone" title="Fluproquazone">Fluproquazone</a></li> <li><a href="/wiki/Proquazone" title="Proquazone">Proquazone</a>; <i>Aminonicotinic acids:</i> <a href="/w/index.php?title=Clonixeril&action=edit&redlink=1" class="new" title="Clonixeril (page does not exist)">Clonixeril</a></li> <li><a href="/wiki/Clonixin" title="Clonixin">Clonixin</a></li> <li><a href="/wiki/Flunixin" title="Flunixin">Flunixin</a>; <i>Sulfonanilides:</i> <a href="/w/index.php?title=Flosulide&action=edit&redlink=1" class="new" title="Flosulide (page does not exist)">Flosulide</a></li> <li><a href="/wiki/Nimesulide" title="Nimesulide">Nimesulide</a>; <i>Aminophenols (anilines):</i> <a href="/wiki/Acetanilide" title="Acetanilide">Acetanilide</a></li> <li><a href="/wiki/AM404" title="AM404">AM-404 (N-arachidonoylaminophenol)</a></li> <li><a href="/wiki/Bucetin" title="Bucetin">Bucetin</a></li> <li><a href="/wiki/Paracetamol" title="Paracetamol">Paracetamol (acetaminophen)</a></li> <li><a href="/w/index.php?title=Parapropamol&action=edit&redlink=1" class="new" title="Parapropamol (page does not exist)">Parapropamol</a></li> <li><a href="/wiki/Phenacetin" title="Phenacetin">Phenacetin</a></li> <li><a href="/wiki/Propacetamol" title="Propacetamol">Propacetamol</a>; <i>Selective COX-2 inhibitors (coxibs):</i> <a href="/wiki/Apricoxib" title="Apricoxib">Apricoxib</a></li> <li><a href="/wiki/Celecoxib" title="Celecoxib">Celecoxib</a></li> <li><a href="/wiki/Cimicoxib" title="Cimicoxib">Cimicoxib</a></li> <li><a href="/wiki/Deracoxib" title="Deracoxib">Deracoxib</a></li> <li><a href="/wiki/Etoricoxib" title="Etoricoxib">Etoricoxib</a></li> <li><a href="/wiki/Firocoxib" title="Firocoxib">Firocoxib</a></li> <li><a href="/wiki/Lumiracoxib" title="Lumiracoxib">Lumiracoxib</a></li> <li><a href="/wiki/Mavacoxib" title="Mavacoxib">Mavacoxib</a></li> <li><a href="/wiki/Parecoxib" title="Parecoxib">Parecoxib</a></li> <li><a href="/wiki/Polmacoxib" title="Polmacoxib">Polmacoxib</a></li> <li><a href="/wiki/Robenacoxib" title="Robenacoxib">Robenacoxib</a></li> <li><a href="/wiki/Rofecoxib" title="Rofecoxib">Rofecoxib</a></li> <li><a href="/wiki/Tilmacoxib" title="Tilmacoxib">Tilmacoxib</a></li> <li><a href="/wiki/Valdecoxib" title="Valdecoxib">Valdecoxib</a>; <i>Others/unsorted:</i> <a href="/wiki/Anitrazafen" title="Anitrazafen">Anitrazafen</a></li> <li><a href="/w/index.php?title=Clobuzarit&action=edit&redlink=1" class="new" title="Clobuzarit (page does not exist)">Clobuzarit</a></li> <li><a href="/wiki/Curcumin" title="Curcumin">Curcumin</a></li> <li><a href="/w/index.php?title=DuP-697&action=edit&redlink=1" class="new" title="DuP-697 (page does not exist)">DuP-697</a></li> <li><a href="/w/index.php?title=FK-3311&action=edit&redlink=1" class="new" title="FK-3311 (page does not exist)">FK-3311</a></li> <li><a href="/wiki/Flumizole" title="Flumizole">Flumizole</a></li> <li><a href="/w/index.php?title=FR-122047&action=edit&redlink=1" class="new" title="FR-122047 (page does not exist)">FR-122047</a></li> <li><a href="/wiki/Glimepiride" title="Glimepiride">Glimepiride</a></li> <li><a href="/wiki/Hyperforin" title="Hyperforin">Hyperforin</a></li> <li><a href="/w/index.php?title=Itazigrel&action=edit&redlink=1" class="new" title="Itazigrel (page does not exist)">Itazigrel</a></li> <li><a href="/w/index.php?title=L-655240&action=edit&redlink=1" class="new" title="L-655240 (page does not exist)">L-655240</a></li> <li><a href="/w/index.php?title=L-670596&action=edit&redlink=1" class="new" title="L-670596 (page does not exist)">L-670596</a></li> <li><a href="/wiki/Licofelone" title="Licofelone">Licofelone</a></li> <li><a href="/wiki/Menatetrenone" title="Menatetrenone">Menatetrenone (vitamin K<sub>2</sub>)</a></li> <li><a href="/w/index.php?title=NCX-466&action=edit&redlink=1" class="new" title="NCX-466 (page does not exist)">NCX-466</a></li> <li><a href="/w/index.php?title=NCX-4040&action=edit&redlink=1" class="new" title="NCX-4040 (page does not exist)">NCX-4040</a></li> <li><a href="/wiki/NS-398" title="NS-398">NS-398</a></li> <li><a href="/wiki/Pamicogrel" title="Pamicogrel">Pamicogrel</a></li> <li><a href="/wiki/Resveratrol" title="Resveratrol">Resveratrol</a></li> <li><a href="/w/index.php?title=Romazarit&action=edit&redlink=1" class="new" title="Romazarit (page does not exist)">Romazarit</a></li> <li><a href="/wiki/Rosmarinic_acid" title="Rosmarinic acid">Rosmarinic acid</a></li> <li><a href="/wiki/Rutecarpine" title="Rutecarpine">Rutecarpine</a></li> <li><a href="/w/index.php?title=Satigrel&action=edit&redlink=1" class="new" title="Satigrel (page does not exist)">Satigrel</a></li> <li><a href="/w/index.php?title=SC-236&action=edit&redlink=1" class="new" title="SC-236 (page does not exist)">SC-236</a></li> <li><a href="/w/index.php?title=SC-560&action=edit&redlink=1" class="new" title="SC-560 (page does not exist)">SC-560</a></li> <li><a href="/w/index.php?title=SC-58125&action=edit&redlink=1" class="new" title="SC-58125 (page does not exist)">SC-58125</a></li> <li><a href="/wiki/Tenidap" title="Tenidap">Tenidap</a></li> <li><a href="/w/index.php?title=Tiflamizole&action=edit&redlink=1" class="new" title="Tiflamizole (page does not exist)">Tiflamizole</a></li> <li><a href="/w/index.php?title=Timegadine&action=edit&redlink=1" class="new" title="Timegadine (page does not exist)">Timegadine</a></li> <li><a href="/w/index.php?title=Trifenagrel&action=edit&redlink=1" class="new" title="Trifenagrel (page does not exist)">Trifenagrel</a></li> <li><a href="/w/index.php?title=Tropesin&action=edit&redlink=1" class="new" title="Tropesin (page does not exist)">Tropesin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Prostaglandin_D_synthase" class="mw-redirect" title="Prostaglandin D synthase"><abbr title="Prostaglandin D synthase">PGD<sub>2</sub>S</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Prostaglandin D synthase</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Retinoid" title="Retinoid">Retinoids</a></li> <li><a href="/wiki/Selenium" title="Selenium">Selenium</a> (<a href="/wiki/Selenium_tetrachloride" title="Selenium tetrachloride">selenium tetrachloride</a>, <a href="/wiki/Sodium_selenite" title="Sodium selenite">sodium selenite</a>, <a href="/wiki/Selenium_disulfide" title="Selenium disulfide">selenium disulfide</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Prostaglandin_E_synthase" title="Prostaglandin E synthase"><abbr title="Prostaglandin E synthase">PGES</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Prostaglandin E synthase</span></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"><a href="/w/index.php?title=HQL-79&action=edit&redlink=1" class="new" title="HQL-79 (page does not exist)">HQL-79</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Prostaglandin_F_synthase" title="Prostaglandin F synthase"><abbr title="Prostaglandin F synthase">PGFS</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Prostaglandin F synthase</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"><a href="/wiki/Bimatoprost" title="Bimatoprost">Bimatoprost</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Prostacyclin_synthase" title="Prostacyclin synthase"><abbr title="Prostacyclin synthase">PGI<sub>2</sub>S</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Prostacyclin synthase</span></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"><a href="/wiki/Tranylcypromine" title="Tranylcypromine">Tranylcypromine</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Thromboxane_A_synthase" class="mw-redirect" title="Thromboxane A synthase"><abbr title="Thromboxane A synthase">TXAS</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Thromboxane A synthase</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Camonagrel&action=edit&redlink=1" class="new" title="Camonagrel (page does not exist)">Camonagrel</a></li> <li><a href="/w/index.php?title=Dazmegrel&action=edit&redlink=1" class="new" title="Dazmegrel (page does not exist)">Dazmegrel</a></li> <li><a href="/wiki/Dazoxiben" title="Dazoxiben">Dazoxiben</a></li> <li><a href="/wiki/Furegrelate" title="Furegrelate">Furegrelate</a></li> <li><a href="/w/index.php?title=Isbogrel&action=edit&redlink=1" class="new" title="Isbogrel (page does not exist)">Isbogrel</a></li> <li><a href="/w/index.php?title=Midazogrel&action=edit&redlink=1" class="new" title="Midazogrel (page does not exist)">Midazogrel</a></li> <li><a href="/w/index.php?title=Nafagrel&action=edit&redlink=1" class="new" title="Nafagrel (page does not exist)">Nafagrel</a></li> <li><a href="/w/index.php?title=Nicogrelate&action=edit&redlink=1" class="new" title="Nicogrelate (page does not exist)">Nicogrelate</a></li> <li><a href="/wiki/Ozagrel" title="Ozagrel">Ozagrel</a></li> <li><a href="/wiki/Picotamide" title="Picotamide">Picotamide</a></li> <li><a href="/w/index.php?title=Pirmagrel&action=edit&redlink=1" class="new" title="Pirmagrel (page does not exist)">Pirmagrel</a></li> <li><a href="/w/index.php?title=Ridogrel&action=edit&redlink=1" class="new" title="Ridogrel (page does not exist)">Ridogrel</a></li> <li><a href="/w/index.php?title=Rolafagrel&action=edit&redlink=1" class="new" title="Rolafagrel (page does not exist)">Rolafagrel</a></li> <li><a href="/w/index.php?title=Samixogrel&action=edit&redlink=1" class="new" title="Samixogrel (page does not exist)">Samixogrel</a></li> <li><a href="/wiki/Terbogrel" title="Terbogrel">Terbogrel</a></li> <li><a href="/w/index.php?title=U63557A&action=edit&redlink=1" class="new" title="U63557A (page does not exist)">U63557A</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;">Others</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><b>Precursors:</b> <a href="/wiki/Linoleic_acid" title="Linoleic acid">Linoleic acid</a></li> <li><a href="/wiki/Gamma-Linolenic_acid" class="mw-redirect" title="Gamma-Linolenic acid">γ-Linolenic acid (gamolenic acid)</a></li> <li><a href="/wiki/Dihomo-%CE%B3-linolenic_acid" title="Dihomo-γ-linolenic acid">Dihomo-γ-linolenic acid</a></li> <li><a href="/wiki/Diglyceride" title="Diglyceride">Diacylglycerol</a></li> <li><a href="/wiki/Arachidonic_acid" title="Arachidonic acid">Arachidonic acid</a></li> <li><a href="/wiki/Prostaglandin_G2" title="Prostaglandin G2">Prostaglandin G<sub>2</sub></a></li> <li><a href="/wiki/Prostaglandin_H2" title="Prostaglandin H2">Prostaglandin H<sub>2</sub></a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <dl><dt>See also</dt> <dd><i><a href="/wiki/Template:Receptor_modulators" title="Template:Receptor modulators">Receptor/signaling modulators</a></i></dd> <dd><i><a href="/wiki/Template:Leukotriene_signaling_modulators" title="Template:Leukotriene signaling modulators">Leukotriene signaling modulators</a></i></dd></dl> 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