Webinar Recording - Accelerate Protein Screening by Sequencing Protein Barcodes on Platinum

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id="hs_cos_wrapper_widget_1712156805350" class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style="" data-hs-cos-general-type="widget" data-hs-cos-type="module"> <div class="resource-single"> <div class="header"> <div class="container-wrapper"> <div class="wide-container header-container p-y-30"> <div class="header-content flex-3"> <div class="heading-smallcaps color-white"> Clinical Diagnostics | Webinars </div> <h1 class="heading color-white"> Accelerate Protein Screening by Sequencing Protein Barcodes on Platinum® </h1> <div class="byline color-white i"> 28 June 2024 </div> </div> <div class="header-graphic flex-2"> <img src="https://oxfordglobal.com/hubfs/Website/Images/Resources/Omics/Accelerate%20Protein%20Screening%20by%20Sequencing%20Protein%20Barcodes%20on%20Platinum%20-%20Content%20Portal%20Image.jpg" class="header-graphic-image"> </div> </div> </div> </div> <div class="container-wrapper abstract-banner-color"> <div class="wide-container flex g-20 flex-column-sm"> <div class="color-white text-110 s-b flex-3 flex flex-align-center"> On-demand webinar presented by Joel McDade, PhD, Sr. Commercial Business Development Manager, Quantum-Si and Bonnie Lun, PhD, Field Application Scientist. Sponsored by Quantum Si. </div> <div class="color-white heading-smallcaps center flex-2 flex g-10 flex-align-center flex-justify-center"> <a href="https://www.quantum-si.com/"> <div class="sponsor-logo flex-1"> <img src="https://oxfordglobal.com/hubfs/Sponsor%20Logos/Quantum%20Si.jpg"> </div> </a> </div> </div> </div> <div class="container-wrapper"> <div class="wide-container"> <div class="content"> <div class="content-body text-gap"> <p>Screening protein variants of interest is an essential step when studying mechanism of disease or developing novel biotherapeutics. Current screening methods require either back-to-back design-build-test cycles or large arrayed screens using automation, which can lead to lengthy assay timelines, technical challenges, unwanted variability and unnecessary cost. Furthermore, traditional phage-display or yeast-display methods may not be optimal for certain proteins of interest due to size or structure of the proteins. Pooled screening can circumvent many of these limitations, but de facto standard DNA-based barcodes cannot be used to screen for certain phenotypes. As such, there is significant interest in the use of protein barcodes to screen protein variants.</p> <p>Quantum-Si has recently developed a scalable method for using protein barcodes to identify specific proteins with desirable characteristics by sequencing highly distinguishable peptides on the benchtop protein sequencing platform, Platinum. Briefly, unique peptides are associated with each protein and cleaved from the protein after enrichment and selection for the proteins of interest. The peptides are then functionalized and immobilized on a semiconductor chip and sequenced by Platinum with single amino acid resolution.</p> <p>This webinar reviews the current state of protein screening approaches, introduce the Platinum protein sequencing workflow and highlight how this technology can simplify and accelerate a variety of screening workflows through the use of highly distinguishable protein barcodes.</p> <p><strong>Key Learning Points/Takeaways:</strong></p> <ol> <li> <p>Review of Quantum-Si’s Platinum protein sequencing technology</p> </li> <li> <p>Introduction to protein barcoding on Platinum</p> </li> <li> <p>How protein barcoding simplifies and accelerates protein screening across a wide variety of applications</p> </li> </ol> <div class="m-y-20 drop-shadow-subtle"> <div class="hs-video-widget" data-hsv-embed-id="8ad897d4-3461-4514-bb53-296c440bcb57"> <div class="hs-video-container" style="max-width: 1920px; margin: 0 auto;"> <div class="hs-video-wrapper" style="position: relative; height: 0; padding-bottom: 56.25%"> <iframe data-hsv-src="https://play.hubspotvideo.com/v/8696823/id/170944018347" referrerpolicy="origin" sandbox="allow-forms allow-scripts allow-same-origin allow-popups" allow="autoplay; fullscreen;" style="position: absolute !important; width: 100% !important; height: 100% !important; left: 0; top: 0; border: 0 none; pointer-events: initial" title="HubSpot Video" loading="lazy" data-hsv-id="170944018347" data-hsv-width="1920" data-hsv-height="1080" data-hsv-autoplay="false" data-hsv-loop="false" data-hsv-muted="false" data-hsv-hidden-controls="false" data-hsv-full-width="false"></iframe> </div> </div> </div> </div> <div class="content-body-footer"> <div class="author-info text-no-gap"> <div class="author-about"> <h3> Speaker Biographies </h3> <div> <div> <div> <p><strong>Dr. Joel McDade, PhD,</strong><span> </span>is Senior Commercial Business Development Manager at Quantum-Si. Joel has a background in cell biology, human physiology & human genetics and has authored in peer-reviewed publications. Dr. McDade obtained a PhD in Molecular and Integrative Physiology from the University of Michigan and a post-doc from Harvard Medical School. He has significant experience in molecular biology, including CRISPR/Cas9, including pooled CRISPR screening and common proteomics workflows. At Quantum-Si, Dr. McDade works directly with interested scientists to explore how next-generation protein sequencing technology can advance their research. </p> <p><strong>Dr. Cheng man (Bonnie) Lun, PhD,</strong><span> </span>is a field application scientist providing customer technical and application support at Quantum-Si. She has over a decade of bench scientist experience in immunology and virology related research and authored in peer-reviewed publications. Lun graduated from University of New Mexico, earned her doctorate at George Washington University, and did her postdoctoral training at National Cancer Institute. She has experience in parasitology, immunology, virology, molecular biology and proteomics. At Quantum-Si, she works closely with academia, biotech, and pharma to advance their research using the next-generation protein sequencing technology. </p> </div> </div> </div> </div> </div> </div> </div> <div class="content-sidebar"> </div> </div> </div> </div> </div> <div class="newsletter-cta"> <h2 class="heading">Subscribe to our newsletter</h2> <div class="message"> Sign up for our monthly Newsletter to keep up with all things Precision Medicine </div> <div class="button-wrapper"> <a href="#" class="button hs-cta-trigger-button hs-cta-trigger-button-177053686110">Newsletter Sign-Up</a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </main> <div data-global-resource-path="git/og-stage/templates/partials/footer.html"><footer class="website-footer flex flex-column g-20"> <div class="footer-columns"> <div class="footer-column"> <a href="https://oxfordglobal.com" class="site-logo-link"> <img src="https://oxfordglobal.com/wp-content/uploads/2023/03/Oxford-Global-Logo-Stacked-Websize.png" class="site-logo"> </a> </div> <div class="footer-column"> <h3>Brands</h3> <ul> <li> <a href="/precision-medicine/">Precision Medicine</a> </li> <li> <a href="/discovery-development/">Discovery & Development</a> </li> <li> <a href="/nextgen-biomed/">NextGen Biomed</a> </li> </ul> </div> <div class="footer-column"> <h3>Services</h3> <ul> <li> <a href="https://oxfordglobal.com/in-person-services/"> In-Person Services </a> </li> <li> <a href="https://oxfordglobal.com/digital-marketing-services/"> Digital Marketing Services </a> </li> </ul> <h3>Upcoming Events</h3> <ul> <li> <a href="https://oxfordglobal.com/calendar/"> Event Calendar </a> </li> </ul> </div> <div class="footer-column"> <h3>Company</h3> <ul> <li class="elementor-icon-list-item"> <a href="https://oxfordglobal.com/about-us/"> About </a> </li> <li class="elementor-icon-list-item"> <a href="https://oxfordglobal.com/vacancies/"> Vacancies </a> </li> <li class="elementor-icon-list-item"> <a href="https://oxfordglobal.com/csr-policy/"> CSR Policy </a> </li> <li class="elementor-icon-list-item"> <a href="javascript:postMessage({type:'HS_DISPLAY_CALL_TO_ACTION',id:130207947529});"> Contact </a> </li> </ul> </div> <div class="footer-column"> <p> <a href="tel:+441865248455">+44 1865 248 455</a><br> <a href="mailto:help@oxfordglobal.com">help@oxfordglobal.com</a> </p> <p> <strong>Our UK Address:</strong><br> Godstow Court<br> Minns Business Park<br> Botley<br> Oxford, OX2 0JB </p> <p> <strong>Our US Address:</strong><br> 100 Cambridge Street<br> 14th Floor<br> Boston<br> MA 02114 </p> </div> </div> <div class="footer-bottom grid g-20"> <div class="span8 span12-sm span12-md flex flex-column g-10"> <div class="copyright"> © Oxford Global Marketing Ltd. 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