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<!DOCTYPE html> <html xmlns="http://www.w3.org/1999/xhtml" lang="en-US" prefix="bioschema: https://bioschemas.org/"> <head> <meta http-equiv="Content-Type" content="text/html;charset=iso-8859-1">  <meta name="viewport" content="width=device-width, initial-scale=1.0">  <script type="application/ld+json"> { "@context": [ "https://schema.org/" ], "@type": "Organization", "url": "https://enzyme.expasy.org", "name": "ENZYME", "logo": "https://enzyme.expasy.org/images/expasy_logos/Expasy_logo_base_addon.svg", "memberof": { "@type": "NGO", "name": "SIB Swiss Institute of Bioinformatics", "url": "https://sib.swiss/" }, "parentOrganization": { "@type": "Organization", "name": "Expasy", "url": "https://www.expasy.org/" } } </script>  <script type="text/javascript" src="/js/jquery.min.js"></script> <script type="text/javascript" src="/js/main.js"></script> <link rel="stylesheet" href="/css/normalize.css?v=1.1" type="text/css" media="screen" charset="utf-8"> <link rel="stylesheet" href="/css/expasy_geneva.css?v=1.1" type="text/css" charset="utf-8">  <title>ENZYME search by enzyme class</title> </head> <body class="enzyme" typeof="schema:DataSet">  <header class="header-grid"> <div class="header-elmt"> <img alt="Expasy logo" src="/images/expasy_logos/Expasy_logo_base_addon.svg"> </div> <h4 class="header-elmt"><a href="https://enzyme.expasy.org">ENZYME</a></h4> <nav class="header-elmt with-title" itemscope itemtype="http://www.schema.org/SiteNavigationElement"> <ul class="menu-6-items"> <li> <img src="/images/icons/home.svg" alt="home"> <a itemprop="url" href="/index.html">Home</a> </li> <li class="with-submenu"> <img src="/images/icons/tool.svg" alt="tool"> <a itemprop="url" href="/cgi-bin/enzyme/enzyme-search-cl?1">Browse</a> <ul> <li><a itemprop="url" href="/cgi-bin/enzyme/enzyme-search-cl?1">by classes</a></li> <li><a itemprop="url" href="/cgi-bin/enzyme/enzyme-search-cl?2">by subclasses</a></li> <li><a itemprop="url" href="/cgi-bin/enzyme/enzyme-search-cl?3">by subsubclasses</a></li> </ul> </li> <li class="with-submenu"> <img src="/images/icons/browse.svg" alt="browse"> <a itemprop="url" href="/enzyme-search-ec.html">Search</a> <ul> <li><a itemprop="url" href="/enzyme-search-ec.html">by EC number</a></li> <li><a itemprop="url" href="/enzyme-byname.html">by name</a></li> <li><a itemprop="url" href="/enzyme-bycompound.html">by chemical compound</a></li> <li><a itemprop="url" href="/enzyme-bycomment.html">by comment</a></li> </ul> </li> <li class="with-submenu"> <img src="/images/icons/documents.svg" alt="documents"> <a itemprop="url" href="https://ftp.expasy.org/databases/enzyme/">Documentation</a> <ul> <li><a itemprop="url" href="https://ftp.expasy.org/databases/enzyme/enzuser.txt">User Manual</a></li> <li><a itemprop="url" href="https://ftp.expasy.org/databases/enzyme/enzyme.get">How to obtain ENZYME</a></li> </ul> </li> <li> <img src="/images/icons/download.svg" alt="download"> <a itemprop="url" href="https://ftp.expasy.org/databases/enzyme/">Downloads</a> </li> <li> <img src="/images/icons/contact.svg" alt="contact"> <a itemprop="url" href="/contact">Contact</a> </li> </ul> </nav> </header>  <main class="main-grid">  <div class="main-elmt"> <h1>ENZYME - Browse Classes and Subclasses</h1> The following list contains the definitions of enzyme classes, subclasses and sub-subclasses. If you click on one of the following lines, you will get a list of all enzymes in the corresponding classes, with the possibility to obtain a list of all corresponding UniProtKB/Swiss-Prot entries. A single file containing all enzyme entries can be found at <a property="schema:url" href="https://ftp.expasy.org/databases/enzyme/enzyme.dat">https://ftp.expasy.org/databases/enzyme/enzyme.dat</a>. View options:<UL> <LI><A HREF="/cgi-bin/enzyme/enzyme-search-cl?3">display classes, subclasses and subsubclasses</A> <LI><A HREF="/cgi-bin/enzyme/enzyme-search-cl?1">display classes only</A> </UL> <PRE> <a property="schema:url" HREF = "/EC/1.-.-.-">1. -. -.-</A> Oxidoreductases. <a property="schema:url" HREF = "/EC/1.1.-.-">1. 1. -.-</A> Acting on the CH-OH group of donors. <a property="schema:url" HREF = "/EC/1.2.-.-">1. 2. -.-</A> Acting on the aldehyde or oxo group of donors. <a property="schema:url" HREF = "/EC/1.3.-.-">1. 3. -.-</A> Acting on the CH-CH group of donors. <a property="schema:url" HREF = "/EC/1.4.-.-">1. 4. -.-</A> Acting on the CH-NH2 group of donors. <a property="schema:url" HREF = "/EC/1.5.-.-">1. 5. -.-</A> Acting on the CH-NH group of donors. <a property="schema:url" HREF = "/EC/1.6.-.-">1. 6. -.-</A> Acting on NADH or NADPH. <a property="schema:url" HREF = "/EC/1.7.-.-">1. 7. -.-</A> Acting on other nitrogenous compounds as donors. <a property="schema:url" HREF = "/EC/1.8.-.-">1. 8. -.-</A> Acting on a sulfur group of donors. <a property="schema:url" HREF = "/EC/1.9.-.-">1. 9. -.-</A> Acting on a heme group of donors. <a property="schema:url" HREF = "/EC/1.10.-.-">1.10. -.-</A> Acting on diphenols and related substances as donors. <a property="schema:url" HREF = "/EC/1.11.-.-">1.11. -.-</A> Acting on a peroxide as acceptor. <a property="schema:url" HREF = "/EC/1.12.-.-">1.12. -.-</A> Acting on hydrogen as donors. <a property="schema:url" HREF = "/EC/1.13.-.-">1.13. -.-</A> Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. <a property="schema:url" HREF = "/EC/1.14.-.-">1.14. -.-</A> Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. <a property="schema:url" HREF = "/EC/1.15.-.-">1.15. -.-</A> Acting on superoxide as acceptor. <a property="schema:url" HREF = "/EC/1.16.-.-">1.16. -.-</A> Oxidizing metal ions. <a property="schema:url" HREF = "/EC/1.17.-.-">1.17. -.-</A> Acting on CH or CH2 groups. <a property="schema:url" HREF = "/EC/1.18.-.-">1.18. -.-</A> Acting on iron-sulfur proteins as donors. <a property="schema:url" HREF = "/EC/1.19.-.-">1.19. -.-</A> Acting on reduced flavodoxin as donor. <a property="schema:url" HREF = "/EC/1.20.-.-">1.20. -.-</A> Acting on phosphorus or arsenic in donors. <a property="schema:url" HREF = "/EC/1.21.-.-">1.21. -.-</A> Catalyzing the reaction X-H + Y-H = 'X-Y'. <a property="schema:url" HREF = "/EC/1.22.-.-">1.22. -.-</A> Acting on halogen in donors. <a property="schema:url" HREF = "/EC/1.23.-.-">1.23. -.-</A> Reducing C-O-C group as acceptor. <a property="schema:url" HREF = "/EC/1.97.-.-">1.97. -.-</A> Other oxidoreductases. <a property="schema:url" HREF = "/EC/1.98.-.-">1.98. -.-</A> Enzymes using H2 as reductant. <a property="schema:url" HREF = "/EC/1.99.-.-">1.99. -.-</A> Other enzymes using O2 as oxidant. <a property="schema:url" HREF = "/EC/2.-.-.-">2. -. -.-</A> Transferases. <a property="schema:url" HREF = "/EC/2.1.-.-">2. 1. -.-</A> Transferring one-carbon groups. <a property="schema:url" HREF = "/EC/2.2.-.-">2. 2. -.-</A> Transferring aldehyde or ketonic groups. <a property="schema:url" HREF = "/EC/2.3.-.-">2. 3. -.-</A> Acyltransferases. <a property="schema:url" HREF = "/EC/2.4.-.-">2. 4. -.-</A> Glycosyltransferases. <a property="schema:url" HREF = "/EC/2.5.-.-">2. 5. -.-</A> Transferring alkyl or aryl groups, other than methyl groups. <a property="schema:url" HREF = "/EC/2.6.-.-">2. 6. -.-</A> Transferring nitrogenous groups. <a property="schema:url" HREF = "/EC/2.7.-.-">2. 7. -.-</A> Transferring phosphorus-containing groups. <a property="schema:url" HREF = "/EC/2.8.-.-">2. 8. -.-</A> Transferring sulfur-containing groups. <a property="schema:url" HREF = "/EC/2.9.-.-">2. 9. -.-</A> Transferring selenium-containing groups. <a property="schema:url" HREF = "/EC/2.10.-.-">2.10. -.-</A> Transferring molybdenum- or tungsten-containing groups. <a property="schema:url" HREF = "/EC/3.-.-.-">3. -. -.-</A> Hydrolases. <a property="schema:url" HREF = "/EC/3.1.-.-">3. 1. -.-</A> Acting on ester bonds. <a property="schema:url" HREF = "/EC/3.2.-.-">3. 2. -.-</A> Glycosylases. <a property="schema:url" HREF = "/EC/3.3.-.-">3. 3. -.-</A> Acting on ether bonds. <a property="schema:url" HREF = "/EC/3.4.-.-">3. 4. -.-</A> Acting on peptide bonds (peptidases). <a property="schema:url" HREF = "/EC/3.5.-.-">3. 5. -.-</A> Acting on carbon-nitrogen bonds, other than peptide bonds. <a property="schema:url" HREF = "/EC/3.6.-.-">3. 6. -.-</A> Acting on acid anhydrides. <a property="schema:url" HREF = "/EC/3.7.-.-">3. 7. -.-</A> Acting on carbon-carbon bonds. <a property="schema:url" HREF = "/EC/3.8.-.-">3. 8. -.-</A> Acting on halide bonds. <a property="schema:url" HREF = "/EC/3.9.-.-">3. 9. -.-</A> Acting on phosphorus-nitrogen bonds. <a property="schema:url" HREF = "/EC/3.10.-.-">3.10. -.-</A> Acting on sulfur-nitrogen bonds. <a property="schema:url" HREF = "/EC/3.11.-.-">3.11. -.-</A> Acting on carbon-phosphorus bonds. <a property="schema:url" HREF = "/EC/3.12.-.-">3.12. -.-</A> Acting on sulfur-sulfur bonds. <a property="schema:url" HREF = "/EC/3.13.-.-">3.13. -.-</A> Acting on carbon-sulfur bonds. <a property="schema:url" HREF = "/EC/4.-.-.-">4. -. -.-</A> Lyases. <a property="schema:url" HREF = "/EC/4.1.-.-">4. 1. -.-</A> Carbon-carbon lyases. <a property="schema:url" HREF = "/EC/4.2.-.-">4. 2. -.-</A> Carbon-oxygen lyases. <a property="schema:url" HREF = "/EC/4.3.-.-">4. 3. -.-</A> Carbon-nitrogen lyases. <a property="schema:url" HREF = "/EC/4.4.-.-">4. 4. -.-</A> Carbon-sulfur lyases. <a property="schema:url" HREF = "/EC/4.5.-.-">4. 5. -.-</A> Carbon-halide lyases. <a property="schema:url" HREF = "/EC/4.6.-.-">4. 6. -.-</A> Phosphorus-oxygen lyases. <a property="schema:url" HREF = "/EC/4.7.-.-">4. 7. -.-</A> Carbon-phosphorus lyases. <a property="schema:url" HREF = "/EC/4.8.-.-">4. 8. -.-</A> Nitrogen-oxygen lyases. <a property="schema:url" HREF = "/EC/4.98.-.-">4.98. -.-</A> ATP-independent chelatases. <a property="schema:url" HREF = "/EC/4.99.-.-">4.99. -.-</A> Other lyases. <a property="schema:url" HREF = "/EC/5.-.-.-">5. -. -.-</A> Isomerases. <a property="schema:url" HREF = "/EC/5.1.-.-">5. 1. -.-</A> Racemases and epimerases. <a property="schema:url" HREF = "/EC/5.2.-.-">5. 2. -.-</A> Cis-trans-isomerases. <a property="schema:url" HREF = "/EC/5.3.-.-">5. 3. -.-</A> Intramolecular oxidoreductases. <a property="schema:url" HREF = "/EC/5.4.-.-">5. 4. -.-</A> Intramolecular transferases. <a property="schema:url" HREF = "/EC/5.5.-.-">5. 5. -.-</A> Intramolecular lyases. <a property="schema:url" HREF = "/EC/5.6.-.-">5. 6. -.-</A> Isomerases altering macromolecular conformation. <a property="schema:url" HREF = "/EC/5.99.-.-">5.99. -.-</A> Other isomerases. <a property="schema:url" HREF = "/EC/6.-.-.-">6. -. -.-</A> Ligases. <a property="schema:url" HREF = "/EC/6.1.-.-">6. 1. -.-</A> Forming carbon-oxygen bonds. <a property="schema:url" HREF = "/EC/6.2.-.-">6. 2. -.-</A> Forming carbon-sulfur bonds. <a property="schema:url" HREF = "/EC/6.3.-.-">6. 3. -.-</A> Forming carbon-nitrogen bonds. <a property="schema:url" HREF = "/EC/6.4.-.-">6. 4. -.-</A> Forming carbon-carbon bonds. <a property="schema:url" HREF = "/EC/6.5.-.-">6. 5. -.-</A> Forming phosphoric ester bonds. <a property="schema:url" HREF = "/EC/6.6.-.-">6. 6. -.-</A> Forming nitrogen-metal bonds. <a property="schema:url" HREF = "/EC/6.7.-.-">6. 7. -.-</A> Forming nitrogen-nitrogen bonds. <a property="schema:url" HREF = "/EC/7.-.-.-">7. -. -.-</A> Translocases. <a property="schema:url" HREF = "/EC/7.1.-.-">7. 1. -.-</A> Catalysing the translocation of hydrons. <a property="schema:url" HREF = "/EC/7.2.-.-">7. 2. -.-</A> Catalysing the translocation of inorganic cations. <a property="schema:url" HREF = "/EC/7.3.-.-">7. 3. -.-</A> Catalysing the translocation of inorganic anions and their chelates. <a property="schema:url" HREF = "/EC/7.4.-.-">7. 4. -.-</A> Catalysing the translocation amino acids and peptides. <a property="schema:url" HREF = "/EC/7.5.-.-">7. 5. -.-</A> Catalysing the translocation carbohydrates and their derivatives. <a property="schema:url" HREF = "/EC/7.6.-.-">7. 6. -.-</A> Catalysing the translocation of other compounds. </PRE> </div> </main>  <footer class="footer-grid"> <div class="footer-elmt"> <img alt="SIB logo" src="/images/sib_images/sib-mark.svg"> </div> <div class="footer-elmt" property="schema:creator" typeof="schema:NGO"> <a href="https://www.expasy.org" target="_blank">Expasy</a> is operated by the <a property="schema:url" href="https://sib.swiss" target="_blank">SIB Swiss Institute of 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