CINXE.COM

<!DOCTYPE html><html lang="en-US"><head><title>Just a moment...</title><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta http-equiv="X-UA-Compatible" content="IE=Edge"><meta name="robots" content="noindex,nofollow"><meta name="viewport" content="width=device-width,initial-scale=1"><style>*{box-sizing:border-box;margin:0;padding:0}html{line-height:1.15;-webkit-text-size-adjust:100%;color:#313131;font-family:system-ui,-apple-system,BlinkMacSystemFont,Segoe UI,Roboto,Helvetica Neue,Arial,Noto Sans,sans-serif,Apple Color Emoji,Segoe UI Emoji,Segoe UI Symbol,Noto Color Emoji}body{display:flex;flex-direction:column;height:100vh;min-height:100vh}.main-content{margin:8rem auto;max-width:60rem;padding-left:1.5rem}@media (width <= 720px){.main-content{margin-top:4rem}}.h2{font-size:1.5rem;font-weight:500;line-height:2.25rem}@media (width <= 720px){.h2{font-size:1.25rem;line-height:1.5rem}}#challenge-error-text{background-image:url(data:image/svg+xml;base64,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);background-repeat:no-repeat;background-size:contain;padding-left:34px}@media (prefers-color-scheme:dark){body{background-color:#222;color:#d9d9d9}}</style><meta http-equiv="refresh" content="390"></head><body class="no-js"><div class="main-wrapper" role="main"><div class="main-content"><noscript><div class="h2"><span id="challenge-error-text">Enable JavaScript and cookies to continue</span></div></noscript></div></div><script>(function(){window._cf_chl_opt={cvId: '3',cZone: "pubs.acs.org",cType: 'managed',cRay: '922e9425dccfdaa5',cH: 'FTZ_Jvapus9IVF0mtPyfiQ4bMc2tEuZEWbzpwTTYzcc-1742404178-1.2.1.1-hb.8KHxKlwGRTQlwDfB6qXqVfilkUxdxVy76jpXZ41hOlLFTOZVXjnhQyQJpjvPw',cUPMDTk: "\/doi\/abs\/10.1021\/ja01608a014?__cf_chl_tk=tyovGTswBZEdqfpfMHINNRfjj5MUWo6G3.G.YGayiOU-1742404178-1.0.1.1-QJHiSKEhzoEyh144AtsCcio37HvAkZP1Za7RgkdSdSs",cFPWv: 'g',cITimeS: '1742404178',cTTimeMs: '1000',cMTimeMs: '390000',cTplC: 0,cTplV: 5,cTplB: 'cf',cK: "",fa: "\/doi\/abs\/10.1021\/ja01608a014?__cf_chl_f_tk=tyovGTswBZEdqfpfMHINNRfjj5MUWo6G3.G.YGayiOU-1742404178-1.0.1.1-QJHiSKEhzoEyh144AtsCcio37HvAkZP1Za7RgkdSdSs",md: "uePRQJyXlspkKT9k2zEjQw0o9UDL8gXfoCOIt.Sf944-1742404178-1.2.1.1-.HRVk9W2zUYDKO_aLVHkFKfQOkUrfzOVS93WcehoECT7dA2DzL4GqR5k8byY.hkxf2jx.bfJeZ0yS4REW5hiyAclmia6FzhFQl_vhMEFZUosYfMy5Zv8mAJ.6KWqRlwuoYfh8UbC0VMcwxXU3X7fWp2mvk6vDCTOEsZMHV1HZXl_7jO1S4TdsJdSsKjSEyx_TyR.jp6xBC6yLn6ecCjTa7g_eusRl_rrNIVMOytv0kebhhjVTRbuuQjz5gavfqoTLR9KAFDBZdsWk1Ar6j3KNzeCU0J3xvOoniYgVdvL2eFsIFQQFFB4CMf1paidWlDbQwyTVvHyxSQJTCTZE0JvO57ytIsVZHFaDQ2oAk.DKRXNvdX7HS99p30tW.lneI9BnW9HgbRax8.p8LqxStgMbRpgpLJzqp5lDJN5RNGMbIl8mNb1K4d.5bS7QEAI9vDjc0dJxJHXq2qZtI46hJdbX.ucudSxTm5z5r9J.X0oQQBGW6tXagLEFIny5NL2rWmWnojC2oCTMxePTEjhhgtWybQUk3KzIMIlMm9QtExPAEwVTgQ8vaOFJADsy8G7xfCWIAk4I7wbeoYEwBLMNmpr4PLc14IwyUmpjo1HsuonFWPYVZ5PrPO8x.m3J_7jQxG6_2W0zNanEl._rCCbDGQSQxAQB2QTKM6xjvIXMmY1rvonK0J9M490kozR5FKUl3u21AGa2.Grm5oEw3wfkzbmMeVEFdyMCSCYZZQKQeEjRBeW7egWAvV9VZpXxPUEMnxU.VOrHTIR7YZ.BBTXZ2gzb036zyZN3jPT5jOivbLQYi_qXaxOrkKv2Vs8G5ax.LZb2pW36vabf38974ZR5eZM8kYQCZp1cTa.L.U553dmH4bO21gls5Fva1uFLklF1_f6u8DaGOC9OIDIUwYTs_9TznZmZTpkixEsdkHRTnmIcQ7TXvzU8CPhY45fA0NKGivHSUX.5cfsomUBHtR.O5JWrGL_1YUrzGmZsvAuwXfb8qg_SZ4aqWNS47BYnCFLKMci8AJDUtHW8cca2j.DXmhDQiwKD35aeW4zKCK.xq3rjFYgtHf7kWSVPpzwApX6f5mx_8QcTPlUjavW2GhyMMVm9pN7Op_fG3m1rmjHdpSx_rBrqzAq23P5X57KXFSrKl3HkoPbbzY3r77XQUCcURUNG5Xol3cv7AtzqEecMT7SxrRRSScL6dMj1b8Zv2AG5VmnFyldaeLOvfNgJIAM_ULZT_UwVcYyWPKEvh9vhxge1KcU8DI5MafbSSuCE.5YNTB7SWCSpHGwcudYd8KXpIpm7A",mdrd: "SQmT0tdwKuUtLiOXHmv.scg.Luc7.lCtNsyA4n83ZVQ-1742404178-1.2.1.1-AGGWV3qSkH9UhCXFDIBcrXmoUNW12MTcBfw.DaiumyR0d2McR1pd.IUvUg90opiQje52AUJK9bCpwz.YfJQEIgQK1VE.AwieRszJSudrb3JroWjo_zO7imIksZK9t82LlD4DGPh6P_hvFZ4JAGk2Zo5pnYyfAaSrIm37celnz6M7gTJ70xX.jHUVJL0h7rvxjY8ZNjDcnzCXr11jSAkshRw5.aoZjBR1rgqa46ROVVIUEgFiUb46SKny0x8kVRnW1DgA0xLb_hyTNqT0Tj2HVQcCJcWejj70X.eyOWGyiJDAA8aYs99GZIeJ.D6Ex4udVit9zsHmsXGSD4CiETc9_sLreVF6OocIJtrjC1XctOCuEdZtySRl0S5VoU81aEhZqCQ6R9fiyjjA.YC0q4FlATSWS5cYNlDDMlJLK2Y4NjCqtNq23PtrZzG0OckiObbukp5Vepwtx4qe_eGu5Y8VxhE8XQ.LrThUy0ITUSXre4wWcwAoxVDbiGdV_IHHjnu.Ix_VPxA6SvrV92XQKUFost0p_zr3LpRudqVUligsedBPFmPWNapGDFQMKPUXtWZz6jKZeoCSxhX2Fjf3bBc2OCe27cS57KttoUj2jtkD1Fkv7fkyC.60mh1otlLOc17rKtmOTHI7oWhUvRmDKA5RNPspZ.K9dSUMaQgWOSla.yFxpBFOYg4B8lprUBCdfsqarzRB6eQasfrZpLgclJ8sz_8LlCEDRqYzCtv7Sc320xx6mFIo2aKAASoxcq7krGE0wV5jFaYDFEGbnuNY_KbkVk.jdpNTh4_kZOfEyMMwUqWmWnB2lA0V.jb6xTN9OoDS2KL_SBkkPHjBBFI3J95_ur0cUYhCNqZ5A5BlnewPntRVzN12H.KbNRcU.1KlLN_DlvB8f_i_Y3w66MhHUMa.YhPcyTUSikOPle1afZ.n6dpBt0yaT5WumNz99wVuYhSI_9QeVnXEQTdbK1LoQck9EZGiyxzdZLkoqKwX0MrhJKeKekDqqlzvIQWaNVL2Ad8Hri_JsEr2kIRRc2HQVlhMVLH4TSzpIiT5_mmIjz18p_43SZG.fkLE8NUwQXAta81vDKqRdNWomFlFhI6KIpcULRk0oJf4iYwdHeXIRS6djUOmDBPGdjQE3usWRaZum4LWt29_5k1AZcGIdlIzNOTnKrV7TMf1CXIHENYF2NG_SblH.p3Q2OZShxTAwvfwPVoT96VrGJcXOTDcoyY8fxfwUsyhJOFxPdBaCJOe4_Vfb83aiU3HRAHM9aEFiJmS.5c1Dui90Jaq5RdFOVFHTz6jW_ElJRHp3GMMeCw1GvSeKmJ4WbB5Lr0doP2BfrTLuh4z3RtDOWe.9V0RX1UNcfWHfcMDrU6h7B0aU9IzCEtrx.3es9uK4ZMJBzyuYtyqQyxQds6FE86bAJa8KMUqyr_fYmS4P1uHVihRAKBJkBj11ZpEG7F4fA6etTux42NnIoc15WUgVPGTWZqS94o8.m9duLXlLWfuk0tY1v8R0WnhVxtNWh1u4gkpxjqJvlqNa5My1xwngtCJEunvZvxRy1CrH9gc0LkTTGAf.P7.9H3lLKf3oPpC5v.v9RBxaz65rDe3EQ.JaOFen55wak59OcAwWEXVrlma1JSXVgXbVmUBgmFBw9r9u5IqlxC_fqug6ZXGMe9XnRXbfQRwq2UoIKZpzzk9kPVgNVE.OXXnSYbZWF3GV5HPuE6eP64nTePhay7GQ52pm1SnWjgx0enzxhrBa4b72PpGVpfjYZSCdg9hNxHfh7vh3DJyZPSjOKJnSkgy33aVR1_XHbTMh0LzGcmUVi1lKWOlhGUXHmw3L5bBZ_ioXJTeLq4Fy6HBDbPOi3x0Taq0mpm.IOtFAqIKc5gTQsliKehMWlmSGHvOklfCQnL2rEZekYsvzsM7ocnrfbbK2K.nAri.5FQu3n1wnni_fsCkzoN_d0bBsPnWqghLX6WlibyaaCKAMTb0azom3pJxTZOpnf0_Zu2k0Jk7jFsX_hO4gp1igpg4cuM0tM0nmAg3ALdk4vBZtQ_Nm.v7QbcBl1eHyw9CDwHj36KaN6CsAA"};var cpo = document.createElement('script');cpo.src = '/cdn-cgi/challenge-platform/h/g/orchestrate/chl_page/v1?ray=922e9425dccfdaa5';window._cf_chl_opt.cOgUHash = location.hash === '' && location.href.indexOf('#') !== -1 ? '#' : location.hash;window._cf_chl_opt.cOgUQuery = location.search === '' && location.href.slice(0, location.href.length - window._cf_chl_opt.cOgUHash.length).indexOf('?') !== -1 ? '?' : location.search;if (window.history && window.history.replaceState) {var ogU = location.pathname + window._cf_chl_opt.cOgUQuery + window._cf_chl_opt.cOgUHash;history.replaceState(null, null, "\/doi\/abs\/10.1021\/ja01608a014?__cf_chl_rt_tk=tyovGTswBZEdqfpfMHINNRfjj5MUWo6G3.G.YGayiOU-1742404178-1.0.1.1-QJHiSKEhzoEyh144AtsCcio37HvAkZP1Za7RgkdSdSs" + window._cf_chl_opt.cOgUHash);cpo.onload = function() {history.replaceState(null, null, ogU);}}document.getElementsByTagName('head')[0].appendChild(cpo);}());</script></body></html>