CINXE.COM

<!DOCTYPE html><html lang="en-US"><head><title>Just a moment...</title><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta http-equiv="X-UA-Compatible" content="IE=Edge"><meta name="robots" content="noindex,nofollow"><meta name="viewport" content="width=device-width,initial-scale=1"><style>*{box-sizing:border-box;margin:0;padding:0}html{line-height:1.15;-webkit-text-size-adjust:100%;color:#313131;font-family:system-ui,-apple-system,BlinkMacSystemFont,Segoe UI,Roboto,Helvetica Neue,Arial,Noto Sans,sans-serif,Apple Color Emoji,Segoe UI Emoji,Segoe UI Symbol,Noto Color Emoji}body{display:flex;flex-direction:column;height:100vh;min-height:100vh}.main-content{margin:8rem auto;max-width:60rem;padding-left:1.5rem}@media (width <= 720px){.main-content{margin-top:4rem}}.h2{font-size:1.5rem;font-weight:500;line-height:2.25rem}@media (width <= 720px){.h2{font-size:1.25rem;line-height:1.5rem}}#challenge-error-text{background-image:url(data:image/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHdpZHRoPSIzMiIgaGVpZ2h0PSIzMiIgZmlsbD0ibm9uZSI+PHBhdGggZmlsbD0iI0IyMEYwMyIgZD0iTTE2IDNhMTMgMTMgMCAxIDAgMTMgMTNBMTMuMDE1IDEzLjAxNSAwIDAgMCAxNiAzbTAgMjRhMTEgMTEgMCAxIDEgMTEtMTEgMTEuMDEgMTEuMDEgMCAwIDEtMTEgMTEiLz48cGF0aCBmaWxsPSIjQjIwRjAzIiBkPSJNMTcuMDM4IDE4LjYxNUgxNC44N0wxNC41NjMgOS41aDIuNzgzem0tMS4wODQgMS40MjdxLjY2IDAgMS4wNTcuMzg4LjQwNy4zODkuNDA3Ljk5NCAwIC41OTYtLjQwNy45ODQtLjM5Ny4zOS0xLjA1Ny4zODktLjY1IDAtMS4wNTYtLjM4OS0uMzk4LS4zODktLjM5OC0uOTg0IDAtLjU5Ny4zOTgtLjk4NS40MDYtLjM5NyAxLjA1Ni0uMzk3Ii8+PC9zdmc+);background-repeat:no-repeat;background-size:contain;padding-left:34px}@media (prefers-color-scheme:dark){body{background-color:#222;color:#d9d9d9}}</style><meta http-equiv="refresh" content="390"></head><body class="no-js"><div class="main-wrapper" role="main"><div class="main-content"><noscript><div class="h2"><span id="challenge-error-text">Enable JavaScript and cookies to continue</span></div></noscript></div></div><script>(function(){window._cf_chl_opt={cvId: '3',cZone: "onlinelibrary.wiley.com",cType: 'managed',cRay: '8e6e09845ff581e4',cH: 'rhxv7pNUswZu4RVryErTJxhnp2nwfRqUxYPqVNmh2Hw-1732332170-1.2.1.1-zYNkEPbcxG5Lgoc6avKSyiRyeKFtMo8urYBdLpO9.heY5Z5co3k0pJlVDDjRZTH8',cUPMDTk: "\/doi\/abs\/10.1002\/jcc.20495?__cf_chl_tk=Ex0fiCz4wJHbrKw8.bnyxaZs6SZXD7kdMbyPrZEmQk4-1732332170-1.0.1.1-t7KQoB1zbbDit9zait1lEgsBoLHgdfq5Z0aRL.SPtFw",cFPWv: 'g',cITimeS: '1732332170',cTTimeMs: '1000',cMTimeMs: '390000',cTplC: 0,cTplV: 5,cTplB: 'cf',cK: "",fa: "\/doi\/abs\/10.1002\/jcc.20495?__cf_chl_f_tk=Ex0fiCz4wJHbrKw8.bnyxaZs6SZXD7kdMbyPrZEmQk4-1732332170-1.0.1.1-t7KQoB1zbbDit9zait1lEgsBoLHgdfq5Z0aRL.SPtFw",md: "yd5F8XqQ2sbZ1QNwoG7sfDQpsgqvTWzoKb6u1k6h_as-1732332170-1.2.1.1-KE7XYQnx9ovk4ReWK1wzXlTooNITszxpNcQKsDSy6FZqSlGzf6bPoXT.QCvuLpuaJCJKLhjWdku2UeGmx3i2NcoAMqAf4JVu_1lfwCEpD6H2pmpQtOjNFbU8J.VrqUp9evU2CGg0EEX_zM1BLOrtb4A6bDSftOfreR3YGr.sSWNOPQEUkCxSfayQbPUnI8uAS1kP.Ix_gTakLtKXO3.x0G5V5sMv.wmTcw1L_GoFF6nQZdxad6ad4nMf4kU5Re7oIwr7RStALVvoUN3LqNgRlvhTnKvQcWLgwOqieU48FpS8vTfLiJDxqYwAWL193utFewZsEaIUfcUNKF09FZ7ySdAmXTZlWh6.M.SCUyTw7o3wqYUsvJDVzgsqh2Kr83fBavdxwGl7kGDuGUQKtRit6QvV3gEV1wZQqE7SoEqRmgoVY1P_fBXfzsDGyKPIP2Xme7JE5vB6D8Fd8J4ueRimWZ5guyKNGNDZ2udx4D9Lt2IBvylvUhzcCS36TMTvbiJR7w2LOEVRgnAz6.s83Lat6FWy09T_WE7r4iRqRBWQhAjlXlFE8yEyC.ctSbBL116ijeyhR2F6VYJbW2lkG7Sf4xF74rIwveYOGKr3DOdjbGfELx2e00_QuBsu2jKu2vkp_8xbsv5qyGT4soTvbU9JWcGGKvh.2Y7qgliRoVJ6h04RjtfWxuC7ju4a8cGsfwmOMhJrK0YZ7QN4gqKIv.KN_rB2iv3fj1nboF8vdroEqNqNAXAdBgzn30.b4dgmrbSgvi3eLxv2Sf6MGD_c9znvkW1TeF8ECGQrlHhIv4B9S_FS9qw2Jv9awQIWFXSOLt3cu.wqTWVw24j.UEm39_ulSpN_7bTEjMnx1AJLhGT.PktnAwhDQakeSCkl2S7ZeMfDPkcF7i25KKs7t3RPcrApqiXi1.kUcWBXfyaZ78Fp9NO9d7hcg.dY5d.D4nQ.4LVY63.v0oHgl.OHg1UkrlVBKH9ckRE22Eoys7Vd7mmeVKqh2D0KHxSDNocF6hFK84XJQ987OX0LyCbO4U7JbnQ90j8iWHs4jz4hjHKTDnbjLe8CnufE19jZafjrp.wMfp4URoCS5THNUZeEOO6RE14kVluEWtwVYpyANlu71w0YISar2tLRxT6.EBEzz1tVfn58SekpWfeBA3o3lspGhVMt6sjXYl7sT13_UESCAFthOMwfEKUmLP2NdaIfOsUGBf4lG8uVqtaLzb3FvneUuO0D6Ct0WF4FuQTv2BV1maj1oUdt6U_nZO.WVUq44qREKbrD9lqnvd8WgwOUztmjvhFAuUehelbBkS7ixcjA.PChCdJ1wN8Shc7vg2jcQzHdkD9PNAoYHa5GPjOrgVk0j6BdCxSBVtxRPPuVCGnPk8oXdT9eB.S5BXa1UIOTKcbIJjYheI5dei9YtjlqYQUUEw00swmBNZ2Km8tymaC7BhzYHHCOMXvDoWr2aNeCKA5ls1fuYbH0n7nmmkAhQIWAffHsZvsTAvImITOVKwAgZpd5zPWPSn1pSB7l0A_GBcWMQgtIu61iVUvNZfi_J6JyBCBXxkFU.x8l59.esx_D8p5BS7FPa5GLhwiOjnobL1wj4XOGwld4v_RSqpjc569NV5sTYZ8mxDeYictbYWo4xDyKYkL_D1QfrWHPJ.zpSuesiVymGyQ353q8P3ru_7Cb4m5YkvSIVvG5T8SNw.UXjbXNZ_NwUr04W2ssl0wZMl_05GVfSTIahmOSTUezCxokJOgdzV3SYbicCWafkbJeVKMGCY_l2koi_1T06.rwkcszGHYj0rgchU4Ati4MeTR.XNMvcvweUOpS4c.2v6PMgDPdyzvDFG2YzMl6HmrhmpiDd6XKfFeL4EnGKN4.7qsDkFJW9dDSWxdqReSYetT4xFR34lceOufYk1mxoXhROnZRu7gToT2GgC.318qgFyUl1IjJDbN3njOuH6zhykQMSDS6Z5rAnAGIa0Uz308qV39nzDyOTpdPCWCzY492a7.hMHnf5XAwGngGbSwWCOkRSXPULrA91o_fmEVN3ucYfsiyeEzBwmc98npezw5PGc34RYxWcD6BoUZx1uuB.4UrtjarMWMnzaR0WIE4NaAz0ThWpXuJ.Tu21FwmrRomkUMzWXyxltBV.qS4ekQCgwIptzJzPp4QoDSRWJ6gLUEU2kzLCTWbs8wplki97bw73d.XYDgkN0lta3tBxkfHpfZAVRTKcGCnCMStfKdHr5lqArrF_H7LhRUxOpNHonZLnFg.NVHAK3T0FB.wQ03tZ8vM8nDn_VpUcfCYccgJPQ.M_eC54BV2o_kX4G..1sJCBc08ilXXOJ1M0kjF8rYYhH7SS4XkAHDCwupFJRuPYam5eALHrOXttgkdCfVYxIId6nyBz.thTuQsVEn_mBub8wtKiC91EsUfb03t61Vr4DXipLZ_5l.T2OOMHV_L9mQv5uWdTDbYfMTqX0Z724GAbW..erIjZqy3jlA05s1zOyFazF16LR1_Miy1AFRIrPO0gEHg_Y9FRtm.ll0x2ja3NhpwgjeCUO5ZypvYIf3ydEOYgiWvc_RBzlDiRv8Uahb9XrFwyyYn7QhfG8wQX93vHbSW2FzWAnNfraGGCFRe1vooIibpA.qe0hqDj2Rx9m_z.86C2zc5d4u9DxXBgokP0FPgnGZgEutZQglbA_3E6oLK8EyoX2TYpzzyFgew3zXfxJn6LuAgAPGpzfMwYauyBKVHWjYDNqCLr0X1TLh2Xki_5lBWEcNeU7p9hbXqnomz7iMcLeVddth3zoFhsgVqB9Z6LQdreO1xl_ME7ZtOCjFFA425fMshan3_jwqkLI4K75ShEC427HrX2RtQykLhHYHCp98hOjXtu0x_WIs3c3JHEKdT_rgZMO8OBzj3y6nbebyVIq.BM0A4aheJxIEp.8WhqkGbn3oGRtJjLaaQetRjIZ1S2YkneNP2rX1Ba..oKfy7jmGD1Y9pe4gLJDKE8DBK1kDMLs4",mdrd: "ZGubjchaOsvojL.uryiIca7iHWhBqjC8AGFV3gNLYQs-1732332170-1.2.1.1-IeFMeIMp35LwLP.HiHo18ECP6NWc4FT8DnhAXwopWEHmbqi4nFBgzU4aK1hH10tImkjauShcOkExcK.UZuvVzRqXuQvirxHIfj48JtqtvYRbSCxtV7OGUPrKxYYF2v1LA1w7A1FhiRGmJqrpDw9szYZC_wjLBkLIL7PeaIr5B9BHnYExWgC6yFCPutYgjjzQE5sxk1wdUssuWEQXlEu8IPnbqiYn6cgDlWtCoF1VAW63Vgz34C7rlcd684O2upTKY2amYBClt1ls4qWUSqziPLPDJWUcKi4jcc1gDy80ThnHIvkTuEEGG6d97X7rNU7EJqipTanTH93CPzcvYps5R8pbfNYMjDVIrhxEwI4TFDtJoKzSyUYaKyxHdItXHSiO.VVIR2P._u8Ci3KdJ9HNkfWRv4bWYFH4IDfEsTEwoSKPcPVNGkN3pvHxcAQJa51nXRwgJSfO2hNsMzUaluEp4DNHzNe4azQtDZqIKln72wRlHhUAlWbCTYs9NNL929O7ciiow1QmRngHK21NUFdrzMvxghmSHbDDAZjtMixL6g5uxXs2QDHLOsGaLWucbKxrFiPb3FnVKPwmGD.pA6IvaDaEZSm.dYgfTDBl2f6DTOzTHE1_SA3cLpmGHgLGe730bOlSAgPz_9pd2duYGeOnr4UsMZhQau9L1murzmC5vvxrIvsS.0RQgTqipQ7qDwDWPbuBFQFwEIKCl72ciPwIp9Zyr8mHF0ZNZemZLc8O0KW8rzP8upaeQhJ7BKAlx7YlVPw2zyhf1wUwszHen.1qyIpnRT22x7Y1SOB_pL0lglfn1ERBnDjkncq36sN2MHCQ5ZS9bUIAic7nm.RVRO6uQc3Ogkx1aDClnR8RvAVL1ChkyfRmR9Bt7e5h1GIlZ8agsjijq1EuJXBukNDz54abdADxrGegOOH9xdB4Vp8nwfjp1ddvDKbxVpmYORonVO1xNi.xnV9VHp7tftS.rHDmhlExTxOkL85_RkpcnP4OeQBsTz9pDW_0tnvTfsSSAmQ4FSeCyJenQzWIt9G5jqLTw7rcEL8MkKMvGj0Nqy_.dvv5i7qLvAAvSUC1BDjbjzncL.iIrqDgtoVuMzjbXqhB1kGXDMKGVPponBFTCIXtxwy.M9wuL9eqcwjVZC_IVtyefRACuVYCfGycEJjyhTO88ZNsdPYgDmArtIYk896cAecvHpwhzuIy7KiqlPtlXNQFHoIGiLfPV2DPBdBuFYvyWRxuY2uY13.Czrq_A_aDealfBcGOq6500odiDN38oj58Ebu.JaI8VTfjyUHD0Mbrp.7hrgkBtZ3qV1Ok1yBkaOi02krlJ6oPk7iU35Elv7Xgus_jWwRY9KtNVIR3GPPJLz4mtNgVhbmhzJIjJIohT1wclsThP0hQENEu3xbAkDnrTFpzU_w87CLkrZ1n_aojVFrKY9ynys.CXftC7dhi9IS5se1FQsDXUXgJEfZMT31WHbxmOG0lwhFiPI.h7tu332DS8LIxEvvFs1NJBbZuwwcXfTK..ljUFmkhVCt4uuuipdPNerXXem00S_tpmBG4dLZ9nQ3UER_Cmuu.CSzCFLJ6lT4oU.EiXuKu0aGlXsrzGIcykgTU9SfG1cu9OZ3BaMDK6blBjdPWrMf7nqRkfL6ZkgzCAotBkaOZxgT5suoaGLG6xo5h2gJm.i6WxPm7ZFFpkwPlQXfrk.BEFNUP5eLid4li5NlCtn6wJgltT1t_BczN.v2iqYpRx4Hp2wtV5CvuxaTzooUHZPPhzX3bAPhMBqg4qeakaKn07a.NNioN...MYjn4Dh6xPZeVHYsYb0ZlEOHgr8y8IyItVjTU3ZE0F2n6r4Mm6JmcataX3Ms.wzNqUNqQh3rkVSpNSRrwTUNBuo3w5Rh_oU1Ub0JJgDfi2jhlrfS6BqyDMxfXDq.gQFz746PXRM_ncpyZ4v7nVkOArxFg86Suk7yF8ZN9APpRb9EgjdZiV.H1ypodaSTYQGuhrF4Jg4aXmVEUg__3aw"};var cpo = document.createElement('script');cpo.src = '/cdn-cgi/challenge-platform/h/g/orchestrate/chl_page/v1?ray=8e6e09845ff581e4';window._cf_chl_opt.cOgUHash = location.hash === '' && location.href.indexOf('#') !== -1 ? '#' : location.hash;window._cf_chl_opt.cOgUQuery = location.search === '' && location.href.slice(0, location.href.length - window._cf_chl_opt.cOgUHash.length).indexOf('?') !== -1 ? '?' : location.search;if (window.history && window.history.replaceState) {var ogU = location.pathname + window._cf_chl_opt.cOgUQuery + window._cf_chl_opt.cOgUHash;history.replaceState(null, null, "\/doi\/abs\/10.1002\/jcc.20495?__cf_chl_rt_tk=Ex0fiCz4wJHbrKw8.bnyxaZs6SZXD7kdMbyPrZEmQk4-1732332170-1.0.1.1-t7KQoB1zbbDit9zait1lEgsBoLHgdfq5Z0aRL.SPtFw" + window._cf_chl_opt.cOgUHash);cpo.onload = function() {history.replaceState(null, null, ogU);}}document.getElementsByTagName('head')[0].appendChild(cpo);}());</script></body></html>