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David I. Satzer (United States of America) - The 20th Biennial Meeting of the World Society for Stereotactic and Functional Neurosurgery
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</div> </div> <div class="container navbar-level-2 scroll-bar"> <div class="navbar-module-actions"> <ul class="nav navbar-nav navbar-right"> </ul> </div> <div class="menu-overflow-mobile"><i class="fa fa-chevron-right" aria-hidden="true"></i></div> </div> </nav> </div> <div id="content"> <div class="wrapper"> <div class="person app-person container"> <div class="page-top"> <!-- <a href="javascript:history.back();" class="hidden-print">Go Back</a>--> </div> <div class="list-view list-view-list"> <div class="card item-container"> <div class="page-container"> <div class="person-details "> <div> <img src="https://cslide.ctimeetingtech.com/global_storage/media/content/wssfn24/persons/photos/174.jpg" class="photo" style="width:240px !important;"> </div> <div> <div class="details"> <div class="property-container"> <div class="card-title person-title"><a href="https://cslide.ctimeetingtech.com/wssfn24/attendee/person/174" class="item-expand-action extended">David I. Satzer<small> (United States of America)</small></a></div> </div> <div class="property-container"> <div><i class="fa fa-building" aria-hidden="true" title="Company"></i> University of Colorado</div> </div> <div class="property-container"> <div><i class="fa fa-briefcase" aria-hidden="true" title="Department"></i> Neurosurgery</div> </div> <div class="property-container"> </div> <div class="property-container"> <div class="cv">David Satzer is a functional neurosurgeon and assistant professor at the University of Chicago. He completed residency at the University of Chicago and fellowship at the University of Colorado. His clinical interests include the surgical management of epilepsy, movement disorders, and neuropsychiatric conditions. His research is focused on local field potentials (LFP) in epilepsy. Specific areas of interest include single-cell contributions to LFP, computational models of LFP, and use of LFP in neuromodulation.</div> </div> </div> </div> </div> <div> <div class="group-container"> <h4>Presenter of 1 Presentation</h4> <div class="app-link"><a href="https://cslide.ctimeetingtech.com/wssfn24/attendee/confcal"><i class="fa fa-calendar"></i> Calendar</a></div> <div class="confcal list-view"> <div class="card presentation" data-id="58"> <div class="card-header"> <div class="actions hidden-xs"> </div> </div> <div class="card-block"> <h4 class="card-title">DIRECT TARGETING OF THE CENTROMEDIAN NUCLEUS</h4> <div class="details property-auto-width"> <div class="property-container internal s"> <div class="info">Session Name</div> <div class="property"><a href="https://cslide.ctimeetingtech.com/wssfn24/attendee/confcal/show/session/38">0450 - Flash Presentation Session 01: Epilepsy I <small>(ID 38)</small></a></div> </div> <div class="property-container internal s"> <div class="info">Session Type</div> <div class="property">Flash Presentations</div> </div> <div class="property-container internal s"> <div class="info">Date</div> <div class="property">09/04/2024</div> </div> <div class="property-container internal s"> <div class="info">Session Time</div> <div class="property">04:50 PM - 05:50 PM</div> </div> <div class="property-container internal s"> <div class="info">Room</div> <div class="property">Vevey</div> </div> <div class="property-container internal p"> <div class="info">Lecture Time</div> <div class="property">05:11 PM - 05:18 PM</div> </div> <div class="property-container internal p"> <div class="info">Presenter</div> <div class="property"><ul class="persons"> <li><a href="https://cslide.ctimeetingtech.com/wssfn24/attendee/person/174" data-id="174" class="" >David I. Satzer<small> (United States of America)</small></a></li> </ul> </div> </div> </div> <div class="item-content"><div class="additional-materials"> <ul class="nav nav-pills logged" data-module='confcal' data-log_entity_id="58" data-log_entity_type_id="25"> <li><a data-toggle="pill" href="#presentation-abstract-581207040845" data-log="ATTENDEE_CONFCAL_PRESENTATION_EXPAND_ABSTRACT">Abstract</a></li> </ul> <div class="tab-content"> <div id="presentation-abstract-581207040845" class="tab-pane"> <h4 class="pane-header">Abstract</h4> <div class="abstract"><div class='abstract-section' section-id='0b79795d3efc95b9976c7c5b933afce2'><h4 class='section-title'>Introduction</h4><p>Stimulation of the thalamic centromedian nucleus (CM) is an emerging therapy for focal and generalized epilepsy. Historically, CM has been targeted indirectly due to difficulty visualizing CM on conventional MRI sequences. Fast gray matter acquisition T1 inversion recovery (FGATIR) is a clinical MRI sequence used to visualize subcortical structures based on relative gray matter content. Recent optimization of the FGATIR sequence utilizing deep learning reconstruction has resulted in substantial improvement in signal-to-noise ratio.</p></div><div class='abstract-section' section-id='20c51b5f4e9aeb5334c90ff072e6f928'><h4 class='section-title'>Methods</h4><p>Optimized FGATIR sequences were acquired in 10 patients with epilepsy in advance of thalamic deep brain stimulator (DBS) or responsive neurostimulator (RNS) implantation. CM was identified as the relatively hypointense region lateral to the mediodorsal and parafascicular nuclei and anterior to the pulvinar. Individual FGATIR acquisitions and manual CM segmentations were normalized to MNI space for group analysis and compared to the Morel atlas of the thalamus.</p></div><div class='abstract-section' section-id='fd69c5cf902969e6fb71d043085ddee6'><h4 class='section-title'>Results</h4><p>CM visualization was significantly improved on optimized FGATIR relative to traditional FGATIR. The medial and posterior borders of CM demonstrated greatest contrast with neighboring thalamic nuclei and were identified with the highest accuracy and precision. Lower contrast was noted at the anterior and lateral borders with sensorimotor thalamus and the superior border with the internal medullary lamina. Six patients underwent FGATIR-guided placement of bilateral CM DBS or RNS leads. Postoperative atlas comparison revealed that all electrodes traversed CM, with a median of 2.5 contacts (range 1-3) in CM for DBS and 1.5 (range 1-2) for RNS.</p> <p><img src="https://s3.eu-central-1.amazonaws.com/eu-cpaper-prod/mediafiles/wssfn_24/0000000058/000022.jpg" alt="fgatir figure.jpg" title="fgatir figure.jpg" thumbnail="large"/></p></div><div class='abstract-section' section-id='b651e8a99c4375feb982b7c2cad376e9'><h4 class='section-title'>Conclusions</h4><p>FGATIR is a useful and readily available sequence for accurate targeting of CM. Further improvements in CM neuromodulation may come from combining FGATIR, specialized MRI sequences, and emerging data regarding the optimal stimulation target within CM.</p></div></div> <a class="nav-pills-collapse" href="#">Hide</a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="footer"> <div class="footer text-center"> <div class="footer_wrapper"> <i class="fa fa-chevron-up" aria-hidden="true" style="display: none;"></i> <p>Programme and Faculty are preliminary and subject to change.<br /> <b><a href="http://www.surveymonkey.com/r/MSHLPYT?c=7647_The 20th Biennial Meeting of the World Society for Stereotactic and Functional Neurosurgery_2024" target="_blank"><span>Give Feedback</span></a></b><br /> <span>© 2024 cSLIDE </span><a href="http://www.ctimeetingtech.com" target="_blank"><span>CTI MEETING TECHNOLOGY</span></a><span>. 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