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class="post-single animated fadeInUpShort clear"> <div class="content-block"> <div class="title"><a href="https://genetics.med.upenn.edu/new-department-of-genetics-website-in-progress/">Genetics Website in Progress</a></div> <p>An Updated Department of Genetics WEBSITE IN PROGRESS. Stay Tuned!</p> <div class="button-wrap"> <a href="https://genetics.med.upenn.edu/new-department-of-genetics-website-in-progress/" class="btn blue small">Read More</a> </div> </div> </div> </div> <div class="button-wrap clear"> <a href="https://genetics.med.upenn.edu/category/announcements/" class="btn small red">View All</a> </div> </div> <aside class="publications"> <div class="title animated fadeInRightShort"> <h3>Publications</h3> </div> <div class="list clear"> <div class="post-single animated fadeInUpShort clear"> <div class="content-block"> <p class="c-article-title" data-test="article-title"><a href="https://www.nature.com/articles/s42255-022-00531-x" target="_blank" rel="noopener"><strong>Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes. </strong></a>Maria Fasolino,聽Gregory W. Schwartz,聽Abhijeet R. Patil,聽Aanchal Mongia,聽Maria L. Golson,聽Yue J. Wang,聽Ashleigh Morgan,聽Chengyang Liu,聽Jonathan Schug,聽Jinping Liu,聽Minghui Wu,聽Daniel Traum,聽Ayano Kondo,聽Catherine L. May,聽Naomi Goldman,聽Wenliang Wang,聽Michael Feldman,聽Jason H. Moore,聽Alberto S. Japp,聽Michael R. Betts,聽the HPAP Consortium,聽Robert B. Faryabi,聽Ali Naji,聽Klaus H. Kaestner聽&聽Golnaz Vahedi</p> </div> </div> <div class="post-single animated fadeInUpShort clear"> <div class="content-block"> <p class="heading-title"><strong><a href="https://pubmed.ncbi.nlm.nih.gov/34731614/" target="_blank" rel="noopener">Single-cell analysis of the human pancreas in type 2 diabetes using multi-spectral imaging mass cytometry. </a></strong><span class="authors-list-item ">Minghui Wu<span class="comma">,聽</span></span><span class="authors-list-item ">Michelle Y Y Lee<span class="comma">,聽</span></span><span class="authors-list-item ">Varun Bahl<span class="comma">,聽</span></span><span class="authors-list-item ">Daniel Traum<span class="comma">,聽</span></span><span class="authors-list-item ">Jonathan Schug<span class="comma">,聽</span></span><span class="authors-list-item ">Irina Kusmartseva<span class="comma">,聽</span></span><span class="authors-list-item ">Mark A Atkinson<span class="comma">,聽</span></span><span class="authors-list-item ">Guanjie Fan<span class="comma">,聽</span></span><span class="authors-list-item ">HPAP Consortium<span class="semicolon">;聽</span></span><span class="authors-list-item ">Klaus H Kaestner.聽</span></p> </div> </div> <div class="post-single animated fadeInUpShort clear"> <div class="content-block"> <p class="article-title"><strong><a href="https://www.jci.org/articles/view/143655" target="_blank" rel="noopener">Temporal manipulation of Cdkl5 reveals essential postdevelopmental functions and reversible CDKL5 deficiency disorder鈥搑elated deficits</a>. </strong>Barbara Terzic,聽M. Felicia Davatolhagh, Yugong Ho,聽Sheng Tang,聽Yu-Ting Liu,聽Zijie Xia,聽Yue Cui,聽Marc V. Fuccillo, and聽Zhaolan Zhou.</p> </div> </div> <div class="post-single animated fadeInUpShort clear"> <div class="content-block"> <p><strong><a href="https://www.gastrojournal.org/article/S0016-5085(21)03480-6/fulltext" target="_blank" rel="noopener">Highly multiplexed image analysis of intestinal tissue sections in patients with inflammatory bowel disease.</a></strong> Ayano Kondo, Siyuan Ma, Michelle Y.Y. Lee, Vivian Ortiz, Daniel Traum, Jonathan Schug, Benjamin Wilkins, Natalie A. Terry, Hongzhe Lee, Klaus H. Kaestner</p> </div> </div> <div class="post-single animated fadeInUpShort clear"> <div class="content-block"> <p class="article-header__title"><strong><a href="https://www.cell.com/developmental-cell/fulltext/S1534-5807(21)00355-5?rss=yes" target="_blank" rel="noopener">Cochlear supporting cells require GAS2 for cytoskeletal architecture and hearing</a></strong>. Tingfang Chen, Alex M. Rohacek, Matthew Caporizzo, Amir Nankali, Jeroen J. Smits, Jaap Oostrik, Cornelis P. Lanting, Erdi K眉c眉k, Christian Gilissen, Jiddeke M. van de Kamp, Ronald J.E. Pennings, Staci M. Rakowiecki, Klaus H. Kaestner, Kevin K. Ohlemiller, John S. Oghalai, Hannie Kremer, Benjamin L. Prosser, Douglas J. Epstein<i class="icon-gizmo-person faded" aria-hidden="true"></i></p> </div> </div> </div> <div class="button-wrap animated fadeInUpShort"> <a href="https://genetics.med.upenn.edu/category/publications/" class="btn small blue">Read More</a> </div> </aside> </div> </section> <!--End Announcements / Publications--> <!--Twitter / In the News--> <section class="twitter-news-wrap clear"> <div class="inner-container the-content animatedParent animateOnce clear"> <div class="in-the-news"> <div class="title animated fadeInRightShort"> <h3>In the News</h3> </div> <div class="list clear"> <div class="post-single animated fadeInUpShort clear"> <div class="content-block"> <div class="title"><a href="https://genetics.med.upenn.edu/penn-medicine-news-penn-commentary-highlights-potential-for-existing-drugs-like-statins-as-promising-covid-19-treatments/">Penn Medicine News – Penn Commentary Highlights Potential for Existing Drugs Like Statins As Promising COVID-19 Treatments</a></div> <p>by Melissa Moody, Senior Science Communications Officer New data suggest statins as a potentially helpful class of drugs to fight COVID-19, and pointing to that study, two researchers in the Perelman School of Medicine at…</p> <div class="button-wrap"> <a href="https://genetics.med.upenn.edu/penn-medicine-news-penn-commentary-highlights-potential-for-existing-drugs-like-statins-as-promising-covid-19-treatments/" class="btn blue small">Read More</a> </div> </div> </div> <div class="post-single animated fadeInUpShort clear"> <div class="content-block"> <div class="title"><a href="https://genetics.med.upenn.edu/this-west-philly-neighborhood-had-been-struggling-to-rebuild-then-the-looting-started/">The Philadelphia Inquirer – Doctors Aiding Protesters</a></div> <p>by Aubrey Whelan,聽Justine McDaniel,聽Jason Laughlin聽and聽Maddie Hanna.聽 Elizabeth Bhoj and her husband sought to help people affected by tear gas or injuries – “It鈥檚 hard seeing people trying to find a voice who have had theirs…</p> <div class="button-wrap"> <a href="https://genetics.med.upenn.edu/this-west-philly-neighborhood-had-been-struggling-to-rebuild-then-the-looting-started/" class="btn blue small">Read More</a> </div> </div> </div> <div class="post-single animated fadeInUpShort clear"> <div class="content-block"> <div class="title"><a href="https://genetics.med.upenn.edu/ap-news-new-old-drug-may-offer-fresh-ways-to-fight-heart-disease/">AP News – New, old drugs may offer fresh ways to fight heart disease</a></div> <p>By Marilynn Marchione Novel drugs may offer fresh ways to reduce heart risks beyond the usual medicines to lower cholesterol and blood pressure. One new study found that heart attack survivors benefited from a medicine…</p> <div class="button-wrap"> <a href="https://genetics.med.upenn.edu/ap-news-new-old-drug-may-offer-fresh-ways-to-fight-heart-disease/" class="btn blue small">Read More</a> </div> </div> </div> </div> <div class="button-wrap animated fadeInUpShort"> <a href="https://genetics.med.upenn.edu/category/in-the-news/" class="btn small red">View All</a> </div> </div> <div class="twitter-block"> <h3>Twitter</h3> <!-- Custom Twitter Feeds by Smash Balloon --> <div id="ctf" class=" ctf ctf-type-usertimeline ctf-rebranded ctf-feed-1 ctf-styles ctf-list ctf-regular-style" data-ctfshortcode="{"feed":1}" data-ctfdisablelinks="false" data-ctflinktextcolor="#" data-header-size="small" data-feedid="1" data-postid="16" data-feed="1" data-ctfintents="1" data-ctfneeded="3"> <div id="ctf" class="ctf"> <div class="ctf-error"> <div class="ctf-error-user"> Twitter feed is not available at the moment. </div> </div> </div> <div class="ctf-tweets"> </div> </div> </div> </div> </section> <!--End Twitter / In the News--> <!--End loop through the rows of data--> </div> </main> <!--End Content--> </div> <!--End Page--> <footer class="clear"> <!--Footer Content--> <section class="footer-main clear"> <div class="columns-wrap clear"> <div class="map-info" style="background-image: url('https://genetics.med.upenn.edu/wp-content/blogs.dir/66/files/sites/66/2020/02/footer-bg.jpg');"> <div class="trans-bg clear"> <div class="map-info-wrap"> <div class="map"></div> <div class="info"><p>Department of Genetics<br /> Perelman School of Medicine<br /> Clinical Research Building 500<br /> 415 Curie Blvd.<br /> University of Pennsylvania<br /> Philadelphia, PA 19104</p> </div> </div> </div> </div> <div class="search-wrap the-content"> <div class="search clear"> <h4>Search</h4> <form role="search" method="get" id="searchform" class="searchform" action="https://genetics.med.upenn.edu/"> <div class="search-fields"> <input type="text" value="" name="s" id="s" placeholder="Search Penn Genetics..." /> <button type="submit" class="search-submit" title="Search"><i class="fa fa-search" aria-hidden="true"></i></button> </div> </form> </div> <div class="social clear"> <h4>Follow Us</h4> <ul> <li> <a href="https://twitter.com/PennGenetics" target="_blank" title=""> <div class="social-icon"> <i class="fab fa-twitter" aria-hidden="true"></i> </div> </a> </li> </ul> </div> </div> </div> <!--Copyright--> <div class="copyright clear"> <div>Copyright © 2024</div> <div><p>The Trustees of the University of Pennsylvania. 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