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Poster Titles - PEGS Boston Summit
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data-sf-element="Column 1" data-placeholder-label="Column 1"> <div > <div class="sf-Long-text" ><h1 class="page-title">2025 POSTER PRESENTATIONS COMING IN APRIL<b style="background-color:transparent;color:inherit;font-size:inherit;text-align:inherit;text-transform:inherit;white-space:inherit;word-spacing:normal;caret-color:auto;"></b><b style="background-color:transparent;color:inherit;font-size:inherit;text-align:inherit;text-transform:inherit;white-space:inherit;word-spacing:normal;caret-color:auto;"></b><b></b></h1><b></b><p><i></i><i></i></p><p><i>Here is a reminder of the 2024 Poster Presentations</i><i></i></p><p><b style="background-color:transparent;color:inherit;font-family:inherit;font-size:inherit;text-align:inherit;text-transform:inherit;word-spacing:normal;caret-color:auto;white-space:inherit;"><u>POSTER SESSION A: Monday – Tuesday (morning)</u></b><b style="background-color:transparent;color:inherit;font-family:inherit;font-size:inherit;text-align:inherit;text-transform:inherit;word-spacing:normal;caret-color:auto;white-space:inherit;"> </b><br /></p><p><b>A001: Selective IL-21 and IFN-a2 Immunocytokines Engineered Using the AlphaSeq Platform</b>, <i>Presented by Jeffrey A., A-Alpha Bio</i></p><p><b>A002: Design and Apply EGFR/c-Met/c-Met Trispecific Antibody for Cancer Therapy</b>, <i>Presented by Yue L., Ab Therapeutics, Inc</i></p><p><b>A003: Discovery of GPCR Antibody Agonists Using Functional Selection and Machine Learning</b>, <i>Presented by Lauren S., Abalone Bio</i></p><p><b>A004: Nanomolar VHH Binders of PD-L1 and Other Therapeutic Targets from the AbNano™ VHH Naive Library</b>, <i>Presented by Sam S., Abcore, a Fortis Life Sciences Company</i></p><p><b>A005: A Native Multi-Dimensional Monitoring Workflow for At-Line Characterization of mAb Titer, Size, Charge, and Glycoforms Heterogeneities in Cell Culture Supernatant</b>, <i>Presented by Wayne H., Agilent Technologies, Inc.</i></p><p><b>A006: XrossXeven: AI-Powered GPCR Protein Antigen De Novo Design</b>, <i>Presented by Patrick D., Ailux Biologics by XtalPi</i></p><p><b>A007: Harnessing IL-18BP Modulation for Enhanced Cancer Immunotherapy: Antibody Engineering Strategies and Therapeutic Potential</b>, <i>Presented by Li Z., Alector, Inc.</i></p><p><b>A008: 2D NMR for Higher Order Structure Assessment of Forced Degraded Monoclonal Antibodies</b>, <i>Presented by Sih Yao C., Amgen, Inc.</i></p><p><b>A009: Bridging the Synthesis Gap: Automated Fast-Flow Peptide Synthesis (AFPS) Enables High-Fidelity Production of Difficult-to-Express Proteins</b>, <i>Presented by Kyuto T., Amide Technologies, Inc.</i></p><p><b>A010: Quantification of the Antigen Density Activation Threshold for Targeted Immunotherapeutics</b>, <i>Presented by Lotta H., Antibody Analytics</i></p><p><b>A011: Antibody Humanization with Predictive Design</b>, <i>Presented by Sridhar G., ATUM</i></p><p><b>A012: Rapid Multiparametric Optimization of Antibody Using Yeast Autonomous Hypermutation</b>, <i>Presented by Jake H., Aureka Biotechnologies, Inc.</i></p><p><b>A013: Novel Signal Peptide Screening-Based Platform for Optimization of Recombinant Protein Production</b>, <i>Presented by Tero-Pekka A., Avenue Biosciences, Inc.</i></p><p><b>A014: Hypercell® Platform: High-Throughput Secretion-Based Single Cell Sorter and Its Application in Drug Discovery</b>, <i>Presented by Kyle N., Bioelectronica Corporation</i></p><p><b>A015: Cloning and Expression of a Multi-Subunit Protein Using the MultiBacMam Expression System</b>, <i>Presented by Timothy G., Biogen</i></p><p><b>A016: A Proven and Reliable Alpaca VHH Antibody Discovery Platform</b>, <i>Presented by Haoming Z., Biointron</i></p><p><b>A017: TrailBlazer: A Rapid Modular Antibody Assembly Platform</b>, <i>Presented by Miao L., Bio-Rad Laboratories</i></p><p><b>A018: Pioneer Platform: A Novel Biotherapeutic Antibody Discovery Platform</b>, <i>Presented by Francisco Y., Bio-Rad Laboratories</i></p><p><b>A019: Preclinical Characterization of a Highly Differentiated Pan-Allele Anti-SIRPa Antibody BSI-082 that Targets the Myeloid Immune Checkpoint</b>, <i>Presented by Mingjiu C., Biosion USA, Inc.</i></p><p><b>A020: Biotherapeutics for Animal Health</b>, <i>Presented by Ivan S., Boehringer Ingelheim Vetmedica GmbH</i></p><p><b>A021: Ultra-Large Scale Biomanufacturing in the Fourth Industrial Wave</b>, <i>Presented by Chi-Ming Y., Boston Institute of Biotechnology</i></p><p><b>A022: Accelerating Functional Antibody Therapeutics Development with Bruker's Beacon Optofluidic System</b>, <i>Presented by Leqian L., Bruker Scientific</i></p><p><b>A023: Relative Affinity Ranking of Recombinant Antigen-Specific Hits with Bruker’s Beacon Optofluidic System</b>, <i>Presented by Vincent P., Bruker Scientific</i></p><p><b>A024: Three Case Studies of HPLC-MALS and ddPCR Analytical Platform Methods to Support Biopharmaceutical Drug Products</b>, <i>Presented by Felipe B., Cambrex</i></p><p><b>A025: Large-Scale Characterization of Drug Candidates Against Transmembrane Receptors Using HT-SPR</b>, <i>Presented by Josh E., Carterra, Inc.</i></p><p><b>A026: MagDots: A Nanoparticle that Is Both Fluorescent and Magnetic for the Single Label Enrichment of Targeted Cells in Yeast Display Libraries</b>, <i>Presented by Mythreyi U., Core Quantum Technologies</i></p><p><b>A027: Discovery of High-Affinity Anti-Glycan Antibodies Using Glycoengineered Bacterial Vesicles</b>, <i>Presented by Weiyao W., Cornell University</i></p><p><b>A028: Immuno-STATs for Targeted Depletion of B Cells in Autoimmune Diseases</b>, <i>Presented by Nitin K., Cue Biopharma</i></p><p><b>A029: myTXTL Cell-Free Expression of Antibodies and Antibody Fragments</b>, <i>Presented by Nathan G., Daicel Arbor Biosciences</i></p><p><b>A030: Epitope Mapping Case Studies by Deep Mutational Scanning</b>, <i>Presented by Tiphanie P., Deeptope</i></p><p><b>A031: Mammalian Display Technology Platform for Therapeutic Lead Antibody Engineering</b>, <i>Presented by Donghui M., DIMA Biotechnology</i></p><p><b>A032: Generative AI Based Affinity Engineering of TCRs for Potent Soluble T Cell Engagers</b>, <i>Presented by Ross R., Etcembly</i></p><p><b>A033: Streamlined Antibody Drug Conjugate Production: A Holistic Approach to ADC Manufacturing</b>, <i>Presented by Dragan M., Eurofins CDMO Alphora, Inc.</i></p><p><b>A034: Advancing Therapeutics Targeting Inflammatory Cytokines with Functional Cell-Based Assays</b>, <i>Presented by Debatri C., Eurofins DiscoverX</i></p><p><b>A035: High Throughput Approaches for In Silico Developability, Production and Characterization in Antibody Discovery</b>, <i>Presented by Catia P., FairJourney Biologics SA</i></p><p><b>A036: Antibody Discovery and Characterization: A Multidimensional Approach for Next-Generation Therapeutics</b>, <i>Presented by Joao S., FairJourney Biologics SA</i></p><p><b>A037: Small Molecule Interactions with Membrane Proteins Using Flow Induced Dispersion Analysis</b>, <i>Presented by Mark K., Fida Biosystems</i></p><p><b>A038: Mammalian Display for Antibody Discovery</b>, <i>Presented by Richard M., Fusion Antibodies</i></p><p><b>A039: Future Fields' EntoEngine™: Revolutionizing Recombinant Protein Production with Transgenic Drosophila</b>, <i>Presented by Ela D., Future Fields</i></p><p><b>A040: Artificial Intelligence Automates the Assignment of Biacore SPR and Octet BLI Kinetic Binding Profiles for a Faster Characterization of Lead Series</b>, <i>Presented by Eriberto N., Genedata AG</i></p><p><b>A041: Fast and Efficient Evaluation of the Impact of IgG Fc N-Glycan Structure on Effector Functions</b>, <i>Presented by Camilla S., Genovis</i></p><p><b>A042: The FORGE™ Engine Discovers Novel Tissue-Targeting Moieties for Delivery of Antisense Oligonucleotides to Muscle, Adipose and Brain</b>, <i>Presented by Maya L., Gensaic</i></p><p><b>A043: Treatment of Solid Tumors with Antibody Drug Conjugates Targeting Aberrant O-Glycoproteins</b>, <i>Presented by Nisha S., GO Therapeutics</i></p><p><b>A044: Antibody CDR Design by Ensembling Inverse Folding with Protein Language Models</b>, <i>Presented by Diego D., GSK</i></p><p><b>A045: Addressing the Antibody Germline Bias and Its Effect on Language Models for Improved Antibody Design</b>, <i>Presented by Tobias O., GSK</i></p><p><b>A046: Anti-Inflammatory Clearance of Aß by a Chimeric Gas6 Fusion Protein</b>, <i>Presented by Gyunam J., Illimis Therapeutics</i></p><p><b>A047: High-Sensitive Immunopeptidomics for Identification of (Neo)antigens and Development of High-Efficient Biotherapeutics</b>, <i>Presented by Elise P., ImmuneSpec</i></p><p><b>A048: New Humanized Mouse as High-Performance Fully Human Antibody Generator with More Potent Anti-hTIGIT Antibody Identified</b>, <i>Presented by Yu Z., Immunocan</i></p><p><b>A049: Functional Evaluation of Immuno-Oncology Drug Candidates in Customized Bioassays</b>, <i>Presented by Sofie P., ImmunXperts, a Q2 Solutions Company</i></p><p><b>A050: Development of Cross-Reactive Immunological Material (CRIM) Assay for ENPP1 Deficiency</b>, <i>Presented by Di C., Inozyme Pharma</i></p><p><b>A051: High Throughput Development of High-Affinity Fabs and VHH Using Minimalistic Libraries</b>, <i>Presented by Andre T., Institute for Protein Innovation</i></p><p><b>A052: Preclinical Safety Assessment for Specificity of Biotherapeutics Using the Membrane Proteome Array</b>, <i>Presented by Rachel F., Integral Molecular</i></p><p><b>A053: CCR8 Antibody Drug Conjugates: Targeting Regulatory T Cells for Tumor Sensitization</b>, <i>Presented by Sharon W., Integral Molecular</i></p><p><b>A054: Early Cell Lines Development for Production of Therapeutic Molecules</b>, <i>Presented by Carlos S., FairJourney Biologics SA</i></p><p><b>A055: Predicting the Clinical Pharmacokinetics of Candidate Therapeutic Antibodies</b>, <i>Presented by Kaitlyn G., Jackson Laboratory</i></p><p><b>A056: Translational Humanized Models for Immunotherapy Drug Development</b>, <i>Presented by Mike K., Jackson Laboratory</i></p><p><b>A057: Revolutionizing Bispecific Antibody Manufacturing via Transposase-Mediated Insertions</b>, <i>Presented by Mohammad H., Johnson & Johnson Innovative Medicine</i></p><p><b>A058: Increasing Therapeutic Antibody Production via Double Gene Expression Cassettes</b>, <i>Presented by Annabel J., Johnson & Johnson Innovative Medicine</i></p><p><b>A059: GPCR VLPs and Nanodiscs for Drug Discovery</b>, <i>Presented by Jia C., Kactus</i></p><p><b>A060: Cell-Free Spectroscopy Techniques for Antibody/Antigen Production and Screening</b>, <i>Presented by Shakiba N., Lawrence Livermore National Laboratory</i></p><p><b>A061: Pandemic Preparedness with ALiCE® - Scalable Eukaryotic Cell-Free Protein Synthesis Enables Ultra-Rapid Threat Response</b>, <i>Presented by Malene L., LenioBio GmbH</i></p><p><b>A062: Rapid Screening and Scaled Manufacture of Immunogenic Virus-Like Particles in a Tobacco BY-2 Cell Free Protein Synthesis System</b>, <i>Presented by James N., LenioBio GmbH</i></p><p><b>A063: Next Generation Binding: Measuring Cell Avidity to Fully Characterize Cell-Cell Interactions and Understand Mechanism of Action for Cellular Therapies</b>, <i>Presented by Russell M., LUMICKS</i></p><p><b>A064: 2MW3311: Combating Autoimmune Diseases by Depleting Pathogenic T Cells via Anti-CXCR6</b>, <i>Presented by Hsueh L., Mabwell Therapeutics</i></p><p><b>A065: PHAME - Therapeutic Antibodies Against Intractable Drug Targets</b>, <i>Presented by Konstantin H., Max Planck Institute for Medical Research</i></p><p><b>A066: Automated Workflow for Rank-Ordering Variants by Affinity Within a Yeast Surface Display Library</b>, <i>Presented by Derek V., Metaphore Biotechnologies, Inc.</i></p><p><b>A067: Enhancing Therapeutic Efficacy of Monoclonal Antibodies with Zinc Finger Nuclease-Mediated Knockout of the FUT8 Gene in CHOZN® Cell Lines</b>, <i>Presented by Amber P., MilliporeSigma</i></p><p><b>A068: CAR-T Cells Based on a TCR Mimic Nanobody Targeting HPV16 E6 for Treating Cervical Cancer</b>, <i>Presented by Zhijian D., National Institutes of Health, National Cancer Institute</i></p><p><b>A069: Direct Solubilization to Produce Active Neuropathy Target Esterase, an ER Membrane Associated Protein, for Functional and Structural Studies</b>, <i>Presented by Yi H., National Institutes of Health, National Heart, Lung, and Blood Institute</i></p><p><b>A070: Single Domain Antibodies as Potent and Selective Inhibitors of Carbonic Anhydrase IX</b>, <i>Presented by Majida E., National Research Council Canada</i></p><p><b>A071: Development of a ‘Switchable’ Yeast for Antibody Discovery</b>, <i>Presented by Gregory B., Neochromosome, Inc.</i></p><p><b>A072: Automated Purification of Proteins from NEBExpress Cell-free E. coli Protein Synthesis Reactions Using NEBExpress Ni-NTA Magnetic Beads and a Magnetic Particle Processor</b>, <i>Presented by Jackson B., New England Biolabs</i></p><p><b>A073: Systematic Structural Evaluation of Polycystin Variants by CryoEM</b>, <i>Presented by Orhi E., Northwestern University</i></p><p><b>A074: Numaswitch – The Revolution of Peptein Production</b>, <i>Presented by Roxann G., NUMAFERM GmbH</i></p><p><b>A075: Two-Cell Assays for High-Throughput Screening of Membrane-Bound Protein Targets</b>, <i>Presented by Ronald R., Partillion Bioscience</i></p><p><b>A076: HiBiT: A Tiny Tag to Assess MOA-Based CAR-T Cell Potency</b>, <i>Presented by Julia G., Promega Corporation</i></p><p><b>A077: Development of a MoA-Based Bioassay Platform for Safe and Rapid Assessment of Virus Neutralization</b>, <i>Presented by Kai H., Promega Corporation</i></p><p><b>A078: Development of Bioluminescent No-Wash Fc Gamma Receptor Binding Immunoassay to Guide the Development of Antibody Therapeutics</b>, <i>Presented by Alissa K., Promega Corporation</i></p><p><b>A079: RaGene: AI-Powered Gene Optimization Platform Maximizes Yield and Enhances Protein Stability</b>, <i>Presented by Wafaa A., Proteinea, Inc.</i></p><p><b>A080: Salipro® Nano-Membrane Particles for the Discovery and Characterization of Antibodies Against Challenging Membrane Protein Targets</b>, <i>Presented by Peter J., Salipro Biotech</i></p><p><b>A081: Discovery of Novel Therapeutics Against GPCRs, Ion Channels and Transporters Using the Salipro Platform</b>, <i>Presented by Sara B., Salipro Biotech AB</i></p><p><b>A082: Design and Screening of FcyRIIb Selective Fc Domains to Enhance PD-1 Agonism and Treat Autoimmunity</b>, <i>Presented by Samuel P., Seismic Therapeutic</i></p><p><b>A083: Discovery and Characterization of FcγRIIb Selective Antibodies to Enhance PD-1 Agonism and Treat Autoimmunity</b>, <i>Presented by Ishan S., Seismic Therapeutic</i></p><p><b>A084: Utilizing a Cancer-Specific Peptide to Deliver a Novel Immunotherapy for the Treatment of Cancer</b>, <i>Presented by Shelby K., SRI International</i></p><p><b>A085: T Cell Targeting with PD-1-Selective Immune Cell Engagers Based on GlycoConnect™ Technology Show Favorable Efficacy and Tolerability</b>, <i>Presented by Remon V., Synaffix, A Lonza Company</i></p><p><b>A086: Antigens for Integral Membrane Protein Antibody Discovery</b>, <i>Presented by Olivia E., Takeda Pharmaceuticals</i></p><p><b>A087: Potent Antibody Discovery Using Yeast Display and Human IgG Transgenic Mice</b>, <i>Presented by Leike L., Takeda Pharmaceuticals</i></p><p><b>A088: Membrane Protein Chimeric and Truncated Cell Line Generation for Biologics Screening</b>, <i>Presented by Dongyun W., Takeda Pharmaceuticals</i></p><p><b>A089: Antibody Labeling Reagents to Rapidly Screen for Binding, Internalization, and Degradation of Biologics and Antibody Drug Conjugates</b>, <i>Presented by Ryan H., Thermo Fisher Scientific</i></p><p><b>A090: Optimizing Expression and Purification Workflows for Membrane Proteins</b>, <i>Presented by Matt M., Thermo Fisher Scientific</i></p><p><b>A091: Synthetic Biology Solutions to Accelerate Antibody Development</b>, <i>Presented by Claudia C., Thermo Fisher Scientific GENEART GmbH</i></p><p><b>A092: TRIV-509, a Dual-Specific Antibody Targeting KLK5 and KLK7 Proteases, Binds at the Active Site with High Affinity and Inhibits Proteolytic Activity</b>, <i>Presented by Brantley H., Triveni Bio</i></p><p><b>A093: Optimization of a Glucagon-Like Peptide 1 Receptor Antagonist Antibody for the Treatment of Hyperinsulinism</b>, <i>Presented by Lindsay D., Twist Bioscience</i></p><p><b>A094: Discovery and Optimization of Novel Complement Component 5a Receptor 1 Antagonistic Antibodies</b>, <i>Presented by Crystal S., Twist Bioscience</i></p><p><b>A095: Journey Towards Advancing Cancer Immunotherapy via HLA-G Pathway Modulation with Anti-HLA-G Antibody (UCB4594)</b>, <i>Presented by Ruth M., UCB</i></p><p><b>A096: Innovation in ADC Development: Unleashing the Potential of In Vivo Phage Display Selections and Rabbit Derived VL Single-Domain Antibodies to Develop Highly Specific and Potent ADC´s Against Novel Targets</b>, <i>Presented by Frederico AS., University of Lisbon</i></p><p><b>A097: Sequence-Developability Mapping of Affibody and Fibronectin Paratopes via Library-Scale Variant Characterization</b>, <i>Presented by Gregory N., University of Minnesota</i></p><p><b>A098: Learning the Rules of T Cell Receptor Cross-Reactivity with Yeast Display</b>, <i>Presented by Dan H., University of Oxford</i></p><p><b>A099: Cationic Peptide Anchor-Mediated Binding to Tumor Extracellular Matrix Improves Intratumoral Retention of Agonist CD40 Antibody</b>, <i>Presented by Yuting P., University of Texas at Austin</i></p><p><b>A100: Discovery of High Affinity Functional Antibodies Specific for CXCR5 and Other Multi-Pass Membrane Proteins</b>, <i>Presented by Leslie B., Vaccinex</i></p><p><b>A101: Novel Bispecific Antibodies Effectively Enhance Therapeutic Efficacy in Thyroid Eye Disease (TED) by Targeting the Molecular Pathway and Disrupting the Biological Crosstalk Associated with the Condition</b>, <i>Presented by Jing L., VelaVigo</i></p><p><b>A102: Optimizing Bispecific Antibody Production: Strategies for Improved Purity and Yield</b>, <i>Presented by Sundee D., WuXi Biologics</i></p><p><b>A103: Exploring Digital Twin Technology in Improving Surgical Outcomes</b>, <i>Presented by Rakan A., Johns Hopkins University</i></p><div><b>A104: Isolation and Characterization of Promising Anti-PD-1 Antibodies to Treat Cancer</b>, <i>Presented by Frida RV., Unidad de Desarrollo e Investigación en Bioprocesos (UDIBI)</i></div><p> </p><p><b></b><b> </b></p><p><b><u>POSTER SESSION B: Tuesday (afternoon) – Wednesday</u></b><b> </b></p><p><b>B001: Real-Time Kinetics on Cells and Further Analytical Tools to Avoid the Translational Gap</b>, <i>Presented by Vera M., 2bind GmbH</i></p><p><b>B002: Defining the Biophysical Design Parameters for Logic-Gated CAR-T Systems</b>, <i>Presented by Alexander P., A2 Biotherapeutics, Inc.</i></p><p><b>B003: Biophysical Methodologies for the QC of Abcam Rabbit Monoclonal Antibodies (RabMAb®) and Proteins</b>, <i>Presented by Deborah ML., Abcam</i></p><p><b>B004: PSMA x CD3 T-Cell Engagers with Potent Cytotoxicity and Low Cytokine Release</b>, <i>Presented by Raffi T., AbCellera</i></p><p><b>B005: An AI-Assisted Selective CD16A-Targeting NK Cell Engager Showed Superior Anti-Tumor Activity In Vitro</b>, <i>Presented by Jessica J., Ailux Biologics by XtalPi</i></p><p><b>B006: Efficient Production of VHHs Containing Non-Canonical Amino Acids by Corynex®</b>, <i>Presented by Yumi N., Ajinomoto Co., Inc.</i></p><p><b>B007: Establishment of Human Rare Disease Organoid Models and Development of Microphysiological System</b>, <i>Presented by Jae Hee B., Asan Medical Center</i></p><p><b>B008: Generation of Sarconoids from Angiosarcoma Patients as a Systematic-Based Rational Approach to Treatment</b>, <i>Presented by Da Jung J., Asan Medical Center</i></p><p><b>B009: Predicting HCP Levels in Therapeutic Protein Products</b>, <i>Presented by Jared D., AstraZeneca</i></p><p><b>B010: Leap-In Transposases® - A New Paradigm of Cell Line Development</b>, <i>Presented by Claes G., ATUM</i></p><p><b>B011: Optimized Recombinant Antibody Production: A Comprehensive End-to-End Solution by GENEWIZ</b>, <i>Presented by Jung D., Azenta Life Sciences</i></p><p><b>B012: Investigating Factors Impacting TLR7 Immunostimulatory ADC Pharmacokinetics and Pharmacodynamics</b>, <i>Presented by Samantha B., Binghamton University: The State University of New York</i></p><p><b>B013: Implementing Design of Experiment (DOE) in ADA Optimization for Targeted Therapeutics</b>, <i>Presented by Matthew B., BioAgilytix Labs</i></p><p><b>B014: Development of High Throughput Single-B Cell Antibody Discovery Platform</b>, <i>Presented by Huanyi Y., Biointron</i></p><p><b>B015: Computationally Designed Multibodies: Binding Two Unrelated Targets with One, Symmetrical Standard Human IgG Antibody</b>, <i>Presented by Yael D., Biolojic Design</i></p><p><b>B016: Accurate Profiling of Full-Length Fv in Highly Homologous Antibody Libraries Using UMI-Tagged Short Reads</b>, <i>Presented by Yair F., Biolojic Design</i></p><p><b>B017: Rapid Generation of Bispecific Antibodies for High Throughput Screening with SpyLock Technology</b>, <i>Presented by Erika H., Bio-Rad Laboratories</i></p><p><b>B018: Comprehensive Analysis and Characterization of Glycan Pairing in Therapeutic Antibodies and Fc-Containing Biotherapeutics</b>, <i>Presented by Maximilian M., Boehringer Ingelheim Pharma GmbH & Co. KG</i></p><p><b>B019: Throughput Meets Flexibility: The Next Generation Multiplexing SPR for Efficient Therapeutic Protein Discovery and Development</b>, <i>Presented by Matthew P., Bruker Scientific</i></p><p><b>B020: HT-SPR Evaluation of Fc Gamma Receptor Binding Using Carterra LSA-XT</b>, <i>Presented by Maria M., Carterra, Inc.</i></p><p><b>B021: Digital Control of Expression for Rapid, High-Titer Production of Complex Products in CHO Cells</b>, <i>Presented by Chad H., Catalent Biologics</i></p><p><b>B022: Exploring the Dynamic Changes of Nucleic Acids to Evaluate the Effect of Protonated Nucleotides on Structure and Binding</b>, <i>Presented by Stefania E., Chemical Computing Group</i></p><p><b>B023: Immuno-STATs (ISTs): A Novel and Unique T-Cell Engager Platform for the Treatment of Immuno-Oncology and Autoimmune Diseases</b>, <i>Presented by Ahmet V., Cue Biopharma</i></p><p><b>B024: Antibody Analyses with Biacore™ System - Convenient, Sensitive, Versatile</b>, <i>Presented by Eric R., Cytiva</i></p><p><b>B025: Modulation of Antibodies' Fc Fragment Interaction with Fc Receptors by Deep Mutational Scanning</b>, <i>Presented by Fabien Q., Deeptope</i></p><p><b>B026: Comprehensive Cell-Based Assays for Characterization and Development of Agonistic Antibodies as Therapeutics for Cancer and Autoimmune Diseases</b>, <i>Presented by Gaurav A., Eurofins DiscoverX</i></p><p><b>B027: FcRN Binding Assessment of IgG Fc Variants: A 360° View with Affinity, Kinetics and In Vitro Testing</b>, <i>Presented by Silvestre L., FairJourney Biologics SA</i></p><p><b>B028: Applying Flow Induced Dispersion Analysis for In-Solution Binding Kinetics</b>, <i>Presented by </i><i>Henrik J.</i><i>, Fida Biosystems</i></p><p><b>B029: Model Acetylcholinesterase-Fc Fusion Glycoprotein Biotechnology System for the Manufacture of an Organophosphorus Toxicant Bioscavenging Countermeasure</b>, <i>Presented by Tylee H., Food and Drug Administration</i></p><p><b>B030: Development of a Chemically Defined Growth Medium Specifically Designed for CHO DG44 Cells</b>, <i>Presented by</i><i> Ociel F.</i><i>, FUJIFILM Irvine Scientific</i></p><p><b>B031: Advancing Antibody Therapeutics: Leveraging Biolayer Interferometry for Label-Free Camelid Nanobody Quantitation and Kinetics Screening</b>, <i>Presented by</i><i> Vivienne L.</i><i>, Gator Bio</i></p><p><b>B032: NeoMab™: A Novel Platform for Fully Human Therapeutic Antibody Development</b>, <i>Presented by Jun W., GemPharmatech</i></p><p><b>B033: Structure of the Wnt-Frizzled-LRP6 Initiation Complex Reveals the Basis for Coreceptor Discrimination</b>, <i>Presented by Sunhee H., Genentech</i></p><p><b>B034: Leveraging Multiplexed MAPPs Data for In Silico and In Vitro Immunogenicity Risk Assessment</b>, <i>Presented by Prasad P., Generate Biomedicines</i></p><p><b>B035: Fully Automated TNFα Epitope Mapping with Benchtop Hydroxyl Radical Protein Footprinting Technology</b>, <i>Presented by Jiana D., GenNext Technologies, Inc.</i></p><p><b>B036: Enzymatic Tools for Generation of Homogeneous Antibody Fragments – From High-Throughput Screening to Manufacturing Scale</b>, <i>Presented by Laurent R., Genovis</i></p><p><b>B037: Integrated Solutions for Antibody Drug Development: A Comprehensive Approach with GenScript</b>, <i>Presented by Amanda G., GenScript USA, Inc.</i></p><p><b>B038: Design and Engineering of Multi-Specific Antibody and Its Therapeutic Applications for AI Drug Discovery</b>, <i>Presented by Hengtai L., GenScript USA, Inc.</i></p><p><b>B039: Automated High Throughput Purification Platform for Small Scale Expression in E.coli</b>, <i>Presented by Jane Z., GSK</i></p><p><b>B040: Advanced High Throughput Particle Analysis: Characterizing Protein Therapeutic Stability from Developability Assessment to Release</b>, <i>Presented by Steven L., Halo Labs</i></p><p><b>B041: Fc Engineering to Enable Subcutaneous Antibody Formulation and Beyond</b>, <i>Presented by Yasmin S., Illinois Institute of Technology</i></p><p><b>B042: Early Unwanted Immunogenicity Risk Assessment of Biotherapeutics</b>, <i>Presented by Chloe A., ImmunXperts, a Q2 Solutions Company</i></p><p><b>B043: Enhanced Plasmid Production: Achieving a 21-Fold Increase in Plasmids</b>, <i>Presented by Andrew M. and Sam E., INFORS HT & Thomson Instrument Company</i></p><p><b>B044: DNA Nanotechnology Used to Rapidly Screen and Modulate T-Cell Engagement Using Hybrid DNA-Protein Analogs of Blinatumomab</b>, <i>Presented by Sabrine M., Institut National de la Recherche Scientifique - INRS</i></p><p><b>B045: Bispecific and Trispecific GPRC5D Antibodies with Potent Cell-Killing Activity Against Multiple Myeloma</b>, <i>Presented by Ross C., Integral Molecular</i></p><p><b>B046: Accelerating Antibody Discovery and Development to the Clinic with Proprietary Mammalian Display</b>, <i>Presented by Kothai P., Iontas Ltd.</i></p><p><b>B047: A Novel, Translational Platform to Assess the Efficacy and Toxicity of Bispecific Antibodies</b>, <i>Presented by Joshua S., Jackson Laboratory</i></p><p><b>B048: Higher Order Structure, Stability, and Similarity Assessment of VHH Antibodies Using CD Spectroscopy</b>, <i>Presented by Ai Y., JASCO Corporation</i></p><p><b>B049: Engineering Novel IgG Fc Glycosylation Sites for Bioconjugation</b>, <i>Presented by Zachary B., Johns Hopkins University</i></p><p><b>B050: Comparison of the Performance of Pharmalytes and AESLytes for Routine Capillary Isoelectric Focusing</b>, <i>Presented by Caleen D., Johnson & Johnson Innovative Medicine</i></p><p><b>B051: ATF N-1/N Stage Perfusion Platform Process Development Using mAb Producing CHO Cell Culture</b>, <i>Presented by Kevin H., JOINN Biologics US, Inc.</i></p><p><b>B052: Transforming Tumor Research: Engineering MHCs as Versatile Reagents</b>, <i>Presented by Manhee S., Kactus</i></p><p><b>B053: First Insights into Functionality of Cell-Free Produced Adalimumab in Comparison to Humira®</b>, <i>Presented by Ricarda F., LenioBio GmbH</i></p><p><b>B054: Accelerating Drug Development with Flexible, Scalable, Single-Cell Functional Profiling</b>, <i>Presented by Simon M., Lightcast Discovery Ltd.</i></p><p><b>B055: An Adaptor Platform Allows Selective CAR-T Cell Expansion by Cis-Targeting of Engineered Interleukin-2</b>, <i>Presented by Simone L., Ludwig Maximilians University</i></p><p><b>B056: Multiplexed Screening of 1000s of Brain Shuttle Designs In Vivo with Protein Barcoding to Engineer Blood-Brain Barrier Penetrating Therapeutics with Optimal Properties</b>, <i>Presented by Alex R., Manifold Biotechnologies, Inc.</i></p><p><b>B057: Anti-Idiotypic Antibody as Booster Vaccine Against Respiratory Syncytial Virus</b>, <i>Presented by Shreya M., Merck & Co., Inc.</i></p><p><b>B058: Scalable Transient Gene Expression in CHOZN® GS-/- Cells Using Thomson Optimum Growth® Flasks</b>, <i>Presented by Kelsey R., MilliporeSigma</i></p><p><b>B059: Integrating Cryo-EM into Therapeutic Discovery and Structural Toxicology</b>, <i>Presented by Nicole P., NanoImaging Services</i></p><p><b>B060: Predicting Biologics Developability: A Combinatorial Approach with Thermal and Colloidal Stability Measurements for Improved Assessments</b>, <i>Presented by Rebecca H., NanoTemper Technologies, Inc.</i></p><p><b>B061: Broadly Neutralizing Camel Nanobody J1B4 Against the S2 Subunit of SARS-CoV-2</b>, <i>Presented by Jessica H., National Institutes of Health, National Cancer Institute</i></p><p><b>B062: Novel Engineered T-Cells Targeting Glypican-2 Regress Antigen Low Neuroblastoma in Mice</b>, <i>Presented by Laura H., National Institutes of Health, National Cancer Institute</i></p><p><b>B063: Arsenal of Nanobodies Shows Broad-Spectrum Neutralization Against SARS-CoV-2 Variants of Concern In Vitro and In Vivo in Hamster Models</b>, <i>Presented by Martin R., National Research Council Canada</i></p><p><b>B064: NTxpress Platform Coupled with Hollow Fiber Bioreactors Can Be Leveraged to Produce Target Proteins</b>, <i>Presented by Robert J., Nature's Toolbox</i></p><p><b>B065: Robust nanoCLAMP Protein Ligands for Affinity Chromatography</b>, <i>Presented by Richard S., Nectagen, Inc.</i></p><p><b>B066: Rapid Method for Cell-Free Protein Synthesis (CFPS) from DNA or RNA Synthesized In Vitro</b>, <i>Presented by Paula M., New England Biolabs</i></p><p><b>B067: Characterization of Therapeutic Antibodies Using Digital SPR</b>, <i>Presented by Michael P., Nicoya Lifesciences</i></p><p><b>B068: Fully Human Heavy Chain Only Antibodies to BCMA Identified by NonaCarFx Platform</b>, <i>Presented by Jason N., Nona Biosciences</i></p><p><b>B069: Enhanced Brain Penetration and Neuronal Uptake Through Receptor-Mediated Transcytosis: Development of Fully Human Anti-TfR1 Heavy Chain Only Antibody Based Blood-Brain Barrier Shuttle Technology</b>, <i>Presented by Jiyong Z., Nona Biosciences</i></p><p><b>B070: Investigation of the Protein Sequence and Structural Determinants of Aggregation Resistance</b>, <i>Presented by Cydney M., Northwestern University</i></p><p><b>B071: Bioengineering of Site-Specific Antibody Labeling from Basic Research to Spatial Omics Platforms</b>, <i>Presented by Kai T., Oregon Health and Science University</i></p><p><b>B072: Co-Expression of MAGE-A3 and PD-L1 in Colon, Lung, and Bladder Cancers</b>, <i>Presented by Hailey G., Origene Technologies, Inc.</i></p><p><b>B073: Developability Assessment for Nonspecificity and Polyspecificity in High-Throughput Bead-Based Assays in Microplates</b>, <i>Presented by Sebastian G., PAIA Biotech GmbH</i></p><p><b>B074: A Novel Synthetic Receptor Changes CAR-T Cells into Superior Killers in Solid Tumors</b>, <i>Presented by Joe Z., Peter Maccallum Cancer Centre</i></p><p><b>B075: High Titers of ncAA-Incorporated Therapeutic Protein Candidates Produced in Pseudomonas fluorescens</b>, <i>Presented by Nathaniel H., Primrose Bio</i></p><p><b>B076: Ankyrons – Target Binding Reagents Beyond Antibodies</b>, <i>Presented by Olivia W., ProImmune, Inc.</i></p><p><b>B077: A Drug Development Platform for Protein Biologics that Integrates Production, Developability Assessment, Kinetic Profiling and High Resolution Cryo-EM and X-Ray Structural Determination</b>, <i>Presented by Joanna D., Proteros Biostructures GmbH</i></p><p><b>B078: Multiplex Measurement of Tumor Biomarkers Associated with Colorectal Adenocarcinoma Using Novel Sample Types</b>, <i>Presented by James R., R&D Systems, Inc., a Bio-Techne brand</i></p><p><b>B079: Structural Characterization of RNA and Detection of RNA-Ligand Binding Using Microfluidic Modulation Spectroscopy (MMS)</b>, <i>Presented by Valerie C., RedShift BioAnalytics, Inc.</i></p><p><b>B080: Development of a New Arrhenius Kinetics-Based Modeling Tool for Fast, Accurate and Robust Prediction of Long-Term Stability of Therapeutic Antibodies</b>, <i>Presented by Jiewei W., Regeneron Pharmaceuticals</i></p><p><b>B081: Gene Therapy Applications on LabChip GX II Touch: From pDNA QC to mRNA Characterization</b>, <i>Presented by James W., Revvity</i></p><p><b>B082: Sequence Variant Analysis to Support Process Development</b>, <i>Presented by Steven L., Samsung Biologics</i></p><p><b>B083: Accelerating the Discovery of a Pan-IgG Protease Using the IMPACT Platform</b>, <i>Presented by Soumya B., Seismic Therapeutic</i></p><p><b>B084: Characterization of PD-1 Agonist Moieties of a Dual Cell Bidirectional Antibody to Treat Autoimmune Diseases</b>, <i>Presented by Rasika H., Seismic Therapeutic</i></p><p><b>B085: Development of CAR-NK Cell Targeting Cancer-Associated Fibroblasts for Pancreatic Cancer Treatment</b>, <i>Presented by Jisu H., Seoul National University</i></p><p><b>B086: Fine-Tuning of Chimeric Antigen Receptor in Live Cells by Fluorescence Resonance Energy Transfer (FRET)-Based Biosensor</b>, <i>Presented by Hae Nim L., Seoul National University</i></p><p><b>B087: IL-21 On/Off Switch Loaded CAR-T Enhance Antitumor Effects by Epigenetic and Transcriptional Regulation</b>, <i>Presented by Hyungseok S., Seoul National University</i></p><p><b>B088: PSB123, an Anti-TIGIT –IL2 Fusion Protein Synergistically Activates Anti-Tumor Immune Responses Without Significant Toxicity</b>, <i>Presented by Wei Y., Sound Biologics</i></p><p><b>B089: Molecular Guidance Systems (MGSs) as Versatile Vehicles for Targeted Delivery of Oligonucleotides to Non-Hepatic Tissues</b>, <i>Presented by Michael M., SRI International</i></p><p><b>B090: TA Instruments RS-DSC: A Breakthrough in Thermal Stability Analysis</b>, <i>Presented by Christine N., TA Instruments</i></p><p><b>B091: Thermostable Raman Interaction Profiling (TRIP)</b>, <i>Presented by Narangerel A., Texas A&M University</i></p><p><b>B092: Molecular Recognition in the Interleukin-1 System</b>, <i>Presented by Glorise TM., Texas A&M University</i></p><p><b>B093:</b><b> Invitrogen™ Vivofectamine™ LNP Solutions for RNA Delivery from Mouse to NHP</b>, <i>Presented by Henry C., Thermo Fisher Scientific</i></p><p><b>B094: Optimizing Transient Protein Expression with Custom Media</b>, <i>Presented by Jason E., Thermo Fisher Scientific</i></p><p><b>B095: A Novel 5L Shake Flask Suitable for Transient Protein Expression in the ExpiCHO, Expi293 and ExpiSF Production Systems</b>, <i>Presented by Sam W., Thermo Fisher Scientific</i></p><p><b>B096: Antibody Discovery Identifies Regulatory Mechanisms of Protein Arginine Deiminase 4</b>, <i>Presented by Sophie K., University of California, San Francisco</i></p><p><b>B097: An Approach to Understand Nanobody Stability Enabling Large Scale Discovery</b>, <i>Presented by Yue W., University of California, San Francisco</i></p><p><b>B098: Solid Tumor Targeting by Cytotoxic T-Cells with a-T-Cell Receptor Nanobody Chemically Self-Assembled Nanorings (CSANs)</b>, <i>Presented by Debasmita P., University of Minnesota</i></p><p><b>B099: Structure-Based Design of a Soluble Human Cytomegalovirus Glycoprotein B Antigen Stabilized in a Prefusion-Like Conformation</b>, <i>Presented by Madeline S., University of Texas at Austin</i></p><p><b>B100: NanoLogix: An Open-Source Pipeline to Turbocharge Nanobody Discovery with High-Throughput Sequencing</b>, <i>Presented by Kathleen Z., Walter and Eliza Hall Institute of Medical Research</i></p><p><b>B101: Rapid Antibody Lead Identification from Various Species Through Single B Cell Screening (VAST-B)</b>, <i>Presented by Siwei N., WuXi Biologics</i></p><p><b>B102: Complementary Light Scattering Solutions for Protein Characterization</b>, <i>Presented by Michelle C., Wyatt Technology</i></p><p><b>B103: Strategies to Sustain Bioprocess Development and Manufacturing</b>, <i>Presented by Hassan S.,</i><i> Lucensia Biosciences LLC</i></p><p><b>B104: High Throughput Epitope Mapping and Screening in Live Cells</b>, <i>Presented by Dan B., Immuto Scientific</i></p><p> </p><p><b></b><b> </b></p><p><b><u>POSTER SESSION C: Thursday</u></b><b> </b></p><p><b>C001: ML-Guided Antibody Discovery and Optimization Using AlphaSeq and AlphaBind</b>, <i>Presented by Miranda L., A-Alpha Bio</i></p><p><b>C002: ABBV-400, a c-Met ADC: In Vitro Immunosafety Data Analysis</b>, <i>Presented by Susanne S., AbbVie</i></p><p><b>C003: IgDesign: Antibody Inverse Folding with In Vitro Validation</b>, <i>Presented by Amir S., Absci Corporation</i></p><p><b>C004: Comparing Potential Bispecific Formats of Trastuzumab and a Humanized OKT3</b>, <i>Presented by Catherine B., Absolute Antibody</i></p><p><b>C005: SARS-CoV-2 Neutralizing Antibodies Discovered in Serum Across Three Individuals Following Vaccination and Infection Show Diverse Epitopes Across Virus Spike Protein</b>, <i>Presented by Natalie C., Abterra Biosciences</i></p><p><b>C006: Development of High Throughput Screening Tools for the Purification of Bispecifics</b>, <i>Presented by Robert H., Abzena</i></p><p><b>C007: Analysis of NIST mAb Reference Material by Parallel SDS-Capillary Electrophoresis</b>, <i>Presented by Kyle L., Agilent Technologies, Inc.</i></p><p><b>C008: XtalFold: An Antibody-Antigen/Protein-Protein Complex Structure Prediction Algorithm with Unprecedented Accuracy to Accelerate Therapeutics Development</b>, <i>Presented by Kyle K., Ailux Biologics by XtalPi</i></p><p><b>C009: AJICAP® Technology Expanding Therapeutic Windows of ADCs and Accelerating Development of Novel Antibody-Based Conjugates</b>, <i>Presented by Takumi H., Ajinomoto Co., Inc.</i></p><p><b>C010: Alternative CHO Harvest Process Development Using Acid Precipitation to Enable Process Scale-Up</b>, <i>Presented by Poorvaja G., Alexion AstraZeneca Rare Diseases</i></p><p><b>C011: Real-Time Kinetic Data in the Successful Development of an Inhibition of Proliferation Potency Bioassay</b>, <i>Presented by Lauren G., Antibody Analytics</i></p><p><b>C012: Degradation Comparisons of Monoclonal Antibodies and Their Conjugated Forms</b>, <i>Presented by Dominique WD., AstraZeneca</i></p><p><b>C013: Automating the CE-SDS, CE-N Glycan and cIEF Workflows for Downstream Analysis on the BioPhase 8800 System</b>, <i>Presented by John F., Beckman Coulter Life Sciences</i></p><p><b>C014: Simple and High-Throughput Analytics for Proteins and Cells in Bioprocessing</b>, <i>Presented by Chip S., Beckman Coulter Life Sciences</i></p><p><b>C015: Identification of a Novel Trop2-Targeting Immune Stimulating Antibody Conjugate (ISAC) with Efficacy in a Model of Pancreatic Cancer</b>, <i>Presented by Mohan M., Binghamton University: The State University of New York</i></p><p><b>C016: Optimization and Evaluation of Legumain-Cleavable Topoisomerase-1 Inhibitor ADCs in a Pancreatic Cancer Model</b>, <i>Presented by Victor O., Binghamton University: The State University of New York</i></p><p><b>C017: Generation of a Fully Human Antibody Library and Novel Linker/Payload to Facilitate Development of Antibody-Drug Conjugates and Other Antibody-Based Therapeutics</b>, <i>Presented by Luis H., Biocytogen Pharmaceuticals</i></p><p><b>C018: Uncovering Factors Influencing Mannose Receptor Dependent Binding to Monoclonal Antibodies</b>, <i>Presented by Julia B., Boehringer Ingelheim Pharma GmbH & Co. KG</i></p><p><b>C019: High-Throughput Automated Microfluidic Method to Identify Mispairing During Bispecific Antibody Production</b>, <i>Presented by Jenna R., Brown University</i></p><p><b>C020: Apolipoprotein E: Purification, Characterization, and Lipid Nanoparticle Uptake Enhancement</b>, <i>Presented by Alfredo G., Cayman Chemical Company</i></p><p><b>C021: Tumbler: A Highly Customizable Antibody Optimization Suite</b>, <i>Presented by Michali I., Charles River Laboratories</i></p><p><b>C022: Structure-Based Charge Calculations for Predicting Properties and Profiling Antibody Therapeutics</b>, <i>Presented by Alain A., Chemical Computing Group</i></p><p><b>C023: A Novel uPAR-Directed Antibody-Drug-Conjugate Eliciting Tumor Regression and Immunomodulation in Preclinical Models of Pancreatic Cancer</b>, <i>Presented by Virginia M., Copenhagen University Hospital</i></p><p><b>C024: A Decoy ACE2 Shows Significant Efficacy Against SARS-CoV-2 Omicron Variants and Related Viruses: A Computational-Experimental Approach</b>, <i>Presented by Shahidul I., Delaware State University</i></p><p><b>C025: Development of a PhyTip-Based On-Resin Conjugation Workflow for OTV Biotherapeutics</b>, <i>Presented by Joanne C., Denali Therapeutics</i></p><p><b>C026: Fusion Protein Targeting PD-L1 and Neutralizing Gas6: A Potential Game Changer to Overcome the Glass Ceiling of Efficacy in Cancer Immunotherapy</b>, <i>Presented by Hui Chieh Y., Development Center for Biotechnology</i></p><p><b>C027: Discovery and Characterization of Biased Agonist and Antagonist Anti-hCCR5 Antibodies Using 3rd Generation ebBRET Biosensors</b>, <i>Presented by Guilhem D., Domain Therapeutics</i></p><p><b>C028: An Analysis of the Human Immunoglobulin Paired Repertoire Using Single Cell 10X and Overlap Extension RT-PCR Techniques</b>, <i>Presented by Monica W., Dotmatics, Inc.</i></p><p><b>C029: Automated Spectrum Annotation and Structure Disambiguation of Released N-Linked Glycans</b>, <i>Presented by Gary W., Dotmatics, Inc.</i></p><p><b>C030: Drug-to-Antibody Ratio of Maleimide-Based ADCs Greatly Impacts Fc Receptor Binding and Fc-Mediated Effector Activity</b>, <i>Presented by Danielle F., Eisai, Inc.</i></p><p><b>C031: Engineering EVOLVE-106: A B7-H4-Targeting T Cell Engager with Integrated CD2 Co-Stimulation</b>, <i>Presented by Sonali D., EvolveImmune Therapeutics</i></p><p><b>C032: Automated Peptide Mapping and Intact Mass Analysis Data Processing Workflows for Streamlined MS-Based Characterization of AAV Capsids</b>, <i>Presented by Catherine E., Genedata AG</i></p><p><b>C033: Accelerating Biopharmaceutical and Vaccine Research, Discovery, and Development with Genedata</b>, <i>Presented by Jana H., Genedata AG</i></p><p><b>C034: High-Throughput Generation, Design, Production, and Evaluation of Bispecific Antibodies</b>, <i>Presented by Christian T., Genedata AG</i></p><p><b>C035: A Cell Penetrating Cystine-Knot Peptide for Cargo Delivery</b>, <i>Presented by Yanjie L., Genentech</i></p><p><b>C036: FORGE™-ML: A Diffusion Model-Based Framework for Designing Multi-Functional Proteins</b>, <i>Presented by Margaret L., Gensaic</i></p><p><b>C037: Functional Enzyme Discovery and Machine Learning Guided Enzyme Optimization for Biocatalysts</b>, <i>Presented by Joseph F. and Shurong H., Ginkgo Bioworks</i></p><p><b>C038: Comparative Analysis of N-1 Perfusion Strategies for Enhanced Protein Expression and Cost Efficiency in Biopharmaceutical Manufacturing</b>, <i>Presented by Sarah L., Hangzhou HealSun Biopharm Co., Ltd.</i></p><p><b>C039: High Endothelial Venule-Targeting Drug Delivery in Metastatic Cancers</b>, <i>Presented by Sungwook J., Harvard Medical School</i></p><div><b>C040: Evaluation of a Bispecific Antibody Platform Using a 15 x 15 Matrix of Clinical Stage Antibodies</b>, <i>Presented by Jonathan D., Creative Antibodies</i></div><div><br /></div><p><b style="background-color:transparent;color:inherit;font-size:inherit;text-align:inherit;text-transform:inherit;word-spacing:normal;caret-color:auto;white-space:inherit;">C041: From Screening to Large Scale Purification: Adaptability of MagStrep® Strep-Tactin®XT Beads</b><font color="inherit" face="inherit" size="-1">, </font><i style="background-color:transparent;color:inherit;font-family:inherit;font-size:inherit;text-align:inherit;text-transform:inherit;word-spacing:normal;caret-color:auto;white-space:inherit;">Presented by Fabian M., IBA Lifesciences</i><br /></p><p><b>C042: The Cell Division Activator Protein of Salmonella typhi (StCAP) is a Key Pathogenic Inducer and Can Be Targeted with Selective Therapeutic Molecules</b>, <i>Presented by Bishwajit K., Indian Institute of Technology, Delhi</i></p><p><b>C043: Engineering an Improved Inhibitor of 53BP1 to Enhance HDR Efficiency</b>, <i>Presented by Christopher V., Integrated DNA Technologies, Inc.</i></p><p><b>C044: Small and Mighty – VHH ‘Bolt-Ons’ to Expand Therapeutic Functionality</b>, <i>Presented by Anna B., Isogenica Ltd.</i></p><p><b>C045: Tailored AAV Solutions: ELISA Kits and Customized Variant Kit Development</b>, <i>Presented by </i><i>Tingxu C.</i><i>, Kactus</i></p><p><b>C046: Accelerated Lead Cell Line Selection Through Early Process and CQA Screening with Cutting-Edge Technologies</b>, <i>Presented by Amelie M., KBI Biopharma</i></p><p><b>C047: A Novel Vector System for One-Step Generation of Diverse Vector Assemblies for Enhanced Product Titres of Multispecific Antibodies</b>, <i>Presented by Michael A., Lonza</i></p><p><b>C048: TheraPRO® CHO Media System: Achieve High Productivity in CHOK1 GS-KO® Cell Lines with Our Advanced Formulated, Easy-to-Use Media and Feed Solution</b>, <i>Presented by Gaurav K., Lonza</i></p><p><b>C049: Engineering Multi-Specific Antibodies for Prophylactic Treatment of Peanut Allergy</b>, <i>Presented by Rahel S., Mabylon AG</i></p><p><b>C050: Tuning Heterodimeric Cytokine Receptor Signaling with Bispecific Antibody Agonists</b>, <i>Presented by Shaheen F., Merck & Co., Inc.</i></p><p><b>C051: Analytical High-Throughput Automation: Advancing Vaccine Process Development</b>, <i>Presented by Carl H., Merck & Co., Inc.</i></p><p><b>C052: Evaluation of a Growth-Based Rapid Microbiological Method for Detection of Aerobic and Anaerobic Bacteria in Recombinant Pharmaceuticals</b>, <i>Presented by Hokyung O., Ministry of Food and Drug Safety, Korea</i></p><p><b>C053: Controls of Drug-to-Antibody Ratio for Site-Specific and Non-Site-Specific Antibody-Drug-Conjugates</b>, <i>Presented by Lin-Lu T., Mycenax Biotech, Inc..</i></p><p><b>C054: Accelerating the Development of Innovative Biologics in Canada</b>, <i>Presented by Melanie A., National Research Council Canada</i></p><p><b>C055: Noncanonical Intradomain Disulfide Linkages in Immunoglobulin Variable Domains: Implications in Efficacy Engineering of Antibody Therapeutics</b>, <i>Presented by Jamshid T., National Research Council Canada</i></p><p><b>C056: Directed and Efficient Therapeutic Cytokine Engineering Powered by AI and High Throughput Experimentation</b>, <i>Presented by Yang X., neoX Biotech, Inc.</i></p><p><b>C057: Identifying the Determinants of Cell-Penetrant Miniproteins</b>, <i>Presented by Claire P., Northwestern University</i></p><p><b>C058: Enhancing Solubility of Protein Targets: Innovations in Expression Strategies Using eProtein Discovery™</b>, <i>Presented by Chava A., Nuclera</i></p><p><b>C059: DNA to Assay-Ready Proteins in 48 Hours: Rapid Protein Expression and Purification on the eProtein Discovery™ System and Binding Confirmation on Biacore™ SPR System</b>, <i>Presented by Yvonne T., Nuclera</i></p><p><b>C060: OmniChicken Derived Antibodies to a Member of the TNF Receptor Superfamily</b>, <i>Presented by Darlene P., OmniAb, Inc.</i></p><p><b>C061: Cloud Enabled NGS-Based Antibody Discovery and 3D Antibody Structural Modeling</b>, <i>Presented by Suhani N., OpenEye Cadence Molecular Sciences</i></p><p><b>C062: Performing Protein Expression, Purification, and Quantification on a Robotic Liquid Handling Platform</b>, <i>Presented by Boren L., Opentrons Labworks</i></p><p><b>C063: High Throughput Hydrophobicity and Polyreactivity Assays for 6His-Tagged Proteins</b>, <i>Presented by Aris P., PAIA Biotech GmbH</i></p><p><b>C064: Investigating the Excipient Effect In Vitro for Subcutaneous Pre-Clinical Formulations</b>, <i>Presented by Imogen A., Pion, Inc.</i></p><p><b>C065: OpenCRISPR: Language Models Generate Novel Genome Editors from Scratch</b>, <i>Presented by Jeffrey R., Profluent Bio</i></p><p><b>C066: A Powerful Capillary Electrophoresis Platform for the Characterization of Viral Capsid Proteins of Vectors Used in Cell and Gene Therapies</b>, <i>Presented by Yasef K., ProteinSimple, a Bio-Techne brand</i></p><p><b>C067: Overcoming Obstacles in Antibody Discovery: Investigating the Power of De Novo Polyclonal Sequencing</b>, <i>Presented by Jennifer C., Rapid Novor</i></p><p><b>C068: Affinity Enrichment to Support Evaluation of Impactful Post-Translational Modifications on Therapeutic Monoclonal Antibodies</b>, <i>Presented by Jethro P., Regeneron Pharmaceuticals</i></p><p><b>C069: Longitudinal Deep Multi-Omics Profiling in a CLN3Δex7/8 Minipig Model Reveals Novel Biomarker Signatures for Batten Disease</b>, <i>Presented by Hannah L., Sanford Research</i></p><p><b>C070: Machine Learning Guided Identification of Novel Antibody Sequences with Defined Specificity</b>, <i>Presented by Ankit M., Sanofi</i></p><p><b>C071: Analytical Challenges for Developability Assessment of Multispecific Antibodies</b>, <i>Presented by Megan S., Sanofi</i></p><p><b>C072: Diagnostic Potential of BCR Repertoire NGS Analysis and Stereotypic BCR Clonotype Proved in Mouse B Cell Lymphoma Model</b>, <i>Presented by Soyeon J., Seoul National University</i></p><p><b>C073: Fully Human DLL3/CD3 TCEs with Excellent Killing Potency Against Small Cell Lung Cancer (SCLC) Cells</b>, <i>Presented by Jinghua G., Shanghai AceMab Biotechnology Ltd.</i></p><p><b>C074: SPOC Biosensor Chips as a Novel Tool for Evaluating AI-Designed Antibody-Based Therapeutics’ Specificity Against Thousands of Targets Simultaneously</b>, <i>Presented by Bharath T., SPOC Proteomics</i></p><p><b>C075:</b><b> STRO-004: A Precisely Designed Tissue Factor Targeted ADC for Broadened Efficacy and Safety</b>, <i>Presented by Grace L., Sutro Biopharma</i></p><p><b>C076: Machine Learning-Based Engineering of Reagent Enzymes Improves Nucleic Acid Detection: Application to Infectious Disease and Cancer Diagnostics</b>, <i>Presented by Thomas S., Tamarack Bioscience, Inc.</i></p><p><b>C077: Targeted In Silico Design of Functional Enzyme Inhibitors</b>, <i>Presented by Darian W., Technical University of Denmark</i></p><p><b>C078: AI-Driven Screening of Blocking Antibodies Using tFold Structural Modeling</b>, <i>Presented by Biaobin J., Tencent</i></p><p><b>C079: Leveraging Cryo-Electron Microscopy for Innovative Vaccine Development</b>, <i>Presented by Tilak G., Thermo Fisher Scientific</i></p><p><b>C080: Accelerating Discovery and Rational Engineering of Antibody Modalities Using Cryo-EM</b>, <i>Presented by Anass J., Thermo Fisher Scientific</i></p><p><b>C081: Improving Intracellular Delivery of an Antibody-Drug Conjugate Targeting Carcinoembryonic Antigen Increases Efficacy at Clinically Relevant Doses In-Vivo</b>, <i>Presented by Baron R., University of Michigan</i></p><p><b>C082: Building the Protein-Drug Revolution</b>, <i>Presented by Sneha V., University of Minnesota</i></p><p><b>C083: High Throughput Cysteinylation Screening at mAb Subunit Level Using LC-MS Monitoring Workflow</b>, <i>Presented by Guillaume B., Waters Corporation</i></p><p><b>C084: Simple and Automatable Sample Preparation for Tryptic Peptide Mapping with the PeptideWorks Kit</b>, <i>Presented by Erin M., Waters Corporation</i></p><p><b>C085: WuXi XDC’s Development Platforms Deliver Consistent and Scalable Conjugation Processes</b>, <i>Presented by Stuart W., WuXi Biologics</i></p><p><b>C086: From Sequence to Binding Clones, a Novel Computational Platform for Nanobody Discovery</b>, <i>Presented by Hao C., Yurogen Biosystems LLC</i></p><p><b>C087: Development of Rabbit Anti-Mertansine (DM1) Monoclonal Antibodies</b>, <i>Presented by Ke Z, Yurogen Biosystems LLC</i></p><p><b>C088: Development of CD40 and HER2 Bispecific Antibodies for Enhanced Efficacy Against HER2-Positive Tumors</b>, <i>Presented by Yang L., Yurogen Biosystems LLC</i></p><p><b>C089: Cell-Free Expression of Antibodies from Veterinary Species</b>, <i>Presented by Erika O., Zoetis</i></p><p><b>C090: Characterization of Livestock IgG Repertoire</b>, <i>Presented by Prajna S., Zoetis</i></p><p><b>C091: TriTCE Co-Stim: A Next Generation Trispecific T Cell Engager Platform with Integrated CD28 Costimulation, Engineered to Improve T Cell Function and Antitumor Responses in Hard-to-Treat Cancers</b>, <i>Presented by </i><i>Prajwal R. and Gursev A.</i><i>, Zymeworks, Inc.</i></p><p><b>C092: Harnessing Display Technologies to Obtain Large Datasets for Machine Learning Training and Enhance Diagnostic Tools</b>, <i>Presented by Esen S., Los Alamos National Laboratory</i></p><p><b>C093: Genovac OptiAb™ Powered by ENPICOM- A Deep Learning Tool and Service for Next Generation Antibody Humanization</b>, <i>Presented by Matt W., Genovac Antibody Discovery</i></p><div><p><b>C094: Supporting CAR-T Cell Therapy Development from Discovery to IND-Filing</b>, <i>Presented by Brad G., Charles River Laboratories</i></p></div><div><p><b>C095: Bispecific Antibody Discovery Platform for IND Enabling Studies</b>, <i>Presented by Brad G., Charles River Laboratories</i></p><p><b>C096: Cancerlysins™: Novel Bispecific Antibodies for Non-Toxic Targeted Tumor Eradication</b>, <i>Presented by Victor G., ImmuVia LLC</i></p></div><p> </p><p> 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