Biomarkers in Psychiatry for Mental Health and Wellbeing

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id="main-content"> <div class="resource-single"> <div class="header bg-primary-light"> <div class="container-wrapper"> <div class="wide-container header-container"> <div class="header-content flex-1"> <div class="heading-smallcaps"> Clinical Development | Industry Spotlights & Insight Articles </div> <h1 class="heading"> Biomarkers in Psychiatry for Mental Health and Wellbeing </h1> <div class="byline"> Edited by Ben Norris | 19 May 2023 </div> <div class="abstract"> Biomarkers in psychiatry may have the potential to overcome the challenges associated with complications such as depression, bipolar disorder, and generalised anxiety. </div> </div> <div class="header-graphic flex-1"> <img src="https://oxfordglobal.com/hubfs/Website/Images/Resources/Biomarkers/Biomarkers-in-Psychiatry-for-Mental-Health-and-Wellbeing.jpg" class="header-graphic-image"> </div> </div> </div> </div> <div class="container-wrapper"> <div class="wide-container"> <div class="content"> <div class="content-body text-gap">  <p>Clinical and prognostic biomarkers in psychiatry may be used to identify patients more likely to develop a clinical event or disease progression. </p>   <p>In recent years, a concerted effort has been made to identify mental health biomarkers as potential tools for improving responses to psychiatric disorders. </p>   <p>Mental issues are categorised by diagnostic categories with a broad list of symptoms and prognostic causes. </p>   <p>As such, there is significant variety in how these mental illnesses can arise and present themselves in patients. </p>   <ul> <li><a href="https://oxfordglobal.com/biomarkers/resources/improving-approaches-for-patient-selection-using-immuno-oncology-biomarkers/" target="_blank" rel="noreferrer noopener">Improving patient selection using immune checkpoint inhibitors</a></li>   <li><a href="https://oxfordglobal.com/biomarkers/resources/multimodal-biomarkers-how-screening-approaches-can-benefit-from-ai/" target="_blank" rel="noreferrer noopener">How can screening approaches benefit from AI?</a></li>   <li><a href="https://oxfordglobal.com/biomarkers/resources/ai-in-digital-pathology-the-applications-of-explainable-ai-and-deep-learning-approaches-in-clinical-practice/" target="_blank" rel="noreferrer noopener">Using deep learning in clinical practice</a></li> </ul>   <p></p>   <p>This fact, together with patchy knowledge around the neurochemical alterations that can underlie mental health issues, contributes to the limited efficacy of pharmacological options. </p>   <p>The identification of relevant biomarkers in psychiatry could one day be essential to assisting diagnosis through the development of markers that allow for the stratification of groups within the syndrome. </p>   <p>By identifying factors predicting treatment response, researchers could be able to facilitate the discovery of new, effective treatments, reducing trial-and-error switches of medications.</p>   <p>This would represent a crucial step towards the establishment of greater personalised medicine for mental health issues. </p>   <h2 id="h-applications-of-clinical-and-prognostic-biomarkers-in-psychiatry"><strong>Applications of Clinical and Prognostic Biomarkers in Psychiatry</strong></h2>   <p>Advances in psychiatry and research centred on the human brain – along with the advent of new technologies such as ‘omics’ technologies – offer the opportunity for augmented mental health treatment. </p>   <p>As an example, the precise identification of distinct biomarkers for psychiatric disorders could enable a psychiatrist to tailor therapies towards individuals affected by them. </p>   <p>Imaging biomarkers can also determine which pharmacological treatments for major depressive disorder (MDD) are effective or ineffective for specific individuals who have already been diagnosed. </p>   <p>These approaches could be used to measure and monitor responses to cognitive behavioural therapy (CBT), electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), or deep brain stimulation (DBS). </p>   <p>Here, the aim would be to ameliorate the problem of treatment resistance in depression: patients who fail to respond to antidepressant medication may respond to different forms of neuromodulation. </p>   <p>Biomarkers specific to each patient’s brain could determine which of these interventions would be more likely to modulate neural and mental function, providing a tailored approach to treatment with a higher likelihood of a successful outcome.</p>   <p>Further down the line, the potential is there for this approach to guide interventions and control other disorders. </p>   <p>There is uncertainty about the role of these biological signatures in neural pathophysiology, and their clinical significance has yet to be firmly established. </p>   <p>Still, the potential is there for biomarkers in biological psychiatry to overcome the challenges associated with depression, bipolar disorder, and generalised anxiety.</p>   <p><em>Get your weekly dose of industry news and announcements </em><a href="https://oxfordglobal.com/biomarkers/news/" target="_blank" rel="noreferrer noopener"><em>here</em></a><em>, or head over to our </em><a href="https://oxfordglobal.com/biomarkers/" target="_blank" rel="noreferrer noopener"><em>Biomarkers</em></a><em> portal to catch up with the latest advances in cellular therapies.</em></p>  <div class="content-body-footer"> </div> </div> <div class="content-sidebar"> <div class="related-articles"> <h3 class="center">Related Resources</h3> <div class="article"> <a href="/precision-medicine/resources/immunoassay-solutions-for-biomarker-analysis"> <div class="cover-graphic"> <img src="https://oxfordglobal.com/hubfs/Website/Documents/Whitepaper%20Upload%2022.10.24/AB0285_Immunoassay_Solutions_Ab_Pairs_UPDATE_DIGITAL%20(1).jpg" class="cover-graphic-image"> </div> </a><div class="content"><a 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Biomarkers in Psychiatry for Mental Health and Wellbeing