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Focuses on how researchers discover the genetics of diseases and how those discoveries are used to improve clinical practice. Surveys aspects of (i) the molecular function of the human genome, (ii) the basic principles of human genetics including statistical genetics, quantitative genetics, and genomic variation in human populations, (iii) the genetics of rare disorders and common diseases, and genomic analysis approaches, including genome-wide association studies and sequencing, and (iv) how genetics are used in medicine and discussions covering ethical considerations of human genomic data.<br/> </p> <button class="notinpdf cb-extras-toggle" aria-expanded="false" onclick="toggleCourseBlockInfo(this); return false;"><svg aria-hidden="true"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-caret-down"></use></svg>View details</button><div class="cb-extras" aria-hidden="true"><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Requisites: </strong></span></strong></span><span class="cbextra-data"><a href="/search/?P=GENETICS%20466" title="GENETICS 466" class="bubblelink code" onclick="return showCourse(this, 'GENETICS 466');">GENETICS 466</a>, <a href="/search/?P=GENETICS%20468" title="GENETICS 468" class="bubblelink code" onclick="return showCourse(this, 'GENETICS 468');">468</a>, <a href="/search/?P=BIOCORE%20587" title="BIOCORE 587" class="bubblelink code" onclick="return showCourse(this, 'BIOCORE 587');">BIOCORE 587</a>, or graduate/professional standing</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Course Designation: </strong></span></strong></span><span class="cbextra-data">Breadth - Biological Sci. Counts toward the Natural Sci req<br/> Level - Intermediate<br/> L&S Credit - Counts as Liberal Arts and Science credit in L&S<br/> Grad 50% - Counts toward 50% graduate coursework requirement</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Repeatable for Credit: </strong></span></strong></span><span class="cbextra-data">No</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Last Taught: </strong></span></strong></span><span class="cbextra-data">Fall 2024</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong></strong></span><span class="cbextra-data"><div class="bubblehide"><p class="courseblockextra noindent clearfix"><span class="cbextra-label"><strong>Learning Outcomes: </strong></span><span class="cbextra-data">1. Predict and describe how different classes of genetic variants, as defined by (a) mutation mechanism, (b) variant size, (c) population frequency, and (d) location in the genome, could affect molecular and cellular functions and risk for disease<br/>Audience: Both Grad & Undergrad<br/><br/>2. Design experimental approaches to investigate the mechanisms of human genetic disorders<br/>Audience: Both Grad & Undergrad<br/><br/>3. Explain and give examples of genetic inheritance patterns and the contribution of inherited factors to disease risk<br/>Audience: Both Grad & Undergrad<br/><br/>4. Describe the design, strengths, and weaknesses of the various approaches for identifying genes or loci associated with a human disease or trait (e.g. linkage mapping, genetic association, sequencing), and interpret results from these studies<br/>Audience: Both Grad & Undergrad<br/><br/>5. Explain how genetic information is used in the practice of medicine for diagnosis or to guide treatment and the limitations of current clinical diagnostic or treatment tools<br/>Audience: Both Grad & Undergrad<br/><br/>6. Apply human genetics concepts to critically analyze published scientific studies and to describe experimental approaches that can be performed to address shortcomings and/or extend the findings of published work<br/>Audience: Graduate</span></p></div></span></p></div></div><style>.lfjsbubblemain .bubblehide {display: none !important;}.searchresult .bubblehide {display: none !important;}</style><div class="courseblock "> <p class="courseblocktitle noindent"><strong><span class="courseblockcode">MD GENET/BIOCHEM/GENETICS 620</span> — EUKARYOTIC MOLECULAR BIOLOGY</strong></p> <p class="courseblockcredits">3 credits.</p> <p class="courseblockdesc noindent"> Focuses on the basic molecular mechanisms that regulate DNA, RNA, and protein metabolism in eukaryotic organisms.<br/> </p> <button class="notinpdf cb-extras-toggle" aria-expanded="false" onclick="toggleCourseBlockInfo(this); return false;"><svg aria-hidden="true"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-caret-down"></use></svg>View details</button><div class="cb-extras" aria-hidden="true"><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Requisites: </strong></span></strong></span><span class="cbextra-data"><a href="/search/?P=BIOCHEM%20501" title="BIOCHEM 501" class="bubblelink code" onclick="return showCourse(this, 'BIOCHEM 501');">BIOCHEM 501</a>, <a href="/search/?P=BIOCHEM%20508" title="BIOCHEM 508" class="bubblelink code" onclick="return showCourse(this, 'BIOCHEM 508');">508</a> or graduate/professional standing</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Course Designation: </strong></span></strong></span><span class="cbextra-data">Level - Intermediate<br/> L&S Credit - Counts as Liberal Arts and Science credit in L&S<br/> Grad 50% - Counts toward 50% graduate coursework requirement</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Repeatable for Credit: </strong></span></strong></span><span class="cbextra-data">No</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Last Taught: </strong></span></strong></span><span class="cbextra-data">Spring 2024</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong></strong></span><span class="cbextra-data"><div class="bubblehide"><p class="courseblockextra noindent clearfix"><span class="cbextra-label"><strong>Learning Outcomes: </strong></span><span class="cbextra-data">1. Recall core principles that govern the structure and function of DNA, RNA, and protein.<br/>Audience: Both Grad & Undergrad<br/><br/>2. Describe techniques for quantifying the expression, interaction, and cellular localization of specific molecules and for determining their necessity and sufficiency in molecular processes.<br/>Audience: Both Grad & Undergrad<br/><br/>3. Explain how molecular processes that control the synthesis, decay, interactions, localization, folding, and modification of molecules are silenced, initiated, maintained, and terminated.<br/>Audience: Both Grad & Undergrad<br/><br/>4. Describe how information is transferred between molecules to alter cellular activity in response to developmental and environmental signals.<br/>Audience: Both Grad & Undergrad<br/><br/>5. Critique and weigh the credibility of existing molecular data.<br/>Audience: Both Grad & Undergrad<br/><br/>6. Develop and draw hypotheses that use existing data to account for as yet unexplained molecular processes in eukaryotic organisms.<br/>Audience: Both Grad & Undergrad<br/><br/>7. Design discovery/observation, loss-of-function, and gain-of-function experiments to test molecular hypotheses.<br/>Audience: Both Grad & Undergrad<br/><br/>8. Implement problem solving strategies in thesis research project.<br/>Audience: Graduate</span></p></div></span></p></div></div><style>.lfjsbubblemain .bubblehide {display: none !important;}.searchresult .bubblehide {display: none !important;}</style><div class="courseblock "> <p class="courseblocktitle noindent"><strong><span class="courseblockcode">MD GENET/GENETICS/POP HLTH 636</span> — PUBLIC HEALTH GENOMICS</strong></p> <p class="courseblockcredits">1 credit.</p> <p class="courseblockdesc noindent"> Provides an introduction to public health genomics through a review of fundamental principles of genetics, the use of genetic information in clinical and research settings, and its implications for disease management and prevention, and health promotion. Explores policies that guide public health and discusses current ethical, legal, and social implications of these policies.<br/> </p> <button class="notinpdf cb-extras-toggle" aria-expanded="false" onclick="toggleCourseBlockInfo(this); return false;"><svg aria-hidden="true"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-caret-down"></use></svg>View details</button><div class="cb-extras" aria-hidden="true"><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Requisites: </strong></span></strong></span><span class="cbextra-data">(Junior standing and <a href="/search/?P=ZOOLOGY%20151" title="ZOOLOGY/BIOLOGY/BOTANY 151" class="bubblelink code" onclick="return showCourse(this, 'ZOOLOGY 151');">ZOOLOGY/BIOLOGY/BOTANY 151</a>) or graduate/professional standing</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Course Designation: </strong></span></strong></span><span class="cbextra-data">Grad 50% - Counts toward 50% graduate coursework requirement</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Repeatable for Credit: </strong></span></strong></span><span class="cbextra-data">No</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Last Taught: </strong></span></strong></span><span class="cbextra-data">Spring 2022</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong></strong></span><span class="cbextra-data"><div class="bubblehide"><p class="courseblockextra noindent clearfix"><span class="cbextra-label"><strong>Learning Outcomes: </strong></span><span class="cbextra-data">1. Discuss the impact of genetics on clinical care and public health practice<br/>Audience: Both Grad & Undergrad<br/><br/>2. Critically discuss genetic/genomic policies and the relevant ethical, legal, and social implications (ELSI) of these policies<br/>Audience: Both Grad & Undergrad<br/><br/>3. Read, summarize, critique, and relate current news articles to key concepts in public health genomics<br/>Audience: Graduate</span></p></div></span></p></div></div><style>.lfjsbubblemain .bubblehide {display: none !important;}.searchresult .bubblehide {display: none !important;}</style><div class="courseblock "> <p class="courseblocktitle noindent"><strong><span class="courseblockcode">MD GENET/GENETICS 662</span> — CANCER GENETICS</strong></p> <p class="courseblockcredits">3 credits.</p> <p class="courseblockdesc noindent"> Focuses on the genetic basis by which cancer manifests. Provides a comprehensive overview of how cancer is generated as a result of abnormalities at the DNA level, paying special attention to oncogenes, tumor suppressors, DNA mutations, DNA repair mechanisms, chromosomal instability, and tumor heterogeneity. Stresses the role of the immune system in combating cancer, the phenomenon of cancer resistance, anti-tumor strategies, and epigenetic influences on tumorigenesis. Highlights connections between course material and clinical relevance.<br/> </p> <button class="notinpdf cb-extras-toggle" aria-expanded="false" onclick="toggleCourseBlockInfo(this); return false;"><svg aria-hidden="true"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-caret-down"></use></svg>View details</button><div class="cb-extras" aria-hidden="true"><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Requisites: </strong></span></strong></span><span class="cbextra-data"><a href="/search/?P=GENETICS%20466" title="GENETICS 466" class="bubblelink code" onclick="return showCourse(this, 'GENETICS 466');">GENETICS 466</a>, <a href="/search/?P=GENETICS%20467" title="GENETICS 467" class="bubblelink code" onclick="return showCourse(this, 'GENETICS 467');">467</a> or <a href="/search/?P=BIOCORE%20383" title="BIOCORE 383" class="bubblelink code" onclick="return showCourse(this, 'BIOCORE 383');">BIOCORE 383</a></span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Course Designation: </strong></span></strong></span><span class="cbextra-data">Breadth - Biological Sci. Counts toward the Natural Sci req<br/> Level - Advanced<br/> L&S Credit - Counts as Liberal Arts and Science credit in L&S</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Repeatable for Credit: </strong></span></strong></span><span class="cbextra-data">No</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Last Taught: </strong></span></strong></span><span class="cbextra-data">Spring 2024</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong></strong></span><span class="cbextra-data"><div class="bubblehide"><p class="courseblockextra noindent clearfix"><span class="cbextra-label"><strong>Learning Outcomes: </strong></span><span class="cbextra-data">1. Describe major research advances in cancer genetics<br/>Audience: Undergraduate<br/><br/>2. Discuss the promises and challenges that await the field of cancer genetics.<br/>Audience: Undergraduate<br/><br/>3. Apply your understanding of cancer genetics to generate research questions and improve hypothetical patient care<br/>Audience: Undergraduate<br/><br/>4. Critically evaluate primary literature regarding cancer genetics<br/>Audience: Undergraduate<br/><br/>5. Organize and deliver a scientific presentation to your peers<br/>Audience: Undergraduate</span></p></div></span></p></div></div><style>.lfjsbubblemain .bubblehide {display: none !important;}.searchresult .bubblehide {display: none !important;}</style><div class="courseblock "> <p class="courseblocktitle noindent"><strong><span class="courseblockcode">MD GENET/GENETICS 677</span> — ADVANCED TOPICS IN GENETICS</strong></p> <p class="courseblockcredits">1-3 credits.</p> <p class="courseblockdesc noindent"> Contents vary; consideration of subjects not included in the curriculum.<br/> </p> <button class="notinpdf cb-extras-toggle" aria-expanded="false" onclick="toggleCourseBlockInfo(this); return false;"><svg aria-hidden="true"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-caret-down"></use></svg>View details</button><div class="cb-extras" aria-hidden="true"><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Requisites: </strong></span></strong></span><span class="cbextra-data">Graduate/professional standing, <a href="/search/?P=GENETICS%20466" title="GENETICS 466" class="bubblelink code" onclick="return showCourse(this, 'GENETICS 466');">GENETICS 466</a>, <a href="/search/?P=GENETICS%20468" title="GENETICS 468" class="bubblelink code" onclick="return showCourse(this, 'GENETICS 468');">468</a>, or <a href="/search/?P=BIOCORE%20383" title="BIOCORE 383" class="bubblelink code" onclick="return showCourse(this, 'BIOCORE 383');">BIOCORE 383</a></span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Course Designation: </strong></span></strong></span><span class="cbextra-data">Breadth - Biological Sci. Counts toward the Natural Sci req<br/> Level - Advanced<br/> L&S Credit - Counts as Liberal Arts and Science credit in L&S<br/> Grad 50% - Counts toward 50% graduate coursework requirement</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Repeatable for Credit: </strong></span></strong></span><span class="cbextra-data">Yes, unlimited number of completions</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Last Taught: </strong></span></strong></span><span class="cbextra-data">Fall 2024</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong></strong></span><span class="cbextra-data"><div class="bubblehide"><p class="courseblockextra noindent clearfix"><span class="cbextra-label"><strong>Learning Outcomes: </strong></span><span class="cbextra-data">1. Apply, analyze, or evaluate advanced theories, concepts, or methods in genetics and genomics. <br/>Audience: Both Grad & Undergrad<br/><br/>2. Apply knowledge of experimental genetics and genomics to related research projects.<br/>Audience: Graduate</span></p></div></span></p></div></div><style>.lfjsbubblemain .bubblehide {display: none !important;}.searchresult .bubblehide {display: none !important;}</style><div class="courseblock "> <p class="courseblocktitle noindent"><strong><span class="courseblockcode">MD GENET 699</span> — INDEPENDENT READING</strong></p> <p class="courseblockcredits">1-3 credits.</p> <p class="courseblockdesc noindent"> Directed study projects as arranged with instructor.<br/> </p> <button class="notinpdf cb-extras-toggle" aria-expanded="false" onclick="toggleCourseBlockInfo(this); return false;"><svg aria-hidden="true"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-caret-down"></use></svg>View details</button><div class="cb-extras" aria-hidden="true"><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Requisites: </strong></span></strong></span><span class="cbextra-data">Consent of instructor</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Course Designation: </strong></span></strong></span><span class="cbextra-data">Level - Advanced<br/> L&S Credit - Counts as Liberal Arts and Science credit in L&S</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Repeatable for Credit: </strong></span></strong></span><span class="cbextra-data">Yes, unlimited number of completions</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Last Taught: </strong></span></strong></span><span class="cbextra-data">Fall 2015</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong></strong></span><span class="cbextra-data"><div class="bubblehide"><p class="courseblockextra noindent clearfix"><span class="cbextra-label"><strong>Learning Outcomes: </strong></span><span class="cbextra-data">1. Apply concepts learned in coursework to real life situations<br/>Audience: Undergraduate<br/><br/>2. Develop critical, analytical, and independent thinking skills<br/>Audience: Undergraduate</span></p></div></span></p></div></div><style>.lfjsbubblemain .bubblehide {display: none !important;}.searchresult .bubblehide {display: none !important;}</style><div class="courseblock "> <p class="courseblocktitle noindent"><strong><span class="courseblockcode">MD GENET/GENETICS 707</span> — GENETICS OF DEVELOPMENT</strong></p> <p class="courseblockcredits">3 credits.</p> <p class="courseblockdesc noindent"> A research-level analysis of the current status of the investigation of processes controlling differential gene activity and cellular behavior. The major emphasis is genetic. In successive years, the focus moves from the gene to the cell to the organism.<br/> </p> <button class="notinpdf cb-extras-toggle" aria-expanded="false" onclick="toggleCourseBlockInfo(this); return false;"><svg aria-hidden="true"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-caret-down"></use></svg>View details</button><div class="cb-extras" aria-hidden="true"><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Requisites: </strong></span></strong></span><span class="cbextra-data">Declared in Genetics graduate program</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Course Designation: </strong></span></strong></span><span class="cbextra-data">Grad 50% - Counts toward 50% graduate coursework requirement</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Repeatable for Credit: </strong></span></strong></span><span class="cbextra-data">Yes, unlimited number of completions</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Last Taught: </strong></span></strong></span><span class="cbextra-data">Spring 2023</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong></strong></span><span class="cbextra-data"><div class="bubblehide"><p class="courseblockextra noindent clearfix"><span class="cbextra-label"><strong>Learning Outcomes: </strong></span><span class="cbextra-data">1. Critically evaluate papers, form meaningful questions based on the material, and engage scientists in conversations about their work.<br/>Audience: Graduate<br/><br/>2. Improve oral presentations and scientific writing (grants, review articles).<br/>Audience: Graduate<br/><br/>3. Expand scientific literacy.<br/>Audience: Graduate</span></p></div></span></p></div></div><style>.lfjsbubblemain .bubblehide {display: none !important;}.searchresult .bubblehide {display: none !important;}</style><div class="courseblock "> <p class="courseblocktitle noindent"><strong><span class="courseblockcode">MD GENET/GENETICS 708</span> — METHODS AND LOGIC IN GENETIC ANALYSIS</strong></p> <p class="courseblockcredits">3 credits.</p> <p class="courseblockdesc noindent"> Contemporary issues in genetic, developmental, cell, and molecular biology are addressed in a discussion format. Invited speakers give research lectures and reading material is taken from the primary literature. The discussion focuses on evaluating genetic approaches to biological problems.<br/> </p> <button class="notinpdf cb-extras-toggle" aria-expanded="false" onclick="toggleCourseBlockInfo(this); return false;"><svg aria-hidden="true"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-caret-down"></use></svg>View details</button><div class="cb-extras" aria-hidden="true"><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Requisites: </strong></span></strong></span><span class="cbextra-data">Declared in Genetics graduate program</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Course Designation: </strong></span></strong></span><span class="cbextra-data">Grad 50% - Counts toward 50% graduate coursework requirement</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Repeatable for Credit: </strong></span></strong></span><span class="cbextra-data">No</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Last Taught: </strong></span></strong></span><span class="cbextra-data">Spring 2024</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong></strong></span><span class="cbextra-data"><div class="bubblehide"><p class="courseblockextra noindent clearfix"><span class="cbextra-label"><strong>Learning Outcomes: </strong></span><span class="cbextra-data">1. Critically evaluate papers, form meaningful questions based on the material, and engage scientists in conversations about their work.<br/>Audience: Graduate<br/><br/>2. Improve oral presentations and scientific writing (grants, review articles).<br/>Audience: Graduate<br/><br/>3. Expand scientific literacy.<br/>Audience: Graduate</span></p></div></span></p></div></div><style>.lfjsbubblemain .bubblehide {display: none !important;}.searchresult .bubblehide {display: none !important;}</style><div class="courseblock "> <p class="courseblocktitle noindent"><strong><span class="courseblockcode">MD GENET 911</span> — MODERN CLINICAL GENETICS: HOW TO APPROACH A RAPIDLY CHANGING FIELD</strong></p> <p class="courseblockcredits">2 credits.</p> <p class="courseblockdesc noindent"> Genetics and genomics are rapidly evolving fields. In modern clinical care settings, clinicians will be exposed to genetic and genomic data, including that brought by patients, and knowing how to read genetic and genomic data is increasingly necessary in clinical practice. Genetics and genomics in a clinical setting spans a wide range of topics including diagnosis and treatment of genetic diseases. Familiarity with clinical genetic analysis, and the genetic approaches used in basic science, helps medical students better understand genetic disease background. Learn how to bridge basic concepts of human genetics and clinical genetics (actual diseases). Emphases will include research into human genetic diseases, including designing genetic testing, using model organisms and/or cell culture systems, and the development of genetic testing technologies.<br/> </p> <button class="notinpdf cb-extras-toggle" aria-expanded="false" onclick="toggleCourseBlockInfo(this); return false;"><svg aria-hidden="true"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-caret-down"></use></svg>View details</button><div class="cb-extras" aria-hidden="true"><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Requisites: </strong></span></strong></span><span class="cbextra-data"><a href="/search/?P=MED%20SC-M%20810" title="MED SC-M 810" class="bubblelink code" onclick="return showCourse(this, 'MED SC-M 810');">MED SC-M 810</a>, <a href="/search/?P=MED%20SC-M%20811" title="MED SC-M 811" class="bubblelink code" onclick="return showCourse(this, 'MED SC-M 811');">811</a>, <a href="/search/?P=MED%20SC-M%20812" title="MED SC-M 812" class="bubblelink code" onclick="return showCourse(this, 'MED SC-M 812');">812</a>, and <a href="/search/?P=MED%20SC-M%20813" title="MED SC-M 813" class="bubblelink code" onclick="return showCourse(this, 'MED SC-M 813');">813</a></span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Course Designation: </strong></span></strong></span><span class="cbextra-data">Grad 50% - Counts toward 50% graduate coursework requirement</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Repeatable for Credit: </strong></span></strong></span><span class="cbextra-data">No</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Last Taught: </strong></span></strong></span><span class="cbextra-data">Spring 2023</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong></strong></span><span class="cbextra-data"><div class="bubblehide"><p class="courseblockextra noindent clearfix"><span class="cbextra-label"><strong>Learning Outcomes: </strong></span><span class="cbextra-data">1. Demonstrate understanding of basic concepts of human genetics<br/>Audience: Graduate<br/><br/>2. Describe various genetic approaches and models for studying human genetic diseases <br/>Audience: Graduate<br/><br/>3. Apply basic concepts of genetics to answering questions in human genetic diseases<br/>Audience: Graduate<br/><br/>4. Explain fundamentals of clinical genetics, including genetic testing<br/>Audience: Graduate<br/><br/>5. Model logical thinking process to organize scientific discussion and presentation <br/>Audience: Graduate</span></p></div></span></p></div></div><style>.lfjsbubblemain .bubblehide {display: none !important;}.searchresult .bubblehide {display: none !important;}</style><div class="courseblock "> <p class="courseblocktitle noindent"><strong><span class="courseblockcode">MD GENET 999</span> — INDEPENDENT WORK</strong></p> <p class="courseblockcredits">1-3 credits.</p> <p class="courseblockdesc noindent"> Directed study projects as arranged with instructor.<br/> </p> <button class="notinpdf cb-extras-toggle" aria-expanded="false" onclick="toggleCourseBlockInfo(this); return false;"><svg aria-hidden="true"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-caret-down"></use></svg>View details</button><div class="cb-extras" aria-hidden="true"><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Requisites: </strong></span></strong></span><span class="cbextra-data">Consent of instructor</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Course Designation: </strong></span></strong></span><span class="cbextra-data">Grad 50% - Counts toward 50% graduate coursework requirement</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Repeatable for Credit: </strong></span></strong></span><span class="cbextra-data">Yes, unlimited number of completions</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong><span class="cbextra-label"><strong>Last Taught: </strong></span></strong></span><span class="cbextra-data">Fall 2010</span></p><p class="courseblockextra noindent clearfix"><span class="cbextra=label"><strong></strong></span><span class="cbextra-data"><div class="bubblehide"><p class="courseblockextra noindent clearfix"><span class="cbextra-label"><strong>Learning Outcomes: </strong></span><span class="cbextra-data">1. Exhibit a broad understanding of general Genetics and Genomics principles. <br/>Audience: Graduate<br/><br/>2. Conduct advanced independent research using a variety of approaches.<br/>Audience: Graduate</span></p></div></span></p></div></div></div> </div> </div>  </div>  <div id="right-col"> <button class="tabs-expand" onclick="toggleTabs();"><svg aria-hidden="true"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-caret-down"></use></svg> Select a section…</button> <div id="print-options-box"> <button aria-expanded="false" aria-controls="print-options-list" data-toggle="#print-options-list"> <svg class="main-printer" viewBox="0 0 24 24" aria-hidden="true"> <path d="M18 3v3.984h-12v-3.984h12zM18.984 12c0.563 0 1.031-0.422 1.031-0.984s-0.469-1.031-1.031-1.031-0.984 0.469-0.984 1.031 0.422 0.984 0.984 0.984zM15.984 18.984v-4.969h-7.969v4.969h7.969zM18.984 8.016c1.641 0 3 1.359 3 3v6h-3.984v3.984h-12v-3.984h-3.984v-6c0-1.641 1.359-3 3-3h13.969z"></path> </svg> <span><span class="sr-only">Show </span>Print Options</span> <svg class="main-plus" viewBox="0 0 22 28" 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<symbol id="uw-symbol-caret-up" viewBox="0 0 1792 1792"> <title>Collapse</title> <path d="M1395 1184q0 13-10 23l-50 50q-10 10-23 10t-23-10l-393-393-393 393q-10 10-23 10t-23-10l-50-50q-10-10-10-23t10-23l466-466q10-10 23-10t23 10l466 466q10 10 10 23z"></path> </symbol> <symbol id="uw-symbol-caret-down" viewBox="0 0 1792 1792"> <title>Expand</title> <path d="M1395 736q0 13-10 23l-466 466q-10 10-23 10t-23-10l-466-466q-10-10-10-23t10-23l50-50q10-10 23-10t23 10l393 393 393-393q10-10 23-10t23 10l50 50q10 10 10 23z"></path> </symbol> <symbol id="uw-symbol-chevron-right" viewBox="0 0 695 1024"> <title id="svg-next-slide">next slide</title> <path class="path1" d="M632.571 501.143l-424 424q-10.857 10.857-25.714 10.857t-25.714-10.857l-94.857-94.857q-10.857-10.857-10.857-25.714t10.857-25.714l303.429-303.429-303.429-303.429q-10.857-10.857-10.857-25.714t10.857-25.714l94.857-94.857q10.857-10.857 25.714-10.857t25.714 10.857l424 424q10.857 10.857 10.857 25.714t-10.857 25.714z"></path> </symbol> <symbol 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