Nanomedicina

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<li class="nav-item"><a class="nav-link" href="https://spanish.scitechnol.com/journals/guidelines-regenerative-medicine.html" title="haga clic aqu铆">Pautas</a></li> <li class="nav-item"><a class="nav-link" href="https://spanish.scitechnol.com/journals/indexing-regenerative-medicine.html" title="haga clic aqu铆">Indexaci贸n y archivo</a></li> <li class="nav-item"><a class="nav-link" href="https://spanish.scitechnol.com/contact.html" title="haga clic aqu铆">Contacto</a></li> </ul> </div> </div> </nav> </header> <div class="bg-color-sky-light"> <div class="content-md container border-bottom-1"> <div class="row"> <div class="col-sm-9"> <div class="margin-b-30"> <h2>Nanomedicina</h2> <p style="text-align: justify;"><font style="vertical-align: inherit;"><font style="vertical-align: inherit;">En una conferencia de 1959 en Caltech, famosamente denominada "Hay mucho espacio en el fondo", el físico estadounidense y futuro premio Nobel Richard Feynman discutió la idea de manipular estructuras a nivel atómico. Aunque las aplicaciones que discutió eran teóricas en ese momento, sus ideas profetizaron el descubrimiento de muchas propiedades nuevas a escala nanométrica que no se observan en materiales a escalas mayores, allanando el camino para el campo en constante expansión de la nanomedicina. Hoy en día, el uso de materiales nanométricos, comparables en dimensiones a algunas proteínas, ADN, ARN y oligosacáridos, está causando sensación en diversos campos biomédicos, incluidos la biodetección, la obtención de imágenes, la administración de fármacos e incluso la cirugía.</font></font></p> <p style="text-align: justify;"><font style="vertical-align: inherit;"><font style="vertical-align: inherit;">Los nanomateriales suelen tener altas relaciones superficie-volumen, lo que genera un sustrato relativamente grande para la unión química. Los científicos han podido crear nuevas características superficiales para nanomateriales y han manipulado moléculas de recubrimiento para ajustar el comportamiento de las partículas. La mayoría de los nanomateriales también pueden penetrar en las células vivas, proporcionando la base para la administración de biosensores o terapias mediante nanoportadores. Cuando se administran sistémicamente, los nanomateriales son lo suficientemente pequeños como para no obstruir los vasos sanguíneos, pero son más grandes que muchos fármacos de molécula pequeña, lo que facilita un tiempo de retención prolongado en el sistema circulatorio. Con la capacidad de diseñar ADN sintético, los científicos ahora pueden diseñar y ensamblar nanoestructuras que aprovechen el emparejamiento de bases de Watson-Crick para mejorar la detección de objetivos y la administración de fármacos.</font></font></p> <p style="text-align: justify;"><font style="vertical-align: inherit;"><font style="vertical-align: inherit;">Tanto la comunidad académica como la industria farmacéutica están invirtiendo cada vez más tiempo y dinero en nanoterapéutica. Casi 50 productos biomédicos que incorporan nanopartículas ya están en el mercado, y muchos más están en proceso de elaboración, con docenas de ellos en ensayos clínicos de fase 2 o 3. Los fabricantes de medicamentos están en camino de hacer realidad la predicción de Christopher Guiffre, director comercial de Cerulean Pharma, empresa de nanoterapia con sede en Cambridge, Massachusetts, quien pronosticó en noviembre pasado: “Dentro de cinco años todas las empresas farmacéuticas tendrán un nanoprograma”.</font></font></p> </div> </div>  <div class="col-xs-12 col-md-3"> <div class="divider-v4 divider-v4-left-double bg-color-white padding-10 margin-b-10"> <h2 class="divider-v4-title">Explorar SciTechnol</h2> <div> <ul class="list-unstyled angle-right"> <li class="color-base"><a href="https://spanish.scitechnol.com/author-guidelines.html" title="haga clic aqu铆"> Pautas para el autor</a></li> <li class="color-base"><a href="https://spanish.scitechnol.com/reviewer-guidelines.html" title="haga clic aqu铆"> Directrices para el revisor</a></li> <li class="color-base"><a href="https://spanish.scitechnol.com/scitechnol-associations-indexing.html" title="haga clic aqu铆"> 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