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autopsy</title> <meta name="description" content="Search results for: autopsy"> <meta name="keywords" content="autopsy"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler ml-auto" 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class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="autopsy"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 50</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: autopsy</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">20</span> A Rare Neck Trauma by Bicycle Handlebar in Road Traffic Accident</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Parthasarathi%20Pramanik">Parthasarathi Pramanik</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Paediatric blunt abdominal trauma associated with superficial bruise, hematoma, or laceration and internal organ damage secondary to bicycle handlebar is widely documented in the literature. In this article, we have presented a case of bicycle handlebar inflicted fatal neck laceration in a road accident. The deceased sustained a horizontally placed laceration injury over the front and both sides of the middle third of neck (13 cm x 5-8 cm x 2-3.5 cm).The margins of the wound were irregular and focally abraded. The right corner of the injury was pointed whereas the left one was ended with a skin flap. Multiple graze abrasions, contusions and lacerations were found on different parts of body. Autopsy findings and other circumstantial evidences revealed that the victim died due to exsanguination because of severance of carotid artery and jugular vein of both sides. Analysis of the wound suggests the decease sustained the wound by the revolving bicycle handle bar while he had lost the balance. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bicycle%20handle%20bar" title="bicycle handle bar">bicycle handle bar</a>, <a href="https://publications.waset.org/abstracts/search?q=neck%20injury" title=" neck injury"> neck injury</a>, <a href="https://publications.waset.org/abstracts/search?q=lacerated%20injury" title=" lacerated injury"> lacerated injury</a>, <a href="https://publications.waset.org/abstracts/search?q=road%20acident" title=" road acident"> road acident</a> </p> <a href="https://publications.waset.org/abstracts/54465/a-rare-neck-trauma-by-bicycle-handlebar-in-road-traffic-accident" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/54465.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">317</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">19</span> The Development of Cardiac Tamponade after Spinal Surgery in a Patient with Duchenne Muscular Dystrophy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hacer%20Y.%20Teke">Hacer Y. Teke</a>, <a href="https://publications.waset.org/abstracts/search?q=Sultan%20Pehlivan"> Sultan Pehlivan</a>, <a href="https://publications.waset.org/abstracts/search?q=Mustafa%20Karap%C4%B1rl%C4%B1"> Mustafa Karapırlı</a>, <a href="https://publications.waset.org/abstracts/search?q=Asude%20G%C3%B6kmen"> Asude Gökmen</a>, <a href="https://publications.waset.org/abstracts/search?q=Sait%20%C3%96zsoy"> Sait Özsoy</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The case is here presented of a patient with DMD with electrocardiograph findings within normal limits who underwent spinal surgery then developed the rarely seen complication of cardiac tamponade which resulted in death. A 17-year old male with DMD was admitted to hospital for spinal surgery. Due to a postoperative drop in hemoglobin, blood transfusion was administered to the patient, no complication developed and he was discharged on the third day. Four days after discharge, the patient worsened at home and an ambulance was called. Before the nearest hospital was reached, the patient died in the ambulance. An autopsy was performed. A fatal but rarely seen complication of Acute Myocardial Infarction (AMI) is myocardial rupture. 85% of ruptures occur in the first week of AMI but just as they can be seen on the day of the infarct, they can also be seen 2 weeks later. The case presented here had infarction findings related to different times and in different areas. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=duchenne%20muscular%20dystrophy" title="duchenne muscular dystrophy">duchenne muscular dystrophy</a>, <a href="https://publications.waset.org/abstracts/search?q=myocardial%20infarction" title=" myocardial infarction"> myocardial infarction</a>, <a href="https://publications.waset.org/abstracts/search?q=myocardial%20rupture" title=" myocardial rupture"> myocardial rupture</a>, <a href="https://publications.waset.org/abstracts/search?q=anesthesia" title=" anesthesia"> anesthesia</a> </p> <a href="https://publications.waset.org/abstracts/29469/the-development-of-cardiac-tamponade-after-spinal-surgery-in-a-patient-with-duchenne-muscular-dystrophy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/29469.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">482</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18</span> Pathology of the Partridge Gambra Alectoris barbara in a Semi-Captive Breeding in the Algiers Sahel</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=H.%20Saadi-Idouhar">H. Saadi-Idouhar</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Smai"> A. Smai</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Zenia"> S. Zenia</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Haddadj"> F. Haddadj</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Saadi"> A. Saadi</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Aissi"> M. Aissi</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Doumandji"> S. Doumandji</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In Algeria, the Partridge gambra is a highly sought-after game species and is appreciated for its meat. Game birds are of interest because they play an important role for hunting federations and for the economy of a country. The breeding of indigenous breeds is necessary because it is of great economic interest. However, gambra breeding in the hunting centre of Zeralda (northern west of Algiers) is not easy, several diseases affecting Perdreaux and reproducing adults have been noted. Most of the diseases observed are parasitic in origin. This study is conducted during the 2010 breeding season. It is based on the autopsy of cadavers collected at the hunting centre and parasitic coprology. Indeed, the flotation enrichment method has identified several parasites such as Eimeria spp., Capillaria spp., and Ascaridia spp. Autopsied corpses show the importance of two major diseases, syngamosis caused to Syngamus trachea and histomonosis caused to Histomonas meleagridis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=partridge" title="partridge">partridge</a>, <a href="https://publications.waset.org/abstracts/search?q=livestock" title=" livestock"> livestock</a>, <a href="https://publications.waset.org/abstracts/search?q=eggs" title=" eggs"> eggs</a>, <a href="https://publications.waset.org/abstracts/search?q=affections%20pathology" title=" affections pathology"> affections pathology</a> </p> <a href="https://publications.waset.org/abstracts/101106/pathology-of-the-partridge-gambra-alectoris-barbara-in-a-semi-captive-breeding-in-the-algiers-sahel" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/101106.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">180</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17</span> Alteration of Sex Steroid Hormone Levels in Sex Reversed Chickens</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20H.%20Shaikat">A. H. Shaikat</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20B.%20Hossain"> M. B. Hossain</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20K.%20M.%20A.%20Islam"> S. K. M. A. Islam</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20M.%20Hassan"> M. M. Hassan</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20A.%20Khan"> S. A. Khan</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20K.%20M.%20Saifuddin"> A. K. M. Saifuddin</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20N.%20Islam"> M. N. Islam</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20A.%20Hoque"> M. A. Hoque</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A total of eighteen (18) sex reversed chickens with unusual phenotypic characteristics of male birds were identified over 2000 Hyline layer chickens at Motaher Poultry Farm, Ramu, Cox’s Bazar. Chickens were subdivided into two groups (case = 18, control = 20) based on the appearance of sex-reversed secondary sexual characteristics. Phenotypic traits of studied chickens were measured with farm management details. Hormone assay using ELISA, autopsy followed by gross examination of viscera was performed. The study found higher body weight (gm) (1579.3; 95% CI: 1561.7-1596.8), comb length (cm) (12.2; 11.5-12.8), comb width (cm) (7.9; 7.7-8.2), wattle length (cm) (4.9; 4.8-5.1) distinct spur, and shortened pubic bones distance, suggesting decrease oviposition in sex-reversed chickens. Testosterone concentration (ng/ml) (8.5; 6.4-10.6) was significantly higher (p<0.001) along with decrease estrogen (pg/ml) (5.1; 4.9-5.5) and progesterone concentration (pg/ml) (310.9; 289.4-332.5) in sex-reversed chickens. Mass abdominal fat deposition with atrophied ovary was found upon exploration of viscera. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ovary" title="ovary">ovary</a>, <a href="https://publications.waset.org/abstracts/search?q=phenotypic%20traits" title=" phenotypic traits"> phenotypic traits</a>, <a href="https://publications.waset.org/abstracts/search?q=sex%20hormone" title=" sex hormone"> sex hormone</a>, <a href="https://publications.waset.org/abstracts/search?q=sex%20reversal" title=" sex reversal"> sex reversal</a> </p> <a href="https://publications.waset.org/abstracts/1765/alteration-of-sex-steroid-hormone-levels-in-sex-reversed-chickens" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/1765.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">447</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">16</span> Choking among Infants and Young Children</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Emad%20M.Abdullat">Emad M.Abdullat</a>, <a href="https://publications.waset.org/abstracts/search?q=Hasan%20A.%20Ader-Rahman"> Hasan A. Ader-Rahman</a>, <a href="https://publications.waset.org/abstracts/search?q=Rayyan%20Al%20Ali"> Rayyan Al Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=Arwa.A.Hudaib"> Arwa.A.Hudaib</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This retrospective study aims to determine the epidemiological features of such deaths in one of the general teaching hospitals in Jordan with a focus on weaning practices and its relation to sucking as major factors underlying the mechanism of choking in infants and young children. The study utilized a retrospective design to review the records of forensic cases due to foreign body aspiration examined at the forensic department at the Jordan University Hospital. A total of 27 cases of choking in the pediatric age group were retrieved from the reports of the autopsy cases dissected. All cases of children who died due to chocking by foreign bodies were under 11 years old. Choking by food materials constituted (44.4%) of cases under 3 years of age while choking by non-food material were less prevalent under 3 years of age and comprising 18.5% of the cases. Health care personnel and parents need to be aware that introduction of solid food, unlike exclusive breast or formula-milk feeding, can have serious consequences if occurring in inappropriate timing or consistency during early childhood physical and functional development. Parents need to be educated regarding the appropriate timing and process of weaning. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chocking" title="chocking">chocking</a>, <a href="https://publications.waset.org/abstracts/search?q=infants" title=" infants"> infants</a>, <a href="https://publications.waset.org/abstracts/search?q=weaning%20practices" title=" weaning practices"> weaning practices</a>, <a href="https://publications.waset.org/abstracts/search?q=young%20children" title=" young children"> young children</a> </p> <a href="https://publications.waset.org/abstracts/33342/choking-among-infants-and-young-children" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/33342.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">488</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">15</span> Postmortem Analysis of Lidocaine in Women Died of Criminal Abortion</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohammed%20A.%20Arishy">Mohammed A. Arishy</a>, <a href="https://publications.waset.org/abstracts/search?q=Sultan%20M.%20Alharbi"> Sultan M. Alharbi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammed%20A.%20Hakami"> Mohammed A. Hakami</a>, <a href="https://publications.waset.org/abstracts/search?q=Farid%20M.%20Abualsail"> Farid M. Abualsail</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20A.%20Attafi"> Mohammad A. Attafi</a>, <a href="https://publications.waset.org/abstracts/search?q=Riyadh%20M.%20Tobaiqi"> Riyadh M. Tobaiqi</a>, <a href="https://publications.waset.org/abstracts/search?q=Hussain%20M.%20Alsalem"> Hussain M. Alsalem</a>, <a href="https://publications.waset.org/abstracts/search?q=Ibraheem%20M.%20Attafi"> Ibraheem M. Attafi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Lidocaine is the most common local anesthetics used for para cervical block to reduce pain associated with surgical abortion. A 25-year-old pregnant woman who. She died before reaching hospital, and she was undergoing criminal abortion during the first trimester. In post-mortem investigations and autopsy shows no clear finding; therefore, toxic substances must be suspected and searched for routinely toxicology analysis. In this case report, the postmortem concentration of lidocaine was detected blood, brain, liver, kidney, and stomach. For lidocaine identification and quantification, sample was extracted using solid phase extraction and analyzed by GC-MS (Shimadzu, Japan). Initial screening and confirmatory analysis results showed that only lidocaine was detected in all collected samples, and no other toxic substances or alcohol were detected. The concentrations of lidocaine in samples were 19, 17, 14, 7, and 3 ug/m in the brain, blood, kidney, liver, and stomach, respectively. Lidocaine blood concentration (17 ug/ml) was toxic level and may result in death. Among the tissues, brain showed the highest level of lidocaine, followed by the kidney, liver, and stomach. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=forensic%20toxicology" title="forensic toxicology">forensic toxicology</a>, <a href="https://publications.waset.org/abstracts/search?q=GC-MS" title=" GC-MS"> GC-MS</a>, <a href="https://publications.waset.org/abstracts/search?q=lidocaine" title=" lidocaine"> lidocaine</a>, <a href="https://publications.waset.org/abstracts/search?q=postmortem" title=" postmortem"> postmortem</a> </p> <a href="https://publications.waset.org/abstracts/112713/postmortem-analysis-of-lidocaine-in-women-died-of-criminal-abortion" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/112713.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">210</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14</span> Forensic Necropsy-Importance in Wildlife Conservation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=G.%20V.%20Sai%20Soumya">G. V. Sai Soumya</a>, <a href="https://publications.waset.org/abstracts/search?q=Kalpesh%20Solanki"> Kalpesh Solanki</a>, <a href="https://publications.waset.org/abstracts/search?q=Sumit%20K.%20Choudhary"> Sumit K. Choudhary</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Necropsy is another term used for an autopsy, which is known as death examination in the case of animals. It is a complete standardized procedure involving dissection, observation, interpretation, and documentation. Government Bodies like National Tiger Conservation Authority (NTCA) have given standard operating procedures for commencing the necropsies. Necropsies are rarely performed as compared to autopsies performed on human bodies. There are no databases which maintain the count of autopsies in wildlife, but the research in this area has shown a very small number of necropsies. Long back, wildlife forensics came into existence but is coming into light nowadays as there is an increase in wildlife crime cases, including the smuggling of trophies, pooching, and many more. Physical examination in cases of animals is not sufficient to yield fruitful information, and thus postmortem examination plays an important role. Postmortem examination helps in the determination of time since death, cause of death, manner of death, factors affecting the case under investigation, and thus decreases the amount of time required in solving cases. Increasing the rate of necropsies will help forensic veterinary pathologists to build standardized provision and confidence within them, which will ultimately yield a higher success rate in solving wildlife crime cases. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=necropsy" title="necropsy">necropsy</a>, <a href="https://publications.waset.org/abstracts/search?q=wildlife%20crime" title=" wildlife crime"> wildlife crime</a>, <a href="https://publications.waset.org/abstracts/search?q=postmortem%20examination" title=" postmortem examination"> postmortem examination</a>, <a href="https://publications.waset.org/abstracts/search?q=forensic%20application" title=" forensic application"> forensic application</a> </p> <a href="https://publications.waset.org/abstracts/131708/forensic-necropsy-importance-in-wildlife-conservation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/131708.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">139</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">13</span> Analysis of Brain Specific Creatine Kinase of Postmortem Cerebrospinal Fluid and Serum in Blunt Head Trauma Cases</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rika%20Susanti">Rika Susanti</a>, <a href="https://publications.waset.org/abstracts/search?q=Eryati%20Darwin"> Eryati Darwin</a>, <a href="https://publications.waset.org/abstracts/search?q=Dedi%20Afandi"> Dedi Afandi</a>, <a href="https://publications.waset.org/abstracts/search?q=Yanwirasti"> Yanwirasti</a>, <a href="https://publications.waset.org/abstracts/search?q=Syahruddin%20Said"> Syahruddin Said</a>, <a href="https://publications.waset.org/abstracts/search?q=Noverika%20Windasari"> Noverika Windasari</a>, <a href="https://publications.waset.org/abstracts/search?q=Zelly%20Dia%20Rofinda"> Zelly Dia Rofinda</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Blunt head trauma is one of the leading causes of death associated with murders and other deaths involved in criminal acts. Creatine kinase (CKBB) levels have been used as a biomarker for blunt head trauma. Therefore, it is now used as an alternative to an autopsy. The aim of this study is to investigate CKBB levels in cerebrospinal fluid (CSF) and post-mortem serum in order to deduce the cause and time of death. Method: This investigation was conducted through post-test–only group design involving deaths caused by blunt head trauma, which was compared to deaths caused by ketamine poisoning. Results: There were eight treatment groups, each consisting of six adult rats (Rattus norvegicus) Sprague-Dawley strain. Examinations were done at 0 hours, 1 hour, 2 hours, and 3 hours post-mortem, which followed by brain tissue observation. Data were then analyzed statistically with a repeated-measures general linear model. Conclusion: There were increases in the level of CKBB in CSF and postmortem serum in both blunt head trauma and ketamine poisoning treatment groups. However, there were no significant differences between these two groups. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=blunt%20head%20trauma" title="blunt head trauma">blunt head trauma</a>, <a href="https://publications.waset.org/abstracts/search?q=CKBB" title=" CKBB"> CKBB</a>, <a href="https://publications.waset.org/abstracts/search?q=the%20cause%20of%20death" title=" the cause of death"> the cause of death</a>, <a href="https://publications.waset.org/abstracts/search?q=estimated%20time%20of%20death" title=" estimated time of death"> estimated time of death</a> </p> <a href="https://publications.waset.org/abstracts/86063/analysis-of-brain-specific-creatine-kinase-of-postmortem-cerebrospinal-fluid-and-serum-in-blunt-head-trauma-cases" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/86063.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">192</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">12</span> A Retrospective Study of Suicidal Deaths in Madinah for Ten Years</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Radah%20Yousuf">Radah Yousuf</a>, <a href="https://publications.waset.org/abstracts/search?q=Ashraf%20Shebl"> Ashraf Shebl</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Suicide is a tragic event with strong emotional repercussions for its survivors and for families of its victims. There were thousands of cases all over the world. There are many risk factors include mental disorders such as depression, and substance abuse, including alcoholism and use of benzodiazepines. Other suicides are impulsive acts due to stress such as from financial difficulties, troubles with relationships, or from bullying. The aim of work in this study is making a survey from archives of the suicidal cases, which had a medicolegal examination, in forensic medicine center in Al Madinah Almunawarah-KSA, for ten years in the period between 1428-1438h. In each case, some data are collected such as age, sex, time and place of an act, method of suicide, the presence of the witness, medical history. This study demonstrates that suicide is more common in male than female, and the 4th decade was the most period of age. The most common method of suicide was hanging followed by falling from the height. These results indicated that cultural and religious beliefs that discourage suicide and support self-preservation instinct, and suicide education programs provide information to students in high school, builds awareness, one of the most important issues in solving that problem. From the forensic view, circumstantial evidence of every forensic case must take and record, full history about the social, medical and psychological problems, attend the scene of death is a very important, complete medicolegal investigation for every case, and full autopsy with very skilled techniques and facilities can help in diagnosing what type of crimes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=suicide" title="suicide">suicide</a>, <a href="https://publications.waset.org/abstracts/search?q=age" title=" age"> age</a>, <a href="https://publications.waset.org/abstracts/search?q=sex" title=" sex"> sex</a>, <a href="https://publications.waset.org/abstracts/search?q=hanging" title=" hanging"> hanging</a> </p> <a href="https://publications.waset.org/abstracts/88955/a-retrospective-study-of-suicidal-deaths-in-madinah-for-ten-years" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/88955.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">148</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">11</span> Diagnostic Value of Different Noninvasive Criteria of Latent Myocarditis in Comparison with Myocardial Biopsy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Olga%20Blagova">Olga Blagova</a>, <a href="https://publications.waset.org/abstracts/search?q=Yuliya%20Osipova"> Yuliya Osipova</a>, <a href="https://publications.waset.org/abstracts/search?q=Evgeniya%20Kogan"> Evgeniya Kogan</a>, <a href="https://publications.waset.org/abstracts/search?q=Alexander%20Nedostup"> Alexander Nedostup</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: to quantify the value of various clinical, laboratory and instrumental signs in the diagnosis of myocarditis in comparison with morphological studies of the myocardium. Methods: in 100 patients (65 men, 44.7±12.5 years) with «idiopathic» arrhythmias (n = 20) and dilated cardiomyopathy (DCM, n = 80) were performed 71 endomyocardial biopsy (EMB), 13 intraoperative biopsy, 5 study of explanted hearts, 11 autopsy with virus investigation (real-time PCR) of the blood and myocardium. Anti-heart antibodies (AHA) were also measured as well as cardiac CT (n = 45), MRI (n = 25), coronary angiography (n = 47). The comparison group included of 50 patients (25 men, 53.7±11.7 years) with non-inflammatory heart diseases who underwent open heart surgery. Results. Active/borderline myocarditis was diagnosed in 76.0% of the study group and in 21.6% of patients of the comparison group (p < 0.001). The myocardial viral genome was observed more frequently in patients of comparison group than in study group (group (65.0% and 40.2%; p < 0.01. Evaluated the diagnostic value of noninvasive markers of myocarditis. The panel of anti-heart antibodies had the greatest importance to identify myocarditis: sensitivity was 81.5%, positive and negative predictive value was 75.0 and 60.5%. It is defined diagnostic value of non-invasive markers of myocarditis and diagnostic algorithm providing an individual assessment of the likelihood of myocarditis is developed. Conclusion. The greatest significance in the diagnosis of latent myocarditis in patients with 'idiopathic' arrhythmias and DCM have AHA. The use of complex of noninvasive criteria allows estimate the probability of myocarditis and determine the indications for EMB. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=myocarditis" title="myocarditis">myocarditis</a>, <a href="https://publications.waset.org/abstracts/search?q=%22idiopathic%22%20arrhythmias" title=" "idiopathic" arrhythmias"> "idiopathic" arrhythmias</a>, <a href="https://publications.waset.org/abstracts/search?q=dilated%20cardiomyopathy" title=" dilated cardiomyopathy"> dilated cardiomyopathy</a>, <a href="https://publications.waset.org/abstracts/search?q=endomyocardial%20biopsy" title=" endomyocardial biopsy"> endomyocardial biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=viral%20genome" title=" viral genome"> viral genome</a>, <a href="https://publications.waset.org/abstracts/search?q=anti-heart%20antibodies" title=" anti-heart antibodies"> anti-heart antibodies</a> </p> <a href="https://publications.waset.org/abstracts/83648/diagnostic-value-of-different-noninvasive-criteria-of-latent-myocarditis-in-comparison-with-myocardial-biopsy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/83648.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">173</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10</span> Credible Autopsy Report for Investigators and Judiciary</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sudhir%20K.%20Gupta">Sudhir K. Gupta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: When a forensic doctor determines that a suspicious death is a suicide, homicide, or accident, the decision virtually becomes incontestable by the investigating police officer, and it becomes an issue whether the medical opinion was created with necessary checks and balances on the other probabilities of the case. It is suggested that the opinion of Forensic Medical experts is conventional, mutable, and shifting from one expert to another. The determination of suicide, accident, or homicide is mandatorily required, which is the Gold Standard for conducting death investigations. Forensic investigations serve many audiences, but the court is by far the most critical. The likely questions on direct and cross-examination determine how forensic doctors gather and handle evidence and what conclusions they reach. Methodology: The author interacted with the investigative authority, and a crime scene visit was also done along with the perusal of the Postmortem report, subsequent opinion, and crime scene photographs and statements of the witness and accused. Further analysis of all relevant scientific documents and opinions of other forensic doctors, forensic scientists, and ballistic experts involved in these cases was done to arrive at an opinion with scientific justification. Findings: The opinions arrived at by the author and how they helped the judiciary in delivering justice in these cases have been discussed in this article. This can help the readers to understand the process involved in formulating a credible forensic medical expert opinion for investigators and the judiciary. Conclusion: A criminal case might be won or lost over doubt cast on the chain of custody. Medically trained forensic doctors, therefore, learn to practice their profession in legally appropriate ways, and opinions must be based on medical justifications with credible references. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=forensic%20doctor" title="forensic doctor">forensic doctor</a>, <a href="https://publications.waset.org/abstracts/search?q=professional%20credibility" title=" professional credibility"> professional credibility</a>, <a href="https://publications.waset.org/abstracts/search?q=investigation" title=" investigation"> investigation</a>, <a href="https://publications.waset.org/abstracts/search?q=expert%20opinion" title=" expert opinion"> expert opinion</a> </p> <a href="https://publications.waset.org/abstracts/156415/credible-autopsy-report-for-investigators-and-judiciary" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/156415.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">76</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9</span> The Effect of Jujube Extract and Resistance Training on the Reduction of Complications Caused by the Induction of Anabolic Steroid Boldenone on the Histopathological Changes of Pancreatic Tissue of Male Wistar Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sayyed-javad%20Ziaolhagh">Sayyed-javad Ziaolhagh</a>, <a href="https://publications.waset.org/abstracts/search?q=Ali-Reza%20Saadatifar"> Ali-Reza Saadatifar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Athletes frequently perform anabolic steroid resistance exercise, but the effects of medical doses and abuse along with resistance exercise on structural damage to the Pancreases and also jujube extract are unknown. The aim of this study was to investigate the effects of resistance training on body weight and hip fractures induced by boldenone injection in male rats. Materials and methods: In this experimental study, 30 male Wistar rats aged 8-12 weeks (weight 202±9.34 g) were randomly divided into five groups: control, boldenone, extract of iujuba+boldenone, boldenone+resistance training and boldenone+resistance training +extract of jujuba. The resistance training program included climbing the ladder for 8 weeks, 3 days a week, 1 session training in a day and each session consisted of the 3 sets and 5 repetitions. Injection was conducted in depth in the hamstring once a week on an appointed day. After anesthesia, autopsy was performed, and the cardiac tissue was isolated. Results: Results showed that boldenone caused tissue damage, congestion, and nuclei unclear and diffuse. In the group "resistance + Boldenone," The Pancreases tissue showed a high degree of hyperemia, and the muscle cells were somewhat abnormal. In boldenone + jujube, the appearance of the tissue was normal, and the rejuvenating effect was visible. Conclusion: Boldenone appears to cause structural damage to the Pancreases tissue. Strength training with Jujube Extract can reduce part of the pancreatic system disorders (necrosis and inflammation) caused by anabolic steroid use. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=boldenone" title="boldenone">boldenone</a>, <a href="https://publications.waset.org/abstracts/search?q=Jujube%20extract" title=" Jujube extract"> Jujube extract</a>, <a href="https://publications.waset.org/abstracts/search?q=pancreases%20tissue" title=" pancreases tissue"> pancreases tissue</a>, <a href="https://publications.waset.org/abstracts/search?q=resistance%20training" title=" resistance training"> resistance training</a> </p> <a href="https://publications.waset.org/abstracts/168411/the-effect-of-jujube-extract-and-resistance-training-on-the-reduction-of-complications-caused-by-the-induction-of-anabolic-steroid-boldenone-on-the-histopathological-changes-of-pancreatic-tissue-of-male-wistar-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/168411.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">70</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> Analysis of Maternal Death Surveillance and Response: Causes and Contributing Factors in Addis Ababa, Ethiopia, 2022</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sisay%20Tiroro%20Salato">Sisay Tiroro Salato</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Ethiopia has been implementing the maternal death surveillance and response system to provide real-time actionable information, including causes of death and contributing factors. Analysis of maternal mortality surveillance data was conducted to identify the causes and underlying factors in Addis Ababa, Ethiopia. Methods: We carried out a retrospective surveillance data analysis of 324 maternal deaths reported in Addis Ababa, Ethiopia, from 2017 to 2021. The data were extracted from the national maternal death surveillance and response database, including information from case investigation, verbal autopsy, and facility extraction forms. The data were analyzed by computing frequency and presented in numbers, proportions, and ratios. Results: Of 324 maternal deaths, 92% died in the health facilities, 6.2% in transit, and 1.5% at home. The mean age at death was 28 years, ranging from 17 to 45. The maternal mortality ratio per 100,000 live births was 77for the five years, ranging from 126 in 2017 to 21 in 2021. The direct and indirect causes of death were responsible for 87% and 13%, respectively. The direct causes included obstetric haemorrhage, hypertensive disorders in pregnancy, puerperal sepsis, embolism, obstructed labour, and abortion. The third delay (delay in receiving care after reaching health facilities) accounted for 57% of deaths, while the first delay (delay in deciding to seek health care) and the second delay (delay in reaching health facilities) and accounted for 34% and 24%, respectively. Late arrival to the referral facility, delayed management after admission, andnon-recognition of danger signs were underlying factors. Conclusion: Over 86% of maternal deaths were attributed by avoidable direct causes. The majority of women do try to reach health services when an emergency occurs, but the third delays present a major problem. Improving the quality of care at the healthcare facility level will help to reduce maternal death. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=maternal%20death" title="maternal death">maternal death</a>, <a href="https://publications.waset.org/abstracts/search?q=surveillance" title=" surveillance"> surveillance</a>, <a href="https://publications.waset.org/abstracts/search?q=delays" title=" delays"> delays</a>, <a href="https://publications.waset.org/abstracts/search?q=factors" title=" factors"> factors</a> </p> <a href="https://publications.waset.org/abstracts/154084/analysis-of-maternal-death-surveillance-and-response-causes-and-contributing-factors-in-addis-ababa-ethiopia-2022" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/154084.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">113</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> History of Pediatric Renal Pathology</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Elbaba">Mostafa Elbaba</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Because childhood renal diseases are grossly different compared to adult diseases, pediatric nephrology was founded as a specialty in 1965. Renal pathology specialty was introduced at the London Ciba Symposium in 1961. The history of renal pathology can be divided into two eras: one starting in the 1650s with the invention of the microscope, the second in the 1950s with the implementation of renal biopsy, and the presence of electron microscopy and immunofluorescence study. Prior to the 1950s, the study of diseased human kidneys was restricted to postmortem examination by gross pathology. In 1827, Richard Bright first described his triad of kidney disease, which was confirmed by morbid kidney changes at autopsy. In 1905 Friedrich Mueller coined the term “nephrosis” describing the inflammatory form of “degenerative” diseases, and later F. Munk added the term “lipoid nephrosis”. The most profound influence on renal diseases’ classification came from the publication of Volhard and Fahr in 1914. In 1899, Carl Max Wilhelm Wilms described Wilms' tumor of the kidneys in children. Chronic pyelonephritis was a popular renal diagnosis and the most common cause of uremia until the 1960s. Although kidney biopsy had been used early in the 1930s for renal tumors, the earliest reports of its use in the diagnosis of medical kidney disease were by Iversen and Brun in 1951, followed by Alwall in 1952, then by Pardo in 1953. The earliest intentional renal biopsies were done in 1944 by Nils Alwall, while the procedure was abandoned after the death of one of his 13 patients who biopsied. In 1950, Antonino Perez-Ara attempted renal biopsies, but his results were missed because of an unpopular journal publication. In the year 1951, Claus Brun and Poul Iverson developed the biopsy procedure using an aspiration technique. Popularizing renal biopsy practice is accredited to Robert Kark, who published his distinct work in 1954. He perfected the technique of renal biopsy in the prone position using the Vim-Silverman needle and used intravenous pyelography to improve the localization of the kidney. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=history" title="history">history</a>, <a href="https://publications.waset.org/abstracts/search?q=medicine" title=" medicine"> medicine</a>, <a href="https://publications.waset.org/abstracts/search?q=nephrology" title=" nephrology"> nephrology</a>, <a href="https://publications.waset.org/abstracts/search?q=pediatrics" title=" pediatrics"> pediatrics</a>, <a href="https://publications.waset.org/abstracts/search?q=pathology" title=" pathology"> pathology</a> </p> <a href="https://publications.waset.org/abstracts/173746/history-of-pediatric-renal-pathology" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/173746.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">59</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> Optical Coherence Tomography in Parkinson’s Disease: A Potential in-vivo Retinal α-Synuclein Biomarker in Parkinson’s Disease</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jessica%20Chorostecki">Jessica Chorostecki</a>, <a href="https://publications.waset.org/abstracts/search?q=Aashka%20Shah"> Aashka Shah</a>, <a href="https://publications.waset.org/abstracts/search?q=Fen%20Bao"> Fen Bao</a>, <a href="https://publications.waset.org/abstracts/search?q=Ginny%20Bao"> Ginny Bao</a>, <a href="https://publications.waset.org/abstracts/search?q=Edwin%20George"> Edwin George</a>, <a href="https://publications.waset.org/abstracts/search?q=Navid%20Seraji-Bozorgzad"> Navid Seraji-Bozorgzad</a>, <a href="https://publications.waset.org/abstracts/search?q=Veronica%20Gorden"> Veronica Gorden</a>, <a href="https://publications.waset.org/abstracts/search?q=Christina%20Caon"> Christina Caon</a>, <a href="https://publications.waset.org/abstracts/search?q=Elliot%20Frohman"> Elliot Frohman</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Parkinson’s Disease (PD) is a neuro degenerative disorder associated with the loss of dopaminergic cells and the presence α-synuclein (AS) aggregation in of Lewy bodies. Both dopaminergic cells and AS are found in the retina. Optical coherence tomography (OCT) allows high-resolution in-vivo examination of retinal structure injury in neuro degenerative disorders including PD. Methods: We performed a cross-section OCT study in patients with definite PD and healthy controls (HC) using Spectral Domain SD-OCT platform to measure the peripapillary retinal nerve fiber layer (pRNFL) thickness and total macular volume (TMV). We performed intra-retinal segmentation with fully automated segmentation software to measure the volume of the RNFL, ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), and the outer nuclear layer (ONL). Segmentation was performed blinded to the clinical status of the study participants. Results: 101 eyes from 52 PD patients (mean age 65.8 years) and 46 eyes from 24 HC subjects (mean age 64.1 years) were included in the study. The mean pRNFL thickness was not significantly different (96.95 μm vs 94.42 μm, p=0.07) but the TMV was significantly lower in PD compared to HC (8.33 mm3 vs 8.58 mm3 p=0.0002). Intra-retinal segmentation showed no significant difference in the RNFL volume between the PD and HC groups (0.95 mm3 vs 0.92 mm3 p=0.454). However, GCL, IPL, INL, and ONL volumes were significantly reduced in PD compared to HC. In contrast, the volume of OPL was significantly increased in PD compared to HC. Conclusions: Our finding of the enlarged OPL corresponds with mRNA expression studies showing localization of AS in the OPL across vertebrate species and autopsy studies demonstrating AS aggregation in the deeper layers of retina in PD. We propose that the enlargement of the OPL may represent a potential biomarker of AS aggregation in PD. Longitudinal studies in larger cohorts are warranted to confirm our observations that may have significant implications in disease monitoring and therapeutic development. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Optical%20Coherence%20Tomography" title="Optical Coherence Tomography">Optical Coherence Tomography</a>, <a href="https://publications.waset.org/abstracts/search?q=biomarker" title=" biomarker"> biomarker</a>, <a href="https://publications.waset.org/abstracts/search?q=Parkinson%27s%20disease" title=" Parkinson's disease"> Parkinson's disease</a>, <a href="https://publications.waset.org/abstracts/search?q=alpha-synuclein" title=" alpha-synuclein"> alpha-synuclein</a>, <a href="https://publications.waset.org/abstracts/search?q=retina" title=" retina"> retina</a> </p> <a href="https://publications.waset.org/abstracts/21182/optical-coherence-tomography-in-parkinsons-disease-a-potential-in-vivo-retinal-a-synuclein-biomarker-in-parkinsons-disease" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21182.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">437</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> The Interventricular Septum as a Site for Implantation of Electrocardiac Devices - Clinical Implications of Topography and Variation in Position</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Marcin%20Jakiel">Marcin Jakiel</a>, <a href="https://publications.waset.org/abstracts/search?q=Maria%20Kurek"> Maria Kurek</a>, <a href="https://publications.waset.org/abstracts/search?q=Karolina%20Gutkowska"> Karolina Gutkowska</a>, <a href="https://publications.waset.org/abstracts/search?q=Sylwia%20Sanakiewicz"> Sylwia Sanakiewicz</a>, <a href="https://publications.waset.org/abstracts/search?q=Dominika%20Stolarczyk"> Dominika Stolarczyk</a>, <a href="https://publications.waset.org/abstracts/search?q=Jakub%20Batko"> Jakub Batko</a>, <a href="https://publications.waset.org/abstracts/search?q=Rafa%C5%82%20Jakiel"> Rafał Jakiel</a>, <a href="https://publications.waset.org/abstracts/search?q=Mateusz%20K.%20Ho%C5%82da"> Mateusz K. Hołda</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Proper imaging of the interventricular septum during endocavital lead implantation is essential for successful procedure. The interventricular septum is located oblique to the 3 main body planes and forms angles of 44.56° ± 7.81°, 45.44° ± 7.81°, 62.49° (IQR 58.84° - 68.39°) with the sagittal, frontal and transverse planes, respectively. The optimal left anterior oblique (LAO) projection is to have the septum aligned along the radiation beam and will be obtained for an angle of 53.24° ± 9,08°, while the best visualization of the septal surface in the right anterior oblique (RAO) projection is obtained by using an angle of 45.44° ± 7.81°. In addition, the RAO angle (p=0.003) and the septal slope to the transverse plane (p=0.002) are larger in the male group, but the LAO angle (p=0.003) and the dihedral angle that the septum forms with the sagittal plane (p=0.003) are smaller, compared to the female group. Analyzing the optimal RAO angle in cross-sections lying at the level of the connections of the septum with the free wall of the right ventricle from the front and back, we obtain slightly smaller angle values, i.e. 41.11° ± 8.51° and 43.94° ± 7.22°, respectively. As the septum is directed leftward in the apical region, the optimal RAO angle for this area decreases (16.49° ± 7,07°) and does not show significant differences between the male and female groups (p=0.23). Within the right ventricular apex, there is a cavity formed by the apical segment of the interventricular septum and the free wall of the right ventricle with a depth of 12.35mm (IQR 11.07mm - 13.51mm). The length of the septum measured in longitudinal section, containing 4 heart cavities, is 73.03mm ± 8.06mm. With the left ventricular septal wall formed by the interventricular septum in the apical region at a length of 10.06mm (IQR 8.86 - 11.07mm) already lies outside the right ventricle. Both mentioned lengths are significantly larger in the male group (p<0.001). For proper imaging of the septum from the right ventricular side, an oblique position of the visualization devices is necessary. Correct determination of the RAO and LAO angle during the procedure allows to improve the procedure performed, and possible modification of the visual field when moving in the anterior, posterior and apical directions of the septum will avoid complications. Overlooking the change in the direction of the interventricular septum in the apical region and a significant decrease in the RAO angle can result in implantation of the lead into the free wall of the right ventricle with less effective pacing and even complications such as wall perforation and cardiac tamponade. The demonstrated gender differences can also be helpful in setting the right projections. A necessary addition to the analysis will be a description of the area of the ventricular septum, which we are currently working on using autopsy material. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anatomical%20variability" title="anatomical variability">anatomical variability</a>, <a href="https://publications.waset.org/abstracts/search?q=angle" title=" angle"> angle</a>, <a href="https://publications.waset.org/abstracts/search?q=electrocardiological%20procedure" title=" electrocardiological procedure"> electrocardiological procedure</a>, <a href="https://publications.waset.org/abstracts/search?q=intervetricular%20septum" title=" intervetricular septum"> intervetricular septum</a> </p> <a href="https://publications.waset.org/abstracts/154227/the-interventricular-septum-as-a-site-for-implantation-of-electrocardiac-devices-clinical-implications-of-topography-and-variation-in-position" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/154227.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">99</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> The Effect of Elapsed Time on the Cardiac Troponin-T Degradation and Its Utility as a Time Since Death Marker in Cases of Death Due to Burn</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sachil%20Kumar">Sachil Kumar</a>, <a href="https://publications.waset.org/abstracts/search?q=Anoop%20K.Verma"> Anoop K.Verma</a>, <a href="https://publications.waset.org/abstracts/search?q=Uma%20Shankar%20Singh"> Uma Shankar Singh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> It’s extremely important to study postmortem interval in different causes of death since it assists in a great way in making an opinion on the exact cause of death following such incident often times. With diligent knowledge of the interval one could really say as an expert that the cause of death is not feigned hence there is a great need in evaluating such death to have been at the CRIME SCENE before performing an autopsy on such body. The approach described here is based on analyzing the degradation or proteolysis of a cardiac protein in cases of deaths due to burn as a marker of time since death. Cardiac tissue samples were collected from (n=6) medico-legal autopsies, (Department of Forensic Medicine and Toxicology), King George’s Medical University, Lucknow India, after informed consent from the relatives and studied post-mortem degradation by incubation of the cardiac tissue at room temperature (20±2 OC) for different time periods (~7.30, 18.20, 30.30, 41.20, 41.40, 54.30, 65.20, and 88.40 Hours). The cases included were the subjects of burn without any prior history of disease who died in the hospital and their exact time of death was known. The analysis involved extraction of the protein, separation by denaturing gel electrophoresis (SDS-PAGE) and visualization by Western blot using cTnT specific monoclonal antibodies. The area of the bands within a lane was quantified by scanning and digitizing the image using Gel Doc. As time postmortem progresses the intact cTnT band degrades to fragments that are easily detected by the monoclonal antibodies. A decreasing trend in the level of cTnT (% of intact) was found as the PM hours increased. A significant difference was observed between <15 h and other PM hours (p<0.01). Significant difference in cTnT level (% of intact) was also observed between 16-25 h and 56-65 h & >75 h (p<0.01). Western blot data clearly showed the intact protein at 42 kDa, three major (28 kDa, 30kDa, 10kDa) fragments, three additional minor fragments (12 kDa, 14kDa, and 15 kDa) and formation of low molecular weight fragments. Overall, both PMI and cardiac tissue of burned corpse had a statistically significant effect where the greatest amount of protein breakdown was observed within the first 41.40 Hrs and after it intact protein slowly disappears. If the percent intact cTnT is calculated from the total area integrated within a Western blot lane, then the percent intact cTnT shows a pseudo-first order relationship when plotted against the time postmortem. A strong significant positive correlation was found between cTnT and PM hours (r=0.87, p=0.0001). The regression analysis showed a good variability explained (R2=0.768) The post-mortem Troponin-T fragmentation observed in this study reveals a sequential, time-dependent process with the potential for use as a predictor of PMI in cases of burning. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=burn" title="burn">burn</a>, <a href="https://publications.waset.org/abstracts/search?q=degradation" title=" degradation"> degradation</a>, <a href="https://publications.waset.org/abstracts/search?q=postmortem%20interval" title=" postmortem interval"> postmortem interval</a>, <a href="https://publications.waset.org/abstracts/search?q=troponin-T" title=" troponin-T"> troponin-T</a> </p> <a href="https://publications.waset.org/abstracts/30422/the-effect-of-elapsed-time-on-the-cardiac-troponin-t-degradation-and-its-utility-as-a-time-since-death-marker-in-cases-of-death-due-to-burn" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30422.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">449</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Vertebral Artery Dissection Complicating Pregnancy and Puerperium: Case Report and Review of the Literature</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=N.%20Reza%20Pour">N. Reza Pour</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Chuah"> S. Chuah</a>, <a href="https://publications.waset.org/abstracts/search?q=T.%20Vo"> T. Vo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Vertebral artery dissection (VAD) is a rare complication of pregnancy. It can occur spontaneously or following a traumatic event. The pathogenesis is unclear. Predisposing factors include chronic hypertension, Marfan’s syndrome, fibromuscular dysplasia, vasculitis and cystic medial necrosis. Physiological changes of pregnancy have also been proposed as potential mechanisms of injury to the vessel wall. The clinical presentation varies and it can present as a headache, neck pain, diplopia, transient ischaemic attack, or an ischemic stroke. Isolated cases of VAD in pregnancy and puerperium have been reported in the literature. One case was found to have posterior circulation stroke as a result of bilateral VAD and labour was induced at 37 weeks gestation for preeclampsia. Another patient at 38 weeks with severe neck pain that persisted after induction for elevated blood pressure and arteriography showed right VAD postpartum. A single case of lethal VAD in pregnancy with subsequent massive subarachnoid haemorrhage has been reported which was confirmed by the autopsy. Case Presentation: We report two cases of vertebral artery dissection in pregnancy. The first patient was a 32-year-old primigravida presented at the 38th week of pregnancy with the onset of early labour and blood pressure (BP) of 130/70 on arrival. After 2 hours, the patient developed a severe headache with blurry vision and BP was 238/120. Despite treatment with an intravenous antihypertensive, she had eclamptic fit. Magnesium solfate was started and Emergency Caesarean Section was performed under the general anaesthesia. On the second day after the operation, she developed left-sided neck pain. Magnetic Resonance Imaging (MRI) angiography confirmed a short segment left vertebral artery dissection at the level of C3. The patient was treated with aspirin and remained stable without any neurological deficit. The second patient was a 33-year-old primigavida who was admitted to the hospital at 36 weeks gestation with BP of 155/105, constant headache and visual disturbances. She was medicated with an oral antihypertensive agent. On day 4, she complained of right-sided neck pain. MRI angiogram revealed a short segment dissection of the right vertebral artery at the C2-3 level. Pregnancy was terminated on the same day with emergency Caesarean Section and anticoagulation was started subsequently. Post-operative recovery was complicated by rectus sheath haematoma requiring evacuation. She was discharged home on Aspirin without any neurological sequelae. Conclusion: Because of collateral circulation, unilateral vertebral artery dissections may go unrecognized and may be more common than suspected. The outcome for most patients is benign, reflecting the adequacy of the collateral circulation in young patients. Spontaneous VAD is usually treated with anticoagulation or antiplatelet therapy for a minimum of 3-6 months to prevent future ischaemic events, allowing the dissection to heal on its own. We had two cases of VAD in the context of hypertensive disorders of pregnancy with an acceptable outcome. A high level of vigilance is required particularly with preeclamptic patients presenting with head/neck pain to allow an early diagnosis. This is as we hypothesize, early and aggressive management of vertebral artery dissection may potentially prevent further complications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=eclampsia" title="eclampsia">eclampsia</a>, <a href="https://publications.waset.org/abstracts/search?q=preeclampsia" title=" preeclampsia"> preeclampsia</a>, <a href="https://publications.waset.org/abstracts/search?q=pregnancy" title=" pregnancy"> pregnancy</a>, <a href="https://publications.waset.org/abstracts/search?q=Vertebral%20Artery%20Dissection" title=" Vertebral Artery Dissection"> Vertebral Artery Dissection</a> </p> <a href="https://publications.waset.org/abstracts/29558/vertebral-artery-dissection-complicating-pregnancy-and-puerperium-case-report-and-review-of-the-literature" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/29558.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">279</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Meta-Analysis of Previously Unsolved Cases of Aviation Mishaps Employing Molecular Pathology</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Michael%20Josef%20Schwerer">Michael Josef Schwerer</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Analyzing any aircraft accident is mandatory based on the regulations of the International Civil Aviation Organization and the respective country’s criminal prosecution authorities. Legal medicine investigations are unavoidable when fatalities involve the flight crew or when doubts arise concerning the pilot’s aeromedical health status before the event. As a result of frequently tremendous blunt and sharp force trauma along with the impact of the aircraft to the ground, consecutive blast or fire exposition of the occupants or putrefaction of the dead bodies in cases of delayed recovery, relevant findings can be masked or destroyed and therefor being inaccessible in standard pathology practice comprising just forensic autopsy and histopathology. Such cases are of considerable risk of remaining unsolved without legal consequences for those responsible. Further, no lessons can be drawn from these scenarios to improve flight safety and prevent future mishaps. Aims and Methods: To learn from previously unsolved aircraft accidents, re-evaluations of the investigation files and modern molecular pathology studies were performed. Genetic testing involved predominantly PCR-based analysis of gene regulation, studying DNA promotor methylations, RNA transcription and posttranscriptional regulation. In addition, the presence or absence of infective agents, particularly DNA- and RNA-viruses, was studied. Technical adjustments of molecular genetic procedures when working with archived sample material were necessary. Standards for the proper interpretation of the respective findings had to be settled. Results and Discussion: Additional molecular genetic testing significantly contributes to the quality of forensic pathology assessment in aviation mishaps. Previously undetected cardiotropic viruses potentially explain e.g., a pilot’s sudden incapacitation resulting from cardiac failure or myocardial arrhythmia. In contrast, negative results for infective agents participate in ruling out concerns about an accident pilot’s fitness to fly and the aeromedical examiner’s precedent decision to issue him or her an aeromedical certificate. Care must be taken in the interpretation of genetic testing for pre-existing diseases such as hypertrophic cardiomyopathy or ischemic heart disease. Molecular markers such as mRNAs or miRNAs, which can establish these diagnoses in clinical patients, might be misleading in-flight crew members because of adaptive changes in their tissues resulting from repeated mild hypoxia during flight, for instance. Military pilots especially demonstrate significant physiological adjustments to their somatic burdens in flight, such as cardiocirculatory stress and air combat maneuvers. Their non-pathogenic alterations in gene regulation and expression will likely be misinterpreted for genuine disease by inexperienced investigators. Conclusions: The growing influence of molecular pathology on legal medicine practice has found its way into aircraft accident investigation. As appropriate quality standards for laboratory work and data interpretation are provided, forensic genetic testing supports the medico-legal analysis of aviation mishaps and potentially reduces the number of unsolved events in the future. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aviation%20medicine" title="aviation medicine">aviation medicine</a>, <a href="https://publications.waset.org/abstracts/search?q=aircraft%20accident%20investigation" title=" aircraft accident investigation"> aircraft accident investigation</a>, <a href="https://publications.waset.org/abstracts/search?q=forensic%20pathology" title=" forensic pathology"> forensic pathology</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20pathology" title=" molecular pathology"> molecular pathology</a> </p> <a href="https://publications.waset.org/abstracts/182910/meta-analysis-of-previously-unsolved-cases-of-aviation-mishaps-employing-molecular-pathology" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/182910.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">45</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Acute Severe Hyponatremia in Patient with Psychogenic Polydipsia, Learning Disability and Epilepsy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anisa%20Suraya%20Ab%20Razak">Anisa Suraya Ab Razak</a>, <a href="https://publications.waset.org/abstracts/search?q=Izza%20Hayat"> Izza Hayat</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: The diagnosis and management of severe hyponatremia in neuropsychiatric patients present a significant challenge to physicians. Several factors contribute, including diagnostic shadowing and attributing abnormal behavior to intellectual disability or psychiatric conditions. Hyponatraemia is the commonest electrolyte abnormality in the inpatient population, ranging from mild/asymptomatic, moderate to severe levels with life-threatening symptoms such as seizures, coma and death. There are several documented fatal case reports in the literature of severe hyponatremia secondary to psychogenic polydipsia, often diagnosed only in autopsy. This paper presents a case study of acute severe hyponatremia in a neuropsychiatric patient with early diagnosis and admission to intensive care. Case study: A 21-year old Caucasian male with known epilepsy and learning disability was admitted from residential living with generalized tonic-clonic self-terminating seizures after refusing medications for several weeks. Evidence of superficial head injury was detected on physical examination. His laboratory data demonstrated mild hyponatremia (125 mmol/L). Computed tomography imaging of his brain demonstrated no acute bleed or space-occupying lesion. He exhibited abnormal behavior - restlessness, drinking water from bathroom taps, inability to engage, paranoia, and hypersexuality. No collateral history was available to establish his baseline behavior. He was loaded with intravenous sodium valproate and leveritircaetam. Three hours later, he developed vomiting and a generalized tonic-clonic seizure lasting forty seconds. He remained drowsy for several hours and regained minimal recovery of consciousness. A repeat set of blood tests demonstrated profound hyponatremia (117 mmol/L). Outcomes: He was referred to intensive care for peripheral intravenous infusion of 2.7% sodium chloride solution with two-hourly laboratory monitoring of sodium concentration. Laboratory monitoring identified dangerously rapid correction of serum sodium concentration, and hypertonic saline was switched to a 5% dextrose solution to reduce the risk of acute large-volume fluid shifts from the cerebral intracellular compartment to the extracellular compartment. He underwent urethral catheterization and produced 8 liters of urine over 24 hours. Serum sodium concentration remained stable after 24 hours of correction fluids. His GCS recovered to baseline after 48 hours with improvement in behavior -he engaged with healthcare professionals, understood the importance of taking medications, admitted to illicit drug use and drinking massive amounts of water. He was transferred from high-dependency care to ward level and was initiated on multiple trials of anti-epileptics before achieving seizure-free days two weeks after resolution of acute hyponatremia. Conclusion: Psychogenic polydipsia is often found in young patients with intellectual disability or psychiatric disorders. Patients drink large volumes of water daily ranging from ten to forty liters, resulting in acute severe hyponatremia with mortality rates as high as 20%. Poor outcomes are due to challenges faced by physicians in making an early diagnosis and treating acute hyponatremia safely. A low index of suspicion of water intoxication is required in this population, including patients with known epilepsy. Monitoring urine output proved to be clinically effective in aiding diagnosis. Early referral and admission to intensive care should be considered for safe correction of sodium concentration while minimizing risk of fatal complications e.g. central pontine myelinolysis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=epilepsy" title="epilepsy">epilepsy</a>, <a href="https://publications.waset.org/abstracts/search?q=psychogenic%20polydipsia" title=" psychogenic polydipsia"> psychogenic polydipsia</a>, <a href="https://publications.waset.org/abstracts/search?q=seizure" title=" seizure"> seizure</a>, <a href="https://publications.waset.org/abstracts/search?q=severe%20hyponatremia" title=" severe hyponatremia"> severe hyponatremia</a> </p> <a href="https://publications.waset.org/abstracts/150049/acute-severe-hyponatremia-in-patient-with-psychogenic-polydipsia-learning-disability-and-epilepsy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/150049.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">122</span> </span> </div> </div> <ul class="pagination"> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=autopsy&page=1" rel="prev">&lsaquo;</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=autopsy&page=1">1</a></li> <li class="page-item active"><span class="page-link">2</span></li> <li class="page-item disabled"><span class="page-link">&rsaquo;</span></li> </ul> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a 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