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above-bg"> <nav role="navigation" aria-label="breadcrumb"> <ol class="nci-breadcrumb"> <li class="breadcrumb-item"> <a href="/"> <i class="fal fa-long-arrow-left"></i>Home </a> </li> <li class="breadcrumb-item"> <a href="/research"> <i class="fal fa-long-arrow-left"></i>RESEARCH at NCI </a> </li> </ol> </nav> <h1 class="title"> Biology </h1> </div> </div> </div> </div> </div> </div> </div> </header> <div class="site-content--main"> <div class="container-fluid site-content--main--wrap"> <div class="row"> <main class="main-content col order-first pl-0 pr-0" id="content" role="main"> <a id="main-content" tabindex="-1"></a> <div id="block-nci-content" class="block block-system block-system-main-block"> <div class="content"> <div class="views-element-container"> <section class="white-top-blue-bottom view view-taxonomy-term-searchable view-id-taxonomy_term_searchable view-display-id-page_terms js-view-dom-id-96f7635f0eff778bcd0e4da413b889689fa0d1ec314b1703aae46217aeb9714c"> <header class="view-header"> <div class="container"> <div class="row top-row"> <div class="col col-lg-10 offset-lg-1 col-xl-8 offset-xl-2 text-center"> <div class="taxonomy-term taxonomy-term--type-research-tags taxonomy-term--view-mode-full ds-1col clearfix"> <div class="field field--name-field-summary field--type-string-long field--label-hidden field__item"><h2 class="h3">Understanding the fundamentals of the natural systems around us is the key motivation for the biology research taking place at NCI. Researchers are conducting exciting, forward looking investigations into plant biology and agricultural methods, ecological systems, and the fundamentals of molecular biology.</h2> </div> </div> </div> </div> </div> </header> <div class="view-content-wrap "> <div class="view-content"> <div class="container"> <div class="row"> <div class="offset-xl-1 col-xl-10"> <div class="views-row"> <article class="node node--type-research-page node--view-mode-teaser-medium row"> <div class="col-3 col-sm-4 col-md-6 left"> <div class="field field-name-field-image"> <img loading="lazy" src="/sites/default/files/styles/medium_side_image/public/images/2024-06/Piezo%20Protein%20simulation.png?h=d1cb525d&itok=7v-bpi8g" width="445" height="320" alt="The MDFIC protein in pink binding with PIEZO, as seen through molecular dynamics simulations." typeof="foaf:Image" class="image-style-medium-side-image" /> </div> </div> <div class="col col-sm-8 col-md-6 col-lg-5 offset-lg-1 right"> <div class="group-body"> <div class="fields-inline tag"> <div class="field field-name-field-research-type"><a href="/research/case-studies" hreflang="en">Case Studies</a></div><div class="field field-name-node-post-date">18 Jun 2024</div> </div> <h2> <a href="/research/case-studies/getting-core-cell-biology" hreflang="en">Getting to the Core of Cell Biology</a> </h2> <div class="field field--name-field-research-tags field--type-entity-reference field--label-visually_hidden"> <div class="field__label visually-hidden">Research tags</div> <div class='field__items'> <div class="field__item"><a href="/research/tag-biology" hreflang="en">Biology</a></div> </div> </div> <div class="text-formatted field field-name-body"> Through high-performance computing and experimental collaborations, researchers are revealing some of the fundamental behaviours of human cells. PhD candidate YieChang Lin and Professor Ben Corry from <div class="more-link"><a href="/research/case-studies/getting-core-cell-biology" class="more-link" aria-label="Read more about Getting to the Core of Cell Biology" hreflang="en">Read more</a></div> </div> </div> </div> </article> </div> <div class="views-row"> <article class="node node--type-research-page node--view-mode-teaser-medium row"> <div class="col-3 col-sm-4 col-md-6 left"> <div class="field field-name-field-image"> <img loading="lazy" src="/sites/default/files/styles/medium_side_image/public/images/2024-05/national_cancer_institute.png?h=fae07d4e&itok=2xUsWEQl" width="445" height="320" alt="national_cancer_institute" typeof="foaf:Image" class="image-style-medium-side-image" /> </div> </div> <div class="col col-sm-8 col-md-6 col-lg-5 offset-lg-1 right"> <div class="group-body"> <div class="fields-inline tag"> <div class="field field-name-field-research-type"><a href="/research/case-studies" hreflang="en">Case Studies</a></div><div class="field field-name-node-post-date">09 May 2024</div> </div> <h2> <a href="/research/case-studies/deep-learning-genome-science" hreflang="en">Deep Learning for Genome Science</a> </h2> <div class="field field--name-field-research-tags field--type-entity-reference field--label-visually_hidden"> <div class="field__label visually-hidden">Research tags</div> <div class='field__items'> <div class="field__item"><a href="/research/tag-biology" hreflang="en">Biology</a></div> <div class="field__item"><a href="/research/tag-technology" hreflang="en">Technology</a></div> </div> </div> <div class="text-formatted field field-name-body"> Researchers are turning to Artificial Intelligence (AI) to understand the human genome better. By combining novel computing methods with extensive genomic datasets, they are developing new ways to <div class="more-link"><a href="/research/case-studies/deep-learning-genome-science" class="more-link" aria-label="Read more about Deep Learning for Genome Science" hreflang="en">Read more</a></div> </div> </div> </div> </article> </div> <div class="views-row"> <article class="node node--type-research-page node--view-mode-teaser-medium row"> <div class="col-3 col-sm-4 col-md-6 left"> <div class="field field-name-field-image"> <img loading="lazy" src="/sites/default/files/styles/medium_side_image/public/images/2023-02/Helping%20provide%20the%20best%20tools%20for%20children%27s%20cancer%20researchers%20-%20Cancer%20cells.jpg?h=a36e7c87&itok=gcK_cF9d" width="445" height="320" alt="A close-up view of a blue and green cancer cell, in front of a blue and green background. Additional cancer cells are out-of-focus. " typeof="foaf:Image" class="image-style-medium-side-image" /> </div> </div> <div class="col col-sm-8 col-md-6 col-lg-5 offset-lg-1 right"> <div class="group-body"> <div class="fields-inline tag"> <div class="field field-name-field-research-type"><a href="/research/research-highlights" hreflang="en">Research Highlights</a></div><div class="field field-name-node-post-date">07 Aug 2023</div> </div> <h2> <a href="/research/research-highlights/helping-provide-best-tools-childrens-cancer-researchers" hreflang="en">Helping provide the best tools for children's cancer researchers </a> </h2> <div class="field field--name-field-research-tags field--type-entity-reference field--label-visually_hidden"> <div class="field__label visually-hidden">Research tags</div> <div class='field__items'> <div class="field__item"><a href="/research/tag-biology" hreflang="en">Biology</a></div> <div class="field__item"><a href="/research/tag-health" hreflang="en">Health</a></div> </div> </div> <div class="text-formatted field field-name-body"> This research highlight was originally published in NCI's 2021-2022 Annual Report. World-class genomics infrastructure is needed to support Australian scientists and clinicians looking to develop <div class="more-link"><a href="/research/research-highlights/helping-provide-best-tools-childrens-cancer-researchers" class="more-link" aria-label="Read more about Helping provide the best tools for children&#039;s cancer researchers " hreflang="en">Read more</a></div> </div> </div> </div> </article> </div> <div class="views-row"> <article class="node node--type-research-page node--view-mode-teaser-medium row"> <div class="col-3 col-sm-4 col-md-6 left"> <div class="field field-name-field-image"> <img loading="lazy" src="/sites/default/files/styles/medium_side_image/public/images/2023-04/PREDICT-19%20logo1024_1.jpg?h=c12e0b96&itok=qIcJleQC" width="445" height="320" alt="Logo with different coloured letters and slogan underneath." typeof="foaf:Image" class="image-style-medium-side-image" /> </div> </div> <div class="col col-sm-8 col-md-6 col-lg-5 offset-lg-1 right"> <div class="group-body"> <div class="fields-inline tag"> <div class="field field-name-field-research-type"><a href="/research/research-highlights" hreflang="en">Research Highlights</a></div><div class="field field-name-node-post-date">14 Apr 2023</div> </div> <h2> <a href="/research/research-highlights/better-understanding-why-severe-covid-19-develops" hreflang="en">Better understanding why severe COVID-19 develops</a> </h2> <div class="field field--name-field-research-tags field--type-entity-reference field--label-visually_hidden"> <div class="field__label visually-hidden">Research tags</div> <div class='field__items'> <div class="field__item"><a href="/research/tag-biology" hreflang="en">Biology</a></div> <div class="field__item"><a href="/research/tag-health" hreflang="en">Health</a></div> </div> </div> <div class="text-formatted field field-name-body"> NCI supercomputing resources and bioinformatics expertise have improved our understanding of the differences between mild/moderate and severe COVID-19, helping to unravel how severe disease develops <div class="more-link"><a href="/research/research-highlights/better-understanding-why-severe-covid-19-develops" class="more-link" aria-label="Read more about Better understanding why severe COVID-19 develops" hreflang="en">Read more</a></div> </div> </div> </div> </article> </div> <div class="views-row"> <article class="node node--type-research-page node--view-mode-teaser-medium row"> <div class="col-3 col-sm-4 col-md-6 left"> <div class="field field-name-field-image"> <img loading="lazy" src="/sites/default/files/styles/medium_side_image/public/images/2023-03/Astronaut%20in%20space.jpg?h=2e091b46&itok=EaRVkmxb" width="445" height="320" alt="Astronaut in space with Earth in the background" typeof="foaf:Image" class="image-style-medium-side-image" /> </div> </div> <div class="col col-sm-8 col-md-6 col-lg-5 offset-lg-1 right"> <div class="group-body"> <div class="fields-inline tag"> <div class="field field-name-field-research-type"><a href="/research/research-highlights" hreflang="en">Research Highlights</a></div><div class="field field-name-node-post-date">23 Mar 2023</div> </div> <h2> <a href="/research/research-highlights/moon-mars-and-medical-lab-nci-supports-science-driving-better-human" hreflang="en">To the Moon, Mars and medical lab: NCI supports science driving better human health</a> </h2> <div class="field field--name-field-research-tags field--type-entity-reference field--label-visually_hidden"> <div class="field__label visually-hidden">Research tags</div> <div class='field__items'> <div class="field__item"><a href="/research/tag-astronomy" hreflang="en">Astronomy</a></div> <div class="field__item"><a href="/research/tag-biology" hreflang="en">Biology</a></div> <div class="field__item"><a href="/research/tag-engineering" hreflang="en">Engineering</a></div> <div class="field__item"><a href="/research/tag-health" hreflang="en">Health</a></div> <div class="field__item"><a href="/research/tag-physics" hreflang="en">Physics</a></div> </div> </div> <div class="text-formatted field field-name-body"> Radiation physicists from The University of Wollongong’s Centre For Medical Radiation Physics (CMRP) are using the power of NCI’s Gadi supercomputer to help keep astronauts safe and prepare for the <div class="more-link"><a href="/research/research-highlights/moon-mars-and-medical-lab-nci-supports-science-driving-better-human" class="more-link" aria-label="Read more about To the Moon, Mars and medical lab: NCI supports science driving better human health" hreflang="en">Read more</a></div> </div> </div> </div> </article> </div> <div class="views-row"> <article class="node node--type-research-page node--view-mode-teaser-medium row"> <div class="col-3 col-sm-4 col-md-6 left"> <div class="field field-name-field-image"> <img loading="lazy" src="/sites/default/files/styles/medium_side_image/public/images/2022-06/SuperbFairyWren_Timothee_Bonnet.jpg?h=e80dbf21&itok=n4DtU9lN" width="445" height="320" alt="A superb fairy wren sitting on a branch. It is a small, round bird with an upright tail and a vibrant, bright blue pattern on its head and neck." typeof="foaf:Image" class="image-style-medium-side-image" /> </div> </div> <div class="col col-sm-8 col-md-6 col-lg-5 offset-lg-1 right"> <div class="group-body"> <div class="fields-inline tag"> <div class="field field-name-field-research-type"><a href="/research/research-highlights" hreflang="en">Research Highlights</a></div><div class="field field-name-node-post-date">30 Jun 2022</div> </div> <h2> <a href="/research/research-highlights/understanding-speed-evolution" hreflang="en">Understanding the speed of evolution</a> </h2> <div class="field field--name-field-research-tags field--type-entity-reference field--label-visually_hidden"> <div class="field__label visually-hidden">Research tags</div> <div class='field__items'> <div class="field__item"><a href="/research/tag-biology" hreflang="en">Biology</a></div> </div> </div> <div class="text-formatted field field-name-body"> Evolution by natural selection is one of the central pillars of biology, explaining the amazing biodiversity observed on Earth and how species change over time. One of the aspects of evolutio n <div class="more-link"><a href="/research/research-highlights/understanding-speed-evolution" class="more-link" aria-label="Read more about Understanding the speed of evolution" hreflang="en">Read more</a></div> </div> </div> </div> </article> </div> <div class="views-row"> <article class="node node--type-research-page node--view-mode-teaser-medium row"> <div class="col-3 col-sm-4 col-md-6 left"> <div class="field field-name-field-image"> <img loading="lazy" src="/sites/default/files/styles/medium_side_image/public/images/2022-05/DNA%20Helix%20data.jpg?h=ed72fadd&itok=EnAKda1Y" width="445" height="320" alt="DNA Helix data" typeof="foaf:Image" class="image-style-medium-side-image" /> </div> </div> <div class="col col-sm-8 col-md-6 col-lg-5 offset-lg-1 right"> <div class="group-body"> <div class="fields-inline tag"> <div class="field field-name-field-research-type"><a href="/research/research-highlights" hreflang="en">Research Highlights</a></div><div class="field field-name-node-post-date">18 May 2022</div> </div> <h2> <a href="/research/research-highlights/finding-genetic-cause-lupus" hreflang="en">Finding the genetic cause of lupus</a> </h2> <div class="field field--name-field-research-tags field--type-entity-reference field--label-visually_hidden"> <div class="field__label visually-hidden">Research tags</div> <div class='field__items'> <div class="field__item"><a href="/research/tag-biology" hreflang="en">Biology</a></div> <div class="field__item"><a href="/research/tag-chemistry" hreflang="en">Chemistry</a></div> <div class="field__item"><a href="/research/tag-health" hreflang="en">Health</a></div> </div> </div> <div class="text-formatted field field-name-body"> A team of researchers have discovered a genetic variation that causes the debilitating disease Lupus. The supercomputing and data infrastructure at the National Computational Infrastructure (NCI) <div class="more-link"><a href="/research/research-highlights/finding-genetic-cause-lupus" class="more-link" aria-label="Read more about Finding the genetic cause of lupus" hreflang="en">Read more</a></div> </div> </div> </div> </article> </div> <div class="views-row"> <article class="node node--type-research-page node--view-mode-teaser-medium row"> <div class="col-3 col-sm-4 col-md-6 left"> <div class="field field-name-field-image"> <img loading="lazy" src="/sites/default/files/styles/medium_side_image/public/images/2022-01/DNA%20and%20keyboard.jpg?h=c6980913&itok=clB2V5GI" width="445" height="320" alt="An orange-hued image superimposing letters of a genome with a computer keyboard." typeof="foaf:Image" class="image-style-medium-side-image" /> </div> </div> <div class="col col-sm-8 col-md-6 col-lg-5 offset-lg-1 right"> <div class="group-body"> <div class="fields-inline tag"> <div class="field field-name-field-research-type"><a href="/research/research-highlights" hreflang="en">Research Highlights</a></div><div class="field field-name-node-post-date">21 Jan 2022</div> </div> <h2> <a href="/research/research-highlights/supporting-national-needs-high-throughput-computing" hreflang="en">Supporting national needs in high-throughput computing</a> </h2> <div class="field field--name-field-research-tags field--type-entity-reference field--label-visually_hidden"> <div class="field__label visually-hidden">Research tags</div> <div class='field__items'> <div class="field__item"><a href="/research/tag-biology" hreflang="en">Biology</a></div> <div class="field__item"><a href="/research/tag-health" hreflang="en">Health</a></div> <div class="field__item"><a href="/research/tag-technology" hreflang="en">Technology</a></div> </div> </div> <div class="text-formatted field field-name-body"> NCI supports Australian researchers across all of their computational and data needs, from High-Performance Computing (HPC) through to High-Performance Data (HPD) and High-Throughput Computing (HTC) <div class="more-link"><a href="/research/research-highlights/supporting-national-needs-high-throughput-computing" class="more-link" aria-label="Read more about Supporting national needs in high-throughput computing" hreflang="en">Read more</a></div> </div> </div> </div> </article> </div> <div class="views-row"> <article class="node node--type-research-page node--view-mode-teaser-medium row"> <div class="col-3 col-sm-4 col-md-6 left"> <div class="field field-name-field-image"> <img loading="lazy" src="/sites/default/files/styles/medium_side_image/public/images/2020-04/alcgthumb.jpg?h=38edde0a&itok=-Tfwg3Pn" width="445" height="320" alt="The letters A, L, C and G in blue on a translucent background showing computer imagery." typeof="foaf:Image" class="image-style-medium-side-image" /> </div> </div> <div class="col col-sm-8 col-md-6 col-lg-5 offset-lg-1 right"> <div class="group-body"> <div class="fields-inline tag"> <div class="field field-name-field-research-type"><a href="/research/research-highlights" hreflang="en">Research Highlights</a></div><div class="field field-name-node-post-date">27 Apr 2021</div> </div> <h2> <a href="/research/research-highlights/generating-great-australian-science-giant-research-grants" hreflang="en">Generating great Australian science with giant research grants</a> </h2> <div class="field field--name-field-research-tags field--type-entity-reference field--label-visually_hidden"> <div class="field__label visually-hidden">Research tags</div> <div class='field__items'> <div class="field__item"><a href="/research/tag-astronomy" hreflang="en">Astronomy</a></div> <div class="field__item"><a href="/research/tag-biology" hreflang="en">Biology</a></div> <div class="field__item"><a href="/research/tag-chemistry" hreflang="en">Chemistry</a></div> <div class="field__item"><a href="/research/tag-health" hreflang="en">Health</a></div> <div class="field__item"><a href="/research/tag-materials" hreflang="en">Materials</a></div> <div class="field__item"><a href="/research/tag-technology" hreflang="en">Technology</a></div> </div> </div> <div class="text-formatted field field-name-body"> NCI Australia is proud to support incredible Australian research through the 2021 Australasian Leadership Computing Grants (ALCG). The highly competitive Grants will allow researchers to work on some <div class="more-link"><a href="/research/research-highlights/generating-great-australian-science-giant-research-grants" class="more-link" aria-label="Read more about Generating great Australian science with giant research grants" hreflang="en">Read more</a></div> </div> </div> </div> </article> </div> <div class="views-row"> <article class="node node--type-research-page node--view-mode-teaser-medium row"> <div class="col-3 col-sm-4 col-md-6 left"> <div class="field field-name-field-image"> <img loading="lazy" src="/sites/default/files/styles/medium_side_image/public/images/2021-03/Journal%20of%20Phys%20Chem%20B%20Cover.jpeg?h=4fa50594&itok=vz7iCkN_" width="445" height="320" alt="The cover of the Journal of Physical Chemistry B featuring the interaction of proteins vital to the binding of COVID-19 to human cells." typeof="foaf:Image" class="image-style-medium-side-image" /> </div> </div> <div class="col col-sm-8 col-md-6 col-lg-5 offset-lg-1 right"> <div class="group-body"> <div class="fields-inline tag"> <div class="field field-name-field-research-type"><a href="/research/research-highlights" hreflang="en">Research Highlights</a></div><div class="field field-name-node-post-date">30 Mar 2021</div> </div> <h2> <a href="/research/research-highlights/modelling-a-potential-covid-19-cure" hreflang="en">Modelling a potential COVID-19 cure</a> </h2> <div class="field field--name-field-research-tags field--type-entity-reference field--label-visually_hidden"> <div class="field__label visually-hidden">Research tags</div> <div class='field__items'> <div class="field__item"><a href="/research/tag-biology" hreflang="en">Biology</a></div> <div class="field__item"><a href="/research/tag-health" hreflang="en">Health</a></div> </div> </div> <div class="text-formatted field field-name-body"> Once the COVID virus enters the body, it binds to and enters a cell, and starts producing copies of itself. Each new viral particle that is released can then bind to a new cell, and thus the infection <div class="more-link"><a href="/research/research-highlights/modelling-a-potential-covid-19-cure" class="more-link" aria-label="Read more about Modelling a potential COVID-19 cure" hreflang="en">Read more</a></div> </div> </div> </div> </article> </div> </div> </div> </div> </div> <aside class="container view-pagination"> <div class="row"> <nav aria-label="Page navigation"> <h4 id="pagination-heading" class="visually-hidden">Pagination</h4> <ul class="pagination js-pager__items"> <li class="page-item active "> <span class="page-link">1</span> </li> <li class="page-item next-mobile"> <a href="?page=1" title="" class="page-link">2</a> </li> <li class="page-item next-mobile"> <a href="?page=2" title="" class="page-link">3</a> </li> <li class="page-item next-mobile"> <a href="?page=3" title="" class="page-link">4</a> </li> <li class="page-item "> <a href="?page=4" title="" class="page-link">5</a> 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