High-Impact Research | GigaScience

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class="primaryContentHead"> <img class="collectionBanner" src="https://static.primary.prod.gcms.the-infra.com/static/site/gigascience/image/High+Impact+Collection+22/GigaScience+HI+Page+Banner.jpg?node=bfe068a9aef9b7834245&version=554618:1020dd7f7a5c48e5daf9" alt=""> <div class="objectTags"> <span class="formatLabel">Collection</span> </div> <h1>High-Impact Research from <em>GigaScience</em></h1> <div class="toolbar"> <ul> <li class="toolbarShare"> <div class="st-custom-button" data-network="sharethis" tabindex="0">Share</div> </li> </ul> </div> </div> <script type='text/javascript' src='https://platform-api.sharethis.com/js/sharethis.js#property=6481b8a5cc05f10013916a95&product=sop' async='async'></script> <script> document.addEventListener("readystatechange" ,function() { const compactButton = document.querySelector("div.st-custom-button"); if(compactButton) { const mutationObserver = new MutationObserver(entries => { if(document.body.classList.contains("st-body-no-scroll")) { compactButton.ariaExpanded = true; } else { compactButton.ariaExpanded = false; } }) mutationObserver.observe(document.body, { attributes: true }); } }) </script> <p>Explore a collection of the most read and most cited articles making an impact in <em>GigaScience</em> published within the past two years. This collection will be continuously updated with the journal's leading articles so be sure to revisit periodically to see what is being read and cited.</p> <p>Also discover the articles being discussed the most on digital media by <a data-link-id="28c1606c-2299-4333-99a6-81a3e12badaf" href="https://www.altmetric.com/explorer/report/b869630d-e8f9-4cd6-847a-f9bc5b449214">exploring this Altmetric report</a> pulling the most discussed articles from the past year.</p> <script type="text/javascript"> $(".expandableSection").hide(); $(".expandableSectionToggle").click(function() { var y = $(this).attr("trigger-for");$('#' + y).toggle(); }) </script> <div class="contentListing" id="537fb70ca22a22a77fb4"> <div class="widget widget-ArticleListNewAndPopular widget-instance-Home_MainContentB0gigascience_MostCited_4680"> <div id="newPopularList-Home_MainContentB0gigascience_MostCited_4680" class="fb"> <h3 class="widget-dynamic-title"> Most cited </h3> <div class="widget-layout widget-layout--vert "> <div class="widget-columns widget-col-1"> <div class="col"> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giac111" aria-hidden="true"></span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giac111/6874525?searchresult=1"> <div class="widget-dynamic-journal-title"> Open-source benchmarking of IBD segment detection methods for biobank-scale cohorts </div> </a> <div class="widget-dynamic-journal-authors"> Kecong Tang and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 11, 2022, giac111, <a href='https://doi.org/10.1093/gigascience/giac111'>https://doi.org/10.1093/gigascience/giac111</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/11/10.1093_gigascience_giac111/2/giac111fig1.jpeg?Expires=1735398694&Signature=QKHq0xe6j9WwcqNe76OWq4Y4k0VWBsxTSOsltes-TQUUuhqbeExRhU2exX98dhAcLDzWLp8rdPQUndygNOqrDsIeY~-WKQC39chXCp7iuYUMrs5YM6M~52o4q5G6Fgc8OORvXeMOwzxoyouy13mjbD3Ssc-P4MiBYobr3NKw-CyjqHbXSQGF40NomCjGye5cqpbdv~0wfd0dhZsDXr5yWHOhV8a8W6H8GUEU4tnhWx6tCuMbKcTyHuhtIlVGBLXRMCpJLw0Bomn-3hq8jW~KWo6W0wFfZk4gIDcnmezm34ZuLM30onDnx91lMF2CtFHQJGYPqWOc6iHnxc2bmDTJaQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> In the recent biobank era of genetics, the problem of identical-by-descent (IBD) segment detection received renewed interest, as IBD segments in large cohorts offer unprecedented opportunities in the study of population and genealogical history, as well as genetic association of long haplotypes. While a new generation of ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giad010" aria-hidden="true"></span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giad010/7059492?searchresult=1"> <div class="widget-dynamic-journal-title"> Contrast subgraphs allow comparing homogeneous and heterogeneous networks derived from omics data </div> </a> <div class="widget-dynamic-journal-authors"> Tommaso Lanciano and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 12, 2023, giad010, <a href='https://doi.org/10.1093/gigascience/giad010'>https://doi.org/10.1093/gigascience/giad010</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/12/10.1093_gigascience_giad010/2/giad010fig1.jpeg?Expires=1735398694&Signature=q7FxK5XKN4ATGCtJkSioVc7eBigm0txjThkPMDZz9knqrSu454AurafMiIuha9LXA0RJ0K9HRXzPWEMoAeCzIF0WhtZWmFXng7YSUHXHXzkJag-7-EW2L~50-ENI1Cixpx0lZQwZIwZfjQdo5dO0z9w5em92CSJP~MGQ68jE-u7G48Ss05IIn6mxGif0PdSZsqanb6UYgEDwXRqr0jykxqEZ~GzV1glI6vdqW5hKPGNylntKbx5WwdwQWW5kHZ8-pQO-Hiybe4oDKql4-Xz12TOs5wVvLDmsAYmTwByc7l9ndGkGypj7p5QEjq0xn~RSZ-slPJKgqkoEz67kDWhNLg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Biological networks are often used to describe the relationships between relevant entities, particularly genes and proteins, and are a powerful tool for functional genomics. Many important biological problems can be investigated by comparing biological networks between different conditions or networks obtained ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giad096" aria-hidden="true"></span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giad096/7432190?searchresult=1"> <div class="widget-dynamic-journal-title"> Variability analysis of LC-MS experimental factors and their impact on machine learning </div> </a> <div class="widget-dynamic-journal-authors"> Tobias Greisager Rehfeldt and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 12, 2023, giad096, <a href='https://doi.org/10.1093/gigascience/giad096'>https://doi.org/10.1093/gigascience/giad096</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/12/10.1093_gigascience_giad096/1/giad096fig1.jpeg?Expires=1735398694&Signature=WRQHwN8HoBIMmpLU9M-AygXHADgXDt8vOjtdv1H0IUWppINxnLMj4S4NR4XCA7B4iEMcNpLIKMXTVO-fBWquIqi-WOgcA5mHjuLupf6bROa0hCfKcsN6sM~zetFwAm8lAT6KBDoQNtLeFMYbhPwtAThw32yhMLah6Z8lUdVkMCfkvSX8ufBYNSNV1movbewLMnElgYlFgGWqP0O4Gh1HgO76i7qUby6RU9sbYdoJth466tfp0CUW7k0Yg0Ha5KY7aQa5qXsciOI31OjbDvuFjgYyjnCu9yrJ8w4CgOPMAyn9sRWKdViik1AsOMZDF0KVAgmOncTwEXcO1LLkjXuLpA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Machine learning (ML) technologies, especially deep learning (DL), have gained increasing attention in predictive mass spectrometry (MS) for enhancing the data-processing pipeline from raw data analysis to end-user predictions and rescoring. ML models need large-scale datasets for training and repurposing, which ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giad058" aria-hidden="true"></span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giad058/7243539?searchresult=1"> <div class="widget-dynamic-journal-title"> Lessons learned to boost a bioinformatics knowledge base reusability, the Bgee experience </div> </a> <div class="widget-dynamic-journal-authors"> Tarcisio Mendes de Farias and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 12, 2023, giad058, <a href='https://doi.org/10.1093/gigascience/giad058'>https://doi.org/10.1093/gigascience/giad058</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/12/10.1093_gigascience_giad058/1/giad058fig1.jpeg?Expires=1735398694&Signature=RVI4xyjy-fmMcaMFVcU5fA14e6q~JB9hDa5kr639mJStNBd3BBiP8a2lbS2JRNMPRxwh0ffSsr~yFuUr269Cx2OVmNCXb2aByBr-atliteyV6fVtLvuOl0AncDW45iQ9JEZUyMr6Fwa4BoJviyX4j7hqo47oJlz~cLxWrQD~-5siZjWOEuffiRFfZ8eTLEnOgKlybA7ncgE07QrjhKxM22Q98rQfDDN6hpgVSxsjCYTiixH8uaum3XL7IPLMtbIY2v9XhdFPjZiav7s306Pcz-pUO17oiK9MqrIb9AXZkItWSpzdewCwLioF~F8-Xfd9G3SnoXSRJwvFegevQ7yTtw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Enhancing interoperability of bioinformatics knowledge bases is a high-priority requirement to maximize data reusability and thus increase their utility such as the return on investment for biomedical research. A knowledge base may provide useful information for life scientists and other knowledge bases, but it ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giad087" aria-hidden="true"></span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giad087/7334271?searchresult=1"> <div class="widget-dynamic-journal-title"> epialleleR: an R/Bioconductor package for sensitive allele-specific methylation analysis in NGS data </div> </a> <div class="widget-dynamic-journal-authors"> Oleksii Nikolaienko and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 12, 2023, giad087, <a href='https://doi.org/10.1093/gigascience/giad087'>https://doi.org/10.1093/gigascience/giad087</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/12/10.1093_gigascience_giad087/1/giad087fig1.jpeg?Expires=1735398694&Signature=1ceKTHMZnEqbJhWtd2hbTu7yaHSFILGOogL9xc4y7Scx5hDy7OYa4YcHLXpxsV90c5IlErqCm56ameFpED7MX5b49dVfclZIz3P9NaPV6If~bk5gwPaO9EFI2-jcZ7sAcFFXbSCxtn3nl5jTcfcZqs6POh-tq4XMlMfpolG1~6XVLw1DotlrgGLzB2UyPOtIZ~HasF0ixIDY~A~e0oc0LzD0bzphVM-hnps1usFErjF8soWWJw-FP79w2Qv4LKvlffu1RdGawuTR25Cmj8rQy0wSU-t7tK6wbyJ4DXQMErmGLuRMaGhxAAVIRUYu85KMG4GKXKr7W0Lqacp13Pn6PA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Low-level mosaic epimutations within the BRCA1 gene promoter occur in 5–8% of healthy individuals and are associated with a significantly elevated risk of breast and ovarian cancer. Similar events may also affect other tumor suppressor genes, potentially being a significant contributor to cancer burden. While this opens a ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giad114" aria-hidden="true"></span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giad114/7528994?searchresult=1"> <div class="widget-dynamic-journal-title"> Open Data Governance at the Canadian Open Neuroscience Platform (CONP): From the Walled Garden to the Arboretum </div> </a> <div class="widget-dynamic-journal-authors"> Alexander Bernier and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 13, 2024, giad114, <a href='https://doi.org/10.1093/gigascience/giad114'>https://doi.org/10.1093/gigascience/giad114</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/13/10.1093_gigascience_giad114/10/giad114fig1.jpeg?Expires=1735398694&Signature=Zo~1D6FQAoXWDK5qLS0Af25cizUkTIRXvc4ST~UNEBXh8LHF8GrroJ0zeQ6NaiOY0kngNOYZrdReKcG3GW0Bix2HCnHSfrYZZpRmJUl1kPB3Ygvdf9PVYwM~TOpsI~YLes3mtg-hgpq4yhLWvLzut~9CE3JlxKadfrV7x30ttZ987KXX7excs22cb~8NkcNTNfXtc0kWVuUPW9AvhpOCDkCY79dIY~djJmnqjiVb3Za6f1dIeM8Jeg3UqbsON1Uv7OEzd0-U7osfdXedixin2WiZykRSTo5DKklkGsuwRE0LfzCgowF~d5aAYL~Fy5EXA5xixLWYTQLiYshIgdA9-g__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Scientific research communities pursue dual imperatives in implementing strategies to share their data. These communities attempt to maximize the accessibility of biomedical data for downstream research use, in furtherance of open science objectives. Simultaneously, such communities safeguard the interests of research ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giad007" aria-hidden="true"></span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giad007/7068386?searchresult=1"> <div class="widget-dynamic-journal-title"> High-throughput imaging of powdery mildew resistance of the winter wheat collection hosted at the German Federal ex situ Genebank for Agricultural and Horticultural Crops </div> </a> <div class="widget-dynamic-journal-authors"> Valentin Hinterberger and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 12, 2023, giad007, <a href='https://doi.org/10.1093/gigascience/giad007'>https://doi.org/10.1093/gigascience/giad007</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/12/10.1093_gigascience_giad007/1/giad007fig1.jpeg?Expires=1735398694&Signature=fIE6USwUh10wt8xVNvHWpzZZsm7aJcQQKmU4vFI2r1thdDxMCv8oOEgcTOBgRpAKAZQdlzMWodzYqq7y0qNdZllqbdEYeURGYgEx6gT2dHDoyRC4E-jISs5BoP76i9rvJgMKB~dgSzd1RinaJbLYLkaAggOTpCIvbX2rEk4ByuC9R6b-IUCtPI5tMjTrwvU5-~ijQsgo3aQpiHw~HfAoA0uH83DBoLqXaeLl1NHQeEmVqCbVyoRob5KWF2bhtZQivfeMa7GHqQxuIvXSMbJi8aQiCLhcjy2khBKK6axtQZvuq29jiP5fxvWkoVzIIWwAQbNEba5AOLBGVgZ-VsCBiw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Genebanks worldwide are transforming into biodigital resource centers, providing access not only to the plant material itself but also to its phenotypic and genotypic information. Adding information for relevant traits will help boost plant genetic resources' usage in breeding and research. Resistance traits are ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giad004" aria-hidden="true"></span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giad004/7080816?searchresult=1"> <div class="widget-dynamic-journal-title"> FAIR Island: real-world examples of place-based open science </div> </a> <div class="widget-dynamic-journal-authors"> Erin Robinson and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 12, 2023, giad004, <a href='https://doi.org/10.1093/gigascience/giad004'>https://doi.org/10.1093/gigascience/giad004</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/12/10.1093_gigascience_giad004/1/giad004fig1.jpeg?Expires=1735398694&Signature=siGxBfRnVKj-RC3ZLDqyt2TxID6AVOF-8mE82JyFSrntfuz4Ucd2ATHCEV3vZn3E0~RcS8L2BHH2TmMnmXrhZFmDemgjKMhJIEqZSqPqwliGHJYipRAwcHZU~C7~mR1eQb8vHBKgWAx1OVKGbtgBs0rpRzsGqxaquuHD50q40jWDbAvCUWVR8tWcsi4xiJ5TVvdf2K9XV~KvX~RKntdmWSZQKXhLls1Ts7akhGfACTcX66XkL8V4ULk~OmDvp1PBsL9dJBENj1pPQk8LlId8GslKMJ2ok3uoMDQHIH2LqYZFHIrLGWMgI~ZK2Yf8m05Q2qnin4S11Z~H0ezNFFS4kw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> The relationship between people, place, and data presents challenges and opportunities for science and society. While there has been general enthusiasm for and work toward Findable, Accessible, Interoperable, and Reusable (FAIR) data for open science, only more recently have these data-centric principles been extended into ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giad031" aria-hidden="true"></span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giad031/7150394?searchresult=1"> <div class="widget-dynamic-journal-title"> A workflow reproducibility scale for automatic validation of biological interpretation results </div> </a> <div class="widget-dynamic-journal-authors"> Hirotaka Suetake and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 12, 2023, giad031, <a href='https://doi.org/10.1093/gigascience/giad031'>https://doi.org/10.1093/gigascience/giad031</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/12/10.1093_gigascience_giad031/1/giad031fig1.jpeg?Expires=1735398694&Signature=qaZ-kZS4ybUwzzXpAS1pYx4gHxWRGX1N0~CWFdBqVTFM-p7v-sAqVZkCOLz8J9rk6sxKyvKNE-gU1YskI-vbX1SVO-C4UhWcR~ZU2nsqUeeUl6I6CzZPpZqpgU-4M7F8Yx0DK9tCyMLI4jhKJpZjouEgTkHU18DQx5wiExIc0dfMiEcOE-FH1v4lzt9tnGv0I5yRsFizVA7TDjYXU1GBhXeni1oYZ0RDvnPSAm6v1vNxTtN8rGgkQgEkjgYaaXE0P5Gr1dHq3-toEwGIht8fPguDAlH2fFQO7g0vYJ6-i4hNs5jo8PmkIcAKv~IrZ1044PY4UtLbTRmKXY9-pD-AUA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Reproducibility of data analysis workflow is a key issue in the field of bioinformatics. Recent computing technologies, such as virtualization, have made it possible to reproduce workflow execution with ease. However, the reproducibility of results is not well discussed; that is, there is no standard way to ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giad060" aria-hidden="true"></span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giad060/7232826?searchresult=1"> <div class="widget-dynamic-journal-title"> Health record hiccups—5,526 real-world time series with change points labelled by crowdsourced visual inspection </div> </a> <div class="widget-dynamic-journal-authors"> T Phuong Quan and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 12, 2023, giad060, <a href='https://doi.org/10.1093/gigascience/giad060'>https://doi.org/10.1093/gigascience/giad060</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/12/10.1093_gigascience_giad060/1/giad060fig1.jpeg?Expires=1735398694&Signature=jwE3VMxxqpFDcZb1FkgzGgbQCrKjjCSQJqJN21rJj5nSlkqWp7uCQcIy1J3zq6Fv1rfucHT3yXFb2CldTL5w3B~cjuX642R1~3A1quwFePCFDz6fUhZy7fIJ65dGT0chKMmhTSKDRjFkicHjOI8eqBJjSEmQXCze9b2SKmiEdrg7tBQRTvAyzCoy8QxvqAojf4NW7JMoAlZv7b06XcuId95ikE55NqiKqDir61~A3E0~PJt6L-bjRNbVRPTn03iUh5LEz-JKVunwMZDbINoIi9tUaQu7p2vSetjr1cU-ANFPX~IuMIXnO9-JbeWMu2OyHLqTdYDSsn-YXxzB4ye5cQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Large routinely collected data such as electronic health records (EHRs) are increasingly used in research, but the statistical methods and processes used to check such data for temporal data quality issues have not moved beyond manual, ad hoc production and visual inspection of graphs. With the prospect of EHR ... </div> </div> </div> </div> </div> </div></div> </div> </div> <div class="contentListing" id="575ccdbb09157039b108"> <div class="widget widget-ArticleListNewAndPopular widget-instance-Home_MainContentB0gigascience_MostRead_4680"> <div id="newPopularList-Home_MainContentB0gigascience_MostRead_4680" class="fb"> <h3 class="widget-dynamic-title"> Most read </h3> <div class="widget-layout widget-layout--vert "> <div class="widget-columns widget-col-1"> <div class="col"> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giad047" aria-hidden="true"></span> <span class="type-name-article-flag">Research Article</span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giad047/7232825?searchresult=1"> <div class="widget-dynamic-journal-title"> Hetnet connectivity search provides rapid insights into how biomedical entities are related </div> </a> <div class="widget-dynamic-journal-authors"> Daniel S Himmelstein and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 12, 2023, giad047, <a href='https://doi.org/10.1093/gigascience/giad047'>https://doi.org/10.1093/gigascience/giad047</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/12/10.1093_gigascience_giad047/7/giad047fig1.jpeg?Expires=1735398695&Signature=qRO5R95iuuwQCYgSW0v0ci8Ls7FwWsxibs-~ziPKDVz5zd1ZC-2XvsaRcmOLSTC2gWt3TrLCi-lSaPu~KEdr3mcClhsun3gbxCU8~PFByWdR03~Xr6mvsNVLiT5pk~9BLg6FC3v3NfHuv1CUF7CiaisOpOE3I1JbQ2qzqhzsIC9e6NGy7OATRVptVc8KyXSYw3Sm222LDGnTW8YPEAIWw9vjr7UfzrCDxVMB~oI35lZ5~XH8JHolveyCQ1qY~Z6AQUf9VxqZNQJ2lXMAynVKr-HO3~VsXlxTqxOnisn0UjK1Dp6kjuAp4f5sIkE5uiWBzEsbGHvcD0AjkzYSk7ZweA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Hetnets, short for “heterogeneous networks,” contain multiple node and relationship types and offer a way to encode biomedical knowledge. One such example, Hetionet, connects 11 types of nodes—including genes, diseases, drugs, pathways, and anatomical structures—with over 2 million edges of 24 types. Previous ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giae073" aria-hidden="true"></span> <span class="type-name-article-flag">Research Article</span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giae073/7845193?searchresult=1"> <div class="widget-dynamic-journal-title"> Discovering genotype–phenotype relationships with machine learning and the Visual Physiology Opsin Database (<em>VPOD</em>) </div> </a> <div class="widget-dynamic-journal-authors"> Seth A Frazer and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 13, 2024, giae073, <a href='https://doi.org/10.1093/gigascience/giae073'>https://doi.org/10.1093/gigascience/giae073</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/13/10.1093_gigascience_giae073/1/giae073fig1.jpeg?Expires=1735398695&Signature=yBdZ6F6Nho6HJUHOEkqQ5-fBeNwr1uiUzzyTv2Oq0qthqrCViPwq8YF~-bOcx3w5GrA6MFL7bTKqJuK2bXC6EyjN200hk5Nwh-lBGsnWyjWTwOy444zFKS-9TkkHbOW2P-g4VRj6i6hwC0VMZK0Qd-IpMnaIq-pDmP5zIfCgkdD5oKtWApjt3Ze2cMPXn1J~-6fr1NR3k7EuLkXHyEo6aqwRpKK8ECPYnrBNzRg9UKcc6AuSueVKRx3uoz6EbWLIaQi2M8Cd6iVa2Mr5Xanw55~xuSUK5odHYWOhuRi0utD8ik~DBsPFgs0RW~WAJQbBJrYV6l3pNInk8806-7gR7Q__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Predicting phenotypes from genetic variation is foundational for fields as diverse as bioengineering and global change biology, highlighting the importance of efficient methods to predict gene functions. Linking genetic changes to phenotypic changes has been a goal of decades of experimental work, especially for ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giae081" aria-hidden="true"></span> <span class="type-name-article-flag">Research Article</span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giae081/7824698?searchresult=1"> <div class="widget-dynamic-journal-title"> Genomic exploration of the endangered oriental stork, <em>Ciconia boyciana</em>, sheds light on migration adaptation and future conservation </div> </a> <div class="widget-dynamic-journal-authors"> Shangchen Yang and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 13, 2024, giae081, <a href='https://doi.org/10.1093/gigascience/giae081'>https://doi.org/10.1093/gigascience/giae081</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/13/10.1093_gigascience_giae081/3/giae081fig1.jpeg?Expires=1735398695&Signature=1TDiiUEGp8PUUubFqJUf9c61AAwLjzopKUHqQgqfBDRmErhYdb0TtP774BEUgrj5aCoG5uE804owoyJLeS03IEkustrcNNRxc00XAFZ~MDYDqAJSQ9-Ifyv7~H0A-A-H9F9BIbwbUXMWoWiWomVJ1bYe5cZHhR4FsKziAmtqcZqTRmBkEKAAjLYL6BtX72kXNFIlIbQuEae2EOVqvfsft-Qgk10SQjcIUS-ILDnqqO6fV2GuVhiU9zT3ocUc5hopBIONY~wr-ljeuxEPXadudDT945IC3ZITpKNmRT2WVc40g1J8uB8yXBGl9L4vgmecdZgsFW7EboTolD9pqUKKdw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background The oriental stork, Ciconia boyciana , is an endangered migratory bird listed on the International Union for Conservation of Nature’s Red List. The bird population has experienced a rapid decline in the past decades, with nest locations and stop-over sites largely degraded due to human–bird conflicts. ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giae049" aria-hidden="true"></span> <span class="type-name-article-flag">Research Article</span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giae049/7727520?searchresult=1"> <div class="widget-dynamic-journal-title"> CAT: a computational anatomy toolbox for the analysis of structural MRI data </div> </a> <div class="widget-dynamic-journal-authors"> Christian Gaser and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 13, 2024, giae049, <a href='https://doi.org/10.1093/gigascience/giae049'>https://doi.org/10.1093/gigascience/giae049</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/13/10.1093_gigascience_giae049/3/giae049fig1.jpeg?Expires=1735398695&Signature=R-88mzgrSIuprjvCph9ZrXfP-PHD16ep7WuZKy7Nlo-8d7lsZINwgSVgspUmFT800FyitBBLe5RyMzDMGF~UIvXq7DOVRymq2ck6U8-wr8pAABZAa0HLpIb7gG6UCkKpQ5Dxo8m2r-8u4MXo5yjZ6KeXKj-O5Pk~6tCzbAWVDV3ykpmtdaBjICEPSFddM0aA5IltAii4cJHKz3xe2XcoFMKhQhsyfWknb2UA6oIp3TmiLGQD-eD91u93Zb7jreDC40-VDZECtv9PZgxXP-~6hyG5oOoytBWfjrgwu9Vzz2UOiCm5g3B3U51UTcDEZrRGup68MQF2SnBWJUX88szMTQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> A large range of sophisticated brain image analysis tools have been developed by the neuroscience community, greatly advancing the field of human brain mapping. Here we introduce the Computational Anatomy Toolbox (CAT)—a powerful suite of tools for brain morphometric analyses with an intuitive graphical user interface but ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giae076" aria-hidden="true"></span> <span class="type-name-article-flag">Research Article</span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giae076/7845194?searchresult=1"> <div class="widget-dynamic-journal-title"> vEMstitch: an algorithm for fully automatic image stitching of volume electron microscopy </div> </a> <div class="widget-dynamic-journal-authors"> Bintao He and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 13, 2024, giae076, <a href='https://doi.org/10.1093/gigascience/giae076'>https://doi.org/10.1093/gigascience/giae076</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/13/10.1093_gigascience_giae076/1/giae076fig1.jpeg?Expires=1735398695&Signature=cJ9s5deLshdz5UJ8kEARS0bK2GVs1Nyv6XJiW3J-BnQrd9aJEZ4XevL1c2sz7Y00uaUrNIakNXhv3D9ddm95xLs9Yn7jqpFcbg0irw3OlOwd4mmuYIKmTSRmqCG0D9Ai87KPlUrAJZTYxk0LiIqvD1QJYKQmYVNAoGKrou56CBQWrzS8jjYoHLM0qY-ndJwWbOxqjtymDBPyZOMKagB8jORZggmoPLFg7Va-Lb9rO4VdS4L5OBfWGxh3EvZYVBK~GRQVpu6hOnVq0CNrddVmViPGQviDShh42lUB2Fr0gzjnmD9nqeGvp7y150~BTgTyhNTM3iGcWpI4GNz0D1NF8w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background As software and hardware have developed, so has the scale of research into volume electron microscopy (vEM), leading to ever-increasing resolution. Usually, data collection is followed by image stitching: the same area is subjected to high-resolution imaging with a certain overlap, and then the images are ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giae080" aria-hidden="true"></span> <span class="type-name-article-flag">Research Article</span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giae080/7824699?searchresult=1"> <div class="widget-dynamic-journal-title"> Protein–protein and protein–nucleic acid binding site prediction via interpretable hierarchical geometric deep learning </div> </a> <div class="widget-dynamic-journal-authors"> Shizhuo Zhang and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 13, 2024, giae080, <a href='https://doi.org/10.1093/gigascience/giae080'>https://doi.org/10.1093/gigascience/giae080</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/13/10.1093_gigascience_giae080/4/giae080fig1.jpeg?Expires=1735398695&Signature=zFRZwJKY-OU9vGRSjj7WIJ2qG3Ahpy85DNin~NQ2~dHjqhbyQTw0AYSj~hufL8kETKOLOjefT--NhT4LVGE1UdY5mShowbp392gpirw-DmTSv-qOjvVge-6f6YqHX3eNtSOdTXusYUO9VukyJuz9Ux7JkzUmD1wMIL5JjNB8d4AMpP9rnFhWu7tzw42-MYvTAGJgan9rMAChLXWUzCKUogHVKYp-PbyuKNw6gQGlc~JzhKRJJQBy8Hpocl7bgTGayNn3H4B2IN1e~5jTYTilAkg6dvcgRrfMHrm9TMWKCk5RrcQO-yFxxD-jG5r-D-VcoAeLXFjk1P2bkxdcqP~BEQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Identification of protein–protein and protein–nucleic acid binding sites provides insights into biological processes related to protein functions and technical guidance for disease diagnosis and drug design. However, accurate predictions by computational approaches remain highly challenging due to the limited knowledge of ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giae078" aria-hidden="true"></span> <span class="type-name-article-flag">Research Article</span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giae078/7841112?searchresult=1"> <div class="widget-dynamic-journal-title"> StereoSiTE: a framework to spatially and quantitatively profile the cellular neighborhood organized iTME </div> </a> <div class="widget-dynamic-journal-authors"> Xing Liu and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 13, 2024, giae078, <a href='https://doi.org/10.1093/gigascience/giae078'>https://doi.org/10.1093/gigascience/giae078</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/13/10.1093_gigascience_giae078/1/giae078fig1.jpeg?Expires=1735398695&Signature=tr2zSFyTov-6ufnsz1DwZzeRT79KSCuvZr6HlhiISNOTMHXfOya6AbXq002ECajVrk1O-LZ7iKlua1KXW6J6QM7gL4HHYI-738U6irBYGaQqEtkPcT2EmN95DpKemrT0Eb~6PoL~U2QzlwfKJilhaxTXXeOEzLHL78EnhNneUDHhaLw~Rtyob3puHO~s~JtS8cIvuj5rdqj-WJp3Gzt2368efKnARLiyWT97m1Mm6h006fV03ztKmpqNyO3p7-LSPAAXyhpwPYV7UagtzXgu4iaeKetj2D-GJcgVmqGJaQ-ckkqCiCYK61aQpqN8-KxYq-sKMlToE6gX7EIPlaQlcw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Spatial transcriptome (ST) technologies are emerging as powerful tools for studying tumor biology. However, existing tools for analyzing ST data are limited, as they mainly rely on algorithms developed for single-cell RNA sequencing data and do not fully utilize the spatial information. While some algorithms ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giae061" aria-hidden="true"></span> <span class="type-name-article-flag">Research Article</span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giae061/7824697?searchresult=1"> <div class="widget-dynamic-journal-title"> DNA methylation analysis to differentiate reference, breed, and parent-of-origin effects in the bovine pangenome era </div> </a> <div class="widget-dynamic-journal-authors"> Callum MacPhillamy and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 13, 2024, giae061, <a href='https://doi.org/10.1093/gigascience/giae061'>https://doi.org/10.1093/gigascience/giae061</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/13/10.1093_gigascience_giae061/3/giae061fig1.jpeg?Expires=1735398695&Signature=VnORUcpc7pnAc8FDTDQmorrPqpPLywUT-zOflYAPO4Ej1GLZboNoefxmZQcOollX6XAAuB1CrxhbQEhu8-GWN~kZqnn0zXebWHSHVdICL-FPiqh-f4r8lIOAAOpXTltbefbaQwsDK3SReJ-N9svJb~N4p9sstlml8O6bbAHeRCsuvxfQOBgc-6S~i6Bz71UcJ7wJ9SIrBTbWj65zxD1xm25bJ0RnvRSWmQobzCYL6tAelgFLyZZg1lktMEKsXaU6ZRX-dEnLwvqPHtB1pVex8SAh5niDe1fBoVPxYaN0BlsOMOJlpw4TbGC7U5vWEyADn~Qf8Ph62pggisEuO3yhvw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Most DNA methylation studies have used a single reference genome with little attention paid to the bias introduced due to the reference chosen. Reference genome artifacts and genetic variation, including single nucleotide polymorphisms (SNPs) and structural variants (SVs), can lead to differences in methylation ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giae075" aria-hidden="true"></span> <span class="type-name-article-flag">Brief Report</span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giae075/7817745?searchresult=1"> <div class="widget-dynamic-journal-title"> High-quality assembly of the T2T genome for <em>Isodon rubescens</em> f. <em>lushanensis</em> reveals genomic structure variations between 2 typical forms of <em>Isodon rubescens</em> </div> </a> <div class="widget-dynamic-journal-authors"> Hao Yang and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 13, 2024, giae075, <a href='https://doi.org/10.1093/gigascience/giae075'>https://doi.org/10.1093/gigascience/giae075</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/13/10.1093_gigascience_giae075/3/giae075fig1.jpeg?Expires=1735398695&Signature=ltUEWU7KGN~0-~7xWLSczNwtUmFZodF0YXooQDF~DZJnAfVcAxi6dl5NFj9mS0GZTptp0qcX1hhxDrqwCj8oXgyKY1yvoGSmI8F4F3Cry~Z71xBiWl7BKYbvkmRGJlwurGSuB75~JL~ZpITTaF48UAxNij-PwByyX4V7~8qisK0Vmm9Ek0YNoZFIbPW2cZqX9seqsX8SXy~TkYyLZagIDYw8qsvNP1OddQ2Q~oilBAjhLvr2yBslMKVdwHieqoqc0bX1hvsWcK26mnk8xdIIJZD7OzpkvHPYCMI2t3VXhSs08Rzwu-ZQvzdXAOBWtXf2CFI8aquXur-2XRWs-D~z1A__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Rabdosiae rubescentis herba ( Isodon rubescens ) is widely used as a folk medicine to treat esophageal cancer and sore throat in China. Its germplasm resources are abundant in China, with I. rubescens (Hemsl.) Hara and I. rubescens f. lushanensis as 2 typical forms. I. rubescens (Hemsl.) Hara is featured by ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1093/gigascience/giae074" aria-hidden="true"></span> <span class="type-name-article-flag">Research Article</span> <a class="journal-link" href="/gigascience/article/doi/10.1093/gigascience/giae074/7774894?searchresult=1"> <div class="widget-dynamic-journal-title"> PhageGE: an interactive web platform for exploratory analysis and visualization of bacteriophage genomes </div> </a> <div class="widget-dynamic-journal-authors"> Jinxin Zhao and others </div> <div class="widget-dynamic-journal-citation journal-citation citation-margin"> <em>GigaScience</em>, Volume 13, 2024, giae074, <a href='https://doi.org/10.1093/gigascience/giae074'>https://doi.org/10.1093/gigascience/giae074</a> </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/gigascience/13/10.1093_gigascience_giae074/2/giae074fig1.jpeg?Expires=1735398695&Signature=Jb-aNXr-RLcNZbUVMtM5kKn0DZq-ipWMhBrrWeXMqZegn4syETO9XDi~vmnjyRisY71pBVJVv~z2FbPXXTEFyN1TeIuQ~LhjlN~Ki-1aHqYMxM4-xeWgROdADTGwJtb5YrF~2wNLOeSMbtQzAHncC2sJVrH2DlRtvLrEluz5CwFfd1BZ5PK3lYRkY1dzidKhMackW3UCwuvFm-zwRKNSN8mvo8xVOwrs3sB3lAq6D64y-mWhDmxWs3aBsXc1HJZDDwPSPNLoYImkV4NOUq2VJJAKyffJGqrArWjO6ClTWhnuBrj942gykCEm3PhN3YrwfU-2eXJoYIEUOCXBH0l1xg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Antimicrobial resistance is a serious threat to global health. Due to the stagnant antibiotic discovery pipeline, bacteriophages (phages) have been proposed as an alternative therapy for the treatment of infections caused by multidrug-resistant pathogens. Genomic features play an important role in phage ... </div> </div> </div> </div> </div> </div></div> </div> </div> </div></div><div class="right"> <div class="ad"> <div class="widget widget-AdBlockDynamic widget-instance-SecondaryTemplate_RightRailB0SelfServeTopSidebar"> <div class="js-adBlock-parent-wrap"> <div class="adBlockMainBodyTop-wrap js-adBlockMainBodyTop hide"> <div id="adBlockMainBodyTop" class="js-adblock" style=" " data-lazy-load-margin="150"> <script> googletag.cmd.push(function () { googletag.display('adBlockMainBodyTop'); }); </script> </div> <div class="advertisement-text js-adblock-advertisement-text hide">Advertisement</div> </div> </div> </div> </div> <div class="dynamicList articleListNewAndPopularTabbed"> <div class="widget widget-ArticleListNewAndPopular widget-instance-SecondaryTemplate_RightRailB0Secondary_RightRail_ArticleNewPopularCombined"> <ul class="articleListNewAndPopularCombinedView"> <li> <h3> <a href="javascript:;" class="articleListNewAndPopular-mode 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