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biopsy</title> <meta name="description" content="Search results for: core biopsy"> <meta name="keywords" content="core biopsy"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler 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id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="core biopsy"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 2129</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: core biopsy</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2129</span> Diagnostic Accuracy Of Core Biopsy In Patients Presenting With Axillary Lymphadenopathy And Suspected Non-Breast Malignancy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Monisha%20Edirisooriya">Monisha Edirisooriya</a>, <a href="https://publications.waset.org/abstracts/search?q=Wilma%20Jack"> Wilma Jack</a>, <a href="https://publications.waset.org/abstracts/search?q=Dominique%20Twelves">Dominique Twelves</a>, <a href="https://publications.waset.org/abstracts/search?q=Jennifer%20Royds"> Jennifer Royds</a>, <a href="https://publications.waset.org/abstracts/search?q=Fiona%20Scott"> Fiona Scott</a>, <a href="https://publications.waset.org/abstracts/search?q=Nicola%20Mason"> Nicola Mason</a>, <a href="https://publications.waset.org/abstracts/search?q=Arran%20Turnbull"> Arran Turnbull</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Michael%20Dixon"> J. Michael Dixon</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Excision biopsy has been the investigation of choice for patients presenting with pathological axillary lymphadenopathy without a breast abnormality. Core biopsy of nodes can provide sufficient tissue for diagnosis and has advantages in terms of morbidity and speed of diagnosis. This study evaluates the diagnostic accuracy of core biopsy in patients presenting with axillary lymphadenopathy. Methods: Between 2009 and 2019, 165 patients referred to the Edinburgh Breast Unit had a total of 179 axillary lymph node core biopsies. Results: 152 (92%) of the 165 initial core biopsies were deemed to contain adequate nodal tissue. Core biopsy correctly established malignancy in 75 of the 78 patients with haematological malignancy (96%) and in all 28 patients with metastatic carcinoma (100%) and correctly diagnosed benign changes in 49 of 57 (86%) patients with benign conditions. There were no false positives and no false negatives. In 67 (85.9%) of the 78 patients with hematological malignancy, there was sufficient material in the first core biopsy to allow the pathologist to make an actionable diagnosis and not ask for more tissue sampling prior to treatment. There were no complications of core biopsy. On follow up, none of the patients with benign cores has been shown to have malignancy in the axilla and none with lymphoma had their initial disease incorrectly classified. Conclusions: This study shows that core biopsy is now the investigation of choice for patients presenting with axillary lymphadenopathy even in those suspected as having lymphoma. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=core%20biopsy" title="core biopsy">core biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=excision%20biopsy" title=" excision biopsy"> excision biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=axillary%20lymphadenopathy" title=" axillary lymphadenopathy"> axillary lymphadenopathy</a>, <a href="https://publications.waset.org/abstracts/search?q=non-breast%20malignancy" title=" non-breast malignancy"> non-breast malignancy</a> </p> <a href="https://publications.waset.org/abstracts/141187/diagnostic-accuracy-of-core-biopsy-in-patients-presenting-with-axillary-lymphadenopathy-and-suspected-non-breast-malignancy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/141187.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">241</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2128</span> An Audit of Local Guidance Compliance For Stereotactic Core Biopsy For DCIS In The Breast Screening Programme</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aisling%20Eves">Aisling Eves</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrew%20Pieri"> Andrew Pieri</a>, <a href="https://publications.waset.org/abstracts/search?q=Ross%20McLean"> Ross McLean</a>, <a href="https://publications.waset.org/abstracts/search?q=Nerys%20Forester"> Nerys Forester</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The breast unit local guideline recommends that 12 cores should be used in a stereotactic-guided biopsy to diagnose DCIS. Twelve cores are regarded to provide good diagnostic value without removing more breast tissue than necessary. This study aimed to determine compliance with guidelines and investigated how the number of cores impacted upon the re-excision rate and size discrepancies. Methods: This single-centre retrospective cohort study of 72 consecutive breast screened patients with <15mm DCIS on radiological report underwent stereotactic-guided core biopsy and subsequent surgical excision. Clinical, radiological, and histological data were collected over 5 years, and ASCO guidelines for margin involvement of <2mm was used to guide the need for re-excision. Results: Forty-six (63.9%) patients had <12 cores taken, and 26 (36.1%) patients had ≥12 cores taken. Only six (8.3%) patients had 12 cores taken in their stereotactic biopsy. Incomplete surgical excision was seen in 17 patients overall (23.6%), and of these patients, twelve (70.6%) had fewer than 12 cores taken (p=0.55 for the difference between groups). Mammogram and biopsy underestimated the size of the DCIS in this subgroup by a median of 15mm (range: 6-135mm). Re-excision was required in 9 patients (12.5%), and five patients (6.9%) were found to have invasive ductal carcinoma on excision (80% had <12 cores, p=0.43). Discussion: There is poor compliance with the breast unit local guidelines and higher rates of re-excision in patients who did not have ≥12 cores taken. Taking ≥12 cores resulted in fewer missed invasive cancers lower incomplete excision and re-excision rates. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=stereotactic%20core%20biopsy" title="stereotactic core biopsy">stereotactic core biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=DCIS" title=" DCIS"> DCIS</a>, <a href="https://publications.waset.org/abstracts/search?q=breast%20screening" title=" breast screening"> breast screening</a>, <a href="https://publications.waset.org/abstracts/search?q=Re-excision%20rates" title=" Re-excision rates"> Re-excision rates</a>, <a href="https://publications.waset.org/abstracts/search?q=core%20biopsy" title=" core biopsy"> core biopsy</a> </p> <a href="https://publications.waset.org/abstracts/146029/an-audit-of-local-guidance-compliance-for-stereotactic-core-biopsy-for-dcis-in-the-breast-screening-programme" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/146029.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">128</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2127</span> Histological Grade Concordance between Core Needle Biopsy and Corresponding Surgical Specimen in Breast Carcinoma</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=J.%20Szpor">J. Szpor</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20Witczak"> K. Witczak</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Storman"> M. Storman</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Orchel"> A. Orchel</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20Hodorowicz-Zaniewska"> D. Hodorowicz-Zaniewska</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20Oko%C5%84"> K. Okoń</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Klimkowska"> A. Klimkowska</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Core needle biopsy (CNB) is well established as an important diagnostic tool in diagnosing breast cancer and it is now considered the initial method of choice for diagnosing breast disease. In comparison to fine needle aspiration (FNA), CNB provides more architectural information allowing for the evaluation of prognostic and predictive factors for breast cancer, including histological grade—one of three prognostic factors used to calculate the Nottingham Prognostic Index. Several studies have previously described the concordance rate between CNB and surgical excision specimen in determination of histological grade (HG). The concordance rate previously ascribed to overall grade varies widely across literature, ranging from 59-91%. The aim of this study is to see how the data looks like in material at authors’ institution and are the results as compared to those described in previous literature. The study population included 157 women with a breast tumor who underwent a core needle biopsy for breast carcinoma and a subsequent surgical excision of the tumor. Both materials were evaluated for the determination of histological grade (scale from 1 to 3). HG was assessed only in core needle biopsies containing at least 10 well preserved HPF with invasive tumor. The degree of concordance between CNB and surgical excision specimen for the determination of tumor grade was assessed by Cohen’s kappa coefficient. The level of agreement between core needle biopsy and surgical resection specimen for overall histologic grading was 73% (113 of 155 cases). CNB correctly predicted the grade of the surgical excision specimen in 21 cases for grade 1 tumors (Kappa coefficient κ = 0.525 95% CI (0.3634; 0.6818), 52 cases for grade 2 (Kappa coefficient κ = 0.5652 95% CI (0.458; 0.667) and 40 cases for stage 3 tumors (Kappa coefficient κ = 0.6154 95% CI (0.4862; 0.7309). The highest level of agreement was observed in grade 3 malignancies. In 9 of 42 (21%) discordant cases, the grade was higher in the CNB than in the surgical excision. This composed 6% of the overall discordance. These results correspond to the noted in the literature, showing that underestimation occurs more frequently than overestimation. This study shows that authors’ institution’s histologic grading of CNBs and surgical excisions shows a fairly good correlation and is consistent with findings in previous reports. Despite the inevitable limitations of CNB, CNB is an effective method for diagnosing breast cancer and managing treatment options. Assessment of tumour grade by CNB is useful for the planning of treatment, so in authors’ opinion it is worthy to implement it in daily practice. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=breast%20cancer" title="breast cancer">breast cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=concordance" title=" concordance"> concordance</a>, <a href="https://publications.waset.org/abstracts/search?q=core%20needle%20biopsy" title=" core needle biopsy"> core needle biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=histological%20grade" title=" histological grade"> histological grade</a> </p> <a href="https://publications.waset.org/abstracts/136072/histological-grade-concordance-between-core-needle-biopsy-and-corresponding-surgical-specimen-in-breast-carcinoma" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/136072.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">229</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2126</span> Pattern of Biopsy Proven Renal Disease and Association between the Clinical Findings with Renal Pathology in Eastern Nepal</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Manish%20Subedi">Manish Subedi</a>, <a href="https://publications.waset.org/abstracts/search?q=Bijay%20Bartaula"> Bijay Bartaula</a>, <a href="https://publications.waset.org/abstracts/search?q=Ashok%20R.%20Pant"> Ashok R. Pant</a>, <a href="https://publications.waset.org/abstracts/search?q=Purbesh%20Adhikari"> Purbesh Adhikari</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanjib%20K.%20Sharma"> Sanjib K. Sharma</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The pattern of glomerular disease varies worldwide. In absence of kidney disease/Kidney biopsy registry in Nepal, the exact etiology of different forms of glomerular disease is primarily unknown in our country. Method: We retrospectively analyzed 175 cases of renal biopsies performed from dated September 2014 to August 2016 at B. P. Koirala Institute of Health Sciences, Dharan, Nepal. Results: The commonest indication for renal biopsy was nephrotic syndrome (34.9%), followed by Systemic lupus erythematosus with suspected renal involvement (22.3%). Majority of patients were in the 30-60 year bracket (57.2%), with the mean age of the patients being 35.37 years. The average number of glomeruli per core was 13, with inadequate sampling in 5.1%. IgA nephropathy (17%) was found to be the most common primary glomerular disease, followed by membranous nephropathy (14.6%) and FSGS (14.6%). The commonest secondary glomerular disease was lupus nephritis. Complications associated with renal biopsy were pain at biopsy site in 18% of cases, hematuria in 6% and perinephric hematoma in 4% cases. Conclusion: The commonest primary and secondary glomerular disease was IgA nephropathy and lupus nephritis respectively. The high prevalence of Systemic lupus erythematosus with lupus nephritis among Nepalese in comparison with other developing countries warrants further evaluation. As an initial attempt towards documentation of glomerular diseases in the national context, this study should serve as a stepping stone towards the eventual establishment of a full-fledged national registry of glomerular diseases in Nepal. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=glomerular" title="glomerular">glomerular</a>, <a href="https://publications.waset.org/abstracts/search?q=Nepal" title=" Nepal"> Nepal</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20biopsy" title=" renal biopsy"> renal biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=systemic%20lupus%20erythematoses" title=" systemic lupus erythematoses"> systemic lupus erythematoses</a> </p> <a href="https://publications.waset.org/abstracts/80240/pattern-of-biopsy-proven-renal-disease-and-association-between-the-clinical-findings-with-renal-pathology-in-eastern-nepal" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/80240.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">229</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2125</span> Importance of Prostate Volume, Prostate Specific Antigen Density and Free/Total Prostate Specific Antigen Ratio for Prediction of Prostate Cancer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aliseydi%20Bozkurt">Aliseydi Bozkurt</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objectives: Benign prostatic hyperplasia (BPH) is the most common benign disease, and prostate cancer (PC) is malign disease of the prostate gland. Transrectal ultrasound-guided biopsy (TRUS-bx) is one of the most important diagnostic tools in PC diagnosis. Identifying men at increased risk for having a biopsy detectable prostate cancer should consider prostate specific antigen density (PSAD), f/t PSA Ratio, an estimate of prostate volume. Method: We retrospectively studied 269 patients who had a prostate specific antigen (PSA) score of 4 or who had suspected rectal examination at any PSA level and received TRUS-bx between January 2015 and June 2018 in our clinic. TRUS-bx was received by 12 experienced urologists with 12 quadrants. Prostate volume was calculated prior to biopsy together with TRUS. Patients were classified as malignant and benign at the end of pathology. Age, PSA value, prostate volume in transrectal ultrasonography, corpuscle biopsy, biopsy pathology result, the number of cancer core and Gleason score were evaluated in the study. The success rates of PV, PSAD, and f/tPSA were compared in all patients and those with PSA 2.5-10 ng/mL and 10.1-30 ng/mL tp foresee prostate cancer. Result: In the present study, in patients with PSA 2.5-10 ng/ml, PV cut-off value was 43,5 mL (n=42 < 43,5 mL and n=102 > 43,5 mL) while in those with PSA 10.1-30 ng/mL prostate volüme (PV) cut-off value was found 61,5 mL (n=31 < 61,5 mL and n=36 > 61,5 mL). Total PSA values in the group with PSA 2.5-10 ng/ml were found lower (6.0 ± 1.3 vs 6.7 ± 1.7) than that with PV < 43,5 mL, this value was nearly significant (p=0,043). In the group with PSA value 10.1-30 ng/mL, no significant difference was found (p=0,117) in terms of total PSA values between the group with PV < 61,5 mL and that with PV > 61,5 mL. In the group with PSA 2.5-10 ng/ml, in patients with PV < 43,5 mL, f/t PSA value was found significantly lower compared to the group with PV > 43,5 mL (0.21 ± 0.09 vs 0.26 ± 0.09 p < 0.001 ). Similarly, in the group with PSA value of 10.1-30 ng/mL, f/t PSA value was found significantly lower in patients with PV < 61,5 mL (0.16 ± 0.08 vs 0.23 ± 0.10 p=0,003). In the group with PSA 2.5-10 ng/ml, PSAD value in patients with PV < 43,5 mL was found significantly higher compared to those with PV > 43,5 mL (0.17 ± 0.06 vs 0.10 ± 0.03 p < 0.001). Similarly, in the group with PSA value 10.1-30 ng/mL PSAD value was found significantly higher in patients with PV < 61,5 mL (0.47 ± 0.23 vs 0.17 ± 0.08 p < 0.001 ). The biopsy results suggest that in the group with PSA 2.5-10 ng/ml, in 29 of the patients with PV < 43,5 mL (69%) cancer was detected while in 13 patients (31%) no cancer was detected. While in 19 patients with PV > 43,5 mL (18,6%) cancer was found, in 83 patients (81,4%) no cancer was detected (p < 0.001). In the group with PSA value 10.1-30 ng/mL, in 21 patients with PV < 61,5 mL (67.7%) cancer was observed while only in10 patients (32.3%) no cancer was seen. In 5 patients with PV > 61,5 mL (13.9%) cancer was found while in 31 patients (86.1%) no cancer was observed (p < 0.001). Conclusions: Identifying men at increased risk for having a biopsy detectable prostate cancer should consider PSA, f/t PSA Ratio, an estimate of prostate volume. Prostate volume in PC was found lower. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=prostate%20cancer" title="prostate cancer">prostate cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=prostate%20volume" title=" prostate volume"> prostate volume</a>, <a href="https://publications.waset.org/abstracts/search?q=prostate%20specific%20antigen" title=" prostate specific antigen"> prostate specific antigen</a>, <a href="https://publications.waset.org/abstracts/search?q=free%2Ftotal%20PSA%20ratio" title=" free/total PSA ratio"> free/total PSA ratio</a> </p> <a href="https://publications.waset.org/abstracts/99812/importance-of-prostate-volume-prostate-specific-antigen-density-and-freetotal-prostate-specific-antigen-ratio-for-prediction-of-prostate-cancer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/99812.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">150</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2124</span> Force Feedback Enabled Syringe for Aspiration and Biopsy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Pelin%20Su%20Firat">Pelin Su Firat</a>, <a href="https://publications.waset.org/abstracts/search?q=Sohyung%20Cho"> Sohyung Cho</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Biopsy or aspiration procedures are known to be complicated as they involve the penetration of a needle through human tissues, including vital organs. This research presents the design of a force sensor-guided device to be used with syringes and needles for aspiration and biopsy. The development of the device was aimed to help accomplish accurate needle placement and increase the performance of the surgeon in navigating the tool and tracking the target. Specifically, a prototype for a force-sensor embedded syringe has been created using 3D (3-Dimensional) modeling and printing techniques in which two different force sensors were used to provide significant force feedback to users during the operations when needles pernitrate different tissues. From the extensive tests using synthetic tissues, it is shown that the proposed syringe design has accomplished the desired accuracy, efficiency, repeatability, and effectiveness. Further development is desirable through usability tests. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biopsy" title="biopsy">biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=syringe" title=" syringe"> syringe</a>, <a href="https://publications.waset.org/abstracts/search?q=force%20sensors" title=" force sensors"> force sensors</a>, <a href="https://publications.waset.org/abstracts/search?q=haptic%20feedback" title=" haptic feedback"> haptic feedback</a> </p> <a href="https://publications.waset.org/abstracts/183278/force-feedback-enabled-syringe-for-aspiration-and-biopsy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/183278.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">69</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2123</span> Correlation Between Different Radiological Findings and Histopathological diagnosis of Breast Diseases: Retrospective Review Conducted Over Sixth Years in King Fahad University Hospital in Eastern Province, Saudi Arabia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sadeem%20Aljamaan">Sadeem Aljamaan</a>, <a href="https://publications.waset.org/abstracts/search?q=Reem%20Hariri"> Reem Hariri</a>, <a href="https://publications.waset.org/abstracts/search?q=Rahaf%20Alghamdi"> Rahaf Alghamdi</a>, <a href="https://publications.waset.org/abstracts/search?q=Batool%20Alotaibi"> Batool Alotaibi</a>, <a href="https://publications.waset.org/abstracts/search?q=Batool%20Alsenan"> Batool Alsenan</a>, <a href="https://publications.waset.org/abstracts/search?q=Lama%20Althunayyan"> Lama Althunayyan</a>, <a href="https://publications.waset.org/abstracts/search?q=Areej%20Alnemer"> Areej Alnemer</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of this study is to correlate between radiological findings and histopathological results in regard to the breast imaging-reporting and data system scores, size of breast masses, molecular subtypes and suspicious radiological features, as well as to assess the concordance rate in histological grade between core biopsy and surgical excision among breast cancer patients, followed by analyzing the change of concordance rate in relation to neoadjuvant chemotherapy in a Saudi population. A retrospective review was conducted over 6-year period (2017-2022) on all breast core biopsies of women preceded by radiological investigation. Chi-squared test (χ2) was performed on qualitative data, the Mann-Whitney test for quantitative non-parametric variables, and the Kappa test for grade agreement. A total of 641 cases were included. Ultrasound, mammography, and magnetic resonance imaging demonstrated diagnostic accuracies of 85%, 77.9% and 86.9%; respectively. magnetic resonance imaging manifested the highest sensitivity (72.2%), and the lowest was for ultrasound (61%). Concordance in tumor size with final excisions was best in magnetic resonance imaging, while mammography demonstrated a higher tendency of overestimation (41.9%), and ultrasound showed the highest underestimation (67.7%). The association between basal-like molecular subtypes and the breast imaging-reporting and data system score 5 classifications was statistically significant only for magnetic resonance imaging (p=0.04). Luminal subtypes demonstrated a significantly higher percentage of speculation in mammography. Breast imaging-reporting and data system score 4 manifested a substantial number of benign pathologies in all the 3 modalities. A fair concordance rate (k= 0.212 & 0.379) was demonstrated between excision and the preceding core biopsy grading with and without neoadjuvant therapy, respectively. The results demonstrated a down-grading in cases post-neoadjuvant therapy. In cases who did not receive neoadjuvant therapy, underestimation of tumor grade in biopsy was evident. In summary, magnetic resonance imaging had the highest sensitivity, specificity, positive predictive value and accuracy of both diagnosis and estimation of tumor size. Mammography demonstrated better sensitivity than ultrasound and had the highest negative predictive value, but ultrasound had better specificity, positive predictive value and accuracy. Therefore, the combination of different modalities is advantageous. The concordance rate of core biopsy grading with excision was not impacted by neoadjuvant therapy. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=breast%20cancer" title="breast cancer">breast cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=mammography" title=" mammography"> mammography</a>, <a href="https://publications.waset.org/abstracts/search?q=MRI" title=" MRI"> MRI</a>, <a href="https://publications.waset.org/abstracts/search?q=neoadjuvant" title=" neoadjuvant"> neoadjuvant</a>, <a href="https://publications.waset.org/abstracts/search?q=pathology" title=" pathology"> pathology</a>, <a href="https://publications.waset.org/abstracts/search?q=US" title=" US"> US</a> </p> <a href="https://publications.waset.org/abstracts/172192/correlation-between-different-radiological-findings-and-histopathological-diagnosis-of-breast-diseases-retrospective-review-conducted-over-sixth-years-in-king-fahad-university-hospital-in-eastern-province-saudi-arabia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/172192.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">82</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2122</span> Seismic Behavior of Short Core Buckling Restrained Braces</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nader%20Hoveidae">Nader Hoveidae</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper investigates the seismic behavior of a new type of buckling restrained braces (BRBs) called "Short Core BRBs" in which a shorter core segment is used as an energy dissipating part and an elastic part is serially connected to the core. It seems that a short core BRB is easy to be fabricated, inspected and replaced after a severe earthquake. In addition, the energy dissipating capacity in a short core BRB is higher because of larger core strains. However, higher core strain demands result in high potential of low-cycle fatigue fracture. In this paper, a strategy is proposed to estimate the minimum core length in a short core BRBs. The seismic behavior of short core buckling restrained brace is experimentally examined. The results revealed that the short core buckling restrained brace is able to sustain large inelastic strains without any significant instability or strength degradation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=short%20core" title="short core">short core</a>, <a href="https://publications.waset.org/abstracts/search?q=Buckling%20Restrained%20Brace" title=" Buckling Restrained Brace"> Buckling Restrained Brace</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20analysis" title=" finite element analysis"> finite element analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=cyclic%20test" title=" cyclic test"> cyclic test</a> </p> <a href="https://publications.waset.org/abstracts/37090/seismic-behavior-of-short-core-buckling-restrained-braces" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/37090.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">360</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2121</span> Diagnostic Efficacy and Usefulness of Digital Breast Tomosynthesis (DBT) in Evaluation of Breast Microcalcifications as a Pre-Procedural Study for Stereotactic Biopsy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Okhee%20Woo">Okhee Woo</a>, <a href="https://publications.waset.org/abstracts/search?q=Hye%20Seon%20Shin"> Hye Seon Shin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: To investigate the diagnostic power of digital breast tomosynthesis (DBT) in evaluation of breast microcalcifications and usefulness as a pre-procedural study for stereotactic biopsy in comparison with full-field digital mammogram (FFDM) and FFDM plus magnification image (FFDM+MAG). Methods and Materials: An IRB approved retrospective observer performance study on DBT, FFDM, and FFDM+MAG was done. Image quality was rated in 5-point scoring system for lesion clarity (1, very indistinct; 2, indistinct; 3, fair; 4, clear; 5, very clear) and compared by Wilcoxon test. Diagnostic power was compared by diagnostic values and AUC with 95% confidence interval. Additionally, procedural report of biopsy was analysed for patient positioning and adequacy of instruments. Results: DBT showed higher lesion clarity (median 5, interquartile range 4-5) than FFDM (3, 2-4, p-value < 0.0001), and no statistically significant difference to FFDM+MAG (4, 4-5, p-value=0.3345). Diagnostic sensitivity and specificity of DBT were 86.4% and 92.5%; FFDM 70.4% and 66.7%; FFDM+MAG 93.8% and 89.6%. The AUCs of DBT (0.88) and FFDM+MAG (0.89) were larger than FFDM (0.59, p-values < 0.0001) but there was no statistically significant difference between DBT and FFDM+MAG (p-value=0.878). In 2 cases with DBT, petit needle could be appropriately prepared; and other 3 without DBT, patient repositioning was needed. Conclusion: DBT showed better image quality and diagnostic values than FFDM and equivalent to FFDM+MAG in the evaluation of breast microcalcifications. Evaluation with DBT as a pre-procedural study for breast stereotactic biopsy can lead to more accurate localization and successful biopsy and also waive the need for additional magnification images. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=DBT" title="DBT">DBT</a>, <a href="https://publications.waset.org/abstracts/search?q=breast%20cancer" title=" breast cancer"> breast cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=stereotactic%20biopsy" title=" stereotactic biopsy"> stereotactic biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=mammography" title=" mammography"> mammography</a> </p> <a href="https://publications.waset.org/abstracts/82986/diagnostic-efficacy-and-usefulness-of-digital-breast-tomosynthesis-dbt-in-evaluation-of-breast-microcalcifications-as-a-pre-procedural-study-for-stereotactic-biopsy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/82986.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">304</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2120</span> Liquid Biopsy and Screening Biomarkers in Glioma Grading</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abdullah%20Abdu%20Qaseem%20Shamsan">Abdullah Abdu Qaseem Shamsan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Gliomas represent the most frequent, heterogeneous group of tumors arising from glial cells, characterized by difficult monitoring, poor prognosis, and fatality. Tissue biopsy is an established procedure for tumor cell sampling that aids diagnosis, tumor grading, and prediction of prognosis. We studied and compared the levels of liquid biopsy markers in patients with different grades of glioma. Also, it tried to establish the potential association between glioma and specific blood groups antigen. Result: 78 patients were identified, among whom maximum percentage with glioblastoma possessed blood group O+ (53.8%). The second highest frequency had blood group A+ (20.4%), followed by B+ (9.0%) and A- (5.1%), and least with O-. Liquid biopsy biomarkers comprised of ALT, LDH, lymphocytes, Urea, Alkaline phosphatase, AST Neutrophils, and CRP. The levels of all the components increased significantly with the severity of glioma, with maximum levels seen in glioblastoma (grade IV), followed by grade III and grade II respectively. Conclusion: Gliomas possess significant clinical challenges due to their progression with heterogeneous nature and aggressive behavior. Liquid biopsy is a non-invasive approach which aids to establish the status of the patient and determine the tumor grade, therefore may show diagnostic and prognostic utility. Additionally, our study provides evidence to demonstrate the role of ABO blood group antigens in the development of glioma. However, future clinical research on liquid biopsy will improve the sensitivity and specificity of these tests and validate their clinical usefulness to guide treatment approaches. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=GBM%3A%20glioblastoma%20multiforme" title="GBM: glioblastoma multiforme">GBM: glioblastoma multiforme</a>, <a href="https://publications.waset.org/abstracts/search?q=CT%3A%20computed%20tomography" title=" CT: computed tomography"> CT: computed tomography</a>, <a href="https://publications.waset.org/abstracts/search?q=MRI%3A%20magnetic%20resonance%20imaging" title=" MRI: magnetic resonance imaging"> MRI: magnetic resonance imaging</a>, <a href="https://publications.waset.org/abstracts/search?q=ctRNA%3A%20circulating%20tumor%20RNA" title=" ctRNA: circulating tumor RNA"> ctRNA: circulating tumor RNA</a> </p> <a href="https://publications.waset.org/abstracts/185991/liquid-biopsy-and-screening-biomarkers-in-glioma-grading" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/185991.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">51</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2119</span> NFC Kenaf Core Graphene Paper: In-situ Method Application </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20A.%20Izzati">M. A. Izzati</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Rosazley"> R. Rosazley</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20W.%20Fareezal"> A. W. Fareezal</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Z.%20Shazana"> M. Z. Shazana</a>, <a href="https://publications.waset.org/abstracts/search?q=I.%20Rushdan"> I. Rushdan</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Jani"> M. Jani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Ultrasonic probe were using to produce nanofibrillated cellulose (NFC) kenaf core. NFC kenaf core and graphene was mixed using in-situ method with the 5V voltage for 24 hours. The resulting NFC graphene paper was characterized by field emission scanning electron microscopy (FESEM), fourier transformed infrared (FTIR) spectra and thermogavimetric analysis (TGA). The properties of NFC kenaf core graphene paper are compared with properties of pure NFC kenaf core paper. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=NFC" title="NFC">NFC</a>, <a href="https://publications.waset.org/abstracts/search?q=kenaf%20core" title=" kenaf core"> kenaf core</a>, <a href="https://publications.waset.org/abstracts/search?q=graphene" title=" graphene"> graphene</a>, <a href="https://publications.waset.org/abstracts/search?q=in-situ%20method" title=" in-situ method"> in-situ method</a> </p> <a href="https://publications.waset.org/abstracts/17245/nfc-kenaf-core-graphene-paper-in-situ-method-application" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/17245.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">394</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2118</span> Comparison between Transient Elastography (FibroScan) and Liver Biopsy for Diagnosis of Hepatic Fibrosis in Chronic Hepatitis C Genotype 4</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gamal%20Shiha">Gamal Shiha</a>, <a href="https://publications.waset.org/abstracts/search?q=Seham%20Seif"> Seham Seif</a>, <a href="https://publications.waset.org/abstracts/search?q=Shahera%20Etreby"> Shahera Etreby</a>, <a href="https://publications.waset.org/abstracts/search?q=Khaled%20Zalata"> Khaled Zalata</a>, <a href="https://publications.waset.org/abstracts/search?q=Waleed%20Samir"> Waleed Samir</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Transient Elastography (TE; FibroScan®) is a non-invasive technique to assess liver fibrosis. Aim: To compare TE and liver biopsy in hepatitis C virus (HCV) patients, genotype IV and evaluate the effect of steatosis and schistosomiasis on FibroScan. Methods: The fibrosis stage (METAVIR Score) TE, was assessed in 519 patients. The diagnostic performance of FibroScan is assessed by calculating the area under the receiver operating characteristic curves (AUROCs). Results: The cut-off value of ≥ F2 was 8.55 kPa, ≥ F3 was 10.2 kPa and cirrhosis = F4 was 16.3 kPa. The positive predictive value and negative predictive value were 70.1% and 81.7% for the diagnosis of ≥ F2, 62.6% and 96.22% for F ≥ 3, and 27.7% and 100% for F4. No significant difference between schistosomiasis, steatosis degree and FibroScan measurements. Conclusion: Fibroscan could accurately predict liver fibrosis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chronic%20hepatitis%20C" title="chronic hepatitis C">chronic hepatitis C</a>, <a href="https://publications.waset.org/abstracts/search?q=FibroScan" title=" FibroScan"> FibroScan</a>, <a href="https://publications.waset.org/abstracts/search?q=liver%20biopsy" title=" liver biopsy"> liver biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=liver%20fibrosis" title=" liver fibrosis"> liver fibrosis</a> </p> <a href="https://publications.waset.org/abstracts/3662/comparison-between-transient-elastography-fibroscan-and-liver-biopsy-for-diagnosis-of-hepatic-fibrosis-in-chronic-hepatitis-c-genotype-4" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/3662.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">409</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2117</span> Computed Tomography Guided Bone Biopsies: Experience at an Australian Metropolitan Hospital</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=K.%20Hinde">K. Hinde</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Bookun"> R. Bookun</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Tran"> P. Tran</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Percutaneous CT guided biopsies provide a fast, minimally invasive, cost effective and safe method for obtaining tissue for histopathology and culture. Standards for diagnostic yield vary depending on whether the tissue is being obtained for histopathology or culture. We present a retrospective audit from Western Health in Melbourne Australia over a 12-month period which aimed to determine the diagnostic yield, technical success and complication rate for CT guided bone biopsies and identify factors affecting these results. The digital imaging storage program (Synapse Picture Archiving and Communication System – Fujifilm Australia) was analysed with key word searches from October 2015 to October 2016. Nineteen CT guided bone biopsies were performed during this time. The most common referring unit was oncology, work up imaging included CT, MRI, bone scan and PET scan. The complication rate was 0%, overall diagnostic yield was 74% with a technical success of 95%. When performing biopsies for histologic analysis diagnostic yield was 85% and when performing biopsies for bacterial culture diagnostic yield was 60%. There was no significant relationship identified between size of lesion, distance of lesion to skin, lesion appearance on CT, the number of samples taken or gauge of needle to diagnostic yield or technical success. CT guided bone biopsy at Western Health meets the standard reported at other major clinical centres for technical success and safety. It is a useful investigation in identification of primary malignancy in distal bone metastases. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20biopsy" title="bone biopsy">bone biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=computed%20tomography" title=" computed tomography"> computed tomography</a>, <a href="https://publications.waset.org/abstracts/search?q=core%20biopsy" title=" core biopsy"> core biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=histopathology" title=" histopathology"> histopathology</a> </p> <a href="https://publications.waset.org/abstracts/77030/computed-tomography-guided-bone-biopsies-experience-at-an-australian-metropolitan-hospital" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/77030.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">200</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2116</span> Integration of an Augmented Reality System for the Visualization of the HRMAS NMR Analysis of Brain Biopsy Specimens Using the Brainlab Cranial Navigation System</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abdelkrim%20Belhaoua">Abdelkrim Belhaoua</a>, <a href="https://publications.waset.org/abstracts/search?q=Jean-Pierre%20Radoux"> Jean-Pierre Radoux</a>, <a href="https://publications.waset.org/abstracts/search?q=Mariana%20Kuras"> Mariana Kuras</a>, <a href="https://publications.waset.org/abstracts/search?q=Vincent%20R%C3%A9camier"> Vincent Récamier</a>, <a href="https://publications.waset.org/abstracts/search?q=Martial%20Piotto"> Martial Piotto</a>, <a href="https://publications.waset.org/abstracts/search?q=Karim%20Elbayed"> Karim Elbayed</a>, <a href="https://publications.waset.org/abstracts/search?q=Fran%C3%A7ois%20Proust"> François Proust</a>, <a href="https://publications.waset.org/abstracts/search?q=Izzie%20Namer"> Izzie Namer</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper proposes an augmented reality system dedicated to neurosurgery in order to assist the surgeon during an operation. This work is part of the ExtempoRMN project (Funded by Bpifrance) which aims at analyzing during a surgical operation the metabolic content of tumoral brain biopsy specimens by HRMAS NMR. Patients affected with a brain tumor (gliomas) frequently need to undergo an operation in order to remove the tumoral mass. During the operation, the neurosurgeon removes biopsy specimens using image-guided surgery. The biopsy specimens removed are then sent for HRMAS NMR analysis in order to obtain a better diagnosis and prognosis. Image-guided refers to the use of MRI images and a computer to precisely locate and target a lesion (abnormal tissue) within the brain. This is performed using preoperative MRI images and the BrainLab neuro-navigation system. With the patient MRI images loaded on the Brainlab Cranial neuro-navigation system in the operating theater, surgeons can better identify their approach before making an incision. The Brainlab neuro-navigation tool tracks in real time the position of the instruments and displays their position on the patient MRI data. The results of the biopsy analysis by 1H HRMAS NMR are then sent back to the operating theater and superimposed on the 3D localization system directly on the MRI images. The method we have developed to communicate between the HRMAS NMR analysis software and Brainlab makes use of a combination of C++, VTK and the Insight Toolkit using OpenIGTLink protocol. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=neuro-navigation" title="neuro-navigation">neuro-navigation</a>, <a href="https://publications.waset.org/abstracts/search?q=augmented%20reality" title=" augmented reality"> augmented reality</a>, <a href="https://publications.waset.org/abstracts/search?q=biopsy" title=" biopsy"> biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=BrainLab" title=" BrainLab"> BrainLab</a>, <a href="https://publications.waset.org/abstracts/search?q=HR-MAS%20NMR" title=" HR-MAS NMR"> HR-MAS NMR</a> </p> <a href="https://publications.waset.org/abstracts/57089/integration-of-an-augmented-reality-system-for-the-visualization-of-the-hrmas-nmr-analysis-of-brain-biopsy-specimens-using-the-brainlab-cranial-navigation-system" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/57089.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">363</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2115</span> Biopsy Proven Polyoma (BK) Virus in Saudi Kidney Recipients – Prevalence, Clinicopathological Features and Clinico-Pathological Correlations </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sarah%20Hamdan%20Al-Jahdali">Sarah Hamdan Al-Jahdali</a>, <a href="https://publications.waset.org/abstracts/search?q=Khaled%20Alsaad"> Khaled Alsaad</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdullah%20Al-Sayyari"> Abdullah Al-Sayyari</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objectives: To study the prevalence, clinicopathological features, risk factors and outcome of biopsy proven polyoma (BK) virus infection among Saudi kidney transplant recipients and compare them to negative BK virus group. Methods: We retrospectively reviewed the charts of all the patients with biopsy-proven polyoma (BK) virus infection in King Abdulaziz Medical City in Riyadh between 2005 and 2011. The details of clinical presentation, the indication for kidney biopsy, the laboratory findings at presentation, the natural history of the disease, thepathological findings, the prognosis as well as the response to therapy were all recorded. Results: Kidney biopsy was performed in 37 cases of unexplained graft dysfunction. BK virus was found in 10 (27%). Out of those 10, 3 (30%) ended with graft failure. BK virus occurred in all patients who received ATG induction therapy 100% versus 59.3% in the non BK virus patients (p=0.06). Furthermore, the risk of BK virus was much less in those who received acyclovir as an anti-viral prophylaxis as compared to those who did not receive it (p=0.01). Also, patients with BK virus weighed much less (mean 46.7±20.6 Kgs) than those without BK virus at time of transplantation (mean 64.3±12.1). Graft survival was better among deceased donor kidneys compared to living ones (P=0.016) and with older age (P=0.005). Conclusion: Our findings suggest the involvement of ATG induction therapy, the lack of antiviral prophylaxis therapy and lower weight at transplant as significant risk factors for the development of BK virus infection. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=BKVAN" title="BKVAN">BKVAN</a>, <a href="https://publications.waset.org/abstracts/search?q=BKV" title=" BKV"> BKV</a>, <a href="https://publications.waset.org/abstracts/search?q=kidney%20transpant" title=" kidney transpant"> kidney transpant</a>, <a href="https://publications.waset.org/abstracts/search?q=Saudi%20Arabia" title=" Saudi Arabia"> Saudi Arabia</a> </p> <a href="https://publications.waset.org/abstracts/30336/biopsy-proven-polyoma-bk-virus-in-saudi-kidney-recipients-prevalence-clinicopathological-features-and-clinico-pathological-correlations" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30336.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">284</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2114</span> Classifying the Role of Technology in Technology Development</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hyun%20Joung%20No">Hyun Joung No</a>, <a href="https://publications.waset.org/abstracts/search?q=Chul%20Lee"> Chul Lee</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Even though technology evolves and develops through interaction with each other, not all technologies contribute to the development of technology equally. While some technologies play a central role in developing technology, others play a secondary role. The role of the technological components can be classified as core or non-core (peripheral) technology. The core technologies have a considerable knowledge interaction with other technological components while the non-core technologies barely interact with others within the system. This study introduces the concept that classifies the technological components into core or peripheral technology according to their role and importance in the technology field. The study adapted the social network analysis to examine the relationship between technological components. Using a continuous core-periphery analysis, it identifies the technological network structure and classifies the core and peripheral nodes. Based on their knowledge inflow/outflow direction and their dependence/influence on core technologies, the technological clusters are classified into four categories: (1) high dependence and high influence on core technology, (2) high dependence and low influence on core technology, (3) low dependence and high influence on core technology, and (4) low dependence and low influence on core technology. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=core%20technology" title="core technology">core technology</a>, <a href="https://publications.waset.org/abstracts/search?q=periphery%20technology" title=" periphery technology"> periphery technology</a>, <a href="https://publications.waset.org/abstracts/search?q=technological%20components" title=" technological components"> technological components</a>, <a href="https://publications.waset.org/abstracts/search?q=technological%20role" title=" technological role"> technological role</a> </p> <a href="https://publications.waset.org/abstracts/79729/classifying-the-role-of-technology-in-technology-development" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/79729.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">538</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2113</span> 99mTc Scintimammography in an Equivocal Breast Lesion</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Malak%20Shawky%20Matter%20Elyas">Malak Shawky Matter Elyas</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Early detection of breast cancer is the main tool to decrease morbidity and mortality rates. Many diagnostic tools are used, such as mammograms, ultrasound and magnetic resonance imaging, but none of them is conclusive, especially in very small sizes, less than 1 cm. So, there is a need for more accurate tools. Patients and methods: This study involved 13 patients with different breast lesions. 6 Patients had breast cancer, and one of them had metastatic axillary lymph nodes without clinically nor mammographically detected breast mass proved by biopsy and histopathology. Of the other 7 Patients, 4 of them had benign breast lesions proved by biopsy and histopathology, and 3 Patients showed Equivocal breast lesions on a mammogram. A volume of 370-444Mbq of (99m) Tc/ bombesin was injected. Dynamic 1-min images by Gamma Camera were taken for 20 minutes immediately after injection in the anterior view. Thereafter, two static images in anterior and prone lateral views by Gamma Camera were taken for 5 minutes. Finally, single-photon emission computed tomography images were taken for each patient. The definitive diagnosis was based on biopsy and histopathology. Results: 6 Patients with breast cancer proved by biopsy and histopathology showed Positive findings on Sestamibi (Scintimammography). 1 out of 4 Patients with benign breast lesions proved by biopsy and histopathology showed Positive findings on Sestamibi (Scintimammography) while the other 3 Patients showed Negative findings on Sestamibi. 3 Patients out of 3 Patients with equivocal breast findings on mammogram showed Positive Findings on Sestamibi (Scintimammography) and proved by biopsy and histopathology. Conclusions: While we agree that Scintimammography will not replace mammograms as a mass screening tool, we believe that many patients will benefit from Scintimammography, especially women with dense breast tissues and in the presence of breast implants that are difficult to diagnose by mammogram, wherein its sensitivity is low and in women with metastatic axillary lymph nodes without clinically nor mammographically findings. We can use Scintimammography in sentinel lymph node mapping as a more accurate tool, especially since it is non-invasive. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=breast." title="breast.">breast.</a>, <a href="https://publications.waset.org/abstracts/search?q=radiodiagnosis" title=" radiodiagnosis"> radiodiagnosis</a>, <a href="https://publications.waset.org/abstracts/search?q=lifestyle" title=" lifestyle"> lifestyle</a>, <a href="https://publications.waset.org/abstracts/search?q=surgery" title=" surgery"> surgery</a> </p> <a href="https://publications.waset.org/abstracts/189033/99mtc-scintimammography-in-an-equivocal-breast-lesion" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/189033.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">31</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2112</span> Biopsy or Biomarkers: Which Is the Sample of Choice in Assessment of Liver Fibrosis?</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20H.%20Atef">S. H. Atef</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20H.%20Mahmoud"> N. H. Mahmoud</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Abdrahman"> S. Abdrahman</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Fattoh"> A. Fattoh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The aim of the study is to assess the diagnostic value of fibrotest and hyaluronic acid in discriminate between insignificant and significant fibrosis. Also, to find out if these parameters could replace liver biopsy which is currently used for selection of chronic hepatitis C patients eligible for antiviral therapy. Study design: This study was conducted on 52 patients with HCV RNA detected by polymerase chain reaction (PCR) who had undergone liver biopsy and attending the internal medicine clinic at Ain Shams University Hospital. Liver fibrosis was evaluated according to the METAVIR scoring system on a scale of F0 to F4. Biochemical markers assessed were: alpha-2 macroglobulin (α2-MG), apolipoprotein A1 (Apo-A1), haptoglobin, gamma-glutamyl transferase (GGT), total bilirubin (TB) and hyaluronic acid (HA). The fibrotest score was computed after adjusting for age and gender. Predictive values and ROC curves were used to assess the accuracy of fibrotest and HA results. Results: For fibrotest, the observed area under curve for the discrimination between minimal or no fibrosis (F0-F1) and significant fibrosis (F2-F4) was 0.6736 for cutoff value 0.19 with sensitivity of 84.2% and specificity of 85.7%. For HA, the sensitivity was 89.5% and specificity was 85.7% and area under curve was 0.540 at the best cutoff value 71 mg/dL. Multi-use of both parameters, HA at 71 mg/dL with fibrotest score at 0.22 give a sensitivity 89.5%, specificity 100 and efficacy 92.3% (AUC 0.895). Conclusion: The use of both fibrotest score and HA could be as alternative to biopsy in most patients with chronic hepaitis C putting in consideration some limitations of the proposed markers in evaluating liver fibrosis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fibrotest" title="fibrotest">fibrotest</a>, <a href="https://publications.waset.org/abstracts/search?q=liver%20fibrosis" title=" liver fibrosis"> liver fibrosis</a>, <a href="https://publications.waset.org/abstracts/search?q=HCV%20RNA" title=" HCV RNA"> HCV RNA</a>, <a href="https://publications.waset.org/abstracts/search?q=biochemical%20markers" title=" biochemical markers"> biochemical markers</a> </p> <a href="https://publications.waset.org/abstracts/37231/biopsy-or-biomarkers-which-is-the-sample-of-choice-in-assessment-of-liver-fibrosis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/37231.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">287</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2111</span> Flexural Test of Diversing Foam Core Sandwich Composites </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Santhana%20Krishnan%20R">Santhana Krishnan R</a>, <a href="https://publications.waset.org/abstracts/search?q=Preetha%20C"> Preetha C</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Sandwich construction with strong and stiffness facing and light weight cores is increasingly cores being used in structures where the predominant loads are flexural. The objective of this study is to improve the flexural performances of foam core sandwich composite via structural core modifications considering the ease of application. The performances of single core perforated and divided core perforated sandwich composites are compared with each other. The future demands of sandwich composites in recent years on aeronautics and marine industries are being increasing in their research needs and these materials has their superior properties for upgrading engineering products. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=sandwich%20composites" title="sandwich composites">sandwich composites</a>, <a href="https://publications.waset.org/abstracts/search?q=perforated%20cores" title=" perforated cores"> perforated cores</a>, <a href="https://publications.waset.org/abstracts/search?q=flexural%20test" title=" flexural test"> flexural test</a>, <a href="https://publications.waset.org/abstracts/search?q=single%20and%20divided%20core%20perforated" title=" single and divided core perforated"> single and divided core perforated</a> </p> <a href="https://publications.waset.org/abstracts/128162/flexural-test-of-diversing-foam-core-sandwich-composites" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/128162.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">160</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2110</span> Mammotome Vacuum-Assisted Breast Biopsy versus Conventional Open Surgery: A Meta-Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dylan%20Shiting%20Lu">Dylan Shiting Lu</a>, <a href="https://publications.waset.org/abstracts/search?q=Samson%20Okello"> Samson Okello</a>, <a href="https://publications.waset.org/abstracts/search?q=Anita%20Chunyan%20Wei"> Anita Chunyan Wei</a>, <a href="https://publications.waset.org/abstracts/search?q=Daniel%20Xiao%20Li"> Daniel Xiao Li</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Mammotome vacuum-assisted breast biopsy (MVB) introduced in 1995 can be used for the removal of benign breast lesions. Whether or not MVB is a better option compared to conventional open surgery is inconclusive. We aim to compare the clinical and patient-related outcomes between MVB and open surgery to remove benign breast tumors less than 5 cm in women. We searched English and Chinese electronic databases with the keywords of Mammotome, clinical trial (CT), vacuum-assisted breast biopsy for studies comparing MVB and open surgery until May 2021. We performed a systematic review and random-effects meta-analysis to compare incision size, operation time, intraoperative blood loss, healing time, scar length, patient satisfaction, postoperative hematoma rate, wound infection rate, postoperative ecchymosis, and postoperative sunken skin among those who have Mammotome and those who have surgery. Our analysis included nine randomized CTs with 1155 total patients (575 Mammotome, 580 surgery) and mean age 40.32 years (standard deviation 3.69). We found statistically significant favorable outcomes for Mammotome including blood loss (ml) [standardized mean difference SMD -5.03, 95%CI (-7.30, -2.76)], incision size (cm) [SMD -12.22, 95%CI (-17.40, -7.04)], operation time (min) [SMD -6.66, 95%CI (-9.01, -4.31)], scar length (cm) [SMD -7.06, 95%CI (-10.76, -3.36)], healing time (days) [SMD -6.57, 95%CI (-10.18, -2.95)], and patient satisfaction [relative risk RR 0.38, 95%CI (0.13, 1.08)]. In conclusion, Mammotome vacuum-assisted breast biopsy compared to open surgery shows better clinical and patient-related outcomes. Further studies should be done on whether or not MVB is a better option for benign breast tumors excision. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=clinical%20and%20patient%20outcomes" title="clinical and patient outcomes">clinical and patient outcomes</a>, <a href="https://publications.waset.org/abstracts/search?q=open%20surgery" title=" open surgery"> open surgery</a>, <a href="https://publications.waset.org/abstracts/search?q=Mammotome%20vacuum-assisted%20breast%20biopsy" title=" Mammotome vacuum-assisted breast biopsy"> Mammotome vacuum-assisted breast biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=meta-analysis" title=" meta-analysis"> meta-analysis</a> </p> <a href="https://publications.waset.org/abstracts/139607/mammotome-vacuum-assisted-breast-biopsy-versus-conventional-open-surgery-a-meta-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/139607.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">217</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2109</span> Biocompatibility and Sensing Ability of Highly Luminescent Synthesized Core-Shell Quantum Dots</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohan%20Singh%20%20Mehata">Mohan Singh Mehata</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20K.%20Ratnesh"> R. K. Ratnesh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> CdSe, CdSe/ZnS, and CdSe/CdS core-shell quantum dots (QDs) of 3-4 nm were developed by using chemical route and following successive ion layer adsorption and reaction (SILAR) methods. The prepared QDs have been examined by using X-ray diffraction, high-resolution electron microscopy and optical spectroscopy. The photoluminescence (PL) quantum yield (QY) of core-shell QDs increases with respect to the core, indicating that the radiative rate increases by the formation of shell around core, as evident by the measurement of PL lifetime. Further, the PL of bovine serum albumin is quenched strongly by the presence of core-shall QDs and follow the Stern-Volmer (S-V) relation, whereas the lifetime does not follow the S-V relation, demonstrating that the observed quenching is predominantly static in nature. Among all the QDs, the CdSe/ZnS QDs shows the least cytotoxicity hence most biocompatibility. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biocompatibility" title="biocompatibility">biocompatibility</a>, <a href="https://publications.waset.org/abstracts/search?q=core-shell%20quantum%20dots" title=" core-shell quantum dots"> core-shell quantum dots</a>, <a href="https://publications.waset.org/abstracts/search?q=photoluminescence%20and%20lifetime" title=" photoluminescence and lifetime"> photoluminescence and lifetime</a>, <a href="https://publications.waset.org/abstracts/search?q=sensing%20ability" title=" sensing ability"> sensing ability</a> </p> <a href="https://publications.waset.org/abstracts/56638/biocompatibility-and-sensing-ability-of-highly-luminescent-synthesized-core-shell-quantum-dots" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/56638.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">236</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2108</span> Local Buckling of Web-Core and Foam-Core Sandwich Panels</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ali%20N.%20Suri">Ali N. Suri</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmad%20A.%20Al-Makhlufi"> Ahmad A. Al-Makhlufi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Sandwich construction is widely accepted as a method of construction especially in the aircraft industry. It is a type of stressed skin construction formed by bonding two thin faces to a thick core, the faces resist all of the applied edge loads and provide all or nearly all of the required rigidities, the core spaces the faces to increase cross section moment of inertia about common neutral axis and transmit shear between them provides a perfect bond between core and faces is made. Material for face sheets can be of metal or reinforced plastics laminates, core material can be metallic cores of thin sheets forming corrugation or honeycomb, or non-metallic core of Balsa wood, plastic foams, or honeycomb made of reinforced plastics. For in plane axial loading web core and web-foam core Sandwich panels can fail by local buckling of plates forming the cross section with buckling wave length of the order of length of spacing between webs. In this study local buckling of web core and web-foam core Sandwich panels is carried out for given materials of facing and core, and given panel overall dimension for different combinations of cross section geometries. The Finite Strip Method is used for the analysis, and Fortran based computer program is developed and used. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=local%20buckling" title="local buckling">local buckling</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20strip" title=" finite strip"> finite strip</a>, <a href="https://publications.waset.org/abstracts/search?q=sandwich%20panels" title=" sandwich panels"> sandwich panels</a>, <a href="https://publications.waset.org/abstracts/search?q=web%20and%20foam%20core" title=" web and foam core"> web and foam core</a> </p> <a href="https://publications.waset.org/abstracts/7299/local-buckling-of-web-core-and-foam-core-sandwich-panels" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/7299.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">351</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2107</span> Identification of Transformer Core Vibrations and the Effect of Third Harmonic in the Electricity Grid</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Setareh%20Gorji%20Ghalamestani">Setareh Gorji Ghalamestani</a>, <a href="https://publications.waset.org/abstracts/search?q=Lieven%20Vandevelde"> Lieven Vandevelde</a>, <a href="https://publications.waset.org/abstracts/search?q=Jan%20Melkebeek"> Jan Melkebeek</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this work, an experimental technique is applied for the measurements of the vibrations and deformation of a test transformer core. Since the grid voltage contains some higher harmonics, in addition to a purely sinusoidal magnetisation of the core the presence of third harmonic is also studied. The vibrations of the transformer core for points as well as the surface scan of the leg show more deformation in the corners of the leg than the middle of the leg. The influence of the higher harmonic of the magnetisation on the core deformation is also more significant in the corners of the leg. The core deformation shape under a sinusoidal magnetisation with a higher harmonic is more wavy and fluctuating than that under a purely sinusoidal magnetisation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=vibrations%20and%20noise" title="vibrations and noise">vibrations and noise</a>, <a href="https://publications.waset.org/abstracts/search?q=transformer" title=" transformer"> transformer</a>, <a href="https://publications.waset.org/abstracts/search?q=vibration%20measurements" title=" vibration measurements"> vibration measurements</a>, <a href="https://publications.waset.org/abstracts/search?q=laser%20vibrometer" title=" laser vibrometer"> laser vibrometer</a>, <a href="https://publications.waset.org/abstracts/search?q=higher%20harmonic" title=" higher harmonic "> higher harmonic </a> </p> <a href="https://publications.waset.org/abstracts/6336/identification-of-transformer-core-vibrations-and-the-effect-of-third-harmonic-in-the-electricity-grid" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/6336.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">368</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2106</span> Added Value of 3D Ultrasound Image Guided Hepatic Interventions by X Matrix Technology</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Abdel%20Sattar%20Khalil">Ahmed Abdel Sattar Khalil</a>, <a href="https://publications.waset.org/abstracts/search?q=Hazem%20Omar"> Hazem Omar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Image-guided hepatic interventions are integral to the management of infective and neoplastic liver lesions. Over the past decades, 2D ultrasound was used for guidance of hepatic interventions; with the recent advances in ultrasound technology, 3D ultrasound was used to guide hepatic interventions. The aim of this study was to illustrate the added value of 3D image guided hepatic interventions by x matrix technology. Patients and Methods: This prospective study was performed on 100 patients who were divided into two groups; group A included 50 patients who were managed by 2D ultrasonography probe guidance, and group B included 50 patients who were managed by 3D X matrix ultrasonography probe guidance. Thermal ablation was done for 70 patients, 40 RFA (20 by the 2D probe and 20 by the 3D x matrix probe), and 30 MWA (15 by the 2D probe and 15 by the 3D x matrix probe). Chemical ablation (PEI) was done on 20 patients (10 by the 2D probe and 10 by the 3D x matrix probe). Drainage of hepatic collections and biopsy from undiagnosed hepatic focal lesions was done on 10 patients (5 by the 2D probe and 5 by the 3D x matrix probe). Results: The efficacy of ultrasonography-guided hepatic interventions by 3D x matrix probe was higher than the 2D probe but not significantly higher, with a p-value of 0.705, 0.5428 for RFA, MWA respectively, 0.5312 for PEI, 0.2918 for drainage of hepatic collections and biopsy. The complications related to the use of the 3D X matrix probe were significantly lower than the 2D probe, with a p-value of 0.003. The timing of the procedure was shorter by the usage of 3D x matrix probe in comparison to the 2D probe with a p-value of 0.08,0.34 for RFA and PEI and significantly shorter for MWA, and drainage of hepatic collection, biopsy with a P-value of 0.02,0.001 respectively. Conclusions: 3D ultrasonography-guided hepatic interventions by Â x matrix probe have better efficacy, less complication, and shorter time of procedure than the 2D ultrasonography-guided hepatic interventions. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=3D" title="3D">3D</a>, <a href="https://publications.waset.org/abstracts/search?q=X%20matrix" title=" X matrix"> X matrix</a>, <a href="https://publications.waset.org/abstracts/search?q=2D" title=" 2D"> 2D</a>, <a href="https://publications.waset.org/abstracts/search?q=ultrasonography" title=" ultrasonography"> ultrasonography</a>, <a href="https://publications.waset.org/abstracts/search?q=MWA" title=" MWA"> MWA</a>, <a href="https://publications.waset.org/abstracts/search?q=RFA" title=" RFA"> RFA</a>, <a href="https://publications.waset.org/abstracts/search?q=PEI" title=" PEI"> PEI</a>, <a href="https://publications.waset.org/abstracts/search?q=drainage%20of%20hepatic%20collections" title=" drainage of hepatic collections"> drainage of hepatic collections</a>, <a href="https://publications.waset.org/abstracts/search?q=biopsy" title=" biopsy"> biopsy</a> </p> <a href="https://publications.waset.org/abstracts/173809/added-value-of-3d-ultrasound-image-guided-hepatic-interventions-by-x-matrix-technology" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/173809.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">95</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2105</span> Relation between Demodex folliculorum and Rosacea</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maha%20M.%20Eissa">Maha M. Eissa</a>, <a href="https://publications.waset.org/abstracts/search?q=Safia%20M.%20Ali"> Safia M. Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=Sonia%20R.%20Allam"> Sonia R. Allam</a>, <a href="https://publications.waset.org/abstracts/search?q=Ezzat%20A.%20Badawy"> Ezzat A. Badawy</a>, <a href="https://publications.waset.org/abstracts/search?q=Nahed%20M.%20Baddour"> Nahed M. Baddour</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The obligate follicle mite Demodex folliculorum (Df) has been demonstrated in increased numbers in patients with rosacea. The significance of this finding is still not completely understood because many people free of skin disease may also have mites. So, the aim of this work was to study the possible role of Df in patients with rosacea. Facial punch biopsy specimens were taken from patients with rosacea (either telangiectatic, papulopustular, squamous, granulomatous form or with rhinophyma) and age and sex-matched healthy subjects. Results of this study showed that 63.3% of the rosacea patients were harbouring the mite, with a higher incidence in patients with papulopustular form. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Demodex%20folliculorum" title="Demodex folliculorum">Demodex folliculorum</a>, <a href="https://publications.waset.org/abstracts/search?q=histopathology" title=" histopathology"> histopathology</a>, <a href="https://publications.waset.org/abstracts/search?q=punch%20biopsy" title=" punch biopsy"> punch biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=rosacea" title=" rosacea"> rosacea</a> </p> <a href="https://publications.waset.org/abstracts/156841/relation-between-demodex-folliculorum-and-rosacea" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/156841.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">117</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2104</span> The Importance of Oral Mucosal Biopsy Selection Site in Areas of Field Change: A Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Timmis%20W.">Timmis W.</a>, <a href="https://publications.waset.org/abstracts/search?q=Simms%20M."> Simms M.</a>, <a href="https://publications.waset.org/abstracts/search?q=Thomas%20C."> Thomas C.</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This case discusses the management of two floors of mouth (FOM) Squamous Cell Carcinomas (SCC) not identified upon initial biopsy. A 51 year-old male presented with right FOM erythroleukoplakia. Relevant medical history included alcoholic dependence syndrome and alcoholic liver disease. Relevant drug therapy encompassed acamprosate, folic acid, hydroxocobalamin and thiamine. The patient had a 55.5 pack-year smoking history and alcohol dependence from age 14, drinking 16 units/day. FOM incisional biopsy and histopathological analysis diagnosed Carcinoma in situ. Treatment involved wide local excision. Specimen analysis revealed two separate foci of pT1 moderately differentiated SCCs. Carcinoma staging scans revealed no pathological lymphadenopathy, no local invasion or metastasis. SCCs had been excised in completion with narrow margins. MDT discussion concluded that in view of the field changes it would be difficult to identify specific areas needing further excision, although techniques such as Lugol’s Iodine were considered. Further surgical resection, surgical neck management and sentinel lymph node biopsy was offered. The patient declined intervention, primary management involved close monitoring alongside alcohol and smoking cessation referral. Narrow excisional margins can increase carcinoma recurrence risk. Biopsy failed to identify SCCs, despite sampling an area of clinical concern. For gross field change multiple incisional biopsies should be considered to increase chance of accurate diagnosis and appropriate treatment. Coupling of tobacco and alcohol has a synergistic effect, exponentially increasing the relative risk of oral carcinoma development. Tobacco and alcoholic control is fundamental in reducing treatment‑related side effects, recurrence risk and second primary cancer development. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=alcohol%20dependence" title="alcohol dependence">alcohol dependence</a>, <a href="https://publications.waset.org/abstracts/search?q=biopsy" title=" biopsy"> biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=oral%20carcinoma" title=" oral carcinoma"> oral carcinoma</a>, <a href="https://publications.waset.org/abstracts/search?q=tobacco" title=" tobacco"> tobacco</a> </p> <a href="https://publications.waset.org/abstracts/142817/the-importance-of-oral-mucosal-biopsy-selection-site-in-areas-of-field-change-a-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/142817.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">112</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2103</span> Diagnostic Value of Different Noninvasive Criteria of Latent Myocarditis in Comparison with Myocardial Biopsy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Olga%20Blagova">Olga Blagova</a>, <a href="https://publications.waset.org/abstracts/search?q=Yuliya%20Osipova"> Yuliya Osipova</a>, <a href="https://publications.waset.org/abstracts/search?q=Evgeniya%20Kogan"> Evgeniya Kogan</a>, <a href="https://publications.waset.org/abstracts/search?q=Alexander%20Nedostup"> Alexander Nedostup</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: to quantify the value of various clinical, laboratory and instrumental signs in the diagnosis of myocarditis in comparison with morphological studies of the myocardium. Methods: in 100 patients (65 men, 44.7±12.5 years) with «idiopathic» arrhythmias (n = 20) and dilated cardiomyopathy (DCM, n = 80) were performed 71 endomyocardial biopsy (EMB), 13 intraoperative biopsy, 5 study of explanted hearts, 11 autopsy with virus investigation (real-time PCR) of the blood and myocardium. Anti-heart antibodies (AHA) were also measured as well as cardiac CT (n = 45), MRI (n = 25), coronary angiography (n = 47). The comparison group included of 50 patients (25 men, 53.7±11.7 years) with non-inflammatory heart diseases who underwent open heart surgery. Results. Active/borderline myocarditis was diagnosed in 76.0% of the study group and in 21.6% of patients of the comparison group (p < 0.001). The myocardial viral genome was observed more frequently in patients of comparison group than in study group (group (65.0% and 40.2%; p < 0.01. Evaluated the diagnostic value of noninvasive markers of myocarditis. The panel of anti-heart antibodies had the greatest importance to identify myocarditis: sensitivity was 81.5%, positive and negative predictive value was 75.0 and 60.5%. It is defined diagnostic value of non-invasive markers of myocarditis and diagnostic algorithm providing an individual assessment of the likelihood of myocarditis is developed. Conclusion. The greatest significance in the diagnosis of latent myocarditis in patients with 'idiopathic' arrhythmias and DCM have AHA. The use of complex of noninvasive criteria allows estimate the probability of myocarditis and determine the indications for EMB. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=myocarditis" title="myocarditis">myocarditis</a>, <a href="https://publications.waset.org/abstracts/search?q=%22idiopathic%22%20arrhythmias" title=" "idiopathic" arrhythmias"> "idiopathic" arrhythmias</a>, <a href="https://publications.waset.org/abstracts/search?q=dilated%20cardiomyopathy" title=" dilated cardiomyopathy"> dilated cardiomyopathy</a>, <a href="https://publications.waset.org/abstracts/search?q=endomyocardial%20biopsy" title=" endomyocardial biopsy"> endomyocardial biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=viral%20genome" title=" viral genome"> viral genome</a>, <a href="https://publications.waset.org/abstracts/search?q=anti-heart%20antibodies" title=" anti-heart antibodies"> anti-heart antibodies</a> </p> <a href="https://publications.waset.org/abstracts/83648/diagnostic-value-of-different-noninvasive-criteria-of-latent-myocarditis-in-comparison-with-myocardial-biopsy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/83648.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">173</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2102</span> Relation Between Demodex Folliculorum and Rosacea</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maha%20M.%20Eissa">Maha M. Eissa</a>, <a href="https://publications.waset.org/abstracts/search?q=Safia%20M.%20Ali"> Safia M. Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=Sonia%20R.%20Allam"> Sonia R. Allam</a>, <a href="https://publications.waset.org/abstracts/search?q=Ezzat%20A.%20Badawy"> Ezzat A. Badawy</a>, <a href="https://publications.waset.org/abstracts/search?q=Nahid%20M.%20Baddour"> Nahid M. Baddour</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The obligate follicle mite Demodex folliculorum (Df) has been demonstrated in increased numbers in patients with rosacea. The significance of this finding is still not completely understood, because many people free of skin disease may also have mites. So, the aim of this work was to study the possible role of Df in patients with rosacea. Facial punch biopsy specimens were taken from patients with rosacea (either telangiectatic, papulopustular, squamous, granulomatous form or with rhinophyma) and age and sex matched healthy subjects. Results of this study showed that 63.3% of the rosacea patients were harbouring the mite with higher incidence in patients with papulopustular form. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Demodex%20folliculorum" title="Demodex folliculorum">Demodex folliculorum</a>, <a href="https://publications.waset.org/abstracts/search?q=rosacea" title=" rosacea"> rosacea</a>, <a href="https://publications.waset.org/abstracts/search?q=papulopustular" title=" papulopustular"> papulopustular</a>, <a href="https://publications.waset.org/abstracts/search?q=punch%20biopsy" title=" punch biopsy"> punch biopsy</a> </p> <a href="https://publications.waset.org/abstracts/150703/relation-between-demodex-folliculorum-and-rosacea" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/150703.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">120</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2101</span> Study on Clarification of the Core Technology in a Monozukuri Company</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nishiyama%20Toshiaki">Nishiyama Toshiaki</a>, <a href="https://publications.waset.org/abstracts/search?q=Tadayuki%20Kyountani"> Tadayuki Kyountani</a>, <a href="https://publications.waset.org/abstracts/search?q=Nguyen%20Huu%20Phuc"> Nguyen Huu Phuc</a>, <a href="https://publications.waset.org/abstracts/search?q=Shigeyuki%20Haruyama"> Shigeyuki Haruyama</a>, <a href="https://publications.waset.org/abstracts/search?q=Oke%20Oktavianty"> Oke Oktavianty</a> </p> <p class="card-text"><strong>Abstract:</strong></p> It is important to clarify the company’s core technology in product development process to strengthen their power in providing technology that meets the customer requirement. QFD method is adopted to clarify the core technology through identifying the high element technologies that are related to the voice of customer, and offer the most delightful features for customer. AHP is used to determine the importance of evaluating factors. A case study was conducted by using this approach in Japan’s Monozukuri Company (so called manufacturing company) to clarify their core technology based on customer requirements. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=core%20technology" title="core technology">core technology</a>, <a href="https://publications.waset.org/abstracts/search?q=QFD" title=" QFD"> QFD</a>, <a href="https://publications.waset.org/abstracts/search?q=voices%20of%20customer" title=" voices of customer"> voices of customer</a>, <a href="https://publications.waset.org/abstracts/search?q=analysis%20procedure" title=" analysis procedure"> analysis procedure</a> </p> <a href="https://publications.waset.org/abstracts/64768/study-on-clarification-of-the-core-technology-in-a-monozukuri-company" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/64768.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">386</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2100</span> Correlation of Urinary Waxy Casts with Renal Pathology</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Muner%20M.%20B.%20Mohamed">Muner M. B. Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Vipin%20Varghese"> Vipin Varghese</a>, <a href="https://publications.waset.org/abstracts/search?q=Dustin%20Chalmers"> Dustin Chalmers</a>, <a href="https://publications.waset.org/abstracts/search?q=Khalid%20M.%20G.%20Mohammed"> Khalid M. G. Mohammed</a>, <a href="https://publications.waset.org/abstracts/search?q=Juan%20Carlos%20Q.%20Velez"> Juan Carlos Q. Velez</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Urinary waxy casts (uWxC) are traditionally described in textbooks as indicative of chronic renal parenchymal disease. However, data supporting this contention is lacking. uWxC can be seen in the context of various renal syndromes, including acute kidney injury, chronic kidney disease, rapidly progressive glomerulonephritis (GN), and nephrotic syndrome. Thus, we investigated the correlation between the identification of uWxC and renal pathological findings. Methods: We prospectively collected data of patients seen in nephrology consultation with a urine specimen subjected to the microscopic examination of the urinary sediment (MicrExUrSed) over a 3-year period. Within this cohort, we identified cases in which a kidney biopsy was concomitantly performed. We assessed the association of uWxC with glomerular or tubular pathology and with chronicity [interstitial fibrosis and tubular atrophy (IFTA) and glomerular obsolescence (GO)]. Results: Among 683 patients with MicrExUrSed,103 (15%) underwent kidney biopsy and were included. The mean age was 55 years, 51% women, 50% white, and 38% self-identified black. Median serum creatinine was 3.2 (0-7-15.6) mg/dL and not significantly different between those with and without uWxC (4.7 vs 3.8 mg/dL, p=0.13). uWxC was identified in 35 (34%) cases. A glomerulopathy was diagnosed in 79 (77%). Among those with uWxC (n=35), a glomerulopathy was more likely to be found with concomitant acute tubular injury (ATI) than without ATI (57% vs. 23%, p=0.0006), whereas among those without uWxC, glomerulopathies were found with or without concomitant ATI with similar frequency (41% vs. 34%, p=0.48). Overall (n=103), more patients with uWxC had ≥ 20% IFTA compared to those without uWxC (74% vs 51%, p=0.03). Among those with glomerulopathy (n=79), more patients with uWxC had ≥ 20% IFTA compared to those without uWxC (89% vs. 56%, p=0.004). uWxC did not correlate with GO. Conclusion: Identification of uWxC denotes a greater likelihood of finding evidence of ATI superimposed with a glomerulopathy rather than finding an isolated glomerular lesion. uWxC is associated with a greater probability of finding ≥ 20% IFTA in a kidney biopsy specimen, particularly in those with a glomerular pathology. This observation may help clinicians weigh on the suitability of a kidney biopsy when chronicity or coexistence of ATI is in question. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=waxy%20cast" title="waxy cast">waxy cast</a>, <a href="https://publications.waset.org/abstracts/search?q=kidney%20biopsy" title=" kidney biopsy"> kidney biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=acute%20tubular%20injury" title=" acute tubular injury"> acute tubular injury</a>, <a href="https://publications.waset.org/abstracts/search?q=glomerulopathy" title=" glomerulopathy"> glomerulopathy</a> </p> <a href="https://publications.waset.org/abstracts/158781/correlation-of-urinary-waxy-casts-with-renal-pathology" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/158781.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right 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