CINXE.COM

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Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways & Lineage-specific Markers </a> </li> <input type="hidden" name="pw_parent" value="stem-cells"> </form> <form id="pathways_hematopoietic_stem_cell_differentiation_pathways__lineage-specific_markers" action="/pathways/hematopoietic-stem-cell-differentiation-pathways-lineage-specific-markers" method="post"> <li class=""> <a href="/pathways/hematopoietic-stem-cell-differentiation-pathways-lineage-specific-markers" class="pathway_link" data-form="pathways_hematopoietic_stem_cell_differentiation_pathways__lineage-specific_markers"> Hematopoietic Stem Cell Differentiation Pathways & Lineage-specific Markers </a> </li> <input type="hidden" name="pw_parent" value="stem-cells"> </form> <form id="pathways_mesenchymal_stem_cell_differentiation_pathways__lineage-specific_markers" action="/pathways/mesenchymal-stem-cell-differentiation-pathways-lineage-specific-markers" method="post"> <li class="active"> <a href="/pathways/mesenchymal-stem-cell-differentiation-pathways-lineage-specific-markers" class="pathway_link" data-form="pathways_mesenchymal_stem_cell_differentiation_pathways__lineage-specific_markers"> Mesenchymal Stem Cell Differentiation Pathways & Lineage-specific Markers </a> </li> <input type="hidden" name="pw_parent" value="stem-cells"> </form> <form id="pathways_neural_stem_cell_differentiation_pathways__lineage-specific_markers" action="/pathways/neural-stem-cell-differentiation-pathways-lineage-specific-markers" method="post"> <li class=""> <a href="/pathways/neural-stem-cell-differentiation-pathways-lineage-specific-markers" class="pathway_link" data-form="pathways_neural_stem_cell_differentiation_pathways__lineage-specific_markers"> Neural Stem Cell Differentiation Pathways & Lineage-specific Markers </a> </li> <input type="hidden" name="pw_parent" value="stem-cells"> </form> </ul> </li> <li class="pathways-li "> <form id="pathways_ubiquitin_related_modifiers__pathways" action="/pathways/ubiquitin-related-modifiers-and-pathways" method="post"> <a href="/pathways/ubiquitin-related-modifiers-and-pathways" data-form="pathways_ubiquitin_related_modifiers__pathways" class="pathway_link"> <span class="icon-"> Ubiquitin, Related Modifiers, & Pathways </span> </a> <input type="hidden" name="pw_parent" value="ubiquitin-related-modifiers-and-pathways"> </form> </li> </ul> </div> </div> </div> </div> </div> <div class="pw_right col-xs-12 col-sm-8 col-md-9"> <div class="search_mobile_buttons"> <div class="pw_menu_toggle btn btn-tertiary">Show Categories</div> </div> <div class="pw_header"> <h1>Mesenchymal Stem Cell Differentiation Pathways & Lineage-specific Markers</h1> <p id="pw-intro-txt">Click on a cell type below to view a subset of molecules used as markers for the identification of that cell type.<br></p> <div id="pw-con" data-mapname="" data-primary_segment="msc_all"> <div id="pw-main-nav-wrapper"> <div class="row"> <div id="pw-button-nav-top" class="col-xs-12 col-sm-12"> <div class="row"> <div id="pw-button-nav"> <div class="dropdown col-xs-12 col-sm-6 col-md-4"> <button class="btn-pw" type="button" data-toggle="dropup">Explore Pathways<span class="caret"></span></button> <ul id="pathwaynav" class="dropdown-content" style="clear:both"><li data-segment="MSC_White_Adipocytes" data-background_image="MSC_White_Adipocytes.png" data-pathway_segment="Pathway_MSC_White_Adipocytes" class="pw_rdblue_sm pw_sm_btn"><span>White Adipocytes</span></li> <li data-segment="MSC_Brown_Adipocytes" data-background_image="MSC_Brown_Adipocytes.png" data-pathway_segment="Pathway_MSC_Brown_Adipocytes" class="pw_rdblue_sm pw_sm_btn"><span>Brown Adipocytes</span></li> <li data-segment="MSC_Myocytes" data-background_image="MSC_Myocytes.png" data-pathway_segment="Pathway_MSC_Myocytes" class="pw_rdblue_sm pw_sm_btn"><span>Myocytes</span></li> <li data-segment="MSC_Chondrocytes" data-background_image="MSC_Chondrocytes.png" data-pathway_segment="Pathway_MSC_Chondrocytes" class="pw_rdblue_sm pw_sm_btn"><span>Chondrocytes</span></li> <li data-segment="MSC_Osteocytes" data-background_image="MSC_Osteocytes.png" data-pathway_segment="Pathway_MSC_Osteocytes" class="pw_rdblue_sm pw_sm_btn"><span>Osteocytes</span></li> <li data-segment="MSC_All" data-background_image="MSC_markers_all.png" data-pathway_segment="Pathway_MSC_All" class="pw_sm_btn-active"><span>View聽Full聽Pathway</span></li> </ul> </div> </div> <div class="col-xs-12 col-sm-6 col-md-5" > <div id="pw-nav-subtitle"> Mesenchymal Stem Cell Differentiation Pathways & Lineage-specific Markers </div> </div> <div id="pw-print-button-col" class="col-xs-12 col-sm-6 col-md-3" > <a href="#print-copy-form" id="btn-get-print-copy" class="btn btn-primary"><img class="btn-icon" src="https://resources.rndsystems.com/images/Pathways/icons/icon-image.svg"/> Get Print Copy</a> </div> </div> </div> </div> </div> <div id="pw-map"> <div id="pw-maps"> <div id="el1_gry" class="msc_all msc_white_adipocytes msc_brown_adipocytes msc_myocytes msc_chondrocytes msc_osteocytes pw-sprite el-gray1 pw-gray" style="top:17px;left:333px;"> </div> <div id="el1_off" data-id="1" data-set="MesenchymalStemCells2" data-type="" class="msc_all msc_white_adipocytes msc_brown_adipocytes msc_myocytes msc_chondrocytes msc_osteocytes pw-sprite el-off1" style="top:17px;left:333px;"> </div> <div id="el1_ct" class="pw-tooltip" data-id="1"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/alcam-cd166">ALCAM/CD166</a><br> <a target="_blank" href="/target/5-nucleotidase-cd73">5'-Nucleotidase/CD73</a><br> <a target="_blank" href="/target/cd90-thy1">CD90/Thy1</a><br> <a target="_blank" href="/target/endoglin-cd105">Endoglin/CD105</a><br> <a target="_blank" href="/target/mcam-cd146">MCAM/CD146</a><br> <a target="_blank" href="/target/integrin-beta-1-cd29">Integrin beta 1/CD29</a><br> <a target="_blank" href="/target/sca-1-ly6">Sca-1/Ly6</a><br> <a target="_blank" href="/target/vcam-1-cd106">VCAM-1/CD106</a><br> <a target="_blank" href="/target/cd44">CD44</a><br> <a target="_blank" href="/target/stro-1">STRO-1</a><br> <a target="_blank" href="/target/cd117-c-kit">CD117/c-kit</a><br> <a target="_blank" href="/target/ngf-r-tnfrsf16">NGF R/TNFRSF16</a><br> <a target="_blank" href="/target/cd45">CD45</a><br> <a target="_blank" href="/target/cd34">CD34</a><br> <a target="_blank" href="/target/cd79a">CD79A</a><br> <a target="_blank" href="/target/hla-class-i">HLA Class I</a><br> <a target="_blank" href="/target/cd14">CD14</a><br> <a target="_blank" href="/target/cd19">CD19</a><br> <a target="_blank" href="/target/integrin-alpha-m-cd11b">Integrin alpha M/CD11b</a><br> </div> </div> <div id="el2_gry" class="msc_all msc_white_adipocytes msc_brown_adipocytes msc_myocytes msc_chondrocytes msc_osteocytes pw-label pw-right el-gray2 pw-gray" style="top:33px;left:257px;"> Mesenchymal<br>Stem Cells </div> <div id="el2_off" data-id="2" data-set="MesenchymalStemCells2" data-type="No Products Click" class="msc_all msc_white_adipocytes msc_brown_adipocytes msc_myocytes msc_chondrocytes msc_osteocytes pw-label pw-right el-off2" style="top:33px;left:257px;"> Mesenchymal<br>Stem Cells</div> <div id="el2_ct" class="pw-tooltip" data-id="2"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/endoglin-cd105">Endoglin/CD105</a><br> <a target="_blank" href="/target/mcam-cd146">MCAM/CD146</a><br> <a target="_blank" href="/target/cd90-thy1">CD90/Thy1</a><br> <a target="_blank" href="/target/integrin-beta-1-cd29">Integrin beta 1/CD29</a><br> <a target="_blank" href="/target/sca-1-ly6">Sca-1/Ly6</a><br> <a target="_blank" href="/target/5-nucleotidase-cd73">5'-Nucleotidase/CD73</a><br> <a target="_blank" href="/target/alcam-cd166">ALCAM/CD166</a><br> <a target="_blank" href="/target/vcam-1-cd106">VCAM-1/CD106</a><br> <a target="_blank" href="/target/cd44">CD44</a><br> <a target="_blank" href="/target/stro-1">STRO-1</a><br> <a target="_blank" href="/target/cd117-c-kit">CD117/c-kit</a><br> <a target="_blank" href="/target/ngf-r-tnfrsf16">NGF R/TNFRSF16</a><br> <a target="_blank" href="/target/cd45">CD45</a><br> <a target="_blank" href="/target/cd34">CD34</a><br> <a target="_blank" href="/target/cd79a">CD79A</a><br> <a target="_blank" href="/target/hla-class-i">HLA Class I</a><br> <a target="_blank" href="/target/cd14">CD14</a><br> <a target="_blank" href="/target/cd19">CD19</a><br> <a target="_blank" href="/target/integrin-alpha-m-cd11b">Integrin alpha M/CD11b</a><br> </div> </div> <div id="el3_gry" class="msc_all msc_white_adipocytes pw-label el-gray3 pw-gray" style="top:52px;left:157px;"> Noggin </div> <div id="el3_off" data-id="3" data-set="Noggin" data-type="No Products Click" class="msc_all msc_white_adipocytes pw-label el-off3" style="top:52px;left:157px;"> Noggin</div> <div id="el3_ct" class="pw-tooltip" data-id="3"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/noggin">Noggin</a><br> </div> </div> <div id="el4_gry" class="msc_all msc_white_adipocytes pw-label el-gray4 pw-gray" style="top:96px;left:182px;"> BMP-2, 4 </div> <div id="el4_off" data-id="4" data-set="BMP-24" data-type="No Products Click" class="msc_all msc_white_adipocytes pw-label el-off4" style="top:96px;left:182px;"> BMP-2, 4</div> <div id="el4_ct" class="pw-tooltip" data-id="4"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bmp-2">BMP-2</a><br> <a target="_blank" href="/target/bmp-4">BMP-4</a><br> </div> </div> <div id="el5_gry" class="msc_all msc_white_adipocytes pw-label el-gray5 pw-gray" style="top:112px;left:182px;"> Insulin </div> <div id="el5_off" data-id="5" data-set="Insulin" data-type="No Products Click" class="msc_all msc_white_adipocytes pw-label el-off5" style="top:112px;left:182px;"> Insulin</div> <div id="el5_ct" class="pw-tooltip" data-id="5"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/insulin">Insulin</a><br> </div> </div> <div id="el6_gry" class="msc_all msc_white_adipocytes pw-label el-gray6 pw-gray" style="top:128px;left:182px;"> Wnt-5b </div> <div id="el6_off" data-id="6" data-set="Wnt-5b" data-type="No Products Click" class="msc_all msc_white_adipocytes pw-label el-off6" style="top:128px;left:182px;"> Wnt-5b</div> <div id="el6_ct" class="pw-tooltip" data-id="6"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/wnt-5b">Wnt-5b</a><br> </div> </div> <div id="el7_gry" class="msc_all msc_white_adipocytes pw-label el-gray7 pw-gray" style="top:144px;left:182px;"> Adipogenesis<br>Induction<br>Media </div> <div id="el7_off" data-id="7" data-set="Wnt-5b" data-type="No Products Click" class="msc_all msc_white_adipocytes pw-label el-off7" style="top:144px;left:182px;"> Adipogenesis<br>Induction<br>Media</div> <div id="el7_ct" class="pw-tooltip" data-id="7"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/wnt-5b">Wnt-5b</a><br> </div> </div> <div id="el8_gry" class="msc_all msc_white_adipocytes pw-sprite el-gray8 pw-gray" style="top:110px;left:86px;"> </div> <div id="el8_off" data-id="8" data-set="WhitePre-Adipocyte7" data-type="No Products Click" class="msc_all msc_white_adipocytes pw-sprite el-off8" style="top:110px;left:86px;"> </div> <div id="el8_ct" class="pw-tooltip" data-id="8"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ppar-gamma-nr1c3">PPAR gamma/NR1C3</a><br> <a target="_blank" href="/target/cebp-alpha">CEBP alpha</a><br> <a target="_blank" href="/search?keywords=1126/100">Dexamethasone</a><br> </div> </div> <div id="el9_gry" class="msc_all msc_white_adipocytes pw-label pw-center el-gray9 pw-gray" style="top:121px;left:78px;"> White<br>Pre-Adipocytes </div> <div id="el9_off" data-id="9" data-set="WhitePre-Adipocyte7" data-type="No Products Click" class="msc_all msc_white_adipocytes pw-label pw-center el-off9" style="top:121px;left:78px;"> White<br>Pre-Adipocytes</div> <div id="el9_ct" class="pw-tooltip" data-id="9"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ppar-gamma-nr1c3">PPAR gamma/NR1C3</a><br> <a target="_blank" href="/target/cebp-alpha">CEBP alpha</a><br> <a target="_blank" href="/search?keywords=1126/100">Dexamethasone</a><br> </div> </div> <div id="el10_gry" class="msc_all msc_white_adipocytes pw-label el-gray10 pw-gray" style="top:196px;left:108px;"> BMP-2, 4 </div> <div id="el10_off" data-id="10" data-set="BMP-244" data-type="No Products Click" class="msc_all msc_white_adipocytes pw-label el-off10" style="top:196px;left:108px;"> BMP-2, 4</div> <div id="el10_ct" class="pw-tooltip" data-id="10"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bmp-2">BMP-2</a><br> <a target="_blank" href="/target/bmp-4">BMP-4</a><br> </div> </div> <div id="el11_gry" class="msc_all msc_white_adipocytes pw-label el-gray11 pw-gray" style="top:212px;left:108px;"> Insulin </div> <div id="el11_off" data-id="11" data-set="Insulin" data-type="No Products Click" class="msc_all msc_white_adipocytes pw-label el-off11" style="top:212px;left:108px;"> Insulin</div> <div id="el11_ct" class="pw-tooltip" data-id="11"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/insulin">Insulin</a><br> </div> </div> <div id="el12_gry" class="msc_all msc_white_adipocytes pw-label el-gray12 pw-gray" style="top:222px;left:48px;"> Noggin </div> <div id="el12_off" data-id="12" data-set="Noggin" data-type="No Products Click" class="msc_all msc_white_adipocytes pw-label el-off12" style="top:222px;left:48px;"> Noggin</div> <div id="el12_ct" class="pw-tooltip" data-id="12"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/noggin">Noggin</a><br> </div> </div> <div id="el13_gry" class="msc_all msc_white_adipocytes pw-sprite el-gray13 pw-gray" style="top:273px;left:89px;"> </div> <div id="el13_off" data-id="13" data-set="WhiteAdipocyte11" data-type="No Products Click" class="msc_all msc_white_adipocytes pw-sprite el-off13" style="top:273px;left:89px;"> </div> <div id="el13_ct" class="pw-tooltip" data-id="13"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lipoprotein-lipase-lpl">Lipoprotein Lipase/LPL</a><br> <a target="_blank" href="/target/glut4">Glut4</a><br> <a target="_blank" href="/target/ppar-gamma-nr1c3">PPAR gamma/NR1C3</a><br> <a target="_blank" href="/target/adiponectin-acrp30">Adiponectin/Acrp30</a><br> <a target="_blank" href="/target/leptin-ob">Leptin/OB</a><br> <a target="_blank" href="/target/fabp4-a-fabp">FABP4/A-FABP</a><br> </div> </div> <div id="el14_gry" class="msc_all msc_white_adipocytes pw-label pw-center el-gray14 pw-gray" style="top:283px;left:89px;"> White<br>Adipocytes </div> <div id="el14_off" data-id="14" data-set="WhiteAdipocyte11" data-type="No Products Click" class="msc_all msc_white_adipocytes pw-label pw-center el-off14" style="top:283px;left:89px;"> White<br>Adipocytes</div> <div id="el14_ct" class="pw-tooltip" data-id="14"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lipoprotein-lipase-lpl">Lipoprotein Lipase/LPL</a><br> <a target="_blank" href="/target/glut4">Glut4</a><br> <a target="_blank" href="/target/ppar-gamma-nr1c3">PPAR gamma/NR1C3</a><br> <a target="_blank" href="/target/adiponectin-acrp30">Adiponectin/Acrp30</a><br> <a target="_blank" href="/target/leptin-ob">Leptin/OB</a><br> <a target="_blank" href="/target/fabp4-a-fabp">FABP4/A-FABP</a><br> </div> </div> <div id="el15_gry" class="msc_all msc_brown_adipocytes msc_myocytes pw-label el-gray15 pw-gray" style="top:109px;left:283px;"> FGF basic </div> <div id="el15_off" data-id="15" data-set="FGFbasic" data-type="No Products Click" class="msc_all msc_brown_adipocytes msc_myocytes pw-label el-off15" style="top:109px;left:283px;"> FGF basic</div> <div id="el15_ct" class="pw-tooltip" data-id="15"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/fgf-basic">FGF basic</a><br> </div> </div> <div id="el16_gry" class="msc_all msc_brown_adipocytes msc_myocytes pw-label el-gray16 pw-gray" style="top:126px;left:283px;"> TGF-Beta </div> <div id="el16_off" data-id="16" data-set="TGFbeta" data-type="No Products Click" class="msc_all msc_brown_adipocytes msc_myocytes pw-label el-off16" style="top:126px;left:283px;"> TGF-Beta</div> <div id="el16_ct" class="pw-tooltip" data-id="16"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/tgf-beta">TGF-beta</a><br> </div> </div> <div id="el17_gry" class="msc_all msc_brown_adipocytes msc_myocytes pw-sprite el-gray17 pw-gray" style="top:204px;left:229px;"> </div> <div id="el17_off" data-id="17" data-set="MyogenicPrecursor14" data-type="No Products Click" class="msc_all msc_brown_adipocytes msc_myocytes pw-sprite el-off17" style="top:204px;left:229px;"> </div> <div id="el17_ct" class="pw-tooltip" data-id="17"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/integrin-alpha-1-cd49a">Integrin alpha 1/CD49a</a><br> <a target="_blank" href="/target/m-cadherin-cadherin-15">M-Cadherin/Cadherin-15</a><br> <a target="_blank" href="/target/myf-5">MYF-5</a><br> <a target="_blank" href="/target/pax3">Pax3</a><br> <a target="_blank" href="/target/pax7">Pax7</a><br> <a target="_blank" href="/target/myogenin">Myogenin</a><br> <a target="_blank" href="/target/myod">MyoD</a><br> <a target="_blank" href="/search?keywords=3842/50">5-azacytidine</a><br> </div> </div> <div id="el18_gry" class="msc_all msc_brown_adipocytes msc_myocytes pw-label pw-center el-gray18 pw-gray" style="top:210px;left:230px;"> Myogenic<br>Precursors </div> <div id="el18_off" data-id="18" data-set="MyogenicPrecursor14" data-type="No Products Click" class="msc_all msc_brown_adipocytes msc_myocytes pw-label pw-center el-off18" style="top:210px;left:230px;"> Myogenic<br>Precursors</div> <div id="el18_ct" class="pw-tooltip" data-id="18"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/integrin-alpha-1-cd49a">Integrin alpha 1/CD49a</a><br> <a target="_blank" href="/target/m-cadherin-cadherin-15">M-Cadherin/Cadherin-15</a><br> <a target="_blank" href="/target/myf-5">MYF-5</a><br> <a target="_blank" href="/target/pax3">Pax3</a><br> <a target="_blank" href="/target/pax7">Pax7</a><br> <a target="_blank" href="/target/myogenin">Myogenin</a><br> <a target="_blank" href="/target/myod">MyoD</a><br> </div> </div> <div id="el19_gry" class="msc_all msc_brown_adipocytes pw-label el-gray19 pw-gray" style="top:301px;left:193px;"> BMP-7 </div> <div id="el19_off" data-id="19" data-set="BMP-7" data-type="No Products Click" class="msc_all msc_brown_adipocytes pw-label el-off19" style="top:301px;left:193px;"> BMP-7</div> <div id="el19_ct" class="pw-tooltip" data-id="19"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bmp-7">BMP-7</a><br> </div> </div> <div id="el20_gry" class="msc_all msc_brown_adipocytes pw-sprite el-gray20 pw-gray" style="top:367px;left:154px;"> </div> <div id="el20_off" data-id="20" data-set="BrownPre-Adipocyte16" data-type="No Products Click" class="msc_all msc_brown_adipocytes pw-sprite el-off20" style="top:367px;left:154px;"> </div> <div id="el20_ct" class="pw-tooltip" data-id="20"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/integrin-beta-1-cd29">Integrin beta 1/CD29</a><br> <a target="_blank" href="/target/cd34">CD34</a><br> <a target="_blank" href="/target/sca-1-ly6">Sca-1/Ly6</a><br> <a target="_blank" href="/target/ppar-gamma-nr1c3">PPAR gamma/NR1C3</a><br> <a target="_blank" href="/target/cebp-alpha">CEBP alpha</a><br> </div> </div> <div id="el21_gry" class="msc_all msc_brown_adipocytes pw-label pw-center el-gray21 pw-gray" style="top:372px;left:143px;"> Brown<br>Pre-Adipocytes </div> <div id="el21_off" data-id="21" data-set="BrownPre-Adipocyte16" data-type="No Products Click" class="msc_all msc_brown_adipocytes pw-label pw-center el-off21" style="top:372px;left:143px;"> Brown<br>Pre-Adipocytes</div> <div id="el21_ct" class="pw-tooltip" data-id="21"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/integrin-beta-1-cd29">Integrin beta 1/CD29</a><br> <a target="_blank" href="/target/cd34">CD34</a><br> <a target="_blank" href="/target/sca-1-ly6">Sca-1/Ly6</a><br> <a target="_blank" href="/target/ppar-gamma-nr1c3">PPAR gamma/NR1C3</a><br> <a target="_blank" href="/target/cebp-alpha">CEBP alpha</a><br> </div> </div> <div id="el22_gry" class="msc_all msc_brown_adipocytes pw-label el-gray22 pw-gray" style="top:443px;left:109px;"> BMP-7 </div> <div id="el22_off" data-id="22" data-set="BMP-7" data-type="No Products Click" class="msc_all msc_brown_adipocytes pw-label el-off22" style="top:443px;left:109px;"> BMP-7</div> <div id="el22_ct" class="pw-tooltip" data-id="22"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bmp-7">BMP-7</a><br> </div> </div> <div id="el23_gry" class="msc_all msc_brown_adipocytes pw-sprite el-gray23 pw-gray" style="top:507px;left:102px;"> </div> <div id="el23_off" data-id="23" data-set="BrownAdipocyte18" data-type="No Products Click" class="msc_all msc_brown_adipocytes pw-sprite el-off23" style="top:507px;left:102px;"> </div> <div id="el23_ct" class="pw-tooltip" data-id="23"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/fabp4-a-fabp">FABP4/A-FABP</a><br> <a target="_blank" href="/target/cebp-alpha">CEBP alpha</a><br> <a target="_blank" href="/target/ppar-gamma-nr1c3">PPAR gamma/NR1C3</a><br> <a target="_blank" href="/target/pgc1-alpha">PGC1 alpha</a><br> <a target="_blank" href="/target/ucp1">UCP1</a><br> </div> </div> <div id="el24_gry" class="msc_all msc_brown_adipocytes pw-label pw-center el-gray24 pw-gray" style="top:517px;left:107px;"> Brown<br>Adipocytes </div> <div id="el24_off" data-id="24" data-set="BrownAdipocyte18" data-type="No Products Click" class="msc_all msc_brown_adipocytes pw-label pw-center el-off24" style="top:517px;left:107px;"> Brown<br>Adipocytes</div> <div id="el24_ct" class="pw-tooltip" data-id="24"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/fabp4-a-fabp">FABP4/A-FABP</a><br> <a target="_blank" href="/target/cebp-alpha">CEBP alpha</a><br> <a target="_blank" href="/target/ppar-gamma-nr1c3">PPAR gamma/NR1C3</a><br> <a target="_blank" href="/target/pgc1-alpha">PGC1 alpha</a><br> <a target="_blank" href="/target/ucp1">UCP1</a><br> </div> </div> <div id="el25_gry" class="msc_all msc_myocytes pw-label el-gray25 pw-gray" style="top:303px;left:280px;"> FGF basic </div> <div id="el25_off" data-id="25" data-set="FGFbasic" data-type="No Products Click" class="msc_all msc_myocytes pw-label el-off25" style="top:303px;left:280px;"> FGF basic</div> <div id="el25_ct" class="pw-tooltip" data-id="25"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/fgf-basic">FGF basic</a><br> </div> </div> <div id="el26_gry" class="msc_all msc_myocytes pw-label el-gray26 pw-gray" style="top:321px;left:280px;"> TGF-Beta </div> <div id="el26_off" data-id="26" data-set="TGF-beta" data-type="No Products Click" class="msc_all msc_myocytes pw-label el-off26" style="top:321px;left:280px;"> TGF-Beta</div> <div id="el26_ct" class="pw-tooltip" data-id="26"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/tgf-beta">TGF-beta</a><br> </div> </div> <div id="el27_gry" class="msc_all msc_myocytes pw-sprite el-gray27 pw-gray" style="top:368px;left:259px;"> </div> <div id="el27_off" data-id="27" data-set="Myoblast21" data-type="No Products Click" class="msc_all msc_myocytes pw-sprite el-off27" style="top:368px;left:259px;"> </div> <div id="el27_ct" class="pw-tooltip" data-id="27"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/integrin-alpha-1-cd49a">Integrin alpha 1/CD49a</a><br> <a target="_blank" href="/target/m-cadherin-cadherin-15">M-Cadherin/Cadherin-15</a><br> <a target="_blank" href="/target/myf-5">MYF-5</a><br> <a target="_blank" href="/target/pax3">Pax3</a><br> <a target="_blank" href="/target/pax7">Pax7</a><br> <a target="_blank" href="/target/myod">MyoD</a><br> <a target="_blank" href="/target/myogenin">Myogenin</a><br> </div> </div> <div id="el28_gry" class="msc_all msc_myocytes pw-label el-gray28 pw-gray" style="top:392px;left:278px;"> Myoblasts </div> <div id="el28_off" data-id="28" data-set="Myoblast21" data-type="No Products Click" class="msc_all msc_myocytes pw-label el-off28" style="top:392px;left:278px;"> Myoblasts</div> <div id="el28_ct" class="pw-tooltip" data-id="28"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/integrin-alpha-1-cd49a">Integrin alpha 1/CD49a</a><br> <a target="_blank" href="/target/m-cadherin-cadherin-15">M-Cadherin/Cadherin-15</a><br> <a target="_blank" href="/target/myf-5">MYF-5</a><br> <a target="_blank" href="/target/pax3">Pax3</a><br> <a target="_blank" href="/target/pax7">Pax7</a><br> <a target="_blank" href="/target/myod">MyoD</a><br> <a target="_blank" href="/target/myogenin">Myogenin</a><br> </div> </div> <div id="el29_gry" class="msc_all msc_myocytes pw-label el-gray29 pw-gray" style="top:467px;left:220px;"> PDGF-BB </div> <div id="el29_off" data-id="29" data-set="PDGF-BB" data-type="No Products Click" class="msc_all msc_myocytes pw-label el-off29" style="top:467px;left:220px;"> PDGF-BB</div> <div id="el29_ct" class="pw-tooltip" data-id="29"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pdgf-bb">PDGF-BB</a><br> </div> </div> <div id="el30_gry" class="msc_all msc_myocytes pw-label el-gray30 pw-gray" style="top:482px;left:220px;"> Wnt-4, 7b </div> <div id="el30_off" data-id="30" data-set="Wnt47b" data-type="No Products Click" class="msc_all msc_myocytes pw-label el-off30" style="top:482px;left:220px;"> Wnt-4, 7b</div> <div id="el30_ct" class="pw-tooltip" data-id="30"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/wnt-4">Wnt-4</a><br> <a target="_blank" href="/target/wnt-7b">Wnt-7b</a><br> </div> </div> <div id="el31_gry" class="msc_all msc_myocytes pw-sprite el-gray31 pw-gray" style="top:555px;left:202px;"> </div> <div id="el31_off" data-id="31" data-set="SkeletalMuscle24" data-type="No Products Click" class="msc_all msc_myocytes pw-sprite el-off31" style="top:555px;left:202px;"> </div> <div id="el31_ct" class="pw-tooltip" data-id="31"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/mcam-cd146">MCAM/CD146</a><br> <a target="_blank" href="/search?keywords=calpain">mu-Calpain</a><br> <a target="_blank" href="/target/integrin-alpha-7-beta-1">Integrin alpha 7 beta 1</a><br> <a target="_blank" href="/target/myod">MyoD</a><br> <a target="_blank" href="/target/fabp3-h-fabp">FABP3/H-FABP</a><br> <a target="_blank" href="/target/myogenin">Myogenin</a><br> <a target="_blank" href="/target/troponin-i">Troponin I</a><br> <a target="_blank" href="/search?keywords=0695">Retinoic Acid</a><br> </div> </div> <div id="el32_gry" class="msc_all msc_myocytes pw-label pw-center el-gray32 pw-gray" style="top:556px;left:218px;"> Skeletal<br>Muscle </div> <div id="el32_off" data-id="32" data-set="SkeletalMuscle24" data-type="No Products Click" class="msc_all msc_myocytes pw-label pw-center el-off32" style="top:556px;left:218px;"> Skeletal<br>Muscle</div> <div id="el32_ct" class="pw-tooltip" data-id="32"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/mcam-cd146">MCAM/CD146</a><br> <a target="_blank" href="/search?keywords=calpain">mu-Calpain</a><br> <a target="_blank" href="/target/integrin-alpha-7-beta-1">Integrin alpha 7 beta 1</a><br> <a target="_blank" href="/target/myod">MyoD</a><br> <a target="_blank" href="/target/fabp3-h-fabp">FABP3/H-FABP</a><br> <a target="_blank" href="/target/myogenin">Myogenin</a><br> <a target="_blank" href="/target/troponin-i">Troponin I</a><br> <a target="_blank" href="/search?keywords=0695">Retinoic Acid</a><br> </div> </div> <div id="el33_gry" class="msc_all msc_myocytes pw-label el-gray33 pw-gray" style="top:495px;left:309px;"> BMP-4 </div> <div id="el33_off" data-id="33" data-set="BMP-4" data-type="No Products Click" class="msc_all msc_myocytes pw-label el-off33" style="top:495px;left:309px;"> BMP-4</div> <div id="el33_ct" class="pw-tooltip" data-id="33"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bmp-4">BMP-4</a><br> </div> </div> <div id="el34_gry" class="msc_all msc_myocytes pw-label el-gray34 pw-gray" style="top:529px;left:309px;"> FGF basic </div> <div id="el34_off" data-id="34" data-set="FGFbasic" data-type="No Products Click" class="msc_all msc_myocytes pw-label el-off34" style="top:529px;left:309px;"> FGF basic</div> <div id="el34_ct" class="pw-tooltip" data-id="34"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/fgf-basic">FGF basic</a><br> </div> </div> <div id="el35_gry" class="msc_all msc_myocytes pw-label el-gray35 pw-gray" style="top:512px;left:309px;"> FGF-4, 8 </div> <div id="el35_off" data-id="35" data-set="FGF488" data-type="No Products Click" class="msc_all msc_myocytes pw-label el-off35" style="top:512px;left:309px;"> FGF-4, 8</div> <div id="el35_ct" class="pw-tooltip" data-id="35"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/fgf-4">FGF-4</a><br> <a target="_blank" href="/target/fgf-8">FGF-8</a><br> </div> </div> <div id="el36_gry" class="msc_all msc_myocytes pw-sprite el-gray36 pw-gray" style="top:584px;left:269px;"> </div> <div id="el36_off" data-id="36" data-set="CardiacMuscle28" data-type="No Products Click" class="msc_all msc_myocytes pw-sprite el-off36" style="top:584px;left:269px;"> </div> <div id="el36_ct" class="pw-tooltip" data-id="36"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cripto">Cripto</a><br> <a target="_blank" href="/target/desmin">Desmin</a><br> <a target="_blank" href="/target/connexin-43-gja1">Connexin 43/GJA1</a><br> <a target="_blank" href="/target/gata-4">GATA-4</a><br> <a target="_blank" href="/target/nkx2-5">NKX2.5</a><br> <a target="_blank" href="/target/tbx5">TBX5</a><br> <a target="_blank" href="/target/mef2c">MEF2C</a><br> <a target="_blank" href="/target/troponin-t">Troponin T</a><br> <a target="_blank" href="/target/troponin-i">Troponin I</a><br> <a target="_blank" href="/target/fabp3-h-fabp">FABP3/H-FABP</a><br> <a target="_blank" href="/target/myosin-heavy-chain">Myosin Heavy Chain</a><br> <a target="_blank" href="/search?keywords=3842/50">5-azacytidine</a><br> <a target="_blank" href="/search?keywords=1158/5">Angiotensin II</a><br> </div> </div> <div id="el37_gry" class="msc_all msc_myocytes pw-label pw-center el-gray37 pw-gray" style="top:605px;left:282px;"> Cardiac<br>Muscle </div> <div id="el37_off" data-id="37" data-set="CardiacMuscle28" data-type="No Products Click" class="msc_all msc_myocytes pw-label pw-center el-off37" style="top:605px;left:282px;"> Cardiac<br>Muscle</div> <div id="el37_ct" class="pw-tooltip" data-id="37"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cripto">Cripto</a><br> <a target="_blank" href="/target/desmin">Desmin</a><br> <a target="_blank" href="/target/connexin-43-gja1">Connexin 43/GJA1</a><br> <a target="_blank" href="/target/gata-4">GATA-4</a><br> <a target="_blank" href="/target/nkx2-5">NKX2.5</a><br> <a target="_blank" href="/target/tbx5">TBX5</a><br> <a target="_blank" href="/target/mef2c">MEF2C</a><br> <a target="_blank" href="/target/troponin-t">Troponin T</a><br> <a target="_blank" href="/target/troponin-i">Troponin I</a><br> <a target="_blank" href="/target/fabp3-h-fabp">FABP3/H-FABP</a><br> <a target="_blank" href="/target/myosin-heavy-chain">Myosin Heavy Chain</a><br> <a target="_blank" href="/search?keywords=3842/50">5-azacytidine</a><br> <a target="_blank" href="/search?keywords=1158/5">Angiotensin II</a><br> </div> </div> <div id="el38_gry" class="msc_all msc_myocytes pw-label el-gray38 pw-gray" style="top:469px;left:362px;"> Wnt-4, 7b </div> <div id="el38_off" data-id="38" data-set="Wnt47bb" data-type="No Products Click" class="msc_all msc_myocytes pw-label el-off38" style="top:469px;left:362px;"> Wnt-4, 7b</div> <div id="el38_ct" class="pw-tooltip" data-id="38"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/wnt-4">Wnt-4</a><br> <a target="_blank" href="/target/wnt-7b">Wnt-7b</a><br> </div> </div> <div id="el39_gry" class="msc_all msc_myocytes pw-sprite el-gray39 pw-gray" style="top:562px;left:374px;"> </div> <div id="el39_off" data-id="39" data-set="SmoothMuscle30" data-type="No Products Click" class="msc_all msc_myocytes pw-sprite el-off39" style="top:562px;left:374px;"> </div> <div id="el39_ct" class="pw-tooltip" data-id="39"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ve-cadherin">VE-Cadherin</a><br> <a target="_blank" href="/target/alpha-smooth-muscle-actin">alpha-Smooth Muscle Actin</a><br> <a target="_blank" href="/target/calponin-1">Calponin 1</a><br> <a target="_blank" href="/search?keywords=0695">Retinoic Acid</a><br> </div> </div> <div id="el40_gry" class="msc_all msc_myocytes pw-label el-gray40 pw-gray" style="top:574px;left:390px;"> Smooth<br>Muscle </div> <div id="el40_off" data-id="40" data-set="SmoothMuscle30" data-type="No Products Click" class="msc_all msc_myocytes pw-label el-off40" style="top:574px;left:390px;"> Smooth<br>Muscle</div> <div id="el40_ct" class="pw-tooltip" data-id="40"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ve-cadherin">VE-Cadherin</a><br> <a target="_blank" href="/target/alpha-smooth-muscle-actin">alpha-Smooth Muscle Actin</a><br> <a target="_blank" href="/target/calponin-1">Calponin 1</a><br> <a target="_blank" href="/search?keywords=0695">Retinoic Acid</a><br> </div> </div> <div id="el41_gry" class="msc_all msc_chondrocytes pw-label el-gray41 pw-gray" style="top:109px;left:415px;"> BMP-5 </div> <div id="el41_off" data-id="41" data-set="BMP-5" data-type="No Products Click" class="msc_all msc_chondrocytes pw-label el-off41" style="top:109px;left:415px;"> BMP-5</div> <div id="el41_ct" class="pw-tooltip" data-id="41"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bmp-5">BMP-5</a><br> </div> </div> <div id="el42_gry" class="msc_all msc_chondrocytes pw-label el-gray42 pw-gray" style="top:142px;left:415px;"> FGF basic </div> <div id="el42_off" data-id="42" data-set="FGFbasic" data-type="No Products Click" class="msc_all msc_chondrocytes pw-label el-off42" style="top:142px;left:415px;"> FGF basic</div> <div id="el42_ct" class="pw-tooltip" data-id="42"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/fgf-basic">FGF basic</a><br> </div> </div> <div id="el43_gry" class="msc_all msc_chondrocytes pw-label el-gray43 pw-gray" style="top:126px;left:415px;"> FGF-4, 8, 10 </div> <div id="el43_off" data-id="43" data-set="FGF4810" data-type="No Products Click" class="msc_all msc_chondrocytes pw-label el-off43" style="top:126px;left:415px;"> FGF-4, 8, 10</div> <div id="el43_ct" class="pw-tooltip" data-id="43"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/fgf-4">FGF-4</a><br> <a target="_blank" href="/target/fgf-8">FGF-8</a><br> <a target="_blank" href="/target/fgf-10">FGF-10</a><br> </div> </div> <div id="el44_gry" class="msc_all msc_chondrocytes pw-label el-gray44 pw-gray" style="top:210px;left:415px;"> TGF-Beta 1, 2 </div> <div id="el44_off" data-id="44" data-set="TGFbeta12" data-type="No Products Click" class="msc_all msc_chondrocytes pw-label el-off44" style="top:210px;left:415px;"> TGF-Beta 1, 2</div> <div id="el44_ct" class="pw-tooltip" data-id="44"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/tgf-beta-1">TGF-beta 1</a><br> <a target="_blank" href="/target/tgf-beta-2">TGF-beta 2</a><br> </div> </div> <div id="el45_gry" class="msc_all msc_chondrocytes pw-label el-gray45 pw-gray" style="top:159px;left:415px;"> N-Cadherin </div> <div id="el45_off" data-id="45" data-set="Ncadherin" data-type="No Products Click" class="msc_all msc_chondrocytes pw-label el-off45" style="top:159px;left:415px;"> N-Cadherin</div> <div id="el45_ct" class="pw-tooltip" data-id="45"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/n-cadherin">N-Cadherin</a><br> </div> </div> <div id="el46_gry" class="msc_all msc_chondrocytes pw-label el-gray46 pw-gray" style="top:177px;left:415px;"> NCAM-1/CD56 </div> <div id="el46_off" data-id="46" data-set="NCAM" data-type="No Products Click" class="msc_all msc_chondrocytes pw-label el-off46" style="top:177px;left:415px;"> NCAM-1/CD56</div> <div id="el46_ct" class="pw-tooltip" data-id="46"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ncam-1-cd56">NCAM-1/CD56</a><br> </div> </div> <div id="el47_gry" class="msc_all msc_chondrocytes pw-label el-gray47 pw-gray" style="top:193px;left:415px;"> Perlecan </div> <div id="el47_off" data-id="47" data-set="Perlecan" data-type="No Products Click" class="msc_all msc_chondrocytes pw-label el-off47" style="top:193px;left:415px;"> Perlecan</div> <div id="el47_ct" class="pw-tooltip" data-id="47"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/endorepellin-perlecan">Endorepellin/Perlecan</a><br> </div> </div> <div id="el48_gry" class="msc_all msc_chondrocytes pw-label el-gray48 pw-gray" style="top:227px;left:415px;"> Veriscan </div> <div id="el48_off" data-id="48" data-set="Veriscan" data-type="No Products Click" class="msc_all msc_chondrocytes pw-label el-off48" style="top:227px;left:415px;"> Veriscan</div> <div id="el48_ct" class="pw-tooltip" data-id="48"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/versican">Versican</a><br> </div> </div> <div id="el49_gry" class="msc_all msc_white_adipocytes pw-label el-gray49 pw-gray" style="top:243px;left:415px;"> Chondrogenesis<br>Induction<br>Media </div> <div id="el49_off" data-id="49" data-set="Wnt-5b" data-type="No Products Click" class="msc_all msc_white_adipocytes pw-label el-off49" style="top:243px;left:415px;"> Chondrogenesis<br>Induction<br>Media</div> <div id="el49_ct" class="pw-tooltip" data-id="49"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/wnt-5b">Wnt-5b</a><br> </div> </div> <div id="el50_gry" class="msc_all msc_chondrocytes pw-sprite el-gray50 pw-gray" style="top:290px;left:484px;"> </div> <div id="el50_off" data-id="50" data-set="CondensingMesenchymalStemCells39" data-type="No Products Click" class="msc_all msc_chondrocytes pw-sprite el-off50" style="top:290px;left:484px;"> </div> <div id="el50_ct" class="pw-tooltip" data-id="50"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/sox9">SOX9</a><br> <a target="_blank" href="/search?keywords=1126/100">Dexamethasone</a><br> <a target="_blank" href="/search?keywords=4055/50">Ascorbic Acid</a><br> <a target="_blank" href="/search?keywords=4513/50">Kartogenin</a><br> <a target="_blank" href="/search?keywords=0695">Retinoic Acid</a><br> </div> </div> <div id="el51_gry" class="msc_all msc_chondrocytes pw-label pw-center el-gray51 pw-gray" style="top:293px;left:472px;"> Condensing<br>Mesenchymal<br>Stem Cells </div> <div id="el51_off" data-id="51" data-set="CondensingMesenchymalStemCells39" data-type="No Products Click" class="msc_all msc_chondrocytes pw-label pw-center el-off51" style="top:293px;left:472px;"> Condensing<br>Mesenchymal<br>Stem Cells</div> <div id="el51_ct" class="pw-tooltip" data-id="51"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/sox9">SOX9</a><br> <a target="_blank" href="/search?keywords=1126/100">Dexamethasone</a><br> <a target="_blank" href="/search?keywords=4055/50">Ascorbic Acid</a><br> <a target="_blank" href="/search?keywords=4513/50">Kartogenin</a><br> <a target="_blank" href="/search?keywords=0695">Retinoic Acid</a><br> </div> </div> <div id="el52_gry" class="msc_all msc_chondrocytes pw-label el-gray52 pw-gray" style="top:370px;left:415px;"> BMP-2, 4, 5, 7 </div> <div id="el52_off" data-id="52" data-set="BMP2457" data-type="No Products Click" class="msc_all msc_chondrocytes pw-label el-off52" style="top:370px;left:415px;"> BMP-2, 4, 5, 7</div> <div id="el52_ct" class="pw-tooltip" data-id="52"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bmp-2">BMP-2</a><br> <a target="_blank" href="/target/bmp-4">BMP-4</a><br> <a target="_blank" href="/target/bmp-5">BMP-5</a><br> <a target="_blank" href="/target/bmp-7">BMP-7</a><br> </div> </div> <div id="el53_gry" class="msc_all msc_chondrocytes pw-label el-gray53 pw-gray" style="top:387px;left:415px;"> GDF-5/BMP-14 </div> <div id="el53_off" data-id="53" data-set="GDF-5BMP-14" data-type="No Products Click" class="msc_all msc_chondrocytes pw-label el-off53" style="top:387px;left:415px;"> GDF-5/BMP-14</div> <div id="el53_ct" class="pw-tooltip" data-id="53"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/gdf-5-bmp-14">GDF-5/BMP-14</a><br> </div> </div> <div id="el54_gry" class="msc_all msc_chondrocytes pw-label el-gray54 pw-gray" style="top:436px;left:415px;"> TGF-Beta 1, 2, 3 </div> <div id="el54_off" data-id="54" data-set="TGFbeta123" data-type="No Products Click" class="msc_all msc_chondrocytes pw-label el-off54" style="top:436px;left:415px;"> TGF-Beta 1, 2, 3</div> <div id="el54_ct" class="pw-tooltip" data-id="54"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/tgf-beta-1">TGF-beta 1</a><br> <a target="_blank" href="/target/tgf-beta-2">TGF-beta 2</a><br> <a target="_blank" href="/target/tgf-beta-3">TGF-beta 3</a><br> </div> </div> <div id="el55_gry" class="msc_all msc_chondrocytes pw-label el-gray55 pw-gray" style="top:403px;left:415px;"> FGF basic </div> <div id="el55_off" data-id="55" data-set="FGFbasic" data-type="No Products Click" class="msc_all msc_chondrocytes pw-label el-off55" style="top:403px;left:415px;"> FGF basic</div> <div id="el55_ct" class="pw-tooltip" data-id="55"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/fgf-basic">FGF basic</a><br> </div> </div> <div id="el56_gry" class="msc_all msc_chondrocytes pw-label el-gray56 pw-gray" style="top:420px;left:415px;"> IGF-1 </div> <div id="el56_off" data-id="56" data-set="IGF-1" data-type="No Products Click" class="msc_all msc_chondrocytes pw-label el-off56" style="top:420px;left:415px;"> IGF-1</div> <div id="el56_ct" class="pw-tooltip" data-id="56"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/igf-i">IGF-I</a><br> </div> </div> <div id="el57_gry" class="msc_all msc_chondrocytes pw-sprite el-gray57 pw-gray" style="top:486px;left:480px;"> </div> <div id="el57_off" data-id="57" data-set="Chondrocyte45" data-type="No Products Click" class="msc_all msc_chondrocytes pw-sprite el-off57" style="top:486px;left:480px;"> </div> <div id="el57_ct" class="pw-tooltip" data-id="57"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd44">CD44</a><br> <a target="_blank" href="/target/cd151">CD151</a><br> <a target="_blank" href="/target/syndecan-1-cd138">Syndecan-1/CD138</a><br> <a target="_blank" href="/target/sox5">SOX5</a><br> <a target="_blank" href="/target/sox6">SOX6</a><br> <a target="_blank" href="/target/sox9">SOX9</a><br> <a target="_blank" href="/target/aggrecan">Aggrecan</a><br> <a target="_blank" href="/target/collagen-ii">Collagen II</a><br> <a target="_blank" href="/target/collagen-iv">Collagen IV</a><br> <a target="_blank" href="/search?keywords=h-89">H-89</a><br> </div> </div> <div id="el58_gry" class="msc_all msc_chondrocytes pw-label el-gray58 pw-gray" style="top:501px;left:472px;"> Chondrocytes </div> <div id="el58_off" data-id="58" data-set="Chondrocyte45" data-type="No Products Click" class="msc_all msc_chondrocytes pw-label el-off58" style="top:501px;left:472px;"> Chondrocytes</div> <div id="el58_ct" class="pw-tooltip" data-id="58"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cd44">CD44</a><br> <a target="_blank" href="/target/cd151">CD151</a><br> <a target="_blank" href="/target/syndecan-1-cd138">Syndecan-1/CD138</a><br> <a target="_blank" href="/target/sox5">SOX5</a><br> <a target="_blank" href="/target/sox6">SOX6</a><br> <a target="_blank" href="/target/sox9">SOX9</a><br> <a target="_blank" href="/target/aggrecan">Aggrecan</a><br> <a target="_blank" href="/target/collagen-ii">Collagen II</a><br> <a target="_blank" href="/target/collagen-iv">Collagen IV</a><br> <a target="_blank" href="/search?keywords=h-89">H-89</a><br> </div> </div> <div id="el59_gry" class="msc_all msc_osteocytes pw-label el-gray59 pw-gray" style="top:111px;left:572px;"> BMP-2 </div> <div id="el59_off" data-id="59" data-set="BMP-2" data-type="No Products Click" class="msc_all msc_osteocytes pw-label el-off59" style="top:111px;left:572px;"> BMP-2</div> <div id="el59_ct" class="pw-tooltip" data-id="59"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bmp-2">BMP-2</a><br> </div> </div> <div id="el60_gry" class="msc_all msc_osteocytes pw-label el-gray60 pw-gray" style="top:128px;left:572px;"> PTH </div> <div id="el60_off" data-id="60" data-set="PTH" data-type="No Products Click" class="msc_all msc_osteocytes pw-label el-off60" style="top:128px;left:572px;"> PTH</div> <div id="el60_ct" class="pw-tooltip" data-id="60"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pth">PTH</a><br> </div> </div> <div id="el61_gry" class="msc_all msc_osteocytes pw-label el-gray61 pw-gray" style="top:144px;left:572px;"> TGF-Beta </div> <div id="el61_off" data-id="61" data-set="TGFbeta" data-type="No Products Click" class="msc_all msc_osteocytes pw-label el-off61" style="top:144px;left:572px;"> TGF-Beta</div> <div id="el61_ct" class="pw-tooltip" data-id="61"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/tgf-beta">TGF-beta</a><br> </div> </div> <div id="el62_gry" class="msc_all msc_osteocytes pw-label el-gray62 pw-gray" style="top:160px;left:572px;"> Wnt-10b </div> <div id="el62_off" data-id="62" data-set="Wnt-10b" data-type="No Products Click" class="msc_all msc_osteocytes pw-label el-off62" style="top:160px;left:572px;"> Wnt-10b</div> <div id="el62_ct" class="pw-tooltip" data-id="62"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/wnt-10b">Wnt-10b</a><br> </div> </div> <div id="el63_gry" class="msc_all msc_white_adipocytes pw-label el-gray63 pw-gray" style="top:176px;left:572px;"> Osteogenesis<br>Induction<br>Media </div> <div id="el63_off" data-id="63" data-set="Wnt-5b" data-type="No Products Click" class="msc_all msc_white_adipocytes pw-label el-off63" style="top:176px;left:572px;"> Osteogenesis<br>Induction<br>Media</div> <div id="el63_ct" class="pw-tooltip" data-id="63"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/wnt-5b">Wnt-5b</a><br> </div> </div> <div id="el64_gry" class="msc_all msc_osteocytes pw-sprite el-gray64 pw-gray" style="top:249px;left:621px;"> </div> <div id="el64_off" data-id="64" data-set="OsteoblastProgenitor50" data-type="No Products Click" class="msc_all msc_osteocytes pw-sprite el-off64" style="top:249px;left:621px;"> </div> <div id="el64_ct" class="pw-tooltip" data-id="64"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/alkaline-phosphatase-alpp-alpi">Alkaline Phosphatase/ALPP/ALPI</a><br> <a target="_blank" href="/target/mcam-cd146">MCAM/CD146</a><br> <a target="_blank" href="/target/runx2-cbfa1">RUNX2/CBFA1</a><br> <a target="_blank" href="/target/osterix-sp7">Osterix/Sp7</a><br> <a target="_blank" href="/target/collagen-i">Collagen I</a><br> <a target="_blank" href="/target/collagen-iI">Collagen II</a><br> <a target="_blank" href="/target/decorin">Decorin</a><br> <a target="_blank" href="/target/thrombopoietin-tpo">Thrombopoietin/Tpo</a><br> <a target="_blank" href="/search?keywords=1126/100">Dexamethasone</a><br> <a target="_blank" href="/search?keywords=2840/50">AICAR</a><br> <a target="_blank" href="/search?keywords=GSA 10">GSA 10</a><br> <a target="_blank" href="/search?keywords=PURMORPHAMINE">Purmorphamine</a><br> <a target="_blank" href="/search?keywords=SP 600125">SP 600125</a><br> </div> </div> <div id="el65_gry" class="msc_all msc_osteocytes pw-label pw-center el-gray65 pw-gray" style="top:258px;left:628px;"> Osteoblast<br>Progenitors </div> <div id="el65_off" data-id="65" data-set="OsteoblastProgenitor50" data-type="No Products Click" class="msc_all msc_osteocytes pw-label pw-center el-off65" style="top:258px;left:628px;"> Osteoblast<br>Progenitors</div> <div id="el65_ct" class="pw-tooltip" data-id="65"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/alkaline-phosphatase-alpp-alpi">Alkaline Phosphatase/ALPP/ALPI</a><br> <a target="_blank" href="/target/mcam-cd146">MCAM/CD146</a><br> <a target="_blank" href="/target/runx2-cbfa1">RUNX2/CBFA1</a><br> <a target="_blank" href="/target/osterix-sp7">Osterix/Sp7</a><br> <a target="_blank" href="/target/collagen-i">Collagen I</a><br> <a target="_blank" href="/target/collagen-iI">Collagen II</a><br> <a target="_blank" href="/target/decorin">Decorin</a><br> <a target="_blank" href="/target/thrombopoietin-tpo">Thrombopoietin/Tpo</a><br> <a target="_blank" href="/search?keywords=1126/100">Dexamethasone</a><br> <a target="_blank" href="/search?keywords=2840/50">AICAR</a><br> <a target="_blank" href="/search?keywords=GSA 10">GSA 10</a><br> <a target="_blank" href="/search?keywords=PURMORPHAMINE">Purmorphamine</a><br> <a target="_blank" href="/search?keywords=SP 600125">SP 600125</a><br> </div> </div> <div id="el66_gry" class="msc_all msc_osteocytes pw-label el-gray66 pw-gray" style="top:332px;left:591px;"> BMP-2, 4, 6 </div> <div id="el66_off" data-id="66" data-set="BMP246" data-type="No Products Click" class="msc_all msc_osteocytes pw-label el-off66" style="top:332px;left:591px;"> BMP-2, 4, 6</div> <div id="el66_ct" class="pw-tooltip" data-id="66"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bmp-2">BMP-2</a><br> <a target="_blank" href="/target/bmp-4">BMP-4</a><br> <a target="_blank" href="/target/bmp-6">BMP-6</a><br> </div> </div> <div id="el67_gry" class="msc_all msc_osteocytes pw-label el-gray67 pw-gray" style="top:384px;left:591px;"> PTH </div> <div id="el67_off" data-id="67" data-set="PTH" data-type="No Products Click" class="msc_all msc_osteocytes pw-label el-off67" style="top:384px;left:591px;"> PTH</div> <div id="el67_ct" class="pw-tooltip" data-id="67"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pth">PTH</a><br> </div> </div> <div id="el68_gry" class="msc_all msc_osteocytes pw-label el-gray68 pw-gray" style="top:349px;left:591px;"> FGF basic </div> <div id="el68_off" data-id="68" data-set="FGFbasic" data-type="No Products Click" class="msc_all msc_osteocytes pw-label el-off68" style="top:349px;left:591px;"> FGF basic</div> <div id="el68_ct" class="pw-tooltip" data-id="68"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/fgf-basic">FGF basic</a><br> </div> </div> <div id="el69_gry" class="msc_all msc_osteocytes pw-label el-gray69 pw-gray" style="top:367px;left:591px;"> IGF-1 </div> <div id="el69_off" data-id="69" data-set="IGF-1" data-type="No Products Click" class="msc_all msc_osteocytes pw-label el-off69" style="top:367px;left:591px;"> IGF-1</div> <div id="el69_ct" class="pw-tooltip" data-id="69"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/igf-i">IGF-I</a><br> </div> </div> <div id="el70_gry" class="msc_all msc_osteocytes pw-label el-gray70 pw-gray" style="top:419px;left:591px;"> Wnt-10b </div> <div id="el70_off" data-id="70" data-set="Wnt-10b" data-type="No Products Click" class="msc_all msc_osteocytes pw-label el-off70" style="top:419px;left:591px;"> Wnt-10b</div> <div id="el70_ct" class="pw-tooltip" data-id="70"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/wnt-10b">Wnt-10b</a><br> </div> </div> <div id="el71_gry" class="msc_all msc_osteocytes pw-label el-gray71 pw-gray" style="top:401px;left:591px;"> Vitamin D3 </div> <div id="el71_off" data-id="71" data-set="VitaminD3" data-type="No Products Click" class="msc_all msc_osteocytes pw-label el-off71" style="top:401px;left:591px;"> Vitamin D3</div> <div id="el71_ct" class="pw-tooltip" data-id="71"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/vitamin-d3">Vitamin D3</a><br> </div> </div> <div id="el72_gry" class="msc_all msc_osteocytes pw-sprite el-gray72 pw-gray" style="top:460px;left:619px;"> </div> <div id="el72_off" data-id="72" data-set="MatureOsteoblast57" data-type="No Products Click" class="msc_all msc_osteocytes pw-sprite el-off72" style="top:460px;left:619px;"> </div> <div id="el72_ct" class="pw-tooltip" data-id="72"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bap1">BAP1</a><br> <a target="_blank" href="/target/igfbp-3">IGFBP-3</a><br> <a target="_blank" href="/target/runx2-cbfa1">RUNX2/CBFA1</a><br> <a target="_blank" href="/target/osterix-sp7">Osterix/Sp7</a><br> <a target="_blank" href="/target/osteocalcin">Osteocalcin</a><br> <a target="_blank" href="/target/osteopontin-opn">Osteopontin/OPN</a><br> <a target="_blank" href="/target/collagen-i">Collagen I</a><br> <a target="_blank" href="/target/fibronectin">Fibronectin</a><br> <a target="_blank" href="/target/biglycan">Biglycan</a><br> <a target="_blank" href="/target/sparc">SPARC</a><br> <a target="_blank" href="/target/msx2">MSX2</a><br> </div> </div> <div id="el73_gry" class="msc_all msc_osteocytes pw-label pw-center el-gray73 pw-gray" style="top:466px;left:619px;"> Mature<br>Osteoblasts </div> <div id="el73_off" data-id="73" data-set="MatureOsteoblast57" data-type="No Products Click" class="msc_all msc_osteocytes pw-label pw-center el-off73" style="top:466px;left:619px;"> Mature<br>Osteoblasts</div> <div id="el73_ct" class="pw-tooltip" data-id="73"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bap1">BAP1</a><br> <a target="_blank" href="/target/igfbp-3">IGFBP-3</a><br> <a target="_blank" href="/target/runx2-cbfa1">RUNX2/CBFA1</a><br> <a target="_blank" href="/target/osterix-sp7">Osterix/Sp7</a><br> <a target="_blank" href="/target/osteocalcin">Osteocalcin</a><br> <a target="_blank" 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target="_blank" href="/target/egf">EGF</a><br> <a target="_blank" href="/target/fgf-basic">FGF basic</a><br> <a target="_blank" href="/target/fgf-4">FGF-4</a><br> <a target="_blank" href="/target/hb-egf">HB-EGF</a><br> <a target="_blank" href="/target/il-6">IL-6</a><br> <a target="_blank" href="/target/pdgf-bb">PDGF-BB</a><br> <a target="_blank" href="/target/pdgf-bb">PDGF-BB</a><br> </div> </div> </div> <div id="pw-img"> <img id="cont-img" src="https://resources.rndsystems.com/images/Pathways/pathway-images/msc_markers_all.png" alt="Mesenchymal Stem Cell Differentiation Pathways & Lineage-specific Markers" style="height:680px"> </div> </div> <div id="pathway-description"><h2>Overview of Mesenchymal Stem Cells & Lineage-specific Markers</h2><p><p>Mesenchymal stem cells (MSCs) are defined as multipotent, self-renewing progenitors that can be differentiated into adipocytes, chondrocytes, and osteocytes. Originally identified in mouse bone marrow, MSCs have now been discovered in a variety of species and isolated from numerous tissues including adipose, placental, dental pulp, and umbilical cord. Despite the classical trilineage differentiation that functionally identifies MSCs, these cells have also been shown to differentiate into non-traditional lineages to produce cardiomyocytes, endothelial cells, hepatocytes, and neural cells. To date, the biological properties of MSC identification, differentiation, and function have yet to be confirmed <em>in vivo</em>, raising caution for the extrapolation of <em>in vitro</em> generated data. The mechanisms controlling MSC self-renewal and differentiation are thought to be influenced by a diverse set of growth factors, receptors, intracellular signaling molecules, and transcription factors. The factors depicted below are known to influence MSC multipotency, proliferation, and lineage commitment. MSCs and their differentiated progeny can be identified by the expression of a unique combination of cell surface markers and transcription factors. Unique identifiers for each cell can be viewed by clicking on that cell-type within the lineage pathway.</p>  <p>To learn more, please visit our <a href="https://www.rndsystems.com/products/mesenchymal-stem-cells">Mesenchymal Stem Cells Research Area</a>.</p></p></div> <div id="print-copy-form" class="accordion-wrapper"> <h3 class="builder-header builder-bead-type ui-accordion-header ui-helper-reset ui-state-default ui-corner-all ui-accordion-icons" data-toggle="collapse" data-target="#collapsePathwayRequest" aria-expanded="false" id="pathwayRequestAccordionHeader"> <span class="ui-accordion-header-icon" id="accordionArrow"></span> Get Print Copy of this Pathway </h3> <div class="collapse" id="collapsePathwayRequest"> <div id="pathwayRequestWebformWrapper"> <form class="webform-client-form webform-client-form-27981" action="/pathways/mesenchymal-stem-cell-differentiation-pathways-lineage-specific-markers" method="post" id="webform-client-form-27981" accept-charset="UTF-8"><div><div 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