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class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/658282" target="_blank" rel="noopener noreferrer">Massimo Caruso</a></span><div class="m-icon-custom text-color-inherit pl-xs inline-block"><a href="https://orcid.org/0000-0002-4412-2080" rel="noopener noreferrer" target="_blank"><img src="/_ipx/_/img/articleorcid.webp" onerror="this.setAttribute('data-error', 1)" data-nuxt-img srcset="/_ipx/_/img/articleorcid.webp 1x, /_ipx/_/img/articleorcid.webp 2x" class="w-4"></a></div><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/statics/img/design/default-user.png"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/3835734" target="_blank" rel="noopener noreferrer">Alfio Distefano</a></span><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/statics/img/design/default-user.png"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/1307695" target="_blank" rel="noopener noreferrer">Rosalia Emma</a></span><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/img/user_image/153273/Michelino_Di_Rosa.jpg"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/153273" target="_blank" rel="noopener noreferrer">Michelino Di Rosa</a></span><div class="m-icon-custom text-color-inherit pl-xs inline-block"><a href="https://orcid.org/0000-0002-1837-9325" rel="noopener noreferrer" target="_blank"><img src="/_ipx/_/img/articleorcid.webp" onerror="this.setAttribute('data-error', 1)" data-nuxt-img srcset="/_ipx/_/img/articleorcid.webp 1x, /_ipx/_/img/articleorcid.webp 2x" class="w-4"></a></div><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/statics/img/design/default-user.png"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/3298422" target="_blank" rel="noopener noreferrer">Giuseppe Carota</a></span><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><span><a href="https://sciprofiles.com/profile/author/RDlna1hlZXdLK3FYdm95VXNPeUxOUWZSWHI3d0VLb1BoL0JqRENVZysxST0=" target="_blank" rel="noopener noreferrer">Sonja Rust</a></span><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/img/user_image/73955/Riccardo_Polosa.png"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/73955" target="_blank" rel="noopener noreferrer">Riccardo Polosa</a></span><div class="m-icon-custom text-color-inherit pl-xs inline-block"><a href="https://orcid.org/0000-0002-8450-5721" rel="noopener noreferrer" target="_blank"><img src="/_ipx/_/img/articleorcid.webp" onerror="this.setAttribute('data-error', 1)" data-nuxt-img srcset="/_ipx/_/img/articleorcid.webp 1x, /_ipx/_/img/articleorcid.webp 2x" class="w-4"></a></div><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/img/user_image/559912/Pietro_Zuccarello.png"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/559912" target="_blank" rel="noopener noreferrer">Pietro Zuccarello</a></span><div class="m-icon-custom text-color-inherit pl-xs inline-block"><a href="https://orcid.org/0000-0002-7425-0032" rel="noopener noreferrer" target="_blank"><img src="/_ipx/_/img/articleorcid.webp" onerror="this.setAttribute('data-error', 1)" data-nuxt-img srcset="/_ipx/_/img/articleorcid.webp 1x, /_ipx/_/img/articleorcid.webp 2x" class="w-4"></a></div><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/img/user_image/449553/Margherita_Ferrante.png"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/449553" target="_blank" rel="noopener noreferrer">Margherita Ferrante</a></span><div class="m-icon-custom text-color-inherit pl-xs inline-block"><a href="https://orcid.org/0000-0001-7596-2464" rel="noopener noreferrer" target="_blank"><img src="/_ipx/_/img/articleorcid.webp" onerror="this.setAttribute('data-error', 1)" data-nuxt-img srcset="/_ipx/_/img/articleorcid.webp 1x, /_ipx/_/img/articleorcid.webp 2x" class="w-4"></a></div><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><span><a href="https://sciprofiles.com/profile/author/b3d5Vmk1eUV2aTlUblFiUlpiUUN1WmhvUXVvVUI1MUdtcTAvZXVpU2dXUT0=" target="_blank" rel="noopener noreferrer">Giuseppina Raciti</a></span><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/img/user_image/115724/Giovanni_Li_Volti.png"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/115724" target="_blank" rel="noopener noreferrer">Giovanni Li Volti</a></span><sup> *</sup><div class="m-icon-custom text-color-inherit pl-xs inline-block"><a href="https://orcid.org/0000-0002-8678-2183" rel="noopener noreferrer" target="_blank"><img src="/_ipx/_/img/articleorcid.webp" onerror="this.setAttribute('data-error', 1)" data-nuxt-img srcset="/_ipx/_/img/articleorcid.webp 1x, /_ipx/_/img/articleorcid.webp 2x" class="w-4"></a></div></span></span></div><div class="invisible absolute"><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/img/user_image/658282/Massimo_Caruso.jpeg"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/658282" target="_blank" rel="noopener noreferrer">Massimo Caruso</a></span><div class="m-icon-custom text-color-inherit pl-xs inline-block"><a href="https://orcid.org/0000-0002-4412-2080" rel="noopener noreferrer" target="_blank"><img src="/_ipx/_/img/articleorcid.webp" onerror="this.setAttribute('data-error', 1)" data-nuxt-img srcset="/_ipx/_/img/articleorcid.webp 1x, /_ipx/_/img/articleorcid.webp 2x" class="w-4"></a></div><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/statics/img/design/default-user.png"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/3835734" target="_blank" rel="noopener noreferrer">Alfio Distefano</a></span><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/statics/img/design/default-user.png"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/1307695" target="_blank" rel="noopener noreferrer">Rosalia Emma</a></span><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/img/user_image/153273/Michelino_Di_Rosa.jpg"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/153273" target="_blank" rel="noopener noreferrer">Michelino Di Rosa</a></span><div class="m-icon-custom text-color-inherit pl-xs inline-block"><a href="https://orcid.org/0000-0002-1837-9325" rel="noopener noreferrer" target="_blank"><img src="/_ipx/_/img/articleorcid.webp" onerror="this.setAttribute('data-error', 1)" data-nuxt-img srcset="/_ipx/_/img/articleorcid.webp 1x, /_ipx/_/img/articleorcid.webp 2x" class="w-4"></a></div><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/statics/img/design/default-user.png"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/3298422" target="_blank" rel="noopener noreferrer">Giuseppe Carota</a></span><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><span><a href="https://sciprofiles.com/profile/author/RDlna1hlZXdLK3FYdm95VXNPeUxOUWZSWHI3d0VLb1BoL0JqRENVZysxST0=" target="_blank" rel="noopener noreferrer">Sonja Rust</a></span><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/img/user_image/73955/Riccardo_Polosa.png"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/73955" target="_blank" rel="noopener noreferrer">Riccardo Polosa</a></span><div class="m-icon-custom text-color-inherit pl-xs inline-block"><a href="https://orcid.org/0000-0002-8450-5721" rel="noopener noreferrer" target="_blank"><img src="/_ipx/_/img/articleorcid.webp" onerror="this.setAttribute('data-error', 1)" data-nuxt-img srcset="/_ipx/_/img/articleorcid.webp 1x, /_ipx/_/img/articleorcid.webp 2x" class="w-4"></a></div><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/img/user_image/559912/Pietro_Zuccarello.png"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/559912" target="_blank" rel="noopener noreferrer">Pietro Zuccarello</a></span><div class="m-icon-custom text-color-inherit pl-xs inline-block"><a href="https://orcid.org/0000-0002-7425-0032" rel="noopener noreferrer" target="_blank"><img src="/_ipx/_/img/articleorcid.webp" onerror="this.setAttribute('data-error', 1)" data-nuxt-img srcset="/_ipx/_/img/articleorcid.webp 1x, /_ipx/_/img/articleorcid.webp 2x" class="w-4"></a></div><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/img/user_image/449553/Margherita_Ferrante.png"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/449553" target="_blank" rel="noopener noreferrer">Margherita Ferrante</a></span><div class="m-icon-custom text-color-inherit pl-xs inline-block"><a href="https://orcid.org/0000-0001-7596-2464" rel="noopener noreferrer" target="_blank"><img src="/_ipx/_/img/articleorcid.webp" onerror="this.setAttribute('data-error', 1)" data-nuxt-img srcset="/_ipx/_/img/articleorcid.webp 1x, /_ipx/_/img/articleorcid.webp 2x" class="w-4"></a></div><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><span><a href="https://sciprofiles.com/profile/author/b3d5Vmk1eUV2aTlUblFiUlpiUUN1WmhvUXVvVUI1MUdtcTAvZXVpU2dXUT0=" target="_blank" rel="noopener noreferrer">Giuseppina Raciti</a></span><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/img/user_image/115724/Giovanni_Li_Volti.png"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/115724" target="_blank" rel="noopener noreferrer">Giovanni Li Volti</a></span><sup> *</sup><div class="m-icon-custom text-color-inherit pl-xs inline-block"><a href="https://orcid.org/0000-0002-8678-2183" rel="noopener noreferrer" target="_blank"><img src="/_ipx/_/img/articleorcid.webp" onerror="this.setAttribute('data-error', 1)" data-nuxt-img srcset="/_ipx/_/img/articleorcid.webp 1x, /_ipx/_/img/articleorcid.webp 2x" class="w-4"></a></div></span></span></div></div><div style="display:none;" class="mt-sm"><button class="m-button m-button--sm m-button--tertiary rounded !inline-flex after:hidden bg-white" type="button"><span class="inline-flex h-full w-full items-center gap-2 whitespace-nowrap justify-center">Show more <svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" aria-hidden="true" role="img" data-testid="keyboard_arrow_down" style="" width="16" height="16" viewBox="0 0 16 16"></svg></span></button></div></div><p class="m-text text-sm text-color-error pt-sm">This version is not peer-reviewed</p></div></div><div class="py-md border-b border-color-default"><div class="m-select common-field bg-white"><div class="common-field__wrapper" data-headlessui-state><div class="relative w-full cursor-default"><div class="flex items-center"><button id="headlessui-listbox-button-mui-43676" type="button" aria-haspopup="listbox" aria-expanded="false" data-headlessui-state data-testid="select-activator" class="common-field__dropdown-input [&>span]:overflow-hidden h-10"><span class="flex w-full items-center gap-1 [&>span]:truncate"><span>Version 1</span></span><div class="flex"><svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" aria-hidden="true" role="img" data-testid="keyboard_arrow_down" class="duration-400 transition-transform" style="" width="24" height="24" viewBox="0 0 16 16"></svg></div></button></div></div></div></div><div class="pt-sm"><div class="flex"><p class="m-text text-xs">Submitted:</p><p class="m-text text-xs pl-xs">03 October 2020</p></div><div class="flex pt-sm"><p class="m-text text-xs">Posted: </p><p class="m-text text-xs pl-xs">06 October 2020</p></div></div><div class="pt-sm"><div><p class="m-text text-xs">You are already at the latest version </p></div></div><div></div></div><div class="py-md border-b border-color-default flex items-center justify-between" data-v-d8c082ee><div class="flex-none flex items-center" data-v-d8c082ee><span class="m-text text-xs pr-xs font-semibold flex-none" data-v-d8c082ee>Alerts</span><span data-v-d8c082ee></span></div><div class="m-switch flex items-center gap-2" data-v-d8c082ee><button class="relative inline-flex h-[1.4rem] w-[2.75rem] shrink-0 cursor-pointer items-center rounded-full border-2 border-color-transparent transition-colors duration-150 ease-out ui-focus-visible:ring-2 ui-focus-visible:ring-brand-bold ui-focus-visible:ring-opacity-75 bg-content-default hover:bg-content-bold active:bg-content-bolder" aria-label="Switch on" id="headlessui-switch-mui-43677" role="switch" type="button" tabindex="0" aria-checked="false" data-headlessui-state><span aria-hidden="true" class="pointer-events-none inline-block h-[1rem] w-[1rem] transform rounded-full bg-white shadow-lg ring-0 transition duration-200 ease-in-out translate-x-0.5"></span></button></div></div><div data-v-d8c082ee data-v-03f1a75d></div><div><h6 class="m-heading text-inherit m-h6 font-semibold pt-lg">Abstract</h6><div class="">Prevalence studies of current smoking among hospitalized COVID-19 patients demonstrated an unexpectedly low prevalence of current smoking among patients with COVID-19. The aim of the present proposal was to evaluate the effect of smoke from cigarettes on ACE-2 in bronchial epithelial cells. Normal bronchial epithelial cells (H292) were exposed to smoke by an air-liquid-interface (ALI) system and ACE-2 membrane protein expression was evaluated after 24 hours from exposure. Our transcriptomics data analysis showed a significant selective reduction of membrane ACE-2 expression (about 25%) following smoking exposure. Interestingly, we observed a positive direct correlation between ACE-2 reduction and nicotine delivery. Furthermore, by stratifying GSE52237 as a function of ACE-2 gene expression levels, we highlighted 1012 genes related to ACE-2 in smokers and 855 in non-smokers. Furthermore, we showed that 161 genes involved in the endocytosis process were highlighted using the online pathway tool KEGG. Finally, 11 genes were in common between the ACE-2 pathway in smokers and the genes regulated during endocytosis, while 12 genes with non-smokers. Interestingly, six in non-smokers and four genes in smokers were closely involved during the viral internalization process. Our data may offer a pharmaceutical role of nicotine as potential treatment option in COVID-19.</div></div><div data-v-3ce94018><div class="pt-lg" data-v-3ce94018><span class="m-text text-body font-semibold" data-v-3ce94018>Keywords: </span><span class="m-text text-body pt-sm" data-v-3ce94018></span></div></div><div class="flex-1 pt-lg mr-lg lg:pt-0" data-v-6afb3413><div class="pt-md" data-v-6afb3413><div class="flex flex-wrap lg:flex-nowrap items-center" data-v-6afb3413><span class="m-text text-body font-semibold" data-v-6afb3413>Subject: </span><span class="m-text text-body" data-v-6afb3413>Biology and Life Sciences</span><span class="" data-v-6afb3413> - </span><span class="m-text text-body" data-v-6afb3413>Biochemistry and Molecular Biology</span></div></div><div class="content-container" id="articleRef" data-v-6afb3413></div><div class="pt-lg" data-v-6afb3413><span class="m-text text-body font-semibold" data-v-6afb3413>Copyright: </span><span class="m-text text-body" data-v-6afb3413>This open access article is published under a <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" data-v-6afb3413><span class="hover:underline cursor-pointer text-color-link-bold" data-v-6afb3413>Creative Commons CC BY 4.0 license</span></a>, which permit the free download, distribution, and reuse, provided that the author and preprint are cited in any reuse.</span></div></div><div class="pt-md"></div><div class="pt-md lg:pt-lg" data-v-cdceca3c><div class="m-accordion mx-auto flex w-full flex-col gap-3 rounded-2xl bg-white" data-v-cdceca3c><div class="m-accordion__item border-b border-color-default" data-v-cdceca3c><button id="accordion-button-expand-0" aria-controls="accordion-panel-0" class="relative mb-xs flex w-full cursor-pointer py-md text-sm outline-offset-2" aria-expanded="true"><span class="text-sm">Recommended Articles</span><div class="absolute right-0 top-1/2 -translate-y-1/2"><svg xmlns="http://www.w3.org/2000/svg" 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The aim of the present proposal was to evaluate the effect of smoke from cigarettes on ACE-2 in bronchial epithelial cells. Normal bronchial epithelial cells (H292) were exposed to smoke by an air-liquid-interface (ALI) system and ACE-2 membrane protein expression was evaluated after 24 hours from exposure. Our transcriptomics data analysis showed a significant selective reduction of membrane ACE-2 expression (about 25%) following smoking exposure. Interestingly, we observed a positive direct correlation between ACE-2 reduction and nicotine delivery. Furthermore, by stratifying GSE52237 as a function of ACE-2 gene expression levels, we highlighted 1012 genes related to ACE-2 in smokers and 855 in non-smokers. Furthermore, we showed that 161 genes involved in the endocytosis process were highlighted using the online pathway tool KEGG. Finally, 11 genes were in common between the ACE-2 pathway in smokers and the genes regulated during endocytosis, while 12 genes with non-smokers. Interestingly, six in non-smokers and four genes in smokers were closely involved during the viral internalization process. Our data may offer a pharmaceutical role of nicotine as potential treatment option in COVID-19.","Role of Cigarette Smoke on ACE-2 Protein Membrane Expression in Bronchial Epithelial Cells Using an Air-Liquid Interface Model","ACE-2; nicotine; smoke; cigarette; epithelial cells.",false,[],{"id":135,"name":136},23,"Biochemistry and Molecular Biology",{"id":52,"name":53},{"id":139,"name":140},15,"Article","2020-10-03 00:24:32","2020-10-06 09:43:40",[144,152,158,163,170,175,180,187,194,201,206],{"id":145,"name":146,"email":147,"is_corresponding":132,"orcid_link":148,"author_mark":149,"sp_link":150,"avatar":151},146788,"Massimo Caruso","mascaru@unict.it","https://orcid.org/0000-0002-4412-2080","","https://sciprofiles.com/profile/658282","/img/user_image/658282/Massimo_Caruso.jpeg",{"id":153,"name":154,"email":155,"is_corresponding":132,"orcid_link":47,"author_mark":149,"sp_link":156,"avatar":157},146789,"Alfio Distefano","distalfio@gmail.com","https://sciprofiles.com/profile/3835734","/statics/img/design/default-user.png",{"id":159,"name":160,"email":161,"is_corresponding":132,"orcid_link":47,"author_mark":149,"sp_link":162,"avatar":157},146790,"Rosalia Emma","rosalia.emma@studium.unict.it","https://sciprofiles.com/profile/1307695",{"id":164,"name":165,"email":166,"is_corresponding":132,"orcid_link":167,"author_mark":149,"sp_link":168,"avatar":169},146791,"Michelino Di Rosa","mdirosa@unict.it","https://orcid.org/0000-0002-1837-9325","https://sciprofiles.com/profile/153273","/img/user_image/153273/Michelino_Di_Rosa.jpg",{"id":171,"name":172,"email":173,"is_corresponding":132,"orcid_link":47,"author_mark":149,"sp_link":174,"avatar":157},146792,"Giuseppe Carota","giuseppe-carota@outlook.it","https://sciprofiles.com/profile/3298422",{"id":176,"name":177,"email":178,"is_corresponding":132,"orcid_link":47,"author_mark":149,"sp_link":179,"avatar":47},146793,"Sonja Rust","sonja.rust@eclatrbc.it","https://sciprofiles.com/profile/author/RDlna1hlZXdLK3FYdm95VXNPeUxOUWZSWHI3d0VLb1BoL0JqRENVZysxST0=",{"id":181,"name":182,"email":183,"is_corresponding":132,"orcid_link":184,"author_mark":149,"sp_link":185,"avatar":186},146794,"Riccardo Polosa","polosa@unict.it","https://orcid.org/0000-0002-8450-5721","https://sciprofiles.com/profile/73955","/img/user_image/73955/Riccardo_Polosa.png",{"id":188,"name":189,"email":190,"is_corresponding":132,"orcid_link":191,"author_mark":149,"sp_link":192,"avatar":193},146795,"Pietro Zuccarello","pietro.zuccarello@unict.it","https://orcid.org/0000-0002-7425-0032","https://sciprofiles.com/profile/559912","/img/user_image/559912/Pietro_Zuccarello.png",{"id":195,"name":196,"email":197,"is_corresponding":132,"orcid_link":198,"author_mark":149,"sp_link":199,"avatar":200},146796,"Margherita Ferrante","marfer@unict.it","https://orcid.org/0000-0001-7596-2464","https://sciprofiles.com/profile/449553","/img/user_image/449553/Margherita_Ferrante.png",{"id":202,"name":203,"email":204,"is_corresponding":132,"orcid_link":47,"author_mark":149,"sp_link":205,"avatar":47},146797,"Giuseppina Raciti","racitigi@unict.it","https://sciprofiles.com/profile/author/b3d5Vmk1eUV2aTlUblFiUlpiUUN1WmhvUXVvVUI1MUdtcTAvZXVpU2dXUT0=",{"id":207,"name":208,"email":209,"is_corresponding":6,"orcid_link":210,"author_mark":211,"sp_link":212,"avatar":213},146798,"Giovanni Li Volti","livolti@unict.it","https://orcid.org/0000-0002-8678-2183","*","https://sciprofiles.com/profile/115724","/img/user_image/115724/Giovanni_Li_Volti.png",{"filename":215,"url":216,"filesize":217},"final_file.pdf","/frontend/manuscript/f06e747043bad982bbec092cc6f3e04d/download_pub",1086545,[],{"viewed":220,"downloaded":221},"2076","812",{"score":223,"detail_url":224},10,"https://preprints.altmetric.com/details/doi/10.20944/preprints202010.0114.v1",[226],{"version":7,"hash_key":127,"id":126,"change":47},"Caruso, M.; Distefano, A.; Emma, R.; Di Rosa, M.; Carota, G.; Rust, S.; Polosa, R.; Zuccarello, P.; Ferrante, M.; Raciti, G.; Li Volti, G. Role of Cigarette Smoke on ACE-2 Protein Membrane Expression in Bronchial Epithelial Cells Using an Air-Liquid Interface Model. \u003Cem>Preprints\u003C/em> \u003Cb>2020\u003C/b>, 2020100114. 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