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You can connect with Mary on LinkedIn."/><meta property="og:url" content="https://www.ajmc.com/authors/mary-caffrey "/><meta property="og:title" content="Mary Caffrey"/><meta property="og:image" content="https://s3.amazonaws.com/mjhlifesciences.com/sitelogos/AJMC_1200x637.png"/><meta property="og:site_name" content="AJMC"/><meta property="og:description" content="Mary Caffrey is the Executive Editor for The American Journal of Managed Care® (AJMC®). She joined AJMC® in 2013 and is the primary staff editor for Evidence-Based Oncology, the multistakeholder publication that reaches 22,000+ oncology providers, policy makers and formulary decision makers. She is also part of the team that oversees speaker recruitment and panel preparations for AJMC®'s premier annual oncology meeting, Patient-Centered Oncology Care®. For more than a decade, Mary has covered ASCO, ASH, ACC and other leading scientific meetings for AJMC readers. Mary has a BA in communications and philosophy from Loyola University New Orleans. You can connect with Mary on LinkedIn."/><meta name="twitter:card" content="summary"/><meta name="twitter:title" content="Mary Caffrey"/><meta name="twitter:image" content="https://s3.amazonaws.com/mjhlifesciences.com/sitelogos/AJMC_1200x637.png"/><meta name="twitter:site" content="@@AJMC_Journal"/><meta name="twitter:description" content="Mary Caffrey is the Executive Editor for The American Journal of Managed Care® (AJMC®). She joined AJMC® in 2013 and is the primary staff editor for Evidence-Based Oncology, the multistakeholder publication that reaches 22,000+ oncology providers, policy makers and formulary decision makers. She is also part of the team that oversees speaker recruitment and panel preparations for AJMC®'s premier annual oncology meeting, Patient-Centered Oncology Care®. For more than a decade, Mary has covered ASCO, ASH, ACC and other leading scientific meetings for AJMC readers. Mary has a BA in communications and philosophy from Loyola University New Orleans. 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class="text-primary" href="/authors"> / <span class="">authors</span></a><span class="text-gray-400"> / <span class=" text-gray-400">mary-caffrey</span></span></div><div class="flex justify-end gap-2"></div><div class="mb-12 flex flex-col sm:flex-row"><div id="description-summary" class="py-2 text-sm text-gray-500 sm:w-[calc(100%-100px)]"><div class="blockText_blockContent__TbCXh"><p class="pb-2">Mary Caffrey is the Executive Editor for The American Journal of Managed Care® (<em>AJMC</em>®). She joined AJMC® in 2013 and is the primary staff editor for <em>Evidence-Based Oncology, </em>the multistakeholder publication that reaches 22,000+ oncology providers, policy makers and formulary decision makers. She is also part of the team that oversees speaker recruitment and panel preparations for <em>AJMC</em>®'s premier annual oncology meeting, Patient-Centered Oncology Care®. For more than a decade, Mary has covered ASCO, ASH, ACC and other leading scientific meetings for <em>AJMC</em> readers. </p><p class="pb-2">Mary has a BA in communications and philosophy from Loyola University New Orleans. You can connect with Mary on <a rel="nofollow noreferrer noopener" target="_blank" href="https://www.linkedin.com/in/marykcaffrey/">LinkedIn</a>.</p></div></div></div><h3 class="text-3xl mb-2">Articles</h3><div class="w-full mb-2 border border-secondary"></div><div class="flex flex-wrap w-full"><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/to-improve-clinical-trial-equity-in-multiple-myeloma-just-ask"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span 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style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">November 21st 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/putting-patients-first-by-extending-the-reach-of-world-class-care">Putting Patients First by Extending the Reach of World-Class Care</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/putting-patients-first-by-extending-the-reach-of-world-class-care"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Institute for Value-Based Medicine event with City of Hope.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="flex md:hidden justify-center items-center"></div><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/as-myeloma-trials-tackle-frontline-treatment-where-are-the-black-patients-"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span 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Winston Kirton" title="WINSTON KIRTON, JD | Image credit: Courtesy of Winston Kirton" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2fd6a38066630e07533c23a835be9b64028253a4-2400x1587.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2fd6a38066630e07533c23a835be9b64028253a4-2400x1587.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2fd6a38066630e07533c23a835be9b64028253a4-2400x1587.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2fd6a38066630e07533c23a835be9b64028253a4-2400x1587.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2fd6a38066630e07533c23a835be9b64028253a4-2400x1587.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, 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style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">November 20th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/as-myeloma-trials-tackle-frontline-treatment-where-are-the-black-patients-">As Myeloma Trials Tackle Frontline Treatment, Where Are the Black Patients?</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/ryan-flinn">Ryan Flinn</a><span class="mr-1 ml-[1px]"> </span><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/as-myeloma-trials-tackle-frontline-treatment-where-are-the-black-patients-"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><div class="text-sm text-gray-500 py-1 sm:pl-4"><div class="blockText_blockContent__TbCXh"></div></div><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/kraken-oral-muvalaplin-safely-lowers-lp-a-in-early-stage-trial"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:66.66259765625%"></span><img alt="Blood test | Image: Edward Jenner for Pexels" title="Blood test | Image: Edward Jenner for Pexels" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Blood test | Image: Edward Jenner for Pexels" title="Blood test | Image: Edward Jenner for Pexels" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fba7aefa89bdc1169ec3566ccea614e62d7ac7dff-8192x5461.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fba7aefa89bdc1169ec3566ccea614e62d7ac7dff-8192x5461.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fba7aefa89bdc1169ec3566ccea614e62d7ac7dff-8192x5461.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fba7aefa89bdc1169ec3566ccea614e62d7ac7dff-8192x5461.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fba7aefa89bdc1169ec3566ccea614e62d7ac7dff-8192x5461.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, 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style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">November 18th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/kraken-oral-muvalaplin-safely-lowers-lp-a-in-early-stage-trial">KRAKEN: Oral Muvalaplin Safely Lowers Lp(a) in Early-Stage Trial</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/kraken-oral-muvalaplin-safely-lowers-lp-a-in-early-stage-trial"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Results bring more competition to treat this genetically driven target for cardiovascular risk.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/cardiomyopathy-risk-plummets-when-sacubitril-valsartan-taken-with-chemo"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:66.41666666666667%"></span><img alt="Entresto packaging | Image credit: Novartis" title="Entresto packaging | Image credit: Novartis" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Entresto packaging | Image credit: Novartis" title="Entresto packaging | Image credit: Novartis" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F8132c39d1104aa281fcfc366c4a00b16f1e55b7a-3600x2391.webp%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F8132c39d1104aa281fcfc366c4a00b16f1e55b7a-3600x2391.webp%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F8132c39d1104aa281fcfc366c4a00b16f1e55b7a-3600x2391.webp%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F8132c39d1104aa281fcfc366c4a00b16f1e55b7a-3600x2391.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F8132c39d1104aa281fcfc366c4a00b16f1e55b7a-3600x2391.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, 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style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">November 18th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/cardiomyopathy-risk-plummets-when-sacubitril-valsartan-taken-with-chemo">Cardiomyopathy Risk Plummets When Sacubitril/Valsartan Taken With Chemo</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/cardiomyopathy-risk-plummets-when-sacubitril-valsartan-taken-with-chemo"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">The SARAH trial was limited to high-risk patients, which the lead investigator said prevented unnecessary exposure to adverse events in patients less at risk of cardiomyopathy.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/benefits-of-finerenone-similar-in-women-and-men-analysis-finds"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:65.94090202177294%"></span><img alt="Kerendia press photo | Image credit: Bayer" title="Kerendia press photo | Image credit: Bayer" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Kerendia press photo | Image credit: Bayer" title="Kerendia press photo | Image credit: Bayer" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4c28a41c67fa9ac394c18e7718d3c41f589c6c73-643x424.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4c28a41c67fa9ac394c18e7718d3c41f589c6c73-643x424.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4c28a41c67fa9ac394c18e7718d3c41f589c6c73-643x424.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4c28a41c67fa9ac394c18e7718d3c41f589c6c73-643x424.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4c28a41c67fa9ac394c18e7718d3c41f589c6c73-643x424.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4c28a41c67fa9ac394c18e7718d3c41f589c6c73-643x424.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4c28a41c67fa9ac394c18e7718d3c41f589c6c73-643x424.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4c28a41c67fa9ac394c18e7718d3c41f589c6c73-643x424.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4c28a41c67fa9ac394c18e7718d3c41f589c6c73-643x424.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">November 18th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/benefits-of-finerenone-similar-in-women-and-men-analysis-finds">Benefits of Finerenone Similar in Women and Men, Analysis Finds</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/benefits-of-finerenone-similar-in-women-and-men-analysis-finds"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Follow-up results for the FINEARTS-HF trial focused on specific results for women and men, hyperkalemia risk, and an analysis of the elements of its composite end point.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/education-feedback-boosts-pharmacists-hf-medication-rates"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:66.66666666666666%"></span><img alt="Alexander T. Sandhu, MD, MS | Image credit: Standford University" title="Alexander T. Sandhu, MD, MS | Image credit: Standford University" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Alexander T. Sandhu, MD, MS | Image credit: Standford University" title="Alexander T. Sandhu, MD, MS | Image credit: Standford University" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2e8b666554a76992d41e69b36a0fb1624bb092b4-678x452.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2e8b666554a76992d41e69b36a0fb1624bb092b4-678x452.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2e8b666554a76992d41e69b36a0fb1624bb092b4-678x452.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2e8b666554a76992d41e69b36a0fb1624bb092b4-678x452.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2e8b666554a76992d41e69b36a0fb1624bb092b4-678x452.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2e8b666554a76992d41e69b36a0fb1624bb092b4-678x452.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2e8b666554a76992d41e69b36a0fb1624bb092b4-678x452.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2e8b666554a76992d41e69b36a0fb1624bb092b4-678x452.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2e8b666554a76992d41e69b36a0fb1624bb092b4-678x452.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">November 17th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/education-feedback-boosts-pharmacists-hf-medication-rates">Education, Feedback Boosts Pharmacists’ HF Medication Rates</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/education-feedback-boosts-pharmacists-hf-medication-rates"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Lead study author Alexander T. Sandhu, MD, MS, of Stanford said the team will evaluate behavior to understand the results.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/from-benefit-status-to-transplants-cv-disparities-prove-tough-to-tackle"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:75%"></span><img alt="AHA Poster Hall | Image credit: Mary Caffrey for AJMC" title="AHA Poster Hall | Image credit: Mary Caffrey for AJMC" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="AHA Poster Hall | Image credit: Mary Caffrey for AJMC" title="AHA Poster Hall | Image credit: Mary Caffrey for AJMC" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F202782023761b2fd393f9f9a10afe179b1f1eab6-640x480.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F202782023761b2fd393f9f9a10afe179b1f1eab6-640x480.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F202782023761b2fd393f9f9a10afe179b1f1eab6-640x480.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F202782023761b2fd393f9f9a10afe179b1f1eab6-640x480.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F202782023761b2fd393f9f9a10afe179b1f1eab6-640x480.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, 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style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">November 16th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/from-benefit-status-to-transplants-cv-disparities-prove-tough-to-tackle">From Benefit Status to Transplants, CV Disparities Prove Tough to Tackle</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/from-benefit-status-to-transplants-cv-disparities-prove-tough-to-tackle"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Posters presented at the American Heart Association Scientific Sessions included results that show how persistent disparities are in cardiovascular (CV) health.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="flex md:hidden justify-center items-center"></div><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/for-obesity-and-hfpef-tirzepatide-cuts-risk-of-cv-death-or-worsening-hf-by-38-"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="Milton Packer, MD | Image credit: Baylor, Scott, and White" title="Milton Packer, MD | Image credit: Baylor, Scott, and White" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Milton Packer, MD | Image credit: Baylor, Scott, and White" title="Milton Packer, MD | Image credit: Baylor, Scott, and White" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2784fd6094a7c984b3c924ea60af0dad335d6227-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2784fd6094a7c984b3c924ea60af0dad335d6227-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2784fd6094a7c984b3c924ea60af0dad335d6227-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2784fd6094a7c984b3c924ea60af0dad335d6227-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2784fd6094a7c984b3c924ea60af0dad335d6227-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2784fd6094a7c984b3c924ea60af0dad335d6227-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2784fd6094a7c984b3c924ea60af0dad335d6227-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2784fd6094a7c984b3c924ea60af0dad335d6227-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2784fd6094a7c984b3c924ea60af0dad335d6227-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">November 16th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/for-obesity-and-hfpef-tirzepatide-cuts-risk-of-cv-death-or-worsening-hf-by-38-">For Obesity and HFpEF, Tirzepatide Cuts Risk of CV Death or Worsening HF by 38%</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/for-obesity-and-hfpef-tirzepatide-cuts-risk-of-cv-death-or-worsening-hf-by-38-"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Payers and employers have tightened access to the glucagon-like peptide 1 receptor agonist class once these therapies became more commonly prescribed for obesity.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/studies-highlight-prognostic-value-of-neutrophil-to-lymphocyte-ratio-in-mpns"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:97%"></span><img alt="Neutrophil | Image: Blausen Medical 2014" title="Neutrophil | Image: Blausen Medical 2014" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Neutrophil | Image: Blausen Medical 2014" title="Neutrophil | Image: Blausen Medical 2014" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0e68d9ede29b679c285d53904f03101d53a0d1d9-800x776.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0e68d9ede29b679c285d53904f03101d53a0d1d9-800x776.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0e68d9ede29b679c285d53904f03101d53a0d1d9-800x776.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0e68d9ede29b679c285d53904f03101d53a0d1d9-800x776.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0e68d9ede29b679c285d53904f03101d53a0d1d9-800x776.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0e68d9ede29b679c285d53904f03101d53a0d1d9-800x776.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0e68d9ede29b679c285d53904f03101d53a0d1d9-800x776.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0e68d9ede29b679c285d53904f03101d53a0d1d9-800x776.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0e68d9ede29b679c285d53904f03101d53a0d1d9-800x776.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">November 14th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/studies-highlight-prognostic-value-of-neutrophil-to-lymphocyte-ratio-in-mpns">Studies Highlight Prognostic Value of Neutrophil-to-Lymphocyte Ratio in MPNs</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/studies-highlight-prognostic-value-of-neutrophil-to-lymphocyte-ratio-in-mpns"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">The key driver in both sets of findings is the relationship between neutrophils and inflammation.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/american-heart-association-to-celebrate-100th-year-in-chicago-where-it-all-began"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="AHA 100 years logo | Image credit: Am Heart Assoc" title="AHA 100 years logo | Image credit: Am Heart Assoc" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="AHA 100 years logo | Image credit: Am Heart Assoc" title="AHA 100 years logo | Image credit: Am Heart Assoc" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F1639b0ef9f54fb67b2518eb8b99f941079ac89bd-225x225.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F1639b0ef9f54fb67b2518eb8b99f941079ac89bd-225x225.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F1639b0ef9f54fb67b2518eb8b99f941079ac89bd-225x225.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F1639b0ef9f54fb67b2518eb8b99f941079ac89bd-225x225.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F1639b0ef9f54fb67b2518eb8b99f941079ac89bd-225x225.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F1639b0ef9f54fb67b2518eb8b99f941079ac89bd-225x225.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F1639b0ef9f54fb67b2518eb8b99f941079ac89bd-225x225.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F1639b0ef9f54fb67b2518eb8b99f941079ac89bd-225x225.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F1639b0ef9f54fb67b2518eb8b99f941079ac89bd-225x225.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">November 14th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/american-heart-association-to-celebrate-100th-year-in-chicago-where-it-all-began">American Heart Association to Celebrate 100th Year in Chicago, Where It All Began</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/american-heart-association-to-celebrate-100th-year-in-chicago-where-it-all-began"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Therapies for obesity and inhibitors for lipoprotein(a) (Lp[a]) are among those to be featured at the American Heart Association (AHA) Scientific Sessions November 16-18, 2024, which will take place in Chicago, where the AHA was founded 100 years ago.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/lower-pharmacy-costs-give-ruxolitinib-edge-for-patients-with-mf-and-anemia"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:24.524714828897338%"></span><img alt="MPN Congress logo | Image Credit: 16th International Congress on Myeloproliferative Neoplasms" title="MPN Congress logo | Image Credit: 16th International Congress on Myeloproliferative Neoplasms" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="MPN Congress logo | Image Credit: 16th International Congress on Myeloproliferative Neoplasms" title="MPN Congress logo | Image Credit: 16th International Congress on Myeloproliferative Neoplasms" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F427aa14d776ec9a4a35d22412a746f8a56f84a5a-2104x516.webp%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F427aa14d776ec9a4a35d22412a746f8a56f84a5a-2104x516.webp%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F427aa14d776ec9a4a35d22412a746f8a56f84a5a-2104x516.webp%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F427aa14d776ec9a4a35d22412a746f8a56f84a5a-2104x516.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F427aa14d776ec9a4a35d22412a746f8a56f84a5a-2104x516.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F427aa14d776ec9a4a35d22412a746f8a56f84a5a-2104x516.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F427aa14d776ec9a4a35d22412a746f8a56f84a5a-2104x516.webp%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F427aa14d776ec9a4a35d22412a746f8a56f84a5a-2104x516.webp%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F427aa14d776ec9a4a35d22412a746f8a56f84a5a-2104x516.webp%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">November 9th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/lower-pharmacy-costs-give-ruxolitinib-edge-for-patients-with-mf-and-anemia">Lower Pharmacy Costs Give Ruxolitinib Edge for Patients With MF and Anemia</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/lower-pharmacy-costs-give-ruxolitinib-edge-for-patients-with-mf-and-anemia"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Authors found the pharmacy costs for momelotinib were $11,095 higher per month, too much to offset higher transfusion costs for ruxolitinib.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/the-importance-of-symptomatic-improvement-in-mpn"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:56.484375%"></span><img alt="Screenshot of an interview with Ruben Mesa, MD" title="Screenshot of an interview with Ruben Mesa, MD" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Screenshot of an interview with Ruben Mesa, MD" title="Screenshot of an interview with Ruben Mesa, MD" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">November 3rd 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/the-importance-of-symptomatic-improvement-in-mpn">The Importance of Symptomatic Improvement in MPN</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/laura-joszt">Laura Joszt, MA</a><span class="mr-1 ml-[1px]"> </span><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/the-importance-of-symptomatic-improvement-in-mpn"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Symptomatic improvement on therapy for myeloproliferative neoplasms (MPNs) is very much based on the individual. Data does show momelotinib not only improved spleen size and anemia but also improved symptomatic burden.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/age-race-insurance-status-can-predict-cv-mortality-for-those-with-mpns"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:85.7%"></span><img alt="3D illustration of heart | Image Credit: yodiyim - stock.adobe.com" title="3D illustration of heart | Image Credit: yodiyim - stock.adobe.com" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="3D illustration of heart | Image Credit: yodiyim - stock.adobe.com" title="3D illustration of heart | Image Credit: yodiyim - stock.adobe.com" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F58e2d5920d2c45295713c2f25bd7dddc06890f3c-2000x1714.webp%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F58e2d5920d2c45295713c2f25bd7dddc06890f3c-2000x1714.webp%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F58e2d5920d2c45295713c2f25bd7dddc06890f3c-2000x1714.webp%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F58e2d5920d2c45295713c2f25bd7dddc06890f3c-2000x1714.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F58e2d5920d2c45295713c2f25bd7dddc06890f3c-2000x1714.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F58e2d5920d2c45295713c2f25bd7dddc06890f3c-2000x1714.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F58e2d5920d2c45295713c2f25bd7dddc06890f3c-2000x1714.webp%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F58e2d5920d2c45295713c2f25bd7dddc06890f3c-2000x1714.webp%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F58e2d5920d2c45295713c2f25bd7dddc06890f3c-2000x1714.webp%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">November 2nd 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/age-race-insurance-status-can-predict-cv-mortality-for-those-with-mpns">Age, Race, Insurance Status Can Predict CV Mortality for Those With MPNs</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/age-race-insurance-status-can-predict-cv-mortality-for-those-with-mpns"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Being married and having insurance can offer emotional support and financial stability to lead to early diagnosis and effective treatment, the authors found.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/table-multiple-myeloma-trials-november-2024"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:50%"></span><img alt="AJMC EBO logo | Image credit : AJMC" title="AJMC EBO logo | Image credit : AJMC" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="AJMC EBO logo | Image credit : AJMC" title="AJMC EBO logo | Image credit : AJMC" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0723758cc83d02a7256e488e9500ee675daa995f-480x240.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0723758cc83d02a7256e488e9500ee675daa995f-480x240.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0723758cc83d02a7256e488e9500ee675daa995f-480x240.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0723758cc83d02a7256e488e9500ee675daa995f-480x240.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0723758cc83d02a7256e488e9500ee675daa995f-480x240.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0723758cc83d02a7256e488e9500ee675daa995f-480x240.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0723758cc83d02a7256e488e9500ee675daa995f-480x240.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0723758cc83d02a7256e488e9500ee675daa995f-480x240.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F0723758cc83d02a7256e488e9500ee675daa995f-480x240.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">November 1st 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/table-multiple-myeloma-trials-november-2024">Table Multiple Myeloma Trials November 2024</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/ryan-flinn">Ryan Flinn</a><span class="mr-1 ml-[1px]"> </span><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/table-multiple-myeloma-trials-november-2024"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><div class="text-sm text-gray-500 py-1 sm:pl-4"><div class="blockText_blockContent__TbCXh"></div></div><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/treatment-differences-for-younger-vs-older-patients-with-mpns"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:56.484375%"></span><img alt="Ruben Mesa, MD" title="Ruben Mesa, MD" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Ruben Mesa, MD" title="Ruben Mesa, MD" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">October 30th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/treatment-differences-for-younger-vs-older-patients-with-mpns">Treatment Differences for Younger vs Older Patients With MPNs</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/laura-joszt">Laura Joszt, MA</a><span class="mr-1 ml-[1px]"> </span><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/treatment-differences-for-younger-vs-older-patients-with-mpns"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Therapy selection for younger patients with myeloproliferative neoplasms (MPNs) may be different based on the desire for fertility preservation, but they are also at greater risk of their disease progressing, explained Ruben Mesa, MD, FACP, of Atrium Health.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="flex md:hidden justify-center items-center"></div><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/beyond-mckesson-and-florida-cancer-specialists-deals-are-reshaping-community-oncology"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:52.33333333333333%"></span><img alt="Orange City ribbon-cutting | Image credit: FCS press release" title="Orange City ribbon-cutting | Image credit: FCS press release" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Orange City ribbon-cutting | Image credit: FCS press release" title="Orange City ribbon-cutting | Image credit: FCS press release" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4cc5fe49422965d25cd9df088a7f56d3a2de40b1-1200x628.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4cc5fe49422965d25cd9df088a7f56d3a2de40b1-1200x628.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4cc5fe49422965d25cd9df088a7f56d3a2de40b1-1200x628.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4cc5fe49422965d25cd9df088a7f56d3a2de40b1-1200x628.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4cc5fe49422965d25cd9df088a7f56d3a2de40b1-1200x628.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4cc5fe49422965d25cd9df088a7f56d3a2de40b1-1200x628.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4cc5fe49422965d25cd9df088a7f56d3a2de40b1-1200x628.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4cc5fe49422965d25cd9df088a7f56d3a2de40b1-1200x628.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F4cc5fe49422965d25cd9df088a7f56d3a2de40b1-1200x628.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">October 25th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/beyond-mckesson-and-florida-cancer-specialists-deals-are-reshaping-community-oncology">Beyond McKesson and Florida Cancer Specialists, Deals Are Reshaping Community Oncology </a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/beyond-mckesson-and-florida-cancer-specialists-deals-are-reshaping-community-oncology"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><div class="text-sm text-gray-500 py-1 sm:pl-4"><div class="blockText_blockContent__TbCXh"></div></div><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/exploring-possibilities-in-disease-modification-in-mpns"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:75.3%"></span><img alt="Polycythemia Vera | Image credit: Elizabeth L. Courville, MD, for ASH Image Bank" title="Polycythemia Vera | Image credit: Elizabeth L. Courville, MD, for ASH Image Bank" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Polycythemia Vera | Image credit: Elizabeth L. Courville, MD, for ASH Image Bank" title="Polycythemia Vera | Image credit: Elizabeth L. Courville, MD, for ASH Image Bank" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F14a6b21ff6a0db6f3639a6df2576bbfec59b5125-1000x753.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F14a6b21ff6a0db6f3639a6df2576bbfec59b5125-1000x753.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F14a6b21ff6a0db6f3639a6df2576bbfec59b5125-1000x753.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F14a6b21ff6a0db6f3639a6df2576bbfec59b5125-1000x753.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F14a6b21ff6a0db6f3639a6df2576bbfec59b5125-1000x753.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F14a6b21ff6a0db6f3639a6df2576bbfec59b5125-1000x753.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F14a6b21ff6a0db6f3639a6df2576bbfec59b5125-1000x753.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F14a6b21ff6a0db6f3639a6df2576bbfec59b5125-1000x753.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F14a6b21ff6a0db6f3639a6df2576bbfec59b5125-1000x753.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">October 25th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/exploring-possibilities-in-disease-modification-in-mpns">Exploring Possibilities in Disease Modification in MPNs</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/exploring-possibilities-in-disease-modification-in-mpns"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Experts are asking whether the study and treatment of myeloproliferative neoplasms (MPNs) is ready for a new era with new end points, with data that show how survival benefits are biologically linked to changes in the spleen, reduction in fibrosis, or other responses.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/recognizing-symptoms-of-myeloproliferative-neoplasms-and-clinical-trial-challenges"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:56.484375%"></span><img alt="Screenshot of an interview with Ruben Mesa, MD" title="Screenshot of an interview with Ruben Mesa, MD" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Screenshot of an interview with Ruben Mesa, MD" title="Screenshot of an interview with Ruben Mesa, MD" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2c8fd678c047fa3e0fe024461cb45eb5b505df8b-1280x723.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">October 24th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/recognizing-symptoms-of-myeloproliferative-neoplasms-and-clinical-trial-challenges">Recognizing Symptoms of Myeloproliferative Neoplasms and Clinical Trial Challenges</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a><span class="mr-1 ml-[1px]"> </span><a class="text-sm text-[#00ADEF] underline italic" href="/authors/laura-joszt">Laura Joszt, MA</a></div><a href="/view/recognizing-symptoms-of-myeloproliferative-neoplasms-and-clinical-trial-challenges"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">There can be a delay in diagnosis of myeloproliferative neoplasms as the symptoms of the diseases can be variable and common, such as fatigue, migraines, and difficulty concentrating, explained Ruben Mesa, MD, of Atrium Health.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/5-hot-health-care-topics-in-the-presidential-election"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:66.66666666666666%"></span><img alt="Young woman protester | Edmond Dantes for Pexels" title="Young woman protester | Edmond Dantes for Pexels" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Young woman protester | Edmond Dantes for Pexels" title="Young woman protester | Edmond Dantes for Pexels" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fb42b8c370929cdf254f2b111f6a2897c5c5e61c4-2250x1500.webp%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fb42b8c370929cdf254f2b111f6a2897c5c5e61c4-2250x1500.webp%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fb42b8c370929cdf254f2b111f6a2897c5c5e61c4-2250x1500.webp%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fb42b8c370929cdf254f2b111f6a2897c5c5e61c4-2250x1500.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fb42b8c370929cdf254f2b111f6a2897c5c5e61c4-2250x1500.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fb42b8c370929cdf254f2b111f6a2897c5c5e61c4-2250x1500.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fb42b8c370929cdf254f2b111f6a2897c5c5e61c4-2250x1500.webp%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fb42b8c370929cdf254f2b111f6a2897c5c5e61c4-2250x1500.webp%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fb42b8c370929cdf254f2b111f6a2897c5c5e61c4-2250x1500.webp%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">October 18th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/5-hot-health-care-topics-in-the-presidential-election">5 Hot Health Care Topics in the Presidential Election</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/5-hot-health-care-topics-in-the-presidential-election"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">A review of positions and track records of Vice President Kamala Harris and former President Donald Trump on reproductive health, the future of the Affordable Care Act, prescription drug costs, health care consolidation, and a proposed Medicare home health benefit. </p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/update-ruxolitinib-beats-best-available-therapy-in-treating-polycythemia-vera"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:40.625%"></span><img alt="Jakafi | Image: Novartis" title="Jakafi | Image: Novartis" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" 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src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F319d0e45ca554b625bc11c5362dfae95b694d3f3-352x143.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">October 14th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/update-ruxolitinib-beats-best-available-therapy-in-treating-polycythemia-vera">Update: Ruxolitinib Beats Best Available Therapy in Treating Polycythemia Vera</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/update-ruxolitinib-beats-best-available-therapy-in-treating-polycythemia-vera"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Investigators added more data to an analysis first published in 2020 and got the same result: ruxolitinib beats other treatments for polycythemia vera.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " 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style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Doing Things Differently: Wilfong Moves to Thyme Care" title="Doing Things Differently: Wilfong Moves to Thyme Care" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fed29aaf71328b1fba1857ed86e0593d810208a45-1280x717.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fed29aaf71328b1fba1857ed86e0593d810208a45-1280x717.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fed29aaf71328b1fba1857ed86e0593d810208a45-1280x717.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 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src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fed29aaf71328b1fba1857ed86e0593d810208a45-1280x717.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">October 12th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/doing-things-differently-wilfong-moves-to-thyme-care">Doing Things Differently: Wilfong Moves to Thyme Care</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/doing-things-differently-wilfong-moves-to-thyme-care"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Lalan Wilfong, MD, a 20-year medical oncologist with Texas Oncology, is senior vice president, value-based care, Thyme Care.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/beyond-navigation-thyme-care-ready-for-heavy-lifts-to-make-value-based-care-work"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:42.333333333333336%"></span><img alt="Thyme Care logo | Image : Thyme Care" title="Thyme Care logo | Image : Thyme Care" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Thyme Care logo | Image : Thyme Care" title="Thyme Care logo | Image : Thyme Care" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F7d26b0804cbbafc8d0ebccd51bd0b75b29932085-600x254.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F7d26b0804cbbafc8d0ebccd51bd0b75b29932085-600x254.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F7d26b0804cbbafc8d0ebccd51bd0b75b29932085-600x254.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, 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src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F7d26b0804cbbafc8d0ebccd51bd0b75b29932085-600x254.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">October 12th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/beyond-navigation-thyme-care-ready-for-heavy-lifts-to-make-value-based-care-work">Beyond Navigation: Thyme Care Ready for Heavy Lifts to Make Value-Based Care Work</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/beyond-navigation-thyme-care-ready-for-heavy-lifts-to-make-value-based-care-work"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><div class="text-sm text-gray-500 py-1 sm:pl-4"><div class="blockText_blockContent__TbCXh"></div></div><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/fda-approves-marstacimab-first-weekly-sub-q-option-for-hemophilia-b"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:75%"></span><img alt="Red blood cells | Image credit: Getty Images" title="Red blood cells | Image credit: Getty Images" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Red blood cells | Image credit: Getty Images" title="Red blood cells | Image credit: Getty Images" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fbdd66e8a02127e7e832a21fb412a6d54e1e3c079-600x450.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fbdd66e8a02127e7e832a21fb412a6d54e1e3c079-600x450.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fbdd66e8a02127e7e832a21fb412a6d54e1e3c079-600x450.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fbdd66e8a02127e7e832a21fb412a6d54e1e3c079-600x450.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fbdd66e8a02127e7e832a21fb412a6d54e1e3c079-600x450.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fbdd66e8a02127e7e832a21fb412a6d54e1e3c079-600x450.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fbdd66e8a02127e7e832a21fb412a6d54e1e3c079-600x450.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fbdd66e8a02127e7e832a21fb412a6d54e1e3c079-600x450.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fbdd66e8a02127e7e832a21fb412a6d54e1e3c079-600x450.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">October 11th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/fda-approves-marstacimab-first-weekly-sub-q-option-for-hemophilia-b">FDA Approves Marstacimab, First Weekly Sub-Q Option for Hemophilia B</a></p><div class=" sm:pl-4"><a 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href="/view/coming-soon-an-off-the-shelf-car-t-therapy-for-myeloma"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:87%"></span><img alt="CAR T-cell therapy | Image credit: Getty Images" title="CAR T-cell therapy | Image credit: Getty Images" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="CAR T-cell therapy | Image credit: Getty Images" title="CAR T-cell therapy | Image credit: Getty Images" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F6de7f7c13942b90bfa6f3f8c592f39972b319b79-600x522.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F6de7f7c13942b90bfa6f3f8c592f39972b319b79-600x522.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F6de7f7c13942b90bfa6f3f8c592f39972b319b79-600x522.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F6de7f7c13942b90bfa6f3f8c592f39972b319b79-600x522.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F6de7f7c13942b90bfa6f3f8c592f39972b319b79-600x522.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F6de7f7c13942b90bfa6f3f8c592f39972b319b79-600x522.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F6de7f7c13942b90bfa6f3f8c592f39972b319b79-600x522.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F6de7f7c13942b90bfa6f3f8c592f39972b319b79-600x522.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F6de7f7c13942b90bfa6f3f8c592f39972b319b79-600x522.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">October 2nd 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/coming-soon-an-off-the-shelf-car-t-therapy-for-myeloma">Coming Soon: An Off-the-Shelf CAR T Therapy for Myeloma</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/coming-soon-an-off-the-shelf-car-t-therapy-for-myeloma"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Attendees at the International Myeloma Society 21st Annual Meeting & Exposition got an early look at data for an investigational allogeneic chimeric antigen receptor (CAR) T-cell product from healthy donor cells to prevent graft-versus-host disease.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/from-cars-to-trispecifics-more-choices-to-come-in-multiple-myeloma"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:66.66666666666666%"></span><img alt="Ajai Chari, MD | Image credit: UCSF" title="Ajai Chari, MD | Image credit: UCSF" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Ajai Chari, MD | Image credit: UCSF" title="Ajai Chari, MD | Image credit: UCSF" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F53aab9e36527b9d69f76fd0ba798272e254354f8-150x100.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F53aab9e36527b9d69f76fd0ba798272e254354f8-150x100.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F53aab9e36527b9d69f76fd0ba798272e254354f8-150x100.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, 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src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F53aab9e36527b9d69f76fd0ba798272e254354f8-150x100.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">October 1st 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/from-cars-to-trispecifics-more-choices-to-come-in-multiple-myeloma">From CARs to Trispecifics, More Choices to Come in Multiple Myeloma</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/from-cars-to-trispecifics-more-choices-to-come-in-multiple-myeloma"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Ajai Chari, MD, covered both recent FDA approvals and pipeline products, such as non-BCMA chimeric antigen receptor (CAR) T-cell therapies and trispecifics, during a symposium on Immunotherapy at the International Myeloma Society 21st Annual Meeting & Exposition.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/how-do-community-oncologists-view-the-use-of-mrd-testing-"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:56.15234375%"></span><img alt="Lucio N. Gordan, MD | Image credit: Florida Cancer Specialists & Research Institute" title="Lucio N. Gordan, MD | Image credit: Florida Cancer Specialists & Research Institute" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Lucio N. Gordan, MD | Image credit: Florida Cancer Specialists & Research Institute" title="Lucio N. Gordan, MD | Image credit: Florida Cancer Specialists & Research Institute" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fa66d02ada3e438ae27d6b576c56bf99253eb1840-1024x575.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fa66d02ada3e438ae27d6b576c56bf99253eb1840-1024x575.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fa66d02ada3e438ae27d6b576c56bf99253eb1840-1024x575.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fa66d02ada3e438ae27d6b576c56bf99253eb1840-1024x575.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fa66d02ada3e438ae27d6b576c56bf99253eb1840-1024x575.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fa66d02ada3e438ae27d6b576c56bf99253eb1840-1024x575.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fa66d02ada3e438ae27d6b576c56bf99253eb1840-1024x575.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fa66d02ada3e438ae27d6b576c56bf99253eb1840-1024x575.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fa66d02ada3e438ae27d6b576c56bf99253eb1840-1024x575.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">October 1st 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/how-do-community-oncologists-view-the-use-of-mrd-testing-">How Do Community Oncologists View the Use of MRD Testing?</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/how-do-community-oncologists-view-the-use-of-mrd-testing-"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Investigators from Florida Cancer Specialists & Research Institute explored questions surrounding minimal residual disease (MRD) negativity testing in an abstract presented at the International Myeloma Society 21st Annual Meeting & Exposition.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/cepheus-sub-q-daratumumab-with-vrd-improves-mrd-negativity-pfs-in-myeloma-if-transplant-deferred"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:52.25806451612903%"></span><img alt="Darzalex Faspro | Image: Johnson & Johnson" title="Darzalex Faspro | Image: Johnson & Johnson" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Darzalex Faspro | Image: Johnson & Johnson" title="Darzalex Faspro | Image: Johnson & Johnson" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F37c968c9893c8462a6bd0bde795a52c56023918d-310x162.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F37c968c9893c8462a6bd0bde795a52c56023918d-310x162.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F37c968c9893c8462a6bd0bde795a52c56023918d-310x162.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F37c968c9893c8462a6bd0bde795a52c56023918d-310x162.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F37c968c9893c8462a6bd0bde795a52c56023918d-310x162.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F37c968c9893c8462a6bd0bde795a52c56023918d-310x162.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F37c968c9893c8462a6bd0bde795a52c56023918d-310x162.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F37c968c9893c8462a6bd0bde795a52c56023918d-310x162.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F37c968c9893c8462a6bd0bde795a52c56023918d-310x162.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">September 27th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/cepheus-sub-q-daratumumab-with-vrd-improves-mrd-negativity-pfs-in-myeloma-if-transplant-deferred">CEPHEUS: Sub-Q Daratumumab With VRd Improves MRD Negativity, PFS in Myeloma if Transplant Deferred</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/cepheus-sub-q-daratumumab-with-vrd-improves-mrd-negativity-pfs-in-myeloma-if-transplant-deferred"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">The trial is seen as a complement to the MAIA trial, which had shown a significant overall survival benefit with daratumumab for patients with newly diagnosed multiple myeloma. </p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/talquetamab-combo-updates-show-durable-responses-in-heavily-pretreated-patients"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:66.54545454545455%"></span><img alt="Talvey (talquetamab) | Image: Johnson & Johnson" title="Talvey (talquetamab) | Image: Johnson & Johnson" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Talvey (talquetamab) | Image: Johnson & Johnson" title="Talvey (talquetamab) | Image: Johnson & Johnson" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F7d8e0b6621447764128aa0693cdc4e8b6d56b89e-275x183.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F7d8e0b6621447764128aa0693cdc4e8b6d56b89e-275x183.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F7d8e0b6621447764128aa0693cdc4e8b6d56b89e-275x183.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F7d8e0b6621447764128aa0693cdc4e8b6d56b89e-275x183.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F7d8e0b6621447764128aa0693cdc4e8b6d56b89e-275x183.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F7d8e0b6621447764128aa0693cdc4e8b6d56b89e-275x183.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F7d8e0b6621447764128aa0693cdc4e8b6d56b89e-275x183.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F7d8e0b6621447764128aa0693cdc4e8b6d56b89e-275x183.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F7d8e0b6621447764128aa0693cdc4e8b6d56b89e-275x183.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">September 27th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/talquetamab-combo-updates-show-durable-responses-in-heavily-pretreated-patients">Talquetamab Combo Updates Show Durable Responses in Heavily Pretreated Patients</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/talquetamab-combo-updates-show-durable-responses-in-heavily-pretreated-patients"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">An oral session Friday at the International Myeloma Society 21st Annual Meeting & Exposition offered updates for the TRIMM-2 and RedirecTT-1 trials.</p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div><div class="w-full h-full"><hr class="mt-1 w-full " style="border-top-width:2px;border-top-color:#F3F4F6"/><div class="w-full h-full"><div class="flex flex-col sm:flex-row justify-center align-center w-100% "><div class="flex flex-col justify-center sm:flex-row py-4 " style="background-color:transparent;border-color:#F3F4F6;border-width:0;border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem"><a href="/view/fine-tuning-ai-tools-to-make-meaningful-predictions-in-cancer"><div class="sm:w-[288px] h-100% mt-2"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:66.66666666666666%"></span><img alt="Anant Madabhushi, PhD | Image credit: Emory University" title="Anant Madabhushi, PhD | Image credit: Emory University" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Anant Madabhushi, PhD | Image credit: Emory University" title="Anant Madabhushi, PhD | Image credit: Emory University" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F75cff775d0f498c846477eac7ec897ab77346743-600x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F75cff775d0f498c846477eac7ec897ab77346743-600x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F75cff775d0f498c846477eac7ec897ab77346743-600x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F75cff775d0f498c846477eac7ec897ab77346743-600x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F75cff775d0f498c846477eac7ec897ab77346743-600x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F75cff775d0f498c846477eac7ec897ab77346743-600x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F75cff775d0f498c846477eac7ec897ab77346743-600x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F75cff775d0f498c846477eac7ec897ab77346743-600x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F75cff775d0f498c846477eac7ec897ab77346743-600x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="border-top-left-radius:0rem;border-top-right-radius:0rem;border-bottom-left-radius:0rem;border-bottom-right-radius:0rem;position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></div></a><div class="flex-auto w-auto sm:ml-8 flex-1"><span class="text-sm text-gray-500 italic sm:pl-4">September 27th 2024</span><p class="font-bold text-[1rem] sm:pl-4 text-undefined" style="font-size:1.125rem"><a href="/view/fine-tuning-ai-tools-to-make-meaningful-predictions-in-cancer">Fine-Tuning AI Tools to Make Meaningful Predictions in Cancer</a></p><div class=" sm:pl-4"><a class="text-sm text-[#00ADEF] underline italic" href="/authors/mary-caffrey">Mary Caffrey</a></div><a href="/view/fine-tuning-ai-tools-to-make-meaningful-predictions-in-cancer"><div class="mt-2 ml-4"></div><div class="flex flex-row gap-2"></div><p class=" text-sm text-gray-500 py-1 sm:pl-4">Anant Madabhushi, PhD, of Emory University, told attendees at the International Myeloma Society 21st Annual Meeting & Exposition how artificial intelligence's (AI) full potential in cancer care depends on its algorithms being validated by completed clinical trials. </p><div class="pl-4"></div></a><div class="flex flex-col sm:flex-row pl-2 mt-4"></div></div></div></div></div></div></div><div class="w-full text-center flex justify-center pb-24"><a class="px-4 py-2 border-y border-r bg-primary text-white" href="/authors/mary-caffrey?page=1">1</a><a class="px-4 py-2 border-y border-r " href="/authors/mary-caffrey?page=2">2</a><a class="px-4 py-2 border-y border-r " href="/authors/mary-caffrey?page=3">3</a><a 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The phase 1/2 AUGMENT-101 study demonstrated a 21.2% complete remission rate with a median duration of 6.4 months. Additionally, 14% of patients achieved independence from red blood cell and platelet transfusions. Common adverse effects included hemorrhage, nausea, increased phosphate levels, and musculoskeletal pain. The approval marks a significant advancement in targeted therapy for this specific leukemia subset.","body":[{"_type":"block","style":"normal","_key":"75a54d3e9100","markDefs":[{"_key":"6fc46bcc034d","nofollow":false,"blank":true,"_type":"link","href":"https://www.onclive.com/view/fda-approves-revumenib-for-r-r-acute-leukemia-with-a-kmt2a-translocation"}],"children":[{"text":"This article originally ","_key":"e7a4b0e240c5","_type":"span","marks":["em"]},{"text":"appeared on ","_key":"e1d44958d5bf","_type":"span","marks":["6fc46bcc034d","em"]},{"_type":"span","marks":["6fc46bcc034d"],"text":"OncLive","_key":"c10873644e3d"},{"_type":"span","marks":["6fc46bcc034d","em","superscript"],"text":"®","_key":"7c1005484389"},{"_type":"span","marks":["em"],"text":". ","_key":"ab19c0597360"}]},{"alignment":"right","alt":"FDA approval with stamp. | Image Credit: Surendra - stock.adobe.com","asset":{"_type":"reference","_ref":"image-ca845f7e6dfc35ab2f006b74744bb6c3a34fff11-5500x4093-jpg"},"disableLightBox":true,"imgcaption":[{"_key":"a067baf383a9","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The AUGMENT-101 study showed a 21.2% complete remission rate with a median duration of 6.4 months.","_key":"fc66d38024f00"}],"_type":"block","style":"normal"},{"children":[{"_type":"span","marks":[],"text":"Image Credit: Surendra - stock.adobe.com","_key":"7383d15cd9ce0"}],"_type":"block","style":"normal","_key":"fca696b1ae87","markDefs":[]}],"disableTextWrap":false,"_key":"7ee0b2c1ded7","widthP":30,"_type":"figure"},{"style":"normal","_key":"b1b9e2f40530","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The FDA has approved revumenib (Revuforj) for the treatment of adult and pediatric patients aged 1 year and older with relapsed or refractory acute leukemia and a ","_key":"64a870eb73c20"},{"_type":"span","marks":["em"],"text":"KMT2A","_key":"64a870eb73c21"},{"_key":"64a870eb73c22","_type":"span","marks":[],"text":" translocation."},{"_type":"span","marks":["superscript"],"text":"1,2","_key":"481cf1ebac26"}],"_type":"block"},{"children":[{"_key":"5fbd664ed9790","_type":"span","marks":[],"text":"Data from the phase 1/2 AUGMENT-101 study (SNDX-5613-0700; NCT04065399) showed that the menin inhibitor (n = 104) led to a complete remission (CR) plus CR with partial hematologic recovery (CRh; CR+CRh) rate of 21.2% (95% CI, 13.8%-30.3%) with a median duration of CR+CRh of 6.4 months (95% CI, 2.7-not estimable [NE]). In the patients who achieved a CR or CRh with revumenib (n = 22), the median time to response was 1.9 months (range, 0.9-5.6)."}],"_type":"block","style":"normal","_key":"88fafc22b989","markDefs":[]},{"_key":"ea2a79ce7b2f","markDefs":[],"children":[{"marks":[],"text":"Moreover, 14% of 83 patients who were dependent on red blood cell (RBC) and platelet transfusions at baseline achieved independence during any 56-day post-baseline period, and 48% of 21 patients who were independent at baseline remained independent.","_key":"58283f709cee0","_type":"span"}],"_type":"block","style":"normal"},{"style":"normal","_key":"01303d417a94","markDefs":[],"children":[{"_type":"span","marks":[],"text":"\"The FDA approval of the first menin inhibitor is a major breakthrough for patients with R/R acute leukemia with a KMT2A translocation, a genetic alteration associated with a very poor prognosis,\" Ghayas C. Issa, MD, associate professor of leukemia at The University of Texas MD Anderson Cancer Center, stated in a news release.","_key":"7f590bcc55210"},{"_type":"span","marks":["superscript"],"text":"3","_key":"03a636a59bd9"},{"marks":[],"text":" \"The significant clinical benefit and robust efficacy seen with Revuforj represents a substantial improvement over what has been historically observed in these patients with previously available therapies and has the potential to be an important new treatment option for patients.\"","_key":"3e163ccac259","_type":"span"}],"_type":"block"},{"markDefs":[],"children":[{"marks":[],"text":"About AUGMENT-101: Eligibility, Treatment, Objectives","_key":"c5baa97694080","_type":"span"}],"_type":"block","style":"h2","_key":"caf56161dc85"},{"_type":"block","style":"normal","_key":"4be4a82a9b71","markDefs":[],"children":[{"_key":"60efbe4b7b400","_type":"span","marks":[],"text":"The single-arm cohort of an open-label, multicenter trial enrolled adult and pediatric patients at least 30 days old who had relapsed or refractory acute leukemia harboring a "},{"text":"KMT2A","_key":"60efbe4b7b401","_type":"span","marks":["em"]},{"marks":[],"text":" translocation.","_key":"60efbe4b7b402","_type":"span"},{"_type":"span","marks":["superscript"],"text":"2","_key":"3fc3c488e08a"},{"_type":"span","marks":[],"text":" To be eligible, patients needed to have a corrected QT interval of less than 450 milliseconds. Those with an 11q23 partial tandem duplication were not permitted.","_key":"1ce489011e54"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Revumenib was administered at a dose that was approximately equivalent to 160 mg in adults orally twice daily with a strong CYP3A4 inhibitor. Treatment continued until progressive disease, intolerable toxicity, failure to achieve a morphological leukemia-free state by 4 cycles of treatment, or hematopoietic stem cell transplantation.","_key":"d01dd4e423a70"}],"_type":"block","style":"normal","_key":"d0ab137320ee"},{"markDefs":[],"children":[{"_key":"86a8313307100","_type":"span","marks":[],"text":"The primary end point was CR+CRh rate."}],"_type":"block","style":"normal","_key":"1e5889fb6f65"},{"_type":"block","style":"h2","_key":"eccf2043bd64","markDefs":[],"children":[{"text":"Diving Into Demographic and Disease Characteristics","_key":"94a09963addd0","_type":"span","marks":[]}]},{"style":"normal","_key":"4c9d30a6a9d4","markDefs":[],"children":[{"text":"In the cohort (n = 114) median patient age was 37 years (range, 1-79), with 24% younger than 17 years. More than half of the patients (64%) were female and most were White (72%) and not Hispanic or Latino (73%). Eighty-three percent of patients had AML, 15% had acute lymphoblastic leukemia, and 2% had mixed phenotype acute leukemia.","_key":"31ccd06ff1bd0","_type":"span","marks":[]}],"_type":"block"},{"_type":"block","style":"normal","_key":"2b316cbc320e","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Moreover, 22%, 19%, 10%, 10%, 7%, 3%, 2%, 2%, and 1% of patients had t(9;11), t(11;19), t(6;11), t(10;11), t(4;11), t(1;11), t(11;17), t(11;22), and t(11;16), respectively. Twenty-five percent of patients had an unknown ","_key":"403fe5978d4d0"},{"_key":"403fe5978d4d1","_type":"span","marks":["em"],"text":"KMT2A"},{"_key":"403fe5978d4d2","_type":"span","marks":[],"text":" fusion partner. More than half of patients had relapsed/refractory disease (59%); 21% and 20% of patients had primary refractory or untreated relapsed disease."}]},{"_type":"block","style":"normal","_key":"54938d2c14af","markDefs":[],"children":[{"_key":"185d6e803ef30","_type":"span","marks":[],"text":"The median number of previous regimens received was 2, with a range of 1 to 11 regimens. Forty-four percent of patients underwent prior stem cell transplantation. Fifty-three percent of patients had 1 prior relapse, 19% had 2 prior relapses, and 7% had 3 or more prior relapses."}]},{"children":[{"_type":"span","marks":[],"text":"Additional Efficacy Data","_key":"68f131c663710"}],"_type":"block","style":"h2","_key":"74ce72833a61","markDefs":[]},{"markDefs":[],"children":[{"marks":[],"text":"The median follow-up was 5.73 months (range, 0.3-28.9). Additional findings showed that 12.5% (95% CI, 6.8%-20.4%) of patients achieved a CR and the median duration of CR was 4.3 months (95% CI, 1.0-NE). The CRh rate was 8.7% (95% CI, 4.0%-15.8%) and the median duration of CRh was 6.4 months (95% CI, 1.9-NE).","_key":"cdb806484d0c0","_type":"span"}],"_type":"block","style":"normal","_key":"dc1a1e0ed8f0"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Subgroup analysis revealed that CR+CRh was achieved in 21%, 19%, and 50% of patients with AML (n = 18/86), ALL (n = 3/16), and MPAL (n = 1/2), respectively.","_key":"6e0c2b23b6950"}],"_type":"block","style":"normal","_key":"c6611d7571c6"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Shedding Light on Safety","_key":"1d36479124190"}],"_type":"block","style":"h2","_key":"4d84d2fec6e5"},{"_type":"block","style":"normal","_key":"cf2f62aae15b","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The safety of revumenib was examined in 104 adult patients and 31 pediatric patients with relapsed or refractory acute leukemia and a ","_key":"ff02a9a9125c0"},{"text":"KMT2A","_key":"ff02a9a9125c1","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":" translocation. The median duration of exposure was 2.3 months (range, \u003c1-23).","_key":"ff02a9a9125c2"}]},{"children":[{"_type":"span","marks":[],"text":"The most common toxicities experienced by at least 20% of patients included hemorrhage (all grade, 53%; grade 3/4, 9%), nausea (51%; 4%), musculoskeletal pain (42%; 6%), infection (41%; 29%), febrile neutropenia (35%; 33%), bacterial infection (31%; 20%), diarrhea (30%; 4%), differentiation syndrome (29%; 13%), prolonged electrocardiogram QT (29%; 12%), decreased appetite (24%; 8%), constipation (23%; 1%) viral infection (23%; 4%), edema (23%; 1%), fatigue (22%; 5%), thrombosis (10%; 5%), and leukocytosis (8%; 5%).","_key":"d9ec4c2503750"}],"_type":"block","style":"normal","_key":"fe84a54a4fb3","markDefs":[]},{"_key":"aebd2809d7c6","markDefs":[],"children":[{"marks":[],"text":"Forty-two percent of patients experienced adverse effects (AEs) that required dose interruptions and 10% experienced AEs that led to dose reductions. Serious AEs were reported in 73% of patients and 3% experienced AEs that proved fatal (differentiation syndrome, n = 2; hemorrhage, n = 1); sudden death, n = 1).","_key":"f4c350ace4860","_type":"span"}],"_type":"block","style":"normal"},{"_key":"71f58c816a01","markDefs":[],"children":[{"_type":"span","marks":[],"text":"References","_key":"1c8569c3b9a90"}],"_type":"block","style":"h3"},{"markDefs":[],"children":[{"text":"FDA approves revumenib for relapsed or refractory acute leukemia with a KMT2A translocation. FDA. November 15, 2024. Accessed November 15, 2024. https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-revumenib-relapsed-or-refractory-acute-leukemia-kmt2a-translocation","_key":"12a1baf2157e0","_type":"span","marks":[]}],"level":1,"_type":"block","style":"normal","_key":"7a58591a5c07","listItem":"number"},{"_type":"block","style":"normal","_key":"98572eb5a147","listItem":"number","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Revuforj. 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Accessed November 15, 2024. https://ir.syndax.com/news-releases/news-release-details/syndax-announces-fda-approval-revuforjr-revumenib-first-and-only","_key":"c803a86eeb150"}]}],"articleType":"News"},{"url":"what-we-re-reading-concierge-nonprofit-hospitals-kaiser-permanente-elderly-care-program-health-care-not-among-top-voter-issues","_updatedAt":"2024-11-05T13:50:15Z","drugMentions":"{\n \"drug_mentions\": []\n}","updatedOn":"2024-11-05T13:50:12.369Z","articleType":"News","contentCategory":{"_ref":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2","_type":"reference"},"authors":[{"displayName":"AJMC Staff","url":"ajmc-staff"}],"factCheckAuthors":null,"published":"2024-04-01T14:37:05.010Z","audioUrl":"https://s3.us-east-1.amazonaws.com/ai-generated-audios/www.ajmc.com/3cf7bddb-49e5-4567-a52f-4e84196000cc_1730814615828.a1b87dd4-07ad-40f4-b30a-0ac77d252dd4.mp3","summary":"Some nonprofit hospitals now offer concierge physician practices for high-paying patients; Kaiser Permanente partners with investment firms to launch Habitat Health; Gallup data shows a surprising decline in health care's priority ranking.","ExcludeFromPubMedXML":false,"thumbnail":{"_type":"mainImage","alt":"What We’re Reading: Concierge Nonprofit Hospitals; Kaiser Permanente Program for Elderly Care; Health Care Not a Top Issue Among Voters","asset":{"_ref":"image-703de894e882d8a6da8c19964dc1ca71b969d30c-2000x1046-png","_type":"reference"}},"taxonomyMapping":[{"_type":"taxonomy","name":"News","_id":"39be7351-bd4c-4e98-82b3-0d675ae4671b","_updatedAt":"2022-01-19T10:20:16Z","identifier":"news","_createdAt":"2020-03-30T18:05:45Z","parent":null,"_rev":"OU32WOWh4YetHW0RkWbkso"}],"authorMapping":[{"_key":"1275db35f697","_ref":"author_bf191d3321b36496012d9934bdb9a322","_type":"reference"}],"_type":"article","gptSummary":"Nonprofit hospitals are increasingly adopting concierge medicine, charging affluent patients annual fees for enhanced physician access, raising concerns about healthcare equity and access. Meanwhile, Kaiser Permanente's venture, Habitat Health, aims to use the PACE model to provide comprehensive elderly care at home, pending regulatory approval. This initiative could start in Sacramento and Los Angeles by 2025. Additionally, Gallup polls indicate a shift in national priorities, with healthcare dropping in importance post-pandemic, despite its continued relevance amid broader societal challenges.","is_visible":true,"body":[{"children":[{"_type":"span","marks":["strong"],"text":"The Rise of Concierge Medicine in Nonprofit Hospitals","_key":"2ba3333e77da0"}],"_type":"block","style":"normal","_key":"11bba54ca717","markDefs":[]},{"markDefs":[{"nofollow":true,"blank":true,"_type":"link","href":"https://kffhealthnews.org/news/article/concierge-medicine-physician-practices-hospitals-private-equity/","_key":"7218a344873c"}],"children":[{"_type":"span","marks":[],"text":"More nonprofit hospitals have adopted concierge medicine, charging annual fees of $2000 or more to grant affluent patients enhanced access to physicians, ","_key":"e7c385f35b7f0"},{"_type":"span","marks":["7218a344873c"],"text":"according to Kaiser Health News","_key":"e7c385f35b7f1"},{"_type":"span","marks":[],"text":". Although critics have argued this exacerbates primary care shortages and inflates health care costs, hospitals have found financial incentives in attracting wealthy patients and securing referrals. 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Habitat Health will not begin operating as a PACE organization until it receives full approval from CMS and the California Department of Health Care Services; if it does, it could begin its services in Sacramento and Los Angeles in 2025. 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For example, ","_key":"468eb2de053d0"},{"marks":["9db149934e93"],"text":"previous studies used","_key":"9348645311ee","_type":"span"},{"text":" triggers, like death or intensive care unit transfer, to identify patients who may have experienced diagnostic errors.","_key":"468eb2de053d2","_type":"span","marks":[]},{"_type":"span","marks":["superscript"],"text":"2","_key":"cc743ed7bcd3"},{"_type":"span","marks":[],"text":" However, using clinical triggers may introduce hindsight bias, potentially influencing the reported rates of harm associated with diagnostic errors.","_key":"08fddfc3ccde"},{"_type":"span","marks":["superscript"],"text":"1","_key":"c124c1056ac9"}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"a863ea9a85880"}],"_type":"block","style":"normal","_key":"84c6b582ebed"},{"children":[{"_type":"span","marks":[],"text":"Conversely, care transitions represent opportunities for error recognition since the oncoming clinician can ","_key":"12ce08fdc1a30"},{"_type":"span","marks":["49fed914d669"],"text":"review","_key":"12ce08fdc1a31"},{"_key":"12ce08fdc1a32","_type":"span","marks":[],"text":" and reassess the previous clinician’s care."},{"_key":"3940be7ccaad","_type":"span","marks":["superscript"],"text":"3"},{"marks":[],"text":" Consequently, the researchers aimed to develop a program to leverage end-of-week clinician care transitions to identify diagnostic errors and possible causes in hospitalized patients.","_key":"ee64d3221ed4","_type":"span"},{"_type":"span","marks":["superscript"],"text":"1","_key":"00fba6bbff82"}],"_type":"block","style":"normal","_key":"0c2225cae2aa","markDefs":[{"_type":"link","href":"https://shmpublications.onlinelibrary.wiley.com/doi/10.12788/jhm.3262","_key":"49fed914d669","nofollow":true,"blank":true}]},{"_type":"figure","disableLightBox":true,"alt":"Clinician giving patient a diagnosis | Image Credit: Pcess609 - stock.adobe.com","_key":"5486307e9e3d","alignment":"right","widthP":39,"imgcaption":[{"style":"normal","_key":"70da6e1a9c19","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Examining care transitions in hospitalized patients revealed lower diagnostic error rates compared to traditional methods. | Image Credit: Pcess609 - stock.adobe.com","_key":"b1fdba2fd53f0"}],"_type":"block"}],"asset":{"_ref":"image-70a41b427e3ba8b6d6044d291f38bd6f75f8945a-5107x3404-jpg","_type":"reference"},"disableTextWrap":false},{"_type":"block","style":"normal","_key":"3155fc8a729e","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Therefore, the researchers conducted a single-center study at Northwestern University, an 897-bed teaching hospital, from April 2019 to August 2021. 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A study at Northwestern University found a lower prevalence of diagnostic errors using this approach compared to previous methods. The study identified missed information from electronic health records as the most common error cause. Although the study had limitations, such as being single-site, it suggests that leveraging care transitions can offer a feasible and potentially more precise method for identifying diagnostic errors in hospital settings.","drugMentions":"{\"drug_mentions\": []}","updatedOn":"2024-10-24T17:53:00.000Z","audioUrl":"https://s3.us-east-1.amazonaws.com/ai-generated-audios/www.ajmc.com/2d5629d7-c4a4-4207-9c55-ac0b26c16a9c_1729540201486.dec9c459-88de-4221-a317-421f74d982af.mp3","ExcludeFromPubMedXML":false,"_type":"article","articleType":"News","is_visible":true,"gptTakeaways":"• Care transitions offer a more accurate method for identifying diagnostic errors compared with traditional clinical triggers.\n\n• The study found a lower prevalence of diagnostic errors, with missed electronic health record information being the most common cause.\n\n• Few diagnostic errors were associated with harm, and most involved infectious, cardiovascular, and neurologic conditions.\n\n• The study's single-site nature and varying transition practices across hospitals limit generalizability, but findings remain promising.","authors":[{"displayName":"Brooke McCormick","url":"brooke-mccormick"}]},{"body":[{"style":"normal","_key":"2b340d371209","markDefs":[],"children":[{"_key":"42e8009116d80","_type":"span","marks":[],"text":"Making sure that patients can receive health care is of vital importance when natural disaster is on the horizon. With hurricane season fast approaching the states bordering the Gulf of Mexico and Atlantic Ocean, health care professionals need to prepare for treating patients who may not be able to access health care for an indeterminate amount of time. Collaboration and preparation among multiple teams is of paramount importance to addressing natural disasters when it comes to health care."}],"_type":"block"},{"style":"normal","_key":"2332b789a869","markDefs":[],"children":[{"_key":"8c25fef1e6460","_type":"span","marks":[],"text":""}],"_type":"block"},{"children":[{"text":"The period from June through December is usually regarded as hurricane season in the Atlantic Ocean and acts as the primary natural disaster that affects the east and southeastern coasts. Hurricanes can leave residents stranded without means of receiving their health care due to flooding, structural damage to their home, or downed trees and cable lines that make streets dangerous to drive on, assuming the patient has a means of transportation at all. According to an article from Texas A\u0026M, it is estimated that only 35% of people in South Carolina who were recommended to evacuate for Hurricane Matthew in 2016 actually left their home.","_key":"0224ef158c700","_type":"span","marks":[]},{"_key":"b68adf7a6233","_type":"span","marks":["superscript"],"text":"1"},{"_type":"span","marks":[],"text":" This can leave a significant number of people in vulnerable situations once a hurricane actually hits, and can lead to a greater number of fatalities.","_key":"948c7db1b403"}],"_type":"block","style":"normal","_key":"ea20207528cb","markDefs":[]},{"_key":"b3a18afe8c82","markDefs":[],"children":[{"marks":[],"text":"With so many people likely to be vulnerable, not only to the after effects of the hurricane itself but also when it comes to getting the health care and treatments that they need, with a 33% higher death rate following a hurricane due to contributing factors,","_key":"82b2ce33a1060","_type":"span"},{"text":"2","_key":"159c713914db","_type":"span","marks":["superscript"]},{"_type":"span","marks":[],"text":" it is important that health care officials, government, and health care facilities work together to figure out ways to address the needs of as many people as possible.","_key":"e04443fedd81"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Oncology Practices’ Preparations","_key":"be073c97c685"}],"_type":"block","style":"h3","_key":"e4de6eb3f3ac"},{"style":"normal","_key":"5067acabf8c6","markDefs":[],"children":[{"marks":[],"text":"After Hurricane Helene moved through the Southeastern US in late September, bringing devastating flooding, Chris Elder, PharmD, BCOP, associate director of pharmacy clinical services at Florida Cancer Specialists \u0026 Research Institute, told ","_key":"588430fad03f","_type":"span"},{"_key":"0937b9e3dad1","_type":"span","marks":["em"],"text":"The American Journal of Managed Care"},{"text":"®","_key":"5dfce5c63d66","_type":"span","marks":["superscript"]},{"_type":"span","marks":[],"text":" (","_key":"d2303c934d4c"},{"_type":"span","marks":["em"],"text":"AJMC®","_key":"3c6ff1fc8489"},{"_key":"479f9c8a3fc5","_type":"span","marks":[],"text":") that hurricanes can be hard to prepare for because even if staff know that the storm is coming, fear of the storm is something that both patients and staff have to overcome. Creating proper plans and preparing for the storm is the best form of overcoming that fear."}],"_type":"block"},{"_type":"block","style":"normal","_key":"b9ceedaa3edc","markDefs":[],"children":[{"_type":"span","marks":[],"text":"\"That [emergency prep] team is getting together and meeting well in advance of a storm actually coming and walking through strategies and making sure teams are in place,\" said Elder. \"Everyone has their roles established and what they're accountable for, really to help minimize an impact. So that's really our goal: protecting our patients, protecting our staff, as well as our assets, our buildings, and our medications we have stored on site.\"","_key":"4fb0c5f4a482"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Darrin Owen, pharmacy operations solutions manager at Florida Cancer Specialists \u0026 Research Institute, said that emergency operations plans start to form even before the 96-hour mark, as hurricanes can sometimes make unexpected turns that leave different parts of the state affected compared with what was planned. Generator clinics and battery backups act as assurance to keeping the stock within the clinics safe and prevent them from perishing.","_key":"35445961b025"}],"_type":"block","style":"normal","_key":"da7baa472c95"},{"_type":"block","style":"normal","_key":"c3ec0a71fa13","markDefs":[],"children":[{"_type":"span","marks":[],"text":"\"We have plans in place for our clinics that do not have generators to transfer their drugs to these locations so we know these drugs are safe during the storm,\" Owen told ","_key":"e0e72fa3f084"},{"marks":["em"],"text":"AJMC","_key":"234b0d45caad","_type":"span"},{"_type":"span","marks":[],"text":". \"We won't delay patient care once we're able to assess damage and contact patients and get them back into the clinics.\"","_key":"57ce4f07afa7"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Owen emphasized that oncology clinics, such as the one he works in, work together with multiple departments within their organization to get patients to their closest clinic to receive their treatment. The ability to move drugs from one place to another is also a beneficial practice in these situations.","_key":"133d7d2030cb"}],"_type":"block","style":"normal","_key":"7d9319d23cd4"},{"_key":"f3b223c8e821","markDefs":[],"children":[{"_type":"span","marks":[],"text":"\"This past hurricane [Helene], we had a list of drugs that FedEx and UPS had a no-ship zip list so we knew where drugs weren't going to be able to be delivered,\" he said. \"So in an event like that, we can always plan to have it delivered to a different zip code so that way we can get someone to go to that location, pick up the medication, and bring it to wherever we can get the patient.\"","_key":"7bd1eb12b64e"}],"_type":"block","style":"normal"},{"children":[{"_type":"span","marks":[],"text":"Elder stated that, with Hurricane Helene, about 70% of clinics were open on Thursday and all returned to fully operational by Monday due to the preparation put in before each hurricane. However, Elder emphasized that they want to make sure patients are not putting themselves in danger when attempting to get to a clinic to get their treatment, stating that patients are often more fearful of the storm than they are about missing treatments.","_key":"b01636295eb1"}],"_type":"block","style":"normal","_key":"192184ea7cf6","markDefs":[]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"\"We need to empathize with that, recognize that fear that patients may have, and communicate effectively and appropriately to let them know that it's more important that they stay safe and may, at the very worst case, miss a day or so of treatment vs being placed in a dangerous scenario,\" said Elder. \"We want to protect the patients, keep them safe, keep them on schedule as much as we can...but knowing if we need to move them a few days out, that's not going to impact their care.\"","_key":"0427d521d8c8"}],"_type":"block","style":"normal","_key":"2d6774a1d66c"},{"markDefs":[],"children":[{"_key":"3cd495c36579","_type":"span","marks":[],"text":"Strategies for the Underserved"}],"_type":"block","style":"h3","_key":"a1b56f19b8ce"},{"style":"normal","_key":"7d3b5e6e71c3","markDefs":[],"children":[{"text":"Federally qualified health centers (FQHCs) and other clinics that provide care throughout the country are an important resource when it comes to helping patients in low-income areas. FQHCs and other clinics can give extended supplies of medications to their patients to ensure that their patients have enough to last through the natural disaster, even providing methods of keeping perishable medications cool in case of a power outage.","_key":"0f741a24d05d","_type":"span","marks":[]},{"marks":["superscript"],"text":"2","_key":"c303678b8fea","_type":"span"},{"_type":"span","marks":[],"text":" ","_key":"65b5d4613a27"}],"_type":"block"},{"style":"normal","_key":"87e03d866ddf","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Other methods of making sure patients can maintain contact with their providers included distributing smartphones and remote monitoring tools for patients in the area to ensure the patient is able to request help if they need it. The clinics can also help serve patients that are not their own in case of flooding and other emergencies.","_key":"a46e574afea6"}],"_type":"block"},{"children":[{"_type":"span","marks":[],"text":"Another aspect of care that the FQHCs specifically can address is the care of undocumented immigrants during these emergencies. Undocumented immigrants are less likely to go to clinics for care during emergencies due to a fear of deportation. FQHC staff can attempt travel to areas with the most need in order to encourage patients to get care and give care themselves in order to care for the patients as quickly and effectively as possible.","_key":"07592c0248690"},{"_type":"span","marks":["superscript"],"text":"2","_key":"28db560a946f"}],"_type":"block","style":"normal","_key":"8ee7c4c678a1","markDefs":[]},{"_type":"block","style":"h3","_key":"68f5c055342d","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Keeping Hospitals Safe","_key":"758b25e9d96e"}]},{"style":"normal","_key":"5a791059f87d","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Hospitals also act as facilities that have to prepare for natural disaster. All hospitals require an emergency plan in case of disaster, approved by the hospital’s accrediting body.","_key":"5613c273c2020"},{"_type":"span","marks":["superscript"],"text":"3","_key":"f425f30ec760"},{"_type":"span","marks":[],"text":" These plans are implemented before natural disasters such as hurricanes, with coordination occurring between local government, first responders, and patients. Decisions include deciding whether to evacuate the hospital or have staff remain the hospital throughout the storm. However, transferring patients can have health consequences so these decisions are not taken lightly and are done only in extreme emergencies.","_key":"b9dfc5971cce"}],"_type":"block"},{"style":"normal","_key":"3e770c1a8cce","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Right before natural disasters, patients needing elective surgery will have to wait, as these surgeries are often shut down in favor of utilizing resources solely on disaster relief and taking care of patients already admitted to the hospital.","_key":"1e24e30bd40f0"},{"marks":["superscript"],"text":"3","_key":"9382c5f0a91e","_type":"span"},{"_type":"span","marks":[],"text":" This includes making sure that there are 2 teams of health care professionals available to treat patients and able to relieve each other of work.","_key":"4aa7b43c3fb6"}],"_type":"block"},{"style":"normal","_key":"54205f2639ae","markDefs":[],"children":[{"text":"Emergency plans for hurricanes include making sure that there is air conditioning for patient comfort, backup power for equipment keeping patients alive, and having enough food, water, and medicine in case of supply chain issues or difficulty in getting supplies to the hospital. This is vital when it comes to continuing to care for the patients within the care of the hospital.","_key":"e79c7ce1d5bc0","_type":"span","marks":[]}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"\"Knowing that [hurricanes] are eventually going to happen during hurricane season for us, it's always best to have a plan in place,\" said Owen. \"We know, in most cases, health care providers and patients are most likely to be displaced after natural disaster, so it's in our best interest to be prepared for them and have a solution ready.\"","_key":"0a8effd81dd8"}],"_type":"block","style":"normal","_key":"a7aa433ac922"},{"_key":"b821fa94b5d1","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Looking Forward","_key":"3b4d750b12e80"}],"_type":"block","style":"h3"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"An important factor when considering preparation in the future is the effect of climate change when it comes to both the extremity of the storms as well as the frequency of the storms. This can include the rising sea level or more frequent wildfires in some areas that can affect the way that residential patients live. Patients who are at a higher risk of being effected by extreme weather events were identified through a dashboard created in 2021.","_key":"1c7b549545e40"},{"marks":["superscript"],"text":"2","_key":"165b8c1d808d","_type":"span"},{"_type":"span","marks":[],"text":" This dashboard includes patients who have cancer, asthma, chronic obstructive pulmonary disease, dementia, and mental illness. The dashboard is able to indicate which regions are most at risk by assessing weather, climate, and air quality data in each region. This can allow for health centers and providers to narrow down who they need to target when it comes to preparation.","_key":"bc5c61294fe6"}],"_type":"block","style":"normal","_key":"2c222a1719f1"},{"imgcaption":[{"_key":"61de1fc1d586","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Hospitals, clinics, and health care workers prepare for hurricanes in advance to make sure all patients receive the care that they need | Image credit: Satoshi Kina - stock.adobe.com","_key":"1c8102a63b740"}],"_type":"block","style":"normal"}],"_key":"c0535201fc63","alignment":"right","disableTextWrap":false,"alt":"Hospitals, clinics, and health care workers prepare for hurricanes in advance to make sure all patients receive the care that they need | Image credit: Satoshi Kina - stock.adobe.com","asset":{"_ref":"image-6f6723ca96a1ccfd82d7c53cfb0a53bb6f6a2685-6708x4472-jpg","_type":"reference"},"widthP":40,"disableLightBox":true,"_type":"figure"},{"style":"normal","_key":"fd1ce511610b","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Climate change is also likely to affect areas of low health equity, due to poorer air quality and lower funding in the area. Targeting these areas as regions to focus on during and outside of natural disasters should be a priority going forward, as reducing the disparities found in these areas could improve overall mortality and strain on health care resources during natural disasters.","_key":"2b720a0503fb0"}],"_type":"block"},{"children":[{"_type":"span","marks":[],"text":"","_key":"14683fec99ea"}],"_type":"block","style":"normal","_key":"c06bad989c2a","markDefs":[]},{"children":[{"_type":"span","marks":[],"text":"Elder stated that making sure that all clinics in the state are prepared for the storm, regardless of whether they initially think the storm will affect them or not, is a way for them to keep vigilant and take all of the hurricanes seriously.","_key":"cd8dc004bd81"}],"_type":"block","style":"normal","_key":"a4b3e81307f6","markDefs":[]},{"markDefs":[],"children":[{"_key":"2488b2b4ddc1","_type":"span","marks":[],"text":""}],"_type":"block","style":"normal","_key":"692eecf1efcc"},{"_key":"e53af4cc38bd","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Owen addressed this by saying that, for them, the severity of the future hurricanes doesn't materially affect the way that they will prepare for hurricanes in the future. \"We may have to pivot based off of different outliers with the storm...But I really feel that if we just continue moving forward with the plan that we have in place, in improving that plan, I think that's the most we can do,\" he said.","_key":"2131fd4705b3"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"28a38d39f26c","markDefs":[],"children":[{"text":"","_key":"f1fcb4656110","_type":"span","marks":[]}]},{"style":"normal","_key":"f753d70e43c5","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Elder said that there are aspects of emergency planning and disaster preparation that can help in day-to-day medical treatment, including effective communication, strategic planning, establishing accountability, and establishing clear roles and responsibilities. ","_key":"ef8dabca839f"}],"_type":"block"},{"_key":"f35a1ac2476d","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"2bb809872be2"}],"_type":"block","style":"normal"},{"children":[{"marks":[],"text":"\"As we know, unfortunately we go through storm season every year and we just had Hurricane Helene. We're already on the lookout for the next storm coming. So any way that we can make improvements will be beneficial,\" said Elder. \"So being able to take those processes and key strategies, we can apply those to the day to day operations to streamline care and be even more effective in delivering cancer care to our patients.\"","_key":"c689a200f909","_type":"span"}],"_type":"block","style":"normal","_key":"98abfdacb30b","markDefs":[]},{"_key":"0741cf913d0a","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"9356bfcae116"}],"_type":"block","style":"normal"},{"style":"normal","_key":"e90f9e3979ff","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Improving on their plans, according to Owen, could involve doing more outreach in the days following a hurricane, specifically the idea of mobile units being dispatched that could help to administer medication. Pop-up areas around a community could be 1 such option. \"If we could come across something like that in the future to help with this, I think it would definitely improve patient care...During times like this, FEMA goes out and they do their pop-up things for just regular assistance. I could see health care helping with something like that as well,\" he said.","_key":"f8dfdf5d251d"}],"_type":"block"},{"_type":"block","style":"normal","_key":"e164514fd535","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"2943b454d98b0"}]},{"markDefs":[],"children":[{"text":"Overall, a great deal of preparation is required to get the proper mechanizations in place to care for patients during a natural disaster. Preparing patients by giving them extra supplies of necessary medication, addressing patients who have stayed during a call for evacuation, and helping patients who live in particular areas of need are paramount in making sure that natural disasters do not worsen the health care of patients in affected areas.","_key":"bbee72f3ec6a0","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"12017b284804"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"618f0922e54d0"}],"_type":"block","style":"normal","_key":"1218e0c19238"},{"style":"normal","_key":"fa98b049767a","markDefs":[],"children":[{"text":"References","_key":"ece070d7ee560","_type":"span","marks":["strong"]}],"_type":"block"},{"listItem":"number","markDefs":[],"children":[{"text":"Horney J. Why don’t more people evacuate before hurricanes? Texas A\u0026M Today. October 19, 2016. Accessed September 25, 2024. https://today.tamu.edu/2016/10/19/why-dont-more-people-evacuate-before-hurricanes/","_key":"a86bc96b11870","_type":"span","marks":[]}],"level":1,"_type":"block","style":"normal","_key":"4e9d3ac3dae3"},{"_key":"e9f23b6f775b","listItem":"number","markDefs":[],"children":[{"marks":[],"text":"Hostetter M, Klein S. How health care organizations are preparing for climate shocks and protecting vulnerable patients. The Commonwealth Fund. October 20, 2022. Accessed September 25, 2024. https://www.commonwealthfund.org/publications/2022/oct/how-health-care-organizations-are-preparing-for-climate-shocks","_key":"4d53a72d283a0","_type":"span"}],"level":1,"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"d551ee8734dc","listItem":"number","markDefs":[],"children":[{"marks":[],"text":"Hess DB. How do hospitals prepare for hurricanes. CNN Health. September 2, 2019. Accessed September 25, 2024. https://www.cnn.com/2019/09/02/health/hurricane-hospital-prep-partner/index.html","_key":"a06fde1d5e5f0","_type":"span"}],"level":1}],"title":"Addressing Natural Disaster Takes Cooperation, Preparation to Ensure Patient Health","factCheckAuthors":null,"articleType":"News","_updatedAt":"2024-10-01T15:09:28Z","thumbnail":{"_type":"mainImage","alt":"Hurricane | Image credit: Satoshi Kina - stock.adobe.com","caption":"Hurricane | Image credit: Satoshi Kina - stock.adobe.com","asset":{"_ref":"image-6f6723ca96a1ccfd82d7c53cfb0a53bb6f6a2685-6708x4472-jpg","_type":"reference"}},"_rev":"LKAfGsMVtGrsTVLa39eCw1","contentCategory":{"_ref":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2","_type":"reference"},"authorMapping":[{"_type":"reference","_key":"b647ef184b67","_ref":"15b1de57-6a71-4655-ba17-eeaa1c733634"}],"is_visible":true,"_type":"article","taxonomyMapping":[{"name":"News","_id":"39be7351-bd4c-4e98-82b3-0d675ae4671b","_updatedAt":"2022-01-19T10:20:16Z","parent":null,"identifier":"news","_createdAt":"2020-03-30T18:05:45Z","_rev":"OU32WOWh4YetHW0RkWbkso","_type":"taxonomy"},{"_createdAt":"2020-04-14T19:36:49Z","_rev":"oStaF2be7QCQWMYKlMllhH","_type":"taxonomy","name":"Health System","_id":"c299e541-89d0-456b-8b2a-4cb16235097b","_updatedAt":"2021-08-19T07:15:06Z","identifier":"health-system","parent":{"identifier":"stakeholders","_createdAt":"2020-04-14T19:35:35Z","_rev":"OP7H2echeMthIUyBlewe80","_type":"taxonomy","name":"Stakeholders","_id":"5aa8e7d5-8a2d-44dd-99fc-fc43f03e2bed","parent":null,"_updatedAt":"2022-02-18T12:19:28Z"}},{"_updatedAt":"2022-11-29T18:34:57Z","identifier":"healthcare-delivery","parent":{"identifier":"topic","_createdAt":"2020-03-31T14:24:50Z","_rev":"SpZIJtjiAn4ebHE4u6sWYc","isMainTopic":true,"parent":null,"_type":"taxonomy","name":"Topic","_id":"15012229-f713-4f0a-8f82-7667530bb382","_updatedAt":"2021-10-21T10:15:35Z"},"_createdAt":"2020-05-04T23:46:13Z","_rev":"52vAUxG62nnEnK65ZDo5dG","_type":"taxonomy","name":"Health Care Delivery","_id":"topic_healthcare-delivery"}],"published":"2024-09-26T14:29:00.000Z","_createdAt":"2024-09-25T17:29:29Z","summary":"As hurricane season approaches, doctors, pharmacists, and clinics prepare for treating their patients when accessibility is limited.","_id":"918e6b39-9d36-462d-ad70-f3693f03e0d3","seoTag":["hurricane","natural disaster","preparation"],"authors":[{"displayName":"Julia Bonavitacola","url":"julia-bonavitacola"}],"ExcludeFromPubMedXML":false,"updatedOn":"2024-10-01T14:29:49.147Z","url":"addressing-natural-disaster-takes-cooperation-preparation-to-ensure-patient-health"},{"thumbnail":{"_type":"mainImage","alt":"Opdivo packaging | Image credit: Bristol Myers Squibb","caption":"Opdivo packaging | Image credit: Bristol Myers Squibb","asset":{"_ref":"image-020de2a739acebd5b1504eaae11472ee817989eb-880x588-webp","_type":"reference"}},"factCheckAuthors":null,"contentCategory":{"_ref":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2","_type":"reference"},"_createdAt":"2024-05-09T14:12:09Z","articleType":"News","summary":"Some experts believe offering a subcutaneous version of nivolumab could make PD-1 inhibitors available to new groups of patients who currently lack access, such as those in rural areas.","_type":"article","url":"fda-accepts-nivolumab-subcutaneous-injection-application-with-potential-to-boost-access-to-pd-1-inhibitors","title":"FDA Accepts Nivolumab Subcutaneous Injection Application, With Potential to Boost Access to PD-1 Inhibitors","ExcludeFromPubMedXML":false,"body":[{"markDefs":[],"children":[{"text":"This article has been updated to reflect a revised target action date.","_key":"3d1048e4c5c30","_type":"span","marks":["em"]}],"_type":"block","style":"normal","_key":"41703c5983b8"},{"_type":"block","style":"normal","_key":"7f370f4ff381","markDefs":[],"children":[{"_key":"7f7ef136297e","_type":"span","marks":[],"text":"FDA has accepted Bristol Myer Squibb’s biologics license application (BLA) for its subcutaneous (SC) formulation of the nivolumab, which company officials say has the “potential” to be the first PD-1 inhibitor administered by subcutaneous injection if approved by its target action date, which has been advanced to December 29, 2024."},{"_type":"span","marks":["superscript"],"text":"1,2","_key":"5e1ac0420814"}]},{"_key":"18e69fbb5220","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Sold as Opdivo, the therapy is formulated with hyaluronidase to create subcutaneous (SC) nivolumab. According to a BMS statement, the BLA covers all previously approved indications for use of intravenous (IV) nivolumab as a monotherapy in adult solid tumors, and all approvals for monotherapy as a maintenance therapy following use of the combination nivolumab plus ipilimumab (Yervoy) or combinations with chemotherapy or cabozantinib (Cabometyx).","_key":"982e953e0bc9"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Although some warn it’s too soon to say whether the shift to SC nivolumab will be a game-changer, leaders from BMS are enthusiastic about the BLA.","_key":"1a9e7e7466fa"}],"_type":"block","style":"normal","_key":"3d5f65f07a1c"},{"_key":"478d53c3a3cf","alignment":"left","asset":{"_ref":"image-0e20514b3f4fc8c570e965e47c4c6f01add5d233-500x500-jpg","_type":"reference"},"widthP":15,"_type":"figure","alt":"Gina Fusaro, PhD | Image credit: LinkedIn","imgcaption":[{"_type":"block","style":"normal","_key":"e144f8a21dc0","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Gina Fusaro, PhD | Image credit: LinkedIn","_key":"51e126ab2c89"}]}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"“We believe subcutaneous nivolumab has the potential to make a significant difference in the lives of patients, which is reinforced by the FDA’s acceptance of our application,” Gina Fusaro, PhD, vice president, global program lead, BMS, said in the statement. “[Nivolumab] is a foundational PD-1 inhibitor approved for many different types of cancer, and our continued investment in research that puts patients first remains a priority.","_key":"5f1970eb80770"},{"_key":"27ad0cd7acc5","_type":"span","marks":["superscript"],"text":"2"}],"_type":"block","style":"normal","_key":"07542976be2c"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"80e54e1627200"}],"_type":"block","style":"normal","_key":"e3d1c66b344e"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"“If approved by the FDA, the subcutaneous administration of nivolumab would provide patients and their physicians with a new option that delivers the same well-known benefits as IV [nivolumab] but with the improved convenience of an injection administered in 3-5 minutes rather than a 30-to-60-minute infusion.”","_key":"8f5a196ce910"},{"text":"2","_key":"05c892576860","_type":"span","marks":["superscript"]}],"_type":"block","style":"normal","_key":"9735bb9abae7"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The BLA is based on results from CheckMate-67T (NCT04810078), a phase 3 randomized trial that compared SC nivolumab and IV nivolumab in patients with advanced or metastatic clear cell renal cell carcinoma who had received prior systemic therapy. A total of 495 patients were evaluated. Coprimary endpoints are time-averaged serum concentration over 28 days and trough serum concentration at steady-state of SC nivolumab vs IV nivolumab. 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Accessed May 6, 2024. https://news.bms.com/news/details/2024/U.S.-Food-and-Drug-Administration-Accepts-Bristol-Myers-Squibbs-Application-for-Subcutaneous-Nivolumab-nivolumab-and-hyaluronidase/default.aspx","_key":"cdbba63c3806"}],"_type":"block","style":"normal","_key":"bb16c3871a55","markDefs":[]},{"style":"normal","_key":"32059f310c10","markDefs":[{"_key":"0e45310abdd0","_type":"link","href":"https://www.cancer.gov/news-events/cancer-currents-blog/2024/kidney-cancer-subcutaneous-nivolumab"}],"children":[{"text":"3. George S, Bourlon MT, Chacon MR, et al. Subcutaneous nivolumab (NIVO SC) vs intravenous nivolumab (NIVO IV) in patients with previously treated advanced or metastatic clear cell renal cell carcinoma (ccRCC): pharmacokinetics (PK), efficacy, and safety results from CheckMate 67T. 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The study utilized data from the Canadian Longitudinal Study on Aging, Busselton Healthy Aging Study, and UK Biobank, revealing that PRS significantly explained variance in IOP and VCDR phenotypes. However, the PRS was less predictive in non-European ancestries, indicating a need for further research in diverse populations. The findings suggest PRS could improve early glaucoma diagnosis and management strategies.","timeAgo":107900.283,"authors":[{"displayName":"Julia Bonavitacola","url":"julia-bonavitacola"}],"_updatedAt":"2024-11-22T21:58:57Z","url":"polygenic-risk-scores-can-identify-patients-who-should-receive-iop-lowering-treatment","authorMapping":[{"_type":"reference","_key":"e61c5123dda5","_ref":"15b1de57-6a71-4655-ba17-eeaa1c733634"}],"_type":"article","drugMentions":"{\"drug_mentions\": []}","seoTag":["IOP","PRS","VCDR","glaucoma"],"gptTakeaways":"• Polygenic risk scores for IOP and VCDR significantly enhance glaucoma risk prediction, especially for primary open-angle glaucoma.\n\n• The study utilized data from multiple cohorts, including the Canadian Longitudinal Study on Aging and UK Biobank.\n\n• PRS explained a substantial variance in IOP and VCDR phenotypes, improving prediction accuracy.\n\n• The PRS was less effective in non-European ancestries, highlighting the need for further research in diverse populations.","published":"2024-11-21T16:00:36.717Z","_createdAt":"2024-11-21T15:50:34Z","body":[{"markDefs":[{"nofollow":false,"blank":true,"_type":"link","href":"https://www.ajmc.com/compendium/ophthalmology","_key":"604440543c88"}],"children":[{"_type":"span","marks":[],"text":"An intraocular pressure (IOP) polygenic risk score (PRS) could identify which patients would benefit the most from intensive treatment to lower IOP and manage their risk of ","_key":"452f402cbf7c0"},{"_type":"span","marks":["604440543c88"],"text":"glaucoma","_key":"7cab263ba064"},{"_type":"span","marks":[],"text":", according to a study published in ","_key":"96920c6afff6"},{"_type":"span","marks":["em"],"text":"JAMA Ophthalmology","_key":"452f402cbf7c1"},{"text":".","_key":"452f402cbf7c2","_type":"span","marks":[]},{"_type":"span","marks":["superscript"],"text":"1","_key":"4e352fba678a"},{"marks":[],"text":" Vertical cup-disc ratio (VCDR) PRS can also be used to determine the risk of glaucoma, even in patients with normal IOP.","_key":"89d377a2c056","_type":"span"}],"_type":"block","style":"normal","_key":"a27a6e39826f"},{"_type":"block","style":"normal","_key":"ca039f74e1da","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"a2939c2dff270"}]},{"_type":"block","style":"normal","_key":"47bdcc617935","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Glaucoma is an eye condition that can lead to vision loss and blindness, with the most prevalent form of glaucoma being primary open-angle glaucoma (POAG)","_key":"a598eba7d7370"},{"_type":"span","marks":["superscript"],"text":"2","_key":"8cec5a3509a5"},{"_type":"span","marks":[],"text":" at 2.4% global prevalence. IOP and VCDR are 2 of the risk factors for POAG and are necessary in attempting to diagnose the condition early to prevent the worst outcomes in patients. Due to the heritability of IOP and VCDR, a PRS could be beneficial in identifying individuals who are most at risk. This study aimed to assess how PRS can help to identify patients who are at highest risk based ont heir OP and VCDR scores.","_key":"f0107a68c1b4"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"2954d48a54090"}],"_type":"block","style":"normal","_key":"3840269b9a63"},{"style":"normal","_key":"6d7f3835e6ed","markDefs":[],"children":[{"_type":"span","marks":[],"text":"This study used multiple cohorts from previous studies, including the Canadian Longitudinal Study on Aging (CLSA), the Busselton Healthy Aging Study (BHAS) and the UK Biobank. The CLSA contained data from Canadians aged between 45 and 85 years collected between 2010 and 2015. IOP measurements that compensated for the cornea were calculated for baseline and follow-up in this dataset. Any participant who did not have IOP measurements was excluded.","_key":"71ad2ac800fa0"}],"_type":"block"},{"widthP":40,"alt":"A PRS may be able to predict the incidence of glaucoma in individuals, allowing for more targeted treatment for these patients | Image credit: Alessandro Grandini - stock.adobe.com","_key":"8ce074520216","_type":"figure","imgcaption":[{"_key":"26d84f7005ea","markDefs":[],"children":[{"text":"A PRS may be able to predict the incidence of glaucoma in individuals, allowing for more targeted treatment for these patients | Image credit: Alessandro Grandini - stock.adobe.com","_key":"682c7441c1840","_type":"span","marks":[]}],"_type":"block","style":"normal"}],"asset":{"_ref":"image-b20a6f121504080b81c7aaef4069db75606e501c-4415x2077-jpg","_type":"reference"},"disableTextWrap":false,"disableLightBox":true,"alignment":"left"},{"_type":"block","style":"normal","_key":"3a9b9e46d9e4","markDefs":[],"children":[{"text":"The BHAS included participants from Busselton, Western Australia, with data collected from individuals aged 46 to 64 years between 2010 and 2015. There were 4839 individuals for IOP PRS validation and 1588 individuals who had VCDR PRS validation. The UK Biobank was also used for this study and collected data on individuals aged 40 to 69 years from 2006 to 2010 who lived in the UK. Patients with African, East Asian, and South Asian ancestry were included.","_key":"30814a63e47f0","_type":"span","marks":[]}]},{"markDefs":[],"children":[{"marks":[],"text":"","_key":"f6e0e895f80c0","_type":"span"}],"_type":"block","style":"normal","_key":"cb95fda56133"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"There were 5890 samples from the CLSA used to assess the association between VCDR and IOP and PRS. The researchers found that the baseline model accounted for 3.8% (95% CI, 2.9-4.8) of the variance in unadjusted VCDR and 2.5% (95% CI, 1.8-3.4) in adjusted VCDR. The new PRS was able to explain 22.0% (95% CI, 20.1-23.9) of the variance in phenotypes within the adjusted VCDR and 21.9% (95% CI, 20.1-23.8) in the unadjusted VCDR, both in the CLSA dataset. Variance in phenotypes for IOP was also able to be explained at a rate of 12.9% (95% CI, 11.3-14.6). A total of 3.1% (95% CI, 2.3-4.0) of the variance in phenotypes was accounted for in the baseline model.","_key":"f5f452e25bfb0"}],"_type":"block","style":"normal","_key":"0ccfcb5e774f"},{"style":"normal","_key":"a5736b4dd160","markDefs":[],"children":[{"_key":"33c845647c800","_type":"span","marks":[],"text":""}],"_type":"block"},{"style":"normal","_key":"02c8c8603bf2","markDefs":[],"children":[{"marks":[],"text":"There were 1588 samples in the BHAS dataset that were used to perform a PRS validation. The variance was explained in 0.98% (95% CI, 0.3-2.2) of the adjusted VCDR and 0.79% (95% CI, 0.2-1.9) of the unadjusted VCDR. The PRS was able to explain 19.7% of the variance and 18.3% of the variance in adjusted and unadjusted VCDR respectively. The IOP PRS was able to explain 9.6% of the variance in phenotype.","_key":"930813125b9a0","_type":"span"}],"_type":"block"},{"_key":"caaba898e18a","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"0c9b75272a210"}],"_type":"block","style":"normal"},{"_key":"dda6d5f007f3","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Using the UK Biobank, the VCDR PRS variance explained in 5.2%, 12.1%, and 14.3% for African, East Asian, and South Asian populations, respectively; IOP PRS variance explained 2.3%, 3.2%, and 7.5% in those same populations.","_key":"46d4c2f6522f0"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"213a552c37af","markDefs":[],"children":[{"marks":[],"text":"","_key":"04a78f2b647b0","_type":"span"}]},{"style":"normal","_key":"50dc4c8a5683","markDefs":[],"children":[{"_key":"e0deafb898610","_type":"span","marks":[],"text":"There were some limitations to this study. The PRS was drawn from samples of individuals with European ancestry and was less predictive in people without European ancestry because of this. Future studies for African individuals may be needed in this field to account for differences in IOP in this subgroup. These results have also not affected clinically relevant outcomes for glaucoma."}],"_type":"block"},{"_key":"c64585f13b1b","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"4e0e4b3f8a4c0"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"728778586a7f","markDefs":[],"children":[{"text":"The researchers concluded that a new PRS based on the latest genome-wide association studies, which was able to predict VCDR or IOP more accurately compared with previous data. 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