Bayesian Meta-Analysis to Account for Heterogeneity in Studies Relating Life Events to Disease

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Account for Heterogeneity in Studies Relating Life Events to Disease</title> <meta name="description" content="Bayesian Meta-Analysis to Account for Heterogeneity in Studies Relating Life Events to Disease"> <meta name="keywords" content="Random-effects, meta-analysis, Bayesian, variation."> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <meta name="citation_title" content="Bayesian Meta-Analysis to Account for Heterogeneity in Studies Relating Life Events to Disease"> <meta name="citation_author" content="Elizabeth Stojanovski"> <meta name="citation_publication_date" content="2018/10/01"> <meta name="citation_journal_title" content="International Journal of Mathematical and Computational Sciences"> <meta name="citation_volume" content="12"> <meta name="citation_issue" content="11"> <meta name="citation_firstpage" content="231"> <meta name="citation_lastpage" content="234"> <meta 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class="card-text"><strong>Abstract:</strong></p> <p>Associations between life events and various forms of cancers have been identified. The purpose of a recent random-effects meta-analysis was to identify studies that examined the association between adverse events associated with changes to financial status including decreased income and breast cancer risk. The same association was studied in four separate studies which displayed traits that were not consistent between studies such as the study design, location, and time frame. It was of interest to pool information from various studies to help identify characteristics that differentiated study results. Two random-effects Bayesian meta-analysis models are proposed to combine the reported estimates of the described studies. The proposed models allow major sources of variation to be taken into account, including study level characteristics, between study variance and within study variance, and illustrate the ease with which uncertainty can be incorporated using a hierarchical Bayesian modelling approach.</p> <iframe src="https://publications.waset.org/10009797.pdf" style="width:100%; height:400px;" frameborder="0"></iframe> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/search?q=Random-effects" title="Random-effects">Random-effects</a>, <a href="https://publications.waset.org/search?q=meta-analysis" title=" meta-analysis"> meta-analysis</a>, <a href="https://publications.waset.org/search?q=Bayesian" title=" Bayesian"> Bayesian</a>, <a href="https://publications.waset.org/search?q=variation." title=" variation."> variation.</a> </p> <p class="card-text"><strong>Digital Object Identifier (DOI):</strong> <a href="https://doi.org/10.5281/zenodo.2021865" target="_blank">doi.org/10.5281/zenodo.2021865</a> </p> <a href="https://publications.waset.org/10009797/bayesian-meta-analysis-to-account-for-heterogeneity-in-studies-relating-life-events-to-disease" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/10009797/apa" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">APA</a> <a href="https://publications.waset.org/10009797/bibtex" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">BibTeX</a> <a href="https://publications.waset.org/10009797/chicago" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Chicago</a> <a href="https://publications.waset.org/10009797/endnote" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">EndNote</a> <a href="https://publications.waset.org/10009797/harvard" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Harvard</a> <a href="https://publications.waset.org/10009797/json" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">JSON</a> <a href="https://publications.waset.org/10009797/mla" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">MLA</a> <a href="https://publications.waset.org/10009797/ris" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">RIS</a> <a href="https://publications.waset.org/10009797/xml" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">XML</a> <a href="https://publications.waset.org/10009797/iso690" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">ISO 690</a> <a href="https://publications.waset.org/10009797.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">659</span> </span> <p class="card-text"><strong>References:</strong></p> <br>[1] C. L. Cooper and R. Payne, Personality and stress: individual differences in the stress process. Chichester, UK: Wiley, (1991). <br>[2] A. Rozanski, J. A. Blumenthal and J. Kaplan, Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy. Circulation; 99, 2192-217 (1999). <br>[3] C. C. Chen, A. S. David, H. Nunnerley, M. Michell, J. L. Dawson, H. Berry, J. Dobbs and T. Fahy, Adverse life events and breast cancer: case-control study. British Medical Journal 311, 1527-30 (1995). <br>[4] S. F. Duijts, M. P. Zeegers and B. V. Borne, The association between stressful life events and breast cancer risk: A meta-analysis. International Journal of Cancer 107, 1023–1029 (2003). <br>[5] F. D. Roberts, P. A. Newcomb, A. Trentham-Dietz, B. E. Storer, Self-Reported Stress and Risk of Breast Cancer. Cancer 77, 1089-1093 (1996). <br>[6] W. H. DuMouchel, Bayesian meta analysis in statistical methodology. Pharmaceutical Sciences, D Berry Ed Marcel Dekker (1990). <br>[7] D. G. Fryback, N. K. Stout and M. A. Rosenberg, An Elementary Introduction to Bayesian Computing Using WinBUGS. International Journal of Technology Assessment in Health Care, 17, 98-113 (2001). <br>[8] D. J. Spiegelhalter, A. Thomas and N. Best, “WinBugs Version 1.4 User Manual”, MRC Biostatistics Unit, software available at http://www.mrcbsu.cam.ac.uk/bugs/ winbugs/contents.shtml (2000). </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">© 2024 World Academy of Science, Engineering and Technology</div> </div> </footer> <a href="javascript:" id="return-to-top"><i class="fas fa-arrow-up"></i></a> <div class="modal" id="modal-template"> <div class="modal-dialog"> <div class="modal-content"> <div class="row m-0 mt-1"> <div class="col-md-12"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> </div> </div> <div class="modal-body"></div> </div> </div> </div> <script src="https://cdn.waset.org/static/plugins/jquery-3.3.1.min.js"></script> <script src="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.waset.org/static/js/site.js?v=150220211556"></script> <script> jQuery(document).ready(function() { /*jQuery.get("https://publications.waset.org/xhr/user-menu", function (response) { jQuery('#mainNavMenu').append(response); });*/ jQuery.get({ url: "https://publications.waset.org/xhr/user-menu", cache: false }).then(function(response){ jQuery('#mainNavMenu').append(response); }); }); </script> </body> </html>

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Bayesian Meta-Analysis to Account for Heterogeneity in Studies Relating Life Events to Disease