CINXE.COM
CD81 - Wikipedia
<!DOCTYPE html> <html class="client-nojs vector-feature-language-in-header-enabled vector-feature-language-in-main-page-header-disabled vector-feature-page-tools-pinned-disabled vector-feature-toc-pinned-clientpref-1 vector-feature-main-menu-pinned-disabled vector-feature-limited-width-clientpref-1 vector-feature-limited-width-content-enabled vector-feature-custom-font-size-clientpref-1 vector-feature-appearance-pinned-clientpref-1 vector-feature-night-mode-enabled skin-theme-clientpref-day vector-sticky-header-enabled vector-toc-available" lang="en" dir="ltr"> <head> <meta charset="UTF-8"> <title>CD81 - Wikipedia</title> <script>(function(){var className="client-js vector-feature-language-in-header-enabled vector-feature-language-in-main-page-header-disabled vector-feature-page-tools-pinned-disabled vector-feature-toc-pinned-clientpref-1 vector-feature-main-menu-pinned-disabled vector-feature-limited-width-clientpref-1 vector-feature-limited-width-content-enabled vector-feature-custom-font-size-clientpref-1 vector-feature-appearance-pinned-clientpref-1 vector-feature-night-mode-enabled skin-theme-clientpref-day vector-sticky-header-enabled vector-toc-available";var cookie=document.cookie.match(/(?:^|; )enwikimwclientpreferences=([^;]+)/);if(cookie){cookie[1].split('%2C').forEach(function(pref){className=className.replace(new RegExp('(^| )'+pref.replace(/-clientpref-\w+$|[^\w-]+/g,'')+'-clientpref-\\w+( |$)'),'$1'+pref+'$2');});}document.documentElement.className=className;}());RLCONF={"wgBreakFrames":false,"wgSeparatorTransformTable":["",""],"wgDigitTransformTable":["",""],"wgDefaultDateFormat":"dmy","wgMonthNames":["","January","February","March","April","May","June","July","August","September","October","November","December"],"wgRequestId":"95f781dc-dac1-46c6-ae89-481c78456cd0","wgCanonicalNamespace":"","wgCanonicalSpecialPageName":false,"wgNamespaceNumber":0,"wgPageName":"CD81","wgTitle":"CD81","wgCurRevisionId":1251266020,"wgRevisionId":1251266020,"wgArticleId":14722590,"wgIsArticle":true,"wgIsRedirect":false,"wgAction":"view","wgUserName":null,"wgUserGroups":["*"],"wgCategories":["Articles with short description","Short description is different from Wikidata","Wikipedia articles incorporating text from the United States National Library of Medicine","Genes on human chromosome 11","Clusters of differentiation"],"wgPageViewLanguage":"en","wgPageContentLanguage":"en","wgPageContentModel":"wikitext","wgRelevantPageName":"CD81","wgRelevantArticleId":14722590,"wgIsProbablyEditable":true,"wgRelevantPageIsProbablyEditable":true,"wgRestrictionEdit":[],"wgRestrictionMove":[],"wgNoticeProject":"wikipedia","wgCiteReferencePreviewsActive":false,"wgFlaggedRevsParams":{"tags":{"status":{"levels":1}}},"wgMediaViewerOnClick":true,"wgMediaViewerEnabledByDefault":true,"wgPopupsFlags":0,"wgVisualEditor":{"pageLanguageCode":"en","pageLanguageDir":"ltr","pageVariantFallbacks":"en"},"wgMFDisplayWikibaseDescriptions":{"search":true,"watchlist":true,"tagline":false,"nearby":true},"wgWMESchemaEditAttemptStepOversample":false,"wgWMEPageLength":20000,"wgEditSubmitButtonLabelPublish":true,"wgULSPosition":"interlanguage","wgULSisCompactLinksEnabled":false,"wgVector2022LanguageInHeader":true,"wgULSisLanguageSelectorEmpty":false,"wgWikibaseItemId":"Q21131199","wgCheckUserClientHintsHeadersJsApi":["brands","architecture","bitness","fullVersionList","mobile","model","platform","platformVersion"],"GEHomepageSuggestedEditsEnableTopics":true,"wgGETopicsMatchModeEnabled":false,"wgGEStructuredTaskRejectionReasonTextInputEnabled":false,"wgGELevelingUpEnabledForUser":false}; RLSTATE={"ext.globalCssJs.user.styles":"ready","site.styles":"ready","user.styles":"ready","ext.globalCssJs.user":"ready","user":"ready","user.options":"loading","ext.cite.styles":"ready","mediawiki.page.gallery.styles":"ready","skins.vector.search.codex.styles":"ready","skins.vector.styles":"ready","skins.vector.icons":"ready","jquery.makeCollapsible.styles":"ready","ext.wikimediamessages.styles":"ready","ext.visualEditor.desktopArticleTarget.noscript":"ready","ext.uls.interlanguage":"ready","wikibase.client.init":"ready"};RLPAGEMODULES=["ext.cite.ux-enhancements","site","mediawiki.page.ready","jquery.makeCollapsible","mediawiki.toc","skins.vector.js","ext.centralNotice.geoIP","ext.centralNotice.startUp","ext.gadget.ReferenceTooltips","ext.gadget.switcher","ext.urlShortener.toolbar","ext.centralauth.centralautologin","mmv.bootstrap","ext.popups","ext.visualEditor.desktopArticleTarget.init","ext.visualEditor.targetLoader","ext.echo.centralauth","ext.eventLogging","ext.wikimediaEvents","ext.navigationTiming","ext.uls.interface","ext.cx.eventlogging.campaigns","ext.cx.uls.quick.actions","wikibase.client.vector-2022","ext.checkUser.clientHints","ext.growthExperiments.SuggestedEditSession"];</script> <script>(RLQ=window.RLQ||[]).push(function(){mw.loader.impl(function(){return["user.options@12s5i",function($,jQuery,require,module){mw.user.tokens.set({"patrolToken":"+\\","watchToken":"+\\","csrfToken":"+\\"}); }];});});</script> <link rel="stylesheet" href="/w/load.php?lang=en&modules=ext.cite.styles%7Cext.uls.interlanguage%7Cext.visualEditor.desktopArticleTarget.noscript%7Cext.wikimediamessages.styles%7Cjquery.makeCollapsible.styles%7Cmediawiki.page.gallery.styles%7Cskins.vector.icons%2Cstyles%7Cskins.vector.search.codex.styles%7Cwikibase.client.init&only=styles&skin=vector-2022"> <script async="" src="/w/load.php?lang=en&modules=startup&only=scripts&raw=1&skin=vector-2022"></script> <meta name="ResourceLoaderDynamicStyles" content=""> <link rel="stylesheet" href="/w/load.php?lang=en&modules=site.styles&only=styles&skin=vector-2022"> <meta name="generator" content="MediaWiki 1.44.0-wmf.19"> <meta name="referrer" content="origin"> <meta name="referrer" content="origin-when-cross-origin"> <meta name="robots" content="max-image-preview:standard"> <meta name="format-detection" content="telephone=no"> <meta property="og:image" content="https://upload.wikimedia.org/wikipedia/commons/2/26/Protein_CD81_PDB_1g8q.png"> <meta property="og:image:width" content="1200"> <meta property="og:image:height" content="771"> <meta property="og:image" content="https://upload.wikimedia.org/wikipedia/commons/thumb/2/26/Protein_CD81_PDB_1g8q.png/800px-Protein_CD81_PDB_1g8q.png"> <meta property="og:image:width" content="800"> <meta property="og:image:height" content="514"> <meta property="og:image" content="https://upload.wikimedia.org/wikipedia/commons/thumb/2/26/Protein_CD81_PDB_1g8q.png/640px-Protein_CD81_PDB_1g8q.png"> <meta property="og:image:width" content="640"> <meta property="og:image:height" content="411"> <meta name="viewport" content="width=1120"> <meta property="og:title" content="CD81 - Wikipedia"> <meta property="og:type" content="website"> <link rel="preconnect" href="//upload.wikimedia.org"> <link rel="alternate" media="only screen and (max-width: 640px)" href="//en.m.wikipedia.org/wiki/CD81"> <link rel="alternate" type="application/x-wiki" title="Edit this page" href="/w/index.php?title=CD81&action=edit"> <link rel="apple-touch-icon" href="/static/apple-touch/wikipedia.png"> <link rel="icon" href="/static/favicon/wikipedia.ico"> <link rel="search" type="application/opensearchdescription+xml" href="/w/rest.php/v1/search" title="Wikipedia (en)"> <link rel="EditURI" type="application/rsd+xml" href="//en.wikipedia.org/w/api.php?action=rsd"> <link rel="canonical" href="https://en.wikipedia.org/wiki/CD81"> <link rel="license" href="https://creativecommons.org/licenses/by-sa/4.0/deed.en"> <link rel="alternate" type="application/atom+xml" title="Wikipedia Atom feed" href="/w/index.php?title=Special:RecentChanges&feed=atom"> <link rel="dns-prefetch" href="//meta.wikimedia.org" /> <link rel="dns-prefetch" href="login.wikimedia.org"> </head> <body class="skin--responsive skin-vector skin-vector-search-vue mediawiki ltr sitedir-ltr mw-hide-empty-elt ns-0 ns-subject mw-editable page-CD81 rootpage-CD81 skin-vector-2022 action-view"><a class="mw-jump-link" href="#bodyContent">Jump to content</a> <div class="vector-header-container"> <header class="vector-header mw-header"> <div class="vector-header-start"> <nav class="vector-main-menu-landmark" aria-label="Site"> <div id="vector-main-menu-dropdown" class="vector-dropdown vector-main-menu-dropdown vector-button-flush-left vector-button-flush-right" title="Main menu" > <input type="checkbox" id="vector-main-menu-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-main-menu-dropdown" class="vector-dropdown-checkbox " aria-label="Main menu" > <label id="vector-main-menu-dropdown-label" for="vector-main-menu-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-menu mw-ui-icon-wikimedia-menu"></span> <span class="vector-dropdown-label-text">Main menu</span> </label> <div class="vector-dropdown-content"> <div id="vector-main-menu-unpinned-container" class="vector-unpinned-container"> <div id="vector-main-menu" class="vector-main-menu vector-pinnable-element"> <div class="vector-pinnable-header vector-main-menu-pinnable-header vector-pinnable-header-unpinned" data-feature-name="main-menu-pinned" data-pinnable-element-id="vector-main-menu" data-pinned-container-id="vector-main-menu-pinned-container" data-unpinned-container-id="vector-main-menu-unpinned-container" > <div class="vector-pinnable-header-label">Main menu</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-main-menu.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-main-menu.unpin">hide</button> </div> <div id="p-navigation" class="vector-menu mw-portlet mw-portlet-navigation" > <div class="vector-menu-heading"> Navigation </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="n-mainpage-description" class="mw-list-item"><a href="/wiki/Main_Page" title="Visit the main page [z]" accesskey="z"><span>Main page</span></a></li><li id="n-contents" class="mw-list-item"><a href="/wiki/Wikipedia:Contents" title="Guides to browsing Wikipedia"><span>Contents</span></a></li><li id="n-currentevents" class="mw-list-item"><a href="/wiki/Portal:Current_events" title="Articles related to current events"><span>Current events</span></a></li><li id="n-randompage" class="mw-list-item"><a href="/wiki/Special:Random" title="Visit a randomly selected article [x]" accesskey="x"><span>Random article</span></a></li><li id="n-aboutsite" class="mw-list-item"><a href="/wiki/Wikipedia:About" title="Learn about Wikipedia and how it works"><span>About Wikipedia</span></a></li><li id="n-contactpage" class="mw-list-item"><a href="//en.wikipedia.org/wiki/Wikipedia:Contact_us" title="How to contact Wikipedia"><span>Contact us</span></a></li> </ul> </div> </div> <div id="p-interaction" class="vector-menu mw-portlet mw-portlet-interaction" > <div class="vector-menu-heading"> Contribute </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="n-help" class="mw-list-item"><a href="/wiki/Help:Contents" title="Guidance on how to use and edit Wikipedia"><span>Help</span></a></li><li id="n-introduction" class="mw-list-item"><a href="/wiki/Help:Introduction" title="Learn how to edit Wikipedia"><span>Learn to edit</span></a></li><li id="n-portal" class="mw-list-item"><a href="/wiki/Wikipedia:Community_portal" title="The hub for editors"><span>Community portal</span></a></li><li id="n-recentchanges" class="mw-list-item"><a href="/wiki/Special:RecentChanges" title="A list of recent changes to Wikipedia [r]" accesskey="r"><span>Recent changes</span></a></li><li id="n-upload" class="mw-list-item"><a href="/wiki/Wikipedia:File_upload_wizard" title="Add images or other media for use on Wikipedia"><span>Upload file</span></a></li><li id="n-specialpages" class="mw-list-item"><a href="/wiki/Special:SpecialPages"><span>Special pages</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> <a href="/wiki/Main_Page" class="mw-logo"> <img class="mw-logo-icon" src="/static/images/icons/wikipedia.png" alt="" aria-hidden="true" height="50" width="50"> <span class="mw-logo-container skin-invert"> <img class="mw-logo-wordmark" alt="Wikipedia" src="/static/images/mobile/copyright/wikipedia-wordmark-en.svg" style="width: 7.5em; height: 1.125em;"> <img class="mw-logo-tagline" alt="The Free Encyclopedia" src="/static/images/mobile/copyright/wikipedia-tagline-en.svg" width="117" height="13" style="width: 7.3125em; height: 0.8125em;"> </span> </a> </div> <div class="vector-header-end"> <div id="p-search" role="search" class="vector-search-box-vue vector-search-box-collapses vector-search-box-show-thumbnail vector-search-box-auto-expand-width vector-search-box"> <a href="/wiki/Special:Search" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only search-toggle" title="Search Wikipedia [f]" accesskey="f"><span class="vector-icon mw-ui-icon-search mw-ui-icon-wikimedia-search"></span> <span>Search</span> </a> <div class="vector-typeahead-search-container"> <div class="cdx-typeahead-search cdx-typeahead-search--show-thumbnail cdx-typeahead-search--auto-expand-width"> <form action="/w/index.php" id="searchform" class="cdx-search-input cdx-search-input--has-end-button"> <div id="simpleSearch" class="cdx-search-input__input-wrapper" data-search-loc="header-moved"> <div class="cdx-text-input cdx-text-input--has-start-icon"> <input class="cdx-text-input__input" type="search" name="search" placeholder="Search Wikipedia" aria-label="Search Wikipedia" autocapitalize="sentences" title="Search Wikipedia [f]" accesskey="f" id="searchInput" > <span class="cdx-text-input__icon cdx-text-input__start-icon"></span> </div> <input type="hidden" name="title" value="Special:Search"> </div> <button class="cdx-button cdx-search-input__end-button">Search</button> </form> </div> </div> </div> <nav class="vector-user-links vector-user-links-wide" aria-label="Personal tools"> <div class="vector-user-links-main"> <div id="p-vector-user-menu-preferences" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-userpage" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <nav class="vector-appearance-landmark" aria-label="Appearance"> <div id="vector-appearance-dropdown" class="vector-dropdown " title="Change the appearance of the page's font size, width, and color" > <input type="checkbox" id="vector-appearance-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-appearance-dropdown" class="vector-dropdown-checkbox " aria-label="Appearance" > <label id="vector-appearance-dropdown-label" for="vector-appearance-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-appearance mw-ui-icon-wikimedia-appearance"></span> <span class="vector-dropdown-label-text">Appearance</span> </label> <div class="vector-dropdown-content"> <div id="vector-appearance-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <div id="p-vector-user-menu-notifications" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-overflow" class="vector-menu mw-portlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="https://donate.wikimedia.org/?wmf_source=donate&wmf_medium=sidebar&wmf_campaign=en.wikipedia.org&uselang=en" class=""><span>Donate</span></a> </li> <li id="pt-createaccount-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Special:CreateAccount&returnto=CD81" title="You are encouraged to create an account and log in; however, it is not mandatory" class=""><span>Create account</span></a> </li> <li id="pt-login-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Special:UserLogin&returnto=CD81" title="You're encouraged to log in; however, it's not mandatory. [o]" accesskey="o" class=""><span>Log in</span></a> </li> </ul> </div> </div> </div> <div id="vector-user-links-dropdown" class="vector-dropdown vector-user-menu vector-button-flush-right vector-user-menu-logged-out" title="Log in and more options" > <input type="checkbox" id="vector-user-links-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-user-links-dropdown" class="vector-dropdown-checkbox " aria-label="Personal tools" > <label id="vector-user-links-dropdown-label" for="vector-user-links-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-ellipsis mw-ui-icon-wikimedia-ellipsis"></span> <span class="vector-dropdown-label-text">Personal tools</span> </label> <div class="vector-dropdown-content"> <div id="p-personal" class="vector-menu mw-portlet mw-portlet-personal user-links-collapsible-item" title="User menu" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport" class="user-links-collapsible-item mw-list-item"><a href="https://donate.wikimedia.org/?wmf_source=donate&wmf_medium=sidebar&wmf_campaign=en.wikipedia.org&uselang=en"><span>Donate</span></a></li><li id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:CreateAccount&returnto=CD81" title="You are encouraged to create an account and log in; however, it is not mandatory"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>Create account</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:UserLogin&returnto=CD81" title="You're encouraged to log in; however, it's not mandatory. [o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>Log in</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> Pages for logged out editors <a href="/wiki/Help:Introduction" aria-label="Learn more about editing"><span>learn more</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/Special:MyContributions" title="A list of edits made from this IP address [y]" accesskey="y"><span>Contributions</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/Special:MyTalk" title="Discussion about edits from this IP address [n]" accesskey="n"><span>Talk</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"><!-- CentralNotice --></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="Site"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="Contents" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">Contents</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">hide</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">(Top)</div> </a> </li> <li id="toc-Gene" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Gene"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Gene</span> </div> </a> <ul id="toc-Gene-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Function" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Function"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Function</span> </div> </a> <ul id="toc-Function-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Clinical_significance" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Clinical_significance"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Clinical significance</span> </div> </a> <ul id="toc-Clinical_significance-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Interactions" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Interactions"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Interactions</span> </div> </a> <button aria-controls="toc-Interactions-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Interactions subsection</span> </button> <ul id="toc-Interactions-sublist" class="vector-toc-list"> <li id="toc-Ligands" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Ligands"> <div class="vector-toc-text"> <span class="vector-toc-numb">4.1</span> <span>Ligands</span> </div> </a> <ul id="toc-Ligands-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-See_also" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#See_also"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>See also</span> </div> </a> <ul id="toc-See_also-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>References</span> </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Further_reading" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Further_reading"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>Further reading</span> </div> </a> <ul id="toc-Further_reading-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-External_links" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#External_links"> <div class="vector-toc-text"> <span class="vector-toc-numb">8</span> <span>External links</span> </div> </a> <ul id="toc-External_links-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contents" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" title="Table of Contents" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Toggle the table of contents" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Toggle the table of contents</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">CD81</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. Available in 9 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-9" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">9 languages</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/CD81" title="CD81 – Bosnian" lang="bs" hreflang="bs" data-title="CD81" data-language-autonym="Bosanski" data-language-local-name="Bosnian" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/CD81" title="CD81 – Welsh" lang="cy" hreflang="cy" data-title="CD81" data-language-autonym="Cymraeg" data-language-local-name="Welsh" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/CD81" title="CD81 – German" lang="de" hreflang="de" data-title="CD81" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/CD81" title="CD81 – Persian" lang="fa" hreflang="fa" data-title="CD81" data-language-autonym="فارسی" data-language-local-name="Persian" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/CD81" title="CD81 – Indonesian" lang="id" hreflang="id" data-title="CD81" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonesian" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/CD81" title="CD81 – Russian" lang="ru" hreflang="ru" data-title="CD81" data-language-autonym="Русский" data-language-local-name="Russian" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-tt mw-list-item"><a href="https://tt.wikipedia.org/wiki/CD81" title="CD81 – Tatar" lang="tt" hreflang="tt" data-title="CD81" data-language-autonym="Татарча / tatarça" data-language-local-name="Tatar" class="interlanguage-link-target"><span>Татарча / tatarça</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/CD81" title="CD81 – Turkish" lang="tr" hreflang="tr" data-title="CD81" data-language-autonym="Türkçe" data-language-local-name="Turkish" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/CD81" title="CD81 – Ukrainian" lang="uk" hreflang="uk" data-title="CD81" data-language-autonym="Українська" data-language-local-name="Ukrainian" class="interlanguage-link-target"><span>Українська</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q21131199#sitelinks-wikipedia" title="Edit interlanguage links" class="wbc-editpage">Edit links</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Namespaces"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/CD81" title="View the content page [c]" accesskey="c"><span>Article</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/Talk:CD81" rel="discussion" title="Discuss improvements to the content page [t]" accesskey="t"><span>Talk</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="Change language variant" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">English</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="Views"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/CD81"><span>Read</span></a></li><li id="ca-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=CD81&action=edit" title="Edit this page [e]" accesskey="e"><span>Edit</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=CD81&action=history" title="Past revisions of this page [h]" accesskey="h"><span>View history</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Page tools"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="Tools" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Tools</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Tools</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">hide</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="More options" > <div class="vector-menu-heading"> Actions </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/CD81"><span>Read</span></a></li><li id="ca-more-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=CD81&action=edit" title="Edit this page [e]" accesskey="e"><span>Edit</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=CD81&action=history"><span>View history</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> General </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/Special:WhatLinksHere/CD81" title="List of all English Wikipedia pages containing links to this page [j]" accesskey="j"><span>What links here</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/Special:RecentChangesLinked/CD81" rel="nofollow" title="Recent changes in pages linked from this page [k]" accesskey="k"><span>Related changes</span></a></li><li id="t-upload" class="mw-list-item"><a href="//en.wikipedia.org/wiki/Wikipedia:File_Upload_Wizard" title="Upload files [u]" accesskey="u"><span>Upload file</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=CD81&oldid=1251266020" title="Permanent link to this revision of this page"><span>Permanent link</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=CD81&action=info" title="More information about this page"><span>Page information</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=Special:CiteThisPage&page=CD81&id=1251266020&wpFormIdentifier=titleform" title="Information on how to cite this page"><span>Cite this page</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=Special:UrlShortener&url=https%3A%2F%2Fen.wikipedia.org%2Fwiki%2FCD81"><span>Get shortened URL</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=Special:QrCode&url=https%3A%2F%2Fen.wikipedia.org%2Fwiki%2FCD81"><span>Download QR code</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" > <div class="vector-menu-heading"> Print/export </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=Special:DownloadAsPdf&page=CD81&action=show-download-screen" title="Download this page as a PDF file"><span>Download as PDF</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=CD81&printable=yes" title="Printable version of this page [p]" accesskey="p"><span>Printable version</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> In other projects </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="wb-otherproject-link wb-otherproject-commons mw-list-item"><a href="https://commons.wikimedia.org/wiki/Category:CD81_antigens" hreflang="en"><span>Wikimedia Commons</span></a></li><li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q21131199" title="Structured data on this page hosted by Wikidata [g]" accesskey="g"><span>Wikidata item</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Page tools"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Appearance"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Appearance</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">hide</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">From Wikipedia, the free encyclopedia</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Mammalian protein found in humans</div> <table class="infobox" style="width:26.4em"><tbody><tr><th colspan="4" style="text-align:center;font-size:125%;font-weight:bold">CD81</th></tr><tr><td colspan="4" style="text-align:center"><span typeof="mw:File"><a href="/wiki/File:Protein_CD81_PDB_1g8q.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/2/26/Protein_CD81_PDB_1g8q.png/250px-Protein_CD81_PDB_1g8q.png" decoding="async" width="250" height="161" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/26/Protein_CD81_PDB_1g8q.png/375px-Protein_CD81_PDB_1g8q.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/26/Protein_CD81_PDB_1g8q.png/500px-Protein_CD81_PDB_1g8q.png 2x" data-file-width="945" data-file-height="607" /></a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit">Available structures</th></tr><tr><th rowspan="2" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit;width:43px"><a href="/wiki/Protein_Data_Bank" title="Protein Data Bank">PDB</a></th><td colspan="2" style="background-color:light-dark(#eee, #27292d) !important;color:inherit">Ortholog search: <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/pdbe/searchResults.html?display=both&term=P35762%20or%20P60033%20or%20E9PPF5">PDBe</a> <a rel="nofollow" class="external text" href="https://www.rcsb.org/search?q=rcsb_polymer_entity_container_identifiers.reference_sequence_identifiers.database_name:UniProt%20AND%20rcsb_polymer_entity_container_identifiers.reference_sequence_identifiers.database_accession:P35762,P60033,E9PPF5">RCSB</a> </span></td></tr><tr><td><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr style="text-align:center"><th colspan="2" style="background-color:light-dark(#ddd, #404244) !important;color:inherit">List of PDB id codes</th></tr><tr><td colspan="2" style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1G8Q">1G8Q</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1IV5">1IV5</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3X0E">3X0E</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/5DFW">5DFW</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/5DFV">5DFV</a></span></p></td></tr></tbody></table></td></tr></tbody></table></td></tr><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit">Identifiers</th></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><span class="plainlinks"><a href="/wiki/Gene_nomenclature" title="Gene nomenclature">Aliases</a></span></th><td colspan="3" style="background:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/1701">CD81</a></span>, CVID6, S5.7, TAPA1, TSPAN28, CD81 molecule</td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">External IDs</th><td colspan="3" style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks"><a href="/wiki/Mendelian_Inheritance_in_Man" class="mw-redirect" title="Mendelian Inheritance in Man">OMIM</a>: <a rel="nofollow" class="external text" href="https://omim.org/entry/186845">186845</a>; <a href="/wiki/Mouse_Genome_Informatics" title="Mouse Genome Informatics">MGI</a>: <a rel="nofollow" class="external text" href="http://www.informatics.jax.org/marker/MGI:1096398">1096398</a>; <a href="/wiki/HomoloGene" title="HomoloGene">HomoloGene</a>: <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=20915">20915</a>; <a href="/wiki/GeneCards" title="GeneCards">GeneCards</a>: <a rel="nofollow" class="external text" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=CD81">CD81</a>; <a href="/wiki/Orthologous_MAtrix" title="Orthologous MAtrix">OMA</a>:<a rel="nofollow" class="external text" href="https://omabrowser.org/oma/vps/ENSG00000110651">CD81 - orthologs</a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit">Gene location (<a href="/wiki/Human_genome" title="Human genome">Human</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><span typeof="mw:File"><a href="/wiki/File:Ideogram_human_chromosome_11.svg" class="mw-file-description" title="Chromosome 11 (human)"><img alt="Chromosome 11 (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_human_chromosome_11.svg/300px-Ideogram_human_chromosome_11.svg.png" decoding="async" width="300" height="120" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_human_chromosome_11.svg/450px-Ideogram_human_chromosome_11.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_human_chromosome_11.svg/600px-Ideogram_human_chromosome_11.svg.png 2x" data-file-width="474" data-file-height="189" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/Chromosome" title="Chromosome">Chr.</a></th><td colspan="3" width="85%" style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks"><a href="/wiki/Chromosome_11_(human)" class="mw-redirect" title="Chromosome 11 (human)">Chromosome 11 (human)</a><sup id="cite_ref-refGRCh38Ensembl_1-0" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/File:Human_chromosome_11_ideogram.svg" class="mw-file-description" title="Chromosome 11 (human)"><img alt="Chromosome 11 (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/43/Human_chromosome_11_ideogram.svg/300px-Human_chromosome_11_ideogram.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/43/Human_chromosome_11_ideogram.svg/450px-Human_chromosome_11_ideogram.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/43/Human_chromosome_11_ideogram.svg/600px-Human_chromosome_11_ideogram.svg.png 2x" data-file-width="1125" data-file-height="216" /></a></span><div style="position: absolute; left: -0.20308791770365px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomic location for CD81"><img alt="Genomic location for CD81" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 5.8px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:Red_rectangle_2x18.png" class="mw-file-description" title="Genomic location for CD81"><img alt="Genomic location for CD81" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Band</a></th><td rowspan="2" width="35%" style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">11p15.5</span></td><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">Start</th><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">2,376,177 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-1" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">End</th><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">2,397,397 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-2" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit">Gene location (<a href="/wiki/Laboratory_mouse" title="Laboratory mouse">Mouse</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><span typeof="mw:File"><a href="/wiki/File:Ideogram_house_mouse_chromosome_7.svg" class="mw-file-description" title="Chromosome 7 (mouse)"><img alt="Chromosome 7 (mouse)" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Ideogram_house_mouse_chromosome_7.svg/260px-Ideogram_house_mouse_chromosome_7.svg.png" decoding="async" width="260" height="111" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Ideogram_house_mouse_chromosome_7.svg/390px-Ideogram_house_mouse_chromosome_7.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Ideogram_house_mouse_chromosome_7.svg/520px-Ideogram_house_mouse_chromosome_7.svg.png 2x" data-file-width="470" data-file-height="200" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/Chromosome" title="Chromosome">Chr.</a></th><td colspan="3" width="85%" style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">Chromosome 7 (mouse)<sup id="cite_ref-refGRCm38Ensembl_2-0" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/File:Ideogram_of_house_mouse_chromosome_7.svg" class="mw-file-description" title="Chromosome 7 (mouse)"><img alt="Chromosome 7 (mouse)" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/2c/Ideogram_of_house_mouse_chromosome_7.svg/300px-Ideogram_of_house_mouse_chromosome_7.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/2c/Ideogram_of_house_mouse_chromosome_7.svg/450px-Ideogram_of_house_mouse_chromosome_7.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/2c/Ideogram_of_house_mouse_chromosome_7.svg/600px-Ideogram_of_house_mouse_chromosome_7.svg.png 2x" data-file-width="1200" data-file-height="231" /></a></span><div style="position: absolute; left: 283.01524343888px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomic location for CD81"><img alt="Genomic location for CD81" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 289px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:Red_rectangle_2x18.png" class="mw-file-description" title="Genomic location for CD81"><img alt="Genomic location for CD81" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Band</a></th><td rowspan="2" width="35%" style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">7 F5|7 88.1 cM</span></td><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">Start</th><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">142,606,476 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCm38Ensembl_2-1" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">End</th><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">142,621,671 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCm38Ensembl_2-2" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit"><a href="/wiki/Gene_expression" title="Gene expression">RNA expression</a> pattern</th></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a rel="nofollow" class="external text" href="https://www.bgee.org/">Bgee</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th><b><a href="/wiki/Human_genome" title="Human genome">Human</a></b></th><th><b><a href="/wiki/Laboratory_mouse" title="Laboratory mouse">Mouse</a> (ortholog)</b></th></tr><tr><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="1"><span class="plainlinks" style="margin:-3px"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSG00000110651">Top expressed in</a></span></td></tr><tr><td colspan="1"><div class="plainlinks" style="margin:-12px 0px -10px 0px"><ul style="line-height:15%;margin:9px"><li style="line-height: 137%;">stromal cell of endometrium</li><br /><li style="line-height: 137%;">seminal vesicula</li><br /><li style="line-height: 137%;">body of uterus</li><br /><li style="line-height: 137%;">right coronary artery</li><br /><li style="line-height: 137%;">canal of the cervix</li><br /><li style="line-height: 137%;">right uterine tube</li><br /><li style="line-height: 137%;">Descending thoracic aorta</li><br /><li style="line-height: 137%;">left uterine tube</li><br /><li style="line-height: 137%;">ascending aorta</li><br /><li style="line-height: 137%;">apex of heart</li></ul></div></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="1"><span class="plainlinks" style="margin:-3px"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSMUSG00000037706">Top expressed in</a></span></td></tr><tr><td colspan="1"><div class="plainlinks" style="margin:-12px 0px -10px 0px"><ul style="line-height:15%;margin:9px"><li style="line-height: 137%;">aortic valve</li><br /><li style="line-height: 137%;">ascending aorta</li><br /><li style="line-height: 137%;">anterior horn of spinal cord</li><br /><li style="line-height: 137%;">Epithelium of choroid plexus</li><br /><li style="line-height: 137%;">efferent ductule</li><br /><li style="line-height: 137%;">dentate gyrus of hippocampal formation granule cell</li><br /><li style="line-height: 137%;">molar</li><br /><li style="line-height: 137%;">optic nerve</li><br /><li style="line-height: 137%;">external carotid artery</li><br /><li style="line-height: 137%;">choroid plexus of fourth ventricle</li></ul></div></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSG00000110651">More reference expression data</a></span></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a rel="nofollow" class="external text" href="http://biogps.org/">BioGPS</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><span typeof="mw:File"><a href="/wiki/File:PBB_GE_CD81_200675_at_fs.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ef/PBB_GE_CD81_200675_at_fs.png/250px-PBB_GE_CD81_200675_at_fs.png" decoding="async" width="250" height="181" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ef/PBB_GE_CD81_200675_at_fs.png/375px-PBB_GE_CD81_200675_at_fs.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/ef/PBB_GE_CD81_200675_at_fs.png/500px-PBB_GE_CD81_200675_at_fs.png 2x" data-file-width="732" data-file-height="530" /></a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://biogps.org/gene/975/">More reference expression data</a></span></td></tr></tbody></table></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit"><a href="/wiki/Gene_ontology" class="mw-redirect" title="Gene ontology">Gene ontology</a></th></tr><tr><td style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit;font-weight:bold">Molecular function</td><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005515">protein binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0023026">MHC class II protein complex binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1990459">transferrin receptor binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0001618">virus receptor activity</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005178">integrin binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0015485">cholesterol binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0008289">lipid binding</a></li></ul> </div></td></tr><tr><td style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit;font-weight:bold">Cellular component</td><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016021">integral component of membrane</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0031982">vesicle</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016020">membrane</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005925">focal adhesion</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005887">integral component of plasma membrane</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0001772">immunological synapse</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0070062">extracellular exosome</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005886">plasma membrane</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016323">basolateral plasma membrane</a></li></ul> </div></td></tr><tr><td style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit;font-weight:bold">Biological process</td><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0043128">positive regulation of 1-phosphatidylinositol 4-kinase activity</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0008104">protein localization</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0031647">regulation of protein stability</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0031623">receptor internalization</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0071404">cellular response to low-density lipoprotein particle stimulus</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:2000145">regulation of cell motility</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0046813">receptor-mediated virion attachment to host cell</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0061462">protein localization to lysosome</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007166">cell surface receptor signaling pathway</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0030890">positive regulation of B cell proliferation</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0008284">positive regulation of cell population proliferation</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0050776">regulation of immune response</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0050731">positive regulation of peptidyl-tyrosine phosphorylation</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0046718">viral entry into host cell</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1904352">positive regulation of protein catabolic process in the vacuole</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0008283">cell population proliferation</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016032">viral process</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0045944">positive regulation of transcription by RNA polymerase II</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0030449">regulation of complement activation</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0002455">humoral immune response mediated by circulating immunoglobulin</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0072659">protein localization to plasma membrane</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0002250">adaptive immune response</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0002376">immune system process</a></li></ul> </div></td></tr><tr><td colspan="4" style="background-color:light-dark(#eee, #27292d) !important;color:inherit;text-align:center">Sources:<a rel="nofollow" class="external text" href="http://amigo.geneontology.org/">Amigo</a> / <a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/QuickGO/">QuickGO</a></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table class="collapsible" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit"><a href="/wiki/Orthologs" class="mw-redirect" title="Orthologs">Orthologs</a></th></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">Species</th><td><b>Human</b></td><td><b>Mouse</b></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/Entrez" title="Entrez">Entrez</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=975&rn=1">975</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=12520&rn=1">12520</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/Ensembl" class="mw-redirect" title="Ensembl">Ensembl</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000110651;db=core">ENSG00000110651</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Mus_musculus/geneview?gene=ENSMUSG00000037706;db=core">ENSMUSG00000037706</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/UniProt" title="UniProt">UniProt</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/P60033">P60033</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/P35762">P35762</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">RefSeq (mRNA)</th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001297649">NM_001297649</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_004356">NM_004356</a></span></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_133655">NM_133655</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">RefSeq (protein)</th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001284578">NP_001284578</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_004347">NP_004347</a></span></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_598416">NP_598416</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">Location (UCSC)</th><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Human&db=hg38&position=chr11:2376177-2397397">Chr 11: 2.38 – 2.4 Mb</a></span></td><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Mouse&db=mm0&position=chr7:142606476-142621671">Chr 7: 142.61 – 142.62 Mb</a></span></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/PubMed" title="PubMed">PubMed</a> search</th><td><span class="plainlinks"><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></span></td><td><span class="plainlinks"><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><a href="/wiki/Wikidata" title="Wikidata">Wikidata</a></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="2" style="background-color:light-dark(#eee, #27292d) !important;color:inherit;text-align:center"><a href="https://www.wikidata.org/wiki/Q17859703" class="extiw" title="d:Q17859703">View/Edit Human</a></td><td colspan="2" style="background-color:light-dark(#eee, #27292d) !important;color:inherit;text-align:center"><a href="https://www.wikidata.org/wiki/Q18248227" class="extiw" title="d:Q18248227">View/Edit Mouse</a></td></tr></tbody></table></td></tr></tbody></table> <p><b>CD81 molecule</b>, also known as <b>CD81</b> (<b>C</b>luster of <b>D</b>ifferentiation <b>81</b>), is a <a href="/wiki/Protein" title="Protein">protein</a> which in humans is encoded by the <i>CD81</i> <a href="/wiki/Gene" title="Gene">gene</a>.<sup id="cite_ref-entrez_5-0" class="reference"><a href="#cite_note-entrez-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid1650385_6-0" class="reference"><a href="#cite_note-pmid1650385-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> It is also known as 26 kDa cell surface protein, TAPA-1 (<b>T</b>arget of the <b>A</b>nti<b>p</b>roliferative <b>A</b>ntibody 1), and Tetraspanin-28 (Tspan-28). </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Gene">Gene</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CD81&action=edit&section=1" title="Edit section: Gene"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The gene is located on the plus strand of the short arm of <a href="/wiki/Chromosome_11" title="Chromosome 11">chromosome 11</a> (11p15.5). It is 20,103 bases in length and encodes a protein of 236 <a href="/wiki/Amino_acid" title="Amino acid">amino acids</a> (predicted molecular weight 25.809 <a href="/wiki/Dalton_(unit)" title="Dalton (unit)">kDa</a>).<sup id="cite_ref-pmid1650385_6-1" class="reference"><a href="#cite_note-pmid1650385-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>The protein does not appear to be post translationally modified and has four transmembrane domains. Both the <a href="/wiki/N-terminus" title="N-terminus">N-terminus</a> and <a href="/wiki/C-terminus" title="C-terminus">C-terminus</a> lie on the intracellular side of the membrane. </p><p>The gene is expressed in <a href="/wiki/Hemopoietic" class="mw-redirect" title="Hemopoietic">hemopoietic</a>, <a href="/wiki/Endothelial" class="mw-redirect" title="Endothelial">endothelial</a>, and <a href="/wiki/Epithelial" class="mw-redirect" title="Epithelial">epithelial</a> cells. It is absent from <a href="/wiki/Erythrocyte" class="mw-redirect" title="Erythrocyte">erythrocytes</a>, <a href="/wiki/Platelet" title="Platelet">platelets</a>, and <a href="/wiki/Neutrophil" title="Neutrophil">neutrophils</a>. </p> <div class="mw-heading mw-heading2"><h2 id="Function">Function</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CD81&action=edit&section=2" title="Edit section: Function"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the <a href="/wiki/Tetraspanin" title="Tetraspanin">tetraspanin</a> family. Most of these members are cell-surface proteins that are characterized by the presence of four <a href="/wiki/Hydrophobic" class="mw-redirect" title="Hydrophobic">hydrophobic</a> <a href="/wiki/Protein_domain" title="Protein domain">domains</a>. The proteins mediate <a href="/wiki/Signal_transduction" title="Signal transduction">signal transduction</a> events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface <a href="/wiki/Glycoprotein" title="Glycoprotein">glycoprotein</a> that is known to complex with <i>integrin</i>s. This protein appears to promote muscle cell fusion and support <a href="/wiki/Myotube" class="mw-redirect" title="Myotube">myotube</a> maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies.<sup id="cite_ref-entrez_5-1" class="reference"><a href="#cite_note-entrez-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p><p>The tetraspanin family includes <a href="/wiki/CD9" title="CD9">CD9</a>, <a href="/wiki/CD37" title="CD37">CD37</a>, <a href="/wiki/CD53" title="CD53">CD53</a>, <a href="/wiki/CD63" title="CD63">CD63</a>, CD81 (this protein), <a href="/wiki/CD82" class="mw-redirect" title="CD82">CD82</a> and <a href="/wiki/CD151" title="CD151">CD151</a>. </p><p>CD81 interacts directly with immunoglobulin superfamily member 8 (<a href="/wiki/IGSF8" title="IGSF8">IGSF8</a>,<sup id="cite_ref-pmid11673522_7-0" class="reference"><a href="#cite_note-pmid11673522-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> <a href="/wiki/CD316" class="mw-redirect" title="CD316">CD316</a>) and <a href="/wiki/CD36" title="CD36">CD36</a>. It forms a signal transduction complex with <a href="/wiki/CD19" title="CD19">CD19</a>, <a href="/wiki/CD21" class="mw-redirect" title="CD21">CD21</a> and Leu-13 (<a href="/wiki/IFITM1" title="IFITM1">CD225</a>) on the surface of the <a href="/wiki/B_cell" title="B cell">B cell</a>.<sup id="cite_ref-cd81_8-0" class="reference"><a href="#cite_note-cd81-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> On <a href="/wiki/T_cell" title="T cell">T cells</a> CD81 associates with <a href="/wiki/CD4" title="CD4">CD4</a> and <a href="/wiki/CD8" title="CD8">CD8</a> and provides a costimulatory signal with <a href="/wiki/CD3_(immunology)" title="CD3 (immunology)">CD3</a>.<sup id="cite_ref-cd81_8-1" class="reference"><a href="#cite_note-cd81-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Clinical_significance">Clinical significance</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CD81&action=edit&section=3" title="Edit section: Clinical significance"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>This protein plays a critical role in <a href="/wiki/Hepatitis_C" title="Hepatitis C">Hepatitis C</a> attachment and/or cell entry by interacting with virus' E1/E2 glycoproteins heterodimer.<sup id="cite_ref-pmid12913001_9-0" class="reference"><a href="#cite_note-pmid12913001-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> The large extracellular loop of CD81 binds the hepatitis E2 glycoprotein dimer. HCV-E2 and CD81 binding Kd is 1.8 nM. HCV-E2 engaged CD81 is only 30% internalized after 12hr, suggesting CD81 may be primarily an attachment receptor for HCV.<sup id="cite_ref-pmid10775621_10-0" class="reference"><a href="#cite_note-pmid10775621-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </p><p>It also appears to play a role in <a href="/wiki/Liver" title="Liver">liver</a> invasion by <i><a href="/wiki/Plasmodium" title="Plasmodium">Plasmodium</a></i> species.<sup id="cite_ref-pmid18389082_11-0" class="reference"><a href="#cite_note-pmid18389082-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> CD81 is required for <i><a href="/wiki/Plasmodium_vivax" title="Plasmodium vivax">Plasmodium vivax</a></i> sporozoite entry into human hepatocytes and for <i><a href="/wiki/Plasmodium_yoelii" title="Plasmodium yoelii">Plasmodium yoelii</a></i> sporozoite entry into murine hepatocytes.<sup id="cite_ref-pmid12483205_12-0" class="reference"><a href="#cite_note-pmid12483205-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> </p><p>HIV gag proteins use tetraspanin enriched microdomains (containing minimally CD81, CD82, CD63) as a platform for virion assembly and release. Purified HIV produced by MOLT\HIV cells contains CD81. Anti-CD81 antibodies downregulate HIV production 3 fold, however the CD81 protein free virus is more infectious.<sup id="cite_ref-pmid19284574_13-0" class="reference"><a href="#cite_note-pmid19284574-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> Engagement of CD81 lowers the signaling threshold required to trigger T-Cell\CD3 mediated proviral DNA in CD4+ T cells.<sup id="cite_ref-pmid15767432_14-0" class="reference"><a href="#cite_note-pmid15767432-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> </p><p>CD81 appears to play a role in the pathogenesis of influenza.<sup id="cite_ref-He_2013_15-0" class="reference"><a href="#cite_note-He_2013-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Interactions">Interactions</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CD81&action=edit&section=4" title="Edit section: Interactions"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>CD81 has been shown to <a href="/wiki/Protein-protein_interaction" class="mw-redirect" title="Protein-protein interaction">interact</a> with <a href="/wiki/TSPAN4" title="TSPAN4">TSPAN4</a>,<sup id="cite_ref-pmid9360996_16-0" class="reference"><a href="#cite_note-pmid9360996-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup> <a href="/wiki/CD19" title="CD19">CD19</a>,<sup id="cite_ref-pmid1383329_17-0" class="reference"><a href="#cite_note-pmid1383329-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid7636191_18-0" class="reference"><a href="#cite_note-pmid7636191-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid9804823_19-0" class="reference"><a href="#cite_note-pmid9804823-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> <a href="/wiki/CD9" title="CD9">CD9</a>,<sup id="cite_ref-pmid9804823_19-1" class="reference"><a href="#cite_note-pmid9804823-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid8630057_20-0" class="reference"><a href="#cite_note-pmid8630057-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup> <a href="/wiki/PTGFRN" title="PTGFRN">PTGFRN</a>,<sup id="cite_ref-pmid11278880_21-0" class="reference"><a href="#cite_note-pmid11278880-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid11087758_22-0" class="reference"><a href="#cite_note-pmid11087758-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup> <a href="/wiki/CD117" class="mw-redirect" title="CD117">CD117</a><sup id="cite_ref-pmid12036870_23-0" class="reference"><a href="#cite_note-pmid12036870-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup> and <a href="/wiki/CD29" class="mw-redirect" title="CD29">CD29</a>.<sup id="cite_ref-pmid10229664_24-0" class="reference"><a href="#cite_note-pmid10229664-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid12175627_25-0" class="reference"><a href="#cite_note-pmid12175627-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Ligands">Ligands</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CD81&action=edit&section=5" title="Edit section: Ligands"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Benzyl_salicylate" title="Benzyl salicylate">Benzyl salicylate</a><sup id="cite_ref-pmid22740401_26-0" class="reference"><a href="#cite_note-pmid22740401-26"><span class="cite-bracket">[</span>26<span class="cite-bracket">]</span></a></sup> and <a href="/wiki/Terfenadine" title="Terfenadine">terfenadine</a><sup id="cite_ref-pmid18560330_27-0" class="reference"><a href="#cite_note-pmid18560330-27"><span class="cite-bracket">[</span>27<span class="cite-bracket">]</span></a></sup> have been shown to bind to CD81. </p> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CD81&action=edit&section=6" title="Edit section: See also"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Cluster_of_differentiation" title="Cluster of differentiation">Cluster of differentiation</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CD81&action=edit&section=7" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist reflist-columns references-column-width" style="column-width: 35em;"> <ol class="references"> <li id="cite_note-refGRCh38Ensembl-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCh38Ensembl_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000110651">GRCh38: Ensembl release 89: ENSG00000110651</a> – <a href="/wiki/Ensembl_genome_database_project" title="Ensembl genome database project">Ensembl</a>, May 2017</span> </li> <li id="cite_note-refGRCm38Ensembl-2"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCm38Ensembl_2-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCm38Ensembl_2-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCm38Ensembl_2-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Mus_musculus/Gene/Summary?db=core;g=ENSMUSG00000037706">GRCm38: Ensembl release 89: ENSMUSG00000037706</a> – <a href="/wiki/Ensembl_genome_database_project" title="Ensembl genome database project">Ensembl</a>, May 2017</span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=975">"Human PubMed Reference:"</a>. <i>National Center for Biotechnology Information, U.S. National Library of Medicine</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=National+Center+for+Biotechnology+Information%2C+U.S.+National+Library+of+Medicine&rft.atitle=Human+PubMed+Reference%3A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3Fdb%3Dgene%26cmd%3DLink%26LinkName%3Dgene_pubmed%26from_uid%3D975&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=12520">"Mouse PubMed Reference:"</a>. <i>National Center for Biotechnology Information, U.S. National Library of Medicine</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=National+Center+for+Biotechnology+Information%2C+U.S.+National+Library+of+Medicine&rft.atitle=Mouse+PubMed+Reference%3A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3Fdb%3Dgene%26cmd%3DLink%26LinkName%3Dgene_pubmed%26from_uid%3D12520&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-entrez-5"><span class="mw-cite-backlink">^ <a href="#cite_ref-entrez_5-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-entrez_5-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=975">"Entrez Gene: CD81 CD81 molecule"</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Entrez+Gene%3A+CD81+CD81+molecule&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3FDb%3Dgene%26Cmd%3DShowDetailView%26TermToSearch%3D975&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid1650385-6"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid1650385_6-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid1650385_6-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFAndriaHsiehOrenFrancke1991" class="citation journal cs1">Andria ML, Hsieh CL, Oren R, Francke U, Levy S (August 1991). <a rel="nofollow" class="external text" href="http://www.jimmunol.org/cgi/content/abstract/147/3/1030">"Genomic organization and chromosomal localization of the TAPA-1 gene"</a>. <i>Journal of Immunology</i>. <b>147</b> (3): <span class="nowrap">1030–</span>6. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.147.3.1030">10.4049/jimmunol.147.3.1030</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1650385">1650385</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:31032048">31032048</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Immunology&rft.atitle=Genomic+organization+and+chromosomal+localization+of+the+TAPA-1+gene&rft.volume=147&rft.issue=3&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1030-%3C%2Fspan%3E6&rft.date=1991-08&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A31032048%23id-name%3DS2CID&rft_id=info%3Apmid%2F1650385&rft_id=info%3Adoi%2F10.4049%2Fjimmunol.147.3.1030&rft.aulast=Andria&rft.aufirst=ML&rft.au=Hsieh%2C+CL&rft.au=Oren%2C+R&rft.au=Francke%2C+U&rft.au=Levy%2C+S&rft_id=http%3A%2F%2Fwww.jimmunol.org%2Fcgi%2Fcontent%2Fabstract%2F147%2F3%2F1030&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid11673522-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid11673522_7-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFClark_K.L.Zeng_Z.Langford_A.L.Bowen_S.M.2001" class="citation journal cs1">Clark K.L.; Zeng Z.; Langford A.L.; Bowen S.M.; Todd S.C. (November 2001). <a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.167.9.5115">"PGRL is a major CD81-associated protein on lymphocytes and distinguishes a new family of cell surface proteins"</a>. <i>Journal of Immunology</i>. <b>167</b> (9): <span class="nowrap">5115–</span>5121. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.167.9.5115">10.4049/jimmunol.167.9.5115</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11673522">11673522</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Immunology&rft.atitle=PGRL+is+a+major+CD81-associated+protein+on+lymphocytes+and+distinguishes+a+new+family+of+cell+surface+proteins&rft.volume=167&rft.issue=9&rft.pages=%3Cspan+class%3D%22nowrap%22%3E5115-%3C%2Fspan%3E5121&rft.date=2001-11&rft_id=info%3Adoi%2F10.4049%2Fjimmunol.167.9.5115&rft_id=info%3Apmid%2F11673522&rft.au=Clark+K.L.&rft.au=Zeng+Z.&rft.au=Langford+A.L.&rft.au=Bowen+S.M.&rft.au=Todd+S.C.&rft_id=https%3A%2F%2Fdoi.org%2F10.4049%252Fjimmunol.167.9.5115&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-cd81-8"><span class="mw-cite-backlink">^ <a href="#cite_ref-cd81_8-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-cd81_8-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFLevyToddMaecker1998" class="citation journal cs1">Levy S, Todd SC, Maecker HT (1998). "CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system". <i>Annu Rev Immunol</i>. <b>16</b>: <span class="nowrap">89–</span>109. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1146%2Fannurev.immunol.16.1.89">10.1146/annurev.immunol.16.1.89</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9597125">9597125</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Annu+Rev+Immunol&rft.atitle=CD81+%28TAPA-1%29%3A+a+molecule+involved+in+signal+transduction+and+cell+adhesion+in+the+immune+system.&rft.volume=16&rft.pages=%3Cspan+class%3D%22nowrap%22%3E89-%3C%2Fspan%3E109&rft.date=1998&rft_id=info%3Adoi%2F10.1146%2Fannurev.immunol.16.1.89&rft_id=info%3Apmid%2F9597125&rft.aulast=Levy&rft.aufirst=S&rft.au=Todd%2C+SC&rft.au=Maecker%2C+HT&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid12913001-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid12913001_9-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBartoschVitelliGranierGoujon2003" class="citation journal cs1">Bartosch B, Vitelli A, Granier C, Goujon C, Dubuisson J, Pascale S, Scarselli E, Cortese R, Nicosia A, Cosset FL (October 2003). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M305289200">"Cell entry of hepatitis C virus requires a set of co-receptors that include the CD81 tetraspanin and the SR-B1 scavenger receptor"</a>. <i>The Journal of Biological Chemistry</i>. <b>278</b> (43): <span class="nowrap">41624–</span>30. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M305289200">10.1074/jbc.M305289200</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12913001">12913001</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Biological+Chemistry&rft.atitle=Cell+entry+of+hepatitis+C+virus+requires+a+set+of+co-receptors+that+include+the+CD81+tetraspanin+and+the+SR-B1+scavenger+receptor&rft.volume=278&rft.issue=43&rft.pages=%3Cspan+class%3D%22nowrap%22%3E41624-%3C%2Fspan%3E30&rft.date=2003-10&rft_id=info%3Adoi%2F10.1074%2Fjbc.M305289200&rft_id=info%3Apmid%2F12913001&rft.aulast=Bartosch&rft.aufirst=B&rft.au=Vitelli%2C+A&rft.au=Granier%2C+C&rft.au=Goujon%2C+C&rft.au=Dubuisson%2C+J&rft.au=Pascale%2C+S&rft.au=Scarselli%2C+E&rft.au=Cortese%2C+R&rft.au=Nicosia%2C+A&rft.au=Cosset%2C+FL&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.M305289200&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid10775621-10"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid10775621_10-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFPetraccaFalugiGalliNorais2000" class="citation journal cs1">Petracca R, Falugi F, Galli G, Norais N, Rosa D, Campagnoli S, Burgio V, Di Stasio E, Giardina B, Houghton M, Abrignani S, Grandi G (May 2000). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC112005">"Structure-function analysis of hepatitis C virus envelope-CD81 binding"</a>. <i>J. Virol</i>. <b>74</b> (10): <span class="nowrap">4824–</span>30. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1128%2Fjvi.74.10.4824-4830.2000">10.1128/jvi.74.10.4824-4830.2000</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC112005">112005</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10775621">10775621</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Virol.&rft.atitle=Structure-function+analysis+of+hepatitis+C+virus+envelope-CD81+binding&rft.volume=74&rft.issue=10&rft.pages=%3Cspan+class%3D%22nowrap%22%3E4824-%3C%2Fspan%3E30&rft.date=2000-05&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC112005%23id-name%3DPMC&rft_id=info%3Apmid%2F10775621&rft_id=info%3Adoi%2F10.1128%2Fjvi.74.10.4824-4830.2000&rft.aulast=Petracca&rft.aufirst=R&rft.au=Falugi%2C+F&rft.au=Galli%2C+G&rft.au=Norais%2C+N&rft.au=Rosa%2C+D&rft.au=Campagnoli%2C+S&rft.au=Burgio%2C+V&rft.au=Di+Stasio%2C+E&rft.au=Giardina%2C+B&rft.au=Houghton%2C+M&rft.au=Abrignani%2C+S&rft.au=Grandi%2C+G&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC112005&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid18389082-11"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid18389082_11-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFYalaouiZougbédéCharrinSilvie2008" class="citation journal cs1">Yalaoui S, Zougbédé S, Charrin S, Silvie O, Arduise C, Farhati K, Boucheix C, Mazier D, Rubinstein E, Froissard P (February 2008). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279262">"Hepatocyte Permissiveness to Plasmodium Infection Is Conveyed by a Short and Structurally Conserved Region of the CD81 Large Extracellular Domain"</a>. <i>PLOS Pathogens</i>. <b>4</b> (2): e1000010. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1371%2Fjournal.ppat.1000010">10.1371/journal.ppat.1000010</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279262">2279262</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18389082">18389082</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=PLOS+Pathogens&rft.atitle=Hepatocyte+Permissiveness+to+Plasmodium+Infection+Is+Conveyed+by+a+Short+and+Structurally+Conserved+Region+of+the+CD81+Large+Extracellular+Domain&rft.volume=4&rft.issue=2&rft.pages=e1000010&rft.date=2008-02&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2279262%23id-name%3DPMC&rft_id=info%3Apmid%2F18389082&rft_id=info%3Adoi%2F10.1371%2Fjournal.ppat.1000010&rft.aulast=Yalaoui&rft.aufirst=S&rft.au=Zougb%C3%A9d%C3%A9%2C+S&rft.au=Charrin%2C+S&rft.au=Silvie%2C+O&rft.au=Arduise%2C+C&rft.au=Farhati%2C+K&rft.au=Boucheix%2C+C&rft.au=Mazier%2C+D&rft.au=Rubinstein%2C+E&rft.au=Froissard%2C+P&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2279262&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid12483205-12"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid12483205_12-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSilvieRubinsteinFranetichPrenant2003" class="citation journal cs1">Silvie O, Rubinstein E, Franetich JF, Prenant M, Belnoue E, Rénia L, Hannoun L, Eling W, Levy S, Boucheix C, Mazier D (January 2003). "Hepatocyte CD81 is required for <i>Plasmodium falciparum</i> and <i>Plasmodium yoelii</i> sporozoite infectivity". <i>Nat. Med</i>. <b>9</b> (1): <span class="nowrap">93–</span>6. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnm808">10.1038/nm808</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12483205">12483205</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:6290736">6290736</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nat.+Med.&rft.atitle=Hepatocyte+CD81+is+required+for+Plasmodium+falciparum+and+Plasmodium+yoelii+sporozoite+infectivity&rft.volume=9&rft.issue=1&rft.pages=%3Cspan+class%3D%22nowrap%22%3E93-%3C%2Fspan%3E6&rft.date=2003-01&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A6290736%23id-name%3DS2CID&rft_id=info%3Apmid%2F12483205&rft_id=info%3Adoi%2F10.1038%2Fnm808&rft.aulast=Silvie&rft.aufirst=O&rft.au=Rubinstein%2C+E&rft.au=Franetich%2C+JF&rft.au=Prenant%2C+M&rft.au=Belnoue%2C+E&rft.au=R%C3%A9nia%2C+L&rft.au=Hannoun%2C+L&rft.au=Eling%2C+W&rft.au=Levy%2C+S&rft.au=Boucheix%2C+C&rft.au=Mazier%2C+D&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid19284574-13"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid19284574_13-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFGrigorovAttuil-AudenisPerugiNedelec2009" class="citation journal cs1">Grigorov B, Attuil-Audenis V, Perugi F, Nedelec M, Watson S, Pique C, Darlix JL, Conjeaud H, Muriaux D (2009). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657109">"A role for CD81 on the late steps of HIV-1 replication in a chronically infected T cell line"</a>. <i>Retrovirology</i>. <b>6</b>: 28. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1186%2F1742-4690-6-28">10.1186/1742-4690-6-28</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657109">2657109</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/19284574">19284574</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Retrovirology&rft.atitle=A+role+for+CD81+on+the+late+steps+of+HIV-1+replication+in+a+chronically+infected+T+cell+line&rft.volume=6&rft.pages=28&rft.date=2009&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2657109%23id-name%3DPMC&rft_id=info%3Apmid%2F19284574&rft_id=info%3Adoi%2F10.1186%2F1742-4690-6-28&rft.aulast=Grigorov&rft.aufirst=B&rft.au=Attuil-Audenis%2C+V&rft.au=Perugi%2C+F&rft.au=Nedelec%2C+M&rft.au=Watson%2C+S&rft.au=Pique%2C+C&rft.au=Darlix%2C+JL&rft.au=Conjeaud%2C+H&rft.au=Muriaux%2C+D&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2657109&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid15767432-14"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid15767432_14-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFTardifTremblay2005" class="citation journal cs1">Tardif MR, Tremblay MJ (April 2005). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1061526">"Tetraspanin CD81 provides a costimulatory signal resulting in increased human immunodeficiency virus type 1 gene expression in primary CD4+ T lymphocytes through NF-kappaB, NFAT, and AP-1 transduction pathways"</a>. <i>J. Virol</i>. <b>79</b> (7): <span class="nowrap">4316–</span>28. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1128%2FJVI.79.7.4316-4328.2005">10.1128/JVI.79.7.4316-4328.2005</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1061526">1061526</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15767432">15767432</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Virol.&rft.atitle=Tetraspanin+CD81+provides+a+costimulatory+signal+resulting+in+increased+human+immunodeficiency+virus+type+1+gene+expression+in+primary+CD4%2B+T+lymphocytes+through+NF-kappaB%2C+NFAT%2C+and+AP-1+transduction+pathways&rft.volume=79&rft.issue=7&rft.pages=%3Cspan+class%3D%22nowrap%22%3E4316-%3C%2Fspan%3E28&rft.date=2005-04&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1061526%23id-name%3DPMC&rft_id=info%3Apmid%2F15767432&rft_id=info%3Adoi%2F10.1128%2FJVI.79.7.4316-4328.2005&rft.aulast=Tardif&rft.aufirst=MR&rft.au=Tremblay%2C+MJ&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1061526&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-He_2013-15"><span class="mw-cite-backlink"><b><a href="#cite_ref-He_2013_15-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFHeSunBujnyKim2013" class="citation journal cs1">He J, Sun E, Bujny MV, Kim D, Davidson MW, Zhuang X (October 2013). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795033">"Dual Function of CD81 in Influenza Virus Uncoating and Budding"</a>. <i>PLOS Pathog</i>. <b>9</b> (10): e1003701. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1371%2Fjournal.ppat.1003701">10.1371/journal.ppat.1003701</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795033">3795033</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/24130495">24130495</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=PLOS+Pathog.&rft.atitle=Dual+Function+of+CD81+in+Influenza+Virus+Uncoating+and+Budding&rft.volume=9&rft.issue=10&rft.pages=e1003701&rft.date=2013-10&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3795033%23id-name%3DPMC&rft_id=info%3Apmid%2F24130495&rft_id=info%3Adoi%2F10.1371%2Fjournal.ppat.1003701&rft.aulast=He&rft.aufirst=J&rft.au=Sun%2C+E&rft.au=Bujny%2C+MV&rft.au=Kim%2C+D&rft.au=Davidson%2C+MW&rft.au=Zhuang%2C+X&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3795033&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid9360996-16"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid9360996_16-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFTachibanaBodorovaBerditchevskiZutter1997" class="citation journal cs1">Tachibana I, Bodorova J, Berditchevski F, Zutter MM, Hemler ME (Nov 1997). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.272.46.29181">"NAG-2, a novel transmembrane-4 superfamily (TM4SF) protein that complexes with integrins and other TM4SF proteins"</a>. <i>J. Biol. Chem</i>. <b>272</b> (46): <span class="nowrap">29181–</span>9. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.272.46.29181">10.1074/jbc.272.46.29181</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9360996">9360996</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Biol.+Chem.&rft.atitle=NAG-2%2C+a+novel+transmembrane-4+superfamily+%28TM4SF%29+protein+that+complexes+with+integrins+and+other+TM4SF+proteins&rft.volume=272&rft.issue=46&rft.pages=%3Cspan+class%3D%22nowrap%22%3E29181-%3C%2Fspan%3E9&rft.date=1997-11&rft_id=info%3Adoi%2F10.1074%2Fjbc.272.46.29181&rft_id=info%3Apmid%2F9360996&rft.aulast=Tachibana&rft.aufirst=I&rft.au=Bodorova%2C+J&rft.au=Berditchevski%2C+F&rft.au=Zutter%2C+MM&rft.au=Hemler%2C+ME&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.272.46.29181&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid1383329-17"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid1383329_17-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBradburyKansasLevyEvans1992" class="citation journal cs1">Bradbury LE, Kansas GS, Levy S, Evans RL, Tedder TF (Nov 1992). <a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.149.9.2841">"The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules"</a>. <i>J. Immunol</i>. <b>149</b> (9): <span class="nowrap">2841–</span>50. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.149.9.2841">10.4049/jimmunol.149.9.2841</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1383329">1383329</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:23655762">23655762</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Immunol.&rft.atitle=The+CD19%2FCD21+signal+transducing+complex+of+human+B+lymphocytes+includes+the+target+of+antiproliferative+antibody-1+and+Leu-13+molecules&rft.volume=149&rft.issue=9&rft.pages=%3Cspan+class%3D%22nowrap%22%3E2841-%3C%2Fspan%3E50&rft.date=1992-11&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A23655762%23id-name%3DS2CID&rft_id=info%3Apmid%2F1383329&rft_id=info%3Adoi%2F10.4049%2Fjimmunol.149.9.2841&rft.aulast=Bradbury&rft.aufirst=LE&rft.au=Kansas%2C+GS&rft.au=Levy%2C+S&rft.au=Evans%2C+RL&rft.au=Tedder%2C+TF&rft_id=https%3A%2F%2Fdoi.org%2F10.4049%252Fjimmunol.149.9.2841&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid7636191-18"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid7636191_18-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFImaiKakizakiNishimuraYoshie1995" class="citation journal cs1">Imai T, Kakizaki M, Nishimura M, Yoshie O (Aug 1995). "Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82". <i>J. Immunol</i>. <b>155</b> (3): <span class="nowrap">1229–</span>39. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.155.3.1229">10.4049/jimmunol.155.3.1229</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7636191">7636191</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:32942467">32942467</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Immunol.&rft.atitle=Molecular+analyses+of+the+association+of+CD4+with+two+members+of+the+transmembrane+4+superfamily%2C+CD81+and+CD82&rft.volume=155&rft.issue=3&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1229-%3C%2Fspan%3E39&rft.date=1995-08&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A32942467%23id-name%3DS2CID&rft_id=info%3Apmid%2F7636191&rft_id=info%3Adoi%2F10.4049%2Fjimmunol.155.3.1229&rft.aulast=Imai&rft.aufirst=T&rft.au=Kakizaki%2C+M&rft.au=Nishimura%2C+M&rft.au=Yoshie%2C+O&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid9804823-19"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid9804823_19-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid9804823_19-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFHorváthSerruClayBillard1998" class="citation journal cs1">Horváth G, Serru V, Clay D, Billard M, Boucheix C, Rubinstein E (Nov 1998). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.273.46.30537">"CD19 is linked to the integrin-associated tetraspans CD9, CD81, and CD82"</a>. <i>J. Biol. Chem</i>. <b>273</b> (46): <span class="nowrap">30537–</span>43. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.273.46.30537">10.1074/jbc.273.46.30537</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9804823">9804823</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Biol.+Chem.&rft.atitle=CD19+is+linked+to+the+integrin-associated+tetraspans+CD9%2C+CD81%2C+and+CD82&rft.volume=273&rft.issue=46&rft.pages=%3Cspan+class%3D%22nowrap%22%3E30537-%3C%2Fspan%3E43&rft.date=1998-11&rft_id=info%3Adoi%2F10.1074%2Fjbc.273.46.30537&rft_id=info%3Apmid%2F9804823&rft.aulast=Horv%C3%A1th&rft.aufirst=G&rft.au=Serru%2C+V&rft.au=Clay%2C+D&rft.au=Billard%2C+M&rft.au=Boucheix%2C+C&rft.au=Rubinstein%2C+E&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.273.46.30537&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid8630057-20"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid8630057_20-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFRadfordThorneHersey1996" class="citation journal cs1">Radford KJ, Thorne RF, Hersey P (May 1996). "CD63 associates with transmembrane 4 superfamily members, CD9 and CD81, and with beta 1 integrins in human melanoma". <i>Biochem. Biophys. Res. Commun</i>. <b>222</b> (1): <span class="nowrap">13–</span>8. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1006%2Fbbrc.1996.0690">10.1006/bbrc.1996.0690</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8630057">8630057</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Biochem.+Biophys.+Res.+Commun.&rft.atitle=CD63+associates+with+transmembrane+4+superfamily+members%2C+CD9+and+CD81%2C+and+with+beta+1+integrins+in+human+melanoma&rft.volume=222&rft.issue=1&rft.pages=%3Cspan+class%3D%22nowrap%22%3E13-%3C%2Fspan%3E8&rft.date=1996-05&rft_id=info%3Adoi%2F10.1006%2Fbbrc.1996.0690&rft_id=info%3Apmid%2F8630057&rft.aulast=Radford&rft.aufirst=KJ&rft.au=Thorne%2C+RF&rft.au=Hersey%2C+P&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid11278880-21"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid11278880_21-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFCharrinLe_NaourOualidBillard2001" class="citation journal cs1">Charrin S, Le Naour F, Oualid M, Billard M, Faure G, Hanash SM, Boucheix C, Rubinstein E (Apr 2001). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M011297200">"The major CD9 and CD81 molecular partner. Identification and characterization of the complexes"</a>. <i>J. Biol. Chem</i>. <b>276</b> (17): <span class="nowrap">14329–</span>37. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M011297200">10.1074/jbc.M011297200</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11278880">11278880</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Biol.+Chem.&rft.atitle=The+major+CD9+and+CD81+molecular+partner.+Identification+and+characterization+of+the+complexes&rft.volume=276&rft.issue=17&rft.pages=%3Cspan+class%3D%22nowrap%22%3E14329-%3C%2Fspan%3E37&rft.date=2001-04&rft_id=info%3Adoi%2F10.1074%2Fjbc.M011297200&rft_id=info%3Apmid%2F11278880&rft.aulast=Charrin&rft.aufirst=S&rft.au=Le+Naour%2C+F&rft.au=Oualid%2C+M&rft.au=Billard%2C+M&rft.au=Faure%2C+G&rft.au=Hanash%2C+SM&rft.au=Boucheix%2C+C&rft.au=Rubinstein%2C+E&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.M011297200&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid11087758-22"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid11087758_22-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFStippOrlickyHemler2001" class="citation journal cs1">Stipp CS, Orlicky D, Hemler ME (Feb 2001). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M009859200">"FPRP, a major, highly stoichiometric, highly specific CD81- and CD9-associated protein"</a>. <i>J. Biol. Chem</i>. <b>276</b> (7): <span class="nowrap">4853–</span>62. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M009859200">10.1074/jbc.M009859200</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11087758">11087758</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Biol.+Chem.&rft.atitle=FPRP%2C+a+major%2C+highly+stoichiometric%2C+highly+specific+CD81-+and+CD9-associated+protein&rft.volume=276&rft.issue=7&rft.pages=%3Cspan+class%3D%22nowrap%22%3E4853-%3C%2Fspan%3E62&rft.date=2001-02&rft_id=info%3Adoi%2F10.1074%2Fjbc.M009859200&rft_id=info%3Apmid%2F11087758&rft.aulast=Stipp&rft.aufirst=CS&rft.au=Orlicky%2C+D&rft.au=Hemler%2C+ME&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.M009859200&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid12036870-23"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid12036870_23-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFAnzai_NLee_YoungheeYoun_Byung-SFukuda_Seiji2002" class="citation journal cs1">Anzai N; Lee Younghee; Youn Byung-S; Fukuda Seiji; Kim Young-June; Mantel Charlie; Akashi Makoto; Broxmeyer Hal E (Jun 2002). "C-kit associated with the transmembrane 4 superfamily proteins constitutes a functionally distinct subunit in human hematopoietic progenitors". <i>Blood</i>. <b>99</b> (12): <span class="nowrap">4413–</span>21. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1182%2Fblood.V99.12.4413">10.1182/blood.V99.12.4413</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12036870">12036870</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Blood&rft.atitle=C-kit+associated+with+the+transmembrane+4+superfamily+proteins+constitutes+a+functionally+distinct+subunit+in+human+hematopoietic+progenitors&rft.volume=99&rft.issue=12&rft.pages=%3Cspan+class%3D%22nowrap%22%3E4413-%3C%2Fspan%3E21&rft.date=2002-06&rft_id=info%3Adoi%2F10.1182%2Fblood.V99.12.4413&rft_id=info%3Apmid%2F12036870&rft.au=Anzai+N&rft.au=Lee+Younghee&rft.au=Youn+Byung-S&rft.au=Fukuda+Seiji&rft.au=Kim+Young-June&rft.au=Mantel+Charlie&rft.au=Akashi+Makoto&rft.au=Broxmeyer+Hal+E&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid10229664-24"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid10229664_24-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSerruLe_NaourBillardAzorsa1999" class="citation journal cs1">Serru V, Le Naour F, Billard M, Azorsa DO, Lanza F, Boucheix C, Rubinstein E (May 1999). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1220227">"Selective tetraspan-integrin complexes (CD81/alpha4beta1, CD151/alpha3beta1, CD151/alpha6beta1) under conditions disrupting tetraspan interactions"</a>. <i>Biochem. J</i>. <b>340</b> (Pt 1): <span class="nowrap">103–</span>11. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1042%2F0264-6021%3A3400103">10.1042/0264-6021:3400103</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1220227">1220227</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10229664">10229664</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Biochem.+J.&rft.atitle=Selective+tetraspan-integrin+complexes+%28CD81%2Falpha4beta1%2C+CD151%2Falpha3beta1%2C+CD151%2Falpha6beta1%29+under+conditions+disrupting+tetraspan+interactions&rft.volume=340&rft.issue=Pt+1&rft.pages=%3Cspan+class%3D%22nowrap%22%3E103-%3C%2Fspan%3E11&rft.date=1999-05&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1220227%23id-name%3DPMC&rft_id=info%3Apmid%2F10229664&rft_id=info%3Adoi%2F10.1042%2F0264-6021%3A3400103&rft.aulast=Serru&rft.aufirst=V&rft.au=Le+Naour%2C+F&rft.au=Billard%2C+M&rft.au=Azorsa%2C+DO&rft.au=Lanza%2C+F&rft.au=Boucheix%2C+C&rft.au=Rubinstein%2C+E&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1220227&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid12175627-25"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid12175627_25-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFMazzocca_ACarloni_VinicioSciammetta_SilviaCordella_Claudia2002" class="citation journal cs1">Mazzocca A; Carloni Vinicio; Sciammetta Silvia; Cordella Claudia; Pantaleo Pietro; Caldini Anna; Gentilini Paolo; Pinzani Massimo (Sep 2002). "Expression of transmembrane 4 superfamily (TM4SF) proteins and their role in hepatic stellate cell motility and wound healing migration". <i>J. Hepatol</i>. <b>37</b> (3): <span class="nowrap">322–</span>30. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0168-8278%2802%2900175-7">10.1016/S0168-8278(02)00175-7</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12175627">12175627</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Hepatol.&rft.atitle=Expression+of+transmembrane+4+superfamily+%28TM4SF%29+proteins+and+their+role+in+hepatic+stellate+cell+motility+and+wound+healing+migration&rft.volume=37&rft.issue=3&rft.pages=%3Cspan+class%3D%22nowrap%22%3E322-%3C%2Fspan%3E30&rft.date=2002-09&rft_id=info%3Adoi%2F10.1016%2FS0168-8278%2802%2900175-7&rft_id=info%3Apmid%2F12175627&rft.au=Mazzocca+A&rft.au=Carloni+Vinicio&rft.au=Sciammetta+Silvia&rft.au=Cordella+Claudia&rft.au=Pantaleo+Pietro&rft.au=Caldini+Anna&rft.au=Gentilini+Paolo&rft.au=Pinzani+Massimo&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid22740401-26"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid22740401_26-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFRajeshSridharTewsFénéant2012" class="citation journal cs1">Rajesh S, Sridhar P, Tews BA, Fénéant L, Cocquerel L, Ward DG, Berditchevski F, Overduin M (June 2012). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446547">"Structural basis of ligand interactions of the large extracellular domain of tetraspanin CD81"</a>. <i>J Virol</i>. <b>86</b> (18): <span class="nowrap">9606–</span>16. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1128%2FJVI.00559-12">10.1128/JVI.00559-12</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446547">3446547</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/22740401">22740401</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J+Virol&rft.atitle=Structural+basis+of+ligand+interactions+of+the+large+extracellular+domain+of+tetraspanin+CD81&rft.volume=86&rft.issue=18&rft.pages=%3Cspan+class%3D%22nowrap%22%3E9606-%3C%2Fspan%3E16&rft.date=2012-06&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3446547%23id-name%3DPMC&rft_id=info%3Apmid%2F22740401&rft_id=info%3Adoi%2F10.1128%2FJVI.00559-12&rft.aulast=Rajesh&rft.aufirst=S&rft.au=Sridhar%2C+P&rft.au=Tews%2C+BA&rft.au=F%C3%A9n%C3%A9ant%2C+L&rft.au=Cocquerel%2C+L&rft.au=Ward%2C+DG&rft.au=Berditchevski%2C+F&rft.au=Overduin%2C+M&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3446547&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> <li id="cite_note-pmid18560330-27"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid18560330_27-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFHolzerZieglerAlbrechtKronenberger2008" class="citation journal cs1">Holzer M, Ziegler S, Albrecht B, Kronenberger B, Kaul A, Bartenschlager R, Kattner L, Klein CD, Hartmann RW (2008). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245452">"Identification of terfenadine as an inhibitor of human CD81-receptor HCV-E2 interaction: synthesis and structure optimization"</a>. <i>Molecules</i>. <b>13</b> (5): <span class="nowrap">1081–</span>110. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.3390%2Fmolecules13051081">10.3390/molecules13051081</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245452">6245452</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18560330">18560330</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Molecules&rft.atitle=Identification+of+terfenadine+as+an+inhibitor+of+human+CD81-receptor+HCV-E2+interaction%3A+synthesis+and+structure+optimization&rft.volume=13&rft.issue=5&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1081-%3C%2Fspan%3E110&rft.date=2008&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6245452%23id-name%3DPMC&rft_id=info%3Apmid%2F18560330&rft_id=info%3Adoi%2F10.3390%2Fmolecules13051081&rft.aulast=Holzer&rft.aufirst=M&rft.au=Ziegler%2C+S&rft.au=Albrecht%2C+B&rft.au=Kronenberger%2C+B&rft.au=Kaul%2C+A&rft.au=Bartenschlager%2C+R&rft.au=Kattner%2C+L&rft.au=Klein%2C+CD&rft.au=Hartmann%2C+RW&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6245452&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Further_reading">Further reading</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CD81&action=edit&section=8" title="Edit section: Further reading"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239549316">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin refbegin-columns references-column-width" style="column-width: 35em"> <ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBerditchevski_F2002" class="citation journal cs1">Berditchevski F (2002). "Complexes of tetraspanins with integrins: more than meets the eye". <i>J. Cell Sci</i>. <b>114</b> (Pt 23): <span class="nowrap">4143–</span>51. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1242%2Fjcs.114.23.4143">10.1242/jcs.114.23.4143</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11739647">11739647</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Cell+Sci.&rft.atitle=Complexes+of+tetraspanins+with+integrins%3A+more+than+meets+the+eye&rft.volume=114&rft.issue=Pt+23&rft.pages=%3Cspan+class%3D%22nowrap%22%3E4143-%3C%2Fspan%3E51&rft.date=2002&rft_id=info%3Adoi%2F10.1242%2Fjcs.114.23.4143&rft_id=info%3Apmid%2F11739647&rft.au=Berditchevski+F&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFYe_J2007" class="citation journal cs1">Ye J (2007). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959368">"Reliance of Host Cholesterol Metabolic Pathways for the Life Cycle of Hepatitis C Virus"</a>. <i>PLOS Pathog</i>. <b>3</b> (8): e108. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1371%2Fjournal.ppat.0030108">10.1371/journal.ppat.0030108</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959368">1959368</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17784784">17784784</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=PLOS+Pathog.&rft.atitle=Reliance+of+Host+Cholesterol+Metabolic+Pathways+for+the+Life+Cycle+of+Hepatitis+C+Virus&rft.volume=3&rft.issue=8&rft.pages=e108&rft.date=2007&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1959368%23id-name%3DPMC&rft_id=info%3Apmid%2F17784784&rft_id=info%3Adoi%2F10.1371%2Fjournal.ppat.0030108&rft.au=Ye+J&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1959368&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBradburyKansasLevy1992" class="citation journal cs1">Bradbury LE, Kansas GS, Levy S, et al. (1992). <a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.149.9.2841">"The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules"</a>. <i>J. Immunol</i>. <b>149</b> (9): <span class="nowrap">2841–</span>50. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.149.9.2841">10.4049/jimmunol.149.9.2841</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1383329">1383329</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:23655762">23655762</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Immunol.&rft.atitle=The+CD19%2FCD21+signal+transducing+complex+of+human+B+lymphocytes+includes+the+target+of+antiproliferative+antibody-1+and+Leu-13+molecules&rft.volume=149&rft.issue=9&rft.pages=%3Cspan+class%3D%22nowrap%22%3E2841-%3C%2Fspan%3E50&rft.date=1992&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A23655762%23id-name%3DS2CID&rft_id=info%3Apmid%2F1383329&rft_id=info%3Adoi%2F10.4049%2Fjimmunol.149.9.2841&rft.aulast=Bradbury&rft.aufirst=LE&rft.au=Kansas%2C+GS&rft.au=Levy%2C+S&rft_id=https%3A%2F%2Fdoi.org%2F10.4049%252Fjimmunol.149.9.2841&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFAndriaHsiehOren1991" class="citation journal cs1">Andria ML, Hsieh CL, Oren R, et al. (1991). "Genomic organization and chromosomal localization of the TAPA-1 gene". <i>J. Immunol</i>. <b>147</b> (3): <span class="nowrap">1030–</span>6. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.147.3.1030">10.4049/jimmunol.147.3.1030</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1650385">1650385</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:31032048">31032048</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Immunol.&rft.atitle=Genomic+organization+and+chromosomal+localization+of+the+TAPA-1+gene&rft.volume=147&rft.issue=3&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1030-%3C%2Fspan%3E6&rft.date=1991&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A31032048%23id-name%3DS2CID&rft_id=info%3Apmid%2F1650385&rft_id=info%3Adoi%2F10.4049%2Fjimmunol.147.3.1030&rft.aulast=Andria&rft.aufirst=ML&rft.au=Hsieh%2C+CL&rft.au=Oren%2C+R&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFOrenTakahashiDoss1990" class="citation journal cs1">Oren R, Takahashi S, Doss C, et al. (1990). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC360911">"TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins"</a>. <i>Mol. Cell. Biol</i>. <b>10</b> (8): <span class="nowrap">4007–</span>15. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1128%2FMCB.10.8.4007">10.1128/MCB.10.8.4007</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC360911">360911</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1695320">1695320</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Mol.+Cell.+Biol.&rft.atitle=TAPA-1%2C+the+target+of+an+antiproliferative+antibody%2C+defines+a+new+family+of+transmembrane+proteins&rft.volume=10&rft.issue=8&rft.pages=%3Cspan+class%3D%22nowrap%22%3E4007-%3C%2Fspan%3E15&rft.date=1990&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC360911%23id-name%3DPMC&rft_id=info%3Apmid%2F1695320&rft_id=info%3Adoi%2F10.1128%2FMCB.10.8.4007&rft.aulast=Oren&rft.aufirst=R&rft.au=Takahashi%2C+S&rft.au=Doss%2C+C&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC360911&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFLevyNguyenAndriaTakahashi1991" class="citation journal cs1">Levy S, Nguyen VQ, Andria ML, Takahashi S (1991). <a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0021-9258%2818%2998728-4">"Structure and membrane topology of TAPA-1"</a>. <i>J. Biol. Chem</i>. <b>266</b> (22): <span class="nowrap">14597–</span>602. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0021-9258%2818%2998728-4">10.1016/S0021-9258(18)98728-4</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1860863">1860863</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Biol.+Chem.&rft.atitle=Structure+and+membrane+topology+of+TAPA-1&rft.volume=266&rft.issue=22&rft.pages=%3Cspan+class%3D%22nowrap%22%3E14597-%3C%2Fspan%3E602&rft.date=1991&rft_id=info%3Adoi%2F10.1016%2FS0021-9258%2818%2998728-4&rft_id=info%3Apmid%2F1860863&rft.aulast=Levy&rft.aufirst=S&rft.au=Nguyen%2C+VQ&rft.au=Andria%2C+ML&rft.au=Takahashi%2C+S&rft_id=https%3A%2F%2Fdoi.org%2F10.1016%252FS0021-9258%252818%252998728-4&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFTakahashiDossLevyLevy1990" class="citation journal cs1">Takahashi S, Doss C, Levy S, Levy R (1990). <a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.145.7.2207">"TAPA-1, the target of an antiproliferative antibody, is associated on the cell surface with the Leu-13 antigen"</a>. <i>J. Immunol</i>. <b>145</b> (7): <span class="nowrap">2207–</span>13. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.145.7.2207">10.4049/jimmunol.145.7.2207</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/2398277">2398277</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:30999229">30999229</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Immunol.&rft.atitle=TAPA-1%2C+the+target+of+an+antiproliferative+antibody%2C+is+associated+on+the+cell+surface+with+the+Leu-13+antigen&rft.volume=145&rft.issue=7&rft.pages=%3Cspan+class%3D%22nowrap%22%3E2207-%3C%2Fspan%3E13&rft.date=1990&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A30999229%23id-name%3DS2CID&rft_id=info%3Apmid%2F2398277&rft_id=info%3Adoi%2F10.4049%2Fjimmunol.145.7.2207&rft.aulast=Takahashi&rft.aufirst=S&rft.au=Doss%2C+C&rft.au=Levy%2C+S&rft.au=Levy%2C+R&rft_id=https%3A%2F%2Fdoi.org%2F10.4049%252Fjimmunol.145.7.2207&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFMatsumotoMartinCarter1993" class="citation journal cs1">Matsumoto AK, Martin DR, Carter RH, et al. (1993). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191213">"Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes"</a>. <i>J. Exp. Med</i>. <b>178</b> (4): <span class="nowrap">1407–</span>17. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1084%2Fjem.178.4.1407">10.1084/jem.178.4.1407</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191213">2191213</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7690834">7690834</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Exp.+Med.&rft.atitle=Functional+dissection+of+the+CD21%2FCD19%2FTAPA-1%2FLeu-13+complex+of+B+lymphocytes&rft.volume=178&rft.issue=4&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1407-%3C%2Fspan%3E17&rft.date=1993&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2191213%23id-name%3DPMC&rft_id=info%3Apmid%2F7690834&rft_id=info%3Adoi%2F10.1084%2Fjem.178.4.1407&rft.aulast=Matsumoto&rft.aufirst=AK&rft.au=Martin%2C+DR&rft.au=Carter%2C+RH&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2191213&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFNagiraImaiIshikawa1994" class="citation journal cs1">Nagira M, Imai T, Ishikawa I, et al. (1994). "Mouse homologue of C33 antigen (CD82), a member of the transmembrane 4 superfamily: complementary DNA, genomic structure, and expression". <i>Cell. Immunol</i>. <b>157</b> (1): <span class="nowrap">144–</span>57. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1006%2Fcimm.1994.1212">10.1006/cimm.1994.1212</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8039242">8039242</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Cell.+Immunol.&rft.atitle=Mouse+homologue+of+C33+antigen+%28CD82%29%2C+a+member+of+the+transmembrane+4+superfamily%3A+complementary+DNA%2C+genomic+structure%2C+and+expression&rft.volume=157&rft.issue=1&rft.pages=%3Cspan+class%3D%22nowrap%22%3E144-%3C%2Fspan%3E57&rft.date=1994&rft_id=info%3Adoi%2F10.1006%2Fcimm.1994.1212&rft_id=info%3Apmid%2F8039242&rft.aulast=Nagira&rft.aufirst=M&rft.au=Imai%2C+T&rft.au=Ishikawa%2C+I&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFVirtanevaEmiMarken1994" class="citation journal cs1">Virtaneva KI, Emi N, Marken JS, et al. (1994). "Chromosomal localization of three human genes coding for A15, L6, and S5.7 (TAPA1): all members of the transmembrane 4 superfamily of proteins". <i>Immunogenetics</i>. <b>39</b> (5): <span class="nowrap">329–</span>34. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2FBF00189229">10.1007/BF00189229</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8168850">8168850</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:22971645">22971645</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Immunogenetics&rft.atitle=Chromosomal+localization+of+three+human+genes+coding+for+A15%2C+L6%2C+and+S5.7+%28TAPA1%29%3A+all+members+of+the+transmembrane+4+superfamily+of+proteins&rft.volume=39&rft.issue=5&rft.pages=%3Cspan+class%3D%22nowrap%22%3E329-%3C%2Fspan%3E34&rft.date=1994&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A22971645%23id-name%3DS2CID&rft_id=info%3Apmid%2F8168850&rft_id=info%3Adoi%2F10.1007%2FBF00189229&rft.aulast=Virtaneva&rft.aufirst=KI&rft.au=Emi%2C+N&rft.au=Marken%2C+JS&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFRadfordThorneHersey1996" class="citation journal cs1">Radford KJ, Thorne RF, Hersey P (1996). "CD63 associates with transmembrane 4 superfamily members, CD9 and CD81, and with beta 1 integrins in human melanoma". <i>Biochem. Biophys. Res. Commun</i>. <b>222</b> (1): <span class="nowrap">13–</span>8. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1006%2Fbbrc.1996.0690">10.1006/bbrc.1996.0690</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8630057">8630057</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Biochem.+Biophys.+Res.+Commun.&rft.atitle=CD63+associates+with+transmembrane+4+superfamily+members%2C+CD9+and+CD81%2C+and+with+beta+1+integrins+in+human+melanoma&rft.volume=222&rft.issue=1&rft.pages=%3Cspan+class%3D%22nowrap%22%3E13-%3C%2Fspan%3E8&rft.date=1996&rft_id=info%3Adoi%2F10.1006%2Fbbrc.1996.0690&rft_id=info%3Apmid%2F8630057&rft.aulast=Radford&rft.aufirst=KJ&rft.au=Thorne%2C+RF&rft.au=Hersey%2C+P&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSzöllósiHorejsíBene1996" class="citation journal cs1">Szöllósi J, Horejsí V, Bene L, et al. (1996). <a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.157.7.2939">"Supramolecular complexes of MHC class I, MHC class II, CD20, and tetraspan molecules (CD53, CD81, and CD82) at the surface of a B cell line JY"</a>. <i>J. Immunol</i>. <b>157</b> (7): <span class="nowrap">2939–</span>46. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.157.7.2939">10.4049/jimmunol.157.7.2939</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8816400">8816400</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:18389389">18389389</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Immunol.&rft.atitle=Supramolecular+complexes+of+MHC+class+I%2C+MHC+class+II%2C+CD20%2C+and+tetraspan+molecules+%28CD53%2C+CD81%2C+and+CD82%29+at+the+surface+of+a+B+cell+line+JY&rft.volume=157&rft.issue=7&rft.pages=%3Cspan+class%3D%22nowrap%22%3E2939-%3C%2Fspan%3E46&rft.date=1996&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A18389389%23id-name%3DS2CID&rft_id=info%3Apmid%2F8816400&rft_id=info%3Adoi%2F10.4049%2Fjimmunol.157.7.2939&rft.aulast=Sz%C3%B6ll%C3%B3si&rft.aufirst=J&rft.au=Horejs%C3%AD%2C+V&rft.au=Bene%2C+L&rft_id=https%3A%2F%2Fdoi.org%2F10.4049%252Fjimmunol.157.7.2939&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBerditchevskiToliasWong1997" class="citation journal cs1">Berditchevski F, Tolias KF, Wong K, et al. (1997). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.272.5.2595">"A novel link between integrins, transmembrane-4 superfamily proteins (CD63 and CD81), and phosphatidylinositol 4-kinase"</a>. <i>J. Biol. Chem</i>. <b>272</b> (5): <span class="nowrap">2595–</span>8. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.272.5.2595">10.1074/jbc.272.5.2595</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9006891">9006891</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Biol.+Chem.&rft.atitle=A+novel+link+between+integrins%2C+transmembrane-4+superfamily+proteins+%28CD63+and+CD81%29%2C+and+phosphatidylinositol+4-kinase&rft.volume=272&rft.issue=5&rft.pages=%3Cspan+class%3D%22nowrap%22%3E2595-%3C%2Fspan%3E8&rft.date=1997&rft_id=info%3Adoi%2F10.1074%2Fjbc.272.5.2595&rft_id=info%3Apmid%2F9006891&rft.aulast=Berditchevski&rft.aufirst=F&rft.au=Tolias%2C+KF&rft.au=Wong%2C+K&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.272.5.2595&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBerditchevskiChangBodorovaHemler1997" class="citation journal cs1">Berditchevski F, Chang S, Bodorova J, Hemler ME (1997). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.272.46.29174">"Generation of monoclonal antibodies to integrin-associated proteins. Evidence that alpha3beta1 complexes with EMMPRIN/basigin/OX47/M6"</a>. <i>J. Biol. Chem</i>. <b>272</b> (46): <span class="nowrap">29174–</span>80. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.272.46.29174">10.1074/jbc.272.46.29174</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9360995">9360995</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Biol.+Chem.&rft.atitle=Generation+of+monoclonal+antibodies+to+integrin-associated+proteins.+Evidence+that+alpha3beta1+complexes+with+EMMPRIN%2Fbasigin%2FOX47%2FM6&rft.volume=272&rft.issue=46&rft.pages=%3Cspan+class%3D%22nowrap%22%3E29174-%3C%2Fspan%3E80&rft.date=1997&rft_id=info%3Adoi%2F10.1074%2Fjbc.272.46.29174&rft_id=info%3Apmid%2F9360995&rft.aulast=Berditchevski&rft.aufirst=F&rft.au=Chang%2C+S&rft.au=Bodorova%2C+J&rft.au=Hemler%2C+ME&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.272.46.29174&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFTachibanaBodorovaBerditchevski1997" class="citation journal cs1">Tachibana I, Bodorova J, Berditchevski F, et al. (1997). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.272.46.29181">"NAG-2, a novel transmembrane-4 superfamily (TM4SF) protein that complexes with integrins and other TM4SF proteins"</a>. <i>J. Biol. Chem</i>. <b>272</b> (46): <span class="nowrap">29181–</span>9. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.272.46.29181">10.1074/jbc.272.46.29181</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9360996">9360996</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Biol.+Chem.&rft.atitle=NAG-2%2C+a+novel+transmembrane-4+superfamily+%28TM4SF%29+protein+that+complexes+with+integrins+and+other+TM4SF+proteins&rft.volume=272&rft.issue=46&rft.pages=%3Cspan+class%3D%22nowrap%22%3E29181-%3C%2Fspan%3E9&rft.date=1997&rft_id=info%3Adoi%2F10.1074%2Fjbc.272.46.29181&rft_id=info%3Apmid%2F9360996&rft.aulast=Tachibana&rft.aufirst=I&rft.au=Bodorova%2C+J&rft.au=Berditchevski%2C+F&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.272.46.29181&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFHuLeeConnors1998" class="citation journal cs1">Hu RJ, Lee MP, Connors TD, et al. (1998). <a rel="nofollow" class="external text" href="https://doi.org/10.1006%2Fgeno.1997.4981">"A 2.5-Mb transcript map of a tumor-suppressing subchromosomal transferable fragment from 11p15.5, and isolation and sequence analysis of three novel genes"</a>. <i>Genomics</i>. <b>46</b> (1): <span class="nowrap">9–</span>17. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1006%2Fgeno.1997.4981">10.1006/geno.1997.4981</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9403053">9403053</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Genomics&rft.atitle=A+2.5-Mb+transcript+map+of+a+tumor-suppressing+subchromosomal+transferable+fragment+from+11p15.5%2C+and+isolation+and+sequence+analysis+of+three+novel+genes&rft.volume=46&rft.issue=1&rft.pages=%3Cspan+class%3D%22nowrap%22%3E9-%3C%2Fspan%3E17&rft.date=1998&rft_id=info%3Adoi%2F10.1006%2Fgeno.1997.4981&rft_id=info%3Apmid%2F9403053&rft.aulast=Hu&rft.aufirst=RJ&rft.au=Lee%2C+MP&rft.au=Connors%2C+TD&rft_id=https%3A%2F%2Fdoi.org%2F10.1006%252Fgeno.1997.4981&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFPileriUematsuCampagnoli1998" class="citation journal cs1">Pileri P, Uematsu Y, Campagnoli S, et al. (1998). "Binding of hepatitis C virus to CD81". <i>Science</i>. <b>282</b> (5390): <span class="nowrap">938–</span>41. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/1998Sci...282..938P">1998Sci...282..938P</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1126%2Fscience.282.5390.938">10.1126/science.282.5390.938</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9794763">9794763</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Science&rft.atitle=Binding+of+hepatitis+C+virus+to+CD81&rft.volume=282&rft.issue=5390&rft.pages=%3Cspan+class%3D%22nowrap%22%3E938-%3C%2Fspan%3E41&rft.date=1998&rft_id=info%3Apmid%2F9794763&rft_id=info%3Adoi%2F10.1126%2Fscience.282.5390.938&rft_id=info%3Abibcode%2F1998Sci...282..938P&rft.aulast=Pileri&rft.aufirst=P&rft.au=Uematsu%2C+Y&rft.au=Campagnoli%2C+S&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSerruLe_NaourBillard1999" class="citation journal cs1">Serru V, Le Naour F, Billard M, et al. (1999). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1220227">"Selective tetraspan-integrin complexes (CD81/alpha4beta1, CD151/alpha3beta1, CD151/alpha6beta1) under conditions disrupting tetraspan interactions"</a>. <i>Biochem. J</i>. <b>340</b> (Pt 1): <span class="nowrap">103–</span>11. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1042%2F0264-6021%3A3400103">10.1042/0264-6021:3400103</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1220227">1220227</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10229664">10229664</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Biochem.+J.&rft.atitle=Selective+tetraspan-integrin+complexes+%28CD81%2Falpha4beta1%2C+CD151%2Falpha3beta1%2C+CD151%2Falpha6beta1%29+under+conditions+disrupting+tetraspan+interactions&rft.volume=340&rft.issue=Pt+1&rft.pages=%3Cspan+class%3D%22nowrap%22%3E103-%3C%2Fspan%3E11&rft.date=1999&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1220227%23id-name%3DPMC&rft_id=info%3Apmid%2F10229664&rft_id=info%3Adoi%2F10.1042%2F0264-6021%3A3400103&rft.aulast=Serru&rft.aufirst=V&rft.au=Le+Naour%2C+F&rft.au=Billard%2C+M&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1220227&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFTachibanaHemler1999" class="citation journal cs1">Tachibana I, Hemler ME (1999). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2156130">"Role of Transmembrane 4 Superfamily (Tm4sf) Proteins Cd9 and Cd81 in Muscle Cell Fusion and Myotube Maintenance"</a>. <i>J. Cell Biol</i>. <b>146</b> (4): <span class="nowrap">893–</span>904. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1083%2Fjcb.146.4.893">10.1083/jcb.146.4.893</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2156130">2156130</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10459022">10459022</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Cell+Biol.&rft.atitle=Role+of+Transmembrane+4+Superfamily+%28Tm4sf%29+Proteins+Cd9+and+Cd81+in+Muscle+Cell+Fusion+and+Myotube+Maintenance&rft.volume=146&rft.issue=4&rft.pages=%3Cspan+class%3D%22nowrap%22%3E893-%3C%2Fspan%3E904&rft.date=1999&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2156130%23id-name%3DPMC&rft_id=info%3Apmid%2F10459022&rft_id=info%3Adoi%2F10.1083%2Fjcb.146.4.893&rft.aulast=Tachibana&rft.aufirst=I&rft.au=Hemler%2C+ME&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2156130&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFHigginbottomQuinnKuo2000" class="citation journal cs1">Higginbottom A, Quinn ER, Kuo CC, et al. (2000). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC111874">"Identification of Amino Acid Residues in CD81 Critical for Interaction with Hepatitis C Virus Envelope Glycoprotein E2"</a>. <i>J. Virol</i>. <b>74</b> (8): <span class="nowrap">3642–</span>9. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1128%2FJVI.74.8.3642-3649.2000">10.1128/JVI.74.8.3642-3649.2000</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC111874">111874</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10729140">10729140</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Virol.&rft.atitle=Identification+of+Amino+Acid+Residues+in+CD81+Critical+for+Interaction+with+Hepatitis+C+Virus+Envelope+Glycoprotein+E2&rft.volume=74&rft.issue=8&rft.pages=%3Cspan+class%3D%22nowrap%22%3E3642-%3C%2Fspan%3E9&rft.date=2000&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC111874%23id-name%3DPMC&rft_id=info%3Apmid%2F10729140&rft_id=info%3Adoi%2F10.1128%2FJVI.74.8.3642-3649.2000&rft.aulast=Higginbottom&rft.aufirst=A&rft.au=Quinn%2C+ER&rft.au=Kuo%2C+CC&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC111874&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACD81" class="Z3988"></span></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CD81&action=edit&section=9" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?name=CD81+protein%2C+human">CD81+protein,+human</a> at the U.S. National Library of Medicine <a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">Medical Subject Headings</a> (MeSH)</li> <li>Human <a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?db=hg38&singleSearch=knownCanonical&position=CD81"><i>CD81</i></a> genome location and <a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgGene?db=hg38&hgg_type=knownGene&hgg_gene=CD81"><i>CD81</i></a> gene details page in the <a href="/wiki/UCSC_Genome_Browser" title="UCSC Genome Browser">UCSC Genome Browser</a>.</li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul ul{display:inline}.mw-parser-output .hlist .mw-empty-li{display:none}.mw-parser-output .hlist dt::after{content:": "}.mw-parser-output .hlist dd::after,.mw-parser-output .hlist li::after{content:" · ";font-weight:bold}.mw-parser-output .hlist dd:last-child::after,.mw-parser-output .hlist dt:last-child::after,.mw-parser-output .hlist li:last-child::after{content:none}.mw-parser-output .hlist dd dd:first-child::before,.mw-parser-output .hlist dd dt:first-child::before,.mw-parser-output .hlist dd li:first-child::before,.mw-parser-output .hlist dt dd:first-child::before,.mw-parser-output .hlist dt dt:first-child::before,.mw-parser-output .hlist dt li:first-child::before,.mw-parser-output .hlist li dd:first-child::before,.mw-parser-output .hlist li dt:first-child::before,.mw-parser-output .hlist li li:first-child::before{content:" (";font-weight:normal}.mw-parser-output .hlist dd dd:last-child::after,.mw-parser-output .hlist dd dt:last-child::after,.mw-parser-output .hlist dd li:last-child::after,.mw-parser-output .hlist dt dd:last-child::after,.mw-parser-output .hlist dt dt:last-child::after,.mw-parser-output .hlist dt li:last-child::after,.mw-parser-output .hlist li dd:last-child::after,.mw-parser-output .hlist li dt:last-child::after,.mw-parser-output .hlist li li:last-child::after{content:")";font-weight:normal}.mw-parser-output .hlist ol{counter-reset:listitem}.mw-parser-output .hlist ol>li{counter-increment:listitem}.mw-parser-output .hlist ol>li::before{content:" "counter(listitem)"\a0 "}.mw-parser-output .hlist dd ol>li:first-child::before,.mw-parser-output .hlist dt ol>li:first-child::before,.mw-parser-output .hlist li ol>li:first-child::before{content:" ("counter(listitem)"\a0 "}</style><style data-mw-deduplicate="TemplateStyles:r1236075235">.mw-parser-output .navbox{box-sizing:border-box;border:1px solid #a2a9b1;width:100%;clear:both;font-size:88%;text-align:center;padding:1px;margin:1em auto 0}.mw-parser-output .navbox .navbox{margin-top:0}.mw-parser-output .navbox+.navbox,.mw-parser-output .navbox+.navbox-styles+.navbox{margin-top:-1px}.mw-parser-output .navbox-inner,.mw-parser-output .navbox-subgroup{width:100%}.mw-parser-output .navbox-group,.mw-parser-output .navbox-title,.mw-parser-output .navbox-abovebelow{padding:0.25em 1em;line-height:1.5em;text-align:center}.mw-parser-output .navbox-group{white-space:nowrap;text-align:right}.mw-parser-output .navbox,.mw-parser-output .navbox-subgroup{background-color:#fdfdfd}.mw-parser-output .navbox-list{line-height:1.5em;border-color:#fdfdfd}.mw-parser-output .navbox-list-with-group{text-align:left;border-left-width:2px;border-left-style:solid}.mw-parser-output tr+tr>.navbox-abovebelow,.mw-parser-output tr+tr>.navbox-group,.mw-parser-output tr+tr>.navbox-image,.mw-parser-output tr+tr>.navbox-list{border-top:2px solid #fdfdfd}.mw-parser-output .navbox-title{background-color:#ccf}.mw-parser-output .navbox-abovebelow,.mw-parser-output .navbox-group,.mw-parser-output .navbox-subgroup .navbox-title{background-color:#ddf}.mw-parser-output .navbox-subgroup .navbox-group,.mw-parser-output .navbox-subgroup .navbox-abovebelow{background-color:#e6e6ff}.mw-parser-output .navbox-even{background-color:#f7f7f7}.mw-parser-output .navbox-odd{background-color:transparent}.mw-parser-output .navbox .hlist td dl,.mw-parser-output .navbox .hlist td ol,.mw-parser-output .navbox .hlist td ul,.mw-parser-output .navbox td.hlist dl,.mw-parser-output .navbox td.hlist ol,.mw-parser-output .navbox td.hlist ul{padding:0.125em 0}.mw-parser-output .navbox .navbar{display:block;font-size:100%}.mw-parser-output .navbox-title .navbar{float:left;text-align:left;margin-right:0.5em}body.skin--responsive .mw-parser-output .navbox-image img{max-width:none!important}@media print{body.ns-0 .mw-parser-output .navbox{display:none!important}}</style></div><div role="navigation" class="navbox" aria-labelledby="PDB_gallery11" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e7dcc3;color:inherit;"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><style data-mw-deduplicate="TemplateStyles:r1239400231">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}html.skin-theme-clientpref-night .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:PDB_Gallery" title="Template:PDB Gallery"><abbr title="View this template" style="color:inherit">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:PDB_Gallery" title="Template talk:PDB Gallery"><abbr title="Discuss this template" style="color:inherit">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:PDB_Gallery" title="Special:EditPage/Template:PDB Gallery"><abbr title="Edit this template" style="color:inherit">e</abbr></a></li></ul></div><div id="PDB_gallery11" style="font-size:114%;margin:0 4em">PDB gallery</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><ul class="gallery mw-gallery-traditional nochecker" style="line-height:130%"> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1g8q_EBI.jpg" class="mw-file-description" title="1g8q: CRYSTAL STRUCTURE OF HUMAN CD81 EXTRACELLULAR DOMAIN, A RECEPTOR FOR HEPATITIS C VIRUS"><img alt="1g8q: CRYSTAL STRUCTURE OF HUMAN CD81 EXTRACELLULAR DOMAIN, A RECEPTOR FOR HEPATITIS C VIRUS" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e0/PDB_1g8q_EBI.jpg/180px-PDB_1g8q_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e0/PDB_1g8q_EBI.jpg/270px-PDB_1g8q_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e0/PDB_1g8q_EBI.jpg/360px-PDB_1g8q_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1g8q</b>: CRYSTAL STRUCTURE OF HUMAN CD81 EXTRACELLULAR DOMAIN, A RECEPTOR FOR HEPATITIS C VIRUS</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1iv5_EBI.jpg" class="mw-file-description" title="1iv5: New Crystal Form of Human CD81 Large Extracellular Loop."><img alt="1iv5: New Crystal Form of Human CD81 Large Extracellular Loop." src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a0/PDB_1iv5_EBI.jpg/180px-PDB_1iv5_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a0/PDB_1iv5_EBI.jpg/270px-PDB_1iv5_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a0/PDB_1iv5_EBI.jpg/360px-PDB_1iv5_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1iv5</b>: New Crystal Form of Human CD81 Large Extracellular Loop.</div> </li> </ul></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="Proteins:_clusters_of_differentiation_(see_also_list_of_human_clusters_of_differentiation)188" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e7dcc3"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231" /><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Clusters_of_differentiation" title="Template:Clusters of differentiation"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Clusters_of_differentiation" title="Template talk:Clusters of differentiation"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Clusters_of_differentiation" title="Special:EditPage/Template:Clusters of differentiation"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Proteins:_clusters_of_differentiation_(see_also_list_of_human_clusters_of_differentiation)188" style="font-size:114%;margin:0 4em"><a href="/wiki/Protein" title="Protein">Proteins</a>: <a href="/wiki/Cluster_of_differentiation" title="Cluster of differentiation">clusters of differentiation</a> (see also <a href="/wiki/List_of_human_clusters_of_differentiation" title="List of human clusters of differentiation">list of human clusters of differentiation</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">1–50</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD1" title="CD1">CD1</a> <ul><li><a href="/wiki/Group_1_CD1" class="mw-redirect" title="Group 1 CD1">a-c</a></li> <li><a href="/wiki/CD1A" title="CD1A">1A</a></li> <li><a href="/wiki/CD1b" title="CD1b">1B</a></li> <li><a href="/wiki/CD1D" title="CD1D">1D</a></li> <li><a href="/wiki/CD1E" title="CD1E">1E</a></li></ul></li> <li><a href="/wiki/CD2" title="CD2">CD2</a></li> <li><a href="/wiki/CD3_(immunology)" title="CD3 (immunology)">CD3</a> <ul><li><a href="/wiki/CD3G" title="CD3G">γ</a></li> <li><a href="/wiki/CD3D" title="CD3D">δ</a></li> <li><a href="/wiki/CD3E" class="mw-redirect" title="CD3E">ε</a></li></ul></li> <li><a href="/wiki/CD4" title="CD4">CD4</a></li> <li><a href="/wiki/CD5_(protein)" title="CD5 (protein)">CD5</a></li> <li><a href="/wiki/CD6" title="CD6">CD6</a></li> <li><a href="/wiki/CD7" title="CD7">CD7</a></li> <li><a href="/wiki/CD8" title="CD8">CD8</a> <ul><li><a href="/wiki/CD8A" title="CD8A">a</a></li></ul></li> <li><a href="/wiki/CD9" title="CD9">CD9</a></li> <li><a href="/wiki/Neprilysin" title="Neprilysin">CD10</a></li> <li><i>CD11</i> <ul><li><a href="/wiki/CD11a" class="mw-redirect" title="CD11a">a</a></li> <li><a href="/wiki/Integrin_alpha_M" title="Integrin alpha M">b</a></li> <li><a href="/wiki/CD11c" class="mw-redirect" title="CD11c">c</a></li> <li><a href="/wiki/ITGAD" class="mw-redirect" title="ITGAD">d</a></li></ul></li> <li><a href="/wiki/Alanine_aminopeptidase" title="Alanine aminopeptidase">CD13</a></li> <li><a href="/wiki/CD14" title="CD14">CD14</a></li> <li><a href="/wiki/CD15" class="mw-redirect" title="CD15">CD15</a></li> <li><a href="/wiki/CD16" title="CD16">CD16</a> <ul><li><a href="/wiki/FCGR3A" title="FCGR3A">A</a></li> <li><a href="/wiki/FCGR3B" title="FCGR3B">B</a></li></ul></li> <li><a href="/wiki/CD18" class="mw-redirect" title="CD18">CD18</a></li> <li><a href="/wiki/CD19" title="CD19">CD19</a></li> <li><a href="/wiki/CD20" title="CD20">CD20</a></li> <li><a href="/wiki/Complement_receptor_2" title="Complement receptor 2">CD21</a></li> <li><a href="/wiki/CD22" title="CD22">CD22</a></li> <li><a href="/wiki/CD23" title="CD23">CD23</a></li> <li><a href="/wiki/CD24" title="CD24">CD24</a></li> <li><a href="/wiki/IL2RA" title="IL2RA">CD25</a></li> <li><a href="/wiki/Dipeptidyl_peptidase-4" title="Dipeptidyl peptidase-4">CD26</a></li> <li><a href="/wiki/CD27" title="CD27">CD27</a></li> <li><a href="/wiki/CD28" title="CD28">CD28</a></li> <li><a href="/wiki/Integrin_beta_1" title="Integrin beta 1">CD29</a></li> <li><a href="/wiki/CD30" title="CD30">CD30</a></li> <li><a href="/wiki/CD31" title="CD31">CD31</a></li> <li><a href="/wiki/CD32" title="CD32">CD32</a> <ul><li><a href="/wiki/FCGR2A" title="FCGR2A">A</a></li> <li><a href="/wiki/FCGR2B" title="FCGR2B">B</a></li></ul></li> <li><a href="/wiki/CD33" title="CD33">CD33</a></li> <li><a href="/wiki/CD34" title="CD34">CD34</a></li> <li><a href="/wiki/Complement_receptor_1" title="Complement receptor 1">CD35</a></li> <li><a href="/wiki/CD36" title="CD36">CD36</a></li> <li><a href="/wiki/CD37" title="CD37">CD37</a></li> <li><a href="/wiki/CD38" title="CD38">CD38</a></li> <li><a href="/wiki/ENTPD1" title="ENTPD1">CD39</a></li> <li><a href="/wiki/CD40_(protein)" title="CD40 (protein)">CD40</a></li> <li><a href="/wiki/ITGA2B" class="mw-redirect" title="ITGA2B">CD41</a></li> <li><a href="/wiki/Glycoprotein_Ib" title="Glycoprotein Ib">CD42</a> <ul><li><a href="/wiki/Glycoprotein_IX" title="Glycoprotein IX">a</a></li> <li><a href="/wiki/GP1BA" title="GP1BA">b</a></li> <li><a href="/wiki/GP1BB" title="GP1BB">c</a></li> <li><a href="/wiki/GP5_(gene)" title="GP5 (gene)">d</a></li></ul></li> <li><a href="/wiki/CD43" title="CD43">CD43</a></li> <li><a href="/wiki/CD44" title="CD44">CD44</a></li> <li><a href="/wiki/PTPRC" title="PTPRC">CD45</a></li> <li><a href="/wiki/CD46" title="CD46">CD46</a></li> <li><a href="/wiki/CD47" title="CD47">CD47</a></li> <li><a href="/wiki/CD48" title="CD48">CD48</a></li> <li><i>CD49</i> <ul><li><a href="/wiki/CD49a" class="mw-redirect" title="CD49a">a</a></li> <li><a href="/wiki/CD49b" class="mw-redirect" title="CD49b">b</a></li> <li><a href="/wiki/CD49c" class="mw-redirect" title="CD49c">c</a></li> <li><a href="/wiki/CD49d" class="mw-redirect" title="CD49d">d</a></li> <li><a href="/wiki/ITGA5" class="mw-redirect" title="ITGA5">e</a></li> <li><a href="/wiki/ITGA6" class="mw-redirect" title="ITGA6">f</a></li></ul></li> <li><a href="/wiki/ICAM3" title="ICAM3">CD50</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">51–100</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/ITGAV" class="mw-redirect" title="ITGAV">CD51</a></li> <li><a href="/wiki/CD52" title="CD52">CD52</a></li> <li><a href="/wiki/CD53" title="CD53">CD53</a></li> <li><a href="/wiki/ICAM-1" title="ICAM-1">CD54</a></li> <li><a href="/wiki/Decay-accelerating_factor" title="Decay-accelerating factor">CD55</a></li> <li><a href="/wiki/Neural_cell_adhesion_molecule" title="Neural cell adhesion molecule">CD56</a></li> <li><a href="/wiki/B3GAT1" title="B3GAT1">CD57</a></li> <li><a href="/wiki/CD58" title="CD58">CD58</a></li> <li><a href="/wiki/CD59" title="CD59">CD59</a></li> <li><a href="/wiki/CD61" class="mw-redirect" title="CD61">CD61</a></li> <li><a href="/wiki/Selectin" title="Selectin">CD62</a> <ul><li><a href="/wiki/E-selectin" title="E-selectin">E</a></li> <li><a href="/wiki/L-selectin" title="L-selectin">L</a></li> <li><a href="/wiki/P-selectin" title="P-selectin">P</a></li></ul></li> <li><a href="/wiki/CD63" title="CD63">CD63</a></li> <li><a href="/wiki/CD64_(biology)" title="CD64 (biology)">CD64</a> <ul><li><a href="/wiki/FCGR1A" title="FCGR1A">A</a></li> <li><a href="/wiki/FCGR1B" class="mw-redirect" title="FCGR1B">B</a></li> <li><a href="/wiki/FCGR1C" class="mw-redirect" title="FCGR1C">C</a></li></ul></li> <li><a href="/wiki/Carcinoembryonic_antigen" title="Carcinoembryonic antigen">CD66</a> <ul><li><a href="/wiki/CEACAM1" title="CEACAM1">a</a></li> <li><a href="/wiki/CEACAM8" title="CEACAM8">b</a></li> <li><a href="/wiki/CEACAM6" title="CEACAM6">c</a></li> <li><a href="/wiki/CEACAM3" title="CEACAM3">d</a></li> <li><a href="/wiki/CEACAM5" title="CEACAM5">e</a></li> <li><a href="/wiki/PSG1_(gene)" class="mw-redirect" title="PSG1 (gene)">f</a></li></ul></li> <li><a href="/wiki/CD68" title="CD68">CD68</a></li> <li><a href="/wiki/CD69" title="CD69">CD69</a></li> <li><a href="/wiki/CD70" title="CD70">CD70</a></li> <li><a href="/wiki/TFRC" class="mw-redirect" title="TFRC">CD71</a></li> <li><a href="/wiki/CD72" title="CD72">CD72</a></li> <li><a href="/wiki/NT5E" title="NT5E">CD73</a></li> <li><a href="/wiki/CD74" title="CD74">CD74</a></li> <li><a href="/wiki/CD78" title="CD78">CD78</a></li> <li><a href="/wiki/CD79" title="CD79">CD79</a> <ul><li><a href="/wiki/CD79A" title="CD79A">a</a></li> <li><a href="/wiki/CD79B" title="CD79B">b</a></li></ul></li> <li><a href="/wiki/CD80" title="CD80">CD80</a></li> <li><a class="mw-selflink selflink">CD81</a></li> <li><a href="/wiki/CD82_(gene)" title="CD82 (gene)">CD82</a></li> <li><a href="/wiki/CD83" title="CD83">CD83</a></li> <li><a href="/wiki/CD84" title="CD84">CD84</a></li> <li><i>CD85</i> <ul><li><a href="/wiki/LILRB3" title="LILRB3">a</a></li> <li><a href="/wiki/LILRB2" title="LILRB2">d</a></li> <li><a href="/wiki/LILRA3" title="LILRA3">e</a></li> <li><a href="/wiki/LILRA2" title="LILRA2">h</a></li> <li><a href="/wiki/LILRB1" title="LILRB1">j</a></li> <li><a href="/wiki/LILRB4" title="LILRB4">k</a></li></ul></li> <li><a href="/wiki/CD86" title="CD86">CD86</a></li> <li><a href="/wiki/Urokinase_receptor" title="Urokinase receptor">CD87</a></li> <li><a href="/wiki/C5a_receptor" title="C5a receptor">CD88</a></li> <li><a href="/wiki/FCAR" title="FCAR">CD89</a></li> <li><a href="/wiki/CD90" title="CD90">CD90</a></li> <li><a href="/wiki/LRP1" title="LRP1">CD91</a> - <a href="/wiki/SLC44A1" class="mw-redirect" title="SLC44A1">CD92</a></li> <li><a href="/wiki/CD93" title="CD93">CD93</a></li> <li><a href="/wiki/KLRD1" title="KLRD1">CD94</a></li> <li><a href="/wiki/Fas_receptor" title="Fas receptor">CD95</a></li> <li><a href="/wiki/CD96" title="CD96">CD96</a></li> <li><a href="/wiki/CD97" title="CD97">CD97</a></li> <li><a href="/wiki/CD98" title="CD98">CD98</a></li> <li><a href="/wiki/CD99" title="CD99">CD99</a></li> <li><a href="/wiki/SEMA4D" title="SEMA4D">CD100</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">101–150</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/IGSF2" title="IGSF2">CD101</a></li> <li><a href="/wiki/ICAM2" title="ICAM2">CD102</a></li> <li><a href="/wiki/ITGAE" title="ITGAE">CD103</a></li> <li><a href="/wiki/ITGB4" class="mw-redirect" title="ITGB4">CD104</a></li> <li><a href="/wiki/Endoglin" title="Endoglin">CD105</a></li> <li><a href="/wiki/VCAM-1" title="VCAM-1">CD106</a></li> <li><i>CD107</i> <ul><li><a href="/wiki/LAMP1" title="LAMP1">a</a></li> <li><a href="/wiki/LAMP2" title="LAMP2">b</a></li></ul></li> <li><a href="/wiki/SEMA7A" title="SEMA7A">CD108</a></li> <li><a href="/wiki/CD109" title="CD109">CD109</a></li> <li><a href="/wiki/Myeloproliferative_leukemia_virus_oncogene" class="mw-redirect" title="Myeloproliferative leukemia virus oncogene">CD110</a></li> <li><a href="/wiki/PVRL1" class="mw-redirect" title="PVRL1">CD111</a></li> <li><a href="/wiki/PVRL2" class="mw-redirect" title="PVRL2">CD112</a></li> <li><a href="/wiki/PVRL3" class="mw-redirect" title="PVRL3">CD113</a></li> <li><a href="/wiki/Granulocyte_colony-stimulating_factor_receptor" title="Granulocyte colony-stimulating factor receptor">CD114</a></li> <li><a href="/wiki/Colony_stimulating_factor_1_receptor" title="Colony stimulating factor 1 receptor">CD115</a></li> <li><a href="/wiki/Granulocyte_macrophage_colony-stimulating_factor_receptor" class="mw-redirect" title="Granulocyte macrophage colony-stimulating factor receptor">CD116</a></li> <li><a href="/wiki/KIT_(gene)" title="KIT (gene)">CD117</a></li> <li><a href="/wiki/Leukemia_inhibitory_factor_receptor" title="Leukemia inhibitory factor receptor">CD118</a></li> <li><a href="/wiki/Interferon_gamma_receptor_1" title="Interferon gamma receptor 1">CD119</a></li> <li><a href="/wiki/CD120" title="CD120">CD120</a> <ul><li><a href="/wiki/TNFRSF1A" class="mw-redirect" title="TNFRSF1A">a</a></li> <li><a href="/wiki/TNFRSF1B" class="mw-redirect" title="TNFRSF1B">b</a></li></ul></li> <li><i>CD121</i> <ul><li><a href="/wiki/Interleukin_1_receptor,_type_I" title="Interleukin 1 receptor, type I">a</a></li> <li><a href="/wiki/Interleukin_1_receptor,_type_II" title="Interleukin 1 receptor, type II">b</a></li></ul></li> <li><a href="/wiki/IL2RB" title="IL2RB">CD122</a></li> <li><a href="/wiki/IL3RA" title="IL3RA">CD123</a></li> <li><a href="/wiki/Interleukin-4_receptor" title="Interleukin-4 receptor">CD124</a></li> <li><a href="/wiki/Interleukin_5_receptor_alpha_subunit" title="Interleukin 5 receptor alpha subunit">CD125</a></li> <li><a href="/wiki/Interleukin-6_receptor" title="Interleukin-6 receptor">CD126</a></li> <li><a href="/wiki/Interleukin-7_receptor" title="Interleukin-7 receptor">CD127</a></li> <li><a href="/wiki/Interleukin-9_receptor" title="Interleukin-9 receptor">CD129</a></li> <li><a href="/wiki/Glycoprotein_130" title="Glycoprotein 130">CD130</a></li> <li><a href="/wiki/CSF2RB" title="CSF2RB">CD131</a></li> <li><a href="/wiki/Common_gamma_chain" title="Common gamma chain">CD132</a></li> <li><a href="/wiki/CD133" title="CD133">CD133</a></li> <li><a href="/wiki/CD134" title="CD134">CD134</a></li> <li><a href="/wiki/CD135" title="CD135">CD135</a></li> <li><a href="/wiki/MST1R" title="MST1R">CD136</a></li> <li><a href="/wiki/CD137" title="CD137">CD137</a></li> <li><a href="/wiki/Syndecan_1" title="Syndecan 1">CD138</a></li> <li><a href="/wiki/PDGFRB" title="PDGFRB">CD140b</a></li> <li><a href="/wiki/Thrombomodulin" title="Thrombomodulin">CD141</a></li> <li><a href="/wiki/Tissue_factor" title="Tissue factor">CD142</a></li> <li><a href="/wiki/Angiotensin-converting_enzyme" title="Angiotensin-converting enzyme">CD143</a></li> <li><a href="/wiki/VE-cadherin" title="VE-cadherin">CD144</a></li> <li><a href="/wiki/CD146" title="CD146">CD146</a></li> <li><a href="/wiki/Basigin" title="Basigin">CD147</a></li> <li><a href="/wiki/PTPRJ" title="PTPRJ">CD148</a></li> <li><a href="/wiki/SLAMF1" title="SLAMF1">CD150</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">151–200</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD151" title="CD151">CD151</a></li> <li><a href="/wiki/CTLA-4" class="mw-redirect" title="CTLA-4">CD152</a></li> <li><a href="/wiki/CD153" title="CD153">CD153</a></li> <li><a href="/wiki/CD154" title="CD154">CD154</a></li> <li><a href="/wiki/CD155" title="CD155">CD155</a></li> <li><i>CD156</i> <ul><li><a href="/wiki/ADAM8" title="ADAM8">a</a></li> <li><a href="/wiki/ADAM17" title="ADAM17">b</a></li> <li><a href="/wiki/ADAM10" title="ADAM10">c</a></li></ul></li> <li><a href="/wiki/BST1" title="BST1">CD157</a></li> <li><i>CD158</i> (<a href="/wiki/KIR2DL1" title="KIR2DL1">a</a></li> <li><a href="/wiki/KIR2DL4" title="KIR2DL4">d</a></li> <li><a href="/wiki/KIR3DL1" title="KIR3DL1">e</a></li> <li><a href="/wiki/KIR2DS4" title="KIR2DS4">i</a></li> <li><a href="/wiki/KIR3DL2" title="KIR3DL2">k</a>)</li> <li><i>CD159</i> <ul><li><a href="/wiki/NKG2" title="NKG2">a</a></li> <li><a href="/wiki/KLRC2" title="KLRC2">c</a></li></ul></li> <li><a href="/wiki/CD160" title="CD160">CD160</a></li> <li><a href="/wiki/KLRB1" title="KLRB1">CD161</a></li> <li><a href="/wiki/P-selectin_glycoprotein_ligand-1" title="P-selectin glycoprotein ligand-1">CD162</a></li> <li><a href="/wiki/CD163" title="CD163">CD163</a></li> <li><a href="/wiki/CD164" title="CD164">CD164</a></li> <li><a href="/wiki/ALCAM" title="ALCAM">CD166</a></li> <li><i>CD167</i> <ul><li><a href="/wiki/DDR1" title="DDR1">a</a></li> <li><a href="/wiki/Discoidin_domain-containing_receptor_2" title="Discoidin domain-containing receptor 2">b</a></li></ul></li> <li><a href="/wiki/Hyaluronan-mediated_motility_receptor" title="Hyaluronan-mediated motility receptor">CD168</a></li> <li><a href="/wiki/Sialoadhesin" title="Sialoadhesin">CD169</a></li> <li><a href="/wiki/SIGLEC5" title="SIGLEC5">CD170</a></li> <li><a href="/wiki/L1_(protein)" title="L1 (protein)">CD171</a></li> <li><i>CD172</i> <ul><li><a href="/wiki/Signal-regulatory_protein_alpha" title="Signal-regulatory protein alpha">a</a></li> <li><a href="/wiki/SIRPB1" title="SIRPB1">b</a></li> <li><a href="/wiki/SIRPG" title="SIRPG">g</a></li></ul></li> <li><a href="/wiki/Fucosyltransferase_3" title="Fucosyltransferase 3">CD174</a></li> <li><a href="/wiki/CD177" title="CD177">CD177</a></li> <li><a href="/wiki/Fas_ligand" title="Fas ligand">CD178</a></li> <li><i>CD179</i> <ul><li><a href="/wiki/VPREB1" title="VPREB1">a</a></li> <li><a href="/wiki/IGLL1" title="IGLL1">b</a></li></ul></li> <li><a href="/wiki/CD180" title="CD180">CD180</a></li> <li><a href="/wiki/Interleukin_8_receptor,_alpha" title="Interleukin 8 receptor, alpha">CD181</a></li> <li><a href="/wiki/Interleukin_8_receptor,_beta" title="Interleukin 8 receptor, beta">CD182</a></li> <li><a href="/wiki/CXCR3" title="CXCR3">CD183</a></li> <li><a href="/wiki/CXCR4" title="CXCR4">CD184</a></li> <li><a href="/wiki/CXCR5" title="CXCR5">CD185</a></li> <li><a href="/wiki/CXCR6" title="CXCR6">CD186</a></li> <li><a href="/wiki/CCR1" title="CCR1">CD191</a></li> <li><a href="/wiki/CCR2" title="CCR2">CD192</a></li> <li><a href="/wiki/CCR3_(gene)" title="CCR3 (gene)">CD193</a></li> <li><a href="/wiki/CCR4" title="CCR4">CD194</a></li> <li><a href="/wiki/CCR5" title="CCR5">CD195</a></li> <li><a href="/wiki/C-C_chemokine_receptor_type_6" title="C-C chemokine receptor type 6">CD196</a></li> <li><a href="/wiki/C-C_chemokine_receptor_type_7" title="C-C chemokine receptor type 7">CD197</a></li> <li><a href="/wiki/CCR8_(gene)" title="CCR8 (gene)">CDw198</a></li> <li><a href="/wiki/CCR9" title="CCR9">CDw199</a></li> <li><a href="/wiki/CD200" title="CD200">CD200</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">201–250</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Endothelial_protein_C_receptor" title="Endothelial protein C receptor">CD201</a></li> <li><a href="/wiki/TEK_tyrosine_kinase" title="TEK tyrosine kinase">CD202b</a></li> <li><a href="/wiki/MSR1" title="MSR1">CD204</a></li> <li><a href="/wiki/LY75" class="mw-redirect" title="LY75">CD205</a></li> <li><a href="/wiki/Mannose_receptor" title="Mannose receptor">CD206</a></li> <li><a href="/wiki/CD207" class="mw-redirect" title="CD207">CD207</a></li> <li><a href="/wiki/LAMP3" title="LAMP3">CD208</a></li> <li><a href="/wiki/DC-SIGN" title="DC-SIGN">CD209</a></li> <li><i>CDw210</i> <ul><li><a href="/wiki/Interleukin_10_receptor,_alpha_subunit" title="Interleukin 10 receptor, alpha subunit">a</a></li> <li><a href="/wiki/Interleukin_10_receptor,_beta_subunit" title="Interleukin 10 receptor, beta subunit">b</a></li></ul></li> <li><a href="/wiki/Interleukin_12_receptor,_beta_1_subunit" title="Interleukin 12 receptor, beta 1 subunit">CD212</a></li> <li><i>CD213a</i> <ul><li><a href="/wiki/IL13RA1" class="mw-redirect" title="IL13RA1">1</a></li> <li><a href="/wiki/IL13RA2" title="IL13RA2">2</a></li></ul></li> <li><a href="/wiki/IL17RA" title="IL17RA">CD217</a></li> <li><i>CD218</i> (<a href="/wiki/IL18R1" title="IL18R1">a</a></li> <li><a href="/wiki/IL18RAP" title="IL18RAP">b</a>)</li> <li><a href="/wiki/Insulin_receptor" title="Insulin receptor">CD220</a></li> <li><a href="/wiki/Insulin-like_growth_factor_1_receptor" title="Insulin-like growth factor 1 receptor">CD221</a></li> <li><a href="/wiki/Insulin-like_growth_factor_2_receptor" title="Insulin-like growth factor 2 receptor">CD222</a></li> <li><a href="/wiki/LAG3" class="mw-redirect" title="LAG3">CD223</a></li> <li><a href="/wiki/GGT1" class="mw-redirect" title="GGT1">CD224</a></li> <li><a href="/wiki/IFITM1" title="IFITM1">CD225</a></li> <li><a href="/wiki/CD226" title="CD226">CD226</a></li> <li><a href="/wiki/MUC1" class="mw-redirect" title="MUC1">CD227</a></li> <li><a href="/wiki/MFI2" class="mw-redirect" title="MFI2">CD228</a></li> <li><a href="/wiki/LY9" title="LY9">CD229</a></li> <li><a href="/wiki/PRNP" class="mw-redirect" title="PRNP">CD230</a></li> <li><a href="/wiki/Band_3" class="mw-redirect" title="Band 3">CD233</a></li> <li><a href="/wiki/Duffy_antigen_system" title="Duffy antigen system">CD234</a></li> <li><i>CD235</i> <ul><li><a href="/wiki/GYPA" class="mw-redirect" title="GYPA">a</a></li> <li><a href="/wiki/GYPB" title="GYPB">b</a></li></ul></li> <li><a href="/wiki/Glycophorin_C" title="Glycophorin C">CD236</a></li> <li><a href="/wiki/Kell_antigen_system" title="Kell antigen system">CD238</a></li> <li><a href="/wiki/Basal_cell_adhesion_molecule" title="Basal cell adhesion molecule">CD239</a></li> <li><a href="/wiki/RHCE_(gene)" title="RHCE (gene)">CD240CE</a></li> <li><a href="/wiki/RHD_(gene)" title="RHD (gene)">CD240D</a></li> <li><a href="/wiki/RHAG" title="RHAG">CD241</a></li> <li><a href="/wiki/P-glycoprotein" title="P-glycoprotein">CD243</a></li> <li><a href="/wiki/CD244" title="CD244">CD244</a></li> <li><a href="/wiki/Anaplastic_lymphoma_kinase" title="Anaplastic lymphoma kinase">CD246</a></li> <li><a href="/wiki/CD247" class="mw-redirect" title="CD247">CD247</a> - <a href="/wiki/CD248" title="CD248">CD248</a></li> <li><a href="/wiki/Glutamyl_aminopeptidase" title="Glutamyl aminopeptidase">CD249</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">251–300</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/OX40L" class="mw-redirect" title="OX40L"> CD252</a></li> <li><a href="/wiki/TRAIL" title="TRAIL">CD253</a></li> <li><a href="/wiki/RANKL" title="RANKL">CD254</a></li> <li><a href="/wiki/TNFSF13" class="mw-redirect" title="TNFSF13">CD256</a></li> <li><a href="/wiki/B-cell_activating_factor" title="B-cell activating factor">CD257</a></li> <li><a href="/wiki/TNFSF14" class="mw-redirect" title="TNFSF14">CD258</a></li> <li><a href="/wiki/TNFRSF10A" class="mw-redirect" title="TNFRSF10A">CD261</a></li> <li><a href="/wiki/TNFRSF10B" class="mw-redirect" title="TNFRSF10B">CD262</a></li> <li><a href="/wiki/TNFRSF10C" class="mw-redirect" title="TNFRSF10C">CD263</a></li> <li><a href="/wiki/TNFRSF10D" class="mw-redirect" title="TNFRSF10D">CD264</a></li> <li><a href="/wiki/RANK" title="RANK">CD265</a></li> <li><a href="/wiki/TNFRSF12A" title="TNFRSF12A">CD266</a></li> <li><a href="/wiki/TNFRSF13B" class="mw-redirect" title="TNFRSF13B">CD267</a></li> <li><a href="/wiki/TNFRSF13C" class="mw-redirect" title="TNFRSF13C">CD268</a></li> <li><a href="/wiki/TNFRSF17" class="mw-redirect" title="TNFRSF17">CD269</a></li> <li><a href="/wiki/Low-affinity_nerve_growth_factor_receptor" title="Low-affinity nerve growth factor receptor">CD271</a></li> <li><a href="/wiki/BTLA" title="BTLA">CD272</a></li> <li><a href="/wiki/PDCD1LG2" title="PDCD1LG2">CD273</a></li> <li><a href="/wiki/CD274" class="mw-redirect" title="CD274">CD274</a></li> <li><a href="/wiki/ICOSLG" title="ICOSLG">CD275</a></li> <li><a href="/wiki/CD276" title="CD276">CD276</a></li> <li><a href="/wiki/CD278" title="CD278">CD278</a></li> <li><a href="/wiki/Programmed_cell_death_protein_1" title="Programmed cell death protein 1">CD279</a></li> <li><a href="/wiki/Mannose_receptor" title="Mannose receptor">CD280</a></li> <li><a href="/wiki/TLR_1" class="mw-redirect" title="TLR 1">CD281</a></li> <li><a href="/wiki/TLR2" class="mw-redirect" title="TLR2">CD282</a></li> <li><a href="/wiki/TLR3" class="mw-redirect" title="TLR3">CD283</a></li> <li><a href="/wiki/TLR4" class="mw-redirect" title="TLR4">CD284</a></li> <li><a href="/wiki/TLR6" class="mw-redirect" title="TLR6">CD286</a></li> <li><a href="/wiki/TLR8" class="mw-redirect" title="TLR8">CD288</a></li> <li><a href="/wiki/TLR9" class="mw-redirect" title="TLR9">CD289</a></li> <li><a href="/wiki/TLR10" class="mw-redirect" title="TLR10">CD290</a></li> <li><a href="/wiki/BMPR1A" title="BMPR1A">CD292</a></li> <li><a href="/wiki/BMPR1B" title="BMPR1B">CDw293</a></li> <li><a href="/wiki/CD294" class="mw-redirect" title="CD294">CD294</a></li> <li><a href="/wiki/Leptin_receptor" title="Leptin receptor">CD295</a></li> <li><a href="/wiki/ART4" title="ART4">CD297</a></li> <li><a href="/wiki/ATP1B3" title="ATP1B3">CD298</a></li> <li><a href="/wiki/CLEC4M" title="CLEC4M">CD299</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">301–350</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD300A" title="CD300A">CD300A</a></li> <li><a href="/wiki/CLEC10A" title="CLEC10A">CD301</a></li> <li><a href="/wiki/CD302" title="CD302">CD302</a></li> <li><a href="/wiki/CLEC4C" title="CLEC4C">CD303</a></li> <li><a href="/wiki/Neuropilin" title="Neuropilin">CD304</a></li> <li><a href="/wiki/LAIR1" title="LAIR1">CD305</a></li> <li><a href="/wiki/LAIR2" title="LAIR2">CD306</a></li> <li><a href="/wiki/FCRL5" title="FCRL5">CD307</a></li> <li><a href="/wiki/Kinase_insert_domain_receptor" title="Kinase insert domain receptor">CD309</a></li> <li><a href="/wiki/EMR2" title="EMR2">CD312</a></li> <li><a href="/wiki/NKG2D" title="NKG2D">CD314</a></li> <li><a href="/wiki/PTGFRN" title="PTGFRN">CD315</a></li> <li><a href="/wiki/IGSF8" title="IGSF8">CD316</a></li> <li><a href="/wiki/Tetherin" title="Tetherin">CD317</a></li> <li><a href="/wiki/CDCP1" title="CDCP1">CD318</a></li> <li><a href="/wiki/CD320" title="CD320">CD320</a></li> <li><a href="/wiki/F11_receptor" title="F11 receptor">CD321</a></li> <li><a href="/wiki/JAM2" title="JAM2">CD322</a></li> <li><a href="/wiki/CDH1_(gene)" class="mw-redirect" title="CDH1 (gene)">CD324</a></li> <li><a href="/wiki/CDH2" class="mw-redirect" title="CDH2">CD325</a></li> <li><a href="/wiki/Epithelial_cell_adhesion_molecule" title="Epithelial cell adhesion molecule">CD326</a></li> <li><a href="/wiki/SIGLEC6" title="SIGLEC6">CD327</a></li> <li><a href="/wiki/SIGLEC7" title="SIGLEC7">CD328</a></li> <li><a href="/wiki/SIGLEC9" title="SIGLEC9">CD329</a></li> <li><a href="/wiki/Fibroblast_growth_factor_receptor_1" title="Fibroblast growth factor receptor 1">CD331</a></li> <li><a href="/wiki/Fibroblast_growth_factor_receptor_2" title="Fibroblast growth factor receptor 2">CD332</a></li> <li><a href="/wiki/Fibroblast_growth_factor_receptor_3" title="Fibroblast growth factor receptor 3">CD333</a></li> <li><a href="/wiki/Fibroblast_growth_factor_receptor_4" title="Fibroblast growth factor receptor 4">CD334</a></li> <li><a href="/wiki/NCR1" title="NCR1">CD335</a></li> <li><a href="/wiki/NCR2" title="NCR2">CD336</a></li> <li><a href="/wiki/NCR3" title="NCR3">CD337</a></li> <li><a href="/wiki/ABCG2" title="ABCG2">CD338</a></li> <li><a href="/wiki/JAG1" title="JAG1">CD339</a></li> <li><a href="/wiki/HER2/neu" class="mw-redirect" title="HER2/neu">CD340</a></li> <li><a href="/wiki/FZD4" class="mw-redirect" title="FZD4">CD344</a></li> <li><a href="/wiki/FZD9" class="mw-redirect" title="FZD9">CD349</a></li> <li><a href="/wiki/FZD10" class="mw-redirect" title="FZD10">CD350</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="Transmembrane_receptors:_immunoglobulin_superfamily_immune_receptors323" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231" /><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Immunoglobulin_superfamily_immune_receptors" title="Template:Immunoglobulin superfamily immune receptors"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Immunoglobulin_superfamily_immune_receptors" title="Template talk:Immunoglobulin superfamily immune receptors"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Immunoglobulin_superfamily_immune_receptors" title="Special:EditPage/Template:Immunoglobulin superfamily immune receptors"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Transmembrane_receptors:_immunoglobulin_superfamily_immune_receptors323" style="font-size:114%;margin:0 4em"><a href="/wiki/Cell_surface_receptor" title="Cell surface receptor">Transmembrane receptors</a>: <a href="/wiki/Immunoglobulin_superfamily" title="Immunoglobulin superfamily">immunoglobulin superfamily</a> <a href="/wiki/Immune_receptor" title="Immune receptor">immune receptors</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Antibody receptor:<br /><a href="/wiki/Fc_receptor" title="Fc receptor">Fc receptor</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Fc_receptor#Fc-epsilon_receptors" title="Fc receptor">Epsilon (ε)</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Fc%CE%B5RI" class="mw-redirect" title="FcεRI">FcεRI</a></li> <li>(<a href="/wiki/CD23" title="CD23">FcεRII</a> is <a href="/wiki/C-type_lectin" title="C-type lectin">C-type lectin</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Fc_receptor#Fc-gamma_receptors" title="Fc receptor">Gamma (γ)</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD64_(biology)" title="CD64 (biology)">FcγRI</a></li> <li><a href="/wiki/CD32" title="CD32">FcγRII</a></li> <li><a href="/wiki/CD16" title="CD16">FcγRIII</a></li> <li><a href="/wiki/Neonatal_Fc_receptor" class="mw-redirect" title="Neonatal Fc receptor">Neonatal</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Fc_receptor#Fc-alpha_receptors" title="Fc receptor">Alpha (α)/mu (μ)</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/FCAR" title="FCAR">FcαRI</a></li> <li><a href="/wiki/Fc%CE%B1/%CE%BCR" title="Fcα/μR">Fcα/μR</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Secretory</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Polymeric_immunoglobulin_receptor" title="Polymeric immunoglobulin receptor">Polymeric immunoglobulin receptor</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Antigen receptor</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/B_cell" title="B cell">B cells</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Antigen receptor</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/B-cell_receptor" title="B-cell receptor">BCR</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Co-receptor" title="Co-receptor">Co-receptor</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">stimulate:</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Complement_receptor_2" title="Complement receptor 2">CD21</a>/<a href="/wiki/CD19" title="CD19">CD19</a>/<a class="mw-selflink selflink">CD81</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">inhibit:</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD22" title="CD22">CD22</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Accessory molecules</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD79A" title="CD79A">Ig-α</a>/<a href="/wiki/CD79B" title="CD79B">Ig-β</a> (<a href="/wiki/CD79" title="CD79">CD79</a>)</li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/T_cell" title="T cell">T cells</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Ligand" title="Ligand">Ligands</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Major_histocompatibility_complex" title="Major histocompatibility complex">MHC</a> <ul><li><a href="/wiki/MHC_class_I" title="MHC class I">MHC class I</a></li> <li><a href="/wiki/MHC_class_II" title="MHC class II">MHC class II</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Antigen receptor</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/T-cell_receptor" title="T-cell receptor">TCR</a>: <a href="/wiki/TRA@" class="mw-redirect" title="TRA@">TRA@</a></li> <li><a href="/w/index.php?title=TRB@&action=edit&redlink=1" class="new" title="TRB@ (page does not exist)">TRB@</a></li> <li><a href="/wiki/TRD@" class="mw-redirect" title="TRD@">TRD@</a></li> <li><a href="/wiki/TRG@" class="mw-redirect" title="TRG@">TRG@</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Co-receptor" title="Co-receptor">Co-receptors</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD8" title="CD8">CD8</a> (with two glycoprotein chains <a href="/wiki/CD8_alpha" class="mw-redirect" title="CD8 alpha">CD8α</a> and <a href="/wiki/CD8_beta" class="mw-redirect" title="CD8 beta">CD8β</a>)</li> <li><a href="/wiki/CD4" title="CD4">CD4</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Accessory molecules</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD3_(immunology)" title="CD3 (immunology)">CD3</a></li> <li><a href="/wiki/CD3G" title="CD3G">CD3γ</a></li> <li><a href="/wiki/CD3D" title="CD3D">CD3δ</a></li> <li><a href="/wiki/T-cell_surface_glycoprotein_CD3_epsilon_chain" title="T-cell surface glycoprotein CD3 epsilon chain">CD3ε</a></li> <li><a href="/w/index.php?title=Zeta_chain&action=edit&redlink=1" class="new" title="Zeta chain (page does not exist)">ζ-chain</a> (also called <a href="/wiki/CD3_zeta" class="mw-redirect" title="CD3 zeta">CD3ζ</a> and <a href="/w/index.php?title=TCR_zeta&action=edit&redlink=1" class="new" title="TCR zeta (page does not exist)">TCRζ</a>)</li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cytokine_receptor" title="Cytokine receptor">Cytokine receptor</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>see <a href="/wiki/Template:Cytokine_receptors" title="Template:Cytokine receptors">cytokine receptors</a></i></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Killer-cell_immunoglobulin-like_receptor" title="Killer-cell immunoglobulin-like receptor">Killer-cell IG-like receptors</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/KIR2DL1" title="KIR2DL1">KIR2DL1</a></li> <li><a href="/w/index.php?title=KIR2DL2&action=edit&redlink=1" class="new" title="KIR2DL2 (page does not exist)">KIR2DL2</a></li> <li><a href="/wiki/KIR2DL3" class="mw-redirect" title="KIR2DL3">KIR2DL3</a></li> <li><a href="/wiki/KIR2DL4" title="KIR2DL4">KIR2DL4</a></li> <li><a href="/w/index.php?title=KIR2DL5A&action=edit&redlink=1" class="new" title="KIR2DL5A (page does not exist)">KIR2DL5A</a></li> <li><a href="/w/index.php?title=KIR2DL5B&action=edit&redlink=1" class="new" title="KIR2DL5B (page does not exist)">KIR2DL5B</a></li> <li><a href="/wiki/KIR2DS1" title="KIR2DS1">KIR2DS1</a></li> <li><a href="/w/index.php?title=KIR2DS2&action=edit&redlink=1" class="new" title="KIR2DS2 (page does not exist)">KIR2DS2</a></li> <li><a href="/w/index.php?title=KIR2DS3&action=edit&redlink=1" class="new" title="KIR2DS3 (page does not exist)">KIR2DS3</a></li> <li><a href="/wiki/KIR2DS4" title="KIR2DS4">KIR2DS4</a></li> <li><a href="/w/index.php?title=KIR2DS5&action=edit&redlink=1" class="new" title="KIR2DS5 (page does not exist)">KIR2DS5</a></li> <li><a href="/wiki/KIR3DL1" title="KIR3DL1">KIR3DL1</a></li> <li><a href="/wiki/KIR3DL2" title="KIR3DL2">KIR3DL2</a></li> <li><a href="/wiki/KIR3DL3" title="KIR3DL3">KIR3DL3</a></li> <li><a href="/w/index.php?title=KIR3DS1&action=edit&redlink=1" class="new" title="KIR3DS1 (page does not exist)">KIR3DS1</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Leukocyte_immunoglobulin-like_receptors" title="Leukocyte immunoglobulin-like receptors">Leukocyte IG-like receptors</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/LILRA1" title="LILRA1">LILRA1</a></li> <li><a href="/wiki/LILRA2" title="LILRA2">LILRA2</a></li> <li><a href="/wiki/LILRA3" title="LILRA3">LILRA3</a></li> <li><a href="/wiki/LILRA4" title="LILRA4">LILRA4</a></li> <li><a href="/wiki/LILRA5" title="LILRA5">LILRA5</a></li> <li><a href="/w/index.php?title=LILRA6&action=edit&redlink=1" class="new" title="LILRA6 (page does not exist)">LILRA6</a></li> <li><a href="/wiki/LILRB1" title="LILRB1">LILRB1</a></li> <li><a href="/wiki/LILRB2" title="LILRB2">LILRB2</a></li> <li><a href="/wiki/LILRB3" title="LILRB3">LILRB3</a></li> <li><a href="/wiki/LILRB4" title="LILRB4">LILRB4</a></li> <li><a href="/wiki/LILRB5" title="LILRB5">LILRB5</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="Protein:_cell_membrane_proteins_(other_than_Cell_surface_receptor,_enzymes,_and_cytoskeleton)314" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231" /><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Other_cell_membrane_proteins" title="Template:Other cell membrane proteins"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Other_cell_membrane_proteins" title="Template talk:Other cell membrane proteins"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Other_cell_membrane_proteins" title="Special:EditPage/Template:Other cell membrane proteins"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Protein:_cell_membrane_proteins_(other_than_Cell_surface_receptor,_enzymes,_and_cytoskeleton)314" style="font-size:114%;margin:0 4em"><a href="/wiki/Protein" title="Protein">Protein</a>: cell <a href="/wiki/Membrane_protein" title="Membrane protein">membrane proteins</a> (other than <a href="/wiki/Cell_surface_receptor" title="Cell surface receptor">Cell surface receptor</a>, <a href="/wiki/Enzyme" title="Enzyme">enzymes</a>, and <a href="/wiki/Cytoskeleton" title="Cytoskeleton">cytoskeleton</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Arrestin" title="Arrestin">Arrestin</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/SAG_(gene)" title="SAG (gene)">SAG</a></li> <li><a href="/wiki/Arrestin_beta_1" title="Arrestin beta 1">ARRB1</a></li> <li><a href="/wiki/Arrestin_beta_2" title="Arrestin beta 2">ARRB2</a></li> <li><a href="/wiki/ARR3" title="ARR3">ARR3</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Membrane-spanning_4A" title="Membrane-spanning 4A">Membrane-spanning 4A</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD20" title="CD20">MS4A1</a></li> <li><a href="/wiki/MS4A2" title="MS4A2">MS4A2</a></li> <li><a href="/wiki/MS4A3" title="MS4A3">MS4A3</a></li> <li><a href="/w/index.php?title=MS4A4A&action=edit&redlink=1" class="new" title="MS4A4A (page does not exist)">MS4A4A</a></li> <li><a href="/w/index.php?title=MS4A4E&action=edit&redlink=1" class="new" title="MS4A4E (page does not exist)">MS4A4E</a></li> <li><a href="/w/index.php?title=MS4A5&action=edit&redlink=1" class="new" title="MS4A5 (page does not exist)">MS4A5</a></li> <li><a href="/w/index.php?title=MS4A6A&action=edit&redlink=1" class="new" title="MS4A6A (page does not exist)">MS4A6A</a></li> <li><a href="/w/index.php?title=MS4A6E&action=edit&redlink=1" class="new" title="MS4A6E (page does not exist)">MS4A6E</a></li> <li><a href="/wiki/MS4A7" title="MS4A7">MS4A7</a></li> <li><a href="/w/index.php?title=MS4A8B&action=edit&redlink=1" class="new" title="MS4A8B (page does not exist)">MS4A8B</a></li> <li><a href="/w/index.php?title=MS4A9&action=edit&redlink=1" class="new" title="MS4A9 (page does not exist)">MS4A9</a></li> <li><a href="/w/index.php?title=MS4A10&action=edit&redlink=1" class="new" title="MS4A10 (page does not exist)">MS4A10</a></li> <li><a href="/w/index.php?title=MS4A12&action=edit&redlink=1" class="new" title="MS4A12 (page does not exist)">MS4A12</a></li> <li><a href="/w/index.php?title=MS4A13&action=edit&redlink=1" class="new" title="MS4A13 (page does not exist)">MS4A13</a></li> <li><a href="/w/index.php?title=MS4A14&action=edit&redlink=1" class="new" title="MS4A14 (page does not exist)">MS4A14</a></li> <li><a href="/w/index.php?title=MS4A15&action=edit&redlink=1" class="new" title="MS4A15 (page does not exist)">MS4A15</a></li> <li><a href="/w/index.php?title=MS4A18&action=edit&redlink=1" class="new" title="MS4A18 (page does not exist)">MS4A18</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Myelin" title="Myelin">Myelin</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Myelin_basic_protein" title="Myelin basic protein">Myelin basic protein</a> <ul><li><a href="/wiki/PMP2" title="PMP2">PMP2</a></li></ul></li> <li><a href="/wiki/Myelin_proteolipid_protein" title="Myelin proteolipid protein">Myelin proteolipid protein</a> <ul><li><a href="/wiki/Proteolipid_protein_1" title="Proteolipid protein 1">PLP1</a></li></ul></li> <li><a href="/wiki/Myelin_oligodendrocyte_glycoprotein" title="Myelin oligodendrocyte glycoprotein">Myelin oligodendrocyte glycoprotein</a></li> <li><a href="/wiki/Myelin-associated_glycoprotein" title="Myelin-associated glycoprotein">Myelin-associated glycoprotein</a></li> <li><a href="/wiki/Myelin_protein_zero" title="Myelin protein zero">Myelin protein zero</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Pulmonary_surfactant" title="Pulmonary surfactant">Pulmonary surfactant</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Surfactant_protein_B" title="Surfactant protein B">Pulmonary surfactant-associated protein B</a></li> <li><a href="/wiki/Surfactant_protein_C" title="Surfactant protein C">Pulmonary surfactant-associated protein C</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Tetraspanin" title="Tetraspanin">Tetraspanin</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=TSPAN1&action=edit&redlink=1" class="new" title="TSPAN1 (page does not exist)">TSPAN1</a></li> <li><a href="/wiki/TSPAN2" title="TSPAN2">TSPAN2</a></li> <li><a href="/wiki/TSPAN3" title="TSPAN3">TSPAN3</a></li> <li><a href="/wiki/TSPAN4" title="TSPAN4">TSPAN4</a></li> <li><a href="/w/index.php?title=TSPAN5&action=edit&redlink=1" class="new" title="TSPAN5 (page does not exist)">TSPAN5</a></li> <li><a href="/wiki/TSPAN6" title="TSPAN6">TSPAN6</a></li> <li><a href="/wiki/TSPAN7" title="TSPAN7">TSPAN7</a></li> <li><a href="/wiki/TSPAN8" title="TSPAN8">TSPAN8</a></li> <li><a href="/wiki/TSPAN9" class="mw-redirect" title="TSPAN9">TSPAN9</a></li> <li><a href="/wiki/TSPAN10" class="mw-redirect" title="TSPAN10">TSPAN10</a></li> <li><a href="/w/index.php?title=TSPAN11&action=edit&redlink=1" class="new" title="TSPAN11 (page does not exist)">TSPAN11</a></li> <li><a href="/wiki/TSPAN12" title="TSPAN12">TSPAN12</a></li> <li><a href="/wiki/TSPAN13" title="TSPAN13">TSPAN13</a></li> <li><a href="/wiki/TSPAN14" title="TSPAN14">TSPAN14</a></li> <li><a href="/w/index.php?title=TSPAN15&action=edit&redlink=1" class="new" title="TSPAN15 (page does not exist)">TSPAN15</a></li> <li><a href="/w/index.php?title=TSPAN16&action=edit&redlink=1" class="new" title="TSPAN16 (page does not exist)">TSPAN16</a></li> <li><a href="/w/index.php?title=TSPAN17&action=edit&redlink=1" class="new" title="TSPAN17 (page does not exist)">TSPAN17</a></li> <li><a href="/wiki/TSPAN18" class="mw-redirect" title="TSPAN18">TSPAN18</a></li> <li><a href="/w/index.php?title=TSPAN19&action=edit&redlink=1" class="new" title="TSPAN19 (page does not exist)">TSPAN19</a></li> <li><a href="/w/index.php?title=TSPAN20&action=edit&redlink=1" class="new" title="TSPAN20 (page does not exist)">TSPAN20</a></li> <li><a href="/wiki/TSPAN21" class="mw-redirect" title="TSPAN21">TSPAN21</a></li> <li><a href="/w/index.php?title=TSPAN22&action=edit&redlink=1" class="new" title="TSPAN22 (page does not exist)">TSPAN22</a></li> <li><a href="/wiki/TSPAN23" class="mw-redirect" title="TSPAN23">TSPAN23</a></li> <li><a href="/wiki/CD151" title="CD151">TSPAN24</a></li> <li><a href="/wiki/CD53" title="CD53">TSPAN25</a></li> <li><a href="/wiki/CD37" title="CD37">TSPAN26</a></li> <li><a href="/wiki/CD82_(gene)" title="CD82 (gene)">TSPAN27</a></li> <li><a class="mw-selflink selflink">TSPAN28</a></li> <li><a href="/wiki/CD9" title="CD9">TSPAN29</a></li> <li><a href="/wiki/CD63" title="CD63">TSPAN30</a></li> <li><a href="/wiki/TSPAN31" title="TSPAN31">TSPAN31</a></li> <li><a href="/wiki/TSPAN32" title="TSPAN32">TSPAN32</a></li> <li><a href="/w/index.php?title=TSPAN33&action=edit&redlink=1" class="new" title="TSPAN33 (page does not exist)">TSPAN33</a></li> <li><a href="/w/index.php?title=TSPAN34&action=edit&redlink=1" class="new" title="TSPAN34 (page does not exist)">TSPAN34</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other/ungrouped</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Calnexin" title="Calnexin">Calnexin</a></li> <li><a href="/wiki/LDL-receptor-related_protein-associated_protein" title="LDL-receptor-related protein-associated protein">LDL-receptor-related protein-associated protein</a></li> <li><a href="/wiki/Merlin_(protein)" title="Merlin (protein)">Neurofibromin 2</a></li> <li><a href="/wiki/Presenilin" title="Presenilin">Presenilin</a> <ul><li><a href="/wiki/Presenilin-1" title="Presenilin-1">PSEN1</a></li> <li><a href="/wiki/Presenilin-2" title="Presenilin-2">PSEN2</a></li></ul></li> <li><a href="/wiki/HFE_(gene)" title="HFE (gene)">HFE</a></li> <li><a href="/wiki/Phospholipid_scramblase" title="Phospholipid scramblase">Phospholipid transfer proteins</a></li> <li><a href="/wiki/Dysferlin" title="Dysferlin">Dysferlin</a></li> <li><a href="/wiki/STRC" title="STRC">STRC</a></li> <li><a href="/wiki/Otoferlin" title="Otoferlin">OTOF</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="padding:0;"><div><i>see also <a href="/wiki/Template:Other_cell_membrane_protein_disorders" title="Template:Other cell membrane protein disorders">other cell membrane protein disorders</a></i></div></td></tr></tbody></table></div> <p><i>This article incorporates text from the <a href="/wiki/United_States_National_Library_of_Medicine" title="United States National Library of Medicine">United States National Library of Medicine</a>, which is in the <a href="/wiki/Public_domain" title="Public domain">public domain</a>.</i> </p> <!-- NewPP limit report Parsed by mw‐web.eqiad.main‐648967dbcc‐nqgn7 Cached time: 20250306000105 Cache expiry: 2592000 Reduced expiry: false Complications: [vary‐revision‐sha1, show‐toc] CPU time usage: 0.975 seconds Real time usage: 1.644 seconds Preprocessor visited node count: 2981/1000000 Post‐expand include size: 253263/2097152 bytes Template argument size: 602/2097152 bytes Highest expansion depth: 10/100 Expensive parser function count: 46/500 Unstrip recursion depth: 1/20 Unstrip post‐expand size: 186899/5000000 bytes Lua time usage: 0.696/10.000 seconds Lua memory usage: 9660169/52428800 bytes Number of Wikibase entities loaded: 46/400 --> <!-- Transclusion expansion time report (%,ms,calls,template) 100.00% 1171.088 1 -total 55.16% 645.938 1 Template:Infobox_gene 19.25% 225.468 42 Template:Cite_journal 13.63% 159.596 1 Template:Reflist 11.58% 135.566 9 Template:Navbox 8.82% 103.321 1 Template:PDB_Gallery 8.27% 96.904 1 Template:Short_description 4.84% 56.648 2 Template:Pagetype 2.31% 27.075 3 Template:Main_other 2.13% 24.955 1 Template:SDcat --> <!-- Saved in parser cache with key enwiki:pcache:14722590:|#|:idhash:canonical and timestamp 20250306000105 and revision id 1251266020. Rendering was triggered because: page-view --> </div><!--esi <esi:include src="/esitest-fa8a495983347898/content" /> --><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?useformat=desktop&type=1x1&usesul3=0" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Retrieved from "<a dir="ltr" href="https://en.wikipedia.org/w/index.php?title=CD81&oldid=1251266020">https://en.wikipedia.org/w/index.php?title=CD81&oldid=1251266020</a>"</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Help:Category" title="Help:Category">Categories</a>: <ul><li><a href="/wiki/Category:Genes_on_human_chromosome_11" title="Category:Genes on human chromosome 11">Genes on human chromosome 11</a></li><li><a href="/wiki/Category:Clusters_of_differentiation" title="Category:Clusters of differentiation">Clusters of differentiation</a></li></ul></div><div id="mw-hidden-catlinks" class="mw-hidden-catlinks mw-hidden-cats-hidden">Hidden categories: <ul><li><a href="/wiki/Category:Articles_with_short_description" title="Category:Articles with short description">Articles with short description</a></li><li><a href="/wiki/Category:Short_description_is_different_from_Wikidata" title="Category:Short description is different from Wikidata">Short description is different from Wikidata</a></li><li><a href="/wiki/Category:Wikipedia_articles_incorporating_text_from_the_United_States_National_Library_of_Medicine" title="Category:Wikipedia articles incorporating text from the United States National Library of Medicine">Wikipedia articles incorporating text from the United States National Library of Medicine</a></li></ul></div></div> </div> </main> </div> <div class="mw-footer-container"> <footer id="footer" class="mw-footer" > <ul id="footer-info"> <li id="footer-info-lastmod"> This page was last edited on 15 October 2024, at 07:20<span class="anonymous-show"> (UTC)</span>.</li> <li id="footer-info-copyright">Text is available under the <a href="/wiki/Wikipedia:Text_of_the_Creative_Commons_Attribution-ShareAlike_4.0_International_License" title="Wikipedia:Text of the Creative Commons Attribution-ShareAlike 4.0 International License">Creative Commons Attribution-ShareAlike 4.0 License</a>; additional terms may apply. By using this site, you agree to the <a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Terms_of_Use" class="extiw" title="foundation:Special:MyLanguage/Policy:Terms of Use">Terms of Use</a> and <a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Privacy_policy" class="extiw" title="foundation:Special:MyLanguage/Policy:Privacy policy">Privacy Policy</a>. Wikipedia® is a registered trademark of the <a rel="nofollow" class="external text" href="https://wikimediafoundation.org/">Wikimedia Foundation, Inc.</a>, a non-profit organization.</li> </ul> <ul id="footer-places"> <li id="footer-places-privacy"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Privacy_policy">Privacy policy</a></li> <li id="footer-places-about"><a href="/wiki/Wikipedia:About">About Wikipedia</a></li> <li id="footer-places-disclaimers"><a href="/wiki/Wikipedia:General_disclaimer">Disclaimers</a></li> <li id="footer-places-contact"><a href="//en.wikipedia.org/wiki/Wikipedia:Contact_us">Contact Wikipedia</a></li> <li id="footer-places-wm-codeofconduct"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Universal_Code_of_Conduct">Code of Conduct</a></li> <li id="footer-places-developers"><a href="https://developer.wikimedia.org">Developers</a></li> <li id="footer-places-statslink"><a href="https://stats.wikimedia.org/#/en.wikipedia.org">Statistics</a></li> <li id="footer-places-cookiestatement"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Cookie_statement">Cookie statement</a></li> <li id="footer-places-mobileview"><a href="//en.m.wikipedia.org/w/index.php?title=CD81&mobileaction=toggle_view_mobile" class="noprint stopMobileRedirectToggle">Mobile view</a></li> </ul> <ul id="footer-icons" class="noprint"> <li id="footer-copyrightico"><a href="https://wikimediafoundation.org/" class="cdx-button cdx-button--fake-button cdx-button--size-large cdx-button--fake-button--enabled"><picture><source media="(min-width: 500px)" srcset="/static/images/footer/wikimedia-button.svg" width="84" height="29"><img src="/static/images/footer/wikimedia.svg" width="25" height="25" alt="Wikimedia Foundation" lang="en" loading="lazy"></picture></a></li> <li id="footer-poweredbyico"><a href="https://www.mediawiki.org/" class="cdx-button cdx-button--fake-button cdx-button--size-large cdx-button--fake-button--enabled"><picture><source media="(min-width: 500px)" srcset="/w/resources/assets/poweredby_mediawiki.svg" width="88" height="31"><img src="/w/resources/assets/mediawiki_compact.svg" alt="Powered by MediaWiki" lang="en" width="25" height="25" loading="lazy"></picture></a></li> </ul> </footer> </div> </div> </div> <div class="vector-header-container vector-sticky-header-container"> <div id="vector-sticky-header" class="vector-sticky-header"> <div class="vector-sticky-header-start"> <div class="vector-sticky-header-icon-start vector-button-flush-left vector-button-flush-right" aria-hidden="true"> <button class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-sticky-header-search-toggle" tabindex="-1" data-event-name="ui.vector-sticky-search-form.icon"><span class="vector-icon mw-ui-icon-search mw-ui-icon-wikimedia-search"></span> <span>Search</span> </button> </div> <div role="search" class="vector-search-box-vue vector-search-box-show-thumbnail vector-search-box"> <div class="vector-typeahead-search-container"> <div class="cdx-typeahead-search cdx-typeahead-search--show-thumbnail"> <form action="/w/index.php" id="vector-sticky-search-form" class="cdx-search-input cdx-search-input--has-end-button"> <div class="cdx-search-input__input-wrapper" data-search-loc="header-moved"> <div class="cdx-text-input cdx-text-input--has-start-icon"> <input class="cdx-text-input__input" type="search" name="search" placeholder="Search Wikipedia"> <span class="cdx-text-input__icon cdx-text-input__start-icon"></span> </div> <input type="hidden" name="title" value="Special:Search"> </div> <button class="cdx-button cdx-search-input__end-button">Search</button> </form> </div> </div> </div> <div class="vector-sticky-header-context-bar"> <nav aria-label="Contents" class="vector-toc-landmark"> <div id="vector-sticky-header-toc" class="vector-dropdown mw-portlet mw-portlet-sticky-header-toc vector-sticky-header-toc vector-button-flush-left" > <input type="checkbox" id="vector-sticky-header-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-sticky-header-toc" class="vector-dropdown-checkbox " aria-label="Toggle the table of contents" > <label id="vector-sticky-header-toc-label" for="vector-sticky-header-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Toggle the table of contents</span> </label> <div class="vector-dropdown-content"> <div id="vector-sticky-header-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <div class="vector-sticky-header-context-bar-primary" aria-hidden="true" ><span class="mw-page-title-main">CD81</span></div> </div> </div> <div class="vector-sticky-header-end" aria-hidden="true"> <div class="vector-sticky-header-icons"> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-talk-sticky-header" tabindex="-1" data-event-name="talk-sticky-header"><span class="vector-icon mw-ui-icon-speechBubbles mw-ui-icon-wikimedia-speechBubbles"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-subject-sticky-header" tabindex="-1" data-event-name="subject-sticky-header"><span class="vector-icon mw-ui-icon-article mw-ui-icon-wikimedia-article"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-history-sticky-header" tabindex="-1" data-event-name="history-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-history mw-ui-icon-wikimedia-wikimedia-history"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only mw-watchlink" id="ca-watchstar-sticky-header" tabindex="-1" data-event-name="watch-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-star mw-ui-icon-wikimedia-wikimedia-star"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-edit-sticky-header" tabindex="-1" data-event-name="wikitext-edit-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-wikiText mw-ui-icon-wikimedia-wikimedia-wikiText"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-ve-edit-sticky-header" tabindex="-1" data-event-name="ve-edit-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-edit mw-ui-icon-wikimedia-wikimedia-edit"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-viewsource-sticky-header" tabindex="-1" data-event-name="ve-edit-protected-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-editLock mw-ui-icon-wikimedia-wikimedia-editLock"></span> <span></span> </a> </div> <div class="vector-sticky-header-buttons"> <button class="cdx-button cdx-button--weight-quiet mw-interlanguage-selector" id="p-lang-btn-sticky-header" tabindex="-1" data-event-name="ui.dropdown-p-lang-btn-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-language mw-ui-icon-wikimedia-wikimedia-language"></span> <span>9 languages</span> </button> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive" id="ca-addsection-sticky-header" tabindex="-1" data-event-name="addsection-sticky-header"><span class="vector-icon mw-ui-icon-speechBubbleAdd-progressive mw-ui-icon-wikimedia-speechBubbleAdd-progressive"></span> <span>Add topic</span> </a> </div> <div class="vector-sticky-header-icon-end"> <div class="vector-user-links"> </div> </div> </div> </div> </div> <div class="mw-portlet mw-portlet-dock-bottom emptyPortlet" id="p-dock-bottom"> <ul> </ul> </div> <script>(RLQ=window.RLQ||[]).push(function(){mw.config.set({"wgHostname":"mw-web.codfw.main-7dbfd665b5-f7wc4","wgBackendResponseTime":188,"wgPageParseReport":{"limitreport":{"cputime":"0.975","walltime":"1.644","ppvisitednodes":{"value":2981,"limit":1000000},"postexpandincludesize":{"value":253263,"limit":2097152},"templateargumentsize":{"value":602,"limit":2097152},"expansiondepth":{"value":10,"limit":100},"expensivefunctioncount":{"value":46,"limit":500},"unstrip-depth":{"value":1,"limit":20},"unstrip-size":{"value":186899,"limit":5000000},"entityaccesscount":{"value":46,"limit":400},"timingprofile":["100.00% 1171.088 1 -total"," 55.16% 645.938 1 Template:Infobox_gene"," 19.25% 225.468 42 Template:Cite_journal"," 13.63% 159.596 1 Template:Reflist"," 11.58% 135.566 9 Template:Navbox"," 8.82% 103.321 1 Template:PDB_Gallery"," 8.27% 96.904 1 Template:Short_description"," 4.84% 56.648 2 Template:Pagetype"," 2.31% 27.075 3 Template:Main_other"," 2.13% 24.955 1 Template:SDcat"]},"scribunto":{"limitreport-timeusage":{"value":"0.696","limit":"10.000"},"limitreport-memusage":{"value":9660169,"limit":52428800}},"cachereport":{"origin":"mw-web.eqiad.main-648967dbcc-nqgn7","timestamp":"20250306000105","ttl":2592000,"transientcontent":false}}});});</script> <script type="application/ld+json">{"@context":"https:\/\/schema.org","@type":"Article","name":"CD81","url":"https:\/\/en.wikipedia.org\/wiki\/CD81","sameAs":"http:\/\/www.wikidata.org\/entity\/Q21131199","mainEntity":"http:\/\/www.wikidata.org\/entity\/Q21131199","author":{"@type":"Organization","name":"Contributors to Wikimedia projects"},"publisher":{"@type":"Organization","name":"Wikimedia Foundation, Inc.","logo":{"@type":"ImageObject","url":"https:\/\/www.wikimedia.org\/static\/images\/wmf-hor-googpub.png"}},"datePublished":"2007-12-15T22:11:00Z","dateModified":"2024-10-15T07:20:17Z","image":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/2\/26\/Protein_CD81_PDB_1g8q.png","headline":"mammalian protein found in Homo sapiens"}</script> </body> </html>