Klinische Forschung, Arzneimittel-Entwicklung und Zulassung

<!doctype html> <html lang="de-DE"> <head> <meta charset="UTF-8"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1"> <link rel="profile" href="https://gmpg.org/xfn/11"> <link rel="preload" as="font" type="font/woff2" href="/wp-content/themes/mhh-mhh2-mcc-theme/fonts/InventionVF_W_Wght.woff2" crossorigin="anonymous"> <link rel="preload" as="font" type="font/woff2" href="/wp-content/themes/mhh-mhh2-mcc-theme/fonts/InventionVF_Italics_W_Wght.woff2" crossorigin="anonymous"> <meta name='robots' content='index, follow, max-image-preview:large, max-snippet:-1, max-video-preview:-1' />  <title>Klinische Forschung, Arzneimittel-Entwicklung und Zulassung | MSD</title> <meta name="description" content="Erfahren Sie mehr über die klinische Forschung von MSD, die Entwicklung und die sorgfältige Prüfung vor der Zulassung neuer Medikamente" /> <link rel="canonical" href="https://www.msd.de/forschung-und-arzneimittel/hintergrundwissen/" /> <meta property="og:locale" content="en_US" /> <meta property="og:type" content="article" /> <meta property="og:title" content="Klinische Studien und klinische Forschung bei MSD" /> <meta property="og:description" content="Die Klinische Forschung von MSD entwickelt Arzneimittel. Der Zulassung jedes neuen Medikaments geht eine sorgfältige Prüfung voraus. In klinischen Studien werden die Sicherheit und Wirksamkeit einer Substanz geprüft, Nebenwirkungen und die Wechselwirkungen mit anderen Medikamenten überwacht." /> <meta property="og:url" content="https://www.msd.de/forschung-und-arzneimittel/hintergrundwissen/" /> <meta property="og:site_name" content="msd.de" /> <meta property="article:modified_time" content="2023-11-24T10:01:02+00:00" /> <meta property="og:image" content="https://www.msd.de/wp-content/uploads/sites/33/2021/10/17425285_Labor-2048x1365px.jpg?w=1024" /> <meta property="og:image:width" content="1024" /> <meta property="og:image:height" content="683" /> <meta property="og:image:type" content="image/jpeg" /> <meta name="twitter:card" content="summary_large_image" /> <meta name="twitter:title" content="Klinische Studien und klinische Forschung bei MSD" /> <meta name="twitter:description" content="Die Klinische Forschung von MSD entwickelt Arzneimittel. Der Zulassung jedes neuen Medikaments geht eine sorgfältige Prüfung voraus. In klinischen Studien werden die Sicherheit und Wirksamkeit einer Substanz geprüft, Nebenwirkungen und die Wechselwirkungen mit anderen Medikamenten überwacht." /> <meta name="twitter:image" content="https://www.msd.de/wp-content/uploads/sites/33/2021/10/17425285_Labor-2048x1365px.jpg" /> <meta name="twitter:site" content="@msd_deutschland" /> <meta name="twitter:label1" content="Est. reading time" /> <meta name="twitter:data1" content="6 minutes" /> <script type="application/ld+json" class="yoast-schema-graph">{"@context":"https://schema.org","@graph":[{"@type":"WebPage","@id":"https://www.msd.de/forschung-und-arzneimittel/hintergrundwissen/","url":"https://www.msd.de/forschung-und-arzneimittel/hintergrundwissen/","name":"Klinische Forschung, Arzneimittel-Entwicklung und Zulassung | MSD","isPartOf":{"@id":"https://www.msd.de/#website"},"primaryImageOfPage":{"@id":"https://www.msd.de/forschung-und-arzneimittel/hintergrundwissen/#primaryimage"},"image":{"@id":"https://www.msd.de/forschung-und-arzneimittel/hintergrundwissen/#primaryimage"},"thumbnailUrl":"https://www.msd.de/wp-content/uploads/sites/33/2021/10/family2.png?w=313","datePublished":"2020-11-08T22:53:08+00:00","dateModified":"2023-11-24T10:01:02+00:00","description":"Erfahren Sie mehr über die klinische Forschung von MSD, die Entwicklung und die sorgfältige Prüfung vor der Zulassung neuer Medikamente","breadcrumb":{"@id":"https://www.msd.de/forschung-und-arzneimittel/hintergrundwissen/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https://www.msd.de/forschung-und-arzneimittel/hintergrundwissen/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https://www.msd.de/forschung-und-arzneimittel/hintergrundwissen/#primaryimage","url":"https://www.msd.de/wp-content/uploads/sites/33/2021/10/family2.png","contentUrl":"https://www.msd.de/wp-content/uploads/sites/33/2021/10/family2.png","width":313,"height":286,"caption":"Icon"},{"@type":"BreadcrumbList","@id":"https://www.msd.de/forschung-und-arzneimittel/hintergrundwissen/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Forschung und Arzneimittel","item":"https://www.msd.de/forschung-und-arzneimittel/"},{"@type":"ListItem","position":2,"name":"Hintergrundwissen"}]},{"@type":"WebSite","@id":"https://www.msd.de/#website","url":"https://www.msd.de/","name":"msd.de","description":"Corporate Website von MSD Deutschland","publisher":{"@id":"https://www.msd.de/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https://www.msd.de/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https://www.msd.de/#organization","name":"MSD SHARP & DOHME GMBH","url":"https://www.msd.de/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https://www.msd.de/#/schema/logo/image/","url":"https://www.msd.de/wp-content/uploads/sites/33/2020/11/MSD.png","contentUrl":"https://www.msd.de/wp-content/uploads/sites/33/2020/11/MSD.png","width":2536,"height":1382,"caption":"MSD SHARP & DOHME GMBH"},"image":{"@id":"https://www.msd.de/#/schema/logo/image/"},"sameAs":["https://twitter.com/msd_deutschland","https://de.linkedin.com/company/msd-deutschland","https://www.youtube.com/user/MsdDeutschland","https://de.wikipedia.org/wiki/Merck_&_Co."]}]}</script>  <link rel='dns-prefetch' href='//cdn.cookielaw.org' /> <link rel='stylesheet' id='wp-block-library-css' href='https://www.msd.de/wp-includes/css/dist/block-library/style.min.css?ver=6.2.6' media='all' /> <style id='wp-block-library-inline-css'> .has-text-align-justify{text-align:justify;} </style> <link rel='stylesheet' id='mediaelement-css' href='https://www.msd.de/wp-includes/js/mediaelement/mediaelementplayer-legacy.min.css?ver=4.2.17' media='all' /> <link rel='stylesheet' id='wp-mediaelement-css' href='https://www.msd.de/wp-includes/js/mediaelement/wp-mediaelement.min.css?ver=6.2.6' media='all' /> <style id='elasticpress-facet-style-inline-css'> .widget_ep-facet input[type=search],.wp-block-elasticpress-facet input[type=search]{margin-bottom:1rem}.widget_ep-facet .searchable .inner,.wp-block-elasticpress-facet .searchable .inner{max-height:20em;overflow:scroll}.widget_ep-facet .term.hide,.wp-block-elasticpress-facet .term.hide{display:none}.widget_ep-facet .empty-term,.wp-block-elasticpress-facet .empty-term{opacity:.5;position:relative}.widget_ep-facet .empty-term:after,.wp-block-elasticpress-facet .empty-term:after{bottom:0;content:" ";display:block;left:0;position:absolute;right:0;top:0;width:100%;z-index:2}.widget_ep-facet .level-1,.wp-block-elasticpress-facet .level-1{padding-left:20px}.widget_ep-facet .level-2,.wp-block-elasticpress-facet .level-2{padding-left:40px}.widget_ep-facet .level-3,.wp-block-elasticpress-facet .level-3{padding-left:60px}.widget_ep-facet .level-4,.wp-block-elasticpress-facet .level-4{padding-left:5pc}.widget_ep-facet .level-5,.wp-block-elasticpress-facet .level-5{padding-left:75pt}.widget_ep-facet input[disabled],.wp-block-elasticpress-facet input[disabled]{cursor:pointer;opacity:1}.widget_ep-facet .term a,.wp-block-elasticpress-facet .term a{-webkit-box-align:center;-ms-flex-align:center;align-items:center;display:-webkit-box;display:-ms-flexbox;display:flex;position:relative}.widget_ep-facet .term a:hover .ep-checkbox,.wp-block-elasticpress-facet .term a:hover .ep-checkbox{background-color:#ccc}.ep-checkbox{-webkit-box-align:center;-ms-flex-align:center;-ms-flex-negative:0;-webkit-box-pack:center;-ms-flex-pack:center;align-items:center;background-color:#eee;display:-webkit-box;display:-ms-flexbox;display:flex;flex-shrink:0;height:1em;justify-content:center;margin-right:.25em;width:1em}.ep-checkbox:after{border:solid #fff;border-width:0 .125em .125em 0;content:"";display:none;height:.5em;-webkit-transform:rotate(45deg);transform:rotate(45deg);width:.25em}.ep-checkbox.checked{background-color:#5e5e5e}.ep-checkbox.checked:after{display:block} </style> <link rel='stylesheet' id='elasticpress-related-posts-block-css' href='https://www.msd.de/wp-content/mu-plugins/search/elasticpress/dist/css/related-posts-block-styles.min.css?ver=4.2.2' media='all' /> <link rel='stylesheet' id='classic-theme-styles-css' href='https://www.msd.de/wp-includes/css/classic-themes.min.css?ver=6.2.6' media='all' /> <style id='global-styles-inline-css'> body{--wp--preset--color--black: #000000;--wp--preset--color--cyan-bluish-gray: #abb8c3;--wp--preset--color--white: #ffffff;--wp--preset--color--pale-pink: #f78da7;--wp--preset--color--vivid-red: #cf2e2e;--wp--preset--color--luminous-vivid-orange: #ff6900;--wp--preset--color--luminous-vivid-amber: #fcb900;--wp--preset--color--light-green-cyan: #7bdcb5;--wp--preset--color--vivid-green-cyan: #00d084;--wp--preset--color--pale-cyan-blue: #8ed1fc;--wp--preset--color--vivid-cyan-blue: #0693e3;--wp--preset--color--vivid-purple: #9b51e0;--wp--preset--gradient--vivid-cyan-blue-to-vivid-purple: linear-gradient(135deg,rgba(6,147,227,1) 0%,rgb(155,81,224) 100%);--wp--preset--gradient--light-green-cyan-to-vivid-green-cyan: linear-gradient(135deg,rgb(122,220,180) 0%,rgb(0,208,130) 100%);--wp--preset--gradient--luminous-vivid-amber-to-luminous-vivid-orange: linear-gradient(135deg,rgba(252,185,0,1) 0%,rgba(255,105,0,1) 100%);--wp--preset--gradient--luminous-vivid-orange-to-vivid-red: linear-gradient(135deg,rgba(255,105,0,1) 0%,rgb(207,46,46) 100%);--wp--preset--gradient--very-light-gray-to-cyan-bluish-gray: linear-gradient(135deg,rgb(238,238,238) 0%,rgb(169,184,195) 100%);--wp--preset--gradient--cool-to-warm-spectrum: linear-gradient(135deg,rgb(74,234,220) 0%,rgb(151,120,209) 20%,rgb(207,42,186) 40%,rgb(238,44,130) 60%,rgb(251,105,98) 80%,rgb(254,248,76) 100%);--wp--preset--gradient--blush-light-purple: linear-gradient(135deg,rgb(255,206,236) 0%,rgb(152,150,240) 100%);--wp--preset--gradient--blush-bordeaux: linear-gradient(135deg,rgb(254,205,165) 0%,rgb(254,45,45) 50%,rgb(107,0,62) 100%);--wp--preset--gradient--luminous-dusk: linear-gradient(135deg,rgb(255,203,112) 0%,rgb(199,81,192) 50%,rgb(65,88,208) 100%);--wp--preset--gradient--pale-ocean: linear-gradient(135deg,rgb(255,245,203) 0%,rgb(182,227,212) 50%,rgb(51,167,181) 100%);--wp--preset--gradient--electric-grass: linear-gradient(135deg,rgb(202,248,128) 0%,rgb(113,206,126) 100%);--wp--preset--gradient--midnight: linear-gradient(135deg,rgb(2,3,129) 0%,rgb(40,116,252) 100%);--wp--preset--duotone--dark-grayscale: url('#wp-duotone-dark-grayscale');--wp--preset--duotone--grayscale: url('#wp-duotone-grayscale');--wp--preset--duotone--purple-yellow: url('#wp-duotone-purple-yellow');--wp--preset--duotone--blue-red: url('#wp-duotone-blue-red');--wp--preset--duotone--midnight: url('#wp-duotone-midnight');--wp--preset--duotone--magenta-yellow: url('#wp-duotone-magenta-yellow');--wp--preset--duotone--purple-green: url('#wp-duotone-purple-green');--wp--preset--duotone--blue-orange: url('#wp-duotone-blue-orange');--wp--preset--font-size--small: 13px;--wp--preset--font-size--medium: 20px;--wp--preset--font-size--large: 36px;--wp--preset--font-size--x-large: 42px;--wp--preset--spacing--20: 0.44rem;--wp--preset--spacing--30: 0.67rem;--wp--preset--spacing--40: 1rem;--wp--preset--spacing--50: 1.5rem;--wp--preset--spacing--60: 2.25rem;--wp--preset--spacing--70: 3.38rem;--wp--preset--spacing--80: 5.06rem;--wp--preset--shadow--natural: 6px 6px 9px rgba(0, 0, 0, 0.2);--wp--preset--shadow--deep: 12px 12px 50px rgba(0, 0, 0, 0.4);--wp--preset--shadow--sharp: 6px 6px 0px rgba(0, 0, 0, 0.2);--wp--preset--shadow--outlined: 6px 6px 0px -3px rgba(255, 255, 255, 1), 6px 6px rgba(0, 0, 0, 1);--wp--preset--shadow--crisp: 6px 6px 0px rgba(0, 0, 0, 1);}:where(.is-layout-flex){gap: 0.5em;}body .is-layout-flow > .alignleft{float: left;margin-inline-start: 0;margin-inline-end: 2em;}body .is-layout-flow > .alignright{float: right;margin-inline-start: 2em;margin-inline-end: 0;}body .is-layout-flow > .aligncenter{margin-left: auto !important;margin-right: auto !important;}body .is-layout-constrained > .alignleft{float: left;margin-inline-start: 0;margin-inline-end: 2em;}body .is-layout-constrained > .alignright{float: right;margin-inline-start: 2em;margin-inline-end: 0;}body .is-layout-constrained > .aligncenter{margin-left: auto !important;margin-right: auto !important;}body .is-layout-constrained > :where(:not(.alignleft):not(.alignright):not(.alignfull)){max-width: var(--wp--style--global--content-size);margin-left: auto !important;margin-right: auto !important;}body .is-layout-constrained > .alignwide{max-width: var(--wp--style--global--wide-size);}body .is-layout-flex{display: flex;}body .is-layout-flex{flex-wrap: wrap;align-items: center;}body .is-layout-flex > *{margin: 0;}:where(.wp-block-columns.is-layout-flex){gap: 2em;}.has-black-color{color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-color{color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-color{color: var(--wp--preset--color--white) !important;}.has-pale-pink-color{color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-color{color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-color{color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-color{color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-color{color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-color{color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-color{color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-color{color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-color{color: var(--wp--preset--color--vivid-purple) !important;}.has-black-background-color{background-color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-background-color{background-color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-background-color{background-color: var(--wp--preset--color--white) !important;}.has-pale-pink-background-color{background-color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-background-color{background-color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-background-color{background-color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-background-color{background-color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-background-color{background-color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-background-color{background-color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-background-color{background-color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-background-color{background-color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-background-color{background-color: var(--wp--preset--color--vivid-purple) !important;}.has-black-border-color{border-color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-border-color{border-color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-border-color{border-color: var(--wp--preset--color--white) !important;}.has-pale-pink-border-color{border-color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-border-color{border-color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-border-color{border-color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-border-color{border-color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-border-color{border-color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-border-color{border-color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-border-color{border-color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-border-color{border-color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-border-color{border-color: var(--wp--preset--color--vivid-purple) !important;}.has-vivid-cyan-blue-to-vivid-purple-gradient-background{background: var(--wp--preset--gradient--vivid-cyan-blue-to-vivid-purple) !important;}.has-light-green-cyan-to-vivid-green-cyan-gradient-background{background: var(--wp--preset--gradient--light-green-cyan-to-vivid-green-cyan) !important;}.has-luminous-vivid-amber-to-luminous-vivid-orange-gradient-background{background: var(--wp--preset--gradient--luminous-vivid-amber-to-luminous-vivid-orange) !important;}.has-luminous-vivid-orange-to-vivid-red-gradient-background{background: var(--wp--preset--gradient--luminous-vivid-orange-to-vivid-red) !important;}.has-very-light-gray-to-cyan-bluish-gray-gradient-background{background: var(--wp--preset--gradient--very-light-gray-to-cyan-bluish-gray) !important;}.has-cool-to-warm-spectrum-gradient-background{background: var(--wp--preset--gradient--cool-to-warm-spectrum) !important;}.has-blush-light-purple-gradient-background{background: var(--wp--preset--gradient--blush-light-purple) !important;}.has-blush-bordeaux-gradient-background{background: var(--wp--preset--gradient--blush-bordeaux) !important;}.has-luminous-dusk-gradient-background{background: var(--wp--preset--gradient--luminous-dusk) !important;}.has-pale-ocean-gradient-background{background: var(--wp--preset--gradient--pale-ocean) !important;}.has-electric-grass-gradient-background{background: var(--wp--preset--gradient--electric-grass) !important;}.has-midnight-gradient-background{background: var(--wp--preset--gradient--midnight) !important;}.has-small-font-size{font-size: var(--wp--preset--font-size--small) !important;}.has-medium-font-size{font-size: var(--wp--preset--font-size--medium) !important;}.has-large-font-size{font-size: var(--wp--preset--font-size--large) !important;}.has-x-large-font-size{font-size: var(--wp--preset--font-size--x-large) !important;} .wp-block-navigation a:where(:not(.wp-element-button)){color: inherit;} :where(.wp-block-columns.is-layout-flex){gap: 2em;} .wp-block-pullquote{font-size: 1.5em;line-height: 1.6;} </style> <link rel='stylesheet' id='qm-object-cache-style-css' href='https://www.msd.de/wp-content/mu-plugins/qm-plugins/qm-object-cache/css/style.css?ver=0.2' media='all' /> <link rel='stylesheet' id='MCC-styles-default-font-css' href='https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/css/default-font.min.css?ver=1727712659' media='all' /> <link rel='stylesheet' id='MCC-styles-css' href='https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/css/style.min.css?ver=1732907425' media='all' /> <link rel='stylesheet' id='footer-flagship-standard-css' href='https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/css/footer-flagship-standard.min.css?ver=1724751469' media='all' /> <link rel='stylesheet' id='mcc_header_style-css' href='https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/css/masthead-country-1.min.css?ver=1724751469' media='all' /> <link rel='stylesheet' id='banner-styles-css' href='https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/css/bottom-banner.min.css?ver=6.2.6' media='all' /> <link rel='stylesheet' id='inpsyde.brightcove.front-office-style-css' href='https://www.msd.de/wp-content/plugins/cex-wpvip-brightcove/assets/inpsyde-brightcove.css?ver=1732907102' media='all' /> <script defer="defer" src="//cdn.cookielaw.org/scripttemplates/otSDKStub.js?ver=6.2.6" data-domain-script="718071b8-d94a-4043-9122-6e242f1f4ce9"></script><script>function OptanonWrapper() { }</script><link rel="https://api.w.org/" href="https://www.msd.de/wp-json/" /><link rel="alternate" type="application/json" href="https://www.msd.de/wp-json/wp/v2/pages/1396" /><link rel='shortlink' href='https://www.msd.de/?p=1396' /> <link rel="alternate" type="application/json+oembed" href="https://www.msd.de/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww.msd.de%2Fforschung-und-arzneimittel%2Fhintergrundwissen%2F" /> <link rel="alternate" type="text/xml+oembed" href="https://www.msd.de/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww.msd.de%2Fforschung-und-arzneimittel%2Fhintergrundwissen%2F&format=xml" />  <script> (function(w, d, s, l, i) { w[l] = w[l] || []; w[l].push({ 'gtm.start': new Date().getTime(), event: 'gtm.js' }); var f = d.getElementsByTagName(s)[0], j = d.createElement(s), dl = l != 'dataLayer' ? '&l=' + l : ''; j.async = true; j.src = 'https://www.googletagmanager.com/gtm.js?id=' + i + dl; f.parentNode.insertBefore(j, f); })(window, document, 'script', 'dataLayer', 'GTM-MZG3KZL') </script>   <meta name="ga4_page_audience" content="untaggable" /><meta name="ga4_page_content_purpose" content="resources and tools" /><meta name="ga4_page_customer_journey_stage" content="awareness" /><meta name="ga4_page_customer_specialty" content="other" /><meta name="ga4_page_product" content="corporate" /><meta name="ga4_page_region" content="eucan" /><meta name="ga4_page_cmsplatform" content="WP-VIP" /><meta name="ga4_page_cmstheme" content="Corporate" /><meta name="ga4_page_accessibility" content="publish" /><meta name="ga4_page_wpid" content="1396" /><meta name="ga4_page_language" content="en_US" /><meta name="ga4_page_title" content="hintergrundwissen" /><script> var dataLayer = dataLayer || []; dataLayer.push({"ga4":{"ga4_page_audience":"untaggable","ga4_page_content_purpose":"resources and tools","ga4_page_customer_journey_stage":"awareness","ga4_page_customer_specialty":"other","ga4_page_product":"corporate","ga4_page_region":"eucan","ga4_page_cmsplatform":"wp-vip","ga4_page_cmstheme":"corporate","ga4_page_language":"en_us"}}); dataLayer.push({"user":{"role":"visitor","isLoggedIn":false}}); dataLayer.push({"site":[]}); </script> <script> ( function( w, d, s, l, i ) { w[l] = w[l] || []; w[l].push( {'gtm.start': new Date().getTime(), event: 'gtm.js'} ); var f = d.getElementsByTagName( s )[0], j = d.createElement( s ), dl = l !== 'dataLayer' ? '&l=' + l : ''; j.async = true; j.src = 'https://www.googletagmanager.com/gtm.js?id=' + i + dl; f.parentNode.insertBefore( j, f ); } )( window, document, 'script', 'dataLayer', 'GTM-MZG3KZL' ); </script> <link rel="apple-touch-icon" sizes="180x180" href="https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/images/apple-touch-icon.png"> <link rel="icon" type="image/png" sizes="32x32" href="https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/images/favicon-32x32.png"> <link rel="icon" type="image/png" sizes="16x16" href="https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/images/favicon-16x16.png"> <link rel="manifest" href="https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/images/site.webmanifest"> <link rel="mask-icon" href="https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/images/safari-pinned-tab.svg" color="#ffffff"> <link rel="shortcut icon" href="https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/images/favicon.ico"> <meta name="msapplication-TileColor" content="#ffffff"> <meta name="msapplication-config" content="https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/images/browserconfig.xml"> <meta name="theme-color" content="#ffffff"> <style> :root { --colorTextPrimary: #000000; --colorPrimary: #00857C; --colorPrimaryLight: #6ECEB2; --colorPrimaryDark: #005C55; --colorPrimaryDarkBlue: #0C2340; --colorSecondaryLime: #BFED33; --colorSecondaryLemon: #FFF063; --colorSecondaryPastelBlue: #69B8F7; --colorSecondaryVistaBlue: #688CE8; --colorSecondaryRichBlue: #5450E4; --colorBlack: #000000; --colorWhite: #FFFFFF; --colorOffWhite: #F7F7F7; --colorGray: #757575; --colorWarning: #FE0000; --colorSuccess: #029A01; --colorInfo: #1058A4; --colorGrayHRTwenty: #75757533; --colorGrayHRTen: #7575751a; } </style></head> <body class="page-template-default page page-id-1396 page-child parent-pageid-5815 no-sidebar"> <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-MZG3KZL&ga4%5Bga4_page_audience%5D=untaggable&ga4%5Bga4_page_content_purpose%5D=resources+and+tools&ga4%5Bga4_page_customer_journey_stage%5D=awareness&ga4%5Bga4_page_customer_specialty%5D=other&ga4%5Bga4_page_product%5D=corporate&ga4%5Bga4_page_region%5D=eucan&ga4%5Bga4_page_cmsplatform%5D=wp-vip&ga4%5Bga4_page_cmstheme%5D=corporate&ga4%5Bga4_page_language%5D=en_us&user%5Brole%5D=visitor&user%5BisLoggedIn%5D=0&" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 0 0" width="0" height="0" focusable="false" role="none" style="visibility: hidden; position: absolute; left: -9999px; overflow: hidden;" ><defs><filter id="wp-duotone-dark-grayscale"><feColorMatrix color-interpolation-filters="sRGB" type="matrix" values=" .299 .587 .114 0 0 .299 .587 .114 0 0 .299 .587 .114 0 0 .299 .587 .114 0 0 " /><feComponentTransfer color-interpolation-filters="sRGB" ><feFuncR type="table" tableValues="0 0.49803921568627" /><feFuncG type="table" tableValues="0 0.49803921568627" /><feFuncB type="table" tableValues="0 0.49803921568627" /><feFuncA type="table" tableValues="1 1" /></feComponentTransfer><feComposite in2="SourceGraphic" operator="in" /></filter></defs></svg><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 0 0" width="0" height="0" focusable="false" role="none" style="visibility: hidden; position: absolute; left: -9999px; overflow: hidden;" ><defs><filter id="wp-duotone-grayscale"><feColorMatrix color-interpolation-filters="sRGB" type="matrix" values=" .299 .587 .114 0 0 .299 .587 .114 0 0 .299 .587 .114 0 0 .299 .587 .114 0 0 " /><feComponentTransfer color-interpolation-filters="sRGB" ><feFuncR type="table" tableValues="0 1" /><feFuncG type="table" tableValues="0 1" /><feFuncB type="table" tableValues="0 1" /><feFuncA type="table" tableValues="1 1" /></feComponentTransfer><feComposite in2="SourceGraphic" operator="in" /></filter></defs></svg><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 0 0" width="0" height="0" focusable="false" role="none" style="visibility: hidden; position: absolute; left: -9999px; overflow: hidden;" ><defs><filter id="wp-duotone-purple-yellow"><feColorMatrix color-interpolation-filters="sRGB" type="matrix" values=" .299 .587 .114 0 0 .299 .587 .114 0 0 .299 .587 .114 0 0 .299 .587 .114 0 0 " /><feComponentTransfer color-interpolation-filters="sRGB" ><feFuncR type="table" tableValues="0.54901960784314 0.98823529411765" /><feFuncG type="table" tableValues="0 1" /><feFuncB type="table" tableValues="0.71764705882353 0.25490196078431" /><feFuncA type="table" tableValues="1 1" /></feComponentTransfer><feComposite in2="SourceGraphic" operator="in" /></filter></defs></svg><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 0 0" width="0" height="0" focusable="false" role="none" style="visibility: hidden; position: absolute; left: -9999px; overflow: hidden;" ><defs><filter id="wp-duotone-blue-red"><feColorMatrix color-interpolation-filters="sRGB" type="matrix" values=" .299 .587 .114 0 0 .299 .587 .114 0 0 .299 .587 .114 0 0 .299 .587 .114 0 0 " /><feComponentTransfer color-interpolation-filters="sRGB" ><feFuncR type="table" tableValues="0 1" /><feFuncG type="table" tableValues="0 0.27843137254902" /><feFuncB type="table" tableValues="0.5921568627451 0.27843137254902" /><feFuncA type="table" tableValues="1 1" /></feComponentTransfer><feComposite in2="SourceGraphic" operator="in" /></filter></defs></svg><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 0 0" width="0" height="0" focusable="false" role="none" style="visibility: hidden; position: absolute; left: -9999px; overflow: hidden;" ><defs><filter id="wp-duotone-midnight"><feColorMatrix color-interpolation-filters="sRGB" type="matrix" values=" .299 .587 .114 0 0 .299 .587 .114 0 0 .299 .587 .114 0 0 .299 .587 .114 0 0 " /><feComponentTransfer color-interpolation-filters="sRGB" ><feFuncR type="table" tableValues="0 0" /><feFuncG type="table" tableValues="0 0.64705882352941" /><feFuncB type="table" tableValues="0 1" /><feFuncA type="table" tableValues="1 1" /></feComponentTransfer><feComposite in2="SourceGraphic" operator="in" /></filter></defs></svg><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 0 0" width="0" height="0" focusable="false" role="none" style="visibility: hidden; position: absolute; left: -9999px; overflow: hidden;" ><defs><filter id="wp-duotone-magenta-yellow"><feColorMatrix color-interpolation-filters="sRGB" type="matrix" values=" .299 .587 .114 0 0 .299 .587 .114 0 0 .299 .587 .114 0 0 .299 .587 .114 0 0 " /><feComponentTransfer color-interpolation-filters="sRGB" ><feFuncR type="table" tableValues="0.78039215686275 1" /><feFuncG type="table" tableValues="0 0.94901960784314" /><feFuncB type="table" tableValues="0.35294117647059 0.47058823529412" /><feFuncA type="table" tableValues="1 1" /></feComponentTransfer><feComposite in2="SourceGraphic" operator="in" /></filter></defs></svg><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 0 0" width="0" height="0" focusable="false" role="none" style="visibility: hidden; position: absolute; left: -9999px; overflow: hidden;" ><defs><filter id="wp-duotone-purple-green"><feColorMatrix color-interpolation-filters="sRGB" type="matrix" values=" .299 .587 .114 0 0 .299 .587 .114 0 0 .299 .587 .114 0 0 .299 .587 .114 0 0 " /><feComponentTransfer color-interpolation-filters="sRGB" ><feFuncR type="table" tableValues="0.65098039215686 0.40392156862745" /><feFuncG type="table" tableValues="0 1" /><feFuncB type="table" tableValues="0.44705882352941 0.4" /><feFuncA type="table" tableValues="1 1" /></feComponentTransfer><feComposite in2="SourceGraphic" operator="in" /></filter></defs></svg><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 0 0" width="0" height="0" focusable="false" role="none" style="visibility: hidden; position: absolute; left: -9999px; overflow: hidden;" ><defs><filter id="wp-duotone-blue-orange"><feColorMatrix color-interpolation-filters="sRGB" type="matrix" values=" .299 .587 .114 0 0 .299 .587 .114 0 0 .299 .587 .114 0 0 .299 .587 .114 0 0 " /><feComponentTransfer color-interpolation-filters="sRGB" ><feFuncR type="table" tableValues="0.098039215686275 1" /><feFuncG type="table" tableValues="0 0.66274509803922" /><feFuncB type="table" tableValues="0.84705882352941 0.41960784313725" /><feFuncA type="table" tableValues="1 1" /></feComponentTransfer><feComposite in2="SourceGraphic" operator="in" /></filter></defs></svg><div id="page" class="site"> <a class="skip-link screen-reader-text" href="#content">Skip to content</a> <header id="masthead" class="site-header"> <nav id="site-navigation" class="main-navigation"> <div class="wrapper header-wrapper"> <div class="site-branding"> <p class="site-title"> <a id="micro-site-logo" href="https://www.msd.de/" rel="home" class="site-logo-link" title="msd.de" style="" > <img class="site-logo" src="https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/images/msd-logo.svg" alt="Site logo" style="" /> </a> </p></div> <div id="mastheadMenu"> <button id="siteSearchToggle" class="btn" aria-controls="site-search" aria-expanded="false"> <span class="menu-toggle-text-open"> <img src="https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/images/search-white.svg" alt="menu icon" /> <span>Suchen</span> </span> <span class="menu-toggle-text-close"> <img class="lazyload" loading="lazy" data-src="https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/images/close.svg" alt="close icon" />Schließen </span> </button> <button id="siteNavigationToggle" class="btn menu-toggle" aria-controls="menuMain" aria-expanded="false"> <span class="menu-toggle-text-open"> <img src="https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/images/burger-white.svg" alt="menu icon" />Menü </span> <span class="menu-toggle-text-close"> <img class="lazyload" loading="lazy" data-src="https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/images/close.svg" alt="close icon" />Schließen </span> </button> </div> </div> </nav> <nav id="site-menu" class="main-menu menu-header-template"> <div class="wrapper"> <a class="menucrumb" href="#">Main menu</a> <div class="menu-main-menu-container"><ul id="menuMain" class="menu-main level-0 menu-open"><li id="menu-item-5833" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-5833"><a href="https://www.msd.de/ueber-msd/">Über MSD</a> <ul class="level-1"> <li id="menu-item-668" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-668"><a href="https://www.msd.de/ueber-msd/msd-auf-einen-blick/">MSD auf einen Blick</a></li> <li id="menu-item-667" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-667"><a href="https://www.msd.de/ueber-msd/unsere-motivation/">Unsere Motivation</a></li> <li id="menu-item-669" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-669"><a href="https://www.msd.de/ueber-msd/unsere-meilensteine/">Unsere Meilensteine</a></li> <li id="menu-item-670" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-670"><a href="https://www.msd.de/ueber-msd/unser-arbeitsumfeld/">Unser Arbeitsumfeld</a></li> <li id="menu-item-10711" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-10711"><a href="https://www.msd.de/ueber-msd/nachhaltigkeit/">Nachhaltigkeit</a></li> <li id="menu-item-2363" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2363"><a href="https://www.msd.de/ueber-msd/msd-im-blog/">MSD im Blog</a></li> </ul> </li> <li id="menu-item-5818" class="menu-item menu-item-type-post_type menu-item-object-page current-page-ancestor current-menu-ancestor current-page-parent current_page_ancestor menu-item-has-children menu-item-5818"><a href="https://www.msd.de/forschung-und-arzneimittel/">Forschung und Arzneimittel</a> <ul class="level-1"> <li id="menu-item-25928" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-25928"><a href="https://www.msd.de/forschung-und-arzneimittel/arzneimitteldatenbank/">Medikamente und Impfstoffe</a></li> <li id="menu-item-2348" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2348"><a href="https://www.msd.de/forschung-und-arzneimittel/forschung-bei-msd/">Forschung bei MSD</a></li> <li id="menu-item-5819" class="menu-item menu-item-type-post_type menu-item-object-page current-page-ancestor current-page-parent menu-item-has-children menu-item-5819"><a href="https://www.msd.de/forschung-und-arzneimittel/">Unsere Therapiegebiete</a> <ul class="level-2"> <li id="menu-item-828" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-828"><a href="https://www.msd.de/forschung-und-arzneimittel/onkologie/">Onkologie</a></li> <li id="menu-item-2376" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2376"><a href="https://www.msd.de/forschung-und-arzneimittel/impfstoffe/">Impfstoffe</a></li> <li id="menu-item-698" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-698"><a href="https://www.msd.de/forschung-und-arzneimittel/infektionskrankheiten/">Infektionskrankheiten</a></li> </ul> </li> <li id="menu-item-701" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-701"><a target="_blank" rel="noopener" href="https://www.msd.com/research/product-pipeline/">MSD Pipeline</a></li> <li id="menu-item-5820" class="menu-item menu-item-type-post_type menu-item-object-page current-page-ancestor current-menu-ancestor current-menu-parent current-page-parent current_page_parent current_page_ancestor menu-item-has-children menu-item-5820"><a href="https://www.msd.de/forschung-und-arzneimittel/">Klinische Forschung</a> <ul class="level-2"> <li id="menu-item-1874" class="menu-item menu-item-type-post_type menu-item-object-page current-menu-item page_item page-item-1396 current_page_item menu-item-1874 current "><a href="https://www.msd.de/forschung-und-arzneimittel/hintergrundwissen/" aria-current="page">Hintergrundwissen</a></li> <li id="menu-item-1881" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1881"><a href="https://www.msd.de/forschung-und-arzneimittel/informationen-fuer-pruefaerzte/">Informationen für Prüfärzte</a></li> <li id="menu-item-18112" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-18112"><a href="https://www.msd.de/forschung-und-arzneimittel/klinische-studien/">Klinische Studien von MSD</a></li> </ul> </li> <li id="menu-item-1893" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1893"><a target="_blank" rel="noopener" href="https://www.msdconnect.de/">MSD Ärzteportal</a></li> <li id="menu-item-8892" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-8892"><a href="https://www.msd.de/forschung-und-arzneimittel/informationen-fuer-apotheker/">Kundenportal für Apotheken</a></li> </ul> </li> <li id="menu-item-5840" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-5840"><a href="https://www.msd.de/msd-fuer-patienten/">MSD für Patienten</a> <ul class="level-1"> <li id="menu-item-702" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-702"><a href="https://www.msd.de/msd-fuer-patienten/msd-mit-patienten/">MSD mit Patienten</a></li> <li id="menu-item-2354" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2354"><a href="https://www.msd.de/msd-fuer-patienten/gesundheitskompetenz/">Gesundheitskompetenz</a></li> <li id="menu-item-703" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-703"><a href="https://www.msd.de/msd-fuer-patienten/mit-patienten-im-dialog/">Mit Patienten im Dialog</a></li> <li id="menu-item-1885" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1885"><a href="https://www.msd.de/msd-fuer-patienten/patientensicherheit/">Patientensicherheit</a></li> <li id="menu-item-1892" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1892"><a target="_blank" rel="noopener" href="http://www.msd-gesundheit.de">MSD Patientenportal</a></li> <li id="menu-item-19746" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-19746"><a href="https://www.msd.de/msd-fuer-patienten/vorsorge/">Vorsorge statt Sorge</a></li> </ul> </li> <li id="menu-item-5824" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-5824"><a href="https://www.msd.de/politik-und-verantwortung/">Politik und Verantwortung</a> <ul class="level-1"> <li id="menu-item-2366" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2366"><a href="https://www.msd.de/politik-und-verantwortung/transparenz-bei-msd/">Transparenz bei MSD</a></li> <li id="menu-item-5825" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-5825"><a href="https://www.msd.de/politik-und-verantwortung/">Politik und Dialog</a> <ul class="level-2"> <li id="menu-item-1912" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1912"><a href="https://www.msd.de/politik-und-verantwortung/prinzipien-und-ziele-unserer-politischen-arbeit/">Prinzipien und Ziele unserer politischen Arbeit</a></li> <li id="menu-item-1909" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1909"><a href="https://www.msd.de/politik-und-verantwortung/unser-team-in-berlin-und-muenchen/">Unser Team in Berlin und München</a></li> <li id="menu-item-1906" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1906"><a href="https://www.msd.de/politik-und-verantwortung/positionen-und-themen/">Positionen und Themen</a></li> </ul> </li> <li id="menu-item-18170" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-18170"><a href="https://www.msd.de/gesundheitspreis/">MSD Gesundheitspreis</a></li> <li id="menu-item-16739" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-16739"><a href="https://www.msd.de/msd-gesundheitsforum/">MSD Gesundheitsforum</a></li> </ul> </li> <li id="menu-item-5837" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-5837"><a href="https://www.msd.de/karriere/">Karriere</a> <ul class="level-1"> <li id="menu-item-1938" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1938"><a href="https://www.msd.de/karriere/standorte-und-jobprofile/">Standorte und Jobprofile</a></li> <li id="menu-item-1994" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1994"><a href="https://www.msd.de/karriere/msd-als-arbeitgeber/">MSD als Arbeitgeber</a></li> <li id="menu-item-1941" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1941"><a href="https://www.msd.de/karriere/karrierewege-bei-msd/">Karrierewege bei MSD</a></li> <li id="menu-item-775" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-775"><a target="_blank" rel="noopener" href="https://jobs.msd.com/de/de/germany-job-search?utm_source=msd&utm_medium=website&camp_ind=corp&utm_campaign=navi-jobsuche-de">Zur Jobsuche</a></li> <li id="menu-item-1937" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1937"><a href="https://www.msd.de/karriere/faqs-zur-bewerbung/">FAQs zur Bewerbung</a></li> <li id="menu-item-22839" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-22839"><a href="https://www.msd.de/digital/">Jobs im MSD Digital Team</a></li> <li id="menu-item-22836" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-22836"><a href="https://www.msd.de/produktion/">Arbeiten in der Produktion</a></li> </ul> </li> <li id="menu-item-5834" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-5834"><a href="https://www.msd.de/newsroom/">Newsroom</a> <ul class="level-1"> <li id="menu-item-705" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-705"><a href="https://www.msd.de/newsroom/pressemitteilungen/">Pressemitteilungen</a></li> <li id="menu-item-706" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-706"><a href="https://www.msd.de/newsroom/pressekontakte/">Pressekontakte</a></li> </ul> </li> </ul></div> <div class="side-section"> </div> <div class="bottom-section"> <a class="btn" href="https://www.msd.de/kontakt/" title="Kontakt" target="" rel="noopener" >Kontakt</a> <p> <a href="https://www.msd.com/contact-us/worldwide-locations/" rel="noopener" target="_blank" class="" style="background: none !important;">MSD Weltweit</a> <small>See our worldwide locations and country contact information</small> </p> </div> </div> </nav> <form id="site-search" role="search" method="get" class="search-form" action="https://www.msd.de" autocomplete="off"> <h2>Was können wir für Sie finden?</h2> <div id="site-search-box" class="input-box"> <span class="screen-reader-text">Suche nach: </span> <input type="text" class="search-field" placeholder="Ich suche ..." value="" name="s" aria-label="Seite durchsuchen"> <button type="submit" class="submit search-submit"></button> </div> </form> </header> <div id="content" class="site-content"> <div id="primary" class="content-area"> <main id="main" class="site-main"> <article id="post-1396" class="post-1396 page type-page status-publish hentry"> <div class="entry-content"> <div id="mco-b2-hero-block-block_dcc7170d3f59a1bd0e72cb14115d063f" class="mco-b2-hero-block full mccberg-block pl-2"> <div class="mco-b2-hero-block-wrapper"> <div class="mco-b2-hero-block-image-section "> <div class="mco-b2-hero-block-image-container mco-b2-hero-block-toggle-btn"> <picture> <source media="(max-width: 767px)" data-srcset="https://www.msd.de/wp-content/uploads/sites/33/2021/10/17425285_Labor-2048x1365px.jpg?resize=348,324"> <source media="(min-width: 768px) and (max-width: 1279px)" data-srcset="https://www.msd.de/wp-content/uploads/sites/33/2021/10/17425285_Labor-2048x1365px.jpg?resize=341,524"> <source media="(min-width: 1280px)" data-srcset="https://www.msd.de/wp-content/uploads/sites/33/2021/10/17425285_Labor-2048x1365px.jpg?resize=666,664"> <img data-src="https://www.msd.de/wp-content/uploads/sites/33/2021/10/17425285_Labor-2048x1365px.jpg?resize=666,664" alt="Hero Image" class="eager" loading="eager" /> </picture> <div class='mco-b2-hero-block-play-button btn-play'></div><div class='mco-b2-hero-block-video-type' style='display: none;'>youtube</div><div class='mco-b2-hero-block-youtube-url' style='display: none;'></div><div class='mco-b2-hero-block-brightcove-info' style='display: none;'>:</div> </div> <div class="mco-b2-hero-block-image-container-two"> <div class='mco-b2-hero-block-green-box'></div> </div> </div> <div class="mco-b2-hero-block-content-section"> <div class="breadcrumbs wrapper text-descriptive"><span><span><a href="https://www.msd.de/forschung-und-arzneimittel/">Forschung und Arzneimittel</a></span> > <span class="breadcrumb_last" aria-current="page">Hintergrundwissen</span></span></div> <h1>Der lange Weg zum Medikament</h1> <div class="mco-b2-hero-block-description"><p>Unsere Arbeit dreht sich um das höchste Gut des Menschen: die Gesundheit. Wir forschen weiter an neuen Medikamenten und Impfstoffen, um immer mehr Menschen weltweit helfen zu können. Bevor es jedoch so weit ist, wird ein Arzneimittel in mehreren Studienphasen umfassend auf Sicherheit und Wirksamkeit geprüft.</p> </div> </div> </div> </div> <div class="mco-b2-hero-block-modal popup" style="display: none;"> <div class="popup-wrapper"> <div class="mco-b2-hero-block-modal-content popup-content"> </div> </div> </div> <script> let b2_hero_block_modal_triggers = document.getElementsByClassName('mco-b2-hero-block-toggle-btn'); let b2_hero_block_video_type = document.getElementsByClassName('mco-b2-hero-block-video-type'); let b2_hero_block_youtube_url = document.getElementsByClassName('mco-b2-hero-block-youtube-url'); let b2_hero_block_brightcove_info = document.getElementsByClassName('mco-b2-hero-block-brightcove-info'); let b2_hero_block_modals = document.getElementsByClassName('mco-b2-hero-block-modal'); for (let i = 0; i < b2_hero_block_modal_triggers.length; i++) { let trigger = b2_hero_block_modal_triggers[i]; let video_type = b2_hero_block_video_type[i].textContent; let youtube_url = b2_hero_block_youtube_url[i].textContent; let brightcove_info = b2_hero_block_brightcove_info[i].textContent; let modal = b2_hero_block_modals[i]; let modal_content_div = modal.getElementsByClassName('mco-b2-hero-block-modal-content')[0]; trigger.addEventListener('click', function () { if (modal.style.display === 'none') { // Load Video Content if (video_type === 'youtube') { // Insert YouTube Iframe into Div let youtube_video_id = youtube_url.split('=')[1].split('&')[0] modal_content_div.innerHTML = `<iframe width='933' height='525' src='https://www.youtube.com/embed/${youtube_video_id}' frameborder='0' allow='accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture' allowfullscreen></iframe>`; } else { // Insert Brightcove Video Info Into Div let account_id = brightcove_info.split(":")[0]; let video_id = brightcove_info.split(":")[1]; modal_content_div.innerHTML = `<video class='video-js vjs-fluid mco-featured-stories-e1-video' data-account='${account_id}' data-player='default' data-embed='default' controls='' data-video-id='${video_id}' data-playlist-id='' data-application-id='' width='960' height='540'></video>`; let brightcove_videos = document.getElementsByClassName("mco-featured-stories-e1-video"); for (let i = 0; i < brightcove_videos.length; i++) { let video = brightcove_videos[i]; let script = document.createElement("script"); script.async = true; script.src = "https://players.brightcove.net/" + account_id + "/default_default/index.min.js"; video.parentNode.insertBefore(script, video.nextSibling); } } } modal.style.display = modal.style.display === "none" ? "block" : "none"; }); modal.addEventListener('click', function (e) { if (e.target.classList.contains("mco-b2-hero-block-modal") || e.target.classList.contains('popup-wrapper')) { modal.setAttribute('style', 'display: none;'); if (video_type === "youtube") { var iframe = modal_content_div.getElementsByTagName("iframe")[0]; var video_src = iframe.getAttribute('src'); iframe.setAttribute("src", " "); iframe.setAttribute("src", video_src); } else { var videoPlayer = modal_content_div.firstChild.getElementsByTagName("video")[0]; videoPlayer.pause(); } } }); } </script> <div class="wp-block-group is-layout-flow"><div class="wp-block-group__inner-container"> <h3 class="wp-block-heading has-text-align-center">Präklinische Phase</h3> <p class="has-text-align-center">Mithilfe modernster Wissenschaft analysieren wir Erkrankungen aus verschiedensten Blickwinkeln, um so einen Ansatzpunkt für Medikamente zu finden. Im Labor entwickeln Wissenschaftler:innen tausende Moleküle und testen diese z.B. an Zellkulturen, um herauszufinden, ob diese wirksam und sicher sein können.</p> <div style="height:46px" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-columns is-layout-flex wp-container-3"> <div class="wp-block-column pl-2 pr-2 pt-2 pb-2 is-layout-flow"><div class="wp-block-image"> <figure class="aligncenter size-large is-resized"><img decoding="async" loading="lazy" src="https://www.msd.de/wp-content/uploads/sites/33/2021/10/family2.png?w=313" alt="Icon with family" class="wp-image-9977" width="157" height="143"/></figure></div> <h4 class="wp-block-heading">1. Medizinischen Bedarf erkennen</h4> <p>Am Anfang steht die Entscheidung, ein neues Medikament für Patient:innen zu entwickeln, die zum Beispiel an einer bisher nicht gut behandelbaren Krankheit leiden.</p> </div> <div class="wp-block-column pl-2 pr-2 pt-2 pb-2 is-layout-flow"><div class="wp-block-image"> <figure class="aligncenter size-large is-resized"><img decoding="async" loading="lazy" src="https://www.msd.de/wp-content/uploads/sites/33/2021/10/cell-korr.png?w=286" alt="Icon with cell" class="wp-image-9686" width="143" height="143"/></figure></div> <h4 class="wp-block-heading">2. Wirkansatz finden</h4> <p>Forscher:innen ermitteln, welche Moleküle in unserem Körper bei der Entwicklung einer Krankheit eine entscheidende Rolle spielen. Mit diesem Wissen identifizieren sie therapeutische Ansatzpunkte, um das Krankheitsgeschehen zu beeinflussen.</p> </div> </div> <div class="wp-block-columns is-layout-flex wp-container-6"> <div class="wp-block-column is-layout-flow"><div class="wp-block-image"> <figure class="aligncenter size-large is-resized"><img decoding="async" loading="lazy" src="https://www.msd.de/wp-content/uploads/sites/33/2021/10/three-test-tubes.png?w=325" alt="Icon with laboratory tubes" class="wp-image-9695" width="163" height="143"/></figure></div> <h4 class="wp-block-heading">3. Erkennen von geeigneten möglichen Wirkstoffen</h4> <p>Wissenschaftler:innen identifizieren Substanzen, die in ein Krankheitsgeschehen eingreifen könnten. Zielsetzungen können die Heilung oder Linderung der Krankheit sein. Auch eine verbesserte Lebensqualität von Patient:innnen ist ein mögliches, sehr wichtiges Forschungsziel.</p> </div> <div class="wp-block-column is-layout-flow"><div class="wp-block-image"> <figure class="aligncenter size-large is-resized"><img decoding="async" loading="lazy" src="https://www.msd.de/wp-content/uploads/sites/33/2021/10/syringe.png?w=286" alt="Icon with syringe" class="wp-image-9696" width="143" height="143"/></figure></div> <h4 class="wp-block-heading">4. Erste Prüfung auf Wirksamkeit und Verträglichkeit außerhalb des Menschen</h4> <p>Die erfolgversprechendsten Substanzen werden zunächst in Zellkulturen und/oder Tieren geprüft, ob sie wirksam, nicht giftig oder anderweitig schädlich sind. Wirkstoffe, die in dieser präklinischen Phase erfolgreich sind, können in weiteren klinischen Phasen untersucht werden.</p> </div> </div> </div></div> <div style="height:46px" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-group is-layout-flow"><div class="wp-block-group__inner-container"> <h3 class="wp-block-heading has-text-align-center">Klinische Phase</h3> <p class="has-text-align-center">Erst wenn ein Wirkstoffkandidat alle Tests der präklinischen Phase positiv abgeschlossen hat, kann er in der klinischen Phase erstmals an Menschen angewandt werden. Für klinische Studien ist die Zustimmung der zuständigen nationalen Behörden und der Ethikkommissionen nötig. In allen Phasen der Studie müssen die Teilnehmenden umfassend aufgeklärt und über mögliche Risiken informiert werden. Die Studienteilnahme ist zu jeder Zeit freiwillig.</p> <div style="height:46px" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-columns is-layout-flex wp-container-10"> <div class="wp-block-column is-layout-flow"><div class="wp-block-image"> <figure class="aligncenter size-large is-resized"><img decoding="async" loading="lazy" src="https://www.msd.de/wp-content/uploads/sites/33/2021/10/diploma.png?w=268" alt="Icon with certificate" class="wp-image-9720" width="134" height="143"/></figure></div> <h4 class="wp-block-heading">5. Begutachtung durch Zulassungsbehörden und Ethikkommissionen</h4> <p>Vor jeder Phase klinischer Studien prüfen ausgewählte Gremien die Studienprotokolle. Sie bewerten aus ethischer, medizinischer und rechtlicher Sicht, ob eine Studie durchgeführt werden darf. Auch während der klinischen Prüfung werden die Daten kontinuierlich überwacht.</p> </div> <div class="wp-block-column is-layout-flow"><div class="wp-block-image"> <figure class="aligncenter size-large is-resized"><img decoding="async" loading="lazy" src="https://www.msd.de/wp-content/uploads/sites/33/2021/10/parents2.png?w=303" alt="Icon with family" class="wp-image-9684" width="152" height="143"/></figure></div> <h4 class="wp-block-heading">6. Phase I: Studie mit wenigen gesunden Erwachsenen</h4> <p>In Phase I wird ein neuer Wirkstoff an einer kleinen Gruppe freiwilliger gesunder Erwachsener (Probanden) geprüft. Die Phase-I-Studie dient u.a. dazu, die Aufnahme und den Abbau der Substanz im Körper engmaschig zu überwachen. Zusätzlich werden alle Symptome, Nebenwirkungen und das allgemeine Wohlbefinden der Probanden beobachtet.</p> </div> </div> <div class="wp-block-columns is-layout-flex wp-container-13"> <div class="wp-block-column is-layout-flow"><div class="wp-block-image"> <figure class="aligncenter size-large is-resized"><img decoding="async" loading="lazy" src="https://www.msd.de/wp-content/uploads/sites/33/2021/10/parents2.png?w=303" alt="Icon with family" class="wp-image-9684" width="152" height="143"/></figure></div> <h4 class="wp-block-heading">7. Phase II: Studie mit wenigen kranken Erwachsenen.</h4> <p>In einer Phase-II-Studie erhalten Erkrankte entweder das neue Medikament oder eine Vergleichsbehandlung. Die Zahl der Teilnehmenden ist höher als in Phase I. In Phase II werden Wirksamkeit und Verträglichkeit sowie die ideale Dosierung bei realen Patient:innen ermittelt.<br></p> </div> <div class="wp-block-column is-layout-flow"><div class="wp-block-image"> <figure class="aligncenter size-large is-resized"><img decoding="async" loading="lazy" src="https://www.msd.de/wp-content/uploads/sites/33/2021/10/team1.png?w=334" alt="Icon with many people" class="wp-image-9723" width="167" height="143"/></figure></div> <h4 class="wp-block-heading">8. Phase III: Studien mit vielen kranken Erwachsenen</h4> <p>In Phase-III-Studien wird eine große Anzahl Patient:innen aufgenommen, die möglichst repräsentativ für das spätere Patientenklientel sein sollen. Wirksamkeit und Sicherheit werden untersucht. Wegen der großen Patientenzahl können auch seltenere Neben- und Wechselwirkungen erkannt werden. Zusätzlich werden besondere Kriterien für das Krankheitsbild untersucht wie zum Beispiel die Lebensqualität.</p> </div> </div> </div></div> <div style="height:46px" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-group is-layout-flow"><div class="wp-block-group__inner-container"> <h3 class="wp-block-heading has-text-align-center">Zulassung und Beobachtung in der Praxis</h3> <p class="has-text-align-center">Nach Abschluss der klinischen Studien entscheiden die Zulassungsbehörden darüber, ob ein Medikament eingeführt und eingesetzt werden darf. Außerdem überwachen Behörden, Hersteller und Ärzt:innen das Medikament auch weiterhin.</p> <div style="height:46px" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-columns is-layout-flex wp-container-17"> <div class="wp-block-column is-layout-flow"><div class="wp-block-image"> <figure class="aligncenter size-large is-resized"><img decoding="async" loading="lazy" src="https://www.msd.de/wp-content/uploads/sites/33/2021/10/search2.png?w=288" alt="icons with certificates" class="wp-image-9742" width="144" height="143"/></figure></div> <h4 class="wp-block-heading">9. Zulassung des Medikaments</h4> <p>Die Ergebnisse der durchgeführten Studien, der Labor- und Tierversuche sowie derjenigen aus technischen Qualitätstests werden von Fachleuten der jeweiligen Zulassungsbehörde geprüft. Bei positiver Bewertung dieser Daten für die Patient:innen kann es zu einer Zulassung des Medikaments für eine bestimmte Erkrankung kommen. Erst wenn ein Medikament zugelassen ist, kann es auf den Markt gebracht werden.</p> </div> <div class="wp-block-column is-layout-flow"><div class="wp-block-image"> <figure class="aligncenter size-large is-resized"><img decoding="async" loading="lazy" src="https://www.msd.de/wp-content/uploads/sites/33/2021/10/rocking-horse.png?w=291" alt="icon with horse" class="wp-image-9741" width="146" height="143"/></figure></div> <h4 class="wp-block-heading">10. Festlegung eines möglichen Kinderstudienplans</h4> <p>Die Zulassungsbehörde legt fest, ob das Medikament für Kinder oder besondere Patientengruppen wie zum Beispiel Schwangere zusätzlich erprobt werden soll. Kinderstudien beginnen in der Regel erst nach Zulassung des Arzneimittels für Erwachsene, manchmal aber auch zeitgleich.</p> </div> </div> <div class="wp-block-columns is-layout-flex wp-container-20"> <div class="wp-block-column is-layout-flow"><div class="wp-block-image"> <figure class="aligncenter size-large is-resized"><img decoding="async" loading="lazy" src="https://www.msd.de/wp-content/uploads/sites/33/2021/10/medicines_blue.png?w=286" alt="icon with medicamentes" class="wp-image-9740" width="143" height="143"/></figure></div> <h4 class="wp-block-heading">11. Entwicklung zusätzlicher Darreichungsformen</h4> <p>Bei Bedarf können noch zusätzliche Darreichungsformen entwickelt werden, zum Beispiel eine Tablette oder Injektionslösung.<br></p> </div> <div class="wp-block-column is-layout-flow"><div class="wp-block-image"> <figure class="aligncenter size-large is-resized"><img decoding="async" loading="lazy" src="https://www.msd.de/wp-content/uploads/sites/33/2021/10/bar-chart.png?w=291" alt="icon with graph" class="wp-image-9743" width="146" height="143"/></figure></div> <h4 class="wp-block-heading">12. Weitere Beobachtung und mögliche Phase IV Studien</h4> <p>Ärzt:innen, Behörden und Hersteller überwachen das Medikament nach erfolgter Zulassung. In möglichen Phase-IV-Studien wird der Einsatz unter realen Bedingungen erforscht, u.a. zur Beobachtung, wie es mit anderen Arzneimitteln zusammenwirkt oder ob es auch für weitere Krankheiten in Betracht gezogen werden könnte.</p> </div> </div> </div></div> <div style="height:100px" aria-hidden="true" class="wp-block-spacer"></div> <div class="text-hero-block mccberg-block"> <div class="breadcrumbs wrapper text-descriptive"><span><span><a href="https://www.msd.de/forschung-und-arzneimittel/">Forschung und Arzneimittel</a></span> > <span class="breadcrumb_last" aria-current="page">Hintergrundwissen</span></span></div> <h1>Das MSD Portal für klinische Studien</h1> <p>Auf unserem Studienportal finden Sie Kurzinformationen zu den einzelnen klinischen Studien von MSD, in die Patient:innen aufgenommen werden. Wenn Sie an einer Studienteilnahme interessiert sind, sprechen Sie bitte mit Ihrer behandelnden Ärztin bzw. Ihrem behandelnden Arzt, bevor Sie in Kontakt mit einem der beteiligten Studienzentren treten. Ihre Ärztin bzw. Ihr Arzt wird mit Ihnen eine erste Einschätzung vornehmen können, ob eine klinische Studie für Ihre Erkrankung infrage kommen könnte.</p> <a class="btn" href="https://www.msd.de/forschung-und-arzneimittel/klinische-studien/" title="Klinische Studien von MSD in Deutschland" target="_blank">Klinische Studien von MSD in Deutschland</a> </div> <div style="height:100px" aria-hidden="true" class="wp-block-spacer"></div> <div id="mco-title-block-block_1d779c86ae829eb1e762711550bb971e" class="mco-title-block mccberg-block pull-up-stats negative no-mt mb-2 aligncenter" > <div class="wrapper"> <div class="mco-title-block-content"> <h2 class="mco-title-block-title">Arzneimittel-Entwicklung in Zahlen</h2> </div> </div> </div> <div class="wp-block-group is-layout-flow"><div class="wp-block-group__inner-container"><div id="stat-block-block_87ab99222ed91bb83166e0bbda5614c2" class="stat-block mccberg-block"> <div class="stat-block-content "> <div class="stat-block-statistic">13 Jahre</div> <div class="stat-block-tablet-wrapper"> <p class="stat-block-description">vergehen durchschnittlich von der Idee bis zum zugelassenen Medikament.</p> </div> </div> </div> <div id="stat-block-block_bd614af762dbc8be21ff1c961996ac58" class="stat-block mccberg-block"> <div class="stat-block-content "> <div class="stat-block-statistic">1-1,6Mrd</div> <div class="stat-block-tablet-wrapper"> <p class="stat-block-description">US-Dollar Budget müssen forschende Arzneimittelhersteller für jedes neue Medikament einplanen.</p> </div> </div> </div> <div id="stat-block-block_9fc0a437d247322df7bca035bb4acf42" class="stat-block mccberg-block"> <div class="stat-block-content "> <div class="stat-block-statistic">5-10Tsd</div> <div class="stat-block-tablet-wrapper"> <p class="stat-block-description">Substanzen werden untersucht bis 1 Medikament zugelassen wird.</p> </div> </div> </div></div></div> </div> </article> </main> </div> </div> <div class="related-content-container" id="related-content-main"> <h2>Weiterführende Links</h2> <div class="related-content-section"> <div class="related-content-item"> <a href="https://www.msd.de/politik-und-verantwortung/transparenz-bei-msd/" target="" title="Transparenz bei MSD"> <div class="related-content-item-image-contianer"> <picture> <source media="(max-width: 767px)" srcset="https://www.msd.de/wp-content/uploads/sites/33/2021/10/17374243_Besprechung_im_Buero_2048x1365px.jpg?resize=321,196"> <source media="(min-width: 768px) and (max-width: 1279px)" srcset="https://www.msd.de/wp-content/uploads/sites/33/2021/10/17374243_Besprechung_im_Buero_2048x1365px.jpg?resize=314,280"> <source media="(min-width: 1280px)" srcset="https://www.msd.de/wp-content/uploads/sites/33/2021/10/17374243_Besprechung_im_Buero_2048x1365px.jpg?resize=404,268"> <img class="lazyload" loading="lazy" data-src="https://www.msd.de/wp-content/uploads/sites/33/2021/10/17374243_Besprechung_im_Buero_2048x1365px.jpg?resize=404,268" alt="related content image #1"> </picture> </div> <div class="related-content-content-container"> <p><strong>Transparenz bei MSD</strong></p> <p class="realted-content-excerpt">Volle Transparenz – Wir bei MSD sind stolz auf das, was wir tun und für wen wir etwas tun. Diese Informationen teilen wir gerne.</p> </div> </a> </div> <div class="related-content-item"> <a href="https://www.msd.de/forschung-und-arzneimittel/klinische-studien/" target="" title="Klinische Studien von MSD"> <div class="related-content-item-image-contianer"> <picture> <source media="(max-width: 767px)" srcset="https://www.msd.de/wp-content/uploads/sites/33/2022/05/Bild_Digital-Archives_Getty-Images_106002250_22_Teal_65x43-1.png?resize=321,196"> <source media="(min-width: 768px) and (max-width: 1279px)" srcset="https://www.msd.de/wp-content/uploads/sites/33/2022/05/Bild_Digital-Archives_Getty-Images_106002250_22_Teal_65x43-1.png?resize=314,280"> <source media="(min-width: 1280px)" srcset="https://www.msd.de/wp-content/uploads/sites/33/2022/05/Bild_Digital-Archives_Getty-Images_106002250_22_Teal_65x43-1.png?resize=404,268"> <img class="lazyload" loading="lazy" data-src="https://www.msd.de/wp-content/uploads/sites/33/2022/05/Bild_Digital-Archives_Getty-Images_106002250_22_Teal_65x43-1.png?resize=404,268" alt="related content image #2"> </picture> </div> <div class="related-content-content-container"> <p><strong>Klinische Studien von MSD</strong></p> <p class="realted-content-excerpt">MSD führt kontinuierlich klinische Studien durch, für die Patient:innen rekrutiert werden.</p> </div> </a> </div> <div class="related-content-item"> <a href="https://www.msd.de/?page_id=40" target="" title="Unsere Partnerschaften"> <div class="related-content-item-image-contianer"> <picture> <source media="(max-width: 767px)" srcset="https://www.msd.de/wp-content/uploads/sites/33/2021/10/17374316_Labor_Arzt_2048x1365px.jpg?resize=321,196"> <source media="(min-width: 768px) and (max-width: 1279px)" srcset="https://www.msd.de/wp-content/uploads/sites/33/2021/10/17374316_Labor_Arzt_2048x1365px.jpg?resize=314,280"> <source media="(min-width: 1280px)" srcset="https://www.msd.de/wp-content/uploads/sites/33/2021/10/17374316_Labor_Arzt_2048x1365px.jpg?resize=404,268"> <img class="lazyload" loading="lazy" data-src="https://www.msd.de/wp-content/uploads/sites/33/2021/10/17374316_Labor_Arzt_2048x1365px.jpg?resize=404,268" alt="related content image #3"> </picture> </div> <div class="related-content-content-container"> <p><strong>Unsere Partnerschaften</strong></p> <p class="realted-content-excerpt">MSD pflegt den Austausch mit Wissenschaftler:innen, Patient:innen und Patientenvertreter:innen sowie Vertreter:innen aus Politik und anderen Pharmaunternehmen.</p> </div> </a> </div> </div> </div> <footer id="footerMain" class="footer"> <div id="footerSocial"> <div class="wrapper"> <h3>Folgen Sie uns auf Social Media! </h3> <div class="social-icons"> <a href="https://www.linkedin.com/company/msd-deutschland" target="_blank"> <img class="lazyload" loading="lazy" data-src="https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/images/linkedin-brands.svg" alt="Linkedin icon" /> </a> <a href="https://www.instagram.com/msd_deutschland/" target="_blank"> <img class="lazyload" loading="lazy" data-src="https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/images/instagram-brands.svg" alt="Instagram icon" /> </a> <a href="https://www.youtube.com/user/MsdDeutschland" target="_blank"> <img class="lazyload" loading="lazy" data-src="https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/images/youtube-brands.svg" alt="YouTube icon" /> </a> </div> </div> </div> <div class="wrapper"> <div id="footerPrograms"> <div class="column col-one"> <input type="checkbox" name ="one" id="columnOne" class="checkbox-toggle"> <label for="columnOne" class="column-header">Für Patient:innen und Fachkreiseportal</label> <ul> <li> <a href="https://www.msdmanuals.com/de" target="_blank" rel="noopener">MSD Manuals</a> <br /> Medizinische Informationsquelle mit tausenden Themen aus allen Bereichen der Medizin </li> <li> <a href="https://www.msd-gesundheit.de/" target="_blank" rel="noopener">MSD Patientenportal</a> <br /> MSD Gesundheit – unser Patientenportal mit umfangreichen Informationen zu Gesundheit und Krankheit </li> <li> <a href="https://www.msdconnect.de/" target="_blank" rel="noopener">MSD Fachkreiseportal</a> <br /> MSD Connect ist unser Fachkreiseportal mit wissenschaftlichen Informationen zu unseren Medikamenten und Impfstoffen </li> </ul> </div> <div class="column col-two"> <input type="checkbox" name ="two" id="columnTwo" class="checkbox-toggle"> <label for="columnTwo" class="column-header"> </label> <ul> <li> <a href="https://www.msd-tiergesundheit.de/" target="_blank" rel="noopener">MSD Tiergesundheit</a> <br /> Innovative, hochwertige Tiergesundheitsprodukte – zur Homepage der Tierarzneisparte MSD </li> <li> <a href="https://care.msdconnect.de/" target="_blank" rel="noopener">MSD Care</a> <br /> Wissenswertes und Nützliches für nicht-ärztliches Fachpersonal </li> </ul> </div> <div class="column col-three"> <input type="checkbox" name ="three" id="columnThree" class="checkbox-toggle"> <label for="columnThree" class="column-header">Ihr Kontakt zu uns</label> <ul> <li> <a href="https://www.msd.de/kontakt/" target="_blank" rel="noopener">Haben Sie noch Fragen?</a> <br /> Kontaktieren Sie uns über den Kanal Ihrer Wahl – unsere Teams helfen Ihnen gerne weiter! Neben offiziellen Kontaktmöglichkeiten finden Sie dort auch themenspezifische FAQs. </li> </ul> </div> </div> <div id="footerCopyrightLogos"> <div id="footerCopyright"> <div class="menu-footer-container"><ul id="menuFooter" class="footer-links"><li id="menu-item-10429" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-10429"><a href="https://www.msd.de/kontakt/">Kontakt</a></li><li id="menu-item-10430" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-10430"><a href="https://www.msd.de/impressum/">Impressum</a></li><li id="menu-item-10431" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-10431"><a href="https://www.msd.de/datenschutz/">Datenschutz</a></li><li id="menu-item-12123" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-12123"><a href="https://www.msd.de/agb/">AGB</a></li><li id="menu-item-17155" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-17155"><a href="https://www.msd.de/unsere-verpflichtung-zu-barrierefreiheit/">Barrierefreiheit</a></li><li id="menu-item-27036" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-27036"><a href="https://www.msd.de/lksg-informations-und-kontaktseite/">Lieferkettengesetz</a></li><li id="menu-item-746" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-746"><a target="_blank" rel="noopener" href="https://www.msdprivacy.com/">Cookie policy</a></li><li class="menu-item"><button id="menu-item-6038" class="ot-sdk-show-settings menu-item menu-item-type-custom menu-item-object-custom menu-item-6038"><a href="#">Cookiepräferenzen</a></button></li></ul></div> <small> Copyright © 2024 Merck & Co., Inc., Rahway, NJ, USA and its affiliates. All rights reserved. </small> </div> <div id="footerLogos"> <div id="footerLogosTrusteBadges"> <a href="https://www.essentialaccessibility.com/msd" target="_blank" rel="noopener" class="accessibility"> <img class="lazyload" loading="lazy" data-src="https://www.msd.de/accessibility/" alt="Accessibility icon" data-design-category="accessibility_icon" /> </a> </div> </div> </div> </div> </footer> <div id="fowardGuidanceModel" class="popup" style="display: none;"> <div class="popup-wrapper"> <div class="popup-content foward-guide-modal-content"> <h3>Forward-looking statement of Merck & Co., Inc., Rahway, N.J., USA</h3> <div class="forward-guidance-content"> <p> This news release of Merck & Co., Inc., Rahway, N.J., USA (the “company”) includes “forward-looking statements” within the meaning of the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995. These statements are based upon the current beliefs and expectations of the company’s management and are subject to significant risks and uncertainties. There can be no guarantees with respect to pipeline products that the products will receive the necessary regulatory approvals or that they will prove to be commercially successful. If underlying assumptions prove inaccurate or risks or uncertainties materialize, actual results may differ materially from those set forth in the forward-looking statements. <br /><br /> Risks and uncertainties include but are not limited to, general industry conditions and competition; general economic factors, including interest rate and currency exchange rate fluctuations; the impact of the recent global outbreak of novel coronavirus disease (COVID-19); the impact of pharmaceutical industry regulation and health care legislation in the United States and internationally; global trends toward health care cost containment; technological advances, new products and patents attained by competitors; challenges inherent in new product development, including obtaining regulatory approval; the company’s ability to accurately predict future market conditions; manufacturing difficulties or delays; financial instability of international economies and sovereign risk; dependence on the effectiveness of the company’s patents and other protections for innovative products; and the exposure to litigation, including patent litigation, and/or regulatory actions. <br /><br /> The company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise. Additional factors that could cause results to differ materially from those described in the forward-looking statements can be found in the company’s 2020 Annual Report on Form 10-K and the company’s other filings with the Securities and Exchange Commission (SEC) available at the SEC’s Internet site (<a href="https://www.sec.gov/" target="_blank">www.sec.gov</a>). <br /><br /> <strong>No Duty to Update</strong> <br /><br /> The information contained in this website was current as of the date presented. The company assumes no duty to update the information to reflect subsequent developments. Consequently, the company will not update the information contained in the website and investors should not rely upon the information as current or accurate after the presentation date. </p> </div> <div class="btn-container text-center"> <a href="https://www.msd.de/" class="btn tertiary">Decline</a> <a href="javascript:void()" class="btn tertiary negative" title="" onclick="sessionStorage.setItem('guidance-accepted', JSON.stringify(true)); document.getElementById('fowardGuidanceModel').style.display = 'none';">Accept</a> </div> </div> </div> </div> <script> utag_data.page_datepublished = "2020-11-08 23:53:08"; utag_data.page_datemodified = "2023-11-24 11:01:02"; dataLayer.push(utag_data); </script> <script type="text/javascript"> /* * FileSaver.js * A saveAs() FileSaver implementation. * * By Eli Grey, http://eligrey.com * * License : https://github.com/eligrey/FileSaver.js/blob/master/LICENSE.md (MIT) * source : http://purl.eligrey.com/github/FileSaver.js */ // The one and only way of getting global scope in all environments // https://stackoverflow.com/q/3277182/1008999 var _global = typeof window === 'object' && window.window === window ? window : typeof self === 'object' && self.self === self ? self : typeof global === 'object' && global.global === global ? global : this function bom (blob, opts) { if (typeof opts === 'undefined') opts = { autoBom: false } else if (typeof opts !== 'object') { console.warn('Deprecated: Expected third argument to be a object') opts = { autoBom: !opts } } // prepend BOM for UTF-8 XML and text/* types (including HTML) // note: your browser will automatically convert UTF-16 U+FEFF to EF BB BF if (opts.autoBom && /^\s*(?:text\/\S*|application\/xml|\S*\/\S*\+xml)\s*;.*charset\s*=\s*utf-8/i.test(blob.type)) { return new Blob([String.fromCharCode(0xFEFF), blob], { type: blob.type }) } return blob } function download (url, name, opts) { var xhr = new XMLHttpRequest() xhr.open('GET', url) xhr.responseType = 'blob' xhr.onload = function () { saveAs(xhr.response, name, opts) } xhr.onerror = function () { console.error('could not download file') } xhr.send() } function corsEnabled (url) { var xhr = new XMLHttpRequest() // use sync to avoid popup blocker xhr.open('HEAD', url, false) try { xhr.send() } catch (e) {} return xhr.status >= 200 && xhr.status <= 299 } // `a.click()` doesn't work for all browsers (#465) function click (node) { try { node.dispatchEvent(new MouseEvent('click')) } catch (e) { var evt = document.createEvent('MouseEvents') evt.initMouseEvent('click', true, true, window, 0, 0, 0, 80, 20, false, false, false, false, 0, null) node.dispatchEvent(evt) } } // Detect WebView inside a native macOS app by ruling out all browsers // We just need to check for 'Safari' because all other browsers (besides Firefox) include that too // https://www.whatismybrowser.com/guides/the-latest-user-agent/macos var isMacOSWebView = /Macintosh/.test(navigator.userAgent) && /AppleWebKit/.test(navigator.userAgent) && !/Safari/.test(navigator.userAgent) var saveAs = _global.saveAs || ( // probably in some web worker (typeof window !== 'object' || window !== _global) ? function saveAs () { /* noop */ } // Use download attribute first if possible (#193 Lumia mobile) unless this is a macOS WebView : ('download' in HTMLAnchorElement.prototype && !isMacOSWebView) ? function saveAs (blob, name, opts) { var URL = _global.URL || _global.webkitURL var a = document.createElement('a') name = name || blob.name || 'download' a.download = name a.rel = 'noopener' // tabnabbing // TODO: detect chrome extensions & packaged apps // a.target = '_blank' if (typeof blob === 'string') { // Support regular links a.href = blob if (a.origin !== location.origin) { corsEnabled(a.href) ? download(blob, name, opts) : click(a, a.target = '_blank') } else { click(a) } } else { // Support blobs a.href = URL.createObjectURL(blob) setTimeout(function () { URL.revokeObjectURL(a.href) }, 4E4) // 40s setTimeout(function () { click(a) }, 0) } } // Use msSaveOrOpenBlob as a second approach : 'msSaveOrOpenBlob' in navigator ? function saveAs (blob, name, opts) { name = name || blob.name || 'download' if (typeof blob === 'string') { if (corsEnabled(blob)) { download(blob, name, opts) } else { var a = document.createElement('a') a.href = blob a.target = '_blank' setTimeout(function () { click(a) }) } } else { navigator.msSaveOrOpenBlob(bom(blob, opts), name) } } // Fallback to using FileReader and a popup : function saveAs (blob, name, opts, popup) { // Open a popup immediately do go around popup blocker // Mostly only available on user interaction and the fileReader is async so... popup = popup || open('', '_blank') if (popup) { popup.document.title = popup.document.body.innerText = 'downloading...' } if (typeof blob === 'string') return download(blob, name, opts) var force = blob.type === 'application/octet-stream' var isSafari = /constructor/i.test(_global.HTMLElement) || _global.safari var isChromeIOS = /CriOS\/[\d]+/.test(navigator.userAgent) if ((isChromeIOS || (force && isSafari) || isMacOSWebView) && typeof FileReader !== 'undefined') { // Safari doesn't allow downloading of blob URLs var reader = new FileReader() reader.onloadend = function () { var url = reader.result url = isChromeIOS ? url : url.replace(/^data:[^;]*;/, 'data:attachment/file;') if (popup) popup.location.href = url else location = url popup = null // reverse-tabnabbing #460 } reader.readAsDataURL(blob) } else { var URL = _global.URL || _global.webkitURL var url = URL.createObjectURL(blob) if (popup) popup.location = url else location.href = url popup = null // reverse-tabnabbing #460 setTimeout(function () { URL.revokeObjectURL(url) }, 4E4) // 40s } } ) _global.saveAs = saveAs.saveAs = saveAs if (typeof module !== 'undefined') { module.exports = saveAs; } /*! ics.js Wed Sept 14 2017 */ var ics=function(e,t){"use strict";{if(!(navigator.userAgent.indexOf("MSIE")>-1&&-1==navigator.userAgent.indexOf("MSIE 10"))){void 0===e&&(e="default"),void 0===t&&(t="Calendar");var r=-1!==navigator.appVersion.indexOf("Win")?"\r\n":"\n",n=[],i=["BEGIN:VCALENDAR","PRODID:"+t,"VERSION:2.0"].join(r),o=r+"END:VCALENDAR",a=["SU","MO","TU","WE","TH","FR","SA"];return{events:function(){return n},calendar:function(){return i+r+n.join(r)+o},addEvent:function(t,i,o,l,u,s){if(void 0===t||void 0===i||void 0===o||void 0===l||void 0===u)return!1;if(s&&!s.rrule){if("YEARLY"!==s.freq&&"MONTHLY"!==s.freq&&"WEEKLY"!==s.freq&&"DAILY"!==s.freq)throw"Recurrence rrule frequency must be provided and be one of the following: 'YEARLY', 'MONTHLY', 'WEEKLY', or 'DAILY'";if(s.until&&isNaN(Date.parse(s.until)))throw"Recurrence rrule 'until' must be a valid date string";if(s.interval&&isNaN(parseInt(s.interval)))throw"Recurrence rrule 'interval' must be an integer";if(s.count&&isNaN(parseInt(s.count)))throw"Recurrence rrule 'count' must be an integer";if(void 0!==s.byday){if("[object Array]"!==Object.prototype.toString.call(s.byday))throw"Recurrence rrule 'byday' must be an array";if(s.byday.length>7)throw"Recurrence rrule 'byday' array must not be longer than the 7 days in a week";s.byday=s.byday.filter(function(e,t){return s.byday.indexOf(e)==t});for(var c in s.byday)if(a.indexOf(s.byday[c])<0)throw"Recurrence rrule 'byday' values must include only the following: 'SU', 'MO', 'TU', 'WE', 'TH', 'FR', 'SA'"}}var g=new Date(l),d=new Date(u),f=new Date,S=("0000"+g.getFullYear().toString()).slice(-4),E=("00"+(g.getMonth()+1).toString()).slice(-2),v=("00"+g.getDate().toString()).slice(-2),y=("00"+g.getHours().toString()).slice(-2),A=("00"+g.getMinutes().toString()).slice(-2),T=("00"+g.getSeconds().toString()).slice(-2),b=("0000"+d.getFullYear().toString()).slice(-4),D=("00"+(d.getMonth()+1).toString()).slice(-2),N=("00"+d.getDate().toString()).slice(-2),h=("00"+d.getHours().toString()).slice(-2),I=("00"+d.getMinutes().toString()).slice(-2),R=("00"+d.getMinutes().toString()).slice(-2),M=("0000"+f.getFullYear().toString()).slice(-4),w=("00"+(f.getMonth()+1).toString()).slice(-2),L=("00"+f.getDate().toString()).slice(-2),O=("00"+f.getHours().toString()).slice(-2),p=("00"+f.getMinutes().toString()).slice(-2),Y=("00"+f.getMinutes().toString()).slice(-2),U="",V="";y+A+T+h+I+R!=0&&(U="T"+y+A+T,V="T"+h+I+R);var B,C=S+E+v+U,j=b+D+N+V,m=M+w+L+("T"+O+p+Y);if(s)if(s.rrule)B=s.rrule;else{if(B="rrule:FREQ="+s.freq,s.until){var x=new Date(Date.parse(s.until)).toISOString();B+=";UNTIL="+x.substring(0,x.length-13).replace(/[-]/g,"")+"000000Z"}s.interval&&(B+=";INTERVAL="+s.interval),s.count&&(B+=";COUNT="+s.count),s.byday&&s.byday.length>0&&(B+=";BYDAY="+s.byday.join(","))}(new Date).toISOString();var H=["BEGIN:VEVENT","UID:"+n.length+"@"+e,"CLASS:PUBLIC","DESCRIPTION:"+i,"DTSTAMP;VALUE=DATE-TIME:"+m,"DTSTART;VALUE=DATE-TIME:"+C,"DTEND;VALUE=DATE-TIME:"+j,"LOCATION:"+o,"SUMMARY;LANGUAGE=en-us:"+t,"TRANSP:TRANSPARENT","END:VEVENT"];return B&&H.splice(4,0,B),H=H.join(r),n.push(H),H},download:function(e,t){if(n.length<1)return!1;t=void 0!==t?t:".ics",e=void 0!==e?e:"calendar";var a,l=i+r+n.join(r)+o;if(-1===navigator.userAgent.indexOf("MSIE 10"))a=new Blob([l]);else{var u=new BlobBuilder;u.append(l),a=u.getBlob("text/x-vCalendar;charset="+document.characterSet)}return saveAs(a,e+t),l},build:function(){return!(n.length<1)&&i+r+n.join(r)+o}}}console.log("Unsupported Browser")}}; function GenerateICS(title, description, start, end) { let cal = new ics(); cal.addEvent(decodeURIComponent(title), decodeURIComponent(description), "", start, end); cal.download(decodeURIComponent(title)); } </script></div>  <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-MZG3KZL" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript>  <link rel='stylesheet' id='search-form-style-css' href='https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/css/search-form.min.css?ver=20201010' media='all' /> <link rel='stylesheet' id='mco-hero-block-css-css' href='https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/blocks/mccberg/hero-block/css/style.css?ver=1732907425' media='all' /> <link rel='stylesheet' id='mco-text-hero-block-css-css' href='https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/blocks/mccberg/text-hero-block/css/style.css?ver=6.2.6' media='all' /> <link rel='stylesheet' id='mco-title-block-css-css' href='https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/blocks/mccberg/title-block/css/style.css?ver=6.2.6' media='all' /> <link rel='stylesheet' id='stat-block-css-css' href='https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/blocks/mccberg/statistics-content/css/style.css?ver=6.2.6' media='all' /> <link rel='stylesheet' id='related-content-styles-css' href='https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/css/related-content-section.min.css?ver=6.2.6' media='all' /> <style id='core-block-supports-inline-css'> .wp-container-3.wp-container-3,.wp-container-6.wp-container-6,.wp-container-10.wp-container-10,.wp-container-13.wp-container-13,.wp-container-17.wp-container-17,.wp-container-20.wp-container-20{flex-wrap:nowrap;} </style> <script defer="defer" src='https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/js/plugins.min.js?ver=1724751470' id='MCC-plugins-js'></script> <script id='MCC-scripts-js-extra'> var MCC_scripts_vars = {"format":["d",".","m",".","Y"]}; </script> <script defer="defer" src='https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/js/scripts.min.js?ver=1732907425' id='MCC-scripts-js'></script> <script defer="defer" src='https://unpkg.com/micromodal/dist/micromodal.min.js?ver=6.2.6' id='tiny-modal-js-js'></script> <script defer="defer" src='https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/blocks/mccberg/hero-block/js/index.js?ver=6.2.6' id='hero-modal-block-js-js'></script> <script defer="defer" src='https://www.msd.de/wp-content/themes/cex-wpvip-mhh-mhh2-mcc-theme/blocks/mccberg/statistics-content/js/index.js?ver=6.2.6' id='stat-block-js-js'></script> <div id="externalLinkModal" class="popup" style="display: none;"> <div class="popup-wrapper"> <div class="popup-content forward-guide-modal-content"> <h3 id="externalLinkModalTitle"></h3> <div class="forward-guidance-content"> <p id="externalLinkModalMessage" style="max-width: 31.25rem;"></p> </div> <div class="btn-container text-center"> <button class="btn tertiary" id="externalLinkCancelBtn" title="" onclick="closeExternalLinkModal()"></button> <a href="#" target="_blank" class="btn tertiary negative" id="externalLinkModalBtn" onclick="closeExternalLinkModal()"></a> </div> </div> </div> </div> <script> var documentLinks = [].slice.call(document.links); var allowedDomains = (["\/mcc",".local\/mcc","-develop.go-vip.net\/mcc","-preprod.go-vip.net\/mcc","vip2-msd.com\/mcc","q4cdn.com","cloudfront.net","wpvip-safety-data-sheets.s3.amazonaws.com","google.com\/calendar","outlook.live.com\/calendar","calendar.yahoo.com","msdresponsibility.com","localhost","msdlicensing.com","mailto","care.msdconnect.de","jobs.msd.com","gesundheitsforum.msd.de","msd.wd5.myworkdayjobs.com\/SearchJobs\/logi","m.msd.de","www.msdconnect.de","www.msdprivacy.com","www.cafekrebs.de","www.entschiedengegenkrebs.de","www.msd-gesundheitspreis.de","www.msd-gesundheit.de","www.msd-immunonkologie.de","www.msd-information.de","msdconnect.de","msdprivacy.com","cafekrebs.de","entschiedengegenkrebs.de","msd-gesundheitspreis.de","msd-gesundheit.de","msd-immunonkologie.de","public-disclosure.msd.com","www.msdmanuals.com","msdmanuals.com","msd-tiergesundheit.de","www.msd-tiergesundheit.de","www.msdclinicaltrials.com","msdclinicaltrials.com","msd.com","www.msd.com","msdcustomerlink.de","www.msdghifund.com","msdghifund.com","www.msdmedicalportal.de","msdmedicalportal.de","www.msdcustomerlink.de","msdcustomerlink.de","www.patienteninfo-service.de","www.fachinfo.de"] || []).filter(function(domain) { let documentDomain = stripHttpsWWW(document.location.hostname); return stripHttpsWWW(domain) !== documentDomain && Boolean(domain); }); var configuredExternalLinks = ([{"title":"Sie verlassen jetzt MSD.de","message":"Der Link, den Sie ausgew\u00e4hlt haben, f\u00fchrt Sie zu einer Website au\u00dferhalb von www.msd.de. Die dort zur Verf\u00fcgung gestellten aktuellen Meldungen verweisen auf unabh\u00e4ngige Informationsquellen und stellen nicht notwendigerweise die Meinung von MSD dar. Wir sind MSD Sharp & Dohme GmbH mit Firmensitz in M\u00fcnchen, Deutschland.","cancelBtnText":"Abbrechen","continueBtnText":"Weiter","domains":["*"]},{"title":"Sie verlassen jetzt MSD.de","message":"Der Link, den Sie ausgew\u00e4hlt haben, f\u00fchrt Sie zu einer Website au\u00dferhalb von www.msd.de. Wir sind MSD Sharp & Dohme GmbH mit Firmensitz in M\u00fcnchen, Deutschland.","cancelBtnText":"Abbrechen","continueBtnText":"Weiter","domains":["msd-australia.com.au","msd.co.il","msd.co.jp","msd.co.za","msd.com.ar","msd.com.tr","msd.com.tw","msd.com.ve","msdchina.com.cn","msdonline.com.br","msd.com.hk","www.msd-tiergesundheit.de","www.merck.com","www.msd.com","www.merck.ca","www.msd.pt","www.msd.rs","www.msd-belgium.be","www.msd-bulgaria.com","www.msd-egypt.com","www.msd-indonesia.com","www.msd-ireland.com","www.msd-italia.it","www.msd-korea.com","www.msd-malaysia.com","www.msd-saudi.com","www.msd-singapore.com","www.msd-thailand.com","www.msd-vietnam.com","www.msd.at","www.msd.dk","www.msd.ee","www.msd.es","www.msd.fi","www.msd.gr","www.msd.hr","www.msd.hu","www.msd.lt","www.msd.lv","www.msd.nl","www.msd.no","www.msd.ru","www.msd.se","www.msd.si","www.msd.sk","www.msd.ua","www.msdindia.in","www.msd-middleeast.com","www.msd-newzealand.com","www.msd-uk.com","www.msd.ch","www.msd.cz","www.msd.pl","www.msd.ro","www.msd-france.com","msd.com"]}] || []); if (typeof Array.prototype.some !== 'function') { Array.prototype.some = function(predicate, thisArg) { if (typeof predicate !== 'function') { throw TypeError('Array.prototype.some(): predicate must be a function.'); } for (var i = 0; i < this.length; i++) { if (predicate.call(thisArg, this[i], i, this)) { return true; } } return false; }; } for (var i = 0; i < documentLinks.length; i++) { var link = documentLinks[i]; if (shouldAllowDomain(link.href)) { continue; } link.addEventListener('click', function(e) { e.preventDefault(); var modalData = getExternalLinkContent(this.href); if (!modalData) { var win = window.open(this.href, this.target); if (win) { win.focus(); } return; } var modal = document.getElementById('externalLinkModal'); var modalTitle = document.getElementById('externalLinkModalTitle'); var modalCancelBtn = document.getElementById('externalLinkCancelBtn'); var modalMessage = document.getElementById('externalLinkModalMessage'); var modalContinueLink = document.getElementById('externalLinkModalBtn'); if (modalTitle) { modalTitle.textContent = modalData.title; } if (modalMessage) { modalMessage.textContent = modalData.message; } if (modalCancelBtn) { modalCancelBtn.textContent = modalData.cancelBtnText || 'Cancel'; } if (modalContinueLink) { modalContinueLink.href = this.href; modalContinueLink.textContent = modalData.continueBtnText || 'Proceed'; } if (modal) { modal.style.display = modal.style.display === 'none' ? 'block' : 'none'; } }); } function getExternalLinkContent(link) { var wildCardLinks = []; for (var i = 0; i < configuredExternalLinks.length; i++) { var configuredExternalLink = configuredExternalLinks[i]; for (var j = 0; j < configuredExternalLink.domains.length; j++) { var domain = configuredExternalLink.domains[j]; if (domain === '*') { wildCardLinks.push(configuredExternalLink); } if (link.indexOf(domain) !== -1) { return configuredExternalLink; } } } if (!wildCardLinks.length) { return null; } return wildCardLinks[0]; } function stripHttpsWWW(link){ let cleanLink = link.replace(/http(s)?:\/\//g, ''); let cleanWithoutWWW = cleanLink.replace(/(www\.)?/g, ''); return cleanWithoutWWW; } function shouldAllowDomain(link) { //get the domain text without the http or https or www. var urlParts = stripHttpsWWW(link).split('/'); if (!urlParts.length) { return false; } var domain = urlParts[0]; if (domain === stripHttpsWWW(document.location.hostname)) { return true; } if (isSubdomain(domain)) { return allowedDomains.indexOf(domain) !== -1; } return allowedDomains.some(function(whiteListedDomain) { whiteListedDomain = stripHttpsWWW(whiteListedDomain); var domainRegex = new RegExp(whiteListedDomain); return domainRegex.test(domain); }); } function isSubdomain(domain) { return domain.split('.').length === 2 ? false : true; } function closeExternalLinkModal() { var modal = document.getElementById('externalLinkModal'); if (modal) { modal.style.display = 'none'; } } </script> <div id="ukUserModal" class="popup" style="display: none;"> <div class="popup-wrapper"> <div class="popup-content foward-guide-modal-content"> <h3></h3> <div class="forward-guidance-content"> <p style="max-width: 31.25rem;"></p> </div> <div class="btn-container text-center"> <a target="_blank" class="btn tertiary negative" id="externalLinkModalBtn" onclick="AcceptUKMessage();"> </a> </div> </div> </div> </div> <script type="text/javascript"> function AcceptUKMessage() { try { let accepted = { expire: new Date(new Date().getTime() + 60 * 60 * 24 * 1000) }; sessionStorage.setItem('uk-messaging', JSON.stringify(accepted)); document.getElementById('ukUserModal').style.display = 'none'; } catch (ex) { console.log(ex); } } </script> <script> removeTopBorderFromSeparatorBlock(); function removeTopBorderFromSeparatorBlock() { let separatorBlock = document.querySelectorAll('.wp-block-separator.is-style-wide'); for (let i = 0; i < separatorBlock.length; i++) { separatorBlock[i].style.borderTop = '0px'; } } // Set the offset when entering page with hash present in the url document.addEventListener('DOMContentLoaded', (e) => { if (location.hash.length !== 0) { accordionFocus(); } function accordionFocus() { const URL = window.location.href; const splittedURL = URL.split('/'); //accordion id should be at the end const possibleAccordionID = splittedURL[splittedURL.length - 1]; const RegExp = /#[a-zA-Z-\d]+/gi; const foundAccordionMatch = RegExp.test(possibleAccordionID); //Check if param was found if (foundAccordionMatch) { setTimeout(function() { let accordionName = possibleAccordionID.match(RegExp).toString(); const accordionId = accordionName.replace('#', ''); let accordionControl = document.getElementById(accordionId); if (accordionControl && accordionControl.closest('.b6-accordion-list-item-details')) { allA6Tabs = document.querySelectorAll('.mccberg-tab-content'); if(allA6Tabs.length > 0){ openA6tab(allA6Tabs, accordionControl) } //get the element closest to the collapse handle let accordionDetail = accordionControl.closest('.b6-accordion-list-item-details') accordionDetail.setAttribute('open', " "); accordionDetail.scrollIntoView(); } }, 500); } } }); function openA6tab(allA6Tabs, accordionControl) { //close all A6tabs and Title allA6TabsTitle = document.querySelectorAll('.mccberg-tab-title'); for (let i = 0; i < allA6Tabs.length; i++) { allA6Tabs[i].classList.remove('open'); allA6TabsTitle[i].classList.remove('open'); } let accordionDetailA6 = accordionControl.closest('.mccberg-tab-content') // Assuming accordionDetailA6 is the element you are working with let matchedClass = Array.from(accordionDetailA6.classList).find(className => className.startsWith('mccberg-tab-content-') ); // Extract the number at the end of the matched class let indexNumber = matchedClass ? matchedClass.split('-').pop() : null; // Output the number allA6TabsTitle[indexNumber-1].classList.add('open') accordionDetailA6.classList.add('open'); } function idLinkScrollFix(hash) { setTimeout(function() { var one_trust_cookie_panel = document.getElementById("onetrust-banner-sdk"); let wp_admin_bar = document.getElementById('wpadminbar'); let admin_bar_offset_height = wp_admin_bar ? wp_admin_bar.offsetHeight : 0; let cookie_present = one_trust_cookie_panel && !one_trust_cookie_panel.style.visibility; let cookie_gone = one_trust_cookie_panel && one_trust_cookie_panel.style.visibility === 'hidden'; let cookie_height = cookie_present && !cookie_gone ? one_trust_cookie_panel.offsetHeight : 0; let mastheadElement = document.getElementById('masthead'); let masthead = mastheadElement ? mastheadElement.offsetHeight : 0; let brand_headerElement = document.getElementsByClassName('brand-header')[0]; let brand_header = brand_headerElement ? brand_headerElement.offsetHeight : 0; let height_to_adjust = admin_bar_offset_height + masthead + brand_header + cookie_height + 16; let el_to_scroll_to = document.getElementById(hash.replace("#", '')); if (el_to_scroll_to) { let position = el_to_scroll_to.getBoundingClientRect(); window.scrollTo(position.left, position.top - height_to_adjust + window.scrollY); } }, 500); } </script> </body> </html>

CINXE.COM

Klinische Forschung, Arzneimittel-Entwicklung und Zulassung | MSD