Fran Aweeka, PharmD · School of Pharmacy

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My primary areas of interest include the pharmacology of drugs for HIV, malaria, and tuberculosis. I direct a laboratory, Drug Research Unit, that supports this research and the research of other UCSF investigators and researchers at other national and international institutions. I am also involved in" /> <link rel="canonical" href="https://pharmacy.ucsf.edu/fran-aweeka" /> <meta property="og:site_name" content="UCSF School of Pharmacy" /> <meta property="og:type" content="website" /> <meta property="og:title" content="Fran Aweeka, PharmD · Professor" /> <meta property="og:url" content="https://pharmacy.ucsf.edu/fran-aweeka" /> <meta property="og:description" content="Department of Clinical Pharmacy · I am a clinical scientist and professor. My primary areas of interest include the pharmacology of drugs for HIV, malaria, and tuberculosis. I direct a laboratory, Drug Research Unit, that supports this research and the research of other UCSF investigators and researchers at other national and international institutions. I am also involved in the doctor of pharmacy degree program; I serve as codirector of the Inquiry component for our School’s newest curriculum and cochair the pharmaceutical sciences pathway. I also mentor students interested in pharmacology or international research." /> <meta property="og:updated_time" content="2025-02-07T09:38:38-08:00" /> <meta property="og:image" content="https://pharmacy.ucsf.edu/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/aweeka_fran.jpg?itok=8YvmMvOz" /> <meta property="og:image:alt" content="Aweeka" /> <meta property="og:image:type" content="image/jpeg" /> <meta property="og:image:width" content="615" /> <meta property="og:image:height" content="615" /> <meta name="twitter:card" content="summary" /> <meta name="twitter:title" content="Fran Aweeka, PharmD · Professor" /> <meta name="twitter:url" content="https://pharmacy.ucsf.edu/fran-aweeka" /> <meta name="twitter:description" content="Department of Clinical Pharmacy · I am a clinical scientist and professor. My primary areas of interest include the pharmacology of drugs for HIV, malaria, and tuberculosis. I direct a laboratory," /> <meta name="twitter:image" content="https://pharmacy.ucsf.edu/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/aweeka_fran.jpg?itok=8YvmMvOz" /> <meta name="twitter:image:width" content="615" /> <meta property="og:locale" content="en_US" /> <meta name="twitter:image:height" content="615" /> <meta name="twitter:image:alt" content="Aweeka" /> <meta property="article:published_time" content="2013-03-06T14:46:32-08:00" /> <meta property="article:modified_time" content="2025-02-07T09:38:38-08:00" /> </head> <body class="html not-front not-logged-in no-sidebars page-node page-node- page-node-1206 node-type-ucsf-person" >  <div class="skip tocontent"> <a href="#content">Skip to content</a> </div> <div id="page" class="page theme-pharmacyoa is-sop-secondary is-pharmacy page-type-2"> <nav class="topbar" role="navigation" aria-label="University main menu"> <ul> <li><a href="https://www.ucsf.edu/">University of California San 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class="views-row views-row-1 views-row-odd views-row-first views-row-last"> <div class="views-field views-field-field-person-primary-dept"> <div class="field-content"><a href="https://clinicalpharmacy.ucsf.edu/">Department of Clinical Pharmacy</a></div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="moscone-container moscone-column-content clearfix"> <div class="moscone-column-content-region moscone-sidebar panel-panel"> <div class="moscone-column-content-region-inner moscone-sidebar-inner panel-panel-inner"> <div class="panel-pane pane-entity-field pane-node-field-person-headshot-photo" > <div class="pane-content"> <div class="field field-name-field-person-headshot-photo field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><div id="file-51416" class="file file-image file-image-jpeg file-entity-square-third file-entity-element-container"> <div class="content"> <picture >  <source 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srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_third/public/person/photo/aweeka_fran.jpg?itok=XYC1yjHD&timestamp=1652111249 1x" media="(min-width: 0px) and (max-width: 430px)" />  <img src="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_third/public/person/photo/aweeka_fran.jpg?itok=XYC1yjHD&timestamp=1652111249" alt="Aweeka" title="" /> </picture> <div class="field field-name-field-image-credit-term field-type-taxonomy-term-reference field-label-hidden"> <div class="field-items"> <div class="field-item even"><a href="https://www.majedphoto.com/" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">© majedphoto.com</a></div> </div> </div> </div> </div> </div></div></div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-entity-field pane-node-field-person-email" > <div class="pane-content"> <div class="field field-name-field-person-email field-type-email field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/cdn-cgi/l/email-protection#284e5a494606495f4d4d4349685d4b5b4e064d4c5d"><span class="__cf_email__" data-cfemail="375145565919564052525c56774254445119525342">[email protected]</span></a></div></div></div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-ucsf-person-profile-panel-pane-7" > <div class="pane-content"> <div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_7 view-dom-id-6cc421d74287bdf09134d221220f6946"> <div class="view-content"> <div class="views-row views-row-1 views-row-odd views-row-first views-row-last"> <div class="views-field views-field-field-campus-phone"> <div class="field-content">Phone: +1 415 476-1148</div> </div> <div class="views-field views-field-field-person-fax"> <div class="field-content">Fax: +1 415 476-0307</div> </div> </div> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-token pane-node-field-person-address-postal" > <div class="pane-content"> <div class="street-block"><div class="thoroughfare">2540 23rd Street, Rm 2110</div> <div class="premise">UCSF Box 1221</div></div> <div class="addressfield-container-inline locality-block country-US"><span class="locality">San Francisco</span>, <span class="state">CA</span> <span class="postal-code">94110</span></div> <span class="country">United States</span> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-ucsf-person-profile-panel-pane-12" > <h2 class="pane-title">Links</h2> <div class="pane-content"> <div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_12 view-dom-id-930b74d510339f80882df68c7ecfad92"> <div class="view-content"> <div class="views-row views-row-1 views-row-odd views-row-first views-row-last"> <span class="views-field views-field-field-profiles-link"> <span class="field-content"><a href="https://profiles.ucsf.edu/francesca.aweeka">UCSF Profiles</a></span> </span> </div> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-ucsf-person-profile-panel-pane-24" > <div class="pane-content"> <div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_24 view-dom-id-b315f566de2388765cf959d3c377ce57"> <div class="view-content"> <div> <h2>Affiliations</h2> </div> </div> <div class="view-footer"> <div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_16 view-dom-id-cb321f6452a322715fbe90c76e92e97b"> </div><div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_18 view-dom-id-0149b0d2a1f74318aedb2b00c1920fff"> <div class="view-header"> <h3>Education programs</h3> </div> <div class="view-content"> <div class="views-row views-row-1"> <a href="http://pharmd.ucsf.edu/">PharmD Degree Program</a> </div> </div> </div><div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_19 view-dom-id-8c5ed421d8cf0943d07b9db3d7401a96"> <div class="view-header"> <h3>UCSF centers, institutes, and research programs</h3> </div> <div class="view-content"> <div class="views-row views-row-1"> Director, <a href="https://pharm.ucsf.edu/drug-research-unit">Drug Research Unit (DRU)</a> </div> <div class="views-row views-row-2"> Pharmacology Core, <a href="http://cfar.ucsf.edu/">UCSF Center for AIDS Research</a> </div> </div> </div><div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_20 view-dom-id-30fdaf5e41b18cc93692ab9fc7085413"> </div><div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_21 view-dom-id-1da8a6e8331f890b780236a529d7d8d0"> </div><div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_22 view-dom-id-726282e3a320cf4feec6f04ecb9f51a1"> </div><div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_23 view-dom-id-5259725db60324cc1d339a0462205931"> </div> </div> </div> </div> </div> </div> </div> <div class="moscone-column-content-region moscone-content panel-panel"> <div class="moscone-column-content-region-inner moscone-content-inner panel-panel-inner"> <div class="panel-pane pane-entity-field pane-node-field-person-what-i-do-text" > <h2 class="pane-title">What I do</h2> <div class="pane-content"> <div class="field field-name-field-person-what-i-do-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>I am a clinical scientist and professor. My primary areas of interest include the pharmacology of drugs for HIV, malaria, and tuberculosis. I direct a laboratory, Drug Research Unit, that supports this research and the research of other UCSF investigators and researchers at other national and international institutions. I am also involved in the doctor of pharmacy degree program; I serve as codirector of the Inquiry component for our School’s newest curriculum and cochair the pharmaceutical sciences pathway. I also mentor students interested in pharmacology or international research.</p></div></div></div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-ucsf-person-profile-panel-pane-8 pane-float-left-fifty-departmental-research-area pane-float-left-fifty" > <h2 class="pane-title">Departmental research area</h2> <div class="pane-content"> <div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_8 view-dom-id-69c5b0259f7ed265130e477505c28914"> <div class="view-content"> <div class="views-row views-row-1 views-row-odd views-row-first views-row-last"> <div class="views-field views-field-field-research-area"> <div class="field-content"><a href="https://clinicalpharmacy.ucsf.edu/research/clinical-research">clinical research</a></div> </div> </div> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-token pane-node-field-person-dept-expertise-spec pane-float-left-fifty-my-research-expertise pane-float-left-fifty" > <h2 class="pane-title">My research expertise</h2> <div class="pane-content"> pharmacokinetic and pharmacodynamics of drugs used for HIV, malaria or tuberculosis, effective use of life-saving medications for vulnerable populations in Africa, novel treatments for HIV and HIV-associated inflammation in domestic populations </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-token pane-node-field-person-clinical-expertise pane-float-left-fifty-h2clinical-expertiseh2 pane-float-left-fifty" > <h2 class="pane-title"><h2>Clinical expertise</h2></h2> <div class="pane-content"> malaria and HIV co-infection, anti-viral drugs, anti-malarial drugs </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-ucsf-person-profile-panel-pane-14" > <div class="pane-content"> <div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_14 view-dom-id-78179226cfad05095b4ff6f9a5afdcf7"> <div class="view-content"> <div> <h2>Professional background</h2> </div> </div> <div class="view-footer"> <div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_2 view-dom-id-8eeb21fda50bff42d3046a615f45ac6e"> <div class="view-header"> <h3>Degrees</h3> </div> <div class="view-content"> <div class="views-row views-row-1"> PharmD, University of California, San Francisco, <span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="1985-01-01T00:00:00-08:00">1985</span> </div> <div class="views-row views-row-2"> BS, Biological Sciences, University of Southern California (USC), <span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="1981-01-01T00:00:00-08:00">1981</span> </div> </div> </div><div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_13 view-dom-id-e323177b2c1dca4d22fa22c2e4015c8b"> </div><div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_15 view-dom-id-de76669cc954c3e6e816a9a050960bad"> <div class="view-header"> <h3>Licensure and certifications</h3> </div> <div class="view-content"> <div class="views-row views-row-1"> Licentiate in Pharmacy, California State Board of Pharmacy, <span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="1985-01-01T00:00:00-08:00">1985</span> </div> </div> </div><div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_17 view-dom-id-17940cf8805cc6c6a4a831336a098a73"> </div> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-entity-field pane-node-field-person-research-biography" > <h2 class="pane-title">Biography</h2> <div class="pane-content"> <div class="field field-name-field-person-research-biography field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Dr. Aweeka has >25 years of experience as a clinical pharmacologist focusing on HIV, malaria and tuberculosis treatments. She is interested in deciphering pharmacokinetic (PK) and pharmacodynamic (PD) distinctions for vulnerable populations and investigating clinically relevant drug-drug interactions in patients residing in either resource replete or resource limited settings. The Drug Research Unit (DRU, also known as the Global Health Pharmacology Laboratory) for which Dr. Aweeka serves as Director, is recognized for state of the art analytical techniques for quantification of HIV, malaria, TB and oncology drugs in plasma, dried blood spots or within target cells or tissues and these methods are used to support numerous research investigations. Dr. Aweeka serves as PI on an NIH RO1 on PK/PD of malaria and antiretroviral drugs in HIV co-infected children and women in Uganda. The DRU serves as a Pharmacology Core for DAIDS programs; e.g. AIDS Clinical Trials Group and the Center for AIDS Research (supporting >30 NIH studies). Dr. Aweeka has completed the Mentor Development Program and is willing to mentor faculty, fellows, residents and students interested in an academic research career.</p> </div></div></div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-ucsf-person-profile-panel-pane-9" > <h2 class="pane-title">Research keywords</h2> <div class="pane-content"> <div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_9 columns-3 view-dom-id-afca91bd3cde35ca39ba3a4ca779c0ab"> <div class="view-content"> <div class="views-row views-row-1 views-row-odd views-row-first views-row-last"> <div class="views-field views-field-field-person-keywords-profiles"> <div class="field-content"><div class="item-list"><ul><li class="first">Malaria, Falciparum</li> <li>Lopinavir</li> <li>Benzoxazines</li> <li>HIV Protease Inhibitors</li> <li>Pregnancy Complications, Parasitic</li> <li>Antimalarials</li> <li>HIV Infections</li> <li>Nevirapine</li> <li>Anti-HIV Agents</li> <li>Ethanolamines</li> <li>Quinolines</li> <li>Ritonavir</li> <li>Artemisinins</li> <li>malaria</li> <li class="last">Fluorenes</li> </ul></div></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="moscone-container moscone-footer clearfix panel-panel"> <div class="moscone-container-inner moscone-footer-inner panel-panel-inner"> <div class="panel-pane pane-block pane-quicktabs-quicktabs-pub-news-media" > <div class="pane-content"> <div id="quicktabs-quicktabs_pub_news_media" class="quicktabs-wrapper quicktabs-style-nostyle"><div class="item-list"><ul class="quicktabs-tabs quicktabs-style-nostyle"><li class="active first last"><a href="/fran-aweeka?qt-quicktabs_pub_news_media=0#qt-quicktabs_pub_news_media" id="quicktabs-tab-quicktabs_pub_news_media-0" class="quicktabs-tab quicktabs-tab-view quicktabs-tab-view-person-related-items-panel-pane-1 active">News</a></li> </ul></div><div id="quicktabs-container-quicktabs_pub_news_media" class="quicktabs_main quicktabs-style-nostyle"><div id="quicktabs-tabpage-quicktabs_pub_news_media-0" class="quicktabs-tabpage "><div class="view view-person-related-items view-id-person_related_items view-display-id-panel_pane_1 view-dom-id-3ea521aacde9b76c87c26548ae8385ca"> <div class="view-content"> <table class="views-table cols-0"> <tbody> <tr class="odd views-row-first"> <td class="views-field views-field-counter"> 1. </td> <td class="views-field views-field-title"> <a href="/news/2022/05/update-dean-passing-torch">Update from the Dean: Passing the torch</a> </td> </tr> <tr class="even"> <td class="views-field views-field-counter"> 2. </td> <td class="views-field views-field-title"> <a href="/news/2021/04/how-train-anti-racist-pharmd-student">How to train an anti-racist PharmD student</a> </td> </tr> <tr class="odd"> <td class="views-field views-field-counter"> 3. </td> <td class="views-field views-field-title"> <a href="/news/2020/04/update-dean-we-are-rising-challenges-presented-covid-19">Update from the Dean: We are rising to the challenges presented by COVID-19</a> </td> </tr> <tr class="even"> <td class="views-field views-field-counter"> 4. </td> <td class="views-field views-field-title"> <a href="/news/2018/08/school-welcomes-incoming-pharmd-class-bold-new-curriculum">School welcomes incoming PharmD class with bold new curriculum</a> </td> </tr> <tr class="odd"> <td class="views-field views-field-counter"> 5. </td> <td class="views-field views-field-title"> <a href="/news/2018/06/showcasing-school-science-change-alumni-weekend-2018">Showcasing School science and change at Alumni Weekend 2018</a> </td> </tr> <tr class="even"> <td class="views-field views-field-counter"> 6. </td> <td class="views-field views-field-title"> <a href="/news/2017/03/update-dean-march-2017">Update from the Dean - March 2017</a> </td> </tr> <tr class="odd"> <td class="views-field views-field-counter"> 7. </td> <td class="views-field views-field-title"> <a href="/news/2016/09/renewed-funding-aweeka-study-malaria-treatment-children-hiv-africa">Renewed funding for Aweeka study on malaria treatment for children with HIV in Africa</a> </td> </tr> <tr class="even"> <td class="views-field views-field-counter"> 8. </td> <td class="views-field views-field-title"> <a href="/news/2016/08/aweeka-study-details-impact-hiv-drugs-malaria-treatment-children">Aweeka study details impact of HIV drugs on malaria treatment in children</a> </td> </tr> <tr class="odd"> <td class="views-field views-field-counter"> 9. </td> <td class="views-field views-field-title"> <a href="/news/2015/03/update-dean-springsummer-2015">Update from the Dean - Spring/Summer 2015</a> </td> </tr> <tr class="even"> <td class="views-field views-field-counter"> 10. </td> <td class="views-field views-field-title"> <a href="/news/2015/03/aweeka-co-leads-new-study-drugs-prevent-malaria-young-children-pregnant-women">Aweeka co-leads new study of drugs to prevent malaria in young children, pregnant women</a> </td> </tr> <tr class="odd"> <td class="views-field views-field-counter"> 11. </td> <td class="views-field views-field-title"> <a href="/news/2013/02/update-dean-winter-2013">Update from the Dean - Winter 2013</a> </td> </tr> <tr class="even"> <td class="views-field views-field-counter"> 12. </td> <td class="views-field views-field-title"> <a href="/news/2012/04/new-nih-funding-awarded-department-clinical-pharmacy-2011">New NIH funding awarded to the Department of Clinical Pharmacy in 2011</a> </td> </tr> <tr class="odd"> <td class="views-field views-field-counter"> 13. </td> <td class="views-field views-field-title"> <a href="/news/2011/05/clinical-pharmacy-spring-seminar-celebrates-wide-ranging-research">Clinical pharmacy spring seminar celebrates wide-ranging research</a> </td> </tr> <tr class="even"> <td class="views-field views-field-counter"> 14. </td> <td class="views-field views-field-title"> <a href="/news/2005/10/pharmacy-track-opens-door-fulbright-fellowship-research-africa">Pharmacy track opens door to Fulbright Fellowship and research in Africa</a> </td> </tr> <tr class="odd"> <td class="views-field views-field-counter"> 15. </td> <td class="views-field views-field-title"> <a href="/news/2003/03/about-leslie-wilson-more-news">About Leslie Wilson, and more news</a> </td> </tr> <tr class="even views-row-last"> <td class="views-field views-field-counter"> 16. </td> <td class="views-field views-field-title"> <a href="/news/2002/03/about-tom-james-phd-more-news">About Tom James, PhD, and more news</a> </td> </tr> </tbody> </table> </div> </div></div></div></div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-ucsf-person-profile-panel-pane-1" > <h2 class="pane-title">Publications</h2> <div class="pane-content"> <div class="view view-ucsf-person-profile view-id-ucsf_person_profile view-display-id-panel_pane_1 view-dom-id-7d582d4832c4360ee8442f8c52e30c04"> <div class="view-content"> <table class="views-table cols-0"> <tbody> <tr class="odd views-row-first"> <td class="views-field views-field-field-person-publications-list"> Thomas S, Roche E, Desai P, Pawlowska N, Bauer D, Gingrich D, Hsu E, Deitchman AN, Aweeka F, Munster PN. Characterizing safety, toxicity, and breast cancer risk reduction using a long-term fulvestrant eluting implant. Sci Rep. 2025 Jan 24; 15(1):3028. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Whalen ME, Kajubi R, Goodwin J, Orukan F, Colt M, Huang L, Richards K, Hoffmann TJ, Aweeka FT, Parikh S, Mwebaza N. Extended Treatment Duration of Artemether-Lumefantrine in Ugandan Children with HIV on Efavirenz-Based Antiretroviral Therapy: A Randomized Controlled Pharmacokinetic and Pharmacodynamic Trial. J Clin Pharmacol. 2025 Jan 24. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Mwebaza N, Roh ME, Geng YZ, Opio L, Opira B, Marzan F, Mwima MW, Ssemukuye T, Guo K, Gingrich D, Fotaki N, Kakuru A, Kizza J, Aguti M, Adrama H, Kamya M, Dorsey G, Rosenthal PJ, Aweeka FT, Huang L. Drug-Drug Interaction Between Dihydroartemisinin-Piperaquine and Sulfadoxine-Pyrimethamine During Malaria Chemoprevention in Pregnant Women. Clin Pharmacol Ther. 2024 Oct 14. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Henrich TJ, Bosch RJ, Godfrey C, Mar H, Nair A, Keefer M, Fichtenbaum C, Moisi D, Clagett B, Buck AM, Deitchman AN, Aweeka F, Li JZ, Kuritzkes DR, Lederman MM, Hsue PY, Deeks SG, ACTG A5337 Team. Sirolimus reduces T cell cycling, immune checkpoint marker expression, and HIV-1 DNA in people with HIV. Cell Rep Med. 2024 Oct 15; 5(10):101745. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Goodwin J, Kajubi R, Wang K, Li F, Wade M, Orukan F, Huang L, Whalen M, Aweeka FT, Mwebaza N, Parikh S. Persistent and multiclonal malaria parasite dynamics despite extended artemether-lumefantrine treatment in children. Nat Commun. 2024 May 07; 15(1):3817. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Ogongo P, Tran A, Marzan F, Gingrich D, Krone M, Aweeka F, Lindestam Arlehamn CS, Martin JN, Deeks SG, Hunt PW, Ernst JD. High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL-17 against M. tuberculosis antigen. Front Immunol. 2024; 15:1378040. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Ogongo P, Tran A, Marzan F, Gingrich D, Krone M, Aweeka F, Lindestam Arlehamn CS, Martin JN, Deeks SG, Hunt PW, Ernst JD. High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL17 against M. tuberculosis antigen. bioRxiv. 2024 Mar 06. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Sok V, Marzan F, Roh M, Guo K, Legac J, Mwebaza N, Dorsey G, Rosenthal PJ, Aweeka FT, Huang L. Determination of sulfadoxine and pyrimethamine in microvolume human plasma using ultra high performance liquid chromatography-tandam mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2024 Feb 15; 1234:124030. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Thomas S, Roche E, Desai P, Pawlowska N, Bauer D, Gingrich D, Hsu E, Deitchman AN, Aweeka F, Munster PN. A long-term fulvestrant eluting implant is safe, non-toxic, and reduces the risk of breast cancer in in vivo models. Res Sq. 2023 Oct 23. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Roh ME, Zongo I, Haro A, Huang L, Somé AF, Yerbanga RS, Conrad MD, Wallender E, Legac J, Aweeka F, Ouédraogo JB, Rosenthal PJ. Seasonal Malaria Chemoprevention Drug Levels and Drug Resistance Markers in Children With or Without Malaria in Burkina Faso: A Case-Control Study. J Infect Dis. 2023 10 03; 228(7):926-935. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Hong H, Aslam-Mir U, Kajubi R, Wallender E, Mwebaza N, Dorsey G, Rosenthal PJ, Aweeka FT, Huang L. Efavirenz-Based Antiretroviral Therapy but Not Pregnancy Increased Unbound Piperaquine Exposure in Women during Malaria Chemoprevention. Antimicrob Agents Chemother. 2023 04 18; 67(4):e0142722. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Whalen ME, Kajubi R, Goodwin J, Orukan F, Colt M, Huang L, Richards K, Wang K, Li F, Mwebaza N, Aweeka FT, Parikh S. The Impact of Extended Treatment With Artemether-lumefantrine on Antimalarial Exposure and Reinfection Risks in Ugandan Children With Uncomplicated Malaria: A Randomized Controlled Trial. Clin Infect Dis. 2023 02 08; 76(3):443-452. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Rahman F, Brates I, Aweeka F, Bosch RJ, Deitchman A, Nixon D, Aberg JA. Evaluating the effect of atorvastatin exposure and vitamin D levels on lipid outcomes in people with HIV-1 with suppressed HIV-1 RNA and LDL cholesterol <130 mg/dL. HIV Med. 2023 06; 24(6):749-753. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Kay K, Goodwin J, Ehrlich H, Ou J, Freeman T, Wang K, Li F, Wade M, French J, Huang L, Aweeka F, Mwebaza N, Kajubi R, Riggs M, Ruiz-Garcia A, Parikh S. Impact of Drug Exposure on Resistance Selection Following Artemether-Lumefantrine Treatment for Malaria in Children With and Without HIV in Uganda. Clin Pharmacol Ther. 2023 03; 113(3):660-669. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Hughes E, Wallender E, Kajubi R, Jagannathan P, Ochieng T, Kakuru A, Kamya MR, Clark TD, Rosenthal PJ, Dorsey G, Aweeka F, Savic RM. Piperaquine-Induced QTc Prolongation Decreases With Repeated Monthly Dihydroartemisinin-Piperaquine Dosing in Pregnant Ugandan Women. 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Clin Pharmacol Ther. 2015 Jul; 98(1):87-95. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Ofotokun I, Na LH, Landovitz RJ, Ribaudo HJ, McComsey GA, Godfrey C, Aweeka F, Cohn SE, Sagar M, Kuritzkes DR, Brown TT, Patterson KB, Para MF, Leavitt RY, Villasis-Keever A, Baugh BP, Lennox JL, Currier JS, AIDS Clinical Trials Group (ACTG) A5257 Team. Comparison of the metabolic effects of ritonavir-boosted darunavir or atazanavir versus raltegravir, and the impact of ritonavir plasma exposure: ACTG 5257. Clin Infect Dis. 2015 06 15; 60(12):1842-51. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Bartelink IH, Savic RM, Dorsey G, Ruel T, Gingrich D, Scherpbier HJ, Capparelli E, Jullien V, Young SL, Achan J, Plenty A, Charlebois E, Kamya M, Havlir D, Aweeka F. The effect of malnutrition on the pharmacokinetics and virologic outcomes of lopinavir, efavirenz and nevirapine in food insecure HIV-infected children in Tororo, Uganda. Pediatr Infect Dis J. 2015 Mar; 34(3):e63-70. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Luque AE, Cohn SE, Park JG, Cramer Y, Weinberg A, Livingston E, Klingman KL, Aweeka F, Watts DH. Depot medroxyprogesterone acetate in combination with a twice-daily lopinavir-ritonavir-based regimen in HIV-infected women showed effective contraception and a lack of clinically significant interactions, with good safety and tolerability: results of the ACTG 5283 study. Antimicrob Agents Chemother. 2015 Apr; 59(4):2094-101. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Watts DH, Stek A, Best BM, Wang J, Capparelli EV, Cressey TR, Aweeka F, Lizak P, Kreitchmann R, Burchett SK, Shapiro DE, Hawkins E, Smith E, Mirochnick M, IMPAACT 1026s study team. Raltegravir pharmacokinetics during pregnancy. J Acquir Immune Defic Syndr. 2014 Dec 01; 67(4):375-81. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Kamya MR, Kapisi J, Bigira V, Clark TD, Kinara S, Mwangwa F, Muhindo MK, Kakuru A, Aweeka FT, Huang L, Jagannathan P, Achan J, Havlir DV, Rosenthal PJ, Dorsey G. Efficacy and safety of three regimens for the prevention of malaria in young HIV-exposed Ugandan children: a randomized controlled trial. AIDS. 2014 Nov 28; 28(18):2701-9. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Aweeka FT, Hu C, Huang L, Best BM, Stek A, Lizak P, Burchett SK, Read JS, Watts H, Mirochnick M, Capparelli EV, International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT) P1026s Protocol Tea. Alteration in cytochrome P450 3A4 activity as measured by a urine cortisol assay in HIV-1-infected pregnant women and relationship to antiretroviral pharmacokinetics. HIV Med. 2015 Mar; 16(3):176-83. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Lennox JL, Landovitz RJ, Ribaudo HJ, Ofotokun I, Na LH, Godfrey C, Kuritzkes DR, Sagar M, Brown TT, Cohn SE, McComsey GA, Aweeka F, Fichtenbaum CJ, Presti RM, Koletar SL, Haas DW, Patterson KB, Benson CA, Baugh BP, Leavitt RY, Rooney JF, Seekins D, Currier JS, ACTG A5257 Team. Efficacy and tolerability of 3 nonnucleoside reverse transcriptase inhibitor-sparing antiretroviral regimens for treatment-naive volunteers infected with HIV-1: a randomized, controlled equivalence trial. Ann Intern Med. 2014 Oct 07; 161(7):461-71. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Lennox JL, Landovitz RJ, Ribaudo HJ, Ofotokun I, Na LH, Godfrey C, Kuritzkes DR, Sagar M, Brown TT, Cohn SE, McComsey GA, Aweeka F, Fichtenbaum CJ, Presti RM, Koletar SL, Haas DW, Patterson KB, Benson CA, Baugh BP, Leavitt RY, Rooney JF, Seekins D, Currier JS, ACTG A5257 Team. Summaries for patients. Nonnucleoside reverse transcriptase inhibitor-sparing antiretroviral regimens for treatment-naive volunteers infected with HIV-1. Ann Intern Med. 2014 Oct 07; 161(7):I-22. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Bigira V, Kapisi J, Clark TD, Kinara S, Mwangwa F, Muhindo MK, Osterbauer B, Aweeka FT, Huang L, Achan J, Havlir DV, Rosenthal PJ, Kamya MR, Dorsey G. Protective efficacy and safety of three antimalarial regimens for the prevention of malaria in young Ugandan children: a randomized controlled trial. PLoS Med. 2014 Aug; 11(8):e1001689. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Dooley KE, Luetkemeyer AF, Park JG, Allen R, Cramer Y, Murray S, Sutherland D, Aweeka F, Koletar SL, Marzan F, Bao J, Savic R, Haas DW, AIDS Clinical Trials Group A5306 Study Team. Phase I safety, pharmacokinetics, and pharmacogenetics study of the antituberculosis drug PA-824 with concomitant lopinavir-ritonavir, efavirenz, or rifampin. Antimicrob Agents Chemother. 2014 Sep; 58(9):5245-52. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Huang L, Haagensen J, Verotta D, Lizak P, Aweeka F, Yang K. Determination of meropenem in bacterial media by LC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Jun 15; 961:71-6. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Huang L, Lizak P, Dvorak CC, Aweeka F, Long-Boyle J. Simultaneous determination of fludarabine and clofarabine in human plasma by LC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Jun 01; 960:194-9. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Scarsi KK, Fehintola FA, Ma Q, Aweeka FT, Darin KM, Morse GD, Akinola IT, Adedeji WA, Lindegardh N, Tarning J, Ojengbede O, Adewole IF, Taiwo B, Murphy RL, Akinyinka OO, Parikh S. Disposition of amodiaquine and desethylamodiaquine in HIV-infected Nigerian subjects on nevirapine-containing antiretroviral therapy. J Antimicrob Chemother. 2014 May; 69(5):1370-6. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Kjellin LL, Dorsey G, Rosenthal PJ, Aweeka F, Huang L. Determination of the antimalarial drug piperaquine in small volume pediatric plasma samples by LC-MS/MS. Bioanalysis. 2014; 6(23):3081-9. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Bartelink IH, Savic RM, Mwesigwa J, Achan J, Clark T, Plenty A, Charlebois E, Kamya M, Young SL, Gandhi M, Havlir D, Cohan D, Aweeka F. Pharmacokinetics of lopinavir/ritonavir and efavirenz in food insecure HIV-infected pregnant and breastfeeding women in Tororo, Uganda. J Clin Pharmacol. 2014 Feb; 54(2):121-32. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Huang L, Lizak P, Aweeka F, Long-Boyle J. Determination of intracellular fludarabine triphosphate in human peripheral blood mononuclear cells by LC-MS/MS. J Pharm Biomed Anal. 2013 Dec; 86:198-203. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Gandhi M, Mwesigwa J, Aweeka F, Plenty A, Charlebois E, Ruel TD, Huang Y, Clark T, Ades V, Natureeba P, Luwedde FA, Achan J, Kamya MR, Havlir DV, Cohan D, Prevention of Malaria and HIV disease in Tororo (PROMOTE) study. Hair and plasma data show that lopinavir, ritonavir, and efavirenz all transfer from mother to infant in utero, but only efavirenz transfers via breastfeeding. J Acquir Immune Defic Syndr. 2013 Aug 15; 63(5):578-84. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Gruber VA, Rainey PM, Lum PJ, Beatty GW, Aweeka FT, McCance-Katz EF. Interactions between alcohol and the HIV entry inhibitor Maraviroc. J Int Assoc Provid AIDS Care. 2013 Nov-Dec; 12(6):375-7. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Huang L, Olson A, Gingrich D, Aweeka FT. Determination of artemether and dihydroartemisinin in human plasma with a new hydrogen peroxide stabilization method. Bioanalysis. 2013 Jun; 5(12):1501-6. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Liu L, Wang L, Huang L, Siu V, Teque F, Aweeka FT, Levy JA. Nevirapine inhibits the anti-HIV activity of CD8+ cells. J Acquir Immune Defic Syndr. 2013 Jun 01; 63(2):184-8. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Luetkemeyer AF, Rosenkranz SL, Lu D, Marzan F, Ive P, Hogg E, Swindells S, Benson CA, Grinsztejn B, Sanne IM, Havlir DV, Aweeka F, Adult AIDS Clinical Trials Group A5221 Study Team. Relationship between weight, efavirenz exposure, and virologic suppression in HIV-infected patients on rifampin-based tuberculosis treatment in the AIDS Clinical Trials Group A5221 STRIDE Study. Clin Infect Dis. 2013 Aug; 57(4):586-93. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Gwaza L, Aweeka F, Greenblatt R, Lizak P, Huang L, Guglielmo BJ. Co-administration of a commonly used Zimbabwean herbal treatment (African potato) does not alter the pharmacokinetics of lopinavir/ritonavir. Int J Infect Dis. 2013 Oct; 17(10):e857-61. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Svensson EM, Aweeka F, Park JG, Marzan F, Dooley KE, Karlsson MO. Model-based estimates of the effects of efavirenz on bedaquiline pharmacokinetics and suggested dose adjustments for patients coinfected with HIV and tuberculosis. Antimicrob Agents Chemother. 2013 Jun; 57(6):2780-7. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Creek DJ, Bigira V, McCormack S, Arinaitwe E, Wanzira H, Kakuru A, Tappero JW, Sandison TG, Lindegardh N, Nosten F, Aweeka FT, Parikh S. Pharmacokinetic predictors for recurrent malaria after dihydroartemisinin-piperaquine treatment of uncomplicated malaria in Ugandan infants. 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N Engl J Med. 2012 Nov 29; 367(22):2110-8. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Huang L, Parikh S, Rosenthal PJ, Lizak P, Marzan F, Dorsey G, Havlir D, Aweeka FT. Concomitant efavirenz reduces pharmacokinetic exposure to the antimalarial drug artemether-lumefantrine in healthy volunteers. J Acquir Immune Defic Syndr. 2012 Nov 01; 61(3):310-6. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Nikanjam M, Kabamba D, Cressey TR, Burger D, Aweeka FT, Acosta EP, Spector SA, Capparelli EV. Nevirapine exposure with WHO pediatric weight band dosing: enhanced therapeutic concentrations predicted based on extensive international pharmacokinetic experience. Antimicrob Agents Chemother. 2012 Oct; 56(10):5374-80. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Lee TM, Huang L, Johnson MK, Lizak P, Kroetz D, Aweeka F, Parikh S. 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J Acquir Immune Defic Syndr. 2010 Dec; 55(4):473-82. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Taylor SA, Lee GA, Pao VY, Anthonypillai J, Aweeka FT, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. Boosting dose ritonavir does not alter peripheral insulin sensitivity in healthy HIV-seronegative volunteers. J Acquir Immune Defic Syndr. 2010 Nov; 55(3):361-4. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Saitoh A, Capparelli E, Aweeka F, Sarles E, Singh KK, Kovacs A, Burchett SK, Wiznia A, Nachman S, Fenton T, Spector SA. CYP2C19 genetic variants affect nelfinavir pharmacokinetics and virologic response in HIV-1-infected children receiving highly active antiretroviral therapy. J Acquir Immune Defic Syndr. 2010 Jul; 54(3):285-9. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Favre D, Mold J, Hunt PW, Kanwar B, Loke P, Seu L, Barbour JD, Lowe MM, Jayawardene A, Aweeka F, Huang Y, Douek DC, Brenchley JM, Martin JN, Hecht FM, Deeks SG, McCune JM. Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease. Sci Transl Med. 2010 May 19; 2(32):32ra36. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Huang L, Lizak PS, Jayewardene AL, Marzan F, Lee MN, Aweeka FT. A modified method for determination of lumefantrine in human plasma by HPLC-UV and combination of protein precipitation and solid-phase extraction: application to a pharmacokinetic study. Anal Chem Insights. 2010 Mar 29; 5:15-23. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Pao VY, Lee GA, Taylor S, Aweeka FT, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. The protease inhibitor combination lopinavir/ritonavir does not decrease insulin secretion in healthy, HIV-seronegative volunteers. AIDS. 2010 Jan 16; 24(2):265-70. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Aweeka FT, Stek A, Best BM, Hu C, Holland D, Hermes A, Burchett SK, Read J, Mirochnick M, Capparelli EV, International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT) P1026s Protocol Tea. Lopinavir protein binding in HIV-1-infected pregnant women. 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Clin Infect Dis. 2008 Aug 01; 47(3):421-4. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Venhoff N, Venhoff AC, Jayewardene AL, Aweeka F, Lebrecht D, Walker UA. Pharmacokinetics of zidovudine and lamivudine during oral uridine supplementation with NucleomaxX. J Acquir Immune Defic Syndr. 2008 May 01; 48(1):114-6. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Capparelli EV, Aweeka F, Hitti J, Stek A, Hu C, Burchett SK, Best B, Smith E, Read JS, Watts H, Nachman S, Thorpe EM, Spector SA, Jimenez E, Shearer WT, Foca M, Mirochnick M, PACTG 1026S Study Team, PACTG P1022 Study Team. Chronic administration of nevirapine during pregnancy: impact of pregnancy on pharmacokinetics. HIV Med. 2008 Apr; 9(4):214-20. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> German PI, Aweeka FT. Clinical pharmacology of artemisinin-based combination therapies. 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Pharmacokinetic evaluation of the effects of ribavirin on zidovudine triphosphate formation: ACTG 5092s Study Team. HIV Med. 2007 Jul; 8(5):288-94. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> German P, Greenhouse B, Coates C, Dorsey G, Rosenthal PJ, Charlebois E, Lindegardh N, Havlir D, Aweeka FT. Hepatotoxicity due to a drug interaction between amodiaquine plus artesunate and efavirenz. Clin Infect Dis. 2007 Mar 15; 44(6):889-91. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Aweeka FT, Rosenkranz SL, Segal Y, Coombs RW, Bardeguez A, Thevanayagam L, Lizak P, Aberg J, Watts DH, NIAID AIDS Clinical Trials Group. The impact of sex and contraceptive therapy on the plasma and intracellular pharmacokinetics of zidovudine. AIDS. 2006 Sep 11; 20(14):1833-41. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Lee GA, Lo JC, Aweeka F, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. Single-dose lopinavir-ritonavir acutely inhibits insulin-mediated glucose disposal in healthy volunteers. Clin Infect Dis. 2006 Sep 01; 43(5):658-60. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> McGee B, Smith N, Aweeka F. HIV pharmacology: barriers to the eradication of HIV from the CNS. HIV Clin Trials. 2006 May-Jun; 7(3):142-53. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Motoya T, Thevanayagam LN, Blaschke TF, Au S, Stone JA, Jayewardene AL, Chi J, Aweeka FT. Characterization of nelfinavir binding to plasma proteins and the lack of drug displacement interactions. HIV Med. 2006 Mar; 7(2):122-8. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Deeks SG, Hoh R, Neilands TB, Liegler T, Aweeka F, Petropoulos CJ, Grant RM, Martin JN. Interruption of treatment with individual therapeutic drug classes in adults with multidrug-resistant HIV-1 infection. J Infect Dis. 2005 Nov 01; 192(9):1537-44. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Jacobson MA, Nicolau DP, Sutherland C, Smith A, Aweeka F. Pharmacokinetics of clarithromycin extended-release (ER) tablets in patients with AIDS. HIV Clin Trials. 2005 Sep-Oct; 6(5):246-53. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Borucki MJ, Spritzler J, Asmuth DM, Gnann J, Hirsch MS, Nokta M, Aweeka F, Nadler PI, Sattler F, Alston B, Nevin TT, Owens S, Waterman K, Hubbard L, Caliendo A, Pollard RB, AACTG 266 Team. A phase II, double-masked, randomized, placebo-controlled evaluation of a human monoclonal anti-Cytomegalovirus antibody (MSL-109) in combination with standard therapy versus standard therapy alone in the treatment of AIDS patients with Cytomegalovirus retinitis. Antiviral Res. 2004 Nov; 64(2):103-11. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Lee GA, Seneviratne T, Noor MA, Lo JC, Schwarz JM, Aweeka FT, Mulligan K, Schambelan M, Grunfeld C. The metabolic effects of lopinavir/ritonavir in HIV-negative men. AIDS. 2004 Mar 05; 18(4):641-9. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Gandhi M, Aweeka F, Greenblatt RM, Blaschke TF. Sex differences in pharmacokinetics and pharmacodynamics. Annu Rev Pharmacol Toxicol. 2004; 44:499-523. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Soy D, Aweeka FT, Church JA, Cunningham CK, Palumbo P, Kosel BW, Sheiner LB, Pediatric AIDS Clinical Trial Group (PACTG) Study P1005 Investigators. Population pharmacokinetics of enfuvirtide in pediatric patients with human immunodeficiency virus: searching for exposure-response relationships. Clin Pharmacol Ther. 2003 Dec; 74(6):569-80. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Floren LC, Wiznia A, Hayashi S, Jayewardene A, Stanley K, Johnson G, Nachman S, Krogstad P, Aweeka FT, Pediatric AIDS Clinical Trials Group 377 Protocol Team. Nelfinavir pharmacokinetics in stable human immunodeficiency virus-positive children: Pediatric AIDS Clinical Trials Group Protocol 377. Pediatrics. 2003 Sep; 112(3 Pt 1):e220-7. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Abrams DI, Hilton JF, Leiser RJ, Shade SB, Elbeik TA, Aweeka FT, Benowitz NL, Bredt BM, Kosel B, Aberg JA, Deeks SG, Mitchell TF, Mulligan K, Bacchetti P, McCune JM, Schambelan M. Short-term effects of cannabinoids in patients with HIV-1 infection: a randomized, placebo-controlled clinical trial. Ann Intern Med. 2003 Aug 19; 139(4):258-66. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Kosel BW, Beckerman KP, Hayashi S, Homma M, Aweeka FT. Pharmacokinetics of nelfinavir and indinavir in HIV-1-infected pregnant women. AIDS. 2003 May 23; 17(8):1195-9. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Chi J, Jayewardene AL, Stone JA, Aweeka FT. An LC-MS-MS method for the determination of nevirapine, a non-nucleoside reverse transcriptase inhibitor, in human plasma. J Pharm Biomed Anal. 2003 Apr 01; 31(5):953-9. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Chi J, Jayewardene AL, Stone JA, Motoya T, Aweeka FT. Simultaneous determination of five HIV protease inhibitors nelfinavir, indinavir, ritonavir, saquinavir and amprenavir in human plasma by LC/MS/MS. J Pharm Biomed Anal. 2002 Oct 15; 30(3):675-84. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Wohl DA, Aweeka FT, Schmitz J, Pomerantz R, Cherng DW, Spritzler J, Fox L, Simpson D, Bell D, Holohan MK, Thomas S, Robinson W, Kaplan G, Teppler H, National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group 267. Safety, tolerability, and pharmacokinetic effects of thalidomide in patients infected with human immunodeficiency virus: AIDS Clinical Trials Group 267. J Infect Dis. 2002 May 01; 185(9):1359-63. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Noor MA, Seneviratne T, Aweeka FT, Lo JC, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. Indinavir acutely inhibits insulin-stimulated glucose disposal in humans: a randomized, placebo-controlled study. AIDS. 2002 Mar 29; 16(5):F1-8. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Fichtenbaum CJ, Gerber JG, Rosenkranz SL, Segal Y, Aberg JA, Blaschke T, Alston B, Fang F, Kosel B, Aweeka F, NIAID AIDS Clinical Trials Group. Pharmacokinetic interactions between protease inhibitors and statins in HIV seronegative volunteers: ACTG Study A5047. AIDS. 2002 Mar 08; 16(4):569-77. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Kosel BW, Aweeka FT, Benowitz NL, Shade SB, Hilton JF, Lizak PS, Abrams DI. The effects of cannabinoids on the pharmacokinetics of indinavir and nelfinavir. AIDS. 2002 Mar 08; 16(4):543-50. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Herforth C, Stone JA, Jayewardene AL, Blaschke TF, Fang F, Motoya T, Aweeka FT. Determination of nelfinavir free drug concentrations in plasma by equilibrium dialysis and liquid chromatography/tandem mass spectrometry: important factors for method optimization. Eur J Pharm Sci. 2002 Mar; 15(2):185-95. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Chi J, Jayewardene A, Stone J, Gambertoglio JG, Aweeka FT. A direct determination of thymidine triphosphate concentrations without dephosphorylation in peripheral blood mononuclear cells by LC/MS/MS. J Pharm Biomed Anal. 2001 Dec; 26(5-6):829-36. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Aweeka F, Trapnell C, Chernoff M, Jayewardene A, Spritzler J, Bellibas SE, Lizak P, Jacobson J. Pharmacokinetics and pharmacodynamics of thalidomide in HIV patients treated for oral aphthous ulcers: ACTG protocol 251. AIDS Clinical Trials Group. J Clin Pharmacol. 2001 Oct; 41(10):1091-7. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Gerber JG, Rosenkranz S, Segal Y, Aberg J, D'Amico R, Mildvan D, Gulick R, Hughes V, Flexner C, Aweeka F, Hsu A, Gal J, ACTG 401 Study Team. Effect of ritonavir/saquinavir on stereoselective pharmacokinetics of methadone: results of AIDS Clinical Trials Group (ACTG) 401. J Acquir Immune Defic Syndr. 2001 Jun 01; 27(2):153-60. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Jayewardene AL, Kearney B, Stone JA, Gambertoglio JG, Aweeka FT. An LC-MS-MS method for the determination of indinavir, an HIV-1 protease inhibitor, in human plasma. J Pharm Biomed Anal. 2001 May; 25(2):309-17. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Zhang L, Price R, Aweeka F, Bellibas SE, Sheiner LB. Making the most of sparse clinical data by using a predictive-model-based analysis, illustrated with a stavudine pharmacokinetic study. Eur J Pharm Sci. 2001 Feb; 12(4):377-85. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Tsunoda SM, Aweeka FT. Drug concentration monitoring of immunosuppressive agents: focus on tacrolimus, mycophenolate mofetil and sirolimus. BioDrugs. 2000 Dec; 14(6):355-69. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Homma M, Beckerman K, Hayashi S, Jayewardene AL, Oka K, Gambertoglio JG, Aweeka FT. Liquid chromatographic determination of urinary 6beta-hydroxycortisol to assess cytochrome p-450 3A activity in HIV positive pregnant women. J Pharm Biomed Anal. 2000 Sep; 23(4):629-35. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Hayashi S, Beckerman K, Homma M, Kosel BW, Aweeka FT. Pharmacokinetics of indinavir in HIV-positive pregnant women. AIDS. 2000 May 26; 14(8):1061-2. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Kosel BW, Aweeka F. Drug interactions of antiretroviral agents. AIDS Clin Rev. 2000-2001; 193-227. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Aweeka F, Jayesekara D, Horton M, Swan S, Lambrecht L, Wilner KD, Sherwood J, Anziano RJ, Smolarek TA, Turncliff RZ. The pharmacokinetics of ziprasidone in subjects with normal and impaired renal function. Br J Clin Pharmacol. 2000; 49 Suppl 1:27S-33S. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Homma M, Jayewardene AL, Gambertoglio J, Aweeka F. High-performance liquid chromatographic determination of ribavirin in whole blood to assess disposition in erythrocytes. Antimicrob Agents Chemother. 1999 Nov; 43(11):2716-9. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Kearney BP, Aweeka FT. The penetration of anti-infectives into the central nervous system. Neurol Clin. 1999 Nov; 17(4):883-900. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Hayashi S, Jayesekera D, Jayewardene A, Shah A, Thevanayagam L, Aweeka F. Altered pharmacokinetics of indinavir by a novel nonnucleoside reverse transcriptase inhibitor (HBY-097): a pharmacokinetic evaluation in HIV-positive patients. J Clin Pharmacol. 1999 Oct; 39(10):1085-93. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Jayasekara D, Aweeka FT, Rodriguez R, Kalayjian RC, Humphreys MH, Gambertoglio JG. Antiviral therapy for HIV patients with renal insufficiency. J Acquir Immune Defic Syndr. 1999 Aug 15; 21(5):384-95. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Staprans S, Marlowe N, Glidden D, Novakovic-Agopian T, Grant RM, Heyes M, Aweeka F, Deeks S, Price RW. Time course of cerebrospinal fluid responses to antiretroviral therapy: evidence for variable compartmentalization of infection. AIDS. 1999 Jun 18; 13(9):1051-61. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Aweeka FT, Gottwald MD, Gambertoglio JG, Wright TL, Boyer TD, Pollock AS, Eldon MA, Kugler AR, Alldredge BK. Pharmacokinetics of fosphenytoin in patients with hepatic or renal disease. Epilepsia. 1999 Jun; 40(6):777-82. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Aweeka FT, Jacobson MA, Martin-Munley S, Hedman A, Schoenfeld P, Omachi R, Tsunoda S, Gambertoglio JG. Effect of renal disease and hemodialysis on foscarnet pharmacokinetics and dosing recommendations. J Acquir Immune Defic Syndr Hum Retrovirol. 1999 Apr 01; 20(4):350-7. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Aweeka F, Jayewardene A, Staprans S, Bellibas SE, Kearney B, Lizak P, Novakovic-Agopian T, Price RW. Failure to detect nelfinavir in the cerebrospinal fluid of HIV-1--infected patients with and without AIDS dementia complex. J Acquir Immune Defic Syndr Hum Retrovirol. 1999 Jan 01; 20(1):39-43. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Brody SR, Humphreys MH, Gambertoglio JG, Schoenfeld P, Cundy KC, Aweeka FT. Pharmacokinetics of cidofovir in renal insufficiency and in continuous ambulatory peritoneal dialysis or high-flux hemodialysis. Clin Pharmacol Ther. 1999 Jan; 65(1):21-8. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Jayewardene AL, Zhu F, Aweeka FT, Gambertoglio JG. Simple high-performance liquid chromatographic determination of the protease inhibitor indinavir in human plasma. J Chromatogr B Biomed Sci Appl. 1998 Apr 10; 707(1-2):203-11. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Aweeka FT, Brody SR, Jacobson M, Botwin K, Martin-Munley S. Is there a pharmacokinetic interaction between foscarnet and zalcitabine during concomitant administration? Clin Ther. 1998 Mar-Apr; 20(2):232-43. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Brody SR, Aweeka FT. Pharmacokinetics of intracellular zidovudine and its phosphorylated anabolites in the absence and presence of stavudine using an in vitro human peripheral blood mononuclear cell (PBMC) model. Int J Antimicrob Agents. 1997 Sep; 9(2):131-5. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Wolfe EJ, Mathur V, Tomlanovich S, Jung D, Wong R, Griffy K, Aweeka FT. Pharmacokinetics of mycophenolate mofetil and intravenous ganciclovir alone and in combination in renal transplant recipients. Pharmacotherapy. 1997 May-Jun; 17(3):591-8. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Aweeka FT, Kwong M, Mak M, al-Uzri A, Affrime M, Cutler D, Kahn J, Gambertoglio JG. Pharmacokinetics of recombinant human granulocyte-macrophage colony-stimulating factor: the effects of zidovudine. J Clin Pharmacol. 1996 Dec; 36(12):1107-13. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Alexander AC, Akers A, Matzke GR, Aweeka FT, Fraley DS. Disposition of foscarnet during peritoneal dialysis. Ann Pharmacother. 1996 Oct; 30(10):1106-9. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Drusano GL, Aweeka F, Gambertoglio J, Jacobson M, Polis M, Lane HC, Eaton C, Martin-Munley S. Relationship between foscarnet exposure, baseline cytomegalovirus (CMV) blood culture and the time to progression of CMV retinitis in HIV-positive patients. AIDS. 1996 Sep; 10(10):1113-9. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Tsunoda SM, Aweeka FT. The use of therapeutic drug monitoring to optimise immunosuppressive therapy. Clin Pharmacokinet. 1996 Feb; 30(2):107-40. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> d'Uscio CH, Aweeka FT, Prueksaritanont T, Tomlanovich SJ, Gupta SK, Lantz MV, Gambertoglio JG, Garovoy MR, Benet LZ. Immunopharmacodynamic studies of cyclosporine in patients awaiting renal transplantation. J Clin Pharmacol. 1995 Oct; 35(10):967-73. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Aweeka FT, Mak M, al-Uzri A, Peter K, Dett C, Franco J, Affrime M, Guerciolini R, Cutler DL, Kahn J. Oral and intravenous zidovudine pharmacokinetics: the effect of granulocyte-macrophage colony stimulating factor. J Clin Pharmacol. 1995 Sep; 35(9):856-64. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Aweeka FT, Gambertoglio JG, Kramer F, van der Horst C, Polsky B, Jayewardene A, Lizak P, Emrick L, Tong W, Jacobson MA. Foscarnet and ganciclovir pharmacokinetics during concomitant or alternating maintenance therapy for AIDS-related cytomegalovirus retinitis. Clin Pharmacol Ther. 1995 Apr; 57(4):403-12. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Aweeka FT, Tomlanovich SJ, Prueksaritanont T, Gupta SK, Benet LZ. Pharmacokinetics of orally and intravenously administered cyclosporine in pre-kidney transplant patients. J Clin Pharmacol. 1994 Jan; 34(1):60-7. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Aweeka FT, Gambertoglio JG, van der Horst C, Raasch R, Jacobson MA. Pharmacokinetics of concomitantly administered foscarnet and zidovudine for treatment of human immunodeficiency virus infection (AIDS Clinical Trials Group protocol 053). Antimicrob Agents Chemother. 1992 Aug; 36(8):1773-8. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Jacobson MA, Gambertoglio JG, Aweeka FT, Causey DM, Portale AA. Foscarnet-induced hypocalcemia and effects of foscarnet on calcium metabolism. J Clin Endocrinol Metab. 1991 May; 72(5):1130-5. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Hassanzadeh MK, Aweeka FT, Wu S, Jacobson MA, Gambertoglio JG. Determination of phosphonoformic acid in human plasma and urine by high-performance liquid chromatography with electrochemical detection. J Chromatogr. 1990 Jan 26; 525(1):133-40. </td> </tr> <tr class="even"> <td class="views-field views-field-field-person-publications-list"> Aweeka F, Gambertoglio J, Mills J, Jacobson MA. Pharmacokinetics of intermittently administered intravenous foscarnet in the treatment of acquired immunodeficiency syndrome patients with serious cytomegalovirus retinitis. Antimicrob Agents Chemother. 1989 May; 33(5):742-5. </td> </tr> <tr class="odd"> <td class="views-field views-field-field-person-publications-list"> Aweeka F, Lizak P, Garovoy M, Amend W, Birnbaum J, Gumbert M, Gambertoglio J. Interleukin-2 and immunoglobulin increases with H2-antagonists in humans. Transplant Proc. 1989 Feb; 21(1 Pt 2):1718-21. </td> </tr> <tr class="even views-row-last"> <td class="views-field views-field-field-person-publications-list"> Jacobson MA, Crowe S, Levy J, Aweeka F, Gambertoglio J, McManus N, Mills J. Effect of Foscarnet therapy on infection with human immunodeficiency virus in patients with AIDS. J Infect Dis. 1988 Oct; 158(4):862-5. </td> </tr> </tbody> </table> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div>  </div>  </div>  </div>  </div>  <div role="complementary" class="footer-make-a-gift-and-quote"> <div class="footer-make-a-gift"> <a href="https://makeagift.ucsf.edu/site/SPageServer?pagename=A1_API_GeneralGivingForm&Primary=Pharmacy">Make a gift</a> </div> <div class="footer-quote"> Science is the foundation of the School of Pharmacy’s pioneering research, individualized patient care, and unparalleled PharmD and PhD education programs. </div> </div> <div class="footer-wrapper-outer" role="contentinfo"> <div class="footer-wrapper-inner"> <div class="footer-site-names-and-disclaimer"> </div> <div class="footer menu"> <ul id="footer-menu" class="links clearfix footer-menu"><li class="0 first"><a href="https://pharmacy.ucsf.edu/news/submit/?source=footer" title="" aria-label="Submit news via the Newsletter and Social Media Submission Form">Submit news</a></li> <li class="1"><a href="https://pharmacy.ucsf.edu/suggestions" title="">Suggestions</a></li> <li class="2"><a href="https://pharmacy.ucsf.edu/support?reporturl=https%3A//pharmacy.ucsf.edu/fran-aweeka" title="">Report a problem</a></li> <li class="menu-18196"><a href="/about/contact" title="">Contact us</a></li> <li class="menu-91601"><a href="https://websites.ucsf.edu/digital-accessibility" title="">Accessibility</a></li> <li class="menu-91606"><a href="https://www.ucsf.edu/website-privacy-policy" title="">Privacy policy</a></li> <li class="menu-91611"><a href="https://websites.ucsf.edu/website-terms-use" title="">Terms of use</a></li> <li class="menu-91616"><a href="https://websites.ucsf.edu/azlist" title="">A-Z website list</a></li> <li class="menu-7861 last"><a href="/saml_login?destination=fran-aweeka" title="" rel="nofollow">Log in</a></li> </ul> </div> <div class="footer-social"> <div class="item-list"><ul><li class="first"><a href="https://www.facebook.com/ucsfpharmacy" class="facebook">Facebook</a></li> <li><a href="https://www.youtube.com/@ucsfpharmacy" class="youtube">YouTube</a></li> <li><a href="https://www.linkedin.com/showcase/ucsf-school-of-pharmacy" class="linkedin">LinkedIn</a></li> <li class="last"><a href="https://www.instagram.com/ucsfpharmacy/" class="instagram">Instagram</a></li> </ul></div> </div> <div class="copyright"> © 2002–2025 The Regents of the University of California </div> </div> </div> <script data-cfasync="false" src="/cdn-cgi/scripts/5c5dd728/cloudflare-static/email-decode.min.js"></script><script type="text/javascript" src="/sites/pharmacy.ucsf.edu/files/advagg_js/js__GM3GJPR36rRIz0TRkjC5OQwrioSyN9aoYRivDhCO_AM__qAl84FcCv2jyN22yFGS5Oc85cjd9zKX6p_cFNLGhe-M__seqvHfaz3fVlgbfb4sGxYkGyco2BfGnhCPlf7TXVcuY.js" async="async"></script> <script type="text/javascript" src="/sites/pharmacy.ucsf.edu/files/advagg_js/js__BXT3KPF6ph4oEqAPjWiNmzlSjlQ9cW6B36GuZ8Knzt8__kNEvQrCieBaWSkG2Yi7cvf5o5n825wJD1XixHxWBUFo__seqvHfaz3fVlgbfb4sGxYkGyco2BfGnhCPlf7TXVcuY.js"></script> <script type="text/javascript">window.NREUM||(NREUM={});NREUM.info={"beacon":"bam.nr-data.net","licenseKey":"3132ed34d6","applicationID":"70694569","transactionName":"YFRUNUpZDUdUUEddV1kedRRLTAxZGkNSU11oXFcPWV8GRmpdXFBdaEdfBE9nE1VSVhxBW0RXaRFdShBbWw==","queueTime":11,"applicationTime":783,"atts":"TBNXQwJDHkk=","errorBeacon":"bam.nr-data.net","agent":""}</script></body> </html>

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Fran Aweeka, PharmD · School of Pharmacy · UCSF