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Diagnostik - Mikrobiologie | Uniklinikum Erlangen
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title="Forschung"><span>Forschung</span></a><ul id="navlist2691" class="navbar__list collapse "><li class="navbar__item"><a href="/forschung/forschungsschwerpunkte/" class="navbar__link " title="Forschungsschwerpunkte"><span>Forschungsschwerpunkte</span></a></li><li class="navbar__item has-children"><a href="/forschung/forschergruppen-arbeitsgruppen/" class="navbar__link " title="Forschergruppen / Arbeitsgruppen"><span>Forschergruppen / Arbeitsgruppen</span></a><ul id="navlist2695" class="navbar__list collapse "><li class="navbar__item has-children"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-c-bogdan/" class="navbar__link " title="AG Prof. C. 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Bogdan</span></a><ul id="navlist8049" class="navbar__list collapse "><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-c-bogdan/people-and-contact/" class="navbar__link " title="People and contact"><span>People and contact</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-c-bogdan/lab-members/" class="navbar__link " title="Lab members"><span>Lab members</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-c-bogdan/open-positions/" class="navbar__link " title="Open Positions"><span>Open Positions</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-c-bogdan/relevant-publications/" class="navbar__link " title="Relevant publications"><span>Relevant publications</span></a></li></ul><button type="button" class="btn toggle" data-bs-toggle="collapse" data-bs-target="#navlist8049" aria-expanded="false" aria-controls="navlist8049" ></button></li><li class="navbar__item has-children"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-dr-r-gerlach/" class="navbar__link " title="AG Dr. R. 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Gerlach</span></a><ul id="navlist1030425" class="navbar__list collapse "><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-dr-r-gerlach/people-and-contact/" class="navbar__link " title="People and Contact"><span>People and Contact</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-dr-c-schwartz/lab-members-1/" class="navbar__link " title="Lab members"><span>Lab members</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-dr-r-gerlach/publications/" class="navbar__link " title="Publications"><span>Publications</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-dr-c-schwartz/open-positions-1/" class="navbar__link " title="Open Positions"><span>Open Positions</span></a></li></ul><button type="button" class="btn toggle" data-bs-toggle="collapse" data-bs-target="#navlist1030425" aria-expanded="false" aria-controls="navlist1030425" ></button></li><li class="navbar__item has-children"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-s-krappmann/" class="navbar__link " title="AG Prof. S. Krappmann"><span>AG Prof. S. Krappmann</span></a><ul id="navlist8077" class="navbar__list collapse "><li class="navbar__item has-children"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-s-krappmann/people-and-contact/" class="navbar__link " title="People and contact"><span>People and contact</span></a><ul id="navlist8079" class="navbar__list collapse "><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-s-krappmann/people-and-contact/prof-dr-rernat-sven-krappmann-curriculum-vitae/" class="navbar__link " title="Prof. Dr. rer.nat. Sven Krappmann/ Curriculum vitae"><span>Prof. Dr. rer.nat. Sven Krappmann/ Curriculum vitae</span></a></li></ul><button type="button" class="btn toggle" data-bs-toggle="collapse" data-bs-target="#navlist8079" aria-expanded="false" aria-controls="navlist8079" ></button></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-s-krappmann/lab-members/" class="navbar__link " title="Lab members"><span>Lab members</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-s-krappmann/publications/" class="navbar__link " title="Publications"><span>Publications</span></a></li></ul><button type="button" class="btn toggle" data-bs-toggle="collapse" data-bs-target="#navlist8077" aria-expanded="false" aria-controls="navlist8077" ></button></li><li class="navbar__item has-children"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-r-lang/" class="navbar__link " title="AG Prof. R. Lang"><span>AG Prof. R. Lang</span></a><ul id="navlist8096" class="navbar__list collapse "><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-r-lang/people-and-contact/" class="navbar__link " title="People and contact"><span>People and contact</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-r-lang/lab-members/" class="navbar__link " title="Lab members"><span>Lab members</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-r-lang/alumni/" class="navbar__link " title="Alumni"><span>Alumni</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-r-lang/publications/" class="navbar__link " title="Publications"><span>Publications</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-r-lang/open-positions/" class="navbar__link " title="Open Positions"><span>Open Positions</span></a></li></ul><button type="button" class="btn toggle" data-bs-toggle="collapse" data-bs-target="#navlist8096" aria-expanded="false" aria-controls="navlist8096" ></button></li><li class="navbar__item has-children"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-a-luehrmann/" class="navbar__link " title="AG Prof. A. L眉hrmann"><span>AG Prof. A. L眉hrmann</span></a><ul id="navlist8156" class="navbar__list collapse "><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-a-luehrmann/people-and-contact/" class="navbar__link " title="People and Contact"><span>People and Contact</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-a-luehrmann/lab-members/" class="navbar__link " title="Lab members"><span>Lab members</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-a-luehrmann/alumni/" class="navbar__link " title="Alumni"><span>Alumni</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-a-luehrmann/publications/" class="navbar__link " title="Publications"><span>Publications</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-a-luehrmann/open-positions/" class="navbar__link " title="Open Positions"><span>Open Positions</span></a></li></ul><button type="button" class="btn toggle" data-bs-toggle="collapse" data-bs-target="#navlist8156" aria-expanded="false" aria-controls="navlist8156" ></button></li><li class="navbar__item has-children"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-j-mattner/" class="navbar__link " title="AG Prof. J. Mattner"><span>AG Prof. J. Mattner</span></a><ul id="navlist8639" class="navbar__list collapse "><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-j-mattner/people-and-contact/" class="navbar__link " title="People and Contact"><span>People and Contact</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-j-mattner/lab-members/" class="navbar__link " title="Lab members"><span>Lab members</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-j-mattner/funding/" class="navbar__link " title="Funding"><span>Funding</span></a></li><li class="navbar__item"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-prof-j-mattner/publications/" class="navbar__link " title="Publications"><span>Publications</span></a></li></ul><button type="button" class="btn toggle" data-bs-toggle="collapse" data-bs-target="#navlist8639" aria-expanded="false" aria-controls="navlist8639" ></button></li><li class="navbar__item has-children"><a href="/forschung/forschergruppen-arbeitsgruppen/ag-dr-m-petter/" class="navbar__link " title="AG PD Dr. M. Petter"><span>AG PD Dr. M. 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href="https://www.uk-erlangen.de/" title="Zur Startseite des Universit盲tsklinikums Erlangen"><svg height="37" xmlns="http://www.w3.org/2000/svg" viewBox="0,0,63,64"><g><path d="M20.937+21.0438L0+21.0438L0+42.3789L20.937+42.3789L20.937+21.0438Z" opacity="1" fill="#00a579"/><path d="M62.813+21.0438L41.876+21.0438L41.876+42.3789L62.813+42.3789L62.813+21.0438Z" opacity="1" fill="#00a579"/><path d="M41.876+21.0438L20.938+21.0438L20.938+42.3789L41.876+42.3789L41.876+21.0438Z" opacity="1" fill="#2761ab"/><path d="M41.876+42.3788L20.938+42.3788L20.938+63.7138L41.876+63.7138L41.876+42.3788Z" opacity="1" fill="#00B1EB"/><path d="M41.876-0.29126L20.938-0.29126L20.938+21.0451L41.876+21.0451L41.876-0.29126Z" opacity="1" fill="#00B1EB"/></g></svg></a></li><li class="breadcrumb-item icon-arrow_right"><a class="breadcrumb-link" href="/" title="Mikrobiologie"><span class="breadcrumb-text">Mikrobiologie</span></a></li><li class="breadcrumb-item icon-arrow_right "><a class="breadcrumb-link" href="/aerzte-zuweiser/" title="脛rzte & Zuweiser"><span class="breadcrumb-text">脛rzte & Zuweiser</span></a></li><li class="breadcrumb-item icon-arrow_right active" aria-current="page"><span class="breadcrumb-text">Diagnostik</span></li></ol></div></nav><main id="page-content" class="bp-page-content main-section"><!--TYPO3SEARCH_begin--><div class="section section-before-content"></div><div class="section section-default"><div id="c14634" class=" frame frame-default frame-type-text frame-layout-default frame-size-default frame-height-default frame-background-none frame-space-before-none frame-space-after-none frame-no-backgroundimage"><div class="frame-group-container"><div class="frame-group-inner"><div class="frame-container frame-container-default"><div class="frame-inner"><div class="frame-header"><h2 class="element-header "><span>Moderne Mikrobiologische Diagnostik mit Bereitschaftsdienst</span></h2></div><p>Die diagnostische Abteilung ist seit 2005 akkreditiert und unterzieht sich st盲ndig aktuellen Verfahren der externen Qualit盲tssicherung. Es werden j盲hrlich 眉ber 90.000 Proben von Patienten aus dem Universit盲tsklinikum und von externen Einsendern untersucht. Ziel ist es, bei Patienten mit Verdacht auf eine Infektionserkrankung m枚glichst schnell den relevanten Erreger (Bakterien, Pilze oder Parasiten) und dessen Empfindlichkeit gegen眉ber Antiinfektiva (Medikamente gegen Infektionen) festzustellen und dadurch den 脛rzten am Krankenbett wertvolle Hinweise f眉r die richtige therapeutische Behandlung zu geben. Der Kontakt zwischen Labor und den Kliniken ist eng: Wichtige Befunde werden unmittelbar bereits telefonisch mitgeteilt und dabei m枚gliche weitere diagnostische Ma脽nahmen oder Therapieschritte diskutiert. Kritische F盲lle auf Intensivstationen oder Stationen mit Patienten, deren Immunabwehr geschw盲cht ist, werden zudem vor Ort im Rahmen einer w枚chentlichen Visite besprochen. Bei infektiologischen Notf盲llen, z.B. Verdacht auf bakterielle Entz眉ndungen im Auge oder der Hirnh盲ute, kann durch eine Schnelldiagnostik die antiinfektive Behandlung verbessert werden. Hierf眉r steht au脽erhalb der regul盲ren Dienstzeiten rund um die Uhr ein mikrobiologischer Bereitschaftsdienst zur Verf眉gung.</p><p>Auch im Zeitalter der molekularen Verfahren hat die Mikroskopie und die Kultur von Bakterien und Pilzen auf N盲hrb枚den nach wie vor eine zentrale diagnostische Bedeutung: Durch die F盲rbung von speziell vorbereiteten Untersuchungsmaterialien ergeben sich schnell erste Hinweise auf eine Infektion, w盲hrend es durch die Anzucht m枚glich ist, Krankheitserreger von der Normalflora zu trennen, die Art der Bakterien zu bestimmen und vor allem die Empfindlichkeit bzw. Resistenz gegen眉ber Antiinfektiva zu testen. Dies setzt voraus, dass geeignetes Patientenmaterial unter m枚glichst sterilen Bedingungen gewonnen und ohne Inaktivierung (Fixierung), d.h. naturbelassen, eingesandt wird.</p><p>Bei manchen Infektionen (z.B. Borreliose, Geschlechtskrankheiten wie der Syphilis, Atemwegsinfektionen mit Coxiellen, Chlamydien oder Mykoplasmen) lassen sich die Erreger nicht oder nicht zeitnah anz眉chten. Die Infektion kann hier zum einen indirekt 眉ber serologische Verfahren, d.h. den Nachweis der spezifischen, vom Patienten gebildeten Antik枚rper gef眉hrt werden. In manchen F盲llen, wie z.B. bei Verdacht auf Infektionen mit dem Pilz Aspergillus, ist auch der hochsensitive Nachweis von Erregerbestandteilen (Antigenen) wegweisend. Als dritte M枚glichkeit existiert der Erregernachweis 眉ber molekularbiologische Verfahren, die heute aus der mikrobiologischen Diagnostik nicht mehr wegzudenken sind und die vor allem auf der Vermehrung von Nukleins盲uren (Polymerase-Ketten-Reaktion, PCR) basieren.</p></div></div></div></div></div></div><div class="section section-before-footer"><!-- Shortcut c80154 --><div id="c80064" class=" frame frame-default frame-type-custom_logoslider frame-layout-default frame-size-default frame-height-default frame-background-none frame-space-before-none frame-space-after-none frame-no-backgroundimage"><div class="frame-group-container"><div class="frame-group-inner"><div class="frame-container frame-container-default"><div class="frame-inner"><div class="logoslider-wrapper logoslider-wrapper-"><div class="swiper-container logoslider "><div class="swiper-wrapper"><div class="swiper-slide"><a href="https://www.med.fau.de" target="_blank" rel="noreferrer" title="FAU - Friedrich Alexander 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