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vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Usage_médical"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Usage médical</span> </div> </a> <ul id="toc-Usage_médical-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Effets_secondaires" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Effets_secondaires"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Effets secondaires</span> </div> </a> <ul id="toc-Effets_secondaires-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Histoire" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Histoire"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Histoire</span> </div> </a> <ul id="toc-Histoire-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Références" class="vector-toc-list-item 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id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Basculer la table des matières" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Basculer la table des matières</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Carisoprodol</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Aller à un article dans une autre langue. Disponible en 20 langues." > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-20" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">20 langues</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%83%D8%A7%D8%B1%D9%8A%D8%B3%D9%88%D8%A8%D8%B1%D9%88%D8%AF%D9%88%D9%84" title="كاريسوبرودول – arabe" lang="ar" hreflang="ar" data-title="كاريسوبرودول" data-language-autonym="العربية" data-language-local-name="arabe" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D9%83%D8%A7%D8%B1%D9%8A%D8%B2%D9%88%D8%A8%D8%B1%D9%88%D8%AF%D9%88%D9%84" title="كاريزوبرودول – South Azerbaijani" lang="azb" hreflang="azb" data-title="كاريزوبرودول" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/Carisoprodol" title="Carisoprodol – gallois" lang="cy" hreflang="cy" data-title="Carisoprodol" data-language-autonym="Cymraeg" data-language-local-name="gallois" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Carisoprodol" title="Carisoprodol – allemand" lang="de" hreflang="de" data-title="Carisoprodol" data-language-autonym="Deutsch" data-language-local-name="allemand" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Carisoprodol" title="Carisoprodol – anglais" lang="en" hreflang="en" data-title="Carisoprodol" data-language-autonym="English" data-language-local-name="anglais" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Carisoprodol" title="Carisoprodol – espagnol" lang="es" hreflang="es" data-title="Carisoprodol" data-language-autonym="Español" data-language-local-name="espagnol" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%DA%A9%D8%A7%D8%B1%DB%8C%D8%B3%D9%88%D9%BE%D8%B1%D9%88%D8%AF%D9%88%D9%84" title="کاریسوپرودول – persan" lang="fa" hreflang="fa" data-title="کاریسوپرودول" data-language-autonym="فارسی" data-language-local-name="persan" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Karisoprodoli" title="Karisoprodoli – finnois" lang="fi" hreflang="fi" data-title="Karisoprodoli" data-language-autonym="Suomi" data-language-local-name="finnois" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Karisoprodol" title="Karisoprodol – indonésien" lang="id" hreflang="id" data-title="Karisoprodol" data-language-autonym="Bahasa Indonesia" data-language-local-name="indonésien" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-ig mw-list-item"><a href="https://ig.wikipedia.org/wiki/Carisoprodol" title="Carisoprodol – igbo" lang="ig" hreflang="ig" data-title="Carisoprodol" data-language-autonym="Igbo" data-language-local-name="igbo" class="interlanguage-link-target"><span>Igbo</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%82%AB%E3%83%AA%E3%82%BD%E3%83%97%E3%83%AD%E3%83%89%E3%83%BC%E3%83%AB" title="カリソプロドール – japonais" lang="ja" hreflang="ja" data-title="カリソプロドール" data-language-autonym="日本語" data-language-local-name="japonais" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Karisoprodol" title="Karisoprodol – norvégien bokmål" lang="nb" hreflang="nb" data-title="Karisoprodol" data-language-autonym="Norsk bokmål" data-language-local-name="norvégien bokmål" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%95%E0%AC%BE%E0%AC%B0%E0%AC%BF%E0%AC%B8%E0%AD%8B%E0%AC%AA%E0%AD%8D%E0%AC%B0%E0%AD%8B%E0%AC%A1%E0%AD%8B%E0%AC%B2" title="କାରିସୋପ୍ରୋଡୋଲ – odia" lang="or" hreflang="or" data-title="କାରିସୋପ୍ରୋଡୋଲ" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="odia" class="interlanguage-link-target"><span>ଓଡ଼ିଆ</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Carisoprodol" title="Carisoprodol – portugais" lang="pt" hreflang="pt" data-title="Carisoprodol" data-language-autonym="Português" data-language-local-name="portugais" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Carisoprodol" title="Carisoprodol – roumain" lang="ro" hreflang="ro" data-title="Carisoprodol" data-language-autonym="Română" data-language-local-name="roumain" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Karisoprodol" title="Karisoprodol – serbo-croate" lang="sh" hreflang="sh" data-title="Karisoprodol" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="serbo-croate" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Karisoprodol" title="Karisoprodol – serbe" lang="sr" hreflang="sr" data-title="Karisoprodol" data-language-autonym="Српски / srpski" data-language-local-name="serbe" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Karisoprodol" title="Karisoprodol – suédois" lang="sv" hreflang="sv" data-title="Karisoprodol" data-language-autonym="Svenska" data-language-local-name="suédois" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Carisoprodol" title="Carisoprodol – turc" lang="tr" hreflang="tr" data-title="Carisoprodol" data-language-autonym="Türkçe" data-language-local-name="turc" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E5%8D%A1%E7%AB%8B%E6%99%AE%E5%A4%9A" title="卡立普多 – chinois" lang="zh" hreflang="zh" data-title="卡立普多" data-language-autonym="中文" data-language-local-name="chinois" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q416905#sitelinks-wikipedia" title="Modifier les liens interlangues" class="wbc-editpage">Modifier les liens</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Espaces de noms"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Carisoprodol" title="Voir le contenu de la page [c]" accesskey="c"><span>Article</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/Discussion:Carisoprodol" rel="discussion" title="Discussion au sujet de cette page de contenu [t]" accesskey="t"><span>Discussion</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" 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href="/wiki/Carisoprodol"><span>Lire</span></a></li><li id="ca-ve-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Carisoprodol&veaction=edit" title="Modifier cette page [v]" accesskey="v"><span>Modifier</span></a></li><li id="ca-edit" class="collapsible vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Carisoprodol&action=edit" title="Modifier le wikicode de cette page [e]" accesskey="e"><span>Modifier le code</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Carisoprodol&action=history" title="Historique des versions de cette page [h]" accesskey="h"><span>Voir l’historique</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Outils de la page"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="Outils" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Outils</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Outils</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">déplacer vers la barre latérale</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">masquer</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="Plus d’options" > <div class="vector-menu-heading"> Actions </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/Carisoprodol"><span>Lire</span></a></li><li id="ca-more-ve-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Carisoprodol&veaction=edit" title="Modifier cette page [v]" accesskey="v"><span>Modifier</span></a></li><li id="ca-more-edit" class="collapsible vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Carisoprodol&action=edit" title="Modifier le wikicode de cette page [e]" accesskey="e"><span>Modifier le code</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Carisoprodol&action=history"><span>Voir l’historique</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> Général </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/Sp%C3%A9cial:Pages_li%C3%A9es/Carisoprodol" title="Liste des pages liées qui pointent sur celle-ci [j]" accesskey="j"><span>Pages liées</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/Sp%C3%A9cial:Suivi_des_liens/Carisoprodol" rel="nofollow" title="Liste des modifications récentes des pages appelées par celle-ci [k]" accesskey="k"><span>Suivi des pages liées</span></a></li><li id="t-upload" class="mw-list-item"><a href="/wiki/Aide:Importer_un_fichier" title="Téléverser des fichiers [u]" accesskey="u"><span>Téléverser un fichier</span></a></li><li id="t-specialpages" class="mw-list-item"><a href="/wiki/Sp%C3%A9cial:Pages_sp%C3%A9ciales" title="Liste de toutes les pages spéciales [q]" accesskey="q"><span>Pages spéciales</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=Carisoprodol&oldid=218577184" title="Adresse permanente de cette version de cette page"><span>Lien permanent</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=Carisoprodol&action=info" title="Davantage d’informations sur cette page"><span>Informations sur la page</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=Sp%C3%A9cial:Citer&page=Carisoprodol&id=218577184&wpFormIdentifier=titleform" title="Informations sur la manière de citer cette page"><span>Citer cette page</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=Sp%C3%A9cial:UrlShortener&url=https%3A%2F%2Ffr.wikipedia.org%2Fwiki%2FCarisoprodol"><span>Obtenir l'URL raccourcie</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=Sp%C3%A9cial:QrCode&url=https%3A%2F%2Ffr.wikipedia.org%2Fwiki%2FCarisoprodol"><span>Télécharger le code QR</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" > <div class="vector-menu-heading"> Imprimer / exporter </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-create_a_book" class="mw-list-item"><a href="/w/index.php?title=Sp%C3%A9cial:Livre&bookcmd=book_creator&referer=Carisoprodol"><span>Créer un livre</span></a></li><li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=Sp%C3%A9cial:DownloadAsPdf&page=Carisoprodol&action=show-download-screen"><span>Télécharger comme PDF</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=Carisoprodol&printable=yes" title="Version imprimable de cette page [p]" accesskey="p"><span>Version imprimable</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> Dans d’autres projets </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="wb-otherproject-link wb-otherproject-commons mw-list-item"><a href="https://commons.wikimedia.org/wiki/Category:Carisoprodol" hreflang="en"><span>Wikimedia Commons</span></a></li><li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q416905" title="Lien vers l’élément dans le dépôt de données connecté [g]" accesskey="g"><span>Élément Wikidata</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Outils de la page"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Apparence"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Apparence</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">déplacer vers la barre latérale</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">masquer</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">Un article de Wikipédia, l'encyclopédie libre.</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="fr" dir="ltr"><p class="mw-empty-elt"> </p> <table class="infobox_v2 infobox infobox--frwiki noarchive"> <tbody><tr> <td colspan="2" class="entete medecine" style="background-color:#6ABF84;color:#000000;">Carisoprodol<style data-mw-deduplicate="TemplateStyles:r213937691">.mw-parser-output .entete.medecine{background-image:url("//upload.wikimedia.org/wikipedia/commons/2/23/Picto_infobox_med.png")}</style> </td></tr> <tr><td colspan="2" style="text-align:center; line-height: 1.5em;"><span typeof="mw:File/Frameless"><a href="/wiki/Fichier:Carisoprodol-2D-skeletal.png" class="mw-file-description"><img alt="Image illustrative de l’article Carisoprodol" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/27/Carisoprodol-2D-skeletal.png/160px-Carisoprodol-2D-skeletal.png" decoding="async" width="160" height="67" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/27/Carisoprodol-2D-skeletal.png/240px-Carisoprodol-2D-skeletal.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/27/Carisoprodol-2D-skeletal.png/320px-Carisoprodol-2D-skeletal.png 2x" data-file-width="1100" data-file-height="462" /></a></span> </td></tr> <tr> <th colspan="2" style="padding:4px; text-align:center; background-color:#6ABF84; color:#000000">Informations générales</th></tr> <tr> <th scope="row"><a href="/wiki/M%C3%A9dicament" title="Médicament">Princeps</a> </th> <td>Soma<sup id="cite_ref-drugs.com_1-0" class="reference"><a href="#cite_note-drugs.com-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup> </td> </tr> <tr> <th colspan="2" style="padding:4px; text-align:center; background-color:#6ABF84; color:#000000"><a href="/wiki/Pharmacocin%C3%A9tique" title="Pharmacocinétique">Données pharmacocinétiques</a></th></tr> <tr> <th scope="row"><a href="/wiki/M%C3%A9tabolite" title="Métabolite">Métabolite(s)</a> </th> <td><a href="/wiki/Meprobamate" class="mw-redirect" title="Meprobamate">Meprobamate</a> </td> </tr> <tr> <th scope="row"><a href="/wiki/Excr%C3%A9tion" title="Excrétion">Excrétion</a> </th> <td> <p>Rein </p> </td> </tr> <tr> <th colspan="2" style="padding:4px; text-align:center; background-color:#6ABF84; color:#000000">Identification</th></tr> <tr> <th scope="row"><a href="/wiki/Num%C3%A9ro_CAS" title="Numéro CAS">N<sup>o</sup> CAS</a> </th> <td><span class="reflink plainlinksneverexpand"><span class="noarchive"><a class="external text" href="//tools.wmflabs.org/magnustools/cas.php?cas=78-44-4&language=fr&title=Carisoprodol">78-44-4</a> <span class="wd_p231"><span class="noprint wikidata-linkback skin-invert"><span class="mw-valign-baseline noviewer" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q416905?uselang=fr#P231" title="Voir et modifier les données sur Wikidata"><img alt="Voir et modifier les données sur Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/10px-Blue_pencil.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/15px-Blue_pencil.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/20px-Blue_pencil.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></span></span></span> </td> </tr> <tr> <th scope="row"> N<sup>o</sup> <a href="/wiki/Agence_europ%C3%A9enne_des_produits_chimiques" title="Agence européenne des produits chimiques">ECHA</a> </th> <td><span class="plainlinks"><span class="noarchive"><a rel="nofollow" class="external text" href="http://echa.europa.eu/fr/substance-information/-/substanceinfo/100.001.017">100.001.017</a></span></span></td> </tr> <tr> <th scope="row"><a href="/wiki/Classification_ATC" title="Classification ATC">Code ATC</a> </th> <td>M03BA02 </td> </tr> <tr> <th scope="row">DrugBank </th> <td><span class="plainlinks"><span class="noarchive"><a rel="nofollow" class="external text" href="http://www.drugbank.ca/drugs/DBDB00395">DB00395</a> <span class="wd_p715"><span class="noprint wikidata-linkback skin-invert"><span class="mw-valign-baseline noviewer" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q416905?uselang=fr#P715" title="Voir et modifier les données sur Wikidata"><img alt="Voir et modifier les données sur Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/10px-Blue_pencil.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/15px-Blue_pencil.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/20px-Blue_pencil.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></span></span></span> </td> </tr> <tr> <td class="navigation-only" colspan="2" style="border-top: 2px #6ABF84 solid; font-size: 80%; background:inherit; color: inherit; text-align: right;"><span class="plainlinks" style="float:left;"><a class="external text" href="https://fr.wikipedia.org/w/index.php?title=Carisoprodol&action=edit&section=0"><span class="infodoc">modifier</span></a></span> <span typeof="mw:File"><a href="/wiki/Mod%C3%A8le:Infobox_M%C3%A9dicament" title="Consultez la documentation du modèle"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/38/Info_Simple.svg/12px-Info_Simple.svg.png" decoding="async" width="12" height="12" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/38/Info_Simple.svg/18px-Info_Simple.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/38/Info_Simple.svg/24px-Info_Simple.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></td> </tr> </tbody></table> <p>Le <b>carisoprodol</b> est un médicament utilisé contre les douleurs musculaires. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Mécanisme_d'action"><span id="M.C3.A9canisme_d.27action"></span>Mécanisme d'action</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Carisoprodol&veaction=edit&section=1" title="Modifier la section : Mécanisme d'action" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Carisoprodol&action=edit&section=1" title="Modifier le code source de la section : Mécanisme d'action"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>La façon dont il fonctionne n’est pas claire. On pense que certains de ses effets se produisent après avoir été convertis en <a href="/wiki/M%C3%A9probamate" title="Méprobamate">méprobamate</a><sup id="cite_ref-AHFS2019_2-0" class="reference"><a href="#cite_note-AHFS2019-2"><span class="cite_crochet">[</span>2<span class="cite_crochet">]</span></a></sup><sup class="reference cite_virgule">,</sup><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite_crochet">[</span>3<span class="cite_crochet">]</span></a></sup>. </p> <div class="mw-heading mw-heading2"><h2 id="Usage_médical"><span id="Usage_m.C3.A9dical"></span>Usage médical</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Carisoprodol&veaction=edit&section=2" title="Modifier la section : Usage médical" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Carisoprodol&action=edit&section=2" title="Modifier le code source de la section : Usage médical"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>L’utilisation n’est approuvée que pour une durée maximale de trois semaines<sup id="cite_ref-AHFS2019_2-1" class="reference"><a href="#cite_note-AHFS2019-2"><span class="cite_crochet">[</span>2<span class="cite_crochet">]</span></a></sup>. Les effets commencent généralement dans la demi-heure et durent jusqu'à six heures<sup id="cite_ref-AHFS2019_2-2" class="reference"><a href="#cite_note-AHFS2019-2"><span class="cite_crochet">[</span>2<span class="cite_crochet">]</span></a></sup>. Il est pris par voie orale<sup id="cite_ref-AHFS2019_2-3" class="reference"><a href="#cite_note-AHFS2019-2"><span class="cite_crochet">[</span>2<span class="cite_crochet">]</span></a></sup>. </p> <div class="mw-heading mw-heading2"><h2 id="Effets_secondaires">Effets secondaires</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Carisoprodol&veaction=edit&section=3" title="Modifier la section : Effets secondaires" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Carisoprodol&action=edit&section=3" title="Modifier le code source de la section : Effets secondaires"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Les effets secondaires courants comprennent des maux de tête, des étourdissements et de la <a href="/wiki/Somnolence" class="mw-redirect" title="Somnolence">somnolence</a>; les effets secondaires graves peuvent inclure une dépendance, des réactions allergiques ou des <a href="/wiki/Convulsions" class="mw-redirect" title="Convulsions">convulsions</a>. Chez les personnes allergiques aux sulfamides, certaines formulations peuvent entraîner des problèmes. La sécurité pendant la grossesse et l’allaitement n’est pas claire. </p> <div class="mw-heading mw-heading2"><h2 id="Histoire">Histoire</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Carisoprodol&veaction=edit&section=4" title="Modifier la section : Histoire" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Carisoprodol&action=edit&section=4" title="Modifier le code source de la section : Histoire"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>L'usage médical du carisoprodol a été approuvé aux États-Unis en 1959<sup id="cite_ref-AHFS2019_2-4" class="reference"><a href="#cite_note-AHFS2019-2"><span class="cite_crochet">[</span>2<span class="cite_crochet">]</span></a></sup>. Son approbation en Europe a été retirée en 2008<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite_crochet">[</span>4<span class="cite_crochet">]</span></a></sup>. Il est disponible sous forme de <a href="/wiki/M%C3%A9dicament_g%C3%A9n%C3%A9rique" title="Médicament générique">médicament générique</a><sup id="cite_ref-AHFS2019_2-5" class="reference"><a href="#cite_note-AHFS2019-2"><span class="cite_crochet">[</span>2<span class="cite_crochet">]</span></a></sup>. Aux États-Unis, le coût de gros est inférieur à 0,10 dollar américain par dose<sup id="cite_ref-ref_5-0" class="reference"><a href="#cite_note-ref-5"><span class="cite_crochet">[</span>5<span class="cite_crochet">]</span></a></sup>. En 2017, il s'agissait du 255e médicament le plus prescrit aux États-Unis, avec plus d'un million d'ordonnances<sup id="cite_ref-ref1_6-0" class="reference"><a href="#cite_note-ref1-6"><span class="cite_crochet">[</span>6<span class="cite_crochet">]</span></a></sup><sup class="reference cite_virgule">,</sup><sup id="cite_ref-ref2_7-0" class="reference"><a href="#cite_note-ref2-7"><span class="cite_crochet">[</span>7<span class="cite_crochet">]</span></a></sup>. Aux États-Unis, il s’agit d’une substance contrôlée <a href="/wiki/Controlled_Substances_Act" title="Controlled Substances Act">de l’annexe IV</a><sup id="cite_ref-AHFS2019_2-6" class="reference"><a href="#cite_note-AHFS2019-2"><span class="cite_crochet">[</span>2<span class="cite_crochet">]</span></a></sup>. </p> <div class="mw-heading mw-heading2"><h2 id="Références"><span id="R.C3.A9f.C3.A9rences"></span>Références</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Carisoprodol&veaction=edit&section=5" title="Modifier la section : Références" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Carisoprodol&action=edit&section=5" title="Modifier le code source de la section : Références"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-drugs.com-1"><span class="mw-cite-backlink noprint"><a href="#cite_ref-drugs.com_1-0">↑</a> </span><span class="reference-text"><span class="ouvrage"><span class="noarchive">« <a rel="nofollow" class="external text" href="https://www.drugs.com/international/carisoprodol.html"><cite style="font-style:normal;">Carisoprodol</cite></a> » <small class="plainlinks cachelinks">[<a rel="nofollow" class="external text" href="https://web.archive.org/web/20170831175744/https://www.drugs.com/international/carisoprodol.html">archive du <time class="nowrap" datetime="2017-08-31" data-sort-value="2017-08-31">31 août 2017</time></a>]</small></span>, sur <span class="italique">drugs.com</span> <small style="line-height:1em;">(consulté le <time class="nowrap" datetime="2017-04-16" data-sort-value="2017-04-16">16 avril 2017</time>)</small></span></span> </li> <li id="cite_note-AHFS2019-2"><span class="mw-cite-backlink noprint">↑ <sup><a href="#cite_ref-AHFS2019_2-0">a</a> <a href="#cite_ref-AHFS2019_2-1">b</a> <a href="#cite_ref-AHFS2019_2-2">c</a> <a href="#cite_ref-AHFS2019_2-3">d</a> <a href="#cite_ref-AHFS2019_2-4">e</a> <a href="#cite_ref-AHFS2019_2-5">f</a> et <a href="#cite_ref-AHFS2019_2-6">g</a></sup> </span><span class="reference-text"><span class="ouvrage"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> <span class="noarchive">« <a rel="nofollow" class="external text" href="https://www.drugs.com/monograph/carisoprodol.html"><cite style="font-style:normal;" lang="en">Carisoprodol Monograph for Professionals</cite></a> » <small class="plainlinks cachelinks">[<a rel="nofollow" class="external text" href="https://web.archive.org/web/20190618020542/https://www.drugs.com/monograph/carisoprodol.html">archive du <time class="nowrap" datetime="2019-06-18" data-sort-value="2019-06-18">18 juin 2019</time></a>]</small></span>, sur <span class="italique">Drugs.com</span>, American Society of Health-System Pharmacists <small style="line-height:1em;">(consulté le <time class="nowrap" datetime="2019-04-08" data-sort-value="2019-04-08">8 avril 2019</time>)</small></span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink noprint"><a href="#cite_ref-3">↑</a> </span><span class="reference-text"><span class="ouvrage"><span class="noarchive">« <a rel="nofollow" class="external text" href="https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ab22f1be-16c8-45b6-adaf-09e08bf7a545"><cite style="font-style:normal;">DailyMed - carisoprodol tablet</cite></a> » <small class="plainlinks cachelinks">[<a rel="nofollow" class="external text" href="https://web.archive.org/web/20201124060233/https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ab22f1be-16c8-45b6-adaf-09e08bf7a545">archive du <time class="nowrap" datetime="2020-11-24" data-sort-value="2020-11-24">24 novembre 2020</time></a>]</small></span>, sur <span class="italique">dailymed.nlm.nih.gov</span> <small style="line-height:1em;">(consulté le <time class="nowrap" datetime="2019-04-08" data-sort-value="2019-04-08">8 avril 2019</time>)</small></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink noprint"><a href="#cite_ref-4">↑</a> </span><span class="reference-text"><span class="ouvrage" id="2007"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> <span class="noarchive">« <a rel="nofollow" class="external text" href="https://www.ema.europa.eu/en/medicines/human/referrals/carisoprodol"><cite style="font-style:normal;" lang="en">Carisoprodol</cite></a> » <small class="plainlinks cachelinks">[<a rel="nofollow" class="external text" href="https://web.archive.org/web/20190408134933/https://www.ema.europa.eu/en/medicines/human/referrals/carisoprodol">archive du <time class="nowrap" datetime="2019-04-08" data-sort-value="2019-04-08">8 avril 2019</time></a>]</small></span>, <span class="italique">European Medicines Agency</span>, <time class="nowrap" datetime="2007-11-15" data-sort-value="2007-11-15">15 novembre 2007</time> <small style="line-height:1em;">(consulté le <time class="nowrap" datetime="2019-04-08" data-sort-value="2019-04-08">8 avril 2019</time>)</small></span></span> </li> <li id="cite_note-ref-5"><span class="mw-cite-backlink noprint"><a href="#cite_ref-ref_5-0">↑</a> </span><span class="reference-text"><span class="ouvrage"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> <span class="noarchive">« <a rel="nofollow" class="external text" href="https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6"><cite style="font-style:normal;" lang="en">NADAC as of 2019-02-27 | Data.Medicaid.gov</cite></a> » <small class="plainlinks cachelinks">[<a rel="nofollow" class="external text" href="https://web.archive.org/web/20190306044447/https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6">archive du <time class="nowrap" datetime="2019-03-06" data-sort-value="2019-03-06">6 mars 2019</time></a>]</small></span>, <span class="italique">Centers for Medicare and Medicaid Services</span> <small style="line-height:1em;">(consulté le <time class="nowrap" datetime="2019-04-08" data-sort-value="2019-04-08">8 avril 2019</time>)</small></span></span> </li> <li id="cite_note-ref1-6"><span class="mw-cite-backlink noprint"><a href="#cite_ref-ref1_6-0">↑</a> </span><span class="reference-text"><span class="ouvrage"><span class="noarchive">« <a rel="nofollow" class="external text" href="https://clincalc.com/DrugStats/Top300Drugs.aspx"><cite style="font-style:normal;">The Top 300 of 2020</cite></a> » <small class="plainlinks cachelinks">[<a rel="nofollow" class="external text" href="https://web.archive.org/web/20210212142534/https://clincalc.com/DrugStats/Top300Drugs.aspx">archive du <time class="nowrap" datetime="2021-02-12" data-sort-value="2021-02-12">12 février 2021</time></a>]</small></span>, <span class="italique">ClinCalc</span> <small style="line-height:1em;">(consulté le <time class="nowrap" datetime="2020-04-11" data-sort-value="2020-04-11">11 avril 2020</time>)</small></span></span> </li> <li id="cite_note-ref2-7"><span class="mw-cite-backlink noprint"><a href="#cite_ref-ref2_7-0">↑</a> </span><span class="reference-text"><span class="ouvrage"><span class="noarchive">« <a rel="nofollow" class="external text" href="https://clincalc.com/DrugStats/Drugs/Carisoprodol"><cite style="font-style:normal;">Carisoprodol - Drug Usage Statistics</cite></a> » <small class="plainlinks cachelinks">[<a rel="nofollow" class="external text" href="https://web.archive.org/web/20200708065729/https://clincalc.com/DrugStats/Drugs/Carisoprodol">archive du <time class="nowrap" datetime="2020-07-08" data-sort-value="2020-07-08">8 juillet 2020</time></a>]</small></span>, <span class="italique">ClinCalc</span> <small style="line-height:1em;">(consulté le <time class="nowrap" datetime="2020-04-11" data-sort-value="2020-04-11">11 avril 2020</time>)</small></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Liens_externes">Liens externes</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Carisoprodol&veaction=edit&section=6" title="Modifier la section : Liens externes" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Carisoprodol&action=edit&section=6" title="Modifier le code source de la section : Liens externes"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p class="mw-empty-elt"> </p> <ul><li class="mw-empty-elt"></li> <li><span class="liste-horizontale noarchive"><span class="wd_identifiers">Ressources relatives à la santé<span class="noprint wikidata-linkback skin-invert"><span class="mw-valign-baseline noviewer" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q416905?uselang=fr#identifiers" 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