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Na–K–Cl cotransporter - Wikipedia
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vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Kinetics"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Kinetics</span> </div> </a> <ul id="toc-Kinetics-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-See_also" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#See_also"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>See also</span> </div> </a> <ul id="toc-See_also-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>References</span> </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-External_links" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a 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cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Toggle the table of contents</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Na–K–Cl cotransporter</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. Available in 7 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-7" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">7 languages</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Na-K-2Cl-Cotransporter" title="Na-K-2Cl-Cotransporter – German" lang="de" hreflang="de" data-title="Na-K-2Cl-Cotransporter" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Cotransportador_Na-K-2Cl" title="Cotransportador Na-K-2Cl – Spanish" lang="es" hreflang="es" data-title="Cotransportador Na-K-2Cl" data-language-autonym="Español" data-language-local-name="Spanish" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Cotrasportatore_Na-K-Cl" title="Cotrasportatore Na-K-Cl – Italian" lang="it" hreflang="it" data-title="Cotrasportatore Na-K-Cl" data-language-autonym="Italiano" data-language-local-name="Italian" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Na-K-Cl_kotransporter" title="Na-K-Cl kotransporter – Serbian" lang="sr" hreflang="sr" data-title="Na-K-Cl kotransporter" data-language-autonym="Српски / srpski" data-language-local-name="Serbian" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Na-K-Cl_kotransporter" title="Na-K-Cl kotransporter – Serbo-Croatian" lang="sh" hreflang="sh" data-title="Na-K-Cl kotransporter" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="Serbo-Croatian" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/Na-K-Cl_%D0%BA%D0%BE%D1%82%D1%80%D0%B0%D0%BD%D1%81%D0%BF%D0%BE%D1%80%D1%82%D0%B5%D1%80" title="Na-K-Cl котранспортер – Ukrainian" lang="uk" hreflang="uk" data-title="Na-K-Cl котранспортер" data-language-autonym="Українська" data-language-local-name="Ukrainian" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E9%88%89%E9%89%80%E6%B0%AF%E5%85%B1%E8%BD%89%E9%81%8B%E8%9B%8B%E7%99%BD" title="鈉鉀氯共轉運蛋白 – Chinese" lang="zh" hreflang="zh" data-title="鈉鉀氯共轉運蛋白" data-language-autonym="中文" data-language-local-name="Chinese" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q2580288#sitelinks-wikipedia" title="Edit interlanguage links" class="wbc-editpage">Edit links</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Namespaces"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a 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</div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Page tools"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Appearance"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Appearance</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">hide</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">From Wikipedia, the free encyclopedia</div> </div> <div id="contentSub"><div id="mw-content-subtitle"><span class="mw-redirectedfrom">(Redirected from <a href="/w/index.php?title=Na-K-Cl_cotransporter&redirect=no" class="mw-redirect" title="Na-K-Cl cotransporter">Na-K-Cl cotransporter</a>)</span></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Group of transport proteins</div> <style data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox"><tbody><tr><th colspan="2" class="infobox-above">solute carrier family 12 member 1</th></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Identifiers</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3">Symbol</th><td class="infobox-data" style="background-color: #eee">SLC12A1</td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3">Alt. symbols</th><td class="infobox-data" style="background-color: #eee">NKCC2</td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/National_Center_for_Biotechnology_Information#Gene" title="National Center for Biotechnology Information">NCBI gene</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/gene?cmd=retrieve&dopt=default&list_uids=6557&rn=1">6557</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/HUGO_Gene_Nomenclature_Committee" title="HUGO Gene Nomenclature Committee">HGNC</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:10910">10910</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Online_Mendelian_Inheritance_in_Man" title="Online Mendelian Inheritance in Man">OMIM</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://omim.org/entry/600839">600839</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/HomoloGene" title="HomoloGene">Orthologs</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/homologene?cmd=Retrieve&dopt=HomoloGene&list_uids=286">286</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/RefSeq" title="RefSeq">RefSeq</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/protein/NM_000338">NM_000338</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Swiss-Prot" class="mw-redirect" title="Swiss-Prot">UniProt</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/Q13621">Q13621</a></td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Other data</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Locus</a></th><td class="infobox-data" style="background-color: #eee"><a href="/wiki/Chromosome_15_(human)" class="mw-redirect" title="Chromosome 15 (human)">Chr. 15</a> <i><a rel="nofollow" class="external text" href="https://omim.org/search/?index=geneMap&search=15q21.1">q21.1</a></i></td></tr><tr><td colspan="2" class="infobox-full-data" style="background-color: #eee"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><table class="infobox mw-collapsible mw-collapsed" style="float:none; clear:none; margin:0; border-width:0; border-collapse:collapse; text-align:left; width:100%"><tbody><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Search for</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;">Structures</th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="https://swissmodel.expasy.org/repository/uniprot/Q13621">Swiss-model</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;">Domains</th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/interpro/protein/Q13621">InterPro</a></td></tr></tbody></table></td></tr></tbody></table> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><table class="infobox"><tbody><tr><th colspan="2" class="infobox-above">solute carrier family 12 member 2</th></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Identifiers</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3">Symbol</th><td class="infobox-data" style="background-color: #eee">SLC12A2</td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3">Alt. symbols</th><td class="infobox-data" style="background-color: #eee">NKCC1</td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/National_Center_for_Biotechnology_Information#Gene" title="National Center for Biotechnology Information">NCBI gene</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/gene?cmd=retrieve&dopt=default&list_uids=6558&rn=1">6558</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/HUGO_Gene_Nomenclature_Committee" title="HUGO Gene Nomenclature Committee">HGNC</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:10911">10911</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Online_Mendelian_Inheritance_in_Man" title="Online Mendelian Inheritance in Man">OMIM</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://omim.org/entry/600840">600840</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/HomoloGene" title="HomoloGene">Orthologs</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/homologene?cmd=Retrieve&dopt=HomoloGene&list_uids=20283">20283</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/RefSeq" title="RefSeq">RefSeq</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/protein/NM_001046">NM_001046</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Swiss-Prot" class="mw-redirect" title="Swiss-Prot">UniProt</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/P55011">P55011</a></td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Other data</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Locus</a></th><td class="infobox-data" style="background-color: #eee"><a href="/wiki/Chromosome_5_(human)" class="mw-redirect" title="Chromosome 5 (human)">Chr. 5</a> <i><a rel="nofollow" class="external text" href="https://omim.org/search/?index=geneMap&search=5q23.3">q23.3</a></i></td></tr><tr><td colspan="2" class="infobox-full-data" style="background-color: #eee"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><table class="infobox mw-collapsible mw-collapsed" style="float:none; clear:none; margin:0; border-width:0; border-collapse:collapse; text-align:left; width:100%"><tbody><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Search for</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;">Structures</th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="https://swissmodel.expasy.org/repository/uniprot/P55011">Swiss-model</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;">Domains</th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/interpro/protein/P55011">InterPro</a></td></tr></tbody></table></td></tr></tbody></table> <p>The <b>Na–K–Cl <a href="/wiki/Cotransporter" title="Cotransporter">cotransporter</a></b> (<b>NKCC</b>) is a <a href="/wiki/Transport_protein" title="Transport protein">transport protein</a> that aids in the <a href="/wiki/Secondary_active_transport" class="mw-redirect" title="Secondary active transport">secondary active transport</a> of <a href="/wiki/Sodium" title="Sodium">sodium</a>, <a href="/wiki/Potassium" title="Potassium">potassium</a>, and <a href="/wiki/Chloride" title="Chloride">chloride</a> into <a href="/wiki/Cell_(biology)" title="Cell (biology)">cells</a>.<sup id="cite_ref-pmid7943281_1-0" class="reference"><a href="#cite_note-pmid7943281-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> In humans there are two isoforms of this <a href="/wiki/Membrane_transport_protein" title="Membrane transport protein">membrane transport protein</a>, <b>NKCC1</b> and <b>NKCC2</b>, encoded by two different <a href="/wiki/Gene" title="Gene">genes</a> (<i>SLC12A2</i> and <i>SLC12A1</i> respectively). Two isoforms of the NKCC1/Slc12a2 gene result from keeping (isoform 1) or skipping (isoform 2) exon 21 in the final gene product.<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p><p>NKCC1 is widely distributed throughout the human body; it has important functions in <a href="/wiki/Organ_(anatomy)" class="mw-redirect" title="Organ (anatomy)">organs</a> that <a href="/wiki/Secretion" title="Secretion">secrete</a> fluids. It is found specifically in the <a href="/wiki/Kidney" title="Kidney">kidney</a>, where it extracts sodium, potassium, and chloride from the <a href="/wiki/Urine" title="Urine">urine</a> so they can be <a href="/wiki/Reabsorption" title="Reabsorption">reabsorbed</a> into the <a href="/wiki/Blood" title="Blood">blood</a>. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Function">Function</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Na%E2%80%93K%E2%80%93Cl_cotransporter&action=edit&section=1" title="Edit section: Function"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>NKCC proteins are <a href="/wiki/Membrane_transport_protein" title="Membrane transport protein">membrane transport proteins</a> that transport <a href="/wiki/Sodium" title="Sodium">sodium</a> (Na), <a href="/wiki/Potassium" title="Potassium">potassium</a> (K), and <a href="/wiki/Chloride" title="Chloride">chloride</a> (Cl) ions across the <a href="/wiki/Cell_membrane" title="Cell membrane">cell membrane</a>. Because they move each solute in the same direction, they are considered <a href="/wiki/Symporter" title="Symporter">symporters</a>. They maintain electroneutrality by moving two positively charged solutes (sodium and potassium) alongside two parts of a negatively charged solute (chloride). Thus the <a href="/wiki/Stoichiometry" title="Stoichiometry">stoichiometry</a> of the transported solutes is 1Na:1K:2Cl. Although <a href="/wiki/Squid_giant_axon" title="Squid giant axon">squid giant axons</a> are the only notable exception with a stoichiometry of 2Na:1K:3Cl, electroneutrality across the protein transporter is still maintained.<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="NKCC1">NKCC1</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Na%E2%80%93K%E2%80%93Cl_cotransporter&action=edit&section=2" title="Edit section: NKCC1"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>NKCC1 is widely distributed throughout the body, especially in organs that <a href="/wiki/Secretion" title="Secretion">secrete</a> fluids, called <a href="/wiki/Exocrine_gland" title="Exocrine gland">exocrine glands</a>.<sup id="cite_ref-pmid10845101_4-0" class="reference"><a href="#cite_note-pmid10845101-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> In cells of these organs, NKCC1 is commonly found in the <a href="/wiki/Basolateral_membrane" class="mw-redirect" title="Basolateral membrane">basolateral membrane</a>,<sup id="cite_ref-pmid10369265_5-0" class="reference"><a href="#cite_note-pmid10369265-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> the part of the <a href="/wiki/Cell_membrane" title="Cell membrane">cell membrane</a> closest to the <a href="/wiki/Blood_vessel" title="Blood vessel">blood vessels</a>. Its basolateral location gives NKCC1 the ability to transport sodium, potassium, and chloride from the blood into the cell. Other transporters assist in the movement of these solutes out of the cell through its apical surface. The end result is that solutes from the blood, particularly chloride, are secreted into the lumen of these exocrine glands, increasing the luminal <a href="/wiki/Osmolality" class="mw-redirect" title="Osmolality">concentration of solutes</a> and causing water to be secreted by <a href="/wiki/Osmosis" title="Osmosis">osmosis</a>. </p><p>In addition to exocrine glands, NKCC1 is necessary for establishing the potassium-rich <a href="/wiki/Endolymph" title="Endolymph">endolymph</a> that bathes part of the <a href="/wiki/Cochlea" title="Cochlea">cochlea</a>, an organ necessary for hearing. Inhibition of NKCC1, as with <a href="/wiki/Furosemide" title="Furosemide">furosemide</a> or other <a href="/wiki/Loop_diuretic" title="Loop diuretic">loop diuretics</a>, can result in <a href="/wiki/Deafness" title="Deafness">deafness</a>.<sup id="cite_ref-pmid10369265_5-1" class="reference"><a href="#cite_note-pmid10369265-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p><p>NKCC1 is also expressed in many regions of the <a href="/wiki/Brain" title="Brain">brain</a> during early development, but not in adulthood.<sup id="cite_ref-pmid16227993_6-0" class="reference"><a href="#cite_note-pmid16227993-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> This change in NKCC1 presence seems to be responsible for altering responses to the neurotransmitters <a href="/wiki/GABA" title="GABA">GABA</a> and <a href="/wiki/Glycine" title="Glycine">glycine</a> from excitatory to inhibitory, which was suggested to be important for early neuronal development. As long as NKCC1 transporters are predominantly active, internal chloride concentrations in neurons is raised in comparison with mature chloride concentrations, which is important for GABA and glycine responses, as respective ligand-gated anion channels are permeable to chloride. With higher internal chloride concentrations, outward driving force for this ions increases, and thus channel opening leads to chloride leaving the cell, thereby depolarizing it. Put another way, increasing internal chloride concentration increases the <a href="/wiki/Reversal_potential" title="Reversal potential">reversal potential</a> for chloride, given by the <a href="/wiki/Nernst_equation" title="Nernst equation">Nernst equation</a>. Later in development expression of NKCC1 is reduced, while expression of a <a href="/wiki/KCC2" class="mw-redirect" title="KCC2">KCC2</a> <a href="/wiki/K-Cl_cotransporter" class="mw-redirect" title="K-Cl cotransporter">K-Cl cotransporter</a> increased, thus bringing internal chloride concentration in neurons down to adult values.<sup id="cite_ref-pmid17928584_7-0" class="reference"><a href="#cite_note-pmid17928584-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="NKCC2">NKCC2</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Na%E2%80%93K%E2%80%93Cl_cotransporter&action=edit&section=3" title="Edit section: NKCC2"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>NKCC2 is specifically found in cells of the <a href="/wiki/Thick_ascending_limb_of_the_loop_of_Henle" class="mw-redirect" title="Thick ascending limb of the loop of Henle">thick ascending limb of the loop of Henle</a> and the <a href="/wiki/Macula_densa" title="Macula densa">macula densa</a> in <a href="/wiki/Nephron" title="Nephron">nephrons</a>, the basic functional units of the <a href="/wiki/Kidney" title="Kidney">kidney</a>. Within these cells, NKCC2 resides in the <a href="/wiki/Apical_membrane" class="mw-redirect" title="Apical membrane">apical membrane</a><sup id="cite_ref-pmid8572179_8-0" class="reference"><a href="#cite_note-pmid8572179-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> abutting the nephron's <a href="/wiki/Lumen_(anatomy)" title="Lumen (anatomy)">lumen</a>, which is the hollow space containing <a href="/wiki/Urine" title="Urine">urine</a>. It thus serves both in sodium absorption and in <a href="/wiki/Tubuloglomerular_feedback" title="Tubuloglomerular feedback">tubuloglomerular feedback</a>. </p><p>The thick ascending limb of the loop of Henle begins at the deeper portion of the renal outer medulla. Here, the urine has a relatively high concentration of sodium. As urine moves towards the more superficial portion of the thick ascending limb, NKCC2 is the major transport protein by which sodium is reabsorbed from the urine. This outward movement of sodium and the lack of water permeability in the thick ascending limb, creates a more diluted urine.<sup id="cite_ref-pmid18982348_9-0" class="reference"><a href="#cite_note-pmid18982348-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> According to the stoichiometry outlined above, each sodium ion reabsorbed brings one potassium ion and two chloride ions. Sodium goes on to be reabsorbed into the <a href="/wiki/Blood" title="Blood">blood</a>, where it contributes to the maintenance of <a href="/wiki/Blood_pressure" title="Blood pressure">blood pressure</a>. </p><p><a href="/wiki/Furosemide" title="Furosemide">Furosemide</a> and other <a href="/wiki/Loop_diuretic" title="Loop diuretic">loop diuretics</a> inhibit the activity of NKCC2, thereby impairing sodium reabsorption in the thick ascending limb of the loop of Henle. The action of these <a href="/wiki/Loop_diuretic" title="Loop diuretic">loop diuretics</a> also reduces potassium reabsorption through the NKCC2 cotransporter and consequently increases tubular flow rate which enhances potassium secretion and emphasises the hypokalaemic effect. </p><p>Impaired sodium reabsorption increases diuresis by three mechanisms: </p> <ol><li>Increases the amount of active <a href="/wiki/Osmolyte" title="Osmolyte">osmolytes</a> in urine by decreasing absorption of sodium</li> <li>Erases the papillar gradient</li> <li>Inhibits <a href="/wiki/Tubuloglomerular_feedback" title="Tubuloglomerular feedback">tubuloglomerular feedback</a></li></ol> <p><a href="/wiki/Loop_diuretic" title="Loop diuretic">Loop diuretics</a> therefore ultimately result in decreased blood pressure. </p><p>The hormone <a href="/wiki/Vasopressin" title="Vasopressin">vasopressin</a> also stimulates the activity of NKCC2. Vasopressin stimulates sodium chloride reabsorption in the thick ascending limb of the nephron by activating signaling pathways. Vasopressin increases the traffic of NKCC2 to the membrane and phosphorylates some <a href="/wiki/Serine" title="Serine">serine</a> and <a href="/wiki/Threonine" title="Threonine">threonine</a> sites on the cytoplasmic N-terminal of the NKCC2 located in the membrane, increasing its activity. Increased NKCC2 activity aids in water reabsorption in the collecting duct through <a href="/wiki/Aquaporin_2" class="mw-redirect" title="Aquaporin 2">aquaporin 2</a> channels by creating a hypo-osmotic filtrate.<sup id="cite_ref-pmid23123217_10-0" class="reference"><a href="#cite_note-pmid23123217-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid21900458_11-0" class="reference"><a href="#cite_note-pmid21900458-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Genetics">Genetics</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Na%E2%80%93K%E2%80%93Cl_cotransporter&action=edit&section=4" title="Edit section: Genetics"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>NKCC1 and NKCC2 are encoded by <a href="/wiki/Gene" title="Gene">genes</a> on the <a href="/wiki/Locus_(genetics)" title="Locus (genetics)">long arms</a> of <a href="/wiki/Chromosome_5" title="Chromosome 5">chromosomes 5</a><sup id="cite_ref-pmid7629105_12-0" class="reference"><a href="#cite_note-pmid7629105-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> and <a href="/wiki/Chromosome_15" title="Chromosome 15">15</a>,<sup id="cite_ref-pmid8640224_13-0" class="reference"><a href="#cite_note-pmid8640224-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> respectively. A loss of function mutation of NKCC2 produces <a href="/wiki/Bartter_syndrome" title="Bartter syndrome">Bartter syndrome</a>, an autosomal recessive disorder characterized by hypokalemic <a href="/wiki/Metabolic_alkalosis" title="Metabolic alkalosis">metabolic alkalosis</a> with normal to low blood pressure.<sup id="cite_ref-pmid8640224_13-1" class="reference"><a href="#cite_note-pmid8640224-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Kinetics">Kinetics</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Na%E2%80%93K%E2%80%93Cl_cotransporter&action=edit&section=5" title="Edit section: Kinetics"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The <a href="/wiki/Energy" title="Energy">energy</a> required to move solutes across the cell membrane is provided by the <a href="/wiki/Electrochemical_gradient" title="Electrochemical gradient">electrochemical gradient</a> of sodium. Sodium's electrochemical gradient is established by the <a href="/wiki/Na/K-ATPase" class="mw-redirect" title="Na/K-ATPase">Na/K-ATPase</a>, which is an <a href="/wiki/Adenosine_triphosphate" title="Adenosine triphosphate">ATP</a>-dependent <a href="/wiki/Enzyme" title="Enzyme">enzyme</a>. Since NKCC proteins use sodium's gradient, their activity is indirectly dependent on ATP; for this reason, NKCC proteins are said to move solutes by way of <a href="/wiki/Secondary_active_transport" class="mw-redirect" title="Secondary active transport">secondary active transport</a>. There are three isoforms of NKCC2 created by alternative splicing (NKCC2A, B and F). Each one of these isoforms is expressed at different portions of the thick ascending limb and they have different affinity for sodium that correlates with its localization. The isoform F is more predominant in the deeper portion of the thick ascending limb, where the sodium concentration is very high. NKCC2F is the isoform with the lowest affinity for sodium and this allows the cotransporter to work at this sodium rich environment. Conversely, NKCC2B is expressed at the more superficial portion of the thick ascending limb and the macula densa, and it has the highest affinity for sodium. This permits NKCC2B to function in this sodium-depleted environment without saturating. The NKCC2A isoform shows an intermediate distribution and affinity for sodium.<sup id="cite_ref-pmid11790783_14-0" class="reference"><a href="#cite_note-pmid11790783-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> In this way, NKCC2 is able to function properly along the range of sodium concentrations found along the thick ascending limb. </p> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Na%E2%80%93K%E2%80%93Cl_cotransporter&action=edit&section=6" title="Edit section: See also"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Co-transport" class="mw-redirect" title="Co-transport">Cotransport</a></li> <li><a href="/wiki/Cotransporter" title="Cotransporter">Cotransporter</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Na%E2%80%93K%E2%80%93Cl_cotransporter&action=edit&section=7" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist reflist-columns references-column-width reflist-columns-2"> <ol class="references"> <li id="cite_note-pmid7943281-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid7943281_1-0">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFHaas1994" class="citation journal cs1">Haas M (October 1994). "The Na-K-Cl cotransporters". <i>Am. J. Physiol</i>. <b>267</b> (4 Pt 1): C869–85. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1152%2Fajpcell.1994.267.4.C869">10.1152/ajpcell.1994.267.4.C869</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7943281">7943281</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:22680398">22680398</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Am.+J.+Physiol.&rft.atitle=The+Na-K-Cl+cotransporters&rft.volume=267&rft.issue=4+Pt+1&rft.pages=C869-85&rft.date=1994-10&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A22680398%23id-name%3DS2CID&rft_id=info%3Apmid%2F7943281&rft_id=info%3Adoi%2F10.1152%2Fajpcell.1994.267.4.C869&rft.aulast=Haas&rft.aufirst=M&rfr_id=info%3Asid%2Fen.wikipedia.org%3ANa%E2%80%93K%E2%80%93Cl+cotransporter" class="Z3988"></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHebertMount,_DBGamba,_G2004" class="citation journal cs1">Hebert, SC; Mount, DB; Gamba, G (February 2004). "Molecular physiology of cation-coupled Cl<sup>−</sup> cotransport: the SLC12 family". <i>Pflügers Archiv: European Journal of Physiology</i>. <b>447</b> (5): 580–593. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2Fs00424-003-1066-3">10.1007/s00424-003-1066-3</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12739168">12739168</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:21998913">21998913</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Pfl%C3%BCgers+Archiv%3A+European+Journal+of+Physiology&rft.atitle=Molecular+physiology+of+cation-coupled+Cl%3Csup%3E%E2%88%92%3C%2Fsup%3E+cotransport%3A+the+SLC12+family.&rft.volume=447&rft.issue=5&rft.pages=580-593&rft.date=2004-02&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A21998913%23id-name%3DS2CID&rft_id=info%3Apmid%2F12739168&rft_id=info%3Adoi%2F10.1007%2Fs00424-003-1066-3&rft.aulast=Hebert&rft.aufirst=SC&rft.au=Mount%2C+DB&rft.au=Gamba%2C+G&rfr_id=info%3Asid%2Fen.wikipedia.org%3ANa%E2%80%93K%E2%80%93Cl+cotransporter" class="Z3988"></span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFRussell2000" class="citation journal cs1">Russell, J. M. (January 2000). "Sodium-potassium-chloride cotransport". <i>Physiological Reviews</i>. <b>80</b> (1): 211–276. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1152%2Fphysrev.2000.80.1.211">10.1152/physrev.2000.80.1.211</a>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a> <a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/0031-9333">0031-9333</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10617769">10617769</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:8909659">8909659</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Physiological+Reviews&rft.atitle=Sodium-potassium-chloride+cotransport&rft.volume=80&rft.issue=1&rft.pages=211-276&rft.date=2000-01&rft.issn=0031-9333&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A8909659%23id-name%3DS2CID&rft_id=info%3Apmid%2F10617769&rft_id=info%3Adoi%2F10.1152%2Fphysrev.2000.80.1.211&rft.aulast=Russell&rft.aufirst=J.+M.&rfr_id=info%3Asid%2Fen.wikipedia.org%3ANa%E2%80%93K%E2%80%93Cl+cotransporter" class="Z3988"></span></span> </li> <li id="cite_note-pmid10845101-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid10845101_4-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHaasForbush2000" class="citation journal cs1">Haas M, Forbush B (2000). "The Na-K-Cl cotransporter of secretory epithelia". <i>Annu. Rev. Physiol</i>. <b>62</b>: 515–34. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1146%2Fannurev.physiol.62.1.515">10.1146/annurev.physiol.62.1.515</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10845101">10845101</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Annu.+Rev.+Physiol.&rft.atitle=The+Na-K-Cl+cotransporter+of+secretory+epithelia&rft.volume=62&rft.pages=515-34&rft.date=2000&rft_id=info%3Adoi%2F10.1146%2Fannurev.physiol.62.1.515&rft_id=info%3Apmid%2F10845101&rft.aulast=Haas&rft.aufirst=M&rft.au=Forbush%2C+B&rfr_id=info%3Asid%2Fen.wikipedia.org%3ANa%E2%80%93K%E2%80%93Cl+cotransporter" class="Z3988"></span></span> </li> <li id="cite_note-pmid10369265-5"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid10369265_5-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid10369265_5-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDelpireLuEnglandDull1999" class="citation journal cs1">Delpire E, Lu J, England R, Dull C, Thorne T (June 1999). "Deafness and imbalance associated with inactivation of the secretory Na-K-2Cl co-transporter". <i>Nat. Genet</i>. <b>22</b> (2): 192–5. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2F9713">10.1038/9713</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10369265">10369265</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:23779936">23779936</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nat.+Genet.&rft.atitle=Deafness+and+imbalance+associated+with+inactivation+of+the+secretory+Na-K-2Cl+co-transporter&rft.volume=22&rft.issue=2&rft.pages=192-5&rft.date=1999-06&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A23779936%23id-name%3DS2CID&rft_id=info%3Apmid%2F10369265&rft_id=info%3Adoi%2F10.1038%2F9713&rft.aulast=Delpire&rft.aufirst=E&rft.au=Lu%2C+J&rft.au=England%2C+R&rft.au=Dull%2C+C&rft.au=Thorne%2C+T&rfr_id=info%3Asid%2Fen.wikipedia.org%3ANa%E2%80%93K%E2%80%93Cl+cotransporter" class="Z3988"></span></span> </li> <li id="cite_note-pmid16227993-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid16227993_6-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDzhalaTalosSdrullaBrumback2005" class="citation journal cs1">Dzhala VI, Talos DM, Sdrulla DA, Brumback AC, Mathews GC, Benke TA, Delpire E, Jensen FE, Staley KJ (November 2005). "NKCC1 transporter facilitates seizures in the developing brain". <i>Nat. Med</i>. <b>11</b> (11): 1205–13. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnm1301">10.1038/nm1301</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16227993">16227993</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:25348736">25348736</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nat.+Med.&rft.atitle=NKCC1+transporter+facilitates+seizures+in+the+developing+brain&rft.volume=11&rft.issue=11&rft.pages=1205-13&rft.date=2005-11&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A25348736%23id-name%3DS2CID&rft_id=info%3Apmid%2F16227993&rft_id=info%3Adoi%2F10.1038%2Fnm1301&rft.aulast=Dzhala&rft.aufirst=VI&rft.au=Talos%2C+DM&rft.au=Sdrulla%2C+DA&rft.au=Brumback%2C+AC&rft.au=Mathews%2C+GC&rft.au=Benke%2C+TA&rft.au=Delpire%2C+E&rft.au=Jensen%2C+FE&rft.au=Staley%2C+KJ&rfr_id=info%3Asid%2Fen.wikipedia.org%3ANa%E2%80%93K%E2%80%93Cl+cotransporter" class="Z3988"></span></span> </li> <li id="cite_note-pmid17928584-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid17928584_7-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBen-AriGaiarsaTyzioKhazipov2007" class="citation journal cs1">Ben-Ari Y, Gaiarsa JL, Tyzio R, Khazipov R (October 2007). "GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations". <i>Physiol. Rev</i>. <b>87</b> (4): 1215–84. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1152%2Fphysrev.00017.2006">10.1152/physrev.00017.2006</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17928584">17928584</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Physiol.+Rev.&rft.atitle=GABA%3A+a+pioneer+transmitter+that+excites+immature+neurons+and+generates+primitive+oscillations&rft.volume=87&rft.issue=4&rft.pages=1215-84&rft.date=2007-10&rft_id=info%3Adoi%2F10.1152%2Fphysrev.00017.2006&rft_id=info%3Apmid%2F17928584&rft.aulast=Ben-Ari&rft.aufirst=Y&rft.au=Gaiarsa%2C+JL&rft.au=Tyzio%2C+R&rft.au=Khazipov%2C+R&rfr_id=info%3Asid%2Fen.wikipedia.org%3ANa%E2%80%93K%E2%80%93Cl+cotransporter" class="Z3988"></span></span> </li> <li id="cite_note-pmid8572179-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid8572179_8-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLytleXuBiemesderferForbush1995" class="citation journal cs1">Lytle C, Xu JC, Biemesderfer D, Forbush B (December 1995). "Distribution and diversity of Na-K-Cl cotransport proteins: a study with monoclonal antibodies". <i>Am. J. Physiol</i>. <b>269</b> (6 Pt 1): C1496–505. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1152%2Fajpcell.1995.269.6.C1496">10.1152/ajpcell.1995.269.6.C1496</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8572179">8572179</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Am.+J.+Physiol.&rft.atitle=Distribution+and+diversity+of+Na-K-Cl+cotransport+proteins%3A+a+study+with+monoclonal+antibodies&rft.volume=269&rft.issue=6+Pt+1&rft.pages=C1496-505&rft.date=1995-12&rft_id=info%3Adoi%2F10.1152%2Fajpcell.1995.269.6.C1496&rft_id=info%3Apmid%2F8572179&rft.aulast=Lytle&rft.aufirst=C&rft.au=Xu%2C+JC&rft.au=Biemesderfer%2C+D&rft.au=Forbush%2C+B&rfr_id=info%3Asid%2Fen.wikipedia.org%3ANa%E2%80%93K%E2%80%93Cl+cotransporter" class="Z3988"></span></span> </li> <li id="cite_note-pmid18982348-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid18982348_9-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGambaFriedman2009" class="citation journal cs1">Gamba G, Friedman PA (May 2009). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584568">"Thick ascending limb: the Na(+):K (+):2Cl (-) co-transporter, NKCC2, and the calcium-sensing receptor, CaSR"</a>. <i>Pflügers Arch</i>. <b>458</b> (1): 61–76. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2Fs00424-008-0607-1">10.1007/s00424-008-0607-1</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584568">3584568</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18982348">18982348</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Pfl%C3%BCgers+Arch&rft.atitle=Thick+ascending+limb%3A+the+Na%28%2B%29%3AK+%28%2B%29%3A2Cl+%28-%29+co-transporter%2C+NKCC2%2C+and+the+calcium-sensing+receptor%2C+CaSR&rft.volume=458&rft.issue=1&rft.pages=61-76&rft.date=2009-05&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3584568%23id-name%3DPMC&rft_id=info%3Apmid%2F18982348&rft_id=info%3Adoi%2F10.1007%2Fs00424-008-0607-1&rft.aulast=Gamba&rft.aufirst=G&rft.au=Friedman%2C+PA&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3584568&rfr_id=info%3Asid%2Fen.wikipedia.org%3ANa%E2%80%93K%E2%80%93Cl+cotransporter" class="Z3988"></span></span> </li> <li id="cite_note-pmid23123217-10"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid23123217_10-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFRiegTangUchidaHammond2013" class="citation journal cs1">Rieg T, Tang T, Uchida S, Hammond HK, Fenton RA, Vallon V (January 2013). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532715">"Adenylyl cyclase 6 enhances NKCC2 expression and mediates vasopressin-induced phosphorylation of NKCC2 and NCC"</a>. <i>Am. J. Pathol</i>. <b>182</b> (1): 96–106. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.ajpath.2012.09.014">10.1016/j.ajpath.2012.09.014</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532715">3532715</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23123217">23123217</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Am.+J.+Pathol.&rft.atitle=Adenylyl+cyclase+6+enhances+NKCC2+expression+and+mediates+vasopressin-induced+phosphorylation+of+NKCC2+and+NCC&rft.volume=182&rft.issue=1&rft.pages=96-106&rft.date=2013-01&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3532715%23id-name%3DPMC&rft_id=info%3Apmid%2F23123217&rft_id=info%3Adoi%2F10.1016%2Fj.ajpath.2012.09.014&rft.aulast=Rieg&rft.aufirst=T&rft.au=Tang%2C+T&rft.au=Uchida%2C+S&rft.au=Hammond%2C+HK&rft.au=Fenton%2C+RA&rft.au=Vallon%2C+V&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3532715&rfr_id=info%3Asid%2Fen.wikipedia.org%3ANa%E2%80%93K%E2%80%93Cl+cotransporter" class="Z3988"></span></span> </li> <li id="cite_note-pmid21900458-11"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid21900458_11-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAresCaceresOrtiz2011" class="citation journal cs1">Ares GR, Caceres PS, Ortiz PA (December 2011). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233874">"Molecular regulation of NKCC2 in the thick ascending limb"</a>. <i>Am. J. Physiol. Renal Physiol</i>. <b>301</b> (6): F1143–59. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1152%2Fajprenal.00396.2011">10.1152/ajprenal.00396.2011</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233874">3233874</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/21900458">21900458</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Am.+J.+Physiol.+Renal+Physiol.&rft.atitle=Molecular+regulation+of+NKCC2+in+the+thick+ascending+limb&rft.volume=301&rft.issue=6&rft.pages=F1143-59&rft.date=2011-12&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3233874%23id-name%3DPMC&rft_id=info%3Apmid%2F21900458&rft_id=info%3Adoi%2F10.1152%2Fajprenal.00396.2011&rft.aulast=Ares&rft.aufirst=GR&rft.au=Caceres%2C+PS&rft.au=Ortiz%2C+PA&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3233874&rfr_id=info%3Asid%2Fen.wikipedia.org%3ANa%E2%80%93K%E2%80%93Cl+cotransporter" class="Z3988"></span></span> </li> <li id="cite_note-pmid7629105-12"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid7629105_12-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPayneXuHaasLytle1995" class="citation journal cs1">Payne JA, Xu JC, Haas M, Lytle CY, Ward D, Forbush B (July 1995). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.270.30.17977">"Primary structure, functional expression, and chromosomal localization of the bumetanide-sensitive Na-K-Cl cotransporter in human colon"</a>. <i>J. Biol. Chem</i>. <b>270</b> (30): 17977–85. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.270.30.17977">10.1074/jbc.270.30.17977</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7629105">7629105</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Biol.+Chem.&rft.atitle=Primary+structure%2C+functional+expression%2C+and+chromosomal+localization+of+the+bumetanide-sensitive+Na-K-Cl+cotransporter+in+human+colon&rft.volume=270&rft.issue=30&rft.pages=17977-85&rft.date=1995-07&rft_id=info%3Adoi%2F10.1074%2Fjbc.270.30.17977&rft_id=info%3Apmid%2F7629105&rft.aulast=Payne&rft.aufirst=JA&rft.au=Xu%2C+JC&rft.au=Haas%2C+M&rft.au=Lytle%2C+CY&rft.au=Ward%2C+D&rft.au=Forbush%2C+B&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.270.30.17977&rfr_id=info%3Asid%2Fen.wikipedia.org%3ANa%E2%80%93K%E2%80%93Cl+cotransporter" class="Z3988"></span></span> </li> <li id="cite_note-pmid8640224-13"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid8640224_13-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid8640224_13-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSimonKaretHamdanDiPietro1996" class="citation journal cs1">Simon DB, Karet FE, Hamdan JM, DiPietro A, Sanjad SA, Lifton RP (June 1996). "Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2". <i>Nat. Genet</i>. <b>13</b> (2): 183–8. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fng0696-183">10.1038/ng0696-183</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8640224">8640224</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:42296304">42296304</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nat.+Genet.&rft.atitle=Bartter%27s+syndrome%2C+hypokalaemic+alkalosis+with+hypercalciuria%2C+is+caused+by+mutations+in+the+Na-K-2Cl+cotransporter+NKCC2&rft.volume=13&rft.issue=2&rft.pages=183-8&rft.date=1996-06&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A42296304%23id-name%3DS2CID&rft_id=info%3Apmid%2F8640224&rft_id=info%3Adoi%2F10.1038%2Fng0696-183&rft.aulast=Simon&rft.aufirst=DB&rft.au=Karet%2C+FE&rft.au=Hamdan%2C+JM&rft.au=DiPietro%2C+A&rft.au=Sanjad%2C+SA&rft.au=Lifton%2C+RP&rfr_id=info%3Asid%2Fen.wikipedia.org%3ANa%E2%80%93K%E2%80%93Cl+cotransporter" class="Z3988"></span></span> </li> <li id="cite_note-pmid11790783-14"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid11790783_14-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPlataMeadeVazquezHebert2002" class="citation journal cs1">Plata C, Meade P, Vazquez N, Hebert SC, Gamba G (Mar 2002). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M110442200">"Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms"</a>. <i>J. Biol. Chem</i>. <b>277</b> (13): 11004–12. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M110442200">10.1074/jbc.M110442200</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11790783">11790783</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Biol.+Chem.&rft.atitle=Functional+properties+of+the+apical+Na%2B-K%2B-2Cl-+cotransporter+isoforms&rft.volume=277&rft.issue=13&rft.pages=11004-12&rft.date=2002-03&rft_id=info%3Adoi%2F10.1074%2Fjbc.M110442200&rft_id=info%3Apmid%2F11790783&rft.aulast=Plata&rft.aufirst=C&rft.au=Meade%2C+P&rft.au=Vazquez%2C+N&rft.au=Hebert%2C+SC&rft.au=Gamba%2C+G&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.M110442200&rfr_id=info%3Asid%2Fen.wikipedia.org%3ANa%E2%80%93K%E2%80%93Cl+cotransporter" class="Z3988"></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Na%E2%80%93K%E2%80%93Cl_cotransporter&action=edit&section=8" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> 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aria-labelledby="Membrane_transport_protein:_ion_pumps,_ATPases_/_ATP_synthase_(TC_3A2-3A3)" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e7dcc3"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><style data-mw-deduplicate="TemplateStyles:r1239400231">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}html.skin-theme-clientpref-night .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:ATPase" title="Template:ATPase"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:ATPase" title="Template talk:ATPase"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:ATPase" title="Special:EditPage/Template:ATPase"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Membrane_transport_protein:_ion_pumps,_ATPases_/_ATP_synthase_(TC_3A2-3A3)" style="font-size:114%;margin:0 4em"><a href="/wiki/Membrane_transport_protein" title="Membrane transport protein">Membrane transport protein</a>: <a href="/wiki/Ion_transporter" title="Ion transporter">ion pumps</a>, <a href="/wiki/ATPase" title="ATPase">ATPases</a> / <a href="/wiki/ATP_synthase" title="ATP synthase">ATP synthase</a> (<a href="/wiki/Transporter_Classification_database#3.A._P-P-bond_hydrolysis-driven_transporters" class="mw-redirect" title="Transporter Classification database">TC 3A2-3A3</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/ATP_synthase" title="ATP synthase">F-, V-, and A-type ATPase (3.A.2)</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/F-ATPase" title="F-ATPase">H<sup>+</sup> (F-type)</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>H<sup>+</sup> transporting, mitochondrial: <a href="/wiki/ATP5A1" class="mw-redirect" title="ATP5A1">ATP5A1</a></li> <li><a href="/wiki/ATP5B" title="ATP5B">ATP5B</a></li> <li><a href="/wiki/ATP5C1" title="ATP5C1">ATP5C1</a></li> <li><a href="/w/index.php?title=ATP5C2&action=edit&redlink=1" class="new" title="ATP5C2 (page does not exist)">ATP5C2</a></li> <li><a href="/wiki/ATP5D" title="ATP5D">ATP5D</a></li> <li><a href="/wiki/ATP5E" title="ATP5E">ATP5E</a></li> <li><a href="/wiki/ATP5F1" title="ATP5F1">ATP5F1</a></li> <li><a href="/wiki/ATP5G1" title="ATP5G1">ATP5G1</a></li> <li><a href="/wiki/ATP5G2" title="ATP5G2">ATP5G2</a></li> <li><a href="/wiki/ATP5G3" title="ATP5G3">ATP5G3</a></li> <li><a href="/wiki/ATP5H" title="ATP5H">ATP5H</a></li> <li><a href="/wiki/ATP5I" title="ATP5I">ATP5I</a></li> <li><a href="/wiki/ATP5J" class="mw-redirect" title="ATP5J">ATP5J</a></li> <li><a href="/wiki/ATP5J2" title="ATP5J2">ATP5J2</a></li> <li><a href="/wiki/ATP5L" title="ATP5L">ATP5L</a></li> <li><a href="/w/index.php?title=ATP5L2&action=edit&redlink=1" class="new" title="ATP5L2 (page does not exist)">ATP5L2</a></li> <li><a href="/wiki/ATP5O" class="mw-redirect" title="ATP5O">ATP5O</a></li> <li><a href="/wiki/ATP5S" title="ATP5S">ATP5S</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/V-ATPase" title="V-ATPase">H<sup>+</sup> (V-type)</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/V-ATPase" title="V-ATPase">H<sup>+</sup> transporting, lysosomal</a>: <a href="/wiki/ATP6AP1" title="ATP6AP1">ATP6AP1</a></li> <li><a href="/wiki/ATP6AP2" class="mw-redirect" title="ATP6AP2">ATP6AP2</a></li> <li><a href="/wiki/ATP6V1A" title="ATP6V1A">ATP6V1A</a></li> <li><a href="/wiki/ATP6V1B1" title="ATP6V1B1">ATP6V1B1</a></li> <li><a href="/wiki/ATP6V1B2" title="ATP6V1B2">ATP6V1B2</a></li> <li><a href="/wiki/ATP6V1C1" title="ATP6V1C1">ATP6V1C1</a></li> <li><a href="/wiki/ATP6V1C2" title="ATP6V1C2">ATP6V1C2</a></li> <li><a href="/wiki/ATP6V1D" title="ATP6V1D">ATP6V1D</a></li> <li><a href="/wiki/ATP6V1E1" title="ATP6V1E1">ATP6V1E1</a></li> <li><a href="/wiki/ATP6V1E2" title="ATP6V1E2">ATP6V1E2</a></li> <li><a href="/wiki/ATP6V1F" title="ATP6V1F">ATP6V1F</a></li> <li><a href="/wiki/ATP6V1G1" title="ATP6V1G1">ATP6V1G1</a></li> <li><a href="/wiki/ATP6V1G2" title="ATP6V1G2">ATP6V1G2</a></li> <li><a href="/wiki/ATP6V1G3" title="ATP6V1G3">ATP6V1G3</a></li> <li><a href="/wiki/ATP6V1H" title="ATP6V1H">ATP6V1H</a></li> <li><a href="/wiki/ATP6V0A1" class="mw-redirect" title="ATP6V0A1">ATP6V0A1</a></li> <li><a href="/wiki/ATP6V0A2" title="ATP6V0A2">ATP6V0A2</a></li> <li><a href="/wiki/ATP6V0A4" title="ATP6V0A4">ATP6V0A4</a></li> <li><a href="/wiki/ATP6V0B" title="ATP6V0B">ATP6V0B</a></li> <li><a href="/wiki/ATP6V0C" title="ATP6V0C">ATP6V0C</a></li> <li><a href="/wiki/ATP6V0D1" title="ATP6V0D1">ATP6V0D1</a></li> <li><a href="/wiki/ATP6V0D2" title="ATP6V0D2">ATP6V0D2</a></li> <li><a href="/w/index.php?title=ATP6V0E&action=edit&redlink=1" class="new" title="ATP6V0E (page does not exist)">ATP6V0E</a></li> <li><a href="/wiki/ATP6V0E1" title="ATP6V0E1">ATP6V0E1</a></li></ul> <ul><li><a href="/wiki/TCIRG1" title="TCIRG1">TCIRG1</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/ATPase#Classification" title="ATPase">A-ATPase</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em">found in Archea</div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/P-type_ATPase" title="P-type ATPase">P-type ATPase</a> (3.A.3)</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>3.A.3.1.1: <a href="/wiki/Na%2B/K%2B-ATPase" class="mw-redirect" title="Na+/K+-ATPase">Na<sup>+</sup>/K<sup>+</sup> transporting</a>: <a href="/wiki/ATP1A1" class="mw-redirect" title="ATP1A1">ATP1A1</a></li> <li><a href="/wiki/ATP1A2" title="ATP1A2">ATP1A2</a></li> <li><a href="/wiki/ATP1A3" title="ATP1A3">ATP1A3</a></li> <li><a href="/wiki/ATP1A4" title="ATP1A4">ATP1A4</a></li> <li><a href="/wiki/ATP1B1" title="ATP1B1">ATP1B1</a></li> <li><a href="/w/index.php?title=ATP1B2&action=edit&redlink=1" class="new" title="ATP1B2 (page does not exist)">ATP1B2</a></li> <li><a href="/wiki/ATP1B3" title="ATP1B3">ATP1B3</a></li> <li><a href="/w/index.php?title=ATP1B4&action=edit&redlink=1" class="new" title="ATP1B4 (page does not exist)">ATP1B4</a></li> <li><a href="/w/index.php?title=ATP1G1&action=edit&redlink=1" class="new" title="ATP1G1 (page does not exist)">ATP1G1</a></li></ul> <ul><li>3.A.3.1.2: <a href="/wiki/Hydrogen_potassium_ATPase" title="Hydrogen potassium ATPase">H<sup>+</sup>/K<sup>+</sup></a></li> <li><a href="/wiki/Hydrogen_potassium_ATPase" title="Hydrogen potassium ATPase">H<sup>+</sup>/K<sup>+</sup> exchanging</a>: <a href="/w/index.php?title=ATP4A&action=edit&redlink=1" class="new" title="ATP4A (page does not exist)">ATP4A</a></li> <li><a href="/w/index.php?title=ATP4B&action=edit&redlink=1" class="new" title="ATP4B (page does not exist)">ATP4B</a></li></ul> <ul><li>3.A.3.1.4: H<sup>+</sup>/K<sup>+</sup> transporting, nongastric: <a href="/wiki/ATP12A" title="ATP12A">ATP12A</a></li></ul> <ul><li>3.A.3.2: <a href="/wiki/Calcium_ATPase" title="Calcium ATPase">Ca<sup>2+</sup></a> (<a href="/wiki/SERCA" title="SERCA">SERCA</a>, <a href="/wiki/Plasma_membrane_Ca%C2%B2%E2%81%BA_ATPase" class="mw-redirect" title="Plasma membrane Ca²⁺ ATPase">PMCA</a>, <a href="/wiki/Secretory_Pathway_Ca%C2%B2%E2%81%BA_ATPase" title="Secretory Pathway Ca²⁺ ATPase">SPCA</a>) / <a href="/wiki/Calcium_ATPase" title="Calcium ATPase">Ca<sup>2+</sup> transporting</a>: <a href="/wiki/ATP2A1" title="ATP2A1">ATP2A1</a></li> <li><a href="/wiki/ATP2A2" title="ATP2A2">ATP2A2</a></li> <li><a href="/wiki/ATP2A3" title="ATP2A3">ATP2A3</a></li> <li><a href="/wiki/ATP2B1" title="ATP2B1">ATP2B1</a></li> <li><a href="/wiki/ATP2B2" title="ATP2B2">ATP2B2</a></li> <li><a href="/wiki/ATP2B3" title="ATP2B3">ATP2B3</a></li> <li><a href="/wiki/ATP2B4" title="ATP2B4">ATP2B4</a></li> <li><a href="/wiki/ATP2C1" title="ATP2C1">ATP2C1</a></li></ul> <ul><li>3.A.3.5: Cu<sup>2+</sup> transporting: <a href="/wiki/ATP7A" title="ATP7A">ATP7A</a></li> <li><a href="/wiki/Wilson_disease_protein" title="Wilson disease protein">ATP7B</a></li></ul> <ul><li>3.A.3.8.8: <a href="/wiki/Flippase" title="Flippase">flippase</a>: <a href="/w/index.php?title=ATP8A2&action=edit&redlink=1" class="new" title="ATP8A2 (page does not exist)">ATP8A2</a></li></ul> <ul><li>Other/ungrouped:</li></ul> <ul><li><a href="/wiki/Na%2B/K%2B-ATPase" class="mw-redirect" title="Na+/K+-ATPase">Na<sup>+</sup>/K<sup>+</sup></a> – <a href="/wiki/Proton_ATPase" title="Proton ATPase">H<sup>+</sup></a></li></ul> <ul><li><a href="/wiki/Mg%2B%2B_transporting" class="mw-redirect" title="Mg++ transporting">Mg<sup>2+</sup> transporting</a>: <a href="/wiki/ATP3" class="mw-redirect" title="ATP3">ATP3</a></li> <li>Class I, type 8: <a href="/w/index.php?title=ATP8A1&action=edit&redlink=1" class="new" title="ATP8A1 (page does not exist)">ATP8A1</a></li> <li><a href="/wiki/ATP8B1" class="mw-redirect" title="ATP8B1">ATP8B1</a></li> <li><a href="/w/index.php?title=ATP8B2&action=edit&redlink=1" class="new" title="ATP8B2 (page does not exist)">ATP8B2</a></li> <li><a href="/wiki/ATP8B3" title="ATP8B3">ATP8B3</a></li> <li><a href="/w/index.php?title=ATP8B4&action=edit&redlink=1" class="new" title="ATP8B4 (page does not exist)">ATP8B4</a></li> <li>Class II, type 9: <a href="/wiki/ATP9A" title="ATP9A">ATP9A</a></li> <li><a href="/w/index.php?title=ATP9B&action=edit&redlink=1" class="new" title="ATP9B (page does not exist)">ATP9B</a></li> <li>Class V, type 10: <a href="/wiki/ATP10A" class="mw-redirect" title="ATP10A">ATP10A</a></li> <li><a href="/w/index.php?title=ATP10B&action=edit&redlink=1" class="new" title="ATP10B (page does not exist)">ATP10B</a></li> <li><a href="/w/index.php?title=ATP10D&action=edit&redlink=1" class="new" title="ATP10D (page does not exist)">ATP10D</a></li> <li>Class VI, type 11: <a href="/w/index.php?title=ATP11A&action=edit&redlink=1" class="new" title="ATP11A (page does not exist)">ATP11A</a></li> <li><a href="/wiki/ATP11B" title="ATP11B">ATP11B</a></li> <li><a href="/wiki/ATP11C" title="ATP11C">ATP11C</a></li> <li>type 13: <a href="/w/index.php?title=ATP13A1&action=edit&redlink=1" class="new" title="ATP13A1 (page does not exist)">ATP13A1</a></li> <li><a href="/wiki/ATP13A2" title="ATP13A2">ATP13A2</a></li> <li><a href="/wiki/ATP13A3" title="ATP13A3">ATP13A3</a></li> <li><a href="/w/index.php?title=ATP13A4&action=edit&redlink=1" class="new" title="ATP13A4 (page does not exist)">ATP13A4</a></li> <li><a href="/w/index.php?title=ATP13A5&action=edit&redlink=1" class="new" title="ATP13A5 (page does not exist)">ATP13A5</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background-color: AntiqueWhite"><div><i>see also <a href="/wiki/Template:ATPase_disorders" title="Template:ATPase disorders">ATPase disorders</a></i></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Membrane_proteins,_carrier_proteins:_membrane_transport_proteins_solute_carrier_(TC_2A)" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e7dcc3"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Solute_carrier_family" title="Template:Solute carrier family"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Solute_carrier_family" title="Template talk:Solute carrier family"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Solute_carrier_family" title="Special:EditPage/Template:Solute carrier family"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Membrane_proteins,_carrier_proteins:_membrane_transport_proteins_solute_carrier_(TC_2A)" style="font-size:114%;margin:0 4em"><a href="/wiki/Membrane_protein" title="Membrane protein">Membrane proteins</a>, <a href="/wiki/Carrier_protein" class="mw-redirect" title="Carrier protein">carrier proteins</a>: <a href="/wiki/Membrane_transport_protein" title="Membrane transport protein">membrane transport proteins</a> <a href="/wiki/Solute_carrier_family" title="Solute carrier family">solute carrier</a> (<a href="/wiki/Transporter_Classification_Database#2.A.09Porters_(uniporters,_symporters,_antiporters)" title="Transporter Classification Database">TC 2A</a>)</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background-color: AntiqueWhite;"><div id="By_group" style="font-size:114%;margin:0 4em">By group</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="text-align:left; background-color: AntiqueWhite;"><div id="SLC1–10" style="font-size:114%;margin:0 4em">SLC1–10</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0;text-align:left;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(1):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Excitatory_amino-acid_transporter" class="mw-redirect" title="Excitatory amino-acid transporter">high affinity glutamate and neutral amino-acid transporter</a> <ul><li><a href="/wiki/SLC1A1" class="mw-redirect" title="SLC1A1">SLC1A1</a></li> <li><a href="/wiki/SLC1A2" class="mw-redirect" title="SLC1A2">2</a></li> <li><a href="/wiki/Glutamate_aspartate_transporter" class="mw-redirect" title="Glutamate aspartate transporter">3</a></li> <li><a href="/wiki/SLC1A4" class="mw-redirect" title="SLC1A4">4</a></li> <li><a href="/wiki/SLC1A5" class="mw-redirect" title="SLC1A5">5</a></li> <li><a href="/wiki/Excitatory_amino-acid_transporter_4" class="mw-redirect" title="Excitatory amino-acid transporter 4">6</a></li> <li><a href="/wiki/Excitatory_amino-acid_transporter_5" class="mw-redirect" title="Excitatory amino-acid transporter 5">7</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(2):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Glucose_transporter" title="Glucose transporter">facilitative GLUT transporter</a> <ul><li><a href="/wiki/GLUT1" title="GLUT1">SLC2A1</a></li> <li><a href="/wiki/GLUT2" title="GLUT2">2</a></li> <li><a href="/wiki/GLUT3" title="GLUT3">3</a></li> <li><a href="/wiki/GLUT4" title="GLUT4">4</a></li> <li><a href="/wiki/GLUT5" title="GLUT5">5</a></li> <li><a href="/wiki/SLC2A6" title="SLC2A6">6</a></li> <li><a href="/wiki/SLC2A7" title="SLC2A7">7</a></li> <li><a href="/wiki/GLUT8" title="GLUT8">8</a></li> <li><a href="/wiki/SLC2A9" title="SLC2A9">9</a></li> <li><a href="/wiki/SLC2A10" title="SLC2A10">10</a></li> <li><a href="/wiki/SLC2A11" title="SLC2A11">11</a></li> <li><a href="/wiki/SLC2A12" title="SLC2A12">12</a></li> <li><a href="/wiki/SLC2A13" title="SLC2A13">13</a></li> <li><a href="/wiki/SLC2A14" title="SLC2A14">14</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(3):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>heavy subunits of <a href="/wiki/Heterodimeric_amino-acid_transporter" title="Heterodimeric amino-acid transporter">heterodimeric amino-acid transporters</a> <ul><li><a href="/wiki/SLC3A1" class="mw-redirect" title="SLC3A1">SLC3A1</a></li> <li><a href="/wiki/SLC3A2" class="mw-redirect" title="SLC3A2">2</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(4):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Bicarbonate_transporter_protein" class="mw-redirect" title="Bicarbonate transporter protein">bicarbonate transporter</a> <ul><li><a href="/wiki/Band_3" class="mw-redirect" title="Band 3">SLC4A1</a></li> <li><a href="/wiki/SLC4A2" class="mw-redirect" title="SLC4A2">2</a></li> <li><a href="/wiki/SLC4A3" class="mw-redirect" title="SLC4A3">3</a></li> <li><a href="/wiki/SLC4A4" class="mw-redirect" title="SLC4A4">4</a></li> <li><a href="/wiki/SLC4A5" class="mw-redirect" title="SLC4A5">5</a></li> <li><a href="/wiki/SLC4A6" class="mw-redirect" title="SLC4A6">6</a></li> <li><a href="/wiki/SLC4A7" class="mw-redirect" title="SLC4A7">7</a></li> <li><a href="/wiki/SLC4A8" class="mw-redirect" title="SLC4A8">8</a></li> <li><a href="/w/index.php?title=SLC4A9&action=edit&redlink=1" class="new" title="SLC4A9 (page does not exist)">9</a></li> <li><a href="/w/index.php?title=SLC4A10&action=edit&redlink=1" class="new" title="SLC4A10 (page does not exist)">10</a></li> <li><a href="/wiki/SLC4A11" class="mw-redirect" title="SLC4A11">11</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(5):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Sodium-glucose_transport_proteins" title="Sodium-glucose transport proteins">sodium glucose cotransporter</a> <ul><li><a href="/wiki/SLC5A1" class="mw-redirect" title="SLC5A1">SLC5A1</a></li> <li><a href="/wiki/SGLT2" class="mw-redirect" title="SGLT2">2</a></li> <li><a href="/wiki/SLC5A3" class="mw-redirect" title="SLC5A3">3</a></li> <li><a href="/wiki/SLC5A4" title="SLC5A4">4</a></li> <li><a href="/wiki/Sodium-iodide_symporter" class="mw-redirect" title="Sodium-iodide symporter">5</a></li> <li><a href="/wiki/SLC5A6" class="mw-redirect" title="SLC5A6">6</a></li> <li><a href="/wiki/Choline_transporter" title="Choline transporter">7</a></li> <li><a href="/wiki/SLC5A8" class="mw-redirect" title="SLC5A8">8</a></li> <li><a href="/w/index.php?title=SLC5A9&action=edit&redlink=1" class="new" title="SLC5A9 (page does not exist)">9</a></li> <li><a href="/w/index.php?title=SLC5A10&action=edit&redlink=1" class="new" title="SLC5A10 (page does not exist)">10</a></li> <li><a href="/w/index.php?title=SLC5A11&action=edit&redlink=1" class="new" title="SLC5A11 (page does not exist)">11</a></li> <li><a href="/w/index.php?title=SLC5A12&action=edit&redlink=1" class="new" title="SLC5A12 (page does not exist)">12</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(6):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Sodium" title="Sodium">sodium</a>- and <a href="/wiki/Chloride" title="Chloride">chloride</a>- dependent <a href="/wiki/Sodium:neurotransmitter_symporter" class="mw-redirect" title="Sodium:neurotransmitter symporter">sodium:neurotransmitter symporters</a> <ul><li><a href="/wiki/GABA_transporter_1" class="mw-redirect" title="GABA transporter 1">SLC6A1</a></li> <li><a href="/wiki/Norepinephrine_transporter" title="Norepinephrine transporter">SLC6A2</a></li> <li><a href="/wiki/Dopamine_transporter" title="Dopamine transporter">SLC6A3</a></li> <li><a href="/wiki/Serotonin_transporter" title="Serotonin transporter">SLC6A4</a></li> <li><a href="/wiki/SLC6A5" class="mw-redirect" title="SLC6A5">SLC6A5</a></li> <li><a href="/wiki/SLC6A6" class="mw-redirect" title="SLC6A6">SLC6A6</a></li> <li><a href="/w/index.php?title=SLC6A7&action=edit&redlink=1" class="new" title="SLC6A7 (page does not exist)">SLC6A7</a></li> <li><a href="/wiki/SLC6A8" class="mw-redirect" title="SLC6A8">SLC6A8</a></li> <li><a href="/wiki/SLC6A9" class="mw-redirect" title="SLC6A9">SLC6A9</a></li> <li><a href="/w/index.php?title=SLC6A10&action=edit&redlink=1" class="new" title="SLC6A10 (page does not exist)">SLC6A10</a></li> <li><a href="/wiki/SLC6A11" class="mw-redirect" title="SLC6A11">SLC6A11</a></li> <li><a href="/wiki/SLC6A12" class="mw-redirect" title="SLC6A12">SLC6A12</a></li> <li><a href="/wiki/SLC6A13" class="mw-redirect" title="SLC6A13">SLC6A13</a></li> <li><a href="/wiki/SLC6A14" title="SLC6A14">SLC6A14</a></li> <li><a href="/wiki/SLC6A15" class="mw-redirect" title="SLC6A15">SLC6A15</a></li> <li><a href="/w/index.php?title=SLC6A16&action=edit&redlink=1" class="new" title="SLC6A16 (page does not exist)">SLC6A16</a></li> <li><a href="/w/index.php?title=SLC6A17&action=edit&redlink=1" class="new" title="SLC6A17 (page does not exist)">SLC6A17</a></li> <li><a href="/wiki/SLC6A18" title="SLC6A18">SLC6A18</a></li> <li><a href="/wiki/SLC6A19" class="mw-redirect" title="SLC6A19">SLC6A19</a></li> <li><a href="/wiki/SLC6A20" title="SLC6A20">SLC6A20</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(7):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>cationic amino-acid transporter/glycoprotein-associated <ul><li><a href="/wiki/SLC7A1" class="mw-redirect" title="SLC7A1">SLC7A1</a></li> <li><a href="/wiki/SLC7A2" class="mw-redirect" title="SLC7A2">SLC7A2</a></li> <li><a href="/wiki/SLC7A3" class="mw-redirect" title="SLC7A3">SLC7A3</a></li> <li><a href="/wiki/SLC7A4" class="mw-redirect" title="SLC7A4">SLC7A4</a></li></ul></li> <li>glycoprotein-associated/light or catalytic subunits of <a href="/wiki/Heterodimeric_amino-acid_transporter" title="Heterodimeric amino-acid transporter">heterodimeric amino-acid transporters</a> <ul><li><a href="/wiki/CD98" title="CD98">SLC7A5</a></li> <li><a href="/wiki/SLC7A6" class="mw-redirect" title="SLC7A6">SLC7A6</a></li> <li><a href="/wiki/SLC7A7" class="mw-redirect" title="SLC7A7">SLC7A7</a></li> <li><a href="/wiki/SLC7A8" class="mw-redirect" title="SLC7A8">SLC7A8</a></li> <li><a href="/wiki/SLC7A9" class="mw-redirect" title="SLC7A9">SLC7A9</a></li> <li><a href="/wiki/SLC7A10" class="mw-redirect" title="SLC7A10">SLC7A10</a></li> <li><a href="/wiki/SLC7A11" class="mw-redirect" title="SLC7A11">SLC7A11</a></li> <li><a href="/w/index.php?title=SLC7A13&action=edit&redlink=1" class="new" title="SLC7A13 (page does not exist)">SLC7A13</a></li> <li><a href="/wiki/SLC7A14" title="SLC7A14">SLC7A14</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(8):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Sodium-calcium_exchanger" title="Sodium-calcium exchanger">Na<sup>+</sup>/Ca<sup>2+</sup> exchanger</a> <ul><li><a href="/wiki/SLC8A1" class="mw-redirect" title="SLC8A1">SLC8A1</a></li> <li><a href="/w/index.php?title=SLC8A2&action=edit&redlink=1" class="new" title="SLC8A2 (page does not exist)">SLC8A2</a></li> <li><a href="/w/index.php?title=SLC8A3&action=edit&redlink=1" class="new" title="SLC8A3 (page does not exist)">SLC8A3</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(9):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Sodium%E2%80%93hydrogen_antiporter" title="Sodium–hydrogen antiporter">Na<sup>+</sup>/H<sup>+</sup> exchanger</a> <ul><li><a href="/wiki/SLC9A1" class="mw-redirect" title="SLC9A1">SLC9A1</a></li> <li><a href="/wiki/SLC9A2" class="mw-redirect" title="SLC9A2">SLC9A2</a></li> <li><a href="/wiki/SLC9A3" class="mw-redirect" title="SLC9A3">SLC9A3</a></li> <li><a href="/w/index.php?title=SLC9A4&action=edit&redlink=1" class="new" title="SLC9A4 (page does not exist)">SLC9A4</a></li> <li><a href="/wiki/SLC9A5" class="mw-redirect" title="SLC9A5">SLC9A5</a></li> <li><a href="/wiki/SLC9A6" class="mw-redirect" title="SLC9A6">SLC9A6</a></li> <li><a href="/w/index.php?title=SLC9A7&action=edit&redlink=1" class="new" title="SLC9A7 (page does not exist)">SLC9A7</a></li> <li><a href="/wiki/SLC9A8" class="mw-redirect" title="SLC9A8">SLC9A8</a></li> <li><a href="/w/index.php?title=SLC9A9&action=edit&redlink=1" class="new" title="SLC9A9 (page does not exist)">SLC9A9</a></li> <li><a href="/wiki/SLC9A10" class="mw-redirect" title="SLC9A10">SLC9A10</a></li> <li><a href="/wiki/SLC9A11" class="mw-redirect" title="SLC9A11">SLC9A11</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(10):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Sodium_bile_salt_cotransport&action=edit&redlink=1" class="new" title="Sodium bile salt cotransport (page does not exist)">sodium bile salt cotransport</a> <ul><li><a href="/wiki/SLC10A1" class="mw-redirect" title="SLC10A1">SLC10A1</a></li> <li><a href="/wiki/SLC10A2" class="mw-redirect" title="SLC10A2">SLC10A2</a></li> <li><a href="/wiki/SLC10A3" class="mw-redirect" title="SLC10A3">SLC10A3</a></li> <li><a href="/w/index.php?title=SLC10A4&action=edit&redlink=1" class="new" title="SLC10A4 (page does not exist)">SLC10A4</a></li> <li><a href="/w/index.php?title=SLC10A5&action=edit&redlink=1" class="new" title="SLC10A5 (page does not exist)">SLC10A5</a></li> <li><a href="/w/index.php?title=SLC10A6&action=edit&redlink=1" class="new" title="SLC10A6 (page does not exist)">SLC10A6</a></li> <li><a href="/wiki/SLC10A7" class="mw-redirect" title="SLC10A7">SLC10A7</a></li></ul></li> <li><a href="/wiki/SLC10A1" class="mw-redirect" title="SLC10A1">10A1</a></li> <li><a href="/wiki/SLC10A2" class="mw-redirect" title="SLC10A2">10A2</a></li> <li><a href="/wiki/SLC10A3" class="mw-redirect" title="SLC10A3">10A3</a></li> <li><a href="/wiki/SLC10A7" class="mw-redirect" title="SLC10A7">10A7</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="text-align:left; background-color: AntiqueWhite;"><div id="SLC11–20" style="font-size:114%;margin:0 4em">SLC11–20</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0;text-align:left;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(11):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Proton_coupled_metal_ion_transporter&action=edit&redlink=1" class="new" title="Proton coupled metal ion transporter (page does not exist)">proton coupled metal ion transporter</a> <ul><li><a href="/wiki/SLC11A1" class="mw-redirect" title="SLC11A1">SLC11A1</a></li> <li><a href="/wiki/SLC11A2" class="mw-redirect" title="SLC11A2">SLC11A2</a><a href="/wiki/Ferroportin" title="Ferroportin">11A3</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(12):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Electroneutral_cation-Cl" title="Electroneutral cation-Cl">electroneutral cation-Cl</a> cotransporter <ul><li><a href="/wiki/Na-K-Cl_cotransporter" class="mw-redirect" title="Na-K-Cl cotransporter">SLC12A1</a></li> <li><a href="/wiki/Na-K-Cl_cotransporter" class="mw-redirect" title="Na-K-Cl cotransporter">SLC12A2</a></li> <li><a href="/wiki/Sodium-chloride_symporter" title="Sodium-chloride symporter">SLC12A3</a></li> <li><a href="/wiki/Chloride_potassium_symporter_4" title="Chloride potassium symporter 4">SLC12A4</a></li> <li><a href="/wiki/Chloride_potassium_symporter_5" title="Chloride potassium symporter 5">SLC12A5</a></li> <li><a href="/wiki/SLC12A6" title="SLC12A6">SLC12A6</a></li> <li><a href="/wiki/SLC12A7" title="SLC12A7">SLC12A7</a></li> <li><a href="/wiki/SLC12A8" title="SLC12A8">SLC12A8</a></li> <li><a href="/wiki/SLC12A9" title="SLC12A9">SLC12A9</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(13):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Human_Na%2B-sulfate/carboxylate_cotransporter&action=edit&redlink=1" class="new" title="Human Na+-sulfate/carboxylate cotransporter (page does not exist)">human Na<sup>+</sup>-sulfate/carboxylate cotransporter</a> <ul><li><a href="/w/index.php?title=SLC13A1&action=edit&redlink=1" class="new" title="SLC13A1 (page does not exist)">SLC13A1</a></li> <li><a href="/wiki/SLC13A2" title="SLC13A2">SLC13A2</a></li> <li><a href="/wiki/SLC13A3" title="SLC13A3">SLC13A3</a></li> <li><a href="/w/index.php?title=SLC13A4&action=edit&redlink=1" class="new" title="SLC13A4 (page does not exist)">SLC13A4</a></li> <li><a href="/wiki/SLC13A5" title="SLC13A5">SLC13A5</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(14):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Urea_transporter" title="Urea transporter">urea transporter</a> <ul><li><a href="/wiki/SLC14A1" class="mw-redirect" title="SLC14A1">SLC14A1</a></li> <li><a href="/wiki/SLC14A2" class="mw-redirect" title="SLC14A2">SLC14A2</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(15):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Proton_oligopeptide_cotransporter&action=edit&redlink=1" class="new" title="Proton oligopeptide cotransporter (page does not exist)">proton oligopeptide cotransporter</a> <ul><li><a href="/wiki/Peptide_transporter_1" title="Peptide transporter 1">SLC15A1</a></li> <li><a href="/wiki/SLC15A2" title="SLC15A2">SLC15A2</a></li> <li><a href="/w/index.php?title=SLC15A3&action=edit&redlink=1" class="new" title="SLC15A3 (page does not exist)">SLC15A3</a></li> <li><a href="/wiki/SLC15A4" title="SLC15A4">SLC15A4</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(16):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Monocarboxylate&action=edit&redlink=1" class="new" title="Monocarboxylate (page does not exist)">monocarboxylate</a> transporter <ul><li><a href="/wiki/Monocarboxylate_transporter_1" title="Monocarboxylate transporter 1">SLC16A1</a></li> <li><a href="/wiki/Monocarboxylate_transporter_8" title="Monocarboxylate transporter 8">SLC16A2</a></li> <li><a href="/wiki/Monocarboxylate_transporter_4" title="Monocarboxylate transporter 4">SLC16A3</a></li> <li><a href="/wiki/Monocarboxylate_transporter_5" title="Monocarboxylate transporter 5">SLC16A4</a></li> <li><a href="/wiki/SLC16A5" class="mw-redirect" title="SLC16A5">SLC16A5</a></li> <li><a href="/w/index.php?title=SLC16A6&action=edit&redlink=1" class="new" title="SLC16A6 (page does not exist)">SLC16A6</a></li> <li><a href="/wiki/Monocarboxylate_transporter_2" title="Monocarboxylate transporter 2">SLC16A7</a></li> <li><a href="/wiki/Monocarboxylate_transporter_3" title="Monocarboxylate transporter 3">SLC16A8</a></li> <li><a href="/wiki/Monocarboxylate_transporter_9" title="Monocarboxylate transporter 9">SLC16A9</a></li> <li><a href="/wiki/Monocarboxylate_transporter_10" title="Monocarboxylate transporter 10">SLC16A10</a></li> <li><a href="/wiki/SLC16A11" title="SLC16A11">SLC16A11</a></li> <li><a href="/w/index.php?title=SLC16A12&action=edit&redlink=1" class="new" title="SLC16A12 (page does not exist)">SLC16A12</a></li> <li><a href="/w/index.php?title=SLC16A13&action=edit&redlink=1" class="new" title="SLC16A13 (page does not exist)">SLC16A13</a></li> <li><a href="/w/index.php?title=SLC16A14&action=edit&redlink=1" class="new" title="SLC16A14 (page does not exist)">SLC16A14</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(17):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Vesicular_glutamate_transporter_1" title="Vesicular glutamate transporter 1">Vesicular glutamate transporter 1</a> <ul><li><a href="/wiki/SLC17A1" class="mw-redirect" title="SLC17A1">SLC17A1</a></li> <li><a href="/w/index.php?title=SLC17A2&action=edit&redlink=1" class="new" title="SLC17A2 (page does not exist)">SLC17A2</a></li> <li><a href="/wiki/SLC17A3" title="SLC17A3">SLC17A3</a></li> <li><a href="/w/index.php?title=SLC17A4&action=edit&redlink=1" class="new" title="SLC17A4 (page does not exist)">SLC17A4</a></li> <li><a href="/wiki/SLC17A5" class="mw-redirect" title="SLC17A5">SLC17A5</a></li> <li><a href="/w/index.php?title=SLC17A6&action=edit&redlink=1" class="new" title="SLC17A6 (page does not exist)">SLC17A6</a></li> <li><a href="/wiki/SLC17A7" class="mw-redirect" title="SLC17A7">SLC17A7</a></li> <li><a href="/wiki/SLC17A8" class="mw-redirect" title="SLC17A8">SLC17A8</a></li> <li><a href="/wiki/SLC17A9" title="SLC17A9">SLC17A9</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(18):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Vesicular_monoamine_transporter" title="Vesicular monoamine transporter">vesicular monoamine transporter</a> <ul><li><a href="/wiki/VMAT1" class="mw-redirect" title="VMAT1">SLC18A1</a></li> <li><a href="/wiki/VMAT2" class="mw-redirect" title="VMAT2">SLC18A2</a></li> <li><a href="/wiki/Vesicular_acetylcholine_transporter" title="Vesicular acetylcholine transporter">SLC18A3</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(19):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Folate" title="Folate">folate</a>/<a href="/wiki/Thiamine" title="Thiamine">thiamine</a> transporter <ul><li><a href="/wiki/SLC19A1" class="mw-redirect" title="SLC19A1">SLC19A1</a></li> <li><a href="/wiki/SLC19A2" class="mw-redirect" title="SLC19A2">SLC19A2</a></li> <li><a href="/wiki/SLC19A3" class="mw-redirect" title="SLC19A3">SLC19A3</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(20):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Type_III_Na%2B-phosphate" class="mw-redirect" title="Type III Na+-phosphate">type III Na<sup>+</sup>-phosphate</a> cotransporter <ul><li><a href="/wiki/SLC20A1" title="SLC20A1">SLC20A1</a></li> <li><a href="/wiki/SLC20A2" title="SLC20A2">SLC20A2</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="text-align:left; background-color: AntiqueWhite;"><div id="SLC21–30" style="font-size:114%;margin:0 4em">SLC21–30</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0;text-align:left;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(21):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Organic_anion-transporting_polypeptide" class="mw-redirect" title="Organic anion-transporting polypeptide">Organic anion-transporting polypeptide</a> <ul><li><a href="/wiki/SLCO1A2" class="mw-redirect" title="SLCO1A2">SLCO1A2</a></li> <li><a href="/wiki/SLCO1B1" class="mw-redirect" title="SLCO1B1">SLCO1B1</a></li> <li><a href="/wiki/SLCO1B3" class="mw-redirect" title="SLCO1B3">SLCO1B3</a></li> <li><a href="/w/index.php?title=SLCO1B4&action=edit&redlink=1" class="new" title="SLCO1B4 (page does not exist)">SLCO1B4</a></li> <li><a href="/wiki/SLCO1C1" class="mw-redirect" title="SLCO1C1">SLCO1C1</a></li></ul></li> <li> <ul><li><a href="/wiki/SLCO2A1" class="mw-redirect" title="SLCO2A1">SLCO2A1</a></li> <li><a href="/wiki/SLCO2B1" class="mw-redirect" title="SLCO2B1">SLCO2B1</a></li></ul></li> <li> <ul><li><a href="/wiki/SLCO3A1" class="mw-redirect" title="SLCO3A1">SLCO3A1</a></li></ul></li> <li> <ul><li><a href="/wiki/SLCO4A1" class="mw-redirect" title="SLCO4A1">SLCO4A1</a></li> <li><a href="/w/index.php?title=SLCO4C1&action=edit&redlink=1" class="new" title="SLCO4C1 (page does not exist)">SLCO4C1</a></li></ul></li> <li> <ul><li><a href="/w/index.php?title=SLCO5A1&action=edit&redlink=1" class="new" title="SLCO5A1 (page does not exist)">SLCO5A1</a>(<a href="/w/index.php?title=SLCO6A1&action=edit&redlink=1" class="new" title="SLCO6A1 (page does not exist)">SLCO6A1</a>)</li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(22):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Organic_cation/anion/zwitterion_transporter" class="mw-redirect" title="Organic cation/anion/zwitterion transporter">organic cation/anion/zwitterion transporter</a> <ul><li><a href="/wiki/SLC22A1" title="SLC22A1">SLC22A1</a></li> <li><a href="/wiki/SLC22A2" title="SLC22A2">SLC22A2</a></li> <li><a href="/wiki/SLC22A3" title="SLC22A3">SLC22A3</a></li> <li><a href="/wiki/SLC22A4" title="SLC22A4">SLC22A4</a></li> <li><a href="/wiki/SLC22A5" title="SLC22A5">SLC22A5</a></li> <li><a href="/wiki/SLC22A6" class="mw-redirect" title="SLC22A6">SLC22A6</a></li> <li><a href="/wiki/SLC22A7" title="SLC22A7">SLC22A7</a></li> <li><a href="/wiki/SLC22A8" title="SLC22A8">SLC22A8</a></li> <li><a href="/wiki/SLC22A9" title="SLC22A9">SLC22A9</a></li> <li><a href="/wiki/SLC22A10" title="SLC22A10">SLC22A10</a></li> <li><a href="/wiki/SLC22A11" title="SLC22A11">SLC22A11</a></li> <li><a href="/wiki/SLC22A12" title="SLC22A12">SLC22A12</a></li> <li><a href="/wiki/SLC22A13" title="SLC22A13">SLC22A13</a></li> <li><a href="/wiki/SLC22A14" title="SLC22A14">SLC22A14</a></li> <li><a href="/wiki/SLC22A15" class="mw-redirect" title="SLC22A15">SLC22A15</a></li> <li><a href="/w/index.php?title=SLC22A16&action=edit&redlink=1" class="new" title="SLC22A16 (page does not exist)">SLC22A16</a></li> <li><a href="/w/index.php?title=SLC22A17&action=edit&redlink=1" class="new" title="SLC22A17 (page does not exist)">SLC22A17</a></li> <li><a href="/wiki/SLC22A18" title="SLC22A18">SLC22A18</a></li> <li><a href="/wiki/SLC22A19" class="mw-redirect" title="SLC22A19">SLC22A19</a></li> <li><a href="/w/index.php?title=SLC22A20&action=edit&redlink=1" class="new" title="SLC22A20 (page does not exist)">SLC22A20</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(23):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Na%2B-dependent_ascorbic_acid_transporter&action=edit&redlink=1" class="new" title="Na+-dependent ascorbic acid transporter (page does not exist)">Na+-dependent ascorbic acid transporter</a> <ul><li><a href="/wiki/SLC23A1" title="SLC23A1">SLC23A1</a></li> <li><a href="/wiki/SLC23A2" title="SLC23A2">SLC23A2</a></li> <li><a href="/w/index.php?title=SLC23A3&action=edit&redlink=1" class="new" title="SLC23A3 (page does not exist)">SLC23A3</a></li> <li><a href="/w/index.php?title=SLC23A4&action=edit&redlink=1" class="new" title="SLC23A4 (page does not exist)">SLC23A4</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(24):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Na%2B/(Ca2%2B-K%2B)_exchanger" class="mw-redirect" title="Na+/(Ca2+-K+) exchanger">Na<sup>+</sup>/(Ca<sup>2+</sup>-K<sup>+</sup>) exchanger</a> <ul><li><a href="/w/index.php?title=SLC24A1&action=edit&redlink=1" class="new" title="SLC24A1 (page does not exist)">SLC24A1</a></li> <li><a href="/w/index.php?title=SLC24A2&action=edit&redlink=1" class="new" title="SLC24A2 (page does not exist)">SLC24A2</a></li> <li><a href="/w/index.php?title=SLC24A3&action=edit&redlink=1" class="new" title="SLC24A3 (page does not exist)">SLC24A3</a></li> <li><a href="/wiki/SLC24A4" class="mw-redirect" title="SLC24A4">SLC24A4</a></li> <li><a href="/wiki/SLC24A5" class="mw-redirect" title="SLC24A5">SLC24A5</a></li> <li><a href="/w/index.php?title=SLC24A6&action=edit&redlink=1" class="new" title="SLC24A6 (page does not exist)">SLC24A6</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(25):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Mitochondrial_carrier" title="Mitochondrial carrier">mitochondrial carrier</a> <ul><li><a href="/wiki/SLC25A1" class="mw-redirect" title="SLC25A1">SLC25A1</a></li> <li><a href="/w/index.php?title=SLC25A2&action=edit&redlink=1" class="new" title="SLC25A2 (page does not exist)">SLC25A2</a></li> <li><a href="/wiki/SLC25A3" class="mw-redirect" title="SLC25A3">SLC25A3</a></li> <li><a href="/wiki/SLC25A4" class="mw-redirect" title="SLC25A4">SLC25A4</a></li> <li><a href="/wiki/SLC25A5" class="mw-redirect" title="SLC25A5">SLC25A5</a></li> <li><a href="/wiki/SLC25A6" class="mw-redirect" title="SLC25A6">SLC25A6</a></li> <li><a href="/wiki/Thermogenin" title="Thermogenin">SLC25A7</a></li> <li><a href="/wiki/SLC25A8" class="mw-redirect" title="SLC25A8">SLC25A8</a></li> <li><a href="/wiki/SLC25A9" class="mw-redirect" title="SLC25A9">SLC25A9</a></li> <li><a href="/wiki/SLC25A10" class="mw-redirect" title="SLC25A10">SLC25A10</a></li> <li><a href="/wiki/SLC25A11" class="mw-redirect" title="SLC25A11">SLC25A11</a></li> <li><a href="/wiki/SLC25A12" class="mw-redirect" title="SLC25A12">SLC25A12</a></li> <li><a href="/wiki/Citrin" title="Citrin">SLC25A13</a></li> <li><a href="/wiki/SLC25A14" class="mw-redirect" title="SLC25A14">SLC25A14</a></li> <li><a href="/wiki/Ornithine_translocase" title="Ornithine translocase">SLC25A15</a></li> <li><a href="/wiki/SLC25A16" title="SLC25A16">SLC25A16</a></li> <li><a href="/wiki/SLC25A17" class="mw-redirect" title="SLC25A17">SLC25A17</a></li> <li><a href="/w/index.php?title=SLC25A18&action=edit&redlink=1" class="new" title="SLC25A18 (page does not exist)">SLC25A18</a></li> <li><a href="/wiki/SLC25A19" class="mw-redirect" title="SLC25A19">SLC25A19</a></li> <li><a href="/wiki/Carnitine-acylcarnitine_translocase" title="Carnitine-acylcarnitine translocase">SLC25A20</a></li> <li><a href="/wiki/SLC25A21" class="mw-redirect" title="SLC25A21">SLC25A21</a></li> <li><a href="/wiki/SLC25A22" title="SLC25A22">SLC25A22</a></li> <li><a href="/w/index.php?title=SLC25A23&action=edit&redlink=1" class="new" title="SLC25A23 (page does not exist)">SLC25A23</a></li> <li><a href="/wiki/SLC25A24" class="mw-redirect" title="SLC25A24">SLC25A24</a></li> <li><a href="/w/index.php?title=SLC25A25&action=edit&redlink=1" class="new" title="SLC25A25 (page does not exist)">SLC25A25</a></li> <li><a href="/w/index.php?title=SLC25A26&action=edit&redlink=1" class="new" title="SLC25A26 (page does not exist)">SLC25A26</a></li> <li><a href="/wiki/SLC25A27" class="mw-redirect" title="SLC25A27">SLC25A27</a></li> <li><a href="/w/index.php?title=SLC25A28&action=edit&redlink=1" class="new" title="SLC25A28 (page does not exist)">SLC25A28</a></li> <li><a href="/wiki/SLC25A29" title="SLC25A29">SLC25A29</a></li> <li><a href="/w/index.php?title=SLC25A30&action=edit&redlink=1" class="new" title="SLC25A30 (page does not exist)">SLC25A30</a></li> <li><a href="/wiki/SLC25A31" class="mw-redirect" title="SLC25A31">SLC25A31</a></li> <li><a href="/wiki/SLC25A32" class="mw-redirect" title="SLC25A32">SLC25A32</a></li> <li><a href="/w/index.php?title=SLC25A33&action=edit&redlink=1" class="new" title="SLC25A33 (page does not exist)">SLC25A33</a></li> <li><a href="/w/index.php?title=SLC25A34&action=edit&redlink=1" class="new" title="SLC25A34 (page does not exist)">SLC25A34</a></li> <li><a href="/w/index.php?title=SLC25A35&action=edit&redlink=1" class="new" title="SLC25A35 (page does not exist)">SLC25A35</a></li> <li><a href="/w/index.php?title=SLC25A36&action=edit&redlink=1" class="new" title="SLC25A36 (page does not exist)">SLC25A36</a></li> <li><a href="/wiki/SLC25A37" class="mw-redirect" title="SLC25A37">SLC25A37</a></li> <li><a href="/wiki/SLC25A38" class="mw-redirect" title="SLC25A38">SLC25A38</a></li> <li><a href="/wiki/SLC25A39" title="SLC25A39">SLC25A39</a></li> <li><a href="/w/index.php?title=SLC25A40&action=edit&redlink=1" class="new" title="SLC25A40 (page does not exist)">SLC25A40</a></li> <li><a href="/w/index.php?title=SLC25A41&action=edit&redlink=1" class="new" title="SLC25A41 (page does not exist)">SLC25A41</a></li> <li><a href="/w/index.php?title=SLC25A42&action=edit&redlink=1" class="new" title="SLC25A42 (page does not exist)">SLC25A42</a></li> <li><a href="/w/index.php?title=SLC25A43&action=edit&redlink=1" class="new" title="SLC25A43 (page does not exist)">SLC25A43</a></li> <li><a href="/w/index.php?title=SLC25A44&action=edit&redlink=1" class="new" title="SLC25A44 (page does not exist)">SLC25A44</a></li> <li><a href="/w/index.php?title=SLC25A45&action=edit&redlink=1" class="new" title="SLC25A45 (page does not exist)">SLC25A45</a></li> <li><a href="/wiki/SLC25A46" title="SLC25A46">SLC25A46</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(26):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Multifunctional_anion_exchanger&action=edit&redlink=1" class="new" title="Multifunctional anion exchanger (page does not exist)">multifunctional anion exchanger</a> <ul><li><a href="/w/index.php?title=SLC26A1&action=edit&redlink=1" class="new" title="SLC26A1 (page does not exist)">SLC26A1</a></li> <li><a href="/wiki/SLC26A2" class="mw-redirect" title="SLC26A2">SLC26A2</a></li> <li><a href="/wiki/SLC26A3" class="mw-redirect" title="SLC26A3">SLC26A3</a></li> <li><a href="/wiki/Pendrin" title="Pendrin">SLC26A4</a></li> <li><a href="/wiki/SLC26A5" class="mw-redirect" title="SLC26A5">SLC26A5</a></li> <li><a href="/wiki/SLC26A6" title="SLC26A6">SLC26A6</a></li> <li><a href="/wiki/SLC26A7" class="mw-redirect" title="SLC26A7">SLC26A7</a></li> <li><a href="/wiki/SLC26A8" title="SLC26A8">SLC26A8</a></li> <li><a href="/w/index.php?title=SLC26A9&action=edit&redlink=1" class="new" title="SLC26A9 (page does not exist)">SLC26A9</a></li> <li><a href="/w/index.php?title=SLC26A10&action=edit&redlink=1" class="new" title="SLC26A10 (page does not exist)">SLC26A10</a></li> <li><a href="/w/index.php?title=SLC26A11&action=edit&redlink=1" class="new" title="SLC26A11 (page does not exist)">SLC26A11</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(27):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Membrane_transport_protein" title="Membrane transport protein">fatty acid transport proteins</a> <ul><li><a href="/wiki/SLC27A1" class="mw-redirect" title="SLC27A1">SLC27A1</a></li> <li><a href="/wiki/SLC27A2" class="mw-redirect" title="SLC27A2">SLC27A2</a></li> <li><a href="/wiki/SLC27A3" title="SLC27A3">SLC27A3</a></li> <li><a href="/wiki/SLC27A4" class="mw-redirect" title="SLC27A4">SLC27A4</a></li> <li><a href="/wiki/SLC27A5" title="SLC27A5">SLC27A5</a></li> <li><a href="/wiki/SLC27A6" title="SLC27A6">SLC27A6</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(28):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Na%2B-coupled_nucleoside_transport&action=edit&redlink=1" class="new" title="Na+-coupled nucleoside transport (page does not exist)">Na<sup>+</sup>-coupled nucleoside transport</a> (<a href="/wiki/SLC28A1" class="mw-redirect" title="SLC28A1">SLC28A1</a> <ul><li><a href="/wiki/SLC28A2" class="mw-redirect" title="SLC28A2">SLC28A2</a></li> <li><a href="/w/index.php?title=SLC28A3&action=edit&redlink=1" class="new" title="SLC28A3 (page does not exist)">SLC28A3</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(29):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Facilitative_nucleoside_transporter&action=edit&redlink=1" class="new" title="Facilitative nucleoside transporter (page does not exist)">facilitative nucleoside transporter</a> <ul><li><a href="/wiki/SLC29A1" class="mw-redirect" title="SLC29A1">SLC29A1</a></li> <li><a href="/wiki/SLC29A2" class="mw-redirect" title="SLC29A2">SLC29A2</a></li> <li><a href="/w/index.php?title=SLC29A3&action=edit&redlink=1" class="new" title="SLC29A3 (page does not exist)">SLC29A3</a></li> <li><a href="/wiki/SLC29A4" class="mw-redirect" title="SLC29A4">SLC29A4</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(30):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Zinc_efflux" class="mw-redirect" title="Zinc efflux">zinc efflux</a> <ul><li><a href="/wiki/SLC30A1" class="mw-redirect" title="SLC30A1">SLC30A1</a></li> <li><a href="/w/index.php?title=SLC30A2&action=edit&redlink=1" class="new" title="SLC30A2 (page does not exist)">SLC30A2</a></li> <li><a href="/wiki/SLC30A3" class="mw-redirect" title="SLC30A3">SLC30A3</a></li> <li><a href="/wiki/SLC30A4" class="mw-redirect" title="SLC30A4">SLC30A4</a></li> <li><a href="/w/index.php?title=SLC30A5&action=edit&redlink=1" class="new" title="SLC30A5 (page does not exist)">SLC30A5</a></li> <li><a href="/w/index.php?title=SLC30A6&action=edit&redlink=1" class="new" title="SLC30A6 (page does not exist)">SLC30A6</a></li> <li><a href="/wiki/SLC30A7" class="mw-redirect" title="SLC30A7">SLC30A7</a></li> <li><a href="/wiki/SLC30A8" class="mw-redirect" title="SLC30A8">SLC30A8</a></li> <li><a href="/w/index.php?title=SLC30A9&action=edit&redlink=1" class="new" title="SLC30A9 (page does not exist)">SLC30A9</a></li> <li><a href="/wiki/SLC30A10" class="mw-redirect" title="SLC30A10">SLC30A10</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="text-align:left; background-color: AntiqueWhite;"><div id="SLC31–40" style="font-size:114%;margin:0 4em">SLC31–40</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0;text-align:left;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(31):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Copper" title="Copper">copper</a> transporter <ul><li><a href="/wiki/SLC31A1" class="mw-redirect" title="SLC31A1">SLC31A1</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(32):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Vesicular_glutamate_transporter_1" title="Vesicular glutamate transporter 1">Vesicular glutamate transporter 1</a> <ul><li><a href="/wiki/SLC32A1" class="mw-redirect" title="SLC32A1">SLC32A1</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(33):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Acetyl-CoA" title="Acetyl-CoA">Acetyl-CoA</a> transporter <ul><li><a href="/wiki/SLC33A1" class="mw-redirect" title="SLC33A1">SLC33A1</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(34):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Type_II_Na%2B-phosphate_cotransporter&action=edit&redlink=1" class="new" title="Type II Na+-phosphate cotransporter (page does not exist)">type II Na<sup>+</sup>-phosphate cotransporter</a> <ul><li><a href="/wiki/SLC34A1" class="mw-redirect" title="SLC34A1">SLC34A1</a></li> <li><a href="/wiki/SLC34A2" class="mw-redirect" title="SLC34A2">SLC34A2</a></li> <li><a href="/wiki/SLC34A3" class="mw-redirect" title="SLC34A3">SLC34A3</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(35):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Nucleoside-sugar_transporter&action=edit&redlink=1" class="new" title="Nucleoside-sugar transporter (page does not exist)">nucleoside-sugar transporter</a> <ul><li><a href="/wiki/SLC35A1" class="mw-redirect" title="SLC35A1">SLC35A1</a></li> <li><a href="/wiki/SLC35A2" class="mw-redirect" title="SLC35A2">SLC35A2</a></li> <li><a href="/w/index.php?title=SLC35A3&action=edit&redlink=1" class="new" title="SLC35A3 (page does not exist)">SLC35A3</a></li> <li><a href="/w/index.php?title=SLC35A4&action=edit&redlink=1" class="new" title="SLC35A4 (page does not exist)">SLC35A4</a></li> <li><a href="/w/index.php?title=SLC35A5&action=edit&redlink=1" class="new" title="SLC35A5 (page does not exist)">SLC35A5</a></li></ul></li> <li> <ul><li><a href="/w/index.php?title=SLC35B1&action=edit&redlink=1" class="new" title="SLC35B1 (page does not exist)">SLC35B1</a></li> <li><a href="/wiki/SLC35B2" class="mw-redirect" title="SLC35B2">SLC35B2</a></li> <li><a href="/w/index.php?title=SLC35B3&action=edit&redlink=1" class="new" title="SLC35B3 (page does not exist)">SLC35B3</a></li> <li><a href="/wiki/SLC35B4" class="mw-redirect" title="SLC35B4">SLC35B4</a></li></ul></li> <li> <ul><li><a href="/wiki/SLC35C1" class="mw-redirect" title="SLC35C1">SLC35C1</a></li> <li><a href="/wiki/SLC35C2" title="SLC35C2">SLC35C2</a></li></ul></li> <li> <ul><li><a href="/w/index.php?title=SLC35D1&action=edit&redlink=1" class="new" title="SLC35D1 (page does not exist)">SLC35D1</a></li> <li><a href="/w/index.php?title=SLC35D2&action=edit&redlink=1" class="new" title="SLC35D2 (page does not exist)">SLC35D2</a></li> <li><a href="/w/index.php?title=SLC35D3&action=edit&redlink=1" class="new" title="SLC35D3 (page does not exist)">SLC35D3</a></li></ul></li> <li> <ul><li><a href="/w/index.php?title=SLC35E1&action=edit&redlink=1" class="new" title="SLC35E1 (page does not exist)">SLC35E1</a></li> <li><a href="/w/index.php?title=SLC35E2&action=edit&redlink=1" class="new" title="SLC35E2 (page does not exist)">SLC35E2</a></li> <li><a href="/w/index.php?title=SLC35E3&action=edit&redlink=1" class="new" title="SLC35E3 (page does not exist)">SLC35E3</a></li> <li><a href="/w/index.php?title=SLC35E4&action=edit&redlink=1" class="new" title="SLC35E4 (page does not exist)">SLC35E4</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(36):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Proton-coupled_amino-acid_transporter" class="mw-redirect" title="Proton-coupled amino-acid transporter">proton-coupled amino-acid transporter</a> <ul><li><a href="/wiki/SLC36A1" class="mw-redirect" title="SLC36A1">SLC36A1</a></li> <li><a href="/wiki/SLC36A2" class="mw-redirect" title="SLC36A2">SLC36A2</a></li> <li><a href="/w/index.php?title=SLC36A3&action=edit&redlink=1" class="new" title="SLC36A3 (page does not exist)">SLC36A3</a></li> <li><a href="/w/index.php?title=SLC36A4&action=edit&redlink=1" class="new" title="SLC36A4 (page does not exist)">SLC36A4</a><a href="/wiki/SLC36A2" class="mw-redirect" title="SLC36A2">36A2</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(37):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Sugar-phosphate/phosphate_exchanger&action=edit&redlink=1" class="new" title="Sugar-phosphate/phosphate exchanger (page does not exist)">sugar-phosphate/phosphate exchanger</a> <ul><li><a href="/wiki/SLC37A1" class="mw-redirect" title="SLC37A1">SLC37A1</a></li> <li><a href="/wiki/SLC37A2" class="mw-redirect" title="SLC37A2">SLC37A2</a></li> <li><a href="/w/index.php?title=SLC37A3&action=edit&redlink=1" class="new" title="SLC37A3 (page does not exist)">SLC37A3</a></li> <li><a href="/wiki/SLC37A4" class="mw-redirect" title="SLC37A4">SLC37A4</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(38):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=System_A_%26_N,_sodium-coupled_neutral_amino-acid_transporter&action=edit&redlink=1" class="new" title="System A & N, sodium-coupled neutral amino-acid transporter (page does not exist)">System A & N, sodium-coupled neutral amino-acid transporter</a> <ul><li><a href="/wiki/SLC38A1" title="SLC38A1">SLC38A1</a></li> <li><a href="/wiki/SLC38A2" class="mw-redirect" title="SLC38A2">SLC38A2</a></li> <li><a href="/wiki/SLC38A3" class="mw-redirect" title="SLC38A3">SLC38A3</a></li> <li><a href="/w/index.php?title=SLC38A4&action=edit&redlink=1" class="new" title="SLC38A4 (page does not exist)">SLC38A4</a></li> <li><a href="/wiki/SLC38A5" title="SLC38A5">SLC38A5</a></li> <li><a href="/w/index.php?title=SLC38A6&action=edit&redlink=1" class="new" title="SLC38A6 (page does not exist)">SLC38A6</a></li> <li><a href="/wiki/SLC38A10" class="mw-redirect" title="SLC38A10">SLC38A10</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(39):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Metal_ion_transporter" class="mw-redirect" title="Metal ion transporter">metal ion transporter</a> <ul><li><a href="/wiki/SLC39A1" class="mw-redirect" title="SLC39A1">SLC39A1</a></li> <li><a href="/wiki/SLC39A2" class="mw-redirect" title="SLC39A2">SLC39A2</a></li> <li><a href="/wiki/SLC39A3" class="mw-redirect" title="SLC39A3">SLC39A3</a></li> <li><a href="/wiki/SLC39A4" class="mw-redirect" title="SLC39A4">SLC39A4</a></li> <li><a href="/w/index.php?title=SLC39A5&action=edit&redlink=1" class="new" title="SLC39A5 (page does not exist)">SLC39A5</a></li> <li><a href="/wiki/SLC39A6" class="mw-redirect" title="SLC39A6">SLC39A6</a></li> <li><a href="/wiki/SLC39A7" class="mw-redirect" title="SLC39A7">SLC39A7</a></li> <li><a href="/wiki/SLC39A8" class="mw-redirect" title="SLC39A8">SLC39A8</a></li> <li><a href="/wiki/SLC39A9" class="mw-redirect" title="SLC39A9">SLC39A9</a></li> <li><a href="/wiki/SLC39A10" class="mw-redirect" title="SLC39A10">SLC39A10</a></li> <li><a href="/wiki/SLC39A11" title="SLC39A11">SLC39A11</a></li> <li><a href="/wiki/SLC39A12" class="mw-redirect" title="SLC39A12">SLC39A12</a></li> <li><a href="/w/index.php?title=SLC39A13&action=edit&redlink=1" class="new" title="SLC39A13 (page does not exist)">SLC39A13</a></li> <li><a href="/w/index.php?title=SLC39A14&action=edit&redlink=1" class="new" title="SLC39A14 (page does not exist)">SLC39A14</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(40):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Basolateral_iron_transporter&action=edit&redlink=1" class="new" title="Basolateral iron transporter (page does not exist)">basolateral iron transporter</a> <ul><li><a href="/wiki/Ferroportin" title="Ferroportin">SLC40A1</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="text-align:left; background-color: AntiqueWhite;"><div id="SLC41–48" style="font-size:114%;margin:0 4em">SLC41–48</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0;text-align:left;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(41):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Magnesium_transporter_E" title="Magnesium transporter E">Magnesium transporter E</a> <ul><li><a href="/wiki/SLC41A1" title="SLC41A1">SLC41A1</a></li> <li><a href="/w/index.php?title=SLC41A2&action=edit&redlink=1" class="new" title="SLC41A2 (page does not exist)">SLC41A2</a></li> <li><a href="/wiki/SLC41A3" title="SLC41A3">SLC41A3</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(42):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Ammonia_transporter" title="Ammonia transporter">Ammonia transporter</a> <ul><li><a href="/wiki/RHAG" title="RHAG">RhAG</a></li> <li><a href="/wiki/RHBG" title="RHBG">RhBG</a></li> <li><a href="/wiki/RHCG" title="RHCG">RhCG</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(43):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Na%2B-independent,_system-L_like_amino-acid_transporter&action=edit&redlink=1" class="new" title="Na+-independent, system-L like amino-acid transporter (page does not exist)">Na<sup>+</sup>-independent, system-L like amino-acid transporter</a> <ul><li><a href="/wiki/SLC43A1" class="mw-redirect" title="SLC43A1">SLC43A1</a></li> <li><a href="/w/index.php?title=SLC43A2&action=edit&redlink=1" class="new" title="SLC43A2 (page does not exist)">SLC43A2</a></li> <li><a href="/w/index.php?title=SLC43A3&action=edit&redlink=1" class="new" title="SLC43A3 (page does not exist)">SLC43A3</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(44):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Choline-like_transporter&action=edit&redlink=1" class="new" title="Choline-like transporter (page does not exist)">Choline-like transporter</a> <ul><li><a href="/wiki/SLC44A1" class="mw-redirect" title="SLC44A1">SLC44A1</a></li> <li><a href="/wiki/SLC44A2" class="mw-redirect" title="SLC44A2">SLC44A2</a></li> <li><a href="/w/index.php?title=SLC44A3&action=edit&redlink=1" class="new" title="SLC44A3 (page does not exist)">SLC44A3</a></li> <li><a href="/wiki/SLC44A4" class="mw-redirect" title="SLC44A4">SLC44A4</a></li> <li><a href="/w/index.php?title=SLC44A5&action=edit&redlink=1" class="new" title="SLC44A5 (page does not exist)">SLC44A5</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(45):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Putative_sugar_transporter&action=edit&redlink=1" class="new" title="Putative sugar transporter (page does not exist)">Putative sugar transporter</a> <ul><li><a href="/wiki/SLC45A1" title="SLC45A1">SLC45A1</a></li> <li><a href="/wiki/SLC45A2" class="mw-redirect" title="SLC45A2">SLC45A2</a></li> <li><a href="/w/index.php?title=SLC54A3&action=edit&redlink=1" class="new" title="SLC54A3 (page does not exist)">SLC54A3</a></li> <li><a href="/wiki/SLC45A4" title="SLC45A4">SLC45A4</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(46):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Folate_transporter&action=edit&redlink=1" class="new" title="Folate transporter (page does not exist)">Folate transporter</a> <ul><li><a href="/wiki/SLC46A1" class="mw-redirect" title="SLC46A1">SLC46A1</a></li> <li><a href="/w/index.php?title=SLC46A2&action=edit&redlink=1" class="new" title="SLC46A2 (page does not exist)">SLC46A2</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(47):</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Multi-antimicrobial_extrusion_protein" title="Multi-antimicrobial extrusion protein">multidrug and toxin extrusion</a> <ul><li><a href="/wiki/SLC47A1" class="mw-redirect" title="SLC47A1">SLC47A1</a></li> <li><a href="/wiki/SLC47A2" class="mw-redirect" title="SLC47A2">SLC47A2</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:right; background-color: AntiqueWhite;">(48):</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Heme_transporter" title="Heme transporter">Heme transporter</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="text-align:left; background-color: AntiqueWhite;"><div id="SLCO1–4" style="font-size:114%;margin:0 4em">SLCO1–4</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0;text-align:left;"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/SLCO1A2" class="mw-redirect" title="SLCO1A2">O1A2</a></li> <li><a href="/wiki/SLCO1B1" class="mw-redirect" title="SLCO1B1">O1B1</a></li> <li><a href="/wiki/SLCO1B3" class="mw-redirect" title="SLCO1B3">O1B3</a></li> <li><a href="/wiki/SLCO2B1" class="mw-redirect" title="SLCO2B1">O2B1</a></li> <li><a href="/wiki/SLCO3A1" class="mw-redirect" title="SLCO3A1">O431</a></li> <li><a href="/wiki/SLCO4A1" class="mw-redirect" title="SLCO4A1">O4A1</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background-color: AntiqueWhite;"><div id="Ion_pumps" style="font-size:114%;margin:0 4em"><a href="/wiki/Ion_transporter" title="Ion transporter">Ion pumps</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Symporter" title="Symporter">Symporter</a>, <a href="/wiki/Cotransporter" title="Cotransporter">Cotransporter</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Na-K-Cl_cotransporter" class="mw-redirect" title="Na-K-Cl cotransporter">Na<sup>+</sup>/K<sup>+</sup>,Cl<sup>−</sup></a></li> <li><a href="/wiki/Sodium/phosphate_cotransporter" title="Sodium/phosphate cotransporter">Na<sup>+</sup>/P<sub>i</sub>3</a></li> <li><a href="/wiki/Sodium-chloride_symporter" title="Sodium-chloride symporter">Na<sup>+</sup>/Cl<sup>−</sup></a></li> <li><a href="/wiki/Sodium-glucose_transport_proteins" title="Sodium-glucose transport proteins">Na<sup>+</sup>/glucose</a></li> <li><a href="/wiki/Sodium-iodide_symporter" class="mw-redirect" title="Sodium-iodide symporter">Na<sup>+</sup>/I<sup>−</sup></a></li> <li><a href="/wiki/Chloride_potassium_symporter" title="Chloride potassium symporter">Cl<sup>−</sup>/K<sup>+</sup></a> <ul><li><a href="/wiki/Chloride_potassium_symporter_4" title="Chloride potassium symporter 4">4</a></li> <li><a href="/wiki/Chloride_potassium_symporter_5" title="Chloride potassium symporter 5">5</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Antiporter" title="Antiporter">Antiporter (exchanger)</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Sodium%E2%80%93hydrogen_antiporter" title="Sodium–hydrogen antiporter">Na<sup>+</sup>/H<sup>+</sup></a></li> <li><a href="/wiki/Sodium-calcium_exchanger" title="Sodium-calcium exchanger">Na<sup>+</sup>/Ca<sup>2+</sup></a> <ul><li><a href="/wiki/Potassium-dependent_sodium-calcium_exchanger" title="Potassium-dependent sodium-calcium exchanger">Na<sup>+</sup>/(Ca<sup>2+</sup>-K<sup>+</sup></a>) - <a href="/wiki/Band_3" class="mw-redirect" title="Band 3">Cl<sup>−</sup>/<span class="chemf nowrap">HCO<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline">−</sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">3</sub></span></span></span> (Band 3)</a></li></ul></li> <li><a href="/wiki/Cl-formate_exchanger" class="mw-redirect" title="Cl-formate exchanger">Cl<sup>−</sup>-formate</a></li> <li><a href="/wiki/Cl-oxalate_exchanger" title="Cl-oxalate exchanger">Cl<sup>−</sup>-oxalate</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background-color: AntiqueWhite; padding: 0px;"><div><i>see also <a href="/wiki/Template:Solute_carrier_disorders" title="Template:Solute carrier disorders">solute carrier disorders</a></i></div></td></tr></tbody></table></div> <!-- NewPP limit report Parsed by mw‐web.codfw.main‐f69cdc8f6‐zdfpm Cached time: 20241122142843 Cache expiry: 2592000 Reduced expiry: false Complications: [vary‐revision‐sha1, show‐toc] CPU time usage: 0.459 seconds Real time usage: 0.539 seconds Preprocessor visited node count: 2605/1000000 Post‐expand include size: 199513/2097152 bytes Template argument size: 1713/2097152 bytes Highest expansion depth: 19/100 Expensive parser function count: 1/500 Unstrip recursion depth: 1/20 Unstrip post‐expand size: 78691/5000000 bytes Lua time usage: 0.250/10.000 seconds Lua memory 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