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(PDF) Sex differences in asthma symptom profiles and control in the American Lung Association Asthma Clinical Research Centers | Janet Holbrook - Academia.edu
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"https://www.academia.edu/login?post_login_redirect_url=https%3A%2F%2Fwww.academia.edu%2F120266407%2FSex_differences_in_asthma_symptom_profiles_and_control_in_the_American_Lung_Association_Asthma_Clinical_Research_Centers%3Fshow_translation%3Dtrue"; window.loswp.previewableAttachments = [{"id":115473707,"identifier":"Attachment_115473707","shouldShowBulkDownload":false}]; window.loswp.shouldDetectTimezone = true; window.loswp.shouldShowBulkDownload = true; window.loswp.showSignupCaptcha = false window.loswp.willEdgeCache = false; window.loswp.work = {"work":{"id":120266407,"created_at":"2024-05-30T05:21:38.681-07:00","from_world_paper_id":255343758,"updated_at":"2024-11-23T05:41:03.158-08:00","_data":{"publisher":"Elsevier BV","grobid_abstract":"Important differences between men and women with asthma have been demonstrated, with women describing more symptoms and worse asthma-related quality of life (QOL) despite having similar or better pulmonary function. While current guidelines focus heavily on assessing asthma control, they lack information about whether sex-specific approaches to asthma assessment should be considered. We sought to determine if sex differences in asthma control or symptom profiles exist in the well-characterized population of participants in the American Lung Association Asthma Clinical Research Centers (ALA-ACRC) trials. Methods: We reviewed baseline data from four trials published by the ALA-ACRC to evaluate individual item responses to three standardized asthma questionnaires: the Juniper Asthma Control Questionnaire (ACQ), the multi-attribute Asthma Symptom Utility Index (ASUI), and Juniper Mini Asthma Quality of Life Questionnaire (mini-AQLQ). Results: In the poorly-controlled population, women reported similar overall asthma control (mean ACQ 1.9 vs. 1.8; p Z 0.54), but were more likely to report specific symptoms such as nocturnal awakenings, activity limitations, and shortness of breath on individual item responses. Women reported worse asthma-related QOL on the mini-AQLQ (mean 4.5 vs. 4.9; p \u003c 0.001) and more asthma-related symptoms with a lower mean score on the ASUI (0.73 vs. 0.77; p 0.0001) and were more likely to report feeling bothered by particular symptoms such as coughing, or environmental triggers. Conclusions: In participants with poorly-controlled asthma, women had outwardly similar asthma control, but had unique symptom profiles on detailed item analyses which were evident on evaluation of three standardized asthma questionnaires.","publication_date":"2013,,","publication_name":"Respiratory Medicine","grobid_abstract_attachment_id":"115473707"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Sex differences in asthma symptom profiles and control in the American Lung Association Asthma Clinical Research Centers","broadcastable":false,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [47897762]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; 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