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class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Modern_era"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.1</span> <span>Modern era</span> </div> </a> <ul id="toc-Modern_era-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-21st_century" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#21st_century"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.2</span> <span>21st century</span> </div> </a> <ul id="toc-21st_century-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Types_of_studies" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#Types_of_studies"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Types of studies</span> </div> </a> <button aria-controls="toc-Types_of_studies-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon 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<span>Cohort studies</span> </div> </a> <ul id="toc-Cohort_studies-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Causal_inference" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#Causal_inference"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Causal inference</span> </div> </a> <button aria-controls="toc-Causal_inference-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Causal inference subsection</span> </button> <ul id="toc-Causal_inference-sublist" class="vector-toc-list"> <li id="toc-Bradford_Hill_criteria" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Bradford_Hill_criteria"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.1</span> <span>Bradford Hill criteria</span> </div> </a> <ul id="toc-Bradford_Hill_criteria-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Legal_interpretation" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Legal_interpretation"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.2</span> <span>Legal interpretation</span> </div> </a> <ul id="toc-Legal_interpretation-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Population-based_health_management" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#Population-based_health_management"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Population-based health management</span> </div> </a> <ul id="toc-Population-based_health_management-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Applied_field_epidemiology" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#Applied_field_epidemiology"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Applied field epidemiology</span> </div> </a> <button aria-controls="toc-Applied_field_epidemiology-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Applied field epidemiology subsection</span> </button> <ul id="toc-Applied_field_epidemiology-sublist" class="vector-toc-list"> <li id="toc-Humanitarian_context" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Humanitarian_context"> <div class="vector-toc-text"> <span class="vector-toc-numb">5.1</span> <span>Humanitarian context</span> </div> </a> <ul id="toc-Humanitarian_context-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Characterization,_validity,_and_bias" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#Characterization,_validity,_and_bias"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>Characterization, validity, and bias</span> </div> </a> <button aria-controls="toc-Characterization,_validity,_and_bias-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Characterization, validity, and bias subsection</span> </button> <ul id="toc-Characterization,_validity,_and_bias-sublist" class="vector-toc-list"> <li id="toc-Epidemic_wave" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Epidemic_wave"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.1</span> <span>Epidemic wave</span> </div> </a> <ul id="toc-Epidemic_wave-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Validities" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Validities"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.2</span> <span>Validities</span> </div> </a> <ul id="toc-Validities-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Random_error" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Random_error"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.3</span> <span>Random error</span> </div> </a> <ul id="toc-Random_error-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Systematic_error" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Systematic_error"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.4</span> <span>Systematic error</span> </div> </a> <ul id="toc-Systematic_error-sublist" class="vector-toc-list"> <li id="toc-Selection_bias" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Selection_bias"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.4.1</span> <span>Selection bias</span> </div> </a> <ul id="toc-Selection_bias-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Information_bias" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Information_bias"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.4.2</span> <span>Information bias</span> </div> </a> <ul id="toc-Information_bias-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Design-related_bias" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Design-related_bias"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.4.3</span> <span>Design-related bias</span> </div> </a> <ul id="toc-Design-related_bias-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Confounding" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Confounding"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.4.4</span> <span>Confounding</span> </div> </a> <ul id="toc-Confounding-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> </ul> </li> <li id="toc-The_profession" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#The_profession"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>The profession</span> </div> </a> <button aria-controls="toc-The_profession-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle The profession subsection</span> </button> <ul id="toc-The_profession-sublist" class="vector-toc-list"> <li id="toc-COVID-19" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#COVID-19"> <div class="vector-toc-text"> <span class="vector-toc-numb">7.1</span> <span>COVID-19</span> </div> </a> <ul id="toc-COVID-19-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-See_also" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#See_also"> <div class="vector-toc-text"> <span class="vector-toc-numb">8</span> <span>See also</span> </div> </a> <ul id="toc-See_also-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">9</span> <span>References</span> </div> </a> <button aria-controls="toc-References-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle References subsection</span> </button> <ul id="toc-References-sublist" class="vector-toc-list"> <li id="toc-Citations" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Citations"> <div class="vector-toc-text"> <span class="vector-toc-numb">9.1</span> <span>Citations</span> </div> </a> <ul id="toc-Citations-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Sources" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Sources"> <div class="vector-toc-text"> <span class="vector-toc-numb">9.2</span> <span>Sources</span> </div> </a> <ul id="toc-Sources-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-External_links" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#External_links"> <div class="vector-toc-text"> <span class="vector-toc-numb">10</span> <span>External links</span> </div> </a> <ul id="toc-External_links-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contents" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" title="Table of Contents" > <input type="checkbox" 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id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. Available in 80 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-80" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">80 languages</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-af mw-list-item"><a href="https://af.wikipedia.org/wiki/Epidemiologie" title="Epidemiologie – Afrikaans" lang="af" hreflang="af" data-title="Epidemiologie" data-language-autonym="Afrikaans" data-language-local-name="Afrikaans" class="interlanguage-link-target"><span>Afrikaans</span></a></li><li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%88%D8%A8%D8%A7%D8%A6%D9%8A%D8%A7%D8%AA" title="وبائيات – Arabic" lang="ar" hreflang="ar" data-title="وبائيات" data-language-autonym="العربية" data-language-local-name="Arabic" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-az mw-list-item"><a href="https://az.wikipedia.org/wiki/Epidemiologiya" title="Epidemiologiya – Azerbaijani" lang="az" hreflang="az" data-title="Epidemiologiya" data-language-autonym="Azərbaycanca" data-language-local-name="Azerbaijani" class="interlanguage-link-target"><span>Azərbaycanca</span></a></li><li class="interlanguage-link interwiki-bn mw-list-item"><a href="https://bn.wikipedia.org/wiki/%E0%A6%B0%E0%A7%8B%E0%A6%97%E0%A6%AC%E0%A6%BF%E0%A6%B8%E0%A7%8D%E0%A6%A4%E0%A6%BE%E0%A6%B0_%E0%A6%AC%E0%A6%BF%E0%A6%9C%E0%A7%8D%E0%A6%9E%E0%A6%BE%E0%A6%A8" title="রোগবিস্তার বিজ্ঞান – Bangla" lang="bn" hreflang="bn" data-title="রোগবিস্তার বিজ্ঞান" data-language-autonym="বাংলা" data-language-local-name="Bangla" class="interlanguage-link-target"><span>বাংলা</span></a></li><li class="interlanguage-link interwiki-zh-min-nan mw-list-item"><a href="https://zh-min-nan.wikipedia.org/wiki/Li%C3%BB-h%C3%AAng-p%C4%93%E2%81%BF-ha%CC%8Dk" title="Liû-hêng-pēⁿ-ha̍k – Minnan" lang="nan" hreflang="nan" data-title="Liû-hêng-pēⁿ-ha̍k" data-language-autonym="閩南語 / Bân-lâm-gú" data-language-local-name="Minnan" class="interlanguage-link-target"><span>閩南語 / Bân-lâm-gú</span></a></li><li class="interlanguage-link interwiki-be mw-list-item"><a href="https://be.wikipedia.org/wiki/%D0%AD%D0%BF%D1%96%D0%B4%D1%8D%D0%BC%D1%96%D1%8F%D0%BB%D0%BE%D0%B3%D1%96%D1%8F" title="Эпідэміялогія – Belarusian" lang="be" hreflang="be" data-title="Эпідэміялогія" data-language-autonym="Беларуская" data-language-local-name="Belarusian" class="interlanguage-link-target"><span>Беларуская</span></a></li><li class="interlanguage-link interwiki-be-x-old mw-list-item"><a href="https://be-tarask.wikipedia.org/wiki/%D0%AD%D0%BF%D1%96%D0%B4%D1%8D%D0%BC%D1%96%D1%8F%D0%BB%D1%91%D0%B3%D1%96%D1%8F" title="Эпідэміялёгія – Belarusian (Taraškievica orthography)" lang="be-tarask" hreflang="be-tarask" data-title="Эпідэміялёгія" data-language-autonym="Беларуская (тарашкевіца)" data-language-local-name="Belarusian (Taraškievica orthography)" class="interlanguage-link-target"><span>Беларуская (тарашкевіца)</span></a></li><li class="interlanguage-link interwiki-bcl mw-list-item"><a href="https://bcl.wikipedia.org/wiki/Epidemyolohiya" title="Epidemyolohiya – Central Bikol" lang="bcl" hreflang="bcl" data-title="Epidemyolohiya" data-language-autonym="Bikol Central" data-language-local-name="Central Bikol" class="interlanguage-link-target"><span>Bikol Central</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%95%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F" title="Епидемиология – Bulgarian" lang="bg" hreflang="bg" data-title="Епидемиология" data-language-autonym="Български" data-language-local-name="Bulgarian" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Epidemiologija" title="Epidemiologija – Bosnian" lang="bs" hreflang="bs" data-title="Epidemiologija" data-language-autonym="Bosanski" data-language-local-name="Bosnian" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Epidemiologia" title="Epidemiologia – Catalan" lang="ca" hreflang="ca" data-title="Epidemiologia" data-language-autonym="Català" data-language-local-name="Catalan" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Epidemiologie" title="Epidemiologie – Czech" lang="cs" hreflang="cs" data-title="Epidemiologie" data-language-autonym="Čeština" data-language-local-name="Czech" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/Epidemiologi" title="Epidemiologi – Danish" lang="da" hreflang="da" data-title="Epidemiologi" data-language-autonym="Dansk" data-language-local-name="Danish" class="interlanguage-link-target"><span>Dansk</span></a></li><li class="interlanguage-link interwiki-de badge-Q17437798 badge-goodarticle mw-list-item" title="good article badge"><a href="https://de.wikipedia.org/wiki/Epidemiologie" title="Epidemiologie – German" lang="de" hreflang="de" data-title="Epidemiologie" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/Epidemioloogia" title="Epidemioloogia – Estonian" lang="et" hreflang="et" data-title="Epidemioloogia" data-language-autonym="Eesti" data-language-local-name="Estonian" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%95%CF%80%CE%B9%CE%B4%CE%B7%CE%BC%CE%B9%CE%BF%CE%BB%CE%BF%CE%B3%CE%AF%CE%B1" title="Επιδημιολογία – Greek" lang="el" hreflang="el" data-title="Επιδημιολογία" data-language-autonym="Ελληνικά" data-language-local-name="Greek" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Epidemiolog%C3%ADa" title="Epidemiología – Spanish" lang="es" hreflang="es" data-title="Epidemiología" data-language-autonym="Español" data-language-local-name="Spanish" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Epidemiologio" title="Epidemiologio – Esperanto" lang="eo" hreflang="eo" data-title="Epidemiologio" data-language-autonym="Esperanto" data-language-local-name="Esperanto" class="interlanguage-link-target"><span>Esperanto</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Epidemiologia" title="Epidemiologia – Basque" lang="eu" hreflang="eu" data-title="Epidemiologia" data-language-autonym="Euskara" data-language-local-name="Basque" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%87%D9%85%D9%87%E2%80%8C%DA%AF%DB%8C%D8%B1%D8%B4%D9%86%D8%A7%D8%B3%DB%8C" title="همه‌گیرشناسی – Persian" lang="fa" hreflang="fa" data-title="همه‌گیرشناسی" data-language-autonym="فارسی" data-language-local-name="Persian" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/%C3%89pid%C3%A9miologie" title="Épidémiologie – French" lang="fr" hreflang="fr" data-title="Épidémiologie" data-language-autonym="Français" data-language-local-name="French" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-ga mw-list-item"><a href="https://ga.wikipedia.org/wiki/Eipid%C3%A9imeola%C3%ADocht" title="Eipidéimeolaíocht – Irish" lang="ga" hreflang="ga" data-title="Eipidéimeolaíocht" data-language-autonym="Gaeilge" data-language-local-name="Irish" class="interlanguage-link-target"><span>Gaeilge</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Epidemiolox%C3%ADa" title="Epidemioloxía – Galician" lang="gl" hreflang="gl" data-title="Epidemioloxía" data-language-autonym="Galego" data-language-local-name="Galician" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EC%97%AD%ED%95%99_(%EC%9D%98%ED%95%99)" title="역학 (의학) – Korean" lang="ko" hreflang="ko" data-title="역학 (의학)" data-language-autonym="한국어" data-language-local-name="Korean" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D5%80%D5%A1%D5%B4%D5%A1%D5%B3%D5%A1%D6%80%D5%A1%D5%AF%D5%A1%D5%A2%D5%A1%D5%B6%D5%B8%D6%82%D5%A9%D5%B5%D5%B8%D6%82%D5%B6" title="Համաճարակաբանություն – Armenian" lang="hy" hreflang="hy" data-title="Համաճարակաբանություն" data-language-autonym="Հայերեն" data-language-local-name="Armenian" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%AE%E0%A4%B9%E0%A4%BE%E0%A4%AE%E0%A4%BE%E0%A4%B0%E0%A5%80_%E0%A4%B5%E0%A4%BF%E0%A4%9C%E0%A5%8D%E0%A4%9E%E0%A4%BE%E0%A4%A8" title="महामारी विज्ञान – Hindi" lang="hi" hreflang="hi" data-title="महामारी विज्ञान" data-language-autonym="हिन्दी" data-language-local-name="Hindi" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Epidemiologija" title="Epidemiologija – Croatian" lang="hr" hreflang="hr" data-title="Epidemiologija" data-language-autonym="Hrvatski" data-language-local-name="Croatian" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Epidemiologi" title="Epidemiologi – Indonesian" lang="id" hreflang="id" data-title="Epidemiologi" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonesian" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-ia mw-list-item"><a href="https://ia.wikipedia.org/wiki/Epidemiologia" title="Epidemiologia – Interlingua" lang="ia" hreflang="ia" data-title="Epidemiologia" data-language-autonym="Interlingua" data-language-local-name="Interlingua" class="interlanguage-link-target"><span>Interlingua</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Epidemiologia" title="Epidemiologia – Italian" lang="it" hreflang="it" data-title="Epidemiologia" data-language-autonym="Italiano" data-language-local-name="Italian" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%90%D7%A4%D7%99%D7%93%D7%9E%D7%99%D7%95%D7%9C%D7%95%D7%92%D7%99%D7%94" title="אפידמיולוגיה – Hebrew" lang="he" hreflang="he" data-title="אפידמיולוגיה" data-language-autonym="עברית" data-language-local-name="Hebrew" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-kn mw-list-item"><a href="https://kn.wikipedia.org/wiki/%E0%B2%B8%E0%B2%BE%E0%B2%82%E0%B2%95%E0%B3%8D%E0%B2%B0%E0%B2%BE%E0%B2%AE%E0%B2%BF%E0%B2%95_%E0%B2%B0%E0%B3%8B%E0%B2%97%E0%B2%B5%E0%B2%BF%E0%B2%9C%E0%B3%8D%E0%B2%9E%E0%B2%BE%E0%B2%A8" title="ಸಾಂಕ್ರಾಮಿಕ ರೋಗವಿಜ್ಞಾನ – Kannada" lang="kn" hreflang="kn" data-title="ಸಾಂಕ್ರಾಮಿಕ ರೋಗವಿಜ್ಞಾನ" data-language-autonym="ಕನ್ನಡ" data-language-local-name="Kannada" class="interlanguage-link-target"><span>ಕನ್ನಡ</span></a></li><li class="interlanguage-link interwiki-ka mw-list-item"><a href="https://ka.wikipedia.org/wiki/%E1%83%94%E1%83%9E%E1%83%98%E1%83%93%E1%83%94%E1%83%9B%E1%83%98%E1%83%9D%E1%83%9A%E1%83%9D%E1%83%92%E1%83%98%E1%83%90" title="ეპიდემიოლოგია – Georgian" lang="ka" hreflang="ka" data-title="ეპიდემიოლოგია" data-language-autonym="ქართული" data-language-local-name="Georgian" class="interlanguage-link-target"><span>ქართული</span></a></li><li class="interlanguage-link interwiki-kk mw-list-item"><a href="https://kk.wikipedia.org/wiki/%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F" title="Эпидемиология – Kazakh" lang="kk" hreflang="kk" data-title="Эпидемиология" data-language-autonym="Қазақша" data-language-local-name="Kazakh" class="interlanguage-link-target"><span>Қазақша</span></a></li><li class="interlanguage-link interwiki-ku mw-list-item"><a href="https://ku.wikipedia.org/wiki/Ep%C3%AEdem%C3%AEoloj%C3%AE" title="Epîdemîolojî – Kurdish" lang="ku" hreflang="ku" data-title="Epîdemîolojî" data-language-autonym="Kurdî" data-language-local-name="Kurdish" class="interlanguage-link-target"><span>Kurdî</span></a></li><li class="interlanguage-link interwiki-ky mw-list-item"><a href="https://ky.wikipedia.org/wiki/%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F" title="Эпидемиология – Kyrgyz" lang="ky" hreflang="ky" data-title="Эпидемиология" data-language-autonym="Кыргызча" data-language-local-name="Kyrgyz" class="interlanguage-link-target"><span>Кыргызча</span></a></li><li class="interlanguage-link interwiki-lv mw-list-item"><a href="https://lv.wikipedia.org/wiki/Epidemiolo%C4%A3ija" title="Epidemioloģija – Latvian" lang="lv" hreflang="lv" data-title="Epidemioloģija" data-language-autonym="Latviešu" data-language-local-name="Latvian" class="interlanguage-link-target"><span>Latviešu</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Epidemiologija" title="Epidemiologija – Lithuanian" lang="lt" hreflang="lt" data-title="Epidemiologija" data-language-autonym="Lietuvių" data-language-local-name="Lithuanian" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/J%C3%A1rv%C3%A1nytan" title="Járványtan – Hungarian" lang="hu" hreflang="hu" data-title="Járványtan" data-language-autonym="Magyar" data-language-local-name="Hungarian" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%95%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%98%D0%B0" title="Епидемиологија – Macedonian" lang="mk" hreflang="mk" data-title="Епидемиологија" data-language-autonym="Македонски" data-language-local-name="Macedonian" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-ml mw-list-item"><a href="https://ml.wikipedia.org/wiki/%E0%B4%B8%E0%B4%BE%E0%B4%82%E0%B4%95%E0%B5%8D%E0%B4%B0%E0%B4%AE%E0%B4%BF%E0%B4%95%E0%B4%B0%E0%B5%8B%E0%B4%97%E0%B4%B5%E0%B4%BF%E0%B4%9C%E0%B5%8D%E0%B4%9E%E0%B4%BE%E0%B4%A8%E0%B5%80%E0%B4%AF%E0%B4%82" title="സാംക്രമികരോഗവിജ്ഞാനീയം – Malayalam" lang="ml" hreflang="ml" data-title="സാംക്രമികരോഗവിജ്ഞാനീയം" data-language-autonym="മലയാളം" data-language-local-name="Malayalam" class="interlanguage-link-target"><span>മലയാളം</span></a></li><li class="interlanguage-link interwiki-arz mw-list-item"><a href="https://arz.wikipedia.org/wiki/%D8%A7%D9%8A%D8%A8%D9%8A%D8%AF%D9%8A%D9%85%D9%8A%D9%88%D9%84%D9%88%D8%AC%D9%8A%D8%A7" title="ايبيديميولوجيا – Egyptian Arabic" lang="arz" hreflang="arz" data-title="ايبيديميولوجيا" data-language-autonym="مصرى" data-language-local-name="Egyptian Arabic" class="interlanguage-link-target"><span>مصرى</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Epidemiologi" title="Epidemiologi – Malay" lang="ms" hreflang="ms" data-title="Epidemiologi" data-language-autonym="Bahasa Melayu" data-language-local-name="Malay" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-min mw-list-item"><a href="https://min.wikipedia.org/wiki/Epidemiologi" title="Epidemiologi – Minangkabau" lang="min" hreflang="min" data-title="Epidemiologi" data-language-autonym="Minangkabau" data-language-local-name="Minangkabau" class="interlanguage-link-target"><span>Minangkabau</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Epidemiologie" title="Epidemiologie – Dutch" lang="nl" hreflang="nl" data-title="Epidemiologie" data-language-autonym="Nederlands" data-language-local-name="Dutch" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-ne mw-list-item"><a href="https://ne.wikipedia.org/wiki/%E0%A4%AE%E0%A4%B9%E0%A4%BE%E0%A4%AE%E0%A4%BE%E0%A4%B0%E0%A5%80_%E0%A4%B5%E0%A4%BF%E0%A4%9C%E0%A5%8D%E0%A4%9E%E0%A4%BE%E0%A4%A8" title="महामारी विज्ञान – Nepali" lang="ne" hreflang="ne" data-title="महामारी विज्ञान" data-language-autonym="नेपाली" data-language-local-name="Nepali" class="interlanguage-link-target"><span>नेपाली</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E7%96%AB%E5%AD%A6" title="疫学 – Japanese" lang="ja" hreflang="ja" data-title="疫学" data-language-autonym="日本語" data-language-local-name="Japanese" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Epidemiologi" title="Epidemiologi – Norwegian Bokmål" lang="nb" hreflang="nb" data-title="Epidemiologi" data-language-autonym="Norsk bokmål" data-language-local-name="Norwegian Bokmål" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-uz mw-list-item"><a href="https://uz.wikipedia.org/wiki/Epidemiologiya" title="Epidemiologiya – Uzbek" lang="uz" hreflang="uz" data-title="Epidemiologiya" data-language-autonym="Oʻzbekcha / ўзбекча" data-language-local-name="Uzbek" class="interlanguage-link-target"><span>Oʻzbekcha / ўзбекча</span></a></li><li class="interlanguage-link interwiki-ps mw-list-item"><a href="https://ps.wikipedia.org/wiki/%D8%A7%D9%BE%D9%8A%DA%89%D9%8A%D9%85%D9%88%D9%84%D9%88%DA%98%D9%8A" title="اپيډيمولوژي – Pashto" lang="ps" hreflang="ps" data-title="اپيډيمولوژي" data-language-autonym="پښتو" data-language-local-name="Pashto" class="interlanguage-link-target"><span>پښتو</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Epidemiologia" title="Epidemiologia – Polish" lang="pl" hreflang="pl" data-title="Epidemiologia" data-language-autonym="Polski" data-language-local-name="Polish" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Epidemiologia" title="Epidemiologia – Portuguese" lang="pt" hreflang="pt" data-title="Epidemiologia" data-language-autonym="Português" data-language-local-name="Portuguese" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Epidemiologie" title="Epidemiologie – Romanian" lang="ro" hreflang="ro" data-title="Epidemiologie" data-language-autonym="Română" data-language-local-name="Romanian" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F" title="Эпидемиология – Russian" lang="ru" hreflang="ru" data-title="Эпидемиология" data-language-autonym="Русский" data-language-local-name="Russian" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sa mw-list-item"><a href="https://sa.wikipedia.org/wiki/%E0%A4%B0%E0%A5%8B%E0%A4%97%E0%A4%B6%E0%A4%BE%E0%A4%B8%E0%A5%8D%E0%A4%A4%E0%A5%8D%E0%A4%B0%E0%A4%AE%E0%A5%8D" title="रोगशास्त्रम् – Sanskrit" lang="sa" hreflang="sa" data-title="रोगशास्त्रम्" data-language-autonym="संस्कृतम्" data-language-local-name="Sanskrit" class="interlanguage-link-target"><span>संस्कृतम्</span></a></li><li class="interlanguage-link interwiki-sq mw-list-item"><a href="https://sq.wikipedia.org/wiki/Epidemiologjia" title="Epidemiologjia – Albanian" lang="sq" hreflang="sq" data-title="Epidemiologjia" data-language-autonym="Shqip" data-language-local-name="Albanian" class="interlanguage-link-target"><span>Shqip</span></a></li><li class="interlanguage-link interwiki-si mw-list-item"><a href="https://si.wikipedia.org/wiki/%E0%B7%80%E0%B7%83%E0%B6%82%E0%B6%9C%E0%B6%AD%E0%B7%80%E0%B7%9A%E0%B6%AF%E0%B6%BA" title="වසංගතවේදය – Sinhala" lang="si" hreflang="si" data-title="වසංගතවේදය" data-language-autonym="සිංහල" data-language-local-name="Sinhala" class="interlanguage-link-target"><span>සිංහල</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Epidemiology" title="Epidemiology – Simple English" lang="en-simple" hreflang="en-simple" data-title="Epidemiology" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sd mw-list-item"><a href="https://sd.wikipedia.org/wiki/%D8%A7%D9%8A%D9%BE%D9%8A%DA%8A%D9%8A%D9%85%D9%8A%D9%88%D9%84%D9%88%D8%AC%D9%8A" title="ايپيڊيميولوجي – Sindhi" lang="sd" hreflang="sd" data-title="ايپيڊيميولوجي" data-language-autonym="سنڌي" data-language-local-name="Sindhi" class="interlanguage-link-target"><span>سنڌي</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Epidemiol%C3%B3gia" title="Epidemiológia – Slovak" lang="sk" hreflang="sk" data-title="Epidemiológia" data-language-autonym="Slovenčina" data-language-local-name="Slovak" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Epidemiologija" title="Epidemiologija – Slovenian" lang="sl" hreflang="sl" data-title="Epidemiologija" data-language-autonym="Slovenščina" data-language-local-name="Slovenian" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/%D0%95%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%98%D0%B0" title="Епидемиологија – Serbian" lang="sr" hreflang="sr" data-title="Епидемиологија" data-language-autonym="Српски / srpski" data-language-local-name="Serbian" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Epidemiologija" title="Epidemiologija – Serbo-Croatian" lang="sh" hreflang="sh" data-title="Epidemiologija" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="Serbo-Croatian" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Epidemiologia" title="Epidemiologia – Finnish" lang="fi" hreflang="fi" data-title="Epidemiologia" data-language-autonym="Suomi" data-language-local-name="Finnish" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Epidemiologi" title="Epidemiologi – Swedish" lang="sv" hreflang="sv" data-title="Epidemiologi" data-language-autonym="Svenska" data-language-local-name="Swedish" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-tl mw-list-item"><a href="https://tl.wikipedia.org/wiki/Epidemiyolohiya" title="Epidemiyolohiya – Tagalog" lang="tl" hreflang="tl" data-title="Epidemiyolohiya" data-language-autonym="Tagalog" data-language-local-name="Tagalog" class="interlanguage-link-target"><span>Tagalog</span></a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a href="https://ta.wikipedia.org/wiki/%E0%AE%A8%E0%AF%8B%E0%AE%AF%E0%AF%8D%E0%AE%AA%E0%AF%8D%E0%AE%AA%E0%AE%B0%E0%AE%B5%E0%AE%B2%E0%AE%BF%E0%AE%AF%E0%AE%B2%E0%AF%8D" title="நோய்ப்பரவலியல் – Tamil" lang="ta" hreflang="ta" data-title="நோய்ப்பரவலியல்" data-language-autonym="தமிழ்" data-language-local-name="Tamil" class="interlanguage-link-target"><span>தமிழ்</span></a></li><li class="interlanguage-link interwiki-kab mw-list-item"><a href="https://kab.wikipedia.org/wiki/Tasensakrart" title="Tasensakrart – Kabyle" lang="kab" hreflang="kab" data-title="Tasensakrart" data-language-autonym="Taqbaylit" data-language-local-name="Kabyle" class="interlanguage-link-target"><span>Taqbaylit</span></a></li><li class="interlanguage-link interwiki-tt mw-list-item"><a href="https://tt.wikipedia.org/wiki/%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F" title="Эпидемиология – Tatar" lang="tt" hreflang="tt" data-title="Эпидемиология" data-language-autonym="Татарча / tatarça" data-language-local-name="Tatar" class="interlanguage-link-target"><span>Татарча / tatarça</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B8%A7%E0%B8%B4%E0%B8%97%E0%B8%A2%E0%B8%B2%E0%B8%81%E0%B8%B2%E0%B8%A3%E0%B8%A3%E0%B8%B0%E0%B8%9A%E0%B8%B2%E0%B8%94" title="วิทยาการระบาด – Thai" lang="th" hreflang="th" data-title="วิทยาการระบาด" data-language-autonym="ไทย" data-language-local-name="Thai" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Epidemiyoloji" title="Epidemiyoloji – Turkish" lang="tr" hreflang="tr" data-title="Epidemiyoloji" data-language-autonym="Türkçe" data-language-local-name="Turkish" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%95%D0%BF%D1%96%D0%B4%D0%B5%D0%BC%D1%96%D0%BE%D0%BB%D0%BE%D0%B3%D1%96%D1%8F" title="Епідеміологія – Ukrainian" lang="uk" hreflang="uk" data-title="Епідеміологія" data-language-autonym="Українська" data-language-local-name="Ukrainian" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-vec mw-list-item"><a href="https://vec.wikipedia.org/wiki/Epidemio%C5%82ozia" title="Epidemiołozia – Venetian" lang="vec" hreflang="vec" data-title="Epidemiołozia" data-language-autonym="Vèneto" data-language-local-name="Venetian" class="interlanguage-link-target"><span>Vèneto</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/D%E1%BB%8Bch_t%E1%BB%85_h%E1%BB%8Dc" title="Dịch tễ học – Vietnamese" lang="vi" hreflang="vi" data-title="Dịch tễ học" data-language-autonym="Tiếng Việt" data-language-local-name="Vietnamese" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-wa mw-list-item"><a href="https://wa.wikipedia.org/wiki/Min%C3%AAyolodjince" title="Minêyolodjince – Walloon" lang="wa" hreflang="wa" data-title="Minêyolodjince" data-language-autonym="Walon" data-language-local-name="Walloon" class="interlanguage-link-target"><span>Walon</span></a></li><li class="interlanguage-link interwiki-war mw-list-item"><a href="https://war.wikipedia.org/wiki/Epidemiyolohiya" title="Epidemiyolohiya – Waray" lang="war" hreflang="war" data-title="Epidemiyolohiya" data-language-autonym="Winaray" data-language-local-name="Waray" class="interlanguage-link-target"><span>Winaray</span></a></li><li class="interlanguage-link interwiki-wuu mw-list-item"><a href="https://wuu.wikipedia.org/wiki/%E6%B5%81%E8%A1%8C%E7%97%85%E5%AD%A6" title="流行病学 – Wu" lang="wuu" hreflang="wuu" data-title="流行病学" data-language-autonym="吴语" data-language-local-name="Wu" class="interlanguage-link-target"><span>吴语</span></a></li><li class="interlanguage-link interwiki-yo mw-list-item"><a href="https://yo.wikipedia.org/wiki/%C3%8Cm%E1%BB%8D%CC%80_%C3%A0j%C3%A0k%C3%A1l%E1%BA%B9%CC%80-%C3%A0r%C3%B9n" title="Ìmọ̀ àjàkálẹ̀-àrùn – Yoruba" lang="yo" hreflang="yo" data-title="Ìmọ̀ àjàkálẹ̀-àrùn" data-language-autonym="Yorùbá" data-language-local-name="Yoruba" class="interlanguage-link-target"><span>Yorùbá</span></a></li><li class="interlanguage-link interwiki-zh-yue mw-list-item"><a href="https://zh-yue.wikipedia.org/wiki/%E6%B5%81%E8%A1%8C%E7%97%85%E5%AD%B8" title="流行病學 – Cantonese" lang="yue" hreflang="yue" data-title="流行病學" data-language-autonym="粵語" data-language-local-name="Cantonese" class="interlanguage-link-target"><span>粵語</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a 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a{color:var(--color-progressive)!important}}@media print{body.ns-0 .mw-parser-output .sidebar{display:none!important}}</style><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><table class="sidebar sidebar-collapse nomobile nowraplinks hlist"><tbody><tr><td class="sidebar-pretitle">Part of a <a href="/wiki/Category:Public_health" title="Category:Public health">series</a> on</td></tr><tr><th class="sidebar-title-with-pretitle"><a href="/wiki/Public_health" title="Public health">Public health</a></th></tr><tr><td class="sidebar-image"><span typeof="mw:File"><a href="/wiki/File:Community_Health_Advocate_-_The_Noun_Project.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Community_Health_Advocate_-_The_Noun_Project.svg/150px-Community_Health_Advocate_-_The_Noun_Project.svg.png" decoding="async" width="150" height="150" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Community_Health_Advocate_-_The_Noun_Project.svg/225px-Community_Health_Advocate_-_The_Noun_Project.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Community_Health_Advocate_-_The_Noun_Project.svg/300px-Community_Health_Advocate_-_The_Noun_Project.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></td></tr><tr><td class="sidebar-above" style="padding-bottom:0.35em;"> <div class="hlist"><ul><li><a href="/wiki/Outline_of_public_health" title="Outline of public health">Outline</a></li></ul></div></td></tr><tr><td class="sidebar-content" style="padding-top:0.2em;"> <div class="sidebar-list mw-collapsible mw-collapsed"><div class="sidebar-list-title" style="background:#ddddff;text-align:center;;color: var(--color-base)">Subfields</div><div class="sidebar-list-content mw-collapsible-content"> <ul><li><a href="/wiki/Community_health" title="Community health">Community health</a></li> <li><a href="/wiki/Dental_public_health" title="Dental public health">Dental public health</a></li> <li><a href="/wiki/Environmental_health" title="Environmental health">Environmental health</a></li> <li><a class="mw-selflink selflink">Epidemiology</a></li> <li><a href="/wiki/Health_economics" title="Health economics">Health economics</a></li> <li><a href="/wiki/Health_education" title="Health education">Health education</a></li> <li><a href="/wiki/Health_promotion" title="Health promotion">Health promotion</a></li> <li><a href="/wiki/Health_policy" title="Health policy">Health policy</a></li> <li><a href="/wiki/Health_politics" title="Health politics">Health politics</a></li> <li><a href="/wiki/Mental_health" title="Mental health">Mental health</a></li> <li><a href="/wiki/Occupational_safety_and_health" title="Occupational safety and health">Occupational safety</a></li> <li><a href="/wiki/Rehabilitation_(penology)" title="Rehabilitation (penology)">Rehabilitation (penology)</a></li> <li><a href="/wiki/Sexual_and_reproductive_health" title="Sexual and reproductive health">Sexual and reproductive health</a></li> <li><a href="/wiki/Sanitation" title="Sanitation">Sanitation</a></li> <li>World health (<a href="/wiki/Global_health" title="Global health">Global health</a> - <a href="/wiki/International_health" title="International health">International health</a>)</li></ul></div></div></td> </tr><tr><td class="sidebar-content" style="padding-top:0.2em;"> <div class="sidebar-list mw-collapsible mw-collapsed"><div class="sidebar-list-title" style="background:#ddddff;text-align:center;;color: var(--color-base)">Prevention</div><div class="sidebar-list-content mw-collapsible-content"> <ul><li><a href="/wiki/Disease_surveillance" title="Disease surveillance">Disease surveillance</a></li> <li><a href="/wiki/Harm_reduction" title="Harm reduction">Harm reduction</a></li> <li><a href="/wiki/Health_promotion" title="Health promotion">Health promotion</a> (<a href="/wiki/Behavior_change_(public_health)" title="Behavior change (public health)">Behavior change</a>)</li> <li><a href="/wiki/Health_indicators" class="mw-redirect" title="Health indicators">Health indicators</a></li> <li><a href="/wiki/Human_right_to_water_and_sanitation" title="Human right to water and sanitation">Human right to water and sanitation</a></li> <li><a href="/wiki/Right_to_health" title="Right to health">Right to health</a></li> <li><a href="/wiki/Supervised_injection_site" title="Supervised injection site">Supervised injection site</a></li> <li><a href="/wiki/Universal_health_care" title="Universal health care">Universal health care</a></li></ul></div></div></td> </tr><tr><td class="sidebar-content" style="padding-top:0.2em;"> <div class="sidebar-list mw-collapsible mw-collapsed"><div class="sidebar-list-title" style="background:#ddddff;text-align:center;;color: var(--color-base)"><a href="/wiki/Category:Public_health-related_lists" title="Category:Public health-related lists">Lists</a> and <a href="/wiki/Category:Public_health" title="Category:Public health">categories</a></div><div class="sidebar-list-content mw-collapsible-content"> <ul><li><a href="/wiki/Category:Public_health" title="Category:Public health">Terminology</a></li> <li><a href="/wiki/Category:Public_health_journals" title="Category:Public health journals">Journals</a></li> <li><a href="/wiki/List_of_national_public_health_agencies" title="List of national public health agencies">National public health agencies</a></li></ul></div></div></td> </tr><tr><td class="sidebar-below" style="border-top:1px solid #aaa;border-bottom:1px solid #aaa;"> <ul><li><span class="nowrap"><span class="noviewer" typeof="mw:File"><span><img alt="icon" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/WHO_Rod.svg/7px-WHO_Rod.svg.png" decoding="async" width="7" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/WHO_Rod.svg/10px-WHO_Rod.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d6/WHO_Rod.svg/13px-WHO_Rod.svg.png 2x" data-file-width="107" data-file-height="250" /></span></span> </span><a href="/wiki/Portal:Medicine" title="Portal:Medicine">Medicine portal</a></li> <li><span class="nowrap"><span class="noviewer" typeof="mw:File"><a href="/wiki/File:Social_sciences.svg" class="mw-file-description"><img alt="icon" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/42/Social_sciences.svg/16px-Social_sciences.svg.png" decoding="async" width="16" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/42/Social_sciences.svg/24px-Social_sciences.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/42/Social_sciences.svg/32px-Social_sciences.svg.png 2x" data-file-width="139" data-file-height="122" /></a></span> </span><a href="/wiki/Portal:Society" title="Portal:Society">Society portal</a></li></ul></td></tr><tr><td class="sidebar-navbar"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><style data-mw-deduplicate="TemplateStyles:r1239400231">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}html.skin-theme-clientpref-night .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Public_health_sidebar" title="Template:Public health sidebar"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Public_health_sidebar" title="Template talk:Public health sidebar"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Public_health_sidebar" title="Special:EditPage/Template:Public health sidebar"><abbr title="Edit this template">e</abbr></a></li></ul></div></td></tr></tbody></table> <p><b>Epidemiology</b> is the study and analysis of the distribution (who, when, and where), patterns and <a href="/wiki/Risk_factor_(epidemiology)" class="mw-redirect" title="Risk factor (epidemiology)">determinants</a> of health and disease conditions in a defined <a href="/wiki/Population" title="Population">population</a>, and application of this knowledge to prevent diseases. </p><p>It is a cornerstone of <a href="/wiki/Public_health" title="Public health">public health</a>, and shapes policy decisions and <a href="/wiki/Evidence-based_practice" title="Evidence-based practice">evidence-based practice</a> by identifying <a href="/wiki/Risk_factor_(epidemiology)" class="mw-redirect" title="Risk factor (epidemiology)">risk factors</a> for disease and targets for <a href="/wiki/Preventive_healthcare" title="Preventive healthcare">preventive healthcare</a>. Epidemiologists help with study design, collection, and <a href="/wiki/Statistical_analysis" class="mw-redirect" title="Statistical analysis">statistical analysis</a> of data, amend interpretation and dissemination of results (including <a href="/wiki/Peer_review" title="Peer review">peer review</a> and occasional <a href="/wiki/Systematic_review" title="Systematic review">systematic review</a>). Epidemiology has helped develop <a href="/wiki/Methodology" title="Methodology">methodology</a> used in <a href="/wiki/Clinical_research" title="Clinical research">clinical research</a>, <a href="/wiki/Public_health" title="Public health">public health</a> studies, and, to a lesser extent, <a href="/wiki/Basic_research" title="Basic research">basic research</a> in the biological sciences.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p><p>Major areas of epidemiological study include disease causation, <a href="/wiki/Transmission_(medicine)" class="mw-redirect" title="Transmission (medicine)">transmission</a>, <a href="/wiki/Outbreak" class="mw-redirect" title="Outbreak">outbreak</a> investigation, <a href="/wiki/Disease_surveillance" title="Disease surveillance">disease surveillance</a>, <a href="/wiki/Environmental_epidemiology" title="Environmental epidemiology">environmental epidemiology</a>, <a href="/wiki/Forensic_epidemiology" title="Forensic epidemiology">forensic epidemiology</a>, <a href="/wiki/Occupational_epidemiology" title="Occupational epidemiology">occupational epidemiology</a>, <a href="/wiki/Screening_(medicine)" title="Screening (medicine)">screening</a>, <a href="/wiki/Biomonitoring" title="Biomonitoring">biomonitoring</a>, and comparisons of treatment effects such as in <a href="/wiki/Clinical_trials" class="mw-redirect" title="Clinical trials">clinical trials</a>. Epidemiologists rely on other scientific disciplines like <a href="/wiki/Biology" title="Biology">biology</a> to better understand disease processes, <a href="/wiki/Statistics" title="Statistics">statistics</a> to make efficient use of the data and draw appropriate conclusions, <a href="/wiki/Social_science" title="Social science">social sciences</a> to better understand proximate and distal causes, and <a href="/wiki/Engineering" title="Engineering">engineering</a> for <a href="/wiki/Exposure_assessment" title="Exposure assessment">exposure assessment</a>. </p><p><i>Epidemiology</i>, literally meaning "the study of what is upon the people", is derived from <a href="/wiki/Greek_language" title="Greek language">Greek</a> <i> epi</i> 'upon, among' <i> <a href="/wiki/Glossary_of_rhetorical_terms#Demos" title="Glossary of rhetorical terms">demos</a></i> 'people, district' and <i> <a href="/wiki/Logos" title="Logos">logos</a></i> 'study, word, discourse', suggesting that it applies only to human populations. However, the term is widely used in studies of zoological populations (veterinary epidemiology), although the term "<a href="/wiki/Epizoology" class="mw-redirect" title="Epizoology">epizoology</a>" is available, and it has also been applied to studies of plant populations (botanical or <a href="/wiki/Plant_disease_epidemiology" title="Plant disease epidemiology">plant disease epidemiology</a>).<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p><p>The distinction between "epidemic" and "endemic" was first drawn by <a href="/wiki/Hippocrates" title="Hippocrates">Hippocrates</a>,<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> to distinguish between diseases that are "visited upon" a population (epidemic) from those that "reside within" a population (endemic).<sup id="cite_ref-Carol_Buck_1998_p3_4-0" class="reference"><a href="#cite_note-Carol_Buck_1998_p3-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> The term "epidemiology" appears to have first been used to describe the study of epidemics in 1802 by the Spanish physician <a href="/w/index.php?title=Joaqu%C3%ADn_de_Villalba&action=edit&redlink=1" class="new" title="Joaquín de Villalba (page does not exist)">Joaquín de Villalba</a><span class="noprint" style="font-size:85%; font-style: normal;"> [<a href="https://es.wikipedia.org/wiki/Joaqu%C3%ADn_de_Villalba" class="extiw" title="es:Joaquín de Villalba">es</a>]</span> in <i>Epidemiología Española</i>.<sup id="cite_ref-Carol_Buck_1998_p3_4-1" class="reference"><a href="#cite_note-Carol_Buck_1998_p3-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> Epidemiologists also study the interaction of diseases in a population, a condition known as a <a href="/wiki/Syndemic" title="Syndemic">syndemic</a>. </p><p>The term epidemiology is now widely applied to cover the description and causation of not only epidemic, infectious disease, but of disease in general, including related conditions. Some examples of topics examined through epidemiology include as high blood pressure, mental illness and <a href="/wiki/Obesity" title="Obesity">obesity</a>. Therefore, this epidemiology is based upon how the pattern of the disease causes change in the function of human beings. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="History">History</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=1" title="Edit section: History"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The Greek physician <a href="/wiki/Hippocrates" title="Hippocrates">Hippocrates</a>, taught by Democritus, was known as the father of <a href="/wiki/Medicine" title="Medicine">medicine</a>,<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> sought a logic to sickness; he is the first person known to have examined the relationships between the occurrence of disease and environmental influences.<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> Hippocrates believed sickness of the human body to be caused by an imbalance of the four <a href="/wiki/Humorism" title="Humorism">humors</a> (black bile, yellow bile, blood, and phlegm). The cure to the sickness was to remove or add the humor in question to balance the body. This belief led to the application of bloodletting and dieting in medicine.<sup id="cite_ref-Merril,_Ray_M._2010_8-0" class="reference"><a href="#cite_note-Merril,_Ray_M._2010-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> He coined the terms <a href="/wiki/Endemic_(epidemiology)" title="Endemic (epidemiology)"><i>endemic</i></a> (for diseases usually found in some places but not in others) and <i><a href="/wiki/Epidemic" title="Epidemic">epidemic</a></i> (for diseases that are seen at some times but not others).<sup id="cite_ref-hip_9-0" class="reference"><a href="#cite_note-hip-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Modern_era">Modern era</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=2" title="Edit section: Modern era"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">See also: <a href="/wiki/History_of_emerging_infectious_diseases" class="mw-redirect" title="History of emerging infectious diseases">History of emerging infectious diseases</a></div> <p>In the middle of the 16th century, a doctor from <a href="/wiki/Verona" title="Verona">Verona</a> named <a href="/wiki/Girolamo_Fracastoro" title="Girolamo Fracastoro">Girolamo Fracastoro</a> was the first to propose a theory that the very small, unseeable, particles that cause disease were alive. They were considered to be able to spread by air, multiply by themselves and to be destroyable by fire. In this way he refuted <a href="/wiki/Galen" title="Galen">Galen</a>'s <a href="/wiki/Miasma_theory_of_disease" class="mw-redirect" title="Miasma theory of disease">miasma theory</a> (poison gas in sick people). In 1543 he wrote a book <i><a href="/wiki/De_contagione_et_contagiosis_morbis" class="mw-redirect" title="De contagione et contagiosis morbis">De contagione et contagiosis morbis</a></i>, in which he was the first to promote personal and environmental <a href="/wiki/Hygiene" title="Hygiene">hygiene</a> to prevent disease. The development of a sufficiently powerful microscope by <a href="/wiki/Antonie_van_Leeuwenhoek" title="Antonie van Leeuwenhoek">Antonie van Leeuwenhoek</a> in 1675 provided visual evidence of living particles consistent with a <a href="/wiki/Germ_theory_of_disease" title="Germ theory of disease">germ theory of disease</a>.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (June 2022)">citation needed</span></a></i>]</sup> </p><p>During the <a href="/wiki/Ming_dynasty" title="Ming dynasty">Ming dynasty</a>, <a href="/w/index.php?title=Wu_Youke&action=edit&redlink=1" class="new" title="Wu Youke (page does not exist)">Wu Youke</a> (1582–1652) developed the idea that some diseases were caused by transmissible agents, which he called <i>Li Qi</i> (戾气 or pestilential factors) when he observed various epidemics rage around him between 1641 and 1644.<sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> His book <i>Wen Yi Lun</i> (瘟疫论, Treatise on Pestilence/Treatise of Epidemic Diseases) can be regarded as the main etiological work that brought forward the concept.<sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> His concepts were still being considered in analysing SARS outbreak by WHO in 2004 in the context of traditional Chinese medicine.<sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> </p><p>Another pioneer, <a href="/wiki/Thomas_Sydenham" title="Thomas Sydenham">Thomas Sydenham</a> (1624–1689), was the first to distinguish the fevers of Londoners in the later 1600s. His theories on cures of fevers met with much resistance from traditional physicians at the time. He was not able to find the initial cause of the <a href="/wiki/Smallpox" title="Smallpox">smallpox</a> fever he researched and treated.<sup id="cite_ref-Merril,_Ray_M._2010_8-1" class="reference"><a href="#cite_note-Merril,_Ray_M._2010-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> </p><p><a href="/wiki/John_Graunt" title="John Graunt">John Graunt</a>, a <a href="/wiki/Haberdasher" title="Haberdasher">haberdasher</a> and amateur statistician, published <i>Natural and Political Observations ... upon the Bills of Mortality</i> in 1662. In it, he analysed the mortality rolls in <a href="/wiki/London" title="London">London</a> before the <a href="/wiki/Great_Plague_of_London" title="Great Plague of London">Great Plague</a>, presented one of the first <a href="/wiki/Life_tables" class="mw-redirect" title="Life tables">life tables</a>, and reported time trends for many diseases, new and old. He provided statistical evidence for many theories on disease, and also refuted some widespread ideas on them.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (June 2022)">citation needed</span></a></i>]</sup> </p> <figure typeof="mw:File/Thumb"><a href="/wiki/File:Snow-cholera-map.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/c/c7/Snow-cholera-map.jpg/350px-Snow-cholera-map.jpg" decoding="async" width="350" height="342" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/c7/Snow-cholera-map.jpg/525px-Snow-cholera-map.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/c7/Snow-cholera-map.jpg/700px-Snow-cholera-map.jpg 2x" data-file-width="889" data-file-height="869" /></a><figcaption>Original map by <a href="/wiki/John_Snow_(physician)" class="mw-redirect" title="John Snow (physician)">John Snow</a> showing the <a href="/wiki/Cluster_(epidemiology)" class="mw-redirect" title="Cluster (epidemiology)">clusters</a> of cholera cases in the <a href="/wiki/1854_Broad_Street_cholera_outbreak" title="1854 Broad Street cholera outbreak">London epidemic of 1854</a></figcaption></figure> <p><a href="/wiki/John_Snow_(physician)" class="mw-redirect" title="John Snow (physician)">John Snow</a> is famous for his investigations into the causes of the 19th-century <a href="/wiki/Cholera" title="Cholera">cholera</a> epidemics, and is also known as the father of (modern) Epidemiology.<sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-14" class="reference"><a href="#cite_note-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> He began with noticing the significantly higher death rates in two areas supplied by Southwark Company. His identification of the <a href="/wiki/Broadwick_Street" title="Broadwick Street">Broad Street</a> pump as the cause of the Soho epidemic is considered the classic example of epidemiology. Snow used chlorine in an attempt to clean the water and removed the handle; this ended the outbreak. This has been perceived as a major event in the history of <a href="/wiki/Public_health" title="Public health">public health</a> and regarded as the founding event of the science of epidemiology, having helped shape public health policies around the world.<sup id="cite_ref-15" class="reference"><a href="#cite_note-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-16" class="reference"><a href="#cite_note-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup> However, Snow's research and preventive measures to avoid further outbreaks were not fully accepted or put into practice until after his death due to the prevailing <a href="/wiki/Miasma_theory" title="Miasma theory">Miasma Theory</a> of the time, a model of disease in which poor air quality was blamed for illness. This was used to rationalize high rates of infection in impoverished areas instead of addressing the underlying issues of poor nutrition and sanitation, and was proven false by his work.<sup id="cite_ref-17" class="reference"><a href="#cite_note-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> </p><p>Other pioneers include Danish physician <a href="/w/index.php?title=Peter_Anton_Schleisner&action=edit&redlink=1" class="new" title="Peter Anton Schleisner (page does not exist)">Peter Anton Schleisner</a>, who in 1849 related his work on the prevention of the epidemic of <a href="/wiki/Neonatal_tetanus" title="Neonatal tetanus">neonatal tetanus</a> on the <a href="/wiki/Vestmanna_Islands" class="mw-redirect" title="Vestmanna Islands">Vestmanna Islands</a> in <a href="/wiki/Iceland" title="Iceland">Iceland</a>.<sup id="cite_ref-18" class="reference"><a href="#cite_note-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-19" class="reference"><a href="#cite_note-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> Another important pioneer was <a href="/wiki/Hungary" title="Hungary">Hungarian</a> physician <a href="/wiki/Ignaz_Semmelweis" title="Ignaz Semmelweis">Ignaz Semmelweis</a>, who in 1847 brought down infant mortality at a Vienna hospital by instituting a disinfection procedure. His findings were published in 1850, but his work was ill-received by his colleagues, who discontinued the procedure. Disinfection did not become widely practiced until British surgeon <a href="/wiki/Joseph_Lister,_1st_Baron_Lister" class="mw-redirect" title="Joseph Lister, 1st Baron Lister">Joseph Lister</a> 'discovered' <a href="/wiki/Antiseptics" class="mw-redirect" title="Antiseptics">antiseptics</a> in 1865 in light of the work of <a href="/wiki/Louis_Pasteur" title="Louis Pasteur">Louis Pasteur</a>.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (June 2022)">citation needed</span></a></i>]</sup> </p><p>In the early 20th century, mathematical methods were introduced into epidemiology by <a href="/wiki/Ronald_Ross" title="Ronald Ross">Ronald Ross</a>, <a href="/wiki/Janet_Lane-Claypon" title="Janet Lane-Claypon">Janet Lane-Claypon</a>, <a href="/wiki/Anderson_Gray_McKendrick" title="Anderson Gray McKendrick">Anderson Gray McKendrick</a>, and others.<sup id="cite_ref-20" class="reference"><a href="#cite_note-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-21" class="reference"><a href="#cite_note-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-22" class="reference"><a href="#cite_note-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-23" class="reference"><a href="#cite_note-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup> In a parallel development during the 1920s, German-Swiss pathologist <a href="/wiki/Max_Askanazy" title="Max Askanazy">Max Askanazy</a> and others founded the International Society for Geographical Pathology to systematically investigate the geographical pathology of cancer and other non-infectious diseases across populations in different regions. After World War II, <a href="/wiki/Richard_Doll" title="Richard Doll">Richard Doll</a> and other non-pathologists joined the field and advanced methods to study cancer, a disease with patterns and mode of occurrences that could not be suitably studied with the methods developed for epidemics of infectious diseases. Geography pathology eventually combined with infectious disease epidemiology to make the field that is epidemiology today.<sup id="cite_ref-cancer_24-0" class="reference"><a href="#cite_note-cancer-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup> </p><p>Another breakthrough was the 1954 publication of the results of a <a href="/wiki/British_Doctors_Study" title="British Doctors Study">British Doctors Study</a>, led by <a href="/wiki/Richard_Doll" title="Richard Doll">Richard Doll</a> and <a href="/wiki/Austin_Bradford_Hill" title="Austin Bradford Hill">Austin Bradford Hill</a>, which lent very strong statistical support to the link between <a href="/wiki/Tobacco_smoking" title="Tobacco smoking">tobacco smoking</a> and <a href="/wiki/Lung_cancer" title="Lung cancer">lung cancer</a>.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (November 2023)">citation needed</span></a></i>]</sup> </p><p>In the late 20th century, with the advancement of biomedical sciences, a number of molecular markers in blood, other biospecimens and environment were identified as predictors of development or risk of a certain disease. Epidemiology research to examine the relationship between these <a href="/wiki/Biomarker" title="Biomarker">biomarkers</a> analyzed at the molecular level and disease was broadly named "<a href="/wiki/Molecular_epidemiology" title="Molecular epidemiology">molecular epidemiology</a>". Specifically, "<a href="/wiki/Genetic_epidemiology" title="Genetic epidemiology">genetic epidemiology</a>" has been used for epidemiology of germline genetic variation and disease. Genetic variation is typically determined using DNA from peripheral blood leukocytes.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (June 2022)">citation needed</span></a></i>]</sup> </p> <div class="mw-heading mw-heading3"><h3 id="21st_century">21st century</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=3" title="Edit section: 21st century"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Since the 2000s, <a href="/wiki/Genome-wide_association_study" title="Genome-wide association study">genome-wide association studies</a> (GWAS) have been commonly performed to identify genetic risk factors for many diseases and health conditions.<sup id="cite_ref-25" class="reference"><a href="#cite_note-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup> </p><p>While most molecular epidemiology studies are still using conventional disease <a href="/wiki/Diagnosis" title="Diagnosis">diagnosis</a> and classification systems, it is increasingly recognized that disease progression represents inherently heterogeneous processes differing from person to person. Conceptually, each individual has a unique disease process different from any other individual ("the unique disease principle"),<sup id="cite_ref-26" class="reference"><a href="#cite_note-26"><span class="cite-bracket">[</span>26<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-27" class="reference"><a href="#cite_note-27"><span class="cite-bracket">[</span>27<span class="cite-bracket">]</span></a></sup> considering uniqueness of the <a href="/wiki/Exposome" title="Exposome">exposome</a> (a totality of endogenous and exogenous / environmental exposures) and its unique influence on molecular pathologic process in each individual. Studies to examine the relationship between an exposure and molecular pathologic signature of disease (particularly <a href="/wiki/Cancer" title="Cancer">cancer</a>) became increasingly common throughout the 2000s. However, the use of <a href="/wiki/Molecular_pathology" title="Molecular pathology">molecular pathology</a> in epidemiology posed unique challenges, including lack of research guidelines and standardized <a href="/wiki/Statistics" title="Statistics">statistical</a> methodologies, and paucity of interdisciplinary experts and training programs.<sup id="cite_ref-28" class="reference"><a href="#cite_note-28"><span class="cite-bracket">[</span>28<span class="cite-bracket">]</span></a></sup> Furthermore, the concept of disease heterogeneity appears to conflict with the long-standing premise in epidemiology that individuals with the same disease name have similar etiologies and disease processes. To resolve these issues and advance population health science in the era of molecular <a href="/wiki/Precision_medicine" class="mw-redirect" title="Precision medicine">precision medicine</a>, "molecular pathology" and "epidemiology" was integrated to create a new interdisciplinary field of "<a href="/wiki/Molecular_pathological_epidemiology" title="Molecular pathological epidemiology">molecular pathological epidemiology</a>" (MPE),<sup id="cite_ref-29" class="reference"><a href="#cite_note-29"><span class="cite-bracket">[</span>29<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-30" class="reference"><a href="#cite_note-30"><span class="cite-bracket">[</span>30<span class="cite-bracket">]</span></a></sup> defined as "epidemiology of molecular pathology and heterogeneity of disease". In MPE, investigators analyze the relationships between (A) environmental, dietary, lifestyle and genetic factors; (B) alterations in cellular or extracellular molecules; and (C) evolution and progression of disease. A better understanding of heterogeneity of disease <a href="/wiki/Pathogenesis" title="Pathogenesis">pathogenesis</a> will further contribute to elucidate <a href="/wiki/Etiology" title="Etiology">etiologies</a> of disease. The MPE approach can be applied to not only neoplastic diseases but also non-neoplastic diseases.<sup id="cite_ref-31" class="reference"><a href="#cite_note-31"><span class="cite-bracket">[</span>31<span class="cite-bracket">]</span></a></sup> The concept and paradigm of MPE have become widespread in the 2010s.<sup id="cite_ref-32" class="reference"><a href="#cite_note-32"><span class="cite-bracket">[</span>32<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-33" class="reference"><a href="#cite_note-33"><span class="cite-bracket">[</span>33<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-34" class="reference"><a href="#cite_note-34"><span class="cite-bracket">[</span>34<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-35" class="reference"><a href="#cite_note-35"><span class="cite-bracket">[</span>35<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-36" class="reference"><a href="#cite_note-36"><span class="cite-bracket">[</span>36<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-37" class="reference"><a href="#cite_note-37"><span class="cite-bracket">[</span>37<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-38" class="reference"><a href="#cite_note-38"><span class="cite-bracket">[</span>38<span class="cite-bracket">]</span></a></sup><sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citing_sources#Bundling_citations" title="Wikipedia:Citing sources"><span title="This claim has too many footnotes for reading to be smooth. (March 2023)">excessive citations</span></a></i>]</sup> </p><p>By 2012, it was recognized that many pathogens' <a href="/wiki/Evolution" title="Evolution">evolution</a> is rapid enough to be highly relevant to epidemiology, and that therefore much could be gained from an interdisciplinary approach to infectious disease integrating epidemiology and <a href="/wiki/Molecular_evolution" title="Molecular evolution">molecular evolution</a> to "inform control strategies, or even patient treatment."<sup id="cite_ref-39" class="reference"><a href="#cite_note-39"><span class="cite-bracket">[</span>39<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-40" class="reference"><a href="#cite_note-40"><span class="cite-bracket">[</span>40<span class="cite-bracket">]</span></a></sup> Modern epidemiological studies can use advanced statistics and <a href="/wiki/Machine_learning" title="Machine learning">machine learning</a> to create <a href="/wiki/Predictive_modelling" title="Predictive modelling">predictive models</a> as well as to define treatment effects.<sup id="cite_ref-41" class="reference"><a href="#cite_note-41"><span class="cite-bracket">[</span>41<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-42" class="reference"><a href="#cite_note-42"><span class="cite-bracket">[</span>42<span class="cite-bracket">]</span></a></sup> There is increasing recognition that a wide range of modern data sources, many not originating from healthcare or epidemiology, can be used for epidemiological study. Such digital epidemiology can include data from internet searching, mobile phone records and retail sales of drugs.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (November 2023)">citation needed</span></a></i>]</sup> </p> <div class="mw-heading mw-heading2"><h2 id="Types_of_studies">Types of studies</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=4" title="Edit section: Types of studies"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/File:Epidemiologic_study_hierarchy.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/05/Epidemiologic_study_hierarchy.png/220px-Epidemiologic_study_hierarchy.png" decoding="async" width="220" height="199" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/05/Epidemiologic_study_hierarchy.png/330px-Epidemiologic_study_hierarchy.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/05/Epidemiologic_study_hierarchy.png/440px-Epidemiologic_study_hierarchy.png 2x" data-file-width="625" data-file-height="564" /></a><figcaption>Epidemiologic study hierarchy</figcaption></figure> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Study_design" class="mw-redirect" title="Study design">Study design</a></div> <p>Epidemiologists employ a range of study designs from the observational to experimental and generally categorized as descriptive (involving the assessment of data covering time, place, and person), analytic (aiming to further examine known associations or hypothesized relationships), and experimental (a term often equated with clinical or community trials of treatments and other interventions). In observational studies, nature is allowed to "take its course", as epidemiologists observe from the sidelines. Conversely, in experimental studies, the epidemiologist is the one in control of all of the factors entering a certain case study.<sup id="cite_ref-Epidemiology_2009_43-0" class="reference"><a href="#cite_note-Epidemiology_2009-43"><span class="cite-bracket">[</span>43<span class="cite-bracket">]</span></a></sup> Epidemiological studies are aimed, where possible, at revealing unbiased relationships between <a href="/wiki/Exposure_Assessment#Exposure" class="mw-redirect" title="Exposure Assessment">exposures</a> such as alcohol or smoking, <a href="/wiki/Infections" class="mw-redirect" title="Infections">biological agents</a>, <a href="/wiki/Stress_(medicine)" class="mw-redirect" title="Stress (medicine)">stress</a>, or <a href="/wiki/Chemical_compound" title="Chemical compound">chemicals</a> to <a href="/wiki/Death" title="Death">mortality</a> or <a href="/wiki/Morbidity" class="mw-redirect" title="Morbidity">morbidity</a>. The identification of causal relationships between these exposures and outcomes is an important aspect of epidemiology. Modern epidemiologists use <a href="/wiki/Health_informatics" title="Health informatics">informatics</a> and <a href="/wiki/Infodemiology" title="Infodemiology">infodemiology</a><sup id="cite_ref-44" class="reference"><a href="#cite_note-44"><span class="cite-bracket">[</span>44<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-45" class="reference"><a href="#cite_note-45"><span class="cite-bracket">[</span>45<span class="cite-bracket">]</span></a></sup> as tools.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (June 2022)">citation needed</span></a></i>]</sup><sup id="cite_ref-46" class="reference"><a href="#cite_note-46"><span class="cite-bracket">[</span>46<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-47" class="reference"><a href="#cite_note-47"><span class="cite-bracket">[</span>47<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-48" class="reference"><a href="#cite_note-48"><span class="cite-bracket">[</span>48<span class="cite-bracket">]</span></a></sup> </p><p>Observational studies have two components, descriptive and analytical. Descriptive observations pertain to the "who, what, where and when of health-related state occurrence". However, analytical observations deal more with the 'how' of a health-related event.<sup id="cite_ref-Epidemiology_2009_43-1" class="reference"><a href="#cite_note-Epidemiology_2009-43"><span class="cite-bracket">[</span>43<span class="cite-bracket">]</span></a></sup> <a href="/w/index.php?title=Experimental_epidemiology&action=edit&redlink=1" class="new" title="Experimental epidemiology (page does not exist)">Experimental epidemiology</a> contains three case types: randomized controlled trials (often used for a new medicine or drug testing), field trials (conducted on those at a high risk of contracting a disease), and community trials (research on social originating diseases).<sup id="cite_ref-Epidemiology_2009_43-2" class="reference"><a href="#cite_note-Epidemiology_2009-43"><span class="cite-bracket">[</span>43<span class="cite-bracket">]</span></a></sup> </p><p>The term 'epidemiologic triad' is used to describe the intersection of <i>Host</i>, <i>Agent</i>, and <i>Environment</i> in analyzing an outbreak.<sup id="cite_ref-49" class="reference"><a href="#cite_note-49"><span class="cite-bracket">[</span>49<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Case_series">Case series</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=5" title="Edit section: Case series"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Case-series may refer to the qualitative study of the experience of a single patient, or small group of patients with a similar diagnosis, or to a statistical factor with the potential to produce illness with periods when they are unexposed.<sup id="cite_ref-50" class="reference"><a href="#cite_note-50"><span class="cite-bracket">[</span>50<span class="cite-bracket">]</span></a></sup> </p><p>The former type of study is purely descriptive and cannot be used to make inferences about the general population of patients with that disease. These types of studies, in which an astute clinician identifies an unusual feature of a disease or a patient's history, may lead to a formulation of a new hypothesis. Using the data from the series, analytic studies could be done to investigate possible causal factors. These can include case-control studies or prospective studies. A case-control study would involve matching comparable controls without the disease to the cases in the series. A prospective study would involve following the case series over time to evaluate the disease's natural history.<sup id="cite_ref-51" class="reference"><a href="#cite_note-51"><span class="cite-bracket">[</span>51<span class="cite-bracket">]</span></a></sup> </p><p>The latter type, more formally described as <a href="/w/index.php?title=Self-controlled_case-series&action=edit&redlink=1" class="new" title="Self-controlled case-series (page does not exist)">self-controlled case-series</a> studies, divide individual patient follow-up time into exposed and unexposed periods and use fixed-effects Poisson regression processes to compare the incidence rate of a given outcome between exposed and unexposed periods. This technique has been extensively used in the study of adverse reactions to vaccination and has been shown in some circumstances to provide statistical power comparable to that available in cohort studies.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (June 2022)">citation needed</span></a></i>]</sup> </p> <div class="mw-heading mw-heading3"><h3 id="Case-control_studies">Case-control studies</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=6" title="Edit section: Case-control studies"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Case-control_study" class="mw-redirect" title="Case-control study">Case-control studies</a> select subjects based on their disease status. It is a retrospective study. A group of individuals that are disease positive (the "case" group) is compared with a group of disease negative individuals (the "control" group). The control group should ideally come from the same population that gave rise to the cases. The case-control study looks back through time at potential exposures that both groups (cases and controls) may have encountered. A 2×2 table is constructed, displaying exposed cases (A), exposed controls (B), unexposed cases (C) and unexposed controls (D). The statistic generated to measure association is the <a href="/wiki/Odds_ratio" title="Odds ratio">odds ratio</a> (OR),<sup id="cite_ref-52" class="reference"><a href="#cite_note-52"><span class="cite-bracket">[</span>52<span class="cite-bracket">]</span></a></sup> which is the ratio of the odds of exposure in the cases (A/C) to the odds of exposure in the controls (B/D), i.e. OR = (AD/BC).<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (March 2023)">citation needed</span></a></i>]</sup> </p> <table class="wikitable"> <tbody><tr> <th> </th> <th>Cases </th> <th>Controls </th></tr> <tr> <td>Exposed </td> <td>A </td> <td>B </td></tr> <tr> <td>Unexposed </td> <td>C </td> <td>D </td></tr></tbody></table> <p>If the OR is significantly greater than 1, then the conclusion is "those with the disease are more likely to have been exposed", whereas if it is close to 1 then the exposure and disease are not likely associated. If the OR is far less than one, then this suggests that the exposure is a protective factor in the causation of the disease. Case-control studies are usually faster and more cost-effective than <a href="/wiki/Cohort_studies" class="mw-redirect" title="Cohort studies">cohort studies</a> but are sensitive to bias (such as <a href="/wiki/Recall_bias" title="Recall bias">recall bias</a> and <a href="/wiki/Selection_bias" title="Selection bias">selection bias</a>). The main challenge is to identify the appropriate control group; the distribution of exposure among the control group should be representative of the distribution in the population that gave rise to the cases. This can be achieved by drawing a random sample from the original population at risk. This has as a consequence that the control group can contain people with the disease under study when the disease has a high attack rate in a population.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (March 2023)">citation needed</span></a></i>]</sup> </p><p>A major drawback for case control studies is that, in order to be considered to be statistically significant, the minimum number of cases required at the 95% confidence interval is related to the odds ratio by the equation: </p> <dl><dd><span class="mwe-math-element"><span class="mwe-math-mathml-inline mwe-math-mathml-a11y" style="display: none;"><math xmlns="http://www.w3.org/1998/Math/MathML" alttext="{\displaystyle {\text{total cases}}=A+C=1.96^{2}(1+N)\left({\frac {1}{\ln(OR)}}\right)^{2}\left({\frac {OR+2{\sqrt {OR}}+1}{\sqrt {OR}}}\right)\approx 15.5(1+N)\left({\frac {1}{\ln(OR)}}\right)^{2}}"> <semantics> <mrow class="MJX-TeXAtom-ORD"> <mstyle displaystyle="true" scriptlevel="0"> <mrow class="MJX-TeXAtom-ORD"> <mtext>total cases</mtext> </mrow> <mo>=</mo> <mi>A</mi> <mo>+</mo> <mi>C</mi> <mo>=</mo> <msup> <mn>1.96</mn> <mrow class="MJX-TeXAtom-ORD"> <mn>2</mn> </mrow> </msup> <mo stretchy="false">(</mo> <mn>1</mn> <mo>+</mo> <mi>N</mi> <mo stretchy="false">)</mo> <msup> <mrow> <mo>(</mo> <mrow class="MJX-TeXAtom-ORD"> <mfrac> <mn>1</mn> <mrow> <mi>ln</mi> <mo>⁡</mo> <mo stretchy="false">(</mo> <mi>O</mi> <mi>R</mi> <mo stretchy="false">)</mo> </mrow> </mfrac> </mrow> <mo>)</mo> </mrow> <mrow class="MJX-TeXAtom-ORD"> <mn>2</mn> </mrow> </msup> <mrow> <mo>(</mo> <mrow class="MJX-TeXAtom-ORD"> <mfrac> <mrow> <mi>O</mi> <mi>R</mi> <mo>+</mo> <mn>2</mn> <mrow class="MJX-TeXAtom-ORD"> <msqrt> <mi>O</mi> <mi>R</mi> </msqrt> </mrow> <mo>+</mo> <mn>1</mn> </mrow> <msqrt> <mi>O</mi> <mi>R</mi> </msqrt> </mfrac> </mrow> <mo>)</mo> </mrow> <mo>≈</mo> <mn>15.5</mn> <mo stretchy="false">(</mo> <mn>1</mn> <mo>+</mo> <mi>N</mi> <mo stretchy="false">)</mo> <msup> <mrow> <mo>(</mo> <mrow class="MJX-TeXAtom-ORD"> <mfrac> <mn>1</mn> <mrow> <mi>ln</mi> <mo>⁡</mo> <mo stretchy="false">(</mo> <mi>O</mi> <mi>R</mi> <mo stretchy="false">)</mo> </mrow> </mfrac> </mrow> <mo>)</mo> </mrow> <mrow class="MJX-TeXAtom-ORD"> <mn>2</mn> </mrow> </msup> </mstyle> </mrow> <annotation encoding="application/x-tex">{\displaystyle {\text{total cases}}=A+C=1.96^{2}(1+N)\left({\frac {1}{\ln(OR)}}\right)^{2}\left({\frac {OR+2{\sqrt {OR}}+1}{\sqrt {OR}}}\right)\approx 15.5(1+N)\left({\frac {1}{\ln(OR)}}\right)^{2}}</annotation> </semantics> </math></span><img src="https://wikimedia.org/api/rest_v1/media/math/render/svg/dd6169f7c8b9da7c336370942c33fa820e5f57f2" class="mwe-math-fallback-image-inline mw-invert skin-invert" aria-hidden="true" style="vertical-align: -2.838ex; width:97.996ex; height:6.843ex;" alt="{\displaystyle {\text{total cases}}=A+C=1.96^{2}(1+N)\left({\frac {1}{\ln(OR)}}\right)^{2}\left({\frac {OR+2{\sqrt {OR}}+1}{\sqrt {OR}}}\right)\approx 15.5(1+N)\left({\frac {1}{\ln(OR)}}\right)^{2}}"></span></dd></dl> <p>where N is the ratio of cases to controls. As the odds ratio approaches 1, the number of cases required for statistical significance grows towards infinity; rendering case-control studies all but useless for low odds ratios. For instance, for an odds ratio of 1.5 and cases = controls, the table shown above would look like this: </p> <table class="wikitable"> <tbody><tr> <th> </th> <th>Cases </th> <th>Controls </th></tr> <tr> <td>Exposed </td> <td>103 </td> <td>84 </td></tr> <tr> <td>Unexposed </td> <td>84 </td> <td>103 </td></tr></tbody></table> <p>For an odds ratio of 1.1: </p> <table class="wikitable"> <tbody><tr> <th> </th> <th>Cases </th> <th>Controls </th></tr> <tr> <td>Exposed </td> <td>1732 </td> <td>1652 </td></tr> <tr> <td>Unexposed </td> <td>1652 </td> <td>1732 </td></tr></tbody></table> <div class="mw-heading mw-heading3"><h3 id="Cohort_studies">Cohort studies</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=7" title="Edit section: Cohort studies"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Cohort_studies" class="mw-redirect" title="Cohort studies">Cohort studies</a> select subjects based on their exposure status. The study subjects should be at risk of the outcome under investigation at the beginning of the cohort study; this usually means that they should be disease free when the cohort study starts. The cohort is followed through time to assess their later outcome status. An example of a cohort study would be the investigation of a cohort of smokers and non-smokers over time to estimate the incidence of lung cancer. The same 2×2 table is constructed as with the case control study. However, the point estimate generated is the <a href="/wiki/Relative_risk" title="Relative risk">relative risk</a> (RR), which is the probability of disease for a person in the exposed group, <i>P</i><sub>e</sub> = <i>A</i> / (<i>A</i> + <i>B</i>) over the probability of disease for a person in the unexposed group, <i>P</i><sub><i>u</i></sub> = <i>C</i> / (<i>C</i> + <i>D</i>), i.e. <i>RR</i> = <i>P</i><sub>e</sub> / <i>P</i><sub>u</sub>. </p> <table class="wikitable"> <tbody><tr> <th>..... </th> <th>Case </th> <th>Non-case </th> <th>Total </th></tr> <tr> <td>Exposed </td> <td><i>A</i> </td> <td><i>B</i> </td> <td>(<i>A</i> + <i>B</i>) </td></tr> <tr> <td>Unexposed </td> <td><i>C</i> </td> <td><i>D</i> </td> <td>(<i>C</i> + <i>D</i>) </td></tr></tbody></table> <p>As with the OR, a RR greater than 1 shows association, where the conclusion can be read "those with the exposure were more likely to develop the disease." </p><p>Prospective studies have many benefits over case control studies. The RR is a more powerful effect measure than the OR, as the OR is just an estimation of the RR, since true incidence cannot be calculated in a case control study where subjects are selected based on disease status. Temporality can be established in a prospective study, and confounders are more easily controlled for. However, they are more costly, and there is a greater chance of losing subjects to follow-up based on the long time period over which the cohort is followed. </p><p>Cohort studies also are limited by the same equation for number of cases as for cohort studies, but, if the base incidence rate in the study population is very low, the number of cases required is reduced by <style data-mw-deduplicate="TemplateStyles:r1154941027">.mw-parser-output .frac{white-space:nowrap}.mw-parser-output .frac .num,.mw-parser-output .frac .den{font-size:80%;line-height:0;vertical-align:super}.mw-parser-output .frac .den{vertical-align:sub}.mw-parser-output .sr-only{border:0;clip:rect(0,0,0,0);clip-path:polygon(0px 0px,0px 0px,0px 0px);height:1px;margin:-1px;overflow:hidden;padding:0;position:absolute;width:1px}</style><span class="frac"><span class="num">1</span>⁄<span class="den">2</span></span>. </p> <div class="mw-heading mw-heading2"><h2 id="Causal_inference">Causal inference</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=8" title="Edit section: Causal inference"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Causal_inference" title="Causal inference">Causal inference</a></div> <p>Although epidemiology is sometimes viewed as a collection of statistical tools used to elucidate the associations of exposures to health outcomes, a deeper understanding of this science is that of discovering <i>causal</i> relationships. </p><p>"<a href="/wiki/Correlation_does_not_imply_causation" title="Correlation does not imply causation">Correlation does not imply causation</a>" is a common theme for much of the epidemiological literature. For epidemiologists, the key is in the term <a href="/wiki/Inference" title="Inference">inference</a>. Correlation, or at least association between two variables, is a necessary but not sufficient criterion for the inference that one variable causes the other. Epidemiologists use gathered data and a broad range of biomedical and psychosocial theories in an iterative way to generate or expand theory, to test hypotheses, and to make educated, informed assertions about which relationships are causal, and about exactly how they are causal. </p><p>Epidemiologists emphasize that the "<b>one cause – one effect</b>" understanding is a simplistic mis-belief.<sup id="cite_ref-53" class="reference"><a href="#cite_note-53"><span class="cite-bracket">[</span>53<span class="cite-bracket">]</span></a></sup> Most outcomes, whether disease or death, are caused by a chain or web consisting of many component causes.<sup id="cite_ref-54" class="reference"><a href="#cite_note-54"><span class="cite-bracket">[</span>54<span class="cite-bracket">]</span></a></sup> Causes can be distinguished as necessary, sufficient or probabilistic conditions. If a necessary condition can be identified and controlled (e.g., antibodies to a disease agent, energy in an injury), the harmful outcome can be avoided (Robertson, 2015). One tool regularly used to conceptualize the multicausality associated with disease is the <a href="/wiki/Causal_pie_model" title="Causal pie model">causal pie model</a>.<sup id="cite_ref-55" class="reference"><a href="#cite_note-55"><span class="cite-bracket">[</span>55<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Bradford_Hill_criteria">Bradford Hill criteria</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=9" title="Edit section: Bradford Hill criteria"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Bradford_Hill_criteria" title="Bradford Hill criteria">Bradford Hill criteria</a></div> <p>In 1965, <a href="/wiki/Austin_Bradford_Hill" title="Austin Bradford Hill">Austin Bradford Hill</a> proposed a series of considerations to help assess evidence of causation,<sup id="cite_ref-bh65_56-0" class="reference"><a href="#cite_note-bh65-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup> which have come to be commonly known as the "<a href="/wiki/Bradford_Hill_criteria" title="Bradford Hill criteria">Bradford Hill criteria</a>". In contrast to the explicit intentions of their author, Hill's considerations are now sometimes taught as a checklist to be implemented for assessing causality.<sup id="cite_ref-57" class="reference"><a href="#cite_note-57"><span class="cite-bracket">[</span>57<span class="cite-bracket">]</span></a></sup> Hill himself said "None of my nine viewpoints can bring indisputable evidence for or against the cause-and-effect hypothesis and none can be required <i>sine qua non</i>."<sup id="cite_ref-bh65_56-1" class="reference"><a href="#cite_note-bh65-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup> </p> <ol><li><b>Strength of Association</b>: A small association does not mean that there is not a causal effect, though the larger the association, the more likely that it is causal.<sup id="cite_ref-bh65_56-2" class="reference"><a href="#cite_note-bh65-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup></li> <li><b>Consistency of Data</b>: Consistent findings observed by different persons in different places with different samples strengthens the likelihood of an effect.<sup id="cite_ref-bh65_56-3" class="reference"><a href="#cite_note-bh65-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup></li> <li><b>Specificity</b>: Causation is likely if a very specific population at a specific site and disease with no other likely explanation. The more specific an association between a factor and an effect is, the bigger the probability of a causal relationship.<sup id="cite_ref-bh65_56-4" class="reference"><a href="#cite_note-bh65-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup></li> <li><b>Temporality</b>: The effect has to occur after the cause (and if there is an expected delay between the cause and expected effect, then the effect must occur after that delay).<sup id="cite_ref-bh65_56-5" class="reference"><a href="#cite_note-bh65-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup></li> <li><b>Biological gradient</b>: Greater exposure should generally lead to greater incidence of the effect. However, in some cases, the mere presence of the factor can trigger the effect. In other cases, an inverse proportion is observed: greater exposure leads to lower incidence.<sup id="cite_ref-bh65_56-6" class="reference"><a href="#cite_note-bh65-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup></li> <li><b>Plausibility</b>: A plausible mechanism between cause and effect is helpful (but Hill noted that knowledge of the mechanism is limited by current knowledge).<sup id="cite_ref-bh65_56-7" class="reference"><a href="#cite_note-bh65-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup></li> <li><b>Coherence</b>: Coherence between epidemiological and laboratory findings increases the likelihood of an effect. However, Hill noted that "... lack of such [laboratory] evidence cannot nullify the epidemiological effect on associations".<sup id="cite_ref-bh65_56-8" class="reference"><a href="#cite_note-bh65-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup></li> <li><b>Experiment</b>: "Occasionally it is possible to appeal to experimental evidence".<sup id="cite_ref-bh65_56-9" class="reference"><a href="#cite_note-bh65-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup></li> <li><b>Analogy</b>: The effect of similar factors may be considered.<sup id="cite_ref-bh65_56-10" class="reference"><a href="#cite_note-bh65-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup></li></ol> <div class="mw-heading mw-heading3"><h3 id="Legal_interpretation">Legal interpretation</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=10" title="Edit section: Legal interpretation"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Epidemiological_study" class="mw-redirect" title="Epidemiological study">Epidemiological studies</a> can only go to prove that an agent could have caused, but not that it did cause, an effect in any particular case: </p> <style data-mw-deduplicate="TemplateStyles:r1244412712">.mw-parser-output .templatequote{overflow:hidden;margin:1em 0;padding:0 32px}.mw-parser-output .templatequotecite{line-height:1.5em;text-align:left;margin-top:0}@media(min-width:500px){.mw-parser-output .templatequotecite{padding-left:1.6em}}</style><blockquote class="templatequote"><p>Epidemiology is concerned with the <a href="/wiki/Incidence_(epidemiology)" title="Incidence (epidemiology)">incidence</a> of disease in populations and does not address the question of the cause of an individual's disease. This question, sometimes referred to as specific causation, is beyond the domain of the science of epidemiology. Epidemiology has its limits at the point where an inference is made that the relationship between an agent and a disease is causal (general causation) and where the magnitude of excess risk attributed to the agent has been determined; that is, epidemiology addresses whether an agent can cause disease, not whether an agent did cause a specific plaintiff's disease.<sup id="cite_ref-green_58-0" class="reference"><a href="#cite_note-green-58"><span class="cite-bracket">[</span>58<span class="cite-bracket">]</span></a></sup></p></blockquote> <p>In United States law, epidemiology alone cannot prove that a causal association does not exist in general. Conversely, it can be (and is in some circumstances) taken by US courts, in an individual case, to justify an inference that a causal association does exist, based upon a balance of <a href="/wiki/Probability" title="Probability">probability</a>. </p><p>The subdiscipline of forensic epidemiology is directed at the investigation of specific causation of disease or injury in individuals or groups of individuals in instances in which causation is disputed or is unclear, for presentation in legal settings. </p> <div class="mw-heading mw-heading2"><h2 id="Population-based_health_management">Population-based health management</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=11" title="Edit section: Population-based health management"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Epidemiological practice and the results of epidemiological analysis make a significant contribution to emerging population-based health management frameworks. </p><p>Population-based health management encompasses the ability to: </p> <ul><li>Assess the health states and health needs of a target population;</li> <li>Implement and evaluate interventions that are designed to improve the health of that population; and</li> <li>Efficiently and effectively provide care for members of that population in a way that is consistent with the community's cultural, policy and health resource values.</li></ul> <p>Modern population-based health management is complex, requiring a multiple set of skills (medical, political, technological, mathematical, etc.) of which epidemiological practice and analysis is a core component, that is unified with management science to provide efficient and effective health care and health guidance to a population. This task requires the forward-looking ability of modern risk management approaches that transform health risk factors, incidence, prevalence and mortality statistics (derived from epidemiological analysis) into management metrics that not only guide how a health system responds to current population health issues but also how a health system can be managed to better respond to future potential population health issues.<sup id="cite_ref-59" class="reference"><a href="#cite_note-59"><span class="cite-bracket">[</span>59<span class="cite-bracket">]</span></a></sup> </p><p>Examples of organizations that use population-based health management that leverage the work and results of epidemiological practice include Canadian Strategy for Cancer Control, Health Canada Tobacco Control Programs, Rick Hansen Foundation, Canadian Tobacco Control Research Initiative.<sup id="cite_ref-60" class="reference"><a href="#cite_note-60"><span class="cite-bracket">[</span>60<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-61" class="reference"><a href="#cite_note-61"><span class="cite-bracket">[</span>61<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-62" class="reference"><a href="#cite_note-62"><span class="cite-bracket">[</span>62<span class="cite-bracket">]</span></a></sup> </p><p>Each of these organizations uses a population-based health management framework called Life at Risk that combines epidemiological quantitative analysis with demographics, health agency operational research and economics to perform: </p> <ul><li><i>Population Life Impacts Simulations</i>: Measurement of the future potential impact of disease upon the population with respect to new disease cases, prevalence, premature death as well as potential years of life lost from disability and death;</li> <li><i>Labour Force Life Impacts Simulations</i>: Measurement of the future potential impact of disease upon the labour force with respect to new disease cases, prevalence, premature death and potential years of life lost from disability and death;</li> <li><i>Economic Impacts of Disease Simulations</i>: Measurement of the future potential impact of disease upon private sector disposable income impacts (wages, corporate profits, private health care costs) and public sector disposable income impacts (personal income tax, corporate income tax, consumption taxes, <a href="/wiki/Publicly_funded_health_care" title="Publicly funded health care">publicly funded health care</a> costs).</li></ul> <div class="mw-heading mw-heading2"><h2 id="Applied_field_epidemiology">Applied field epidemiology</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=12" title="Edit section: Applied field epidemiology"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Applied epidemiology is the practice of using epidemiological methods to protect or improve the health of a population. Applied field epidemiology can include investigating communicable and non-communicable disease outbreaks, mortality and morbidity rates, and nutritional status, among other indicators of health, with the purpose of communicating the results to those who can implement appropriate policies or disease control measures. </p> <div class="mw-heading mw-heading3"><h3 id="Humanitarian_context">Humanitarian context</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=13" title="Edit section: Humanitarian context"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>As the surveillance and reporting of diseases and other health factors become increasingly difficult in humanitarian crisis situations, the methodologies used to report the data are compromised. One study found that less than half (42.4%) of nutrition surveys sampled from humanitarian contexts correctly calculated the prevalence of malnutrition and only one-third (35.3%) of the surveys met the criteria for quality. Among the mortality surveys, only 3.2% met the criteria for quality. As nutritional status and mortality rates help indicate the severity of a crisis, the tracking and reporting of these health factors is crucial. </p><p>Vital registries are usually the most effective ways to collect data, but in humanitarian contexts these registries can be non-existent, unreliable, or inaccessible. As such, mortality is often inaccurately measured using either prospective demographic surveillance or retrospective mortality surveys. Prospective demographic surveillance requires much manpower and is difficult to implement in a spread-out population. Retrospective mortality surveys are prone to selection and reporting biases. Other methods are being developed, but are not common practice yet.<sup id="cite_ref-63" class="reference"><a href="#cite_note-63"><span class="cite-bracket">[</span>63<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-64" class="reference"><a href="#cite_note-64"><span class="cite-bracket">[</span>64<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-65" class="reference"><a href="#cite_note-65"><span class="cite-bracket">[</span>65<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-66" class="reference"><a href="#cite_note-66"><span class="cite-bracket">[</span>66<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Characterization,_validity,_and_bias"><span id="Characterization.2C_validity.2C_and_bias"></span>Characterization, validity, and bias</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=14" title="Edit section: Characterization, validity, and bias"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Epidemic_wave">Epidemic wave</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=15" title="Edit section: Epidemic wave"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The concept of waves in epidemics has implications especially for <a href="/wiki/Infection" title="Infection">communicable diseases</a>. A working definition for the term "epidemic wave" is based on two key features: 1) it comprises periods of upward or downward trends, and 2) these increases or decreases must be substantial and sustained over a period of time, in order to distinguish them from minor fluctuations or reporting errors.<sup id="cite_ref-Zhang_67-0" class="reference"><a href="#cite_note-Zhang-67"><span class="cite-bracket">[</span>67<span class="cite-bracket">]</span></a></sup> The use of a consistent scientific definition is to provide a consistent language that can be used to communicate about and understand the progression of the COVID-19 pandemic, which would aid healthcare organizations and policymakers in resource planning and allocation. </p> <div class="mw-heading mw-heading3"><h3 id="Validities">Validities</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=16" title="Edit section: Validities"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Different fields in epidemiology have different levels of validity. One way to assess the validity of findings is the ratio of false-positives (claimed effects that are not correct) to false-negatives (studies which fail to support a true effect). In <a href="/wiki/Genetic_epidemiology" title="Genetic epidemiology">genetic epidemiology</a>, candidate-gene studies may produce over 100 false-positive findings for each false-negative. By contrast genome-wide association appear close to the reverse, with only one false positive for every 100 or more false-negatives.<sup id="cite_ref-Ioannides2011_68-0" class="reference"><a href="#cite_note-Ioannides2011-68"><span class="cite-bracket">[</span>68<span class="cite-bracket">]</span></a></sup> This ratio has improved over time in genetic epidemiology, as the field has adopted stringent criteria. By contrast, other epidemiological fields have not required such rigorous reporting and are much less reliable as a result.<sup id="cite_ref-Ioannides2011_68-1" class="reference"><a href="#cite_note-Ioannides2011-68"><span class="cite-bracket">[</span>68<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Random_error">Random error</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=17" title="Edit section: Random error"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Random error is the result of fluctuations around a true value because of sampling variability. Random error is just that: random. It can occur during data collection, coding, transfer, or analysis. Examples of random errors include poorly worded questions, a misunderstanding in interpreting an individual answer from a particular respondent, or a typographical error during coding. Random error affects measurement in a transient, inconsistent manner and it is impossible to correct for random error. There is a random error in all sampling procedures – <a href="/wiki/Sampling_error" title="Sampling error">sampling error</a>.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (July 2023)">citation needed</span></a></i>]</sup> </p><p>Precision in epidemiological variables is a measure of random error. Precision is also inversely related to random error, so that to reduce random error is to increase precision. Confidence intervals are computed to demonstrate the precision of relative risk estimates. The narrower the confidence interval, the more precise the relative risk estimate. </p><p>There are two basic ways to reduce random error in an <a href="/wiki/Epidemiological_study" class="mw-redirect" title="Epidemiological study">epidemiological study</a>. The first is to increase the sample size of the study. In other words, add more subjects to your study. The second is to reduce the variability in measurement in the study. This might be accomplished by using a more precise measuring device or by increasing the number of measurements. </p><p>Note, that if sample size or number of measurements are increased, or a more precise measuring tool is purchased, the costs of the study are usually increased. There is usually an uneasy balance between the need for adequate precision and the practical issue of study cost. </p> <div class="mw-heading mw-heading3"><h3 id="Systematic_error">Systematic error</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=18" title="Edit section: Systematic error"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>A systematic error or bias occurs when there is a difference between the true value (in the population) and the observed value (in the study) from any cause other than sampling variability. An example of systematic error is if, unknown to you, the <a href="/wiki/Pulse_oximeter" class="mw-redirect" title="Pulse oximeter">pulse oximeter</a> you are using is set incorrectly and adds two points to the true value each time a measurement is taken. The measuring device could be <a href="/wiki/Accuracy_and_precision" title="Accuracy and precision">precise but not accurate</a>. Because the error happens in every instance, it is systematic. Conclusions you draw based on that data will still be incorrect. But the error can be reproduced in the future (e.g., by using the same mis-set instrument). </p><p>A mistake in coding that affects <i>all</i> responses for that particular question is another example of a systematic error. </p><p>The validity of a study is dependent on the degree of systematic error. Validity is usually separated into two components: </p> <ul><li><a href="/wiki/Internal_validity" title="Internal validity">Internal validity</a> is dependent on the amount of error in measurements, including exposure, disease, and the associations between these variables. Good internal validity implies a lack of error in measurement and suggests that inferences may be drawn at least as they pertain to the subjects under study.</li> <li><a href="/wiki/External_validity" title="External validity">External validity</a> pertains to the process of generalizing the findings of the study to the population from which the sample was drawn (or even beyond that population to a more universal statement). This requires an understanding of which conditions are relevant (or irrelevant) to the generalization. Internal validity is clearly a prerequisite for external validity.</li></ul> <div class="mw-heading mw-heading4"><h4 id="Selection_bias">Selection bias</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=19" title="Edit section: Selection bias"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Selection_bias" title="Selection bias">Selection bias</a> occurs when study subjects are selected or become part of the study as a result of a third, unmeasured variable which is associated with both the exposure and outcome of interest.<sup id="cite_ref-Hernán2004_69-0" class="reference"><a href="#cite_note-Hernán2004-69"><span class="cite-bracket">[</span>69<span class="cite-bracket">]</span></a></sup> For instance, it has repeatedly been noted that cigarette smokers and non smokers tend to differ in their study participation rates. (Sackett D cites the example of Seltzer et al., in which 85% of non smokers and 67% of smokers returned mailed questionnaires.)<sup id="cite_ref-Sackett_D._Bias_in_analytic_research._J_Chron_Dis_1979;_vol._32:51–63._70-0" class="reference"><a href="#cite_note-Sackett_D._Bias_in_analytic_research._J_Chron_Dis_1979;_vol._32:51–63.-70"><span class="cite-bracket">[</span>70<span class="cite-bracket">]</span></a></sup> Such a difference in response will not lead to bias if it is not also associated with a systematic difference in outcome between the two response groups. </p> <div class="mw-heading mw-heading4"><h4 id="Information_bias">Information bias</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=20" title="Edit section: Information bias"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Information_bias_(epidemiology)" title="Information bias (epidemiology)">Information bias</a> is bias arising from systematic error in the assessment of a variable.<sup id="cite_ref-Rothman2002_71-0" class="reference"><a href="#cite_note-Rothman2002-71"><span class="cite-bracket">[</span>71<span class="cite-bracket">]</span></a></sup> An example of this is recall bias. A typical example is again provided by Sackett in his discussion of a study examining the effect of specific exposures on fetal health: "in questioning mothers whose recent pregnancies had ended in fetal death or malformation (cases) and a matched group of mothers whose pregnancies ended normally (controls) it was found that 28% of the former, but only 20% of the latter, reported exposure to drugs which could not be substantiated either in earlier prospective interviews or in other health records".<sup id="cite_ref-Sackett_D._Bias_in_analytic_research._J_Chron_Dis_1979;_vol._32:51–63._70-1" class="reference"><a href="#cite_note-Sackett_D._Bias_in_analytic_research._J_Chron_Dis_1979;_vol._32:51–63.-70"><span class="cite-bracket">[</span>70<span class="cite-bracket">]</span></a></sup> In this example, recall bias probably occurred as a result of women who had had miscarriages having an apparent tendency to better recall and therefore report previous exposures. </p> <div class="mw-heading mw-heading4"><h4 id="Design-related_bias">Design-related bias</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=21" title="Edit section: Design-related bias"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Next to sample- and variable-related bias, bias can also arise from an imperfect study design. One example is immortal time bias, where during study period, there is some interval during which the outcome event cannot occur (making these individual "immortal").<sup id="cite_ref-72" class="reference"><a href="#cite_note-72"><span class="cite-bracket">[</span>72<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-73" class="reference"><a href="#cite_note-73"><span class="cite-bracket">[</span>73<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading4"><h4 id="Confounding">Confounding</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=22" title="Edit section: Confounding"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Confounding" title="Confounding">Confounding</a> has traditionally been defined as bias arising from the co-occurrence or mixing of effects of extraneous factors, referred to as confounders, with the main effect(s) of interest.<sup id="cite_ref-Rothman2002_71-1" class="reference"><a href="#cite_note-Rothman2002-71"><span class="cite-bracket">[</span>71<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Greenland_74-0" class="reference"><a href="#cite_note-Greenland-74"><span class="cite-bracket">[</span>74<span class="cite-bracket">]</span></a></sup> A more recent definition of confounding invokes the notion of <i>counterfactual</i> effects.<sup id="cite_ref-Greenland_74-1" class="reference"><a href="#cite_note-Greenland-74"><span class="cite-bracket">[</span>74<span class="cite-bracket">]</span></a></sup> According to this view, when one observes an outcome of interest, say Y=1 (as opposed to Y=0), in a given population A which is entirely exposed (i.e. exposure <i>X</i> = 1 for every unit of the population) the risk of this event will be <i>R</i><sub>A1</sub>. The counterfactual or unobserved risk <i>R</i><sub>A0</sub> corresponds to the risk which would have been observed if these same individuals had been unexposed (i.e. <i>X</i> = 0 for every unit of the population). The true effect of exposure therefore is: <i>R</i><sub>A1</sub> − <i>R</i><sub>A0</sub> (if one is interested in risk differences) or <i>R</i><sub>A1</sub>/<i>R</i><sub>A0</sub> (if one is interested in relative risk). Since the counterfactual risk <i>R</i><sub>A0</sub> is unobservable we approximate it using a second population B and we actually measure the following relations: <i>R</i><sub>A1</sub> − <i>R</i><sub>B0</sub> or <i>R</i><sub>A1</sub>/<i>R</i><sub>B0</sub>. In this situation, confounding occurs when <i>R</i><sub>A0</sub> ≠ <i>R</i><sub>B0</sub>.<sup id="cite_ref-Greenland_74-2" class="reference"><a href="#cite_note-Greenland-74"><span class="cite-bracket">[</span>74<span class="cite-bracket">]</span></a></sup> (NB: Example assumes binary outcome and exposure variables.) </p><p>Some epidemiologists prefer to think of confounding separately from common categorizations of bias since, unlike selection and information bias, confounding stems from real causal effects.<sup id="cite_ref-Hernán2004_69-1" class="reference"><a href="#cite_note-Hernán2004-69"><span class="cite-bracket">[</span>69<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="The_profession">The profession</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=23" title="Edit section: The profession"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Few universities have offered epidemiology as a course of study at the undergraduate level.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim is unsourced and likely incorrect. For example, I personally know that more than a "few universities" offer undergraduate-level courses in epidemiology. (July 2024)">citation needed</span></a></i>]</sup> An undergraduate program exists at <a href="/wiki/Johns_Hopkins_University" title="Johns Hopkins University">Johns Hopkins University</a> in which students who major in public health can take graduate-level courses—including epidemiology—during their senior year at the <a href="/wiki/Bloomberg_School_of_Public_Health" class="mw-redirect" title="Bloomberg School of Public Health">Bloomberg School of Public Health</a>.<sup id="cite_ref-75" class="reference"><a href="#cite_note-75"><span class="cite-bracket">[</span>75<span class="cite-bracket">]</span></a></sup> In addition to its master's and doctoral degrees in epidemiology, the <a href="/wiki/University_of_Michigan_School_of_Public_Health" title="University of Michigan School of Public Health">University of Michigan School of Public Health</a> has offered undergraduate degree programs since 2017 that include coursework in epidemiology.<sup id="cite_ref-76" class="reference"><a href="#cite_note-76"><span class="cite-bracket">[</span>76<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-77" class="reference"><a href="#cite_note-77"><span class="cite-bracket">[</span>77<span class="cite-bracket">]</span></a></sup> </p><p>Although epidemiologic research is conducted by individuals from diverse disciplines, variable levels of training in epidemiologic methods are provided during <a href="/wiki/Pharmacy_school" title="Pharmacy school">pharmacy</a>, <a href="/wiki/Medical_education" title="Medical education">medical</a>, <a href="/wiki/Veterinary_education" title="Veterinary education">veterinary</a>, <a href="/wiki/Social_work#Theoretical_models_and_practices" title="Social work">social work</a>, <a href="/wiki/Podiatric_medical_school" title="Podiatric medical school">podiatry</a>, <a href="/wiki/Public_health_nursing" title="Public health nursing">nursing</a>, <a href="/wiki/Doctor_of_Physical_Therapy#Professional_degree_(entry-level)" title="Doctor of Physical Therapy">physical therapy</a>, and <a href="/wiki/Psychologist#United_States" title="Psychologist">clinical psychology</a> doctoral programs in addition to the formal training master's and doctoral students in public health fields receive. </p><p>As public health practitioners, epidemiologists work in a number of different settings. Some epidemiologists work "in the field" (i.e., in the community; commonly<sup class="noprint Inline-Template" style="margin-left:0.1em; white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Manual_of_Style/Words_to_watch#Unsupported_attributions" title="Wikipedia:Manual of Style/Words to watch"><span title="The material near this tag may use weasel words or too-vague attribution. (July 2024)">according to whom?</span></a></i>]</sup> in a public health service), and are often at the forefront of investigating and combating disease outbreaks.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="Why are epidemiologists working in the field often at the forefront of infectious disease outbreaks? I mean... I know the reason why, but the average reader might not. (July 2024)">citation needed</span></a></i>]</sup> Others work for non-profit organizations, universities, hospitals, or larger government entities (e.g., state and local health departments in the United States), ministries of health, <a href="/wiki/M%C3%A9decins_Sans_Fronti%C3%A8res" title="Médecins Sans Frontières">Doctors without Borders</a>, the <a href="/wiki/Centers_for_Disease_Control_and_Prevention" title="Centers for Disease Control and Prevention">Centers for Disease Control and Prevention</a> (CDC), the <a href="/wiki/Health_Protection_Agency" title="Health Protection Agency">Health Protection Agency</a>, the <a href="/wiki/World_Health_Organization" title="World Health Organization">World Health Organization</a> (WHO), or the <a href="/wiki/Public_Health_Agency_of_Canada" title="Public Health Agency of Canada">Public Health Agency of Canada</a>. Epidemiologists can also work in for-profit organizations (e.g., pharmaceutical and medical device companies) in groups such as market research or clinical development. </p> <div class="mw-heading mw-heading3"><h3 id="COVID-19">COVID-19</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=24" title="Edit section: COVID-19"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>An April 2020 <a href="/wiki/University_of_Southern_California" title="University of Southern California">University of Southern California</a> article noted that, "The <a href="/wiki/Coronavirus_epidemic" class="mw-redirect" title="Coronavirus epidemic">coronavirus epidemic</a>... thrust epidemiology – the study of the incidence, distribution and control of disease in a population – to the forefront of scientific disciplines across the globe and even made temporary celebrities out of some of its practitioners."<sup id="cite_ref-78" class="reference"><a href="#cite_note-78"><span class="cite-bracket">[</span>78<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=25" title="Edit section: See also"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1266661725">.mw-parser-output .portalbox{padding:0;margin:0.5em 0;display:table;box-sizing:border-box;max-width:175px;list-style:none}.mw-parser-output .portalborder{border:1px solid var(--border-color-base,#a2a9b1);padding:0.1em;background:var(--background-color-neutral-subtle,#f8f9fa)}.mw-parser-output .portalbox-entry{display:table-row;font-size:85%;line-height:110%;height:1.9em;font-style:italic;font-weight:bold}.mw-parser-output .portalbox-image{display:table-cell;padding:0.2em;vertical-align:middle;text-align:center}.mw-parser-output .portalbox-link{display:table-cell;padding:0.2em 0.2em 0.2em 0.3em;vertical-align:middle}@media(min-width:720px){.mw-parser-output .portalleft{margin:0.5em 1em 0.5em 0}.mw-parser-output .portalright{clear:right;float:right;margin:0.5em 0 0.5em 1em}}</style><ul role="navigation" aria-label="Portals" class="noprint portalbox portalborder portalright"> <li class="portalbox-entry"><span class="portalbox-image"><span class="noviewer" typeof="mw:File"><span><img alt="icon" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/WHO_Rod.svg/12px-WHO_Rod.svg.png" decoding="async" width="12" height="28" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/WHO_Rod.svg/18px-WHO_Rod.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d6/WHO_Rod.svg/24px-WHO_Rod.svg.png 2x" data-file-width="107" data-file-height="250" /></span></span></span><span class="portalbox-link"><a href="/wiki/Portal:Medicine" title="Portal:Medicine">Medicine portal</a></span></li></ul> <style data-mw-deduplicate="TemplateStyles:r1184024115">.mw-parser-output .div-col{margin-top:0.3em;column-width:30em}.mw-parser-output .div-col-small{font-size:90%}.mw-parser-output .div-col-rules{column-rule:1px solid #aaa}.mw-parser-output .div-col dl,.mw-parser-output .div-col ol,.mw-parser-output .div-col ul{margin-top:0}.mw-parser-output .div-col li,.mw-parser-output .div-col dd{page-break-inside:avoid;break-inside:avoid-column}</style><div class="div-col"> <ul><li><a href="/wiki/Age_adjustment" title="Age adjustment">Age adjustment</a> – Technique used to compare populations with different age profiles</li> <li><a href="/wiki/Caerphilly_Heart_Disease_Study" title="Caerphilly Heart Disease Study">Caerphilly Heart Disease Study</a> – Medical research project</li> <li><a href="/wiki/Centre_for_Research_on_the_Epidemiology_of_Disasters" title="Centre for Research on the Epidemiology of Disasters">Centre for Research on the Epidemiology of Disasters</a> (<abbr>CRED</abbr>)</li> <li><a href="/wiki/Centro_Studi_GISED" title="Centro Studi GISED">Centro Studi GISED</a></li> <li><a href="/wiki/Circulation_plan" title="Circulation plan">Circulation plan</a></li> <li><a href="/wiki/Contact_tracing" title="Contact tracing">Contact tracing</a> – Finding and identifying people in contact with someone with an infectious disease</li> <li><a href="/wiki/Critical_community_size" title="Critical community size">Critical community size</a> – Minimum size of a closed population within which a pathogen can persist indefinitely</li> <li><a href="/wiki/Disease_cluster" title="Disease cluster">Disease cluster</a> – Large incidence of a medical condition in a particular location or time frame</li> <li><a href="/wiki/Disease_diffusion_mapping" title="Disease diffusion mapping">Disease diffusion mapping</a> – Map of disease risk for a region</li> <li><a href="/wiki/Compartmental_models_in_epidemiology" title="Compartmental models in epidemiology">Compartmental models in epidemiology</a> – Type of mathematical model used for infectious diseases</li> <li><a href="/wiki/Epidemiological_method" title="Epidemiological method">Epidemiological method</a> – Scientific method in the specific field</li> <li><a href="/wiki/Epidemiological_transition" title="Epidemiological transition">Epidemiological transition</a> – A term in demography</li> <li><a href="/wiki/European_Centre_for_Disease_Prevention_and_Control" title="European Centre for Disease Prevention and Control">European Centre for Disease Prevention and Control</a> – Agency of the European Union</li> <li><a href="/wiki/Hispanic_paradox" title="Hispanic paradox">Hispanic paradox</a> – Epidemiological finding</li> <li><a href="/wiki/International_Society_for_Pharmacoepidemiology" title="International Society for Pharmacoepidemiology">International Society for Pharmacoepidemiology</a></li> <li><a href="/wiki/Job-exposure_matrix" title="Job-exposure matrix">Job-exposure matrix</a> – means of estimating a person's history of occupational exposure<span style="display:none" class="category-wikidata-fallback-annotation">Pages displaying wikidata descriptions as a fallback</span></li> <li><a href="/wiki/Mathematical_modelling_of_infectious_disease" class="mw-redirect" title="Mathematical modelling of infectious disease">Mathematical modelling of infectious disease</a> – Using mathematical models to understand infectious disease transmission<span style="display:none" class="category-annotation-with-redirected-description">Pages displaying short descriptions of redirect targets</span></li> <li><a href="/wiki/Mendelian_randomization" title="Mendelian randomization">Mendelian randomization</a> – Statistical method in genetic epidemiology</li> <li><a href="/wiki/Occupational_epidemiology" title="Occupational epidemiology">Occupational epidemiology</a> – Epidemiology of workplaces diseases</li> <li><a href="/wiki/Predictive_analytics" title="Predictive analytics">Predictive analytics</a> – Statistical techniques analyzing facts to make predictions about unknown events</li> <li><a href="/wiki/Society_for_Occupational_Health_Psychology" title="Society for Occupational Health Psychology"><i>Society for Occupational Health Psychology</i></a> – American occupational health psychology organization</li> <li><a href="/wiki/Race_and_health" title="Race and health">Population groups in biomedicine</a> – Health based on racial identity</li> <li><a href="/wiki/Spatial_epidemiology" title="Spatial epidemiology">Spatial epidemiology</a> – subfield of health geography focused on the study of the spatial distribution of health outcomes<span style="display:none" class="category-wikidata-fallback-annotation">Pages displaying wikidata descriptions as a fallback</span></li> <li><a href="/wiki/Study_of_Health_in_Pomerania" title="Study of Health in Pomerania">Study of Health in Pomerania</a></li> <li><a href="/wiki/Targeted_immunization_strategies" title="Targeted immunization strategies">Targeted immunization strategies</a></li> <li><a href="/wiki/Urban_planning" title="Urban planning">Urban planning</a> – Technical and political process of land use and urban design</li> <li><a href="/wiki/Whitehall_Study" title="Whitehall Study">Whitehall Study</a> – Health study of British civil servants</li> <li><a href="/wiki/Zoonosis" title="Zoonosis">Zoonosis</a> – Disease that can be transmitted from other species to humans</li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=26" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Citations">Citations</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=27" title="Edit section: Citations"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFPorta2014" class="citation book cs1">Porta M (2014). <a rel="nofollow" class="external text" href="http://global.oup.com/academic/product/a-dictionary-of-epidemiology-9780199976737?cc=us&lang=en"><i>A Dictionary of Epidemiology</i></a> (6th ed.). New York: Oxford University Press. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-19-997673-7" title="Special:BookSources/978-0-19-997673-7"><bdi>978-0-19-997673-7</bdi></a><span class="reference-accessdate">. Retrieved <span class="nowrap">16 July</span> 2014</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=A+Dictionary+of+Epidemiology&rft.place=New+York&rft.edition=6th&rft.pub=Oxford+University+Press&rft.date=2014&rft.isbn=978-0-19-997673-7&rft.aulast=Porta&rft.aufirst=Miquel&rft_id=http%3A%2F%2Fglobal.oup.com%2Facademic%2Fproduct%2Fa-dictionary-of-epidemiology-9780199976737%3Fcc%3Dus%26lang%3Den&rfr_id=info%3Asid%2Fen.wikipedia.org%3AEpidemiology" class="Z3988"></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFNutter1999" class="citation journal cs1">Nutter F Jr (1999). "Understanding the interrelationships between botanical, human, and veterinary epidemiology: the Ys and Rs of it all". <i>Ecosystem Health</i>. <b>5</b> (3): <span class="nowrap">131–</span>40. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1046%2Fj.1526-0992.1999.09922.x">10.1046/j.1526-0992.1999.09922.x</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Ecosystem+Health&rft.atitle=Understanding+the+interrelationships+between+botanical%2C+human%2C+and+veterinary+epidemiology%3A+the+Ys+and+Rs+of+it+all&rft.volume=5&rft.issue=3&rft.pages=%3Cspan+class%3D%22nowrap%22%3E131-%3C%2Fspan%3E40&rft.date=1999&rft_id=info%3Adoi%2F10.1046%2Fj.1526-0992.1999.09922.x&rft.aulast=Nutter&rft.aufirst=F.W.+Jr.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AEpidemiology" class="Z3988"></span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text">Hippocrates (~200 BC). <i>Airs, Waters, Places</i>.</span> </li> <li id="cite_note-Carol_Buck_1998_p3-4"><span class="mw-cite-backlink">^ <a href="#cite_ref-Carol_Buck_1998_p3_4-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Carol_Buck_1998_p3_4-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text">Carol Buck, Alvaro Llopis; Enrique Nájera; Milton Terris (1998) <i>The Challenge of Epidemiology: Issues and Selected Readings</i>. Scientific Publication No. 505. Pan American Health Organization. Washington, DC. p. 3.</span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-5">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAlfredo_Morabia2004" class="citation book cs1">Alfredo Morabia (2004). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=E-OZbEmPSTkC&pg=PA93"><i>A history of epidemiologic methods and concepts</i></a>. Birkhäuser. p. 93. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-3-7643-6818-0" title="Special:BookSources/978-3-7643-6818-0"><bdi>978-3-7643-6818-0</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=A+history+of+epidemiologic+methods+and+concepts&rft.pages=93&rft.pub=Birkh%C3%A4user&rft.date=2004&rft.isbn=978-3-7643-6818-0&rft.au=Alfredo+Morabia&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DE-OZbEmPSTkC%26pg%3DPA93&rfr_id=info%3Asid%2Fen.wikipedia.org%3AEpidemiology" class="Z3988"></span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-6">^</a></b></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://samples.jbpub.com/9780763766221/66221_CH02_5398.pdf">Historical Developments in Epidemiology</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20180219135301/http://samples.jbpub.com/9780763766221/66221_CH02_5398.pdf">Archived</a> 19 February 2018 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a>. Chapter 2. Jones & Bartlett Learning LLC.</span> </li> <li id="cite_note-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-7">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFRay_M._Merrill2010" class="citation book cs1">Ray M. Merrill (2010). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=RMDBh6gw1_UC&pg=PA24"><i>Introduction to Epidemiology</i></a>. Jones & Bartlett Learning. p. 24. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-7637-6622-1" title="Special:BookSources/978-0-7637-6622-1"><bdi>978-0-7637-6622-1</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Introduction+to+Epidemiology&rft.pages=24&rft.pub=Jones+%26+Bartlett+Learning&rft.date=2010&rft.isbn=978-0-7637-6622-1&rft.au=Ray+M.+Merrill&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DRMDBh6gw1_UC%26pg%3DPA24&rfr_id=info%3Asid%2Fen.wikipedia.org%3AEpidemiology" class="Z3988"></span></span> </li> <li id="cite_note-Merril,_Ray_M._2010-8"><span class="mw-cite-backlink">^ <a href="#cite_ref-Merril,_Ray_M._2010_8-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Merril,_Ray_M._2010_8-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text">Merril, Ray M., PhD, MPH. (2010): <i>An Introduction to Epidemiology</i>, Fifth Edition. Chapter 2: "Historic Developments in Epidemiology". Jones and Bartlett Publishing</span> </li> <li id="cite_note-hip-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-hip_9-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20110725065539/http://www.duncan-associates.com/changing_concepts.pdf">"Changing Concepts: Background to Epidemiology"</a> <span class="cs1-format">(PDF)</span>. Duncan & Associates. Archived from <a rel="nofollow" class="external text" href="http://www.duncan-associates.com/changing_concepts.pdf">the original</a> <span class="cs1-format">(PDF)</span> on 25 July 2011<span class="reference-accessdate">. Retrieved <span class="nowrap">3 February</span> 2008</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Changing+Concepts%3A+Background+to+Epidemiology&rft.pub=Duncan+%26+Associates&rft_id=http%3A%2F%2Fwww.duncan-associates.com%2Fchanging_concepts.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AEpidemiology" class="Z3988"></span></span> </li> <li id="cite_note-10"><span class="mw-cite-backlink"><b><a href="#cite_ref-10">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFJoseph2012" class="citation book cs1">Joseph PB (2012). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=AppsDAKOW3QC&pg=PA76"><i>Encyclopedia of the Black Death</i></a>. ABC-CLIO. p. 76. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-1598842548" title="Special:BookSources/978-1598842548"><bdi>978-1598842548</bdi></a><span class="reference-accessdate">. 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Retrieved <span class="nowrap">11 June</span> 2020</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Ask+the+Expert%3A+The+Epidemiology+of+COVID-19&rft.pub=SCUSM&rft.aulast=Hiro&rft.aufirst=Brian&rft_id=https%3A%2F%2Fnews.csusm.edu%2Fask-the-expert-deborah-morton%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AEpidemiology" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading3"><h3 id="Sources">Sources</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=28" title="Edit section: Sources"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239549316">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin" style=""> <ul><li><a href="/wiki/David_Clayton" title="David Clayton">Clayton, David</a> and Michael Hills (1993) <i>Statistical Models in Epidemiology</i> Oxford University Press. <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/0-19-852221-5" title="Special:BookSources/0-19-852221-5">0-19-852221-5</a></li> <li><a href="/wiki/Miquel_Porta" title="Miquel Porta">Miquel Porta</a>, editor (2014) "A dictionary of epidemiology", 6th edn, New York: Oxford University Press. <a rel="nofollow" class="external text" href="http://global.oup.com/academic/product/a-dictionary-of-epidemiology-9780199976737?cc=us&lang=en">A Dictionary of Epidemiology</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20170711233713/https://global.oup.com/academic/product/a-dictionary-of-epidemiology-9780199976737?cc=us&lang=en">Archived</a> 11 July 2017 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a></li> <li>Morabia, Alfredo, editor. (2004) A History of Epidemiologic Methods and Concepts. Basel, Birkhauser Verlag. Part I. <a rel="nofollow" class="external text" href="https://books.google.com/books?id=Hgnnhu1ym-8C">A History of Epidemiologic Methods and Concepts</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20220630015958/https://books.google.com/books?id=Hgnnhu1ym-8C&printsec=frontcover">Archived</a> 30 June 2022 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a> <a rel="nofollow" class="external text" href="https://www.springer.com/public+health/book/978-3-7643-6818-0">A History of Epidemiologic Methods and Concepts</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20110703131648/http://www.springer.com/public+health/book/978-3-7643-6818-0">Archived</a> 3 July 2011 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a></li> <li>Smetanin P, Kobak P, Moyer C, Maley O (2005). "The Risk Management of Tobacco Control Research Policy Programs" The World Conference on Tobacco OR Health Conference, 12–15 July 2006, Washington DC.</li> <li>Szklo M, Nieto FJ (2002). "Epidemiology: beyond the basics", Aspen Publishers.</li> <li>Robertson LS (2015). Injury Epidemiology: Fourth Edition. Free online at <code>nanlee.net</code></li> <li>Rothman K., <a href="/wiki/Sander_Greenland" title="Sander Greenland">Sander Greenland</a>, Lash T., editors (2008). "Modern Epidemiology", 3rd Edition, Lippincott Williams & Wilkins. <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/0-7817-5564-6" title="Special:BookSources/0-7817-5564-6">0-7817-5564-6</a>, <a href="/wiki/Special:BookSources/978-0-7817-5564-1" title="Special:BookSources/978-0-7817-5564-1">978-0-7817-5564-1</a></li> <li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20130518044530/https://skydrive.live.com/?cid=ec4d1867f6389ec0&id=EC4D1867F6389EC0%21183">Olsen J, Christensen K, Murray J, Ekbom A. An Introduction to Epidemiology for Health Professionals. New York: Springer Science+Business Media; 2010</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-1-4419-1497-2" title="Special:BookSources/978-1-4419-1497-2">978-1-4419-1497-2</a></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Epidemiology&action=edit&section=29" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1235681985">.mw-parser-output .side-box{margin:4px 0;box-sizing:border-box;border:1px solid #aaa;font-size:88%;line-height:1.25em;background-color:var(--background-color-interactive-subtle,#f8f9fa);display:flow-root}.mw-parser-output .side-box-abovebelow,.mw-parser-output .side-box-text{padding:0.25em 0.9em}.mw-parser-output .side-box-image{padding:2px 0 2px 0.9em;text-align:center}.mw-parser-output .side-box-imageright{padding:2px 0.9em 2px 0;text-align:center}@media(min-width:500px){.mw-parser-output .side-box-flex{display:flex;align-items:center}.mw-parser-output .side-box-text{flex:1;min-width:0}}@media(min-width:720px){.mw-parser-output .side-box{width:238px}.mw-parser-output .side-box-right{clear:right;float:right;margin-left:1em}.mw-parser-output .side-box-left{margin-right:1em}}</style><style data-mw-deduplicate="TemplateStyles:r1237033735">@media print{body.ns-0 .mw-parser-output .sistersitebox{display:none!important}}@media screen{html.skin-theme-clientpref-night .mw-parser-output .sistersitebox img[src*="Wiktionary-logo-en-v2.svg"]{background-color:white}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .sistersitebox img[src*="Wiktionary-logo-en-v2.svg"]{background-color:white}}</style><div class="side-box side-box-right plainlinks sistersitebox"><style data-mw-deduplicate="TemplateStyles:r1126788409">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style> <div class="side-box-flex"> <div class="side-box-image"><span class="noviewer" typeof="mw:File"><a href="/wiki/File:Commons-logo.svg" class="mw-file-description"><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png" decoding="async" width="30" height="40" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/45px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/59px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></a></span></div> <div class="side-box-text plainlist">Wikimedia Commons has media related to <span style="font-weight: bold; font-style: italic;"><a href="https://commons.wikimedia.org/wiki/Category:Epidemiology" class="extiw" title="commons:Category:Epidemiology">Epidemiology</a></span>.</div></div> </div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1235681985"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1237033735"><div class="side-box side-box-right plainlinks sistersitebox"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"> <div class="side-box-flex"> <div class="side-box-image"><span class="noviewer" typeof="mw:File"><a href="/wiki/File:Wiktionary-logo-en-v2.svg" class="mw-file-description"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/99/Wiktionary-logo-en-v2.svg/40px-Wiktionary-logo-en-v2.svg.png" decoding="async" width="40" height="40" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/99/Wiktionary-logo-en-v2.svg/60px-Wiktionary-logo-en-v2.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/99/Wiktionary-logo-en-v2.svg/80px-Wiktionary-logo-en-v2.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></div> <div class="side-box-text plainlist">Look up <i><b><a href="https://en.wiktionary.org/wiki/epidemiology" class="extiw" title="wiktionary:epidemiology">epidemiology</a></b></i> in Wiktionary, the free dictionary.</div></div> </div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1235681985"><div class="side-box metadata side-box-right"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"> <div class="side-box-abovebelow"> <a href="/wiki/Wikipedia:The_Wikipedia_Library" title="Wikipedia:The Wikipedia Library">Library resources</a> about <br /> <b>epidemiology</b> <hr /></div> <div class="side-box-flex"> <div class="side-box-text plainlist"><ul><li><a class="external text" href="https://ftl.toolforge.org/cgi-bin/ftl?st=wp&su=Epidemiology">Resources in your library</a></li> </ul></div></div> </div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239549316"><div class="refbegin" style=""> <ul><li><a rel="nofollow" class="external text" href="http://www.hpa.org.uk">The Health Protection Agency</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20070129123642/http://www.hpa.org.uk/">Archived</a> 29 January 2007 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a></li> <li><a rel="nofollow" class="external text" href="https://biostats.bepress.com/">The Collection of Biostatistics Research Archive</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20211024171703/https://biostats.bepress.com/">Archived</a> 24 October 2021 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a></li> <li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20110726171127/http://www.iea-europe.org/index.htm">European Epidemiological Federation</a></li> <li><a rel="nofollow" class="external text" href="http://www.bmj.com/about-bmj/resources-readers/publications/epidemiology-uninitiated">'Epidemiology for the Uninitiated'</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20190321191234/https://www.bmj.com/about-bmj/resources-readers/publications/epidemiology-uninitiated">Archived</a> 21 March 2019 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a> by D. Coggon, G. Rose, D.J.P. Barker, <i><a href="/wiki/British_Medical_Journal" class="mw-redirect" title="British Medical Journal">British Medical Journal</a></i></li> <li><a rel="nofollow" class="external text" href="http://www.epidem.com">Epidem.com</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20010924091113/http://epidem.com/">Archived</a> 24 September 2001 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a> – <i><a href="/wiki/Epidemiology_(journal)" title="Epidemiology (journal)">Epidemiology</a></i> (peer-reviewed scientific journal that publishes original research on epidemiologic topics)</li> <li><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/books/NBK7993/">'Epidemiology'</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20210429152443/https://www.ncbi.nlm.nih.gov/books/NBK7993/">Archived</a> 29 April 2021 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a> – In: Philip S. Brachman, <i><a href="/wiki/Medical_Microbiology" class="mw-redirect" title="Medical Microbiology">Medical Microbiology</a></i> (fourth edition), US <a href="/wiki/National_Center_for_Biotechnology_Information" title="National Center for Biotechnology Information">National Center for Biotechnology Information</a></li> <li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20071104183725/http://vlab.infotech.monash.edu.au/simulations/cellular-automata/epidemic/">Monash Virtual Laboratory</a> – Simulations of epidemic spread across a landscape</li> <li><a rel="nofollow" class="external text" href="https://dceg.cancer.gov/">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20090812223649/http://dceg.cancer.gov/">Archived</a> 12 August 2009 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a></li> <li><a rel="nofollow" class="external text" href="http://www.cred.be">Centre for Research on the Epidemiology of Disasters</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20100315094506/http://www.cred.be/">Archived</a> 15 March 2010 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a> – A <a href="/wiki/World_Health_Organization" title="World Health Organization">WHO</a> collaborating centre</li> <li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20180405101243/http://www.epidemiology.ch/history/PeopleEpidemiologyLibrary.html">People's Epidemiology Library</a></li> <li><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/32113704">Epidemiology of COVID-19 outbreak</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20200328061221/https://www.ncbi.nlm.nih.gov/pubmed/32113704">Archived</a> 28 March 2020 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a></li></ul> </div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><style data-mw-deduplicate="TemplateStyles:r1236075235">.mw-parser-output .navbox{box-sizing:border-box;border:1px solid #a2a9b1;width:100%;clear:both;font-size:88%;text-align:center;padding:1px;margin:1em auto 0}.mw-parser-output .navbox .navbox{margin-top:0}.mw-parser-output .navbox+.navbox,.mw-parser-output .navbox+.navbox-styles+.navbox{margin-top:-1px}.mw-parser-output .navbox-inner,.mw-parser-output .navbox-subgroup{width:100%}.mw-parser-output .navbox-group,.mw-parser-output .navbox-title,.mw-parser-output .navbox-abovebelow{padding:0.25em 1em;line-height:1.5em;text-align:center}.mw-parser-output .navbox-group{white-space:nowrap;text-align:right}.mw-parser-output .navbox,.mw-parser-output .navbox-subgroup{background-color:#fdfdfd}.mw-parser-output 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studies"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Medical_research_studies" title="Template talk:Medical research studies"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Medical_research_studies" title="Special:EditPage/Template:Medical research studies"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Clinical_research_and_experimental_design505" style="font-size:114%;margin:0 4em"><a href="/wiki/Clinical_research" title="Clinical research">Clinical research</a> and <a href="/wiki/Design_of_experiments" title="Design of experiments">experimental design</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Overview</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Clinical_trial" title="Clinical trial">Clinical trial</a> <ul><li><a href="/wiki/Protocol_(science)" title="Protocol (science)">Trial protocols</a></li> <li><a href="/wiki/Adaptive_clinical_trial" class="mw-redirect" title="Adaptive clinical trial">Adaptive clinical trial</a></li></ul></li> <li><a href="/wiki/Academic_clinical_trials" class="mw-redirect" title="Academic clinical trials">Academic clinical trials</a></li> <li><a href="/wiki/Clinical_study_design" title="Clinical study design">Clinical study design</a></li> <li><a href="/wiki/Evidence-based_medicine" title="Evidence-based medicine">Evidence-based medicine</a></li> <li><a href="/wiki/Real_world_evidence" title="Real world evidence">Real world evidence</a></li> <li><a href="/wiki/Patient_and_public_involvement" title="Patient and public involvement">Patient and public involvement</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Scientific_control" title="Scientific control">Controlled study</a><br />(<a href="/wiki/Hierarchy_of_evidence#USA" title="Hierarchy of evidence">EBM I to II-1</a>)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Randomized_controlled_trial" title="Randomized controlled trial">Randomized controlled trial</a> <ul><li><a href="/wiki/Experiment" title="Experiment">Scientific experiment</a></li> <li><a href="/wiki/Blind_experiment" class="mw-redirect" title="Blind experiment">Blind experiment</a></li> <li><a href="/wiki/Open-label_trial" title="Open-label trial">Open-label trial</a></li></ul></li> <li><a href="/wiki/Adaptive_clinical_trial" class="mw-redirect" title="Adaptive clinical trial">Adaptive clinical trial</a> <ul><li><a href="/wiki/Platform_trial" title="Platform trial">Platform trial</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Observational_study" title="Observational study">Observational study</a><br />(<a href="/wiki/Hierarchy_of_evidence#USA" title="Hierarchy of evidence">EBM II-2 to II-3</a>)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cross-sectional_study" title="Cross-sectional study">Cross-sectional study</a> vs. <a href="/wiki/Longitudinal_study" title="Longitudinal study">Longitudinal study</a>, <a href="/wiki/Ecological_study" title="Ecological study">Ecological study</a></li> <li><a href="/wiki/Cohort_study" title="Cohort study">Cohort study</a> <ul><li><a href="/wiki/Retrospective_cohort_study" title="Retrospective cohort study">Retrospective</a></li> <li><a href="/wiki/Prospective_cohort_study" title="Prospective cohort study">Prospective</a></li></ul></li> <li><a href="/wiki/Case%E2%80%93control_study" title="Case–control study">Case–control study</a> (<a href="/wiki/Nested_case%E2%80%93control_study" title="Nested case–control study">Nested case–control study</a>)</li> <li><a href="/wiki/Case_series" title="Case series">Case series</a></li> <li><a href="/wiki/Case_study" title="Case study">Case study</a></li> <li><a href="/wiki/Case_report" title="Case report">Case report</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Outcome_measure" title="Outcome measure">Measures</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Epidemiological_methods#Measures_of_occurrence" class="mw-redirect" title="Epidemiological methods">Occurrence</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Incidence_(epidemiology)" title="Incidence (epidemiology)">Incidence</a>, <a href="/wiki/Cumulative_incidence" class="mw-redirect" title="Cumulative incidence">Cumulative incidence</a>, <a href="/wiki/Prevalence" title="Prevalence">Prevalence</a>, <a href="/wiki/Point_prevalence" class="mw-redirect" title="Point prevalence">Point prevalence</a>, <a href="/wiki/Period_prevalence" class="mw-redirect" title="Period prevalence">Period prevalence</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Epidemiological_methods#Measures_of_association" class="mw-redirect" title="Epidemiological methods">Association</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Risk_difference" title="Risk difference">Risk difference</a>, <a href="/wiki/Number_needed_to_treat" title="Number needed to treat">Number needed to treat</a>, <a href="/wiki/Number_needed_to_harm" title="Number needed to harm">Number needed to harm</a>, <a href="/wiki/Risk_ratio" class="mw-redirect" title="Risk ratio">Risk ratio</a>, <a href="/wiki/Relative_risk_reduction" title="Relative risk reduction">Relative risk reduction</a>, <a href="/wiki/Odds_ratio" title="Odds ratio">Odds ratio</a>, <a href="/wiki/Hazard_ratio" title="Hazard ratio">Hazard ratio</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Population_impact_measure" title="Population impact measure">Population impact</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Attributable_fraction_among_the_exposed" title="Attributable fraction among the exposed">Attributable fraction among the exposed</a>, <a href="/wiki/Attributable_fraction_for_the_population" title="Attributable fraction for the population">Attributable fraction for the population</a>, <a href="/wiki/Preventable_fraction_among_the_unexposed" title="Preventable fraction among the unexposed">Preventable fraction among the unexposed</a>, <a href="/wiki/Preventable_fraction_for_the_population" title="Preventable fraction for the population">Preventable fraction for the population</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Epidemiological_methods#Other_measures" class="mw-redirect" title="Epidemiological methods">Other</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Clinical_endpoint" title="Clinical endpoint">Clinical endpoint</a>, <a href="/wiki/Virulence" title="Virulence">Virulence</a>, <a href="/wiki/Infectivity" title="Infectivity">Infectivity</a>, <a href="/wiki/Mortality_rate" title="Mortality rate">Mortality rate</a>, <a href="/wiki/Morbidity" class="mw-redirect" title="Morbidity">Morbidity</a>, <a href="/wiki/Case_fatality_rate" title="Case fatality rate">Case fatality rate</a>, <a href="/wiki/Specificity_and_sensitivity" class="mw-redirect" title="Specificity and sensitivity">Specificity and sensitivity</a>, <a href="/wiki/Likelihood_ratios_in_diagnostic_testing" title="Likelihood ratios in diagnostic testing">Likelihood-ratios</a>, <a href="/wiki/Pre-_and_post-test_probability" title="Pre- and post-test probability">Pre- and post-test probability</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Trial/test types</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/In_vitro" title="In vitro">In vitro</a></li> <li><a href="/wiki/In_vivo" title="In vivo">In vivo</a></li> <li><a href="/wiki/Animal_testing" title="Animal testing">Animal testing</a></li> <li><a href="/wiki/Animal_testing_on_non-human_primates" title="Animal testing on non-human primates">Animal testing on non-human primates</a></li> <li><a href="/wiki/First-in-man_study" class="mw-redirect" title="First-in-man study">First-in-man study</a></li> <li><a href="/wiki/Multicenter_trial" title="Multicenter trial">Multicenter trial</a></li> <li><a href="/wiki/Seeding_trial" title="Seeding trial">Seeding trial</a></li> <li><a href="/wiki/Vaccine_trial" title="Vaccine trial">Vaccine trial</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Analysis_of_clinical_trials" title="Analysis of clinical trials">Analysis of clinical trials</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Risk%E2%80%93benefit_ratio" title="Risk–benefit ratio">Risk–benefit ratio</a></li> <li><a href="/wiki/Systematic_review" title="Systematic review">Systematic review</a></li> <li><a href="/wiki/Reproducibility" title="Reproducibility">Replication</a></li> <li><a href="/wiki/Meta-analysis" title="Meta-analysis">Meta-analysis</a></li> <li><a href="/wiki/Intention-to-treat_analysis" title="Intention-to-treat analysis">Intention-to-treat analysis</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Interpretation of results</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Selection_bias" title="Selection bias">Selection bias</a></li> <li><a href="/wiki/Survivorship_bias" title="Survivorship bias">Survivorship bias</a></li> <li><a href="/wiki/Correlation_does_not_imply_causation" title="Correlation does not imply causation">Correlation does not imply causation</a></li> <li><a href="/wiki/Null_result" title="Null result">Null result</a></li> <li><a href="/wiki/Sex_as_a_biological_variable" title="Sex as a biological variable">Sex as a biological variable</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <ul><li><b><a href="/wiki/Category:Clinical_research" title="Category:Clinical research">Category</a></b></li> <li><b><a href="/wiki/Glossary_of_clinical_research" title="Glossary of clinical research">Glossary</a></b></li> <li><b><a href="/wiki/List_of_clinical_research_topics" class="mw-redirect" title="List of clinical research topics">List of topics</a></b></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Public_health650" style="padding:3px"><table class="nowraplinks hlist mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Public_health" title="Template:Public health"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Public_health" title="Template talk:Public health"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Public_health" title="Special:EditPage/Template:Public health"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Public_health650" style="font-size:114%;margin:0 4em"><a href="/wiki/Public_health" title="Public health">Public health</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">General</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Auxology" title="Auxology">Auxology</a></li> <li><a href="/wiki/Biological_hazard" title="Biological hazard">Biological hazard</a></li> <li><a href="/wiki/Chief_Medical_Officer" class="mw-redirect" title="Chief Medical Officer">Chief Medical Officer</a></li> <li><a href="/wiki/Cultural_competence_in_health_care" class="mw-redirect" title="Cultural competence in health care">Cultural competence</a></li> <li><a href="/wiki/Deviance_(sociology)" title="Deviance (sociology)">Deviance</a></li> <li><a href="/wiki/Environmental_health" title="Environmental health">Environmental health</a></li> <li><a href="/wiki/Eugenics" title="Eugenics">Eugenics</a> <ul><li><a href="/wiki/History_of_eugenics" title="History of eugenics">History of</a></li> <li><a href="/wiki/New_eugenics" title="New eugenics">Liberal</a></li></ul></li> <li><a href="/wiki/Euthenics" title="Euthenics">Euthenics</a></li> <li><a href="/wiki/Public_health_genomics" title="Public health genomics">Genomics</a></li> <li><a href="/wiki/Globalization_and_disease" title="Globalization and disease">Globalization and disease</a></li> <li><a href="/wiki/Harm_reduction" title="Harm reduction">Harm reduction</a></li> <li><a href="/wiki/Health_economics" title="Health economics">Health economics</a></li> <li><a href="/wiki/Health_literacy" title="Health literacy">Health literacy</a></li> <li><a href="/wiki/Health_policy" title="Health policy">Health policy</a> <ul><li><a href="/wiki/Health_system" title="Health system">Health system</a></li> <li><a href="/wiki/Health_care_reform" title="Health care reform">Health care reform</a></li></ul></li> <li><a href="/wiki/Housing_First" title="Housing First">Housing First</a></li> <li><a href="/wiki/Human_right_to_water_and_sanitation" title="Human right to water and sanitation">Human right to water and sanitation</a></li> <li><a href="/wiki/Management_of_depression" title="Management of depression">Management of depression</a> <ul><li><a href="/wiki/Public_health_law" title="Public health law">Public health law</a></li> <li><a href="/wiki/National_public_health_institutes" class="mw-redirect" title="National public health institutes">National public health institute</a></li></ul></li> <li><a href="/wiki/Health_politics" title="Health politics">Health politics</a></li> <li><a href="/wiki/Labor_rights" title="Labor rights">Labor rights</a></li> <li><a href="/wiki/Maternal_health" title="Maternal health">Maternal health</a></li> <li><a href="/wiki/Medical_anthropology" title="Medical anthropology">Medical anthropology</a></li> <li><a href="/wiki/Medical_sociology" title="Medical sociology">Medical sociology</a></li> <li><a href="/wiki/Mental_health" title="Mental health">Mental health</a> (<a href="/wiki/Minister_of_Mental_Health" title="Minister of Mental Health">Ministers</a>)</li> <li><a href="/wiki/Occupational_safety_and_health" title="Occupational safety and health">Occupational safety and health</a></li> <li><a href="/wiki/Pharmaceutical_policy" title="Pharmaceutical policy">Pharmaceutical policy</a></li> <li><a href="/wiki/Pollution" title="Pollution">Pollution</a> <ul><li><a href="/wiki/Air_pollution" title="Air pollution">Air</a></li> <li><a href="/wiki/Water_pollution" title="Water pollution">Water</a></li> <li><a href="/wiki/Soil_pollution" class="mw-redirect" title="Soil pollution">Soil</a></li> <li><a href="/wiki/Radioactive_contamination" title="Radioactive contamination">Radiation</a></li> <li><a href="/wiki/Light_pollution" title="Light pollution">Light</a></li></ul></li> <li><a href="/wiki/Prisoners%27_rights" title="Prisoners' rights">Prisoners' rights</a></li> <li><a href="/wiki/Public_health_intervention" title="Public health intervention">Public health intervention</a></li> <li><a href="/wiki/Public_health_laboratory" title="Public health laboratory">Public health laboratory</a></li> <li><a href="/wiki/Right_to_food" title="Right to food">Right to food</a></li> <li><a href="/wiki/Right_to_health" title="Right to health">Right to health</a></li> <li><a href="/wiki/Right_to_a_healthy_environment" title="Right to a healthy environment">Right to a healthy environment</a></li> <li><a href="/wiki/Right_to_housing" title="Right to housing">Right to housing</a></li> <li><a href="/wiki/Right_to_rest_and_leisure" title="Right to rest and leisure">Right to rest and leisure</a></li> <li><a href="/wiki/Right_to_sit" title="Right to sit">Right to sit</a></li> <li><a href="/wiki/Security_of_person" title="Security of person">Security of person</a></li> <li><a href="/wiki/Sexual_and_reproductive_health" title="Sexual and reproductive health">Sexual and reproductive health</a></li> <li><a href="/wiki/Social_psychology" title="Social psychology">Social psychology</a></li> <li><a href="/wiki/Sociology_of_health_and_illness" title="Sociology of health and illness">Sociology of health and illness</a></li> <li><a href="/wiki/Unisex_changing_rooms" title="Unisex changing rooms">Unisex changing rooms</a></li> <li><a href="/wiki/Unisex_public_toilets" class="mw-redirect" title="Unisex public toilets">Unisex public toilets</a></li> <li><a href="/wiki/Workers%27_right_to_access_the_toilet" title="Workers' right to access the toilet">Workers' right to access the toilet</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Preventive_healthcare" title="Preventive healthcare">Preventive healthcare</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Behavior_change_(public_health)" title="Behavior change (public health)">Behavior change</a> <ul><li><a href="/wiki/Behavioural_change_theories" title="Behavioural change theories">Theories</a></li></ul></li> <li><a href="/wiki/Drug_checking" title="Drug checking">Drug checking</a></li> <li><a href="/wiki/Family_planning" title="Family planning">Family planning</a></li> <li><a href="/wiki/Harm_reduction" title="Harm reduction">Harm reduction</a></li> <li><a href="/wiki/Health_promotion" title="Health promotion">Health promotion</a></li> <li><a href="/wiki/Human_nutrition" title="Human nutrition">Human nutrition</a> <ul><li><a href="/wiki/Healthy_diet" title="Healthy diet">Healthy diet</a></li> <li><a href="/wiki/Preventive_nutrition" title="Preventive nutrition">Preventive nutrition</a></li></ul></li> <li><a href="/wiki/Hygiene" title="Hygiene">Hygiene</a> <ul><li><a href="/wiki/Food_safety" title="Food safety">Food safety</a></li> <li><a href="/wiki/Hand_washing" title="Hand washing">Hand washing</a></li> <li><a href="/wiki/Infection_control" class="mw-redirect" title="Infection control">Infection control</a></li> <li><a href="/wiki/Oral_hygiene" title="Oral hygiene">Oral hygiene</a></li></ul></li> <li><a href="/wiki/Needle_and_syringe_programmes" title="Needle and syringe programmes">Needle and syringe programmes</a></li> <li><a href="/wiki/Occupational_safety_and_health" title="Occupational safety and health">Occupational safety and health</a> <ul><li><a href="/wiki/Human_factors_and_ergonomics" class="mw-redirect" title="Human factors and ergonomics">Human factors and ergonomics</a></li> <li><a href="/wiki/Occupational_hygiene" title="Occupational hygiene">Hygiene</a></li> <li><a href="/wiki/Drug_policy" title="Drug policy">Controlled Drugs</a></li> <li><a href="/wiki/Injury_prevention" title="Injury prevention">Injury prevention</a></li> <li><a href="/wiki/Occupational_medicine" title="Occupational medicine">Medicine</a></li> <li><a href="/wiki/Occupational_health_nursing" title="Occupational health nursing">Nursing</a></li></ul></li> <li><a href="/wiki/Patient_safety" title="Patient safety">Patient safety</a> <ul><li><a href="/wiki/Patient_safety_organization" title="Patient safety organization">Organization</a></li></ul></li> <li><a href="/wiki/Pharmacovigilance" title="Pharmacovigilance">Pharmacovigilance</a></li> <li><a href="/wiki/Reagent_testing" title="Reagent testing">Reagent testing</a></li> <li><a href="/wiki/Safe_sex" title="Safe sex">Safe sex</a></li> <li><a href="/wiki/Sanitation" title="Sanitation">Sanitation</a> <ul><li><a href="/wiki/Emergency_sanitation" title="Emergency sanitation">Emergency</a></li> <li><a href="/wiki/Fecal%E2%80%93oral_route" title="Fecal–oral route">Fecal–oral transmission</a></li> <li><a href="/wiki/Open_defecation" title="Open defecation">Open defecation</a></li> <li><a href="/wiki/Sanitary_sewer" title="Sanitary sewer">Sanitary sewer</a></li> <li><a href="/wiki/Waterborne_diseases" class="mw-redirect" title="Waterborne diseases">Waterborne diseases</a></li> <li><a href="/wiki/Sanitation_worker" title="Sanitation worker">Worker</a></li></ul></li> <li><a href="/wiki/School_hygiene" title="School hygiene">School hygiene</a></li> <li><a href="/wiki/Smoking_cessation" title="Smoking cessation">Smoking cessation</a></li> <li><a href="/wiki/Supervised_injection_site" title="Supervised injection site">Supervised injection site</a></li> <li><a href="/wiki/Vaccination" title="Vaccination">Vaccination</a></li> <li><a href="/wiki/Vector_control" title="Vector control">Vector control</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Population_health" title="Population health">Population health</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Biostatistics" title="Biostatistics">Biostatistics</a></li> <li><a href="/wiki/Child_mortality" title="Child mortality">Child mortality</a></li> <li><a href="/wiki/Community_health" title="Community health">Community health</a></li> <li><a class="mw-selflink selflink">Epidemiology</a></li> <li><a href="/wiki/Global_health" title="Global health">Global health</a></li> <li><a href="/wiki/Health_impact_assessment" title="Health impact assessment">Health impact assessment</a></li> <li><a href="/wiki/Health_system" title="Health system">Health system</a></li> <li><a href="/wiki/Infant_mortality" title="Infant mortality">Infant mortality</a></li> <li><a href="/wiki/List_of_open-source_health_software" title="List of open-source health software">Open-source healthcare software</a></li> <li><a href="/wiki/Multimorbidity" title="Multimorbidity">Multimorbidity</a></li> <li><a href="/wiki/Public_health_informatics" title="Public health informatics">Public health informatics</a></li> <li><a href="/wiki/Social_determinants_of_health" title="Social determinants of health">Social determinants of health</a> <ul><li><a href="/wiki/Commercial_determinants_of_health" title="Commercial determinants of health">Commercial determinants of health</a></li> <li><a href="/wiki/Health_equity" title="Health equity">Health equity</a></li> <li><a href="/wiki/Race_and_health" title="Race and health">Race and health</a></li></ul></li> <li><a href="/wiki/Social_medicine" title="Social medicine">Social medicine</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Biological and<br />epidemiological statistics</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Case%E2%80%93control_study" title="Case–control study">Case–control study</a></li> <li><a href="/wiki/Randomized_controlled_trial" title="Randomized controlled trial">Randomized controlled trial</a></li> <li><a href="/wiki/Relative_risk" title="Relative risk">Relative risk</a></li> <li><a href="/wiki/Statistical_hypothesis_testing" class="mw-redirect" title="Statistical hypothesis testing">Statistical hypothesis testing</a> <ul><li><a href="/wiki/Analysis_of_variance" title="Analysis of variance">Analysis of variance (ANOVA)</a></li> <li><a href="/wiki/Regression_analysis" title="Regression analysis">Regression analysis</a></li> <li><a href="/wiki/ROC_curve" class="mw-redirect" title="ROC curve">ROC curve</a></li> <li><a href="/wiki/Student%27s_t-test" title="Student's t-test">Student's <i>t</i>-test</a></li> <li><a href="/wiki/Z-test" title="Z-test"><i>Z</i>-test</a></li></ul></li> <li><a href="/wiki/List_of_statistical_packages" class="mw-redirect" title="List of statistical packages">Statistical software</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Infectious and epidemic<br />disease prevention</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Asymptomatic_carrier" title="Asymptomatic carrier">Asymptomatic carrier</a></li> <li><a href="/wiki/Epidemic" title="Epidemic">Epidemics</a> <ul><li><a href="/wiki/List_of_epidemics_and_pandemics" title="List of epidemics and pandemics">List</a></li></ul></li> <li><a href="/wiki/Notifiable_disease" title="Notifiable disease">Notifiable diseases</a> <ul><li><a href="/wiki/List_of_notifiable_diseases" title="List of notifiable diseases">List</a></li></ul></li> <li><a href="/wiki/Public_health_surveillance" title="Public health surveillance">Public health surveillance</a> <ul><li><a href="/wiki/Disease_surveillance" title="Disease surveillance">Disease surveillance</a></li></ul></li> <li><a href="/wiki/Quarantine" title="Quarantine">Quarantine</a></li> <li><a href="/wiki/Sexually_transmitted_infection" title="Sexually transmitted infection">Sexually transmitted infection</a></li> <li><a href="/wiki/Social_distancing" title="Social distancing">Social distancing</a></li> <li><a href="/wiki/Tropical_disease" title="Tropical disease">Tropical disease</a></li> <li><a href="/wiki/Vaccine_trial" title="Vaccine trial">Vaccine trial</a></li> <li><a href="/wiki/WASH" title="WASH">WASH</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Food hygiene and<br />safety management</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>Food <ul><li><a href="/wiki/Food_additive" title="Food additive">Additive</a></li> <li><a href="/wiki/Food_chemistry" title="Food chemistry">Chemistry</a></li> <li><a href="/wiki/Food_engineering" title="Food engineering">Engineering</a></li> <li><a href="/wiki/Food_microbiology" title="Food microbiology">Microbiology</a></li> <li><a href="/wiki/Food_processing" title="Food processing">Processing</a></li> <li><a href="/wiki/Food_safety" title="Food safety">Safety</a></li> <li><a href="/wiki/Category:Food_safety_scandals" title="Category:Food safety scandals">Safety scandals</a></li></ul></li> <li><a href="/wiki/Good_agricultural_practice" title="Good agricultural practice">Good agricultural practice</a></li> <li><a href="/wiki/Good_manufacturing_practice" title="Good manufacturing practice">Good manufacturing practice</a> <ul><li><a href="/wiki/HACCP" class="mw-redirect" title="HACCP">HACCP</a></li> <li><a href="/wiki/ISO_22000" title="ISO 22000">ISO 22000</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Health behavioral<br />sciences</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Diffusion_of_innovations" title="Diffusion of innovations">Diffusion of innovations</a></li> <li><a href="/wiki/Health_belief_model" title="Health belief model">Health belief model</a></li> <li><a href="/wiki/Health_communication" title="Health communication">Health communication</a></li> <li><a href="/wiki/Health_psychology" title="Health psychology">Health psychology</a></li> <li><a href="/wiki/Positive_deviance" title="Positive deviance">Positive deviance</a></li> <li><a href="/wiki/PRECEDE%E2%80%93PROCEED_model" title="PRECEDE–PROCEED model">PRECEDE–PROCEED model</a></li> <li><a href="/wiki/Social_cognitive_theory" title="Social cognitive theory">Social cognitive theory</a></li> <li><a href="/wiki/Social_norms_approach" title="Social norms approach">Social norms approach</a></li> <li><a href="/wiki/Theory_of_planned_behavior" title="Theory of planned behavior">Theory of planned behavior</a></li> <li><a href="/wiki/Transtheoretical_model" title="Transtheoretical model">Transtheoretical model</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Organizations,<br />education<br />and history</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Organizations</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>Caribbean <ul><li><a href="/wiki/Caribbean_Public_Health_Agency" title="Caribbean Public Health Agency">Caribbean Public Health Agency</a></li></ul></li> <li>China <ul><li><a href="/wiki/Chinese_Center_for_Disease_Control_and_Prevention" title="Chinese Center for Disease Control and Prevention">Center for Disease Control and Prevention</a></li></ul></li> <li>Europe <ul><li><a href="/wiki/European_Centre_for_Disease_Prevention_and_Control" title="European Centre for Disease Prevention and Control">Centre for Disease Prevention and Control</a></li> <li><a href="/wiki/European_Parliament_Committee_on_the_Environment,_Public_Health_and_Food_Safety" title="European Parliament Committee on the Environment, Public Health and Food Safety">Committee on the Environment, Public Health and Food Safety</a></li></ul></li> <li>India <ul><li><a href="/wiki/Ministry_of_Health_and_Family_Welfare" title="Ministry of Health and Family Welfare">Ministry of Health and Family Welfare</a></li></ul></li> <li>Canada <ul><li><a href="/wiki/Health_Canada" title="Health Canada">Health Canada</a></li> <li><a href="/wiki/Public_Health_Agency_of_Canada" title="Public Health Agency of Canada">Public Health Agency</a></li></ul></li> <li>U.S. <ul><li><a href="/wiki/Centers_for_Disease_Control_and_Prevention" title="Centers for Disease Control and Prevention">Centers for Disease Control and Prevention</a></li> <li><a href="/wiki/Health_departments_in_the_United_States" title="Health departments in the United States">Health departments in the United States</a></li> <li><a href="/wiki/Council_on_Education_for_Public_Health" title="Council on Education for Public Health">Council on Education for Public Health</a></li> <li><a href="/wiki/United_States_Public_Health_Service" title="United States Public Health Service">Public Health Service</a></li></ul></li> <li><a href="/wiki/World_Health_Organization" title="World Health Organization">World Health Organization</a></li> <li><a href="/wiki/World_Toilet_Organization" title="World Toilet Organization">World Toilet Organization</a></li> <li>(<a href="/wiki/List_of_national_public_health_agencies" title="List of national public health agencies">Full list</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Education</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Health_education" title="Health education">Health education</a></li> <li>Higher education <ul><li><a href="/wiki/Bachelor_of_Science_in_Public_Health" title="Bachelor of Science in Public Health">Bachelor of Science in Public Health</a></li> <li><a href="/wiki/Doctor_of_Public_Health" title="Doctor of Public Health">Doctor of Public Health</a></li> <li><a href="/wiki/Professional_degrees_of_public_health" title="Professional degrees of public health">Professional degrees of public health</a></li> <li><a href="/wiki/Category:Schools_of_public_health" title="Category:Schools of public health">Schools of public health</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">History</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/History_of_public_health_in_the_United_Kingdom" title="History of public health in the United Kingdom">History of public health in the United Kingdom</a></li> <li><a href="/wiki/History_of_public_health_in_the_United_States" title="History of public health in the United States">History of public health in the United States</a></li> <li><a href="/wiki/Sara_Josephine_Baker" title="Sara Josephine Baker">Sara Josephine Baker</a></li> <li><a href="/wiki/Samuel_Jay_Crumbine" title="Samuel Jay Crumbine">Samuel Jay Crumbine</a></li> <li><a href="/wiki/Carl_Rogers_Darnall" title="Carl Rogers Darnall">Carl Rogers Darnall</a></li> <li><a href="/wiki/Joseph_Lister" title="Joseph Lister">Joseph Lister</a></li> <li><a href="/wiki/Margaret_Sanger" title="Margaret Sanger">Margaret Sanger</a></li> <li><a href="/wiki/John_Snow_(physician)" class="mw-redirect" title="John Snow (physician)">John Snow</a></li> <li><a href="/wiki/Mary_Mallon" title="Mary Mallon">Typhoid Mary</a></li> <li><a href="/wiki/Radium_Girls" title="Radium Girls">Radium Girls</a></li> <li><a href="/wiki/Germ_theory_of_disease" title="Germ theory of disease">Germ theory of disease</a></li> <li><a href="/wiki/Social_hygiene_movement" title="Social hygiene movement">Social hygiene movement</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <ul><li><span class="noviewer" typeof="mw:File"><span title="Category"><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/16px-Symbol_category_class.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/23px-Symbol_category_class.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/31px-Symbol_category_class.svg.png 2x" data-file-width="180" data-file-height="185" /></span></span> <b><a href="/wiki/Category:Public_health" title="Category:Public health">Category</a></b></li> <li><span class="noviewer" typeof="mw:File"><span title="Commons page"><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/12px-Commons-logo.svg.png" decoding="async" width="12" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/18px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/24px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></span></span> <b><a href="https://commons.wikimedia.org/wiki/Category:Public_health" class="extiw" title="commons:Category:Public health">Commons</a></b></li> <li><span class="noviewer" typeof="mw:File"><span title="WikiProject"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/37/People_icon.svg/16px-People_icon.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/37/People_icon.svg/24px-People_icon.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/37/People_icon.svg/32px-People_icon.svg.png 2x" data-file-width="100" data-file-height="100" /></span></span> <b><a href="/wiki/Wikipedia:WikiProject_Nursing" title="Wikipedia:WikiProject Nursing">WikiProject</a></b></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Branches_of_biology59" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Branches_of_biology" title="Template:Branches of biology"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Branches_of_biology" title="Template talk:Branches of biology"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Branches_of_biology" title="Special:EditPage/Template:Branches of biology"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Branches_of_biology59" style="font-size:114%;margin:0 4em"><a href="/wiki/Outline_of_biology#Branches" title="Outline of biology">Branches of biology</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abiogenesis" title="Abiogenesis">Abiogenesis</a></li> <li><a href="/wiki/Aerobiology" title="Aerobiology">Aerobiology</a></li> <li><a href="/wiki/Agronomy" title="Agronomy">Agronomy</a></li> <li><a href="/wiki/Agrostology" title="Agrostology">Agrostology</a></li> <li><a href="/wiki/Anatomy" title="Anatomy">Anatomy</a></li> <li><a href="/wiki/Astrobiology" title="Astrobiology">Astrobiology</a></li> <li><a href="/wiki/Bacteriology" title="Bacteriology">Bacteriology</a></li> <li><a href="/wiki/Biochemistry" title="Biochemistry">Biochemistry</a></li> <li><a href="/wiki/Biogeography" title="Biogeography">Biogeography</a></li> <li><a href="/wiki/Biogeology" title="Biogeology">Biogeology</a></li> <li><a href="/wiki/Bioinformatics" title="Bioinformatics">Bioinformatics</a></li> <li><a href="/wiki/Biological_engineering" title="Biological engineering">Biological engineering</a></li> <li><a href="/wiki/Biomechanics" title="Biomechanics">Biomechanics</a></li> <li><a href="/wiki/Biophysics" title="Biophysics">Biophysics</a></li> <li><a href="/wiki/Biosemiotics" title="Biosemiotics">Biosemiotics</a></li> <li><a href="/wiki/Biostatistics" title="Biostatistics">Biostatistics</a></li> <li><a href="/wiki/Biotechnology" title="Biotechnology">Biotechnology</a></li> <li><a href="/wiki/Botany" title="Botany">Botany</a></li> <li><a href="/wiki/Cell_biology" title="Cell biology">Cell biology</a></li> <li><a href="/wiki/Cellular_microbiology" title="Cellular microbiology">Cellular microbiology</a></li> <li><a href="/wiki/Chemical_biology" title="Chemical biology">Chemical biology</a></li> <li><a href="/wiki/Chronobiology" title="Chronobiology">Chronobiology</a></li> <li><a href="/wiki/Cognitive_biology" title="Cognitive biology">Cognitive biology</a></li> <li><a href="/wiki/Computational_biology" title="Computational biology">Computational biology</a></li> <li><a href="/wiki/Conservation_biology" title="Conservation biology">Conservation biology</a></li> <li><a href="/wiki/Cryobiology" title="Cryobiology">Cryobiology</a></li> <li><a href="/wiki/Cytogenetics" title="Cytogenetics">Cytogenetics</a></li> <li><a href="/wiki/Dendrology" title="Dendrology">Dendrology</a></li> <li><a href="/wiki/Developmental_biology" title="Developmental biology">Developmental biology</a></li> <li><a href="/wiki/Ecological_genetics" title="Ecological genetics">Ecological genetics</a></li> <li><a href="/wiki/Ecology" title="Ecology">Ecology</a></li> <li><a href="/wiki/Embryology" title="Embryology">Embryology</a></li> <li><a class="mw-selflink selflink">Epidemiology</a></li> <li><a href="/wiki/Epigenetics" title="Epigenetics">Epigenetics</a></li> <li><a href="/wiki/Evolutionary_biology" title="Evolutionary biology">Evolutionary biology</a></li> <li><a href="/wiki/Freshwater_biology" title="Freshwater biology">Freshwater biology</a></li> <li><a href="/wiki/Generative_biology" class="mw-redirect" title="Generative biology">Generative biology</a></li> <li><a href="/wiki/Genetics" title="Genetics">Genetics</a></li> <li><a href="/wiki/Genomics" title="Genomics">Genomics</a></li> <li><a href="/wiki/Geobiology" title="Geobiology">Geobiology</a></li> <li><a href="/wiki/Gerontology" title="Gerontology">Gerontology</a></li> <li><a href="/wiki/Herpetology" title="Herpetology">Herpetology</a></li> <li><a href="/wiki/Histology" title="Histology">Histology</a></li> <li><a href="/wiki/Human_biology" title="Human biology">Human biology</a></li> <li><a href="/wiki/Ichthyology" title="Ichthyology">Ichthyology</a></li> <li><a href="/wiki/Immunology" title="Immunology">Immunology</a></li> <li><a href="/wiki/Lipidology" title="Lipidology">Lipidology</a></li> <li><a href="/wiki/Mammalogy" title="Mammalogy">Mammalogy</a></li> <li><a href="/wiki/Marine_biology" title="Marine biology">Marine biology</a></li> <li><a href="/wiki/Mathematical_and_theoretical_biology" title="Mathematical and theoretical biology">Mathematical biology</a></li> <li><a href="/wiki/Microbiology" title="Microbiology">Microbiology</a></li> <li><a href="/wiki/Molecular_biology" title="Molecular biology">Molecular biology</a></li> <li><a href="/wiki/Mycology" title="Mycology">Mycology</a></li> <li><a href="/wiki/Neontology" title="Neontology">Neontology</a></li> <li><a href="/wiki/Neuroscience" title="Neuroscience">Neuroscience</a></li> <li><a href="/wiki/Nutritional_science" title="Nutritional science">Nutrition</a></li> <li><a href="/wiki/Ornithology" title="Ornithology">Ornithology</a></li> <li><a href="/wiki/Osteology" title="Osteology">Osteology</a></li> <li><a href="/wiki/Paleontology" title="Paleontology">Paleontology</a></li> <li><a href="/wiki/Parasitology" title="Parasitology">Parasitology</a></li> <li><a href="/wiki/Pathology" title="Pathology">Pathology</a></li> <li><a href="/wiki/Pharmacology" title="Pharmacology">Pharmacology</a></li> <li><a href="/wiki/Photobiology" title="Photobiology">Photobiology</a></li> <li><a href="/wiki/Phycology" title="Phycology">Phycology</a></li> <li><a href="/wiki/Phylogenetics" title="Phylogenetics">Phylogenetics</a></li> <li><a href="/wiki/Physiology" title="Physiology">Physiology</a></li> <li><a href="/wiki/Pomology" title="Pomology">Pomology</a></li> <li><a href="/wiki/Primatology" title="Primatology">Primatology</a></li> <li><a href="/wiki/Proteomics" title="Proteomics">Proteomics</a></li> <li><a href="/wiki/Protistology" title="Protistology">Protistology</a></li> <li><a href="/wiki/Quantum_biology" title="Quantum biology">Quantum biology</a></li> <li><a href="/wiki/Relational_biology" class="mw-redirect" title="Relational biology">Relational biology</a></li> <li><a href="/wiki/Reproductive_biology" title="Reproductive biology">Reproductive biology</a></li> <li><a href="/wiki/Sociobiology" title="Sociobiology">Sociobiology</a></li> <li><a href="/wiki/Structural_biology" title="Structural biology">Structural biology</a></li> <li><a href="/wiki/Synthetic_biology" title="Synthetic biology">Synthetic biology</a></li> <li><a href="/wiki/Systematics" title="Systematics">Systematics</a></li> <li><a href="/wiki/Systems_biology" title="Systems biology">Systems biology</a></li> <li><a href="/wiki/Taxonomy_(biology)" title="Taxonomy (biology)">Taxonomy</a></li> <li><a href="/wiki/Teratology" title="Teratology">Teratology</a></li> <li><a href="/wiki/Toxicology" title="Toxicology">Toxicology</a></li> <li><a href="/wiki/Virology" title="Virology">Virology</a></li> <li><a href="/wiki/Virophysics" title="Virophysics">Virophysics</a></li> <li><a href="/wiki/Xenobiology" title="Xenobiology">Xenobiology</a></li> <li><a href="/wiki/Zoology" title="Zoology">Zoology</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">See also</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/History_of_biology" title="History of biology">History of biology</a></li> <li><a href="/wiki/Nobel_Prize_in_Physiology_or_Medicine" title="Nobel Prize in Physiology or Medicine">Nobel Prize in Physiology or Medicine</a></li> <li><a href="/wiki/Timeline_of_biology_and_organic_chemistry" title="Timeline of biology and organic chemistry">Timeline of biology and organic chemistry</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"><style data-mw-deduplicate="TemplateStyles:r1066933788">.mw-parser-output .excerpt-hat .mw-editsection-like{font-style:normal}</style></div><div role="navigation" class="navbox" aria-labelledby="Biology858" style="padding:3px"><table class="nowraplinks hlist mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="3"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Biology_nav" title="Template:Biology nav"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Biology_nav" title="Template talk:Biology nav"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Biology_nav" title="Special:EditPage/Template:Biology nav"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Biology858" style="font-size:114%;margin:0 4em"><a href="/wiki/Biology" title="Biology">Biology</a></div></th></tr><tr><td class="navbox-abovebelow" colspan="3"><div> <ul><li>Introduction (<a href="/wiki/Introduction_to_genetics" title="Introduction to genetics">Genetics</a>, <a href="/wiki/Introduction_to_evolution" title="Introduction to evolution">Evolution</a>)</li> <li><a href="/wiki/Outline_of_biology" title="Outline of biology">Outline</a></li> <li><a href="/wiki/History_of_biology" title="History of biology">History</a> <ul><li><a href="/wiki/Timeline_of_biology_and_organic_chemistry" title="Timeline of biology and organic chemistry">Timeline</a></li></ul></li> <li><a href="/wiki/Index_of_biology_articles" title="Index of biology articles">Index</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Biology" title="Biology">Biology</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Overview</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Science" title="Science">Science</a></li> <li><a href="/wiki/Life" title="Life">Life</a></li> <li>Properties (<a href="/wiki/Adaptation" title="Adaptation">Adaptation</a>, <a href="/wiki/Metabolism" title="Metabolism"> Energy processing</a>, <a href="/wiki/Developmental_biology" title="Developmental biology">Growth</a>, <a href="/wiki/Structure#Biological" title="Structure">Order</a>, <a href="/wiki/Homeostasis" title="Homeostasis">Regulation</a>, <a href="/wiki/Reproduction" title="Reproduction">Reproduction</a> (<a href="/wiki/Self-replication" title="Self-replication">Self-replication</a>), <a href="/wiki/Stimulus_(physiology)" title="Stimulus (physiology)">Response to environment</a>)</li> <li><a href="/wiki/Biological_organisation" title="Biological organisation">Hierarchy of life</a> (<a href="/wiki/Atom" title="Atom">Atom</a> > <a href="/wiki/Molecule" title="Molecule">Molecule</a> > <a href="/wiki/Organelle" title="Organelle">Organelle</a> > <a href="/wiki/Cell_(biology)" title="Cell (biology)">Cell</a> > <a href="/wiki/Tissue_(biology)" title="Tissue (biology)">Tissue</a> > <a href="/wiki/Organ_(biology)" title="Organ (biology)">Organ</a> > <a href="/wiki/Biological_system" title="Biological system">Organ system</a> > <a href="/wiki/Organism" title="Organism">Organism</a> > <a href="/wiki/Population" title="Population">Population</a> > <a href="/wiki/Biocoenosis" title="Biocoenosis">Community</a> > <a href="/wiki/Ecosystem" title="Ecosystem">Ecosystem</a> > <a href="/wiki/Biosphere" title="Biosphere">Biosphere</a>)</li> <li><a href="/wiki/Reductionism#In_science" title="Reductionism">Reductionistic</a></li> <li><a href="/wiki/Emergence" title="Emergence"> Emergent property</a></li> <li><a href="/wiki/Mechanical_philosophy" class="mw-redirect" title="Mechanical philosophy">Mechanistic</a></li> <li><a href="/wiki/Scientific_method" title="Scientific method">Scientific method</a></li> <li><a href="/wiki/Taxonomic_rank" title="Taxonomic rank">Taxonomic rank</a></li> <li><a href="/wiki/Scientific_theory" title="Scientific theory"> Theory</a></li> <li><a href="/wiki/Scientific_law" title="Scientific law"> Law</a></li> <li><a href="/wiki/Peer_review" title="Peer review">Peer review</a></li> <li><a href="/wiki/List_of_biology_journals" title="List of biology journals">Biology journals</a></li> <li><a href="/wiki/Common_name" title="Common name">Common name</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Chemical basis</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Atom" title="Atom">Atoms</a></li> <li><a href="/wiki/Amino_acid" title="Amino acid">Amino acids</a></li> <li><a href="/wiki/Carbohydrate" title="Carbohydrate">Carbohydrates</a></li> <li><a href="/wiki/Chemical_bond" title="Chemical bond">Chemical bond</a></li> <li><a href="/wiki/Chemical_element" title="Chemical element">Chemical element</a></li> <li><a href="/wiki/Lipid" title="Lipid">Lipids</a></li> <li><a href="/wiki/Matter" title="Matter">Matter</a> <ul><li><a href="/wiki/Quantum_biology" title="Quantum biology">Quantum</a></li></ul></li> <li><a href="/wiki/Molecule" title="Molecule">Molecules</a></li> <li><a href="/wiki/Monomer" title="Monomer">Monomer</a></li> <li><a href="/wiki/Nucleic_acid" title="Nucleic acid">Nucleic acids</a></li> <li><a href="/wiki/Organic_compound" title="Organic compound">Organic compounds</a></li> <li><a href="/wiki/PH" title="PH">pH</a></li> <li><a href="/wiki/Polymer" title="Polymer">Polymer</a></li> <li><a href="/wiki/Protein" title="Protein">Proteins</a></li> <li><a href="/wiki/Water" title="Water">Water</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cell_(biology)" title="Cell (biology)">Cells</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Adenosine_triphosphate" title="Adenosine triphosphate">ATP</a></li> <li><a href="/wiki/Cell_cycle" title="Cell cycle">Cell cycle</a></li> <li><a href="/wiki/Cell_theory" title="Cell theory">Cell theory</a></li> <li><a href="/wiki/Cell_signaling" title="Cell signaling">Cell signaling</a></li> <li><a href="/wiki/Cellular_respiration" title="Cellular respiration">Cellular respiration</a></li> <li><a href="/wiki/Energy" title="Energy">Energy transformation</a></li> <li><a href="/wiki/Enzyme" title="Enzyme">Enzyme</a></li> <li><a href="/wiki/Eukaryote" title="Eukaryote">Eukaryote</a></li> <li><a href="/wiki/Fermentation" title="Fermentation">Fermentation</a></li> <li><a href="/wiki/Metabolism" title="Metabolism">Metabolism</a></li> <li><a href="/wiki/Meiosis" title="Meiosis">Meiosis</a></li> <li><a href="/wiki/Mitosis" title="Mitosis">Mitosis</a></li> <li><a href="/wiki/Photosynthesis" title="Photosynthesis">Photosynthesis</a></li> <li><a href="/wiki/Prokaryote" title="Prokaryote">Prokaryote</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Genetics" title="Genetics">Genetics</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/DNA" title="DNA">DNA</a></li> <li><a href="/wiki/Epigenetics" title="Epigenetics">Epigenetics</a></li> <li><a href="/wiki/Evolutionary_developmental_biology" title="Evolutionary developmental biology">Evolutionary developmental biology</a></li> <li><a href="/wiki/Gene_expression" title="Gene expression">Gene expression</a></li> <li><a href="/wiki/Regulation_of_gene_expression" title="Regulation of gene expression">Gene regulation</a></li> <li><a href="/wiki/Genome" title="Genome">Genomes</a></li> <li><a href="/wiki/Mendelian_inheritance" title="Mendelian inheritance">Mendelian inheritance</a></li> <li><a href="/wiki/Post-transcriptional_modification" title="Post-transcriptional modification">Post-transcriptional modification</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Evolution" title="Evolution">Evolution</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Adaptation" title="Adaptation">Adaptation</a></li> <li><a href="/wiki/Earliest_known_life_forms" title="Earliest known life forms">Earliest known life forms</a></li> <li><a href="/wiki/Function_(biology)" title="Function (biology)">Function</a></li> <li><a href="/wiki/Genetic_drift" title="Genetic drift">Genetic drift</a></li> <li><a href="/wiki/Gene_flow" title="Gene flow">Gene flow</a></li> <li><a href="/wiki/History_of_life" title="History of life">History of life</a></li> <li><a href="/wiki/Macroevolution" title="Macroevolution">Macroevolution</a></li> <li><a href="/wiki/Microevolution" title="Microevolution">Microevolution</a></li> <li><a href="/wiki/Mutation" title="Mutation">Mutation</a></li> <li><a href="/wiki/Natural_selection" title="Natural selection">Natural selection</a></li> <li><a href="/wiki/Phylogenetics" title="Phylogenetics">Phylogenetics</a></li> <li><a href="/wiki/Speciation" title="Speciation">Speciation</a></li> <li><a href="/wiki/Taxonomy_(biology)" title="Taxonomy (biology)">Taxonomy</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Biodiversity" title="Biodiversity">Diversity</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Archaea" title="Archaea">Archaea</a></li> <li><a href="/wiki/Bacteria" title="Bacteria">Bacteria</a></li> <li><a href="/wiki/Eukaryote" title="Eukaryote">Eukaryote</a> <ul><li><a href="/wiki/Alga" class="mw-redirect" title="Alga">Alga</a></li> <li><a href="/wiki/Animal" title="Animal">Animal</a></li> <li><a href="/wiki/Fungus" title="Fungus">Fungus</a></li> <li><a href="/wiki/Plant" title="Plant">Plant</a></li> <li><a href="/wiki/Protist" title="Protist">Protist</a></li></ul></li> <li><a href="/wiki/Virus" title="Virus">Virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Plant form <br /> and function</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Epidermis_(botany)" title="Epidermis (botany)">Epidermis (botany)</a></li> <li><a href="/wiki/Flower" title="Flower">Flower</a></li> <li><a href="/wiki/Ground_tissue" title="Ground tissue">Ground tissue</a></li> <li><a href="/wiki/Leaf" title="Leaf">Leaf</a></li> <li><a href="/wiki/Phloem" title="Phloem">Phloem</a></li> <li><a href="/wiki/Plant_stem" title="Plant stem">Plant stem</a></li> <li><a href="/wiki/Root" title="Root">Root</a></li> <li><a href="/wiki/Shoot_(botany)" title="Shoot (botany)">Shoot</a></li> <li><a href="/wiki/Vascular_plant" title="Vascular plant">Vascular plant</a></li> <li><a href="/wiki/Vascular_tissue" title="Vascular tissue">Vascular tissue</a></li> <li><a href="/wiki/Xylem" title="Xylem">Xylem</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Animal form <br />and function</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Breathing" title="Breathing">Breathing</a></li> <li><a href="/wiki/Circulatory_system" title="Circulatory system">Circulatory system</a></li> <li><a href="/wiki/Endocrine_system" title="Endocrine system">Endocrine system</a></li> <li><a href="/wiki/Human_digestive_system" title="Human digestive system">Digestive system</a></li> <li><a href="/wiki/Homeostasis" title="Homeostasis">Homeostasis</a></li> <li><a href="/wiki/Immune_system" title="Immune system">Immune system</a></li> <li><a href="/wiki/Internal_environment" title="Internal environment">Internal environment</a></li> <li><a href="/wiki/Muscular_system" title="Muscular system">Muscular system</a></li> <li><a href="/wiki/Nervous_system" title="Nervous system">Nervous system</a></li> <li><a href="/wiki/Reproductive_system" title="Reproductive system">Reproductive system</a></li> <li><a href="/wiki/Respiratory_system" title="Respiratory system">Respiratory system</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Ecology" title="Ecology">Ecology</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Biogeochemical_cycle" title="Biogeochemical cycle">Biogeochemical cycle</a></li> <li><a href="/wiki/Biological_interaction" title="Biological interaction">Biological interaction</a></li> <li><a href="/wiki/Biomass" title="Biomass">Biomass</a></li> <li><a href="/wiki/Biome" title="Biome">Biomes</a></li> <li><a href="/wiki/Biosphere" title="Biosphere">Biosphere</a></li> <li><a href="/wiki/Climate" title="Climate">Climate</a></li> <li><a href="/wiki/Climate_change" title="Climate change">Climate change</a></li> <li><a href="/wiki/Community_(ecology)" title="Community (ecology)">Community</a></li> <li><a href="/wiki/Conservation_biology" title="Conservation biology">Conservation</a></li> <li><a href="/wiki/Ecosystem_ecology" title="Ecosystem ecology">Ecosystem</a></li> <li><a href="/wiki/Habitat" title="Habitat">Habitat</a> <ul><li><a href="/wiki/Ecological_niche" title="Ecological niche">niche</a></li></ul></li> <li><a href="/wiki/Microbiome" title="Microbiome">Microbiome</a></li> <li><a href="/wiki/Population_ecology" title="Population ecology">Population dynamics</a></li> <li><a href="/wiki/Resource_(biology)" title="Resource (biology)">Resources</a></li></ul> </div></td></tr></tbody></table><div></div></td><td class="noviewer navbox-image" rowspan="4" style="width:1px;padding:0 0 0 2px"><div><span typeof="mw:File"><a href="/wiki/File:Tree_of_life_by_Haeckel.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/de/Tree_of_life_by_Haeckel.jpg/140px-Tree_of_life_by_Haeckel.jpg" decoding="async" width="140" height="222" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/de/Tree_of_life_by_Haeckel.jpg/210px-Tree_of_life_by_Haeckel.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/de/Tree_of_life_by_Haeckel.jpg/280px-Tree_of_life_by_Haeckel.jpg 2x" data-file-width="1804" data-file-height="2856" /></a></span></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/List_of_research_methods_in_biology" title="List of research methods in biology">Research <br /> methods</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Laboratory <br /> techniques</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Genetic_engineering" title="Genetic engineering">Genetic engineering</a></li> <li><a href="/wiki/Transformation_(genetics)" class="mw-redirect" title="Transformation (genetics)">Transformation</a></li> <li><a href="/wiki/Gel_electrophoresis" title="Gel electrophoresis">Gel electrophoresis</a></li> <li><a href="/wiki/Chromatography" title="Chromatography">Chromatography</a></li> <li><a href="/wiki/Centrifugation" title="Centrifugation">Centrifugation</a></li> <li><a href="/wiki/Cell_culture" title="Cell culture">Cell culture</a></li> <li><a href="/wiki/DNA_sequencing" title="DNA sequencing">DNA sequencing</a></li> <li><a href="/wiki/DNA_microarray" title="DNA microarray">DNA microarray</a></li> <li><a href="/wiki/Green_fluorescent_protein" title="Green fluorescent protein">Green fluorescent protein</a></li> <li><a href="/wiki/Vector_(molecular_biology)" title="Vector (molecular biology)">vector</a></li> <li><a href="/wiki/Enzyme_assay" title="Enzyme assay">Enzyme assay</a></li> <li><a href="/wiki/Protein_purification" title="Protein purification">Protein purification</a></li> <li><a href="/wiki/Western_blot" title="Western blot">Western blot</a></li> <li><a href="/wiki/Northern_blot" title="Northern blot">Northern blot</a></li> <li><a href="/wiki/Southern_blot" title="Southern blot">Southern blot</a></li> <li><a href="/wiki/Restriction_enzyme" title="Restriction enzyme">Restriction enzyme</a></li> <li><a href="/wiki/Polymerase_chain_reaction" title="Polymerase chain reaction">Polymerase chain reaction</a></li> <li><a href="/wiki/Two-hybrid_screening" title="Two-hybrid screening">Two-hybrid screening</a></li> <li><i><a href="/wiki/In_vivo" title="In vivo">in vivo</a></i></li> <li><i><a href="/wiki/In_vitro" title="In vitro">in vitro</a></i></li> <li><i><a href="/wiki/In_silico" title="In silico">in silico</a></i></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Field techniques</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Belt_transect" title="Belt transect">Belt transect</a></li> <li><a href="/wiki/Mark_and_recapture" title="Mark and recapture">mark and recapture</a></li> <li><a href="/wiki/Species_discovery_curve" title="Species discovery curve">species discovery curve</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Branches</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><div class="excerpt-block"><div class="excerpt"> <ul><li><a href="/wiki/Abiogenesis" title="Abiogenesis">Abiogenesis</a></li> <li><a href="/wiki/Aerobiology" title="Aerobiology">Aerobiology</a></li> <li><a href="/wiki/Agronomy" title="Agronomy">Agronomy</a></li> <li><a href="/wiki/Agrostology" title="Agrostology">Agrostology</a></li> <li><a href="/wiki/Anatomy" title="Anatomy">Anatomy</a></li> <li><a href="/wiki/Astrobiology" title="Astrobiology">Astrobiology</a></li> <li><a href="/wiki/Bacteriology" title="Bacteriology">Bacteriology</a></li> <li><a href="/wiki/Biochemistry" title="Biochemistry">Biochemistry</a></li> <li><a href="/wiki/Biogeography" title="Biogeography">Biogeography</a></li> <li><a href="/wiki/Biogeology" title="Biogeology">Biogeology</a></li> <li><a href="/wiki/Bioinformatics" title="Bioinformatics">Bioinformatics</a></li> <li><a href="/wiki/Biological_engineering" title="Biological engineering">Biological engineering</a></li> <li><a href="/wiki/Biomechanics" title="Biomechanics">Biomechanics</a></li> <li><a href="/wiki/Biophysics" title="Biophysics">Biophysics</a></li> <li><a href="/wiki/Biosemiotics" title="Biosemiotics">Biosemiotics</a></li> <li><a href="/wiki/Biostatistics" title="Biostatistics">Biostatistics</a></li> <li><a href="/wiki/Biotechnology" title="Biotechnology">Biotechnology</a></li> <li><a href="/wiki/Botany" title="Botany">Botany</a></li> <li><a href="/wiki/Cell_biology" title="Cell biology">Cell biology</a></li> <li><a href="/wiki/Cellular_microbiology" title="Cellular microbiology">Cellular microbiology</a></li> <li><a href="/wiki/Chemical_biology" title="Chemical biology">Chemical biology</a></li> <li><a href="/wiki/Chronobiology" title="Chronobiology">Chronobiology</a></li> <li><a href="/wiki/Cognitive_biology" title="Cognitive biology">Cognitive biology</a></li> <li><a href="/wiki/Computational_biology" title="Computational biology">Computational biology</a></li> <li><a href="/wiki/Conservation_biology" title="Conservation biology">Conservation biology</a></li> <li><a href="/wiki/Cryobiology" title="Cryobiology">Cryobiology</a></li> <li><a href="/wiki/Cytogenetics" title="Cytogenetics">Cytogenetics</a></li> <li><a href="/wiki/Dendrology" title="Dendrology">Dendrology</a></li> <li><a href="/wiki/Developmental_biology" title="Developmental biology">Developmental biology</a></li> <li><a href="/wiki/Ecological_genetics" title="Ecological genetics">Ecological genetics</a></li> <li><a href="/wiki/Ecology" title="Ecology">Ecology</a></li> <li><a href="/wiki/Embryology" title="Embryology">Embryology</a></li> <li>Epidemiology</li> <li><a href="/wiki/Epigenetics" title="Epigenetics">Epigenetics</a></li> <li><a href="/wiki/Evolutionary_biology" title="Evolutionary biology">Evolutionary biology</a></li> <li><a href="/wiki/Freshwater_biology" title="Freshwater biology">Freshwater biology</a></li> <li><a href="/wiki/Generative_biology" class="mw-redirect" title="Generative biology">Generative biology</a></li> <li><a href="/wiki/Genetics" title="Genetics">Genetics</a></li> <li><a href="/wiki/Genomics" title="Genomics">Genomics</a></li> <li><a href="/wiki/Geobiology" title="Geobiology">Geobiology</a></li> <li><a href="/wiki/Gerontology" title="Gerontology">Gerontology</a></li> <li><a href="/wiki/Herpetology" title="Herpetology">Herpetology</a></li> <li><a href="/wiki/Histology" title="Histology">Histology</a></li> <li><a href="/wiki/Human_biology" title="Human biology">Human biology</a></li> <li><a href="/wiki/Ichthyology" title="Ichthyology">Ichthyology</a></li> <li><a href="/wiki/Immunology" title="Immunology">Immunology</a></li> <li><a href="/wiki/Lipidology" title="Lipidology">Lipidology</a></li> <li><a href="/wiki/Mammalogy" title="Mammalogy">Mammalogy</a></li> <li><a href="/wiki/Marine_biology" title="Marine biology">Marine biology</a></li> <li><a href="/wiki/Mathematical_and_theoretical_biology" title="Mathematical and theoretical biology">Mathematical biology</a></li> <li><a href="/wiki/Microbiology" title="Microbiology">Microbiology</a></li> <li><a href="/wiki/Molecular_biology" title="Molecular biology">Molecular biology</a></li> <li><a href="/wiki/Mycology" title="Mycology">Mycology</a></li> <li><a href="/wiki/Neontology" title="Neontology">Neontology</a></li> <li><a href="/wiki/Neuroscience" title="Neuroscience">Neuroscience</a></li> <li><a href="/wiki/Nutritional_science" title="Nutritional science">Nutrition</a></li> <li><a href="/wiki/Ornithology" title="Ornithology">Ornithology</a></li> <li><a href="/wiki/Osteology" title="Osteology">Osteology</a></li> <li><a href="/wiki/Paleontology" title="Paleontology">Paleontology</a></li> <li><a href="/wiki/Parasitology" title="Parasitology">Parasitology</a></li> <li><a href="/wiki/Pathology" title="Pathology">Pathology</a></li> <li><a href="/wiki/Pharmacology" title="Pharmacology">Pharmacology</a></li> <li><a href="/wiki/Photobiology" title="Photobiology">Photobiology</a></li> <li><a href="/wiki/Phycology" title="Phycology">Phycology</a></li> <li><a href="/wiki/Phylogenetics" title="Phylogenetics">Phylogenetics</a></li> <li><a href="/wiki/Physiology" title="Physiology">Physiology</a></li> <li><a href="/wiki/Pomology" title="Pomology">Pomology</a></li> <li><a href="/wiki/Primatology" title="Primatology">Primatology</a></li> <li><a href="/wiki/Proteomics" title="Proteomics">Proteomics</a></li> <li><a href="/wiki/Protistology" title="Protistology">Protistology</a></li> <li><a href="/wiki/Quantum_biology" title="Quantum biology">Quantum biology</a></li> <li><a href="/wiki/Relational_biology" class="mw-redirect" title="Relational biology">Relational biology</a></li> <li><a href="/wiki/Reproductive_biology" title="Reproductive biology">Reproductive biology</a></li> <li><a href="/wiki/Sociobiology" title="Sociobiology">Sociobiology</a></li> <li><a href="/wiki/Structural_biology" title="Structural biology">Structural biology</a></li> <li><a href="/wiki/Synthetic_biology" title="Synthetic biology">Synthetic biology</a></li> <li><a href="/wiki/Systematics" title="Systematics">Systematics</a></li> <li><a href="/wiki/Systems_biology" title="Systems biology">Systems biology</a></li> <li><a href="/wiki/Taxonomy_(biology)" title="Taxonomy (biology)">Taxonomy</a></li> <li><a href="/wiki/Teratology" title="Teratology">Teratology</a></li> <li><a href="/wiki/Toxicology" title="Toxicology">Toxicology</a></li> <li><a href="/wiki/Virology" title="Virology">Virology</a></li> <li><a href="/wiki/Virophysics" title="Virophysics">Virophysics</a></li> <li><a href="/wiki/Xenobiology" title="Xenobiology">Xenobiology</a></li> <li><a href="/wiki/Zoology" title="Zoology">Zoology</a></li></ul></div></div> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Glossaries</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Glossary_of_biology" title="Glossary of biology">Biology</a></li> <li><a href="/wiki/Glossary_of_botanical_terms" title="Glossary of botanical terms">Botanical terms</a></li> <li><a href="/wiki/Glossary_of_ecology" title="Glossary of ecology">Ecological terms</a></li> <li><a href="/wiki/Glossary_of_plant_morphology" title="Glossary of plant morphology">Plant morphology terms</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="3"><div> <ul><li><span class="nowrap"><span class="nowrap"><span class="noviewer" typeof="mw:File"><a href="/wiki/File:Issoria_lathonia.jpg" class="mw-file-description"><img alt="icon" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Issoria_lathonia.jpg/16px-Issoria_lathonia.jpg" decoding="async" width="16" height="11" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Issoria_lathonia.jpg/24px-Issoria_lathonia.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Issoria_lathonia.jpg/32px-Issoria_lathonia.jpg 2x" data-file-width="629" data-file-height="445" /></a></span> </span><a href="/wiki/Portal:Biology" title="Portal:Biology">Biology portal</a></span></li> <li><span class="noviewer" typeof="mw:File"><span title="Category"><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/16px-Symbol_category_class.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/23px-Symbol_category_class.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/31px-Symbol_category_class.svg.png 2x" data-file-width="180" data-file-height="185" /></span></span> <a href="/wiki/Category:Biology" title="Category:Biology">Category</a></li> <li><span class="noviewer" typeof="mw:File"><span title="Commons page"><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/12px-Commons-logo.svg.png" decoding="async" width="12" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/18px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/24px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></span></span> <a href="https://commons.wikimedia.org/wiki/Category:Biology" class="extiw" title="commons:Category:Biology">Commons</a></li> <li><span class="noviewer" typeof="mw:File"><span title="WikiProject"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/37/People_icon.svg/16px-People_icon.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/37/People_icon.svg/24px-People_icon.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/37/People_icon.svg/32px-People_icon.svg.png 2x" data-file-width="100" data-file-height="100" /></span></span> <a href="/wiki/Wikipedia:WikiProject_Biology" title="Wikipedia:WikiProject Biology">WikiProject</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"></div><div role="navigation" class="navbox" aria-labelledby="Artificial_induction_of_immunity_/_Immunization:_Vaccines,_Vaccination,_Infection,_Inoculation_(J07)548" style="padding:3px"><table class="nowraplinks hlist mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Vaccines" title="Template:Vaccines"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Vaccines" title="Template talk:Vaccines"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Vaccines" title="Special:EditPage/Template:Vaccines"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Artificial_induction_of_immunity_/_Immunization:_Vaccines,_Vaccination,_Infection,_Inoculation_(J07)548" style="font-size:114%;margin:0 4em"><a href="/wiki/Artificial_induction_of_immunity" title="Artificial induction of immunity">Artificial induction of immunity</a> / <a href="/wiki/Immunization" title="Immunization">Immunization</a>: <a href="/wiki/Vaccine" title="Vaccine">Vaccines</a>, <a href="/wiki/Vaccination" title="Vaccination">Vaccination</a>, <a href="/wiki/Infection" title="Infection">Infection</a>, <a href="/wiki/Inoculation" title="Inoculation">Inoculation</a> (<a href="/wiki/ATC_code_J07" title="ATC code J07">J07</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Development</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Immunologic_adjuvant" title="Immunologic adjuvant">Adjuvants</a></li> <li><a href="/wiki/Vaccine_ingredients" title="Vaccine ingredients">Vaccine ingredients</a> <ul><li><a href="/wiki/List_of_vaccine_excipients" title="List of vaccine excipients">list</a></li></ul></li> <li><a href="/wiki/Mathematical_modelling_of_infectious_diseases" title="Mathematical modelling of infectious diseases">Mathematical modelling</a></li> <li><a href="/wiki/Vaccine_storage" title="Vaccine storage">Storage</a></li> <li><a href="/wiki/Timeline_of_human_vaccines" title="Timeline of human vaccines">Timeline</a></li> <li><a href="/wiki/Vaccine_trial" title="Vaccine trial">Trials</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Classes</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Conjugate_vaccine" title="Conjugate vaccine">Conjugate</a></li> <li><a href="/wiki/Inactivated_vaccine" title="Inactivated vaccine">Inactivated</a></li> <li>Live <ul><li><a href="/wiki/Attenuated_vaccine" title="Attenuated vaccine">Attenuated</a></li> <li><a href="/wiki/Heterologous_vaccine" title="Heterologous vaccine">Heterologous</a></li></ul></li> <li><a href="/wiki/Subunit_vaccine" title="Subunit vaccine">Subunit/component</a> / <a href="/wiki/Peptide_vaccine" title="Peptide vaccine">Peptide</a> / <a href="/wiki/Virus-like_particle" title="Virus-like particle">Virus-like particle</a> / <a href="/wiki/Synthetic_vaccine" title="Synthetic vaccine">Synthetic</a></li> <li><a href="/wiki/DNA_vaccine" title="DNA vaccine">DNA</a> / <a href="/wiki/MRNA_vaccine" title="MRNA vaccine">mRNA</a></li> <li><a href="/wiki/Therapeutic_vaccines" title="Therapeutic vaccines">Therapeutic</a></li> <li><a href="/wiki/Toxoid" title="Toxoid">Toxoid</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Administration</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>Global: <ul><li><a href="/wiki/GAVI" title="GAVI">GAVI Alliance</a></li> <li><a href="/wiki/National_Immunization_Technical_Advisory_Group" title="National Immunization Technical Advisory Group">NITAG</a></li> <li><a href="/wiki/Strategic_Advisory_Group_of_Experts" title="Strategic Advisory Group of Experts">SAGE</a></li> <li><a href="/wiki/Vaccine_wastage" title="Vaccine wastage">Vaccine wastage</a></li> <li><a href="/wiki/Vaccination_policy" title="Vaccination policy">Policy</a></li> <li><a href="/wiki/Vaccination_schedule" title="Vaccination schedule">Schedule</a></li> <li><a href="/wiki/Vaccine_adverse_event" title="Vaccine adverse event">Vaccine injury</a></li></ul></li> <li>US: <ul><li><a href="/wiki/Advisory_Committee_on_Immunization_Practices" title="Advisory Committee on Immunization Practices">ACIP</a></li> <li><a href="/wiki/National_Vaccine_Injury_Compensation_Program" title="National Vaccine Injury Compensation Program">Vaccine court</a></li> <li><a href="/wiki/Vaccines_for_Children_Program" title="Vaccines for Children Program">Vaccines for Children Program</a></li> <li><a href="/wiki/Vaccine_Adverse_Event_Reporting_System" title="Vaccine Adverse Event Reporting System">VAERS</a></li> <li><a href="/wiki/Vaccine_Safety_Datalink" title="Vaccine Safety Datalink">VSD</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Vaccines</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Bacterial</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Anthrax_vaccine" title="Anthrax vaccine">Anthrax</a></li> <li><a href="/wiki/Brucellosis_vaccine" title="Brucellosis vaccine">Brucellosis</a></li> <li><a href="/wiki/Cholera_vaccine" title="Cholera vaccine">Cholera</a><sup>#</sup></li> <li><a href="/wiki/Diphtheria_vaccine" title="Diphtheria vaccine">Diphtheria</a><sup>#</sup></li> <li><a href="/wiki/Hib_vaccine" title="Hib vaccine">Hib</a><sup>#</sup></li> <li><a href="/wiki/Leptospirosis#Prevention" title="Leptospirosis">Leptospirosis</a></li> <li><a href="/wiki/Lyme_disease#Vaccination" title="Lyme disease">Lyme disease</a><sup>‡</sup></li> <li><a href="/wiki/Meningococcal_vaccine" title="Meningococcal vaccine">Meningococcus</a><sup>#</sup> <ul><li><a href="/wiki/MeNZB" title="MeNZB">MeNZB</a></li> <li><a href="/wiki/NmVac4-A/C/Y/W-135" title="NmVac4-A/C/Y/W-135">NmVac4-A/C/Y/W-135</a></li></ul></li> <li><a href="/wiki/Pertussis_vaccine" title="Pertussis vaccine">Pertussis</a><sup>#</sup></li> <li><a href="/wiki/Plague_vaccine" title="Plague vaccine">Plague</a></li> <li><a href="/wiki/Pneumococcal_vaccine" title="Pneumococcal vaccine">Pneumococcal</a><sup>#</sup> <ul><li><a href="/wiki/Pneumococcal_conjugate_vaccine" title="Pneumococcal conjugate vaccine">PCV</a></li> <li><a href="/wiki/Pneumococcal_polysaccharide_vaccine" title="Pneumococcal polysaccharide vaccine">PPSV</a></li></ul></li> <li><a href="/wiki/Q_fever#Prevention" title="Q fever">Q fever</a></li> <li><a href="/wiki/Tetanus_vaccine" title="Tetanus vaccine">Tetanus</a><sup>#</sup></li> <li><a href="/wiki/Tuberculosis_vaccines" title="Tuberculosis vaccines">Tuberculosis</a> <ul><li><a href="/wiki/BCG_vaccine" title="BCG vaccine">BCG</a><sup>#</sup></li></ul></li> <li><a href="/wiki/Typhoid_vaccine" title="Typhoid vaccine">Typhoid</a><sup>#</sup> <ul><li><a href="/wiki/Ty21a" title="Ty21a">Ty21a</a></li> <li><a href="/wiki/Vi_capsular_polysaccharide_vaccine" title="Vi capsular polysaccharide vaccine">ViCPS</a></li></ul></li> <li><a href="/wiki/Typhus_vaccine" title="Typhus vaccine">Typhus</a></li> <li>combination: <ul><li><a href="/wiki/DPT_vaccine" title="DPT vaccine">DPT/DTwP/DTaP</a></li> <li><a href="/wiki/Tetanus_vaccine" title="Tetanus vaccine">Td/Tdap</a></li></ul></li> <li>research: <ul><li><a href="/wiki/Clostridioides_difficile_infection#Research" title="Clostridioides difficile infection">Clostridioides difficile</a></li> <li><a href="/wiki/Group_B_streptococcal_infection#Vaccine" title="Group B streptococcal infection">Group B streptococcal disease</a></li> <li><a href="/wiki/Shigellosis#Vaccine" title="Shigellosis">Shigellosis</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Viral</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Adenovirus_vaccine" title="Adenovirus vaccine">Adenovirus</a></li> <li><a href="/wiki/Chikungunya_vaccine" title="Chikungunya vaccine">Chikungunya</a></li> <li><a href="/wiki/Ebola_vaccine" title="Ebola vaccine">Ebola</a> <ul><li><a href="/wiki/RVSV-ZEBOV_vaccine" title="RVSV-ZEBOV vaccine">rVSV-ZEBOV</a></li></ul></li> <li><a href="/wiki/Influenza_vaccine" title="Influenza vaccine">Flu</a><sup>#</sup> <ul><li><a href="/wiki/2009_swine_flu_pandemic_vaccine" title="2009 swine flu pandemic vaccine">H1N1</a> (<a href="/wiki/Pandemrix" title="Pandemrix">Pandemrix</a>)</li> <li><a href="/wiki/H5N1_vaccine" title="H5N1 vaccine">H5N1</a></li> <li><a href="/wiki/H5N8_vaccine" title="H5N8 vaccine">H5N8</a></li> <li><a href="/wiki/Live_attenuated_influenza_vaccine" title="Live attenuated influenza vaccine">LAIV</a></li></ul></li> <li><a href="/wiki/Hantavirus_vaccine" title="Hantavirus vaccine">Hantavirus</a></li> <li><a href="/wiki/Hepatitis_A_vaccine" title="Hepatitis A vaccine">Hepatitis A</a><sup>#</sup></li> <li><a href="/wiki/Hepatitis_B_vaccine" title="Hepatitis B vaccine">Hepatitis B</a><sup>#</sup></li> <li><a href="/wiki/Hepatitis_E#Vaccines" title="Hepatitis E">Hepatitis E</a></li> <li><a href="/wiki/HPV_vaccine" title="HPV vaccine">HPV</a><sup>#</sup> <ul><li><a href="/wiki/Cervarix" title="Cervarix">Cervarix</a></li> <li><a href="/wiki/Gardasil" title="Gardasil">Gardasil</a></li></ul></li> <li><a href="/wiki/Japanese_encephalitis_vaccine" title="Japanese encephalitis vaccine">Japanese encephalitis</a><sup>#</sup></li> <li><a href="/wiki/Measles_vaccine" title="Measles vaccine">Measles</a><sup>#</sup></li> <li><a href="/wiki/Mpox_vaccine" class="mw-redirect" title="Mpox vaccine">Mpox</a></li> <li><a href="/wiki/Mumps_vaccine" title="Mumps vaccine">Mumps</a><sup>#</sup></li> <li><a href="/wiki/Polio_vaccine" title="Polio vaccine">Polio</a><sup>#</sup> <ul><li><a href="/wiki/Polio_vaccine#Attenuated" title="Polio vaccine">Sabin</a></li> <li><a href="/wiki/Polio_vaccine#Inactivated" title="Polio vaccine">Salk</a></li></ul></li> <li><a href="/wiki/Rabies_vaccine" title="Rabies vaccine">Rabies</a><sup>#</sup></li> <li><a href="/wiki/Rotavirus_vaccine" title="Rotavirus vaccine">Rotavirus</a><sup>#</sup></li> <li><a href="/wiki/Rubella_vaccine" title="Rubella vaccine">Rubella</a><sup>#</sup></li> <li><a href="/wiki/COVID-19_vaccine" title="COVID-19 vaccine">SARS-CoV-2</a> <ul><li><a href="/wiki/Corbevax" title="Corbevax">Corbevax</a><sup>†</sup></li> <li><a href="/wiki/Covaxin" title="Covaxin">Bharat Biotech</a><sup>†</sup></li> <li><a href="/wiki/Convidecia" title="Convidecia">CanSino</a><sup>†</sup></li> <li><a href="/wiki/CoronaVac" title="CoronaVac">CoronaVac</a><sup>†</sup></li> <li><a href="/wiki/EpiVacCorona" title="EpiVacCorona">EpiVacCorona</a><sup>†</sup></li> <li><a href="/wiki/Janssen_COVID-19_vaccine" title="Janssen COVID-19 vaccine">Janssen</a></li> <li><a href="/wiki/Zapomeran" title="Zapomeran">Kostaive</a></li> <li><a href="/wiki/Moderna_COVID-19_vaccine" title="Moderna COVID-19 vaccine">Moderna</a></li> <li><a href="/wiki/Novavax_COVID-19_vaccine" title="Novavax COVID-19 vaccine">Novavax</a></li> <li><a href="/wiki/Oxford%E2%80%93AstraZeneca_COVID-19_vaccine" title="Oxford–AstraZeneca COVID-19 vaccine">Oxford–AstraZeneca</a></li> <li><a href="/wiki/Pfizer%E2%80%93BioNTech_COVID-19_vaccine" title="Pfizer–BioNTech COVID-19 vaccine">Pfizer–BioNTech</a></li> <li><a href="/wiki/Sanofi%E2%80%93GSK_COVID-19_vaccine" title="Sanofi–GSK COVID-19 vaccine">Sanofi–GSK</a><sup>†</sup></li> <li><a href="/wiki/Sinopharm_BIBP_COVID-19_vaccine" title="Sinopharm BIBP COVID-19 vaccine">Sinopharm BIBP</a><sup>†</sup></li> <li><a href="/wiki/Skycovione" title="Skycovione">Skycovione</a><sup>†</sup></li> <li><a href="/wiki/Sputnik_V_COVID-19_vaccine" title="Sputnik V COVID-19 vaccine">Sputnik V</a><sup>†</sup></li> <li><a href="/wiki/Valneva_COVID-19_vaccine" title="Valneva COVID-19 vaccine">Valneva</a><sup>†</sup></li></ul></li> <li><a href="/wiki/Respiratory_syncytial_virus_vaccine" title="Respiratory syncytial virus vaccine">Respiratory syncytial virus (RSV)</a></li> <li><a href="/wiki/Smallpox_vaccine" title="Smallpox vaccine">Smallpox</a></li> <li><a href="/wiki/Tick-borne_encephalitis_vaccine" title="Tick-borne encephalitis vaccine">Tick-borne encephalitis</a><sup>#</sup></li> <li>Varicella zoster <ul><li><a href="/wiki/Varicella_vaccine" title="Varicella vaccine">Chicken pox</a><sup>#</sup></li> <li><a href="/wiki/Zoster_vaccine" title="Zoster vaccine">Shingles</a></li></ul></li> <li><a href="/wiki/Yellow_fever_vaccine" title="Yellow fever vaccine">Yellow fever</a><sup>#</sup></li> <li>combination: <ul><li><a href="/wiki/Hepatitis_A_and_B_vaccine" title="Hepatitis A and B vaccine">Hepatitis A and B</a></li> <li><a href="/wiki/MMR_vaccine" title="MMR vaccine">MMR</a></li> <li><a href="/wiki/MMRV_vaccine" title="MMRV vaccine">MMRV</a></li></ul></li> <li>research: <ul><li><a href="/wiki/Cytomegalovirus_vaccine" title="Cytomegalovirus vaccine">Cytomegalovirus</a></li> <li><a href="/wiki/Dengue_vaccine" title="Dengue vaccine">Dengue</a><sup>#</sup></li> <li><a href="/wiki/Epstein%E2%80%93Barr_virus_vaccine" title="Epstein–Barr virus vaccine">Epstein–Barr virus</a></li> <li><a href="/wiki/Hepatitis_C_vaccine" title="Hepatitis C vaccine">Hepatitis C</a></li> <li><a href="/wiki/Herpes_simplex_research" title="Herpes simplex research">Herpes simplex</a></li> <li><a href="/wiki/HIV_vaccine_development" title="HIV vaccine development">HIV</a></li> <li><a href="/wiki/Zika_virus_vaccine" title="Zika virus vaccine">Zika</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Protozoan</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Malaria_vaccine" title="Malaria vaccine">Malaria</a> <ul><li><a href="/wiki/RTS,S" title="RTS,S">RTS,S</a></li></ul></li> <li>research: <ul><li><a href="/wiki/Trypanosomiasis_vaccine" title="Trypanosomiasis vaccine">Trypanosomiasis</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Helminthiasis" title="Helminthiasis">Helminthiasis</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>research: <ul><li><a href="/wiki/Hookworm_vaccine" title="Hookworm vaccine">Hookworm</a></li> <li><a href="/wiki/Schistosomiasis_vaccine" title="Schistosomiasis vaccine">Schistosomiasis</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Androvax" title="Androvax">Androvax (androstenedione albumin)</a></li> <li><a href="/wiki/Cancer_vaccine" title="Cancer vaccine">Cancer vaccines</a> <ul><li><a href="/wiki/ALVAC-CEA_vaccine" title="ALVAC-CEA vaccine">ALVAC-CEA</a></li> <li><a href="/wiki/BCG_vaccine" title="BCG vaccine">BCG</a><sup>#</sup></li> <li><a href="/wiki/Hepatitis_B_vaccine" title="Hepatitis B vaccine">Hepatitis B</a><sup>#</sup></li> <li><a href="/wiki/HPV_vaccine" title="HPV vaccine">HPV</a><sup>#</sup> <ul><li><a href="/wiki/Cervarix" title="Cervarix">Cervarix</a></li> <li><a href="/wiki/Gardasil" title="Gardasil">Gardasil</a></li></ul></li> <li><a href="/wiki/Prostvac" title="Prostvac">Prostvac</a></li></ul></li> <li><a href="/wiki/NicVAX" title="NicVAX">NicVAX</a></li> <li><a href="/wiki/Ovandrotone_albumin" title="Ovandrotone albumin">Ovandrotone albumin (Fecundin)</a></li> <li><a href="/wiki/TA-CD" title="TA-CD">TA-CD</a></li> <li><a href="/wiki/TA-NIC" title="TA-NIC">TA-NIC</a></li> <li>combination: <ul><li><a href="/wiki/DTaP-IPV/Hib_vaccine" title="DTaP-IPV/Hib vaccine">DTaP-IPV/Hib</a></li> <li><a href="/wiki/DTaP-IPV-HepB_vaccine" title="DTaP-IPV-HepB vaccine">DTaP-IPV-HepB</a></li> <li><a href="/wiki/DTwP-HepB-Hib_vaccine" title="DTwP-HepB-Hib vaccine">DTwP-HepB-Hib</a></li> <li><a href="/wiki/Hexavalent_vaccine" title="Hexavalent vaccine">Hexavalent vaccine</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Inventors/<br />researchers</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Edward_Jenner" title="Edward Jenner">Edward Jenner</a></li> <li><a href="/wiki/Louis_Pasteur" title="Louis Pasteur">Louis Pasteur</a></li> <li><a href="/wiki/Hilary_Koprowski" title="Hilary Koprowski">Hilary Koprowski</a></li> <li><a href="/wiki/Jonas_Salk" title="Jonas Salk">Jonas Salk</a></li> <li><a href="/wiki/John_Franklin_Enders" title="John Franklin Enders">John Franklin Enders</a></li> <li><a href="/wiki/Maurice_Hilleman" title="Maurice Hilleman">Maurice Hilleman</a></li> <li><a href="/wiki/Stanley_Plotkin" title="Stanley Plotkin">Stanley Plotkin</a></li> <li><a href="/wiki/H._Fred_Clark" title="H. Fred Clark">H. Fred Clark</a></li> <li><a href="/wiki/Paul_Offit" title="Paul Offit">Paul Offit</a></li> <li><a href="/wiki/Katalin_Karik%C3%B3" title="Katalin Karikó">Katalin Karikó</a></li> <li><a href="/wiki/Drew_Weissman" title="Drew Weissman">Drew Weissman</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Controversy</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Vaccine_hesitancy" title="Vaccine hesitancy">General</a></li> <li><a href="/wiki/MMR_vaccine_and_autism" title="MMR vaccine and autism">MMR</a> (<a href="/wiki/Lancet_MMR_autism_fraud" title="Lancet MMR autism fraud"><i>Lancet</i> MMR autism fraud</a>)</li> <li><a href="/wiki/National_Childhood_Vaccine_Injury_Act" title="National Childhood Vaccine Injury Act">NCVIA</a></li> <li><a href="/wiki/Pox_party" title="Pox party">Pox party</a></li> <li><a href="/wiki/Thiomersal_and_vaccines" title="Thiomersal and vaccines">Thiomersal</a></li> <li><a href="/wiki/Vaccines_and_SIDS" title="Vaccines and SIDS">Vaccines and SIDS</a></li> <li><i><a href="/wiki/Cedillo_v._Secretary_of_Health_and_Human_Services" title="Cedillo v. Secretary of Health and Human Services">Cedillo v. Secretary of Health and Human Services</a></i></li> <li><a href="/wiki/Alternative_vaccination_schedule" title="Alternative vaccination schedule">Alternative vaccination schedule</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Related</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a class="mw-selflink selflink">Epidemiology</a></li> <li><a href="/wiki/Eradication_of_infectious_diseases" title="Eradication of infectious diseases">Eradication of infectious diseases</a></li> <li><a href="/wiki/Vaccinate_Your_Family" title="Vaccinate Your Family">Vaccinate Your Family</a></li> <li><a href="/wiki/List_of_vaccine_topics" title="List of vaccine topics">List of vaccine topics</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background: transparent; padding: 0px;"><div><div class="hlist"> <ul><li><sup>#</sup><a href="/wiki/WHO_Model_List_of_Essential_Medicines" title="WHO Model List of Essential Medicines">WHO-EM</a></li> <li><sup>‡</sup><a href="/wiki/List_of_withdrawn_drugs" title="List of withdrawn drugs">Withdrawn</a> from market</li> <li><a href="/wiki/Clinical_trial" title="Clinical trial">Clinical trials</a>: <ul><li><sup>†</sup><a href="/wiki/Phases_of_clinical_research#Phase_III" title="Phases of clinical research">Phase III</a></li> <li><sup>§</sup>Never to phase III</li></ul></li></ul> </div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"></div><div role="navigation" class="navbox" aria-labelledby="Statistics636" style="padding:3px"><table class="nowraplinks hlist mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Statistics" title="Template:Statistics"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Statistics" title="Template talk:Statistics"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Statistics" title="Special:EditPage/Template:Statistics"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Statistics636" style="font-size:114%;margin:0 4em"><a href="/wiki/Statistics" title="Statistics">Statistics</a></div></th></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <ul><li><a href="/wiki/Outline_of_statistics" title="Outline of statistics">Outline</a></li> <li><a href="/wiki/List_of_statistics_articles" title="List of statistics articles">Index</a></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div id="Descriptive_statistics636" style="font-size:114%;margin:0 4em"><a href="/wiki/Descriptive_statistics" title="Descriptive statistics">Descriptive statistics</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Continuous_probability_distribution" class="mw-redirect" title="Continuous probability distribution">Continuous data</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;"><a href="/wiki/Central_tendency" title="Central tendency">Center</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Mean" title="Mean">Mean</a> <ul><li><a href="/wiki/Arithmetic_mean" title="Arithmetic mean">Arithmetic</a></li> <li><a href="/wiki/Arithmetic%E2%80%93geometric_mean" title="Arithmetic–geometric mean">Arithmetic-Geometric</a></li> <li><a href="/wiki/Contraharmonic_mean" title="Contraharmonic mean">Contraharmonic</a></li> <li><a href="/wiki/Cubic_mean" title="Cubic mean">Cubic</a></li> <li><a href="/wiki/Generalized_mean" title="Generalized mean">Generalized/power</a></li> <li><a href="/wiki/Geometric_mean" title="Geometric mean">Geometric</a></li> <li><a href="/wiki/Harmonic_mean" title="Harmonic mean">Harmonic</a></li> <li><a href="/wiki/Heronian_mean" title="Heronian mean">Heronian</a></li> <li><a href="/wiki/Heinz_mean" title="Heinz mean">Heinz</a></li> <li><a href="/wiki/Lehmer_mean" title="Lehmer mean">Lehmer</a></li></ul></li> <li><a href="/wiki/Median" title="Median">Median</a></li> <li><a href="/wiki/Mode_(statistics)" title="Mode (statistics)">Mode</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;"><a href="/wiki/Statistical_dispersion" title="Statistical dispersion">Dispersion</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Average_absolute_deviation" title="Average absolute deviation">Average absolute deviation</a></li> <li><a href="/wiki/Coefficient_of_variation" title="Coefficient of variation">Coefficient of variation</a></li> <li><a href="/wiki/Interquartile_range" title="Interquartile range">Interquartile range</a></li> <li><a href="/wiki/Percentile" title="Percentile">Percentile</a></li> <li><a href="/wiki/Range_(statistics)" title="Range (statistics)">Range</a></li> <li><a href="/wiki/Standard_deviation" title="Standard deviation">Standard deviation</a></li> <li><a href="/wiki/Variance#Sample_variance" title="Variance">Variance</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;"><a href="/wiki/Shape_of_the_distribution" class="mw-redirect" title="Shape of the distribution">Shape</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Central_limit_theorem" title="Central limit theorem">Central limit theorem</a></li> <li><a href="/wiki/Moment_(mathematics)" title="Moment (mathematics)">Moments</a> <ul><li><a href="/wiki/Kurtosis" title="Kurtosis">Kurtosis</a></li> <li><a href="/wiki/L-moment" title="L-moment">L-moments</a></li> <li><a href="/wiki/Skewness" title="Skewness">Skewness</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Count_data" title="Count data">Count data</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Index_of_dispersion" title="Index of dispersion">Index of dispersion</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em">Summary tables</th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Contingency_table" title="Contingency table">Contingency table</a></li> <li><a href="/wiki/Frequency_distribution" class="mw-redirect" title="Frequency distribution">Frequency distribution</a></li> <li><a href="/wiki/Grouped_data" title="Grouped data">Grouped data</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Correlation_and_dependence" class="mw-redirect" title="Correlation and dependence">Dependence</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Partial_correlation" title="Partial correlation">Partial correlation</a></li> <li><a href="/wiki/Pearson_correlation_coefficient" title="Pearson correlation coefficient">Pearson product-moment correlation</a></li> <li><a href="/wiki/Rank_correlation" title="Rank correlation">Rank correlation</a> <ul><li><a href="/wiki/Kendall_rank_correlation_coefficient" title="Kendall rank correlation coefficient">Kendall's τ</a></li> <li><a href="/wiki/Spearman%27s_rank_correlation_coefficient" title="Spearman's rank correlation coefficient">Spearman's ρ</a></li></ul></li> <li><a href="/wiki/Scatter_plot" title="Scatter plot">Scatter plot</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Statistical_graphics" title="Statistical graphics">Graphics</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Bar_chart" title="Bar chart">Bar chart</a></li> <li><a href="/wiki/Biplot" title="Biplot">Biplot</a></li> <li><a href="/wiki/Box_plot" title="Box plot">Box plot</a></li> <li><a href="/wiki/Control_chart" title="Control chart">Control chart</a></li> <li><a href="/wiki/Correlogram" title="Correlogram">Correlogram</a></li> <li><a href="/wiki/Fan_chart_(statistics)" title="Fan chart (statistics)">Fan chart</a></li> <li><a href="/wiki/Forest_plot" title="Forest plot">Forest plot</a></li> <li><a href="/wiki/Histogram" title="Histogram">Histogram</a></li> <li><a href="/wiki/Pie_chart" title="Pie chart">Pie chart</a></li> <li><a href="/wiki/Q%E2%80%93Q_plot" title="Q–Q plot">Q–Q plot</a></li> <li><a href="/wiki/Radar_chart" title="Radar chart">Radar chart</a></li> <li><a href="/wiki/Run_chart" title="Run chart">Run chart</a></li> <li><a href="/wiki/Scatter_plot" title="Scatter plot">Scatter plot</a></li> <li><a href="/wiki/Stem-and-leaf_display" title="Stem-and-leaf display">Stem-and-leaf display</a></li> <li><a href="/wiki/Violin_plot" title="Violin plot">Violin plot</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div id="Data_collection636" style="font-size:114%;margin:0 4em"><a href="/wiki/Data_collection" title="Data collection">Data collection</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Design_of_experiments" title="Design of experiments">Study design</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Effect_size" title="Effect size">Effect size</a></li> <li><a href="/wiki/Missing_data" title="Missing data">Missing data</a></li> <li><a href="/wiki/Optimal_design" class="mw-redirect" title="Optimal design">Optimal design</a></li> <li><a href="/wiki/Statistical_population" title="Statistical population">Population</a></li> <li><a href="/wiki/Replication_(statistics)" title="Replication (statistics)">Replication</a></li> <li><a href="/wiki/Sample_size_determination" title="Sample size determination">Sample size determination</a></li> <li><a href="/wiki/Statistic" title="Statistic">Statistic</a></li> <li><a href="/wiki/Statistical_power" class="mw-redirect" title="Statistical power">Statistical power</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Survey_methodology" title="Survey methodology">Survey methodology</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Sampling_(statistics)" title="Sampling (statistics)">Sampling</a> <ul><li><a href="/wiki/Cluster_sampling" title="Cluster sampling">Cluster</a></li> <li><a href="/wiki/Stratified_sampling" title="Stratified sampling">Stratified</a></li></ul></li> <li><a href="/wiki/Opinion_poll" title="Opinion poll">Opinion poll</a></li> <li><a href="/wiki/Questionnaire" title="Questionnaire">Questionnaire</a></li> <li><a href="/wiki/Standard_error" title="Standard error">Standard error</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Experiment" title="Experiment">Controlled experiments</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Blocking_(statistics)" title="Blocking (statistics)">Blocking</a></li> <li><a href="/wiki/Factorial_experiment" title="Factorial experiment">Factorial experiment</a></li> <li><a href="/wiki/Interaction_(statistics)" title="Interaction (statistics)">Interaction</a></li> <li><a href="/wiki/Random_assignment" title="Random assignment">Random assignment</a></li> <li><a href="/wiki/Randomized_controlled_trial" title="Randomized controlled trial">Randomized controlled trial</a></li> <li><a href="/wiki/Randomized_experiment" title="Randomized experiment">Randomized experiment</a></li> <li><a href="/wiki/Scientific_control" title="Scientific control">Scientific control</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em">Adaptive designs</th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Adaptive_clinical_trial" class="mw-redirect" title="Adaptive clinical trial">Adaptive clinical trial</a></li> <li><a href="/wiki/Stochastic_approximation" title="Stochastic approximation">Stochastic approximation</a></li> <li><a href="/wiki/Up-and-Down_Designs" class="mw-redirect" title="Up-and-Down Designs">Up-and-down designs</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Observational_study" title="Observational study">Observational studies</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cohort_study" title="Cohort study">Cohort study</a></li> <li><a href="/wiki/Cross-sectional_study" title="Cross-sectional study">Cross-sectional study</a></li> <li><a href="/wiki/Natural_experiment" title="Natural experiment">Natural experiment</a></li> <li><a href="/wiki/Quasi-experiment" title="Quasi-experiment">Quasi-experiment</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div id="Statistical_inference636" style="font-size:114%;margin:0 4em"><a href="/wiki/Statistical_inference" title="Statistical inference">Statistical inference</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Statistical_theory" title="Statistical theory">Statistical theory</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Population_(statistics)" class="mw-redirect" title="Population (statistics)">Population</a></li> <li><a href="/wiki/Statistic" title="Statistic">Statistic</a></li> <li><a href="/wiki/Probability_distribution" title="Probability distribution">Probability distribution</a></li> <li><a href="/wiki/Sampling_distribution" title="Sampling distribution">Sampling distribution</a> <ul><li><a href="/wiki/Order_statistic" title="Order statistic">Order statistic</a></li></ul></li> <li><a href="/wiki/Empirical_distribution_function" title="Empirical distribution function">Empirical distribution</a> <ul><li><a href="/wiki/Density_estimation" title="Density estimation">Density estimation</a></li></ul></li> <li><a href="/wiki/Statistical_model" title="Statistical model">Statistical model</a> <ul><li><a href="/wiki/Model_specification" class="mw-redirect" title="Model specification">Model specification</a></li> <li><a href="/wiki/Lp_space" title="Lp space">L<sup><i>p</i></sup> space</a></li></ul></li> <li><a href="/wiki/Statistical_parameter" title="Statistical parameter">Parameter</a> <ul><li><a href="/wiki/Location_parameter" title="Location parameter">location</a></li> <li><a href="/wiki/Scale_parameter" title="Scale parameter">scale</a></li> <li><a href="/wiki/Shape_parameter" title="Shape parameter">shape</a></li></ul></li> <li><a href="/wiki/Parametric_statistics" title="Parametric statistics">Parametric family</a> <ul><li><a href="/wiki/Likelihood_function" title="Likelihood function">Likelihood</a> <a href="/wiki/Monotone_likelihood_ratio" title="Monotone likelihood ratio"><span style="font-size:85%;">(monotone)</span></a></li> <li><a href="/wiki/Location%E2%80%93scale_family" title="Location–scale family">Location–scale family</a></li> <li><a href="/wiki/Exponential_family" title="Exponential family">Exponential family</a></li></ul></li> <li><a href="/wiki/Completeness_(statistics)" title="Completeness (statistics)">Completeness</a></li> <li><a href="/wiki/Sufficient_statistic" title="Sufficient statistic">Sufficiency</a></li> <li><a href="/wiki/Plug-in_principle" class="mw-redirect" title="Plug-in principle">Statistical functional</a> <ul><li><a href="/wiki/Bootstrapping_(statistics)" title="Bootstrapping (statistics)">Bootstrap</a></li> <li><a href="/wiki/U-statistic" title="U-statistic">U</a></li> <li><a href="/wiki/V-statistic" title="V-statistic">V</a></li></ul></li> <li><a href="/wiki/Optimal_decision" title="Optimal decision">Optimal decision</a> <ul><li><a href="/wiki/Loss_function" title="Loss function">loss function</a></li></ul></li> <li><a href="/wiki/Efficiency_(statistics)" title="Efficiency (statistics)">Efficiency</a></li> <li><a href="/wiki/Statistical_distance" title="Statistical distance">Statistical distance</a> <ul><li><a href="/wiki/Divergence_(statistics)" title="Divergence (statistics)">divergence</a></li></ul></li> <li><a href="/wiki/Asymptotic_theory_(statistics)" title="Asymptotic theory (statistics)">Asymptotics</a></li> <li><a href="/wiki/Robust_statistics" title="Robust statistics">Robustness</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Frequentist_inference" title="Frequentist inference">Frequentist inference</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;"><a href="/wiki/Point_estimation" title="Point estimation">Point estimation</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Estimating_equations" title="Estimating equations">Estimating equations</a> <ul><li><a href="/wiki/Maximum_likelihood" class="mw-redirect" title="Maximum likelihood">Maximum likelihood</a></li> <li><a href="/wiki/Method_of_moments_(statistics)" title="Method of moments (statistics)">Method of moments</a></li> <li><a href="/wiki/M-estimator" title="M-estimator">M-estimator</a></li> <li><a href="/wiki/Minimum_distance_estimation" class="mw-redirect" title="Minimum distance estimation">Minimum distance</a></li></ul></li> <li><a href="/wiki/Bias_of_an_estimator" title="Bias of an estimator">Unbiased estimators</a> <ul><li><a href="/wiki/Minimum-variance_unbiased_estimator" title="Minimum-variance unbiased estimator">Mean-unbiased minimum-variance</a> <ul><li><a href="/wiki/Rao%E2%80%93Blackwell_theorem" title="Rao–Blackwell theorem">Rao–Blackwellization</a></li> <li><a href="/wiki/Lehmann%E2%80%93Scheff%C3%A9_theorem" title="Lehmann–Scheffé theorem">Lehmann–Scheffé theorem</a></li></ul></li> <li><a href="/wiki/Median-unbiased_estimator" class="mw-redirect" title="Median-unbiased estimator">Median unbiased</a></li></ul></li> <li><a href="/wiki/Plug-in_principle" class="mw-redirect" title="Plug-in principle">Plug-in</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;"><a href="/wiki/Interval_estimation" title="Interval estimation">Interval estimation</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Confidence_interval" title="Confidence interval">Confidence interval</a></li> <li><a href="/wiki/Pivotal_quantity" title="Pivotal quantity">Pivot</a></li> <li><a href="/wiki/Likelihood_interval" class="mw-redirect" title="Likelihood interval">Likelihood interval</a></li> <li><a href="/wiki/Prediction_interval" title="Prediction interval">Prediction interval</a></li> <li><a href="/wiki/Tolerance_interval" title="Tolerance interval">Tolerance interval</a></li> <li><a href="/wiki/Resampling_(statistics)" title="Resampling (statistics)">Resampling</a> <ul><li><a href="/wiki/Bootstrapping_(statistics)" title="Bootstrapping (statistics)">Bootstrap</a></li> <li><a href="/wiki/Jackknife_resampling" title="Jackknife resampling">Jackknife</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;"><a href="/wiki/Statistical_hypothesis_testing" class="mw-redirect" title="Statistical hypothesis testing">Testing hypotheses</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/One-_and_two-tailed_tests" title="One- and two-tailed tests">1- & 2-tails</a></li> <li><a href="/wiki/Power_(statistics)" title="Power (statistics)">Power</a> <ul><li><a href="/wiki/Uniformly_most_powerful_test" title="Uniformly most powerful test">Uniformly most powerful test</a></li></ul></li> <li><a href="/wiki/Permutation_test" title="Permutation test">Permutation test</a> <ul><li><a href="/wiki/Randomization_test" class="mw-redirect" title="Randomization test">Randomization test</a></li></ul></li> <li><a href="/wiki/Multiple_comparisons" class="mw-redirect" title="Multiple comparisons">Multiple comparisons</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;"><a href="/wiki/Parametric_statistics" title="Parametric statistics">Parametric tests</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Likelihood-ratio_test" title="Likelihood-ratio test">Likelihood-ratio</a></li> <li><a href="/wiki/Score_test" title="Score test">Score/Lagrange multiplier</a></li> <li><a href="/wiki/Wald_test" title="Wald test">Wald</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/List_of_statistical_tests" title="List of statistical tests">Specific tests</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><td colspan="2" class="navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Z-test" title="Z-test"><i>Z</i>-test <span style="font-size:85%;">(normal)</span></a></li> <li><a href="/wiki/Student%27s_t-test" title="Student's t-test">Student's <i>t</i>-test</a></li> <li><a href="/wiki/F-test" title="F-test"><i>F</i>-test</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;"><a href="/wiki/Goodness_of_fit" title="Goodness of fit">Goodness of fit</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Chi-squared_test" title="Chi-squared test">Chi-squared</a></li> <li><a href="/wiki/G-test" title="G-test"><i>G</i>-test</a></li> <li><a href="/wiki/Kolmogorov%E2%80%93Smirnov_test" title="Kolmogorov–Smirnov test">Kolmogorov–Smirnov</a></li> <li><a href="/wiki/Anderson%E2%80%93Darling_test" title="Anderson–Darling test">Anderson–Darling</a></li> <li><a href="/wiki/Lilliefors_test" title="Lilliefors test">Lilliefors</a></li> <li><a href="/wiki/Jarque%E2%80%93Bera_test" title="Jarque–Bera test">Jarque–Bera</a></li> <li><a href="/wiki/Shapiro%E2%80%93Wilk_test" title="Shapiro–Wilk test">Normality <span style="font-size:85%;">(Shapiro–Wilk)</span></a></li> <li><a href="/wiki/Likelihood-ratio_test" title="Likelihood-ratio test">Likelihood-ratio test</a></li> <li><a href="/wiki/Model_selection" title="Model selection">Model selection</a> <ul><li><a href="/wiki/Cross-validation_(statistics)" title="Cross-validation (statistics)">Cross validation</a></li> <li><a href="/wiki/Akaike_information_criterion" title="Akaike information criterion">AIC</a></li> <li><a href="/wiki/Bayesian_information_criterion" title="Bayesian information criterion">BIC</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;"><a href="/wiki/Rank_statistics" class="mw-redirect" title="Rank statistics">Rank statistics</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Sign_test" title="Sign test">Sign</a> <ul><li><a href="/wiki/Sample_median" class="mw-redirect" title="Sample median">Sample median</a></li></ul></li> <li><a href="/wiki/Wilcoxon_signed-rank_test" title="Wilcoxon signed-rank test">Signed rank <span style="font-size:85%;">(Wilcoxon)</span></a> <ul><li><a href="/wiki/Hodges%E2%80%93Lehmann_estimator" title="Hodges–Lehmann estimator">Hodges–Lehmann estimator</a></li></ul></li> <li><a href="/wiki/Mann%E2%80%93Whitney_U_test" title="Mann–Whitney U test">Rank sum <span style="font-size:85%;">(Mann–Whitney)</span></a></li> <li><a href="/wiki/Nonparametric_statistics" title="Nonparametric statistics">Nonparametric</a> <a href="/wiki/Analysis_of_variance" title="Analysis of variance">anova</a> <ul><li><a href="/wiki/Kruskal%E2%80%93Wallis_test" title="Kruskal–Wallis test">1-way <span style="font-size:85%;">(Kruskal–Wallis)</span></a></li> <li><a href="/wiki/Friedman_test" title="Friedman test">2-way <span style="font-size:85%;">(Friedman)</span></a></li> <li><a href="/wiki/Jonckheere%27s_trend_test" title="Jonckheere's trend test">Ordered alternative <span style="font-size:85%;">(Jonckheere–Terpstra)</span></a></li></ul></li> <li><a href="/wiki/Van_der_Waerden_test" title="Van der Waerden test">Van der Waerden test</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Bayesian_inference" title="Bayesian inference">Bayesian inference</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Bayesian_probability" title="Bayesian probability">Bayesian probability</a> <ul><li><a href="/wiki/Prior_probability" title="Prior probability">prior</a></li> <li><a href="/wiki/Posterior_probability" title="Posterior probability">posterior</a></li></ul></li> <li><a href="/wiki/Credible_interval" title="Credible interval">Credible interval</a></li> <li><a href="/wiki/Bayes_factor" title="Bayes factor">Bayes factor</a></li> <li><a href="/wiki/Bayes_estimator" title="Bayes estimator">Bayesian estimator</a> <ul><li><a href="/wiki/Maximum_a_posteriori_estimation" title="Maximum a posteriori estimation">Maximum posterior estimator</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div id="CorrelationRegression_analysis636" style="font-size:114%;margin:0 4em"><div class="hlist"><ul><li><a href="/wiki/Correlation_and_dependence" class="mw-redirect" title="Correlation and dependence">Correlation</a></li><li><a href="/wiki/Regression_analysis" title="Regression analysis">Regression analysis</a></li></ul></div></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Correlation_and_dependence" class="mw-redirect" title="Correlation and dependence">Correlation</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Pearson_product-moment_correlation_coefficient" class="mw-redirect" title="Pearson product-moment correlation coefficient">Pearson product-moment</a></li> <li><a href="/wiki/Partial_correlation" title="Partial correlation">Partial correlation</a></li> <li><a href="/wiki/Confounding" title="Confounding">Confounding variable</a></li> <li><a href="/wiki/Coefficient_of_determination" title="Coefficient of determination">Coefficient of determination</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Regression_analysis" title="Regression analysis">Regression analysis</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Errors_and_residuals" title="Errors and residuals">Errors and residuals</a></li> <li><a href="/wiki/Regression_validation" title="Regression validation">Regression validation</a></li> <li><a href="/wiki/Mixed_model" title="Mixed model">Mixed effects models</a></li> <li><a href="/wiki/Simultaneous_equations_model" title="Simultaneous equations model">Simultaneous equations models</a></li> <li><a href="/wiki/Multivariate_adaptive_regression_splines" class="mw-redirect" title="Multivariate adaptive regression splines">Multivariate adaptive regression splines (MARS)</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Linear_regression" title="Linear regression">Linear regression</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Simple_linear_regression" title="Simple linear regression">Simple linear regression</a></li> <li><a href="/wiki/Ordinary_least_squares" title="Ordinary least squares">Ordinary least squares</a></li> <li><a href="/wiki/General_linear_model" title="General linear model">General linear model</a></li> <li><a href="/wiki/Bayesian_linear_regression" title="Bayesian linear regression">Bayesian regression</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em">Non-standard predictors</th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Nonlinear_regression" title="Nonlinear regression">Nonlinear regression</a></li> <li><a href="/wiki/Nonparametric_regression" title="Nonparametric regression">Nonparametric</a></li> <li><a href="/wiki/Semiparametric_regression" title="Semiparametric regression">Semiparametric</a></li> <li><a href="/wiki/Isotonic_regression" title="Isotonic regression">Isotonic</a></li> <li><a href="/wiki/Robust_regression" title="Robust regression">Robust</a></li> <li><a href="/wiki/Homoscedasticity_and_heteroscedasticity" title="Homoscedasticity and heteroscedasticity">Homoscedasticity and Heteroscedasticity</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Generalized_linear_model" title="Generalized linear model">Generalized linear model</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Exponential_family" title="Exponential family">Exponential families</a></li> <li><a href="/wiki/Logistic_regression" title="Logistic regression">Logistic <span style="font-size:85%;">(Bernoulli)</span></a> / <a href="/wiki/Binomial_regression" title="Binomial regression">Binomial</a> / <a href="/wiki/Poisson_regression" title="Poisson regression">Poisson regressions</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Partition_of_sums_of_squares" title="Partition of sums of squares">Partition of variance</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Analysis_of_variance" title="Analysis of variance">Analysis of variance (ANOVA, anova)</a></li> <li><a href="/wiki/Analysis_of_covariance" title="Analysis of covariance">Analysis of covariance</a></li> <li><a href="/wiki/Multivariate_analysis_of_variance" title="Multivariate analysis of variance">Multivariate ANOVA</a></li> <li><a href="/wiki/Degrees_of_freedom_(statistics)" title="Degrees of freedom (statistics)">Degrees of freedom</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div id="Categorical_/_Multivariate_/_Time-series_/_Survival_analysis636" style="font-size:114%;margin:0 4em"><a href="/wiki/Categorical_variable" title="Categorical variable">Categorical</a> / <a href="/wiki/Multivariate_statistics" title="Multivariate statistics">Multivariate</a> / <a href="/wiki/Time_series" title="Time series">Time-series</a> / <a href="/wiki/Survival_analysis" title="Survival analysis">Survival analysis</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Categorical_variable" title="Categorical variable">Categorical</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cohen%27s_kappa" title="Cohen's kappa">Cohen's kappa</a></li> <li><a href="/wiki/Contingency_table" title="Contingency table">Contingency table</a></li> <li><a href="/wiki/Graphical_model" title="Graphical model">Graphical model</a></li> <li><a href="/wiki/Poisson_regression" title="Poisson regression">Log-linear model</a></li> <li><a href="/wiki/McNemar%27s_test" title="McNemar's test">McNemar's test</a></li> <li><a href="/wiki/Cochran%E2%80%93Mantel%E2%80%93Haenszel_statistics" title="Cochran–Mantel–Haenszel statistics">Cochran–Mantel–Haenszel statistics</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Multivariate_statistics" title="Multivariate statistics">Multivariate</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/General_linear_model" title="General linear model">Regression</a></li> <li><a href="/wiki/Multivariate_analysis_of_variance" title="Multivariate analysis of variance">Manova</a></li> <li><a href="/wiki/Principal_component_analysis" title="Principal component analysis">Principal components</a></li> <li><a href="/wiki/Canonical_correlation" title="Canonical correlation">Canonical correlation</a></li> <li><a href="/wiki/Linear_discriminant_analysis" title="Linear discriminant analysis">Discriminant analysis</a></li> <li><a href="/wiki/Cluster_analysis" title="Cluster analysis">Cluster analysis</a></li> <li><a href="/wiki/Statistical_classification" title="Statistical classification">Classification</a></li> <li><a href="/wiki/Structural_equation_modeling" title="Structural equation modeling">Structural equation model</a> <ul><li><a href="/wiki/Factor_analysis" title="Factor analysis">Factor analysis</a></li></ul></li> <li><a href="/wiki/Multivariate_distribution" class="mw-redirect" title="Multivariate distribution">Multivariate distributions</a> <ul><li><a href="/wiki/Elliptical_distribution" title="Elliptical distribution">Elliptical distributions</a> <ul><li><a href="/wiki/Multivariate_normal_distribution" title="Multivariate normal distribution">Normal</a></li></ul></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Time_series" title="Time series">Time-series</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;">General</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Decomposition_of_time_series" title="Decomposition of time series">Decomposition</a></li> <li><a href="/wiki/Trend_estimation" class="mw-redirect" title="Trend estimation">Trend</a></li> <li><a href="/wiki/Stationary_process" title="Stationary process">Stationarity</a></li> <li><a href="/wiki/Seasonal_adjustment" title="Seasonal adjustment">Seasonal adjustment</a></li> <li><a href="/wiki/Exponential_smoothing" title="Exponential smoothing">Exponential smoothing</a></li> <li><a href="/wiki/Cointegration" title="Cointegration">Cointegration</a></li> <li><a href="/wiki/Structural_break" title="Structural break">Structural break</a></li> <li><a href="/wiki/Granger_causality" title="Granger causality">Granger causality</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;">Specific tests</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Dickey%E2%80%93Fuller_test" title="Dickey–Fuller test">Dickey–Fuller</a></li> <li><a href="/wiki/Johansen_test" title="Johansen test">Johansen</a></li> <li><a href="/wiki/Ljung%E2%80%93Box_test" title="Ljung–Box test">Q-statistic <span style="font-size:85%;">(Ljung–Box)</span></a></li> <li><a href="/wiki/Durbin%E2%80%93Watson_statistic" title="Durbin–Watson statistic">Durbin–Watson</a></li> <li><a href="/wiki/Breusch%E2%80%93Godfrey_test" title="Breusch–Godfrey test">Breusch–Godfrey</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;"><a href="/wiki/Time_domain" title="Time domain">Time domain</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Autocorrelation" title="Autocorrelation">Autocorrelation (ACF)</a> <ul><li><a href="/wiki/Partial_autocorrelation_function" title="Partial autocorrelation function">partial (PACF)</a></li></ul></li> <li><a href="/wiki/Cross-correlation" title="Cross-correlation">Cross-correlation (XCF)</a></li> <li><a href="/wiki/Autoregressive%E2%80%93moving-average_model" class="mw-redirect" title="Autoregressive–moving-average model">ARMA model</a></li> <li><a href="/wiki/Box%E2%80%93Jenkins_method" title="Box–Jenkins method">ARIMA model <span style="font-size:85%;">(Box–Jenkins)</span></a></li> <li><a href="/wiki/Autoregressive_conditional_heteroskedasticity" title="Autoregressive conditional heteroskedasticity">Autoregressive conditional heteroskedasticity (ARCH)</a></li> <li><a href="/wiki/Vector_autoregression" title="Vector autoregression">Vector autoregression (VAR)</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;"><a href="/wiki/Frequency_domain" title="Frequency domain">Frequency domain</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Spectral_density_estimation" title="Spectral density estimation">Spectral density estimation</a></li> <li><a href="/wiki/Fourier_analysis" title="Fourier analysis">Fourier analysis</a></li> <li><a href="/wiki/Least-squares_spectral_analysis" title="Least-squares spectral analysis">Least-squares spectral analysis</a></li> <li><a href="/wiki/Wavelet" title="Wavelet">Wavelet</a></li> <li><a href="/wiki/Whittle_likelihood" title="Whittle likelihood">Whittle likelihood</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Survival_analysis" title="Survival analysis">Survival</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;"><a href="/wiki/Survival_function" title="Survival function">Survival function</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Kaplan%E2%80%93Meier_estimator" title="Kaplan–Meier estimator">Kaplan–Meier estimator (product limit)</a></li> <li><a href="/wiki/Proportional_hazards_model" title="Proportional hazards model">Proportional hazards models</a></li> <li><a href="/wiki/Accelerated_failure_time_model" title="Accelerated failure time model">Accelerated failure time (AFT) model</a></li> <li><a href="/wiki/First-hitting-time_model" title="First-hitting-time model">First hitting time</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;"><a href="/wiki/Failure_rate" title="Failure rate">Hazard function</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Nelson%E2%80%93Aalen_estimator" title="Nelson–Aalen estimator">Nelson–Aalen estimator</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;">Test</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Log-rank_test" class="mw-redirect" title="Log-rank test">Log-rank test</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible uncollapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div id="Applications636" style="font-size:114%;margin:0 4em"><a href="/wiki/List_of_fields_of_application_of_statistics" title="List of fields of application of statistics">Applications</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Biostatistics" title="Biostatistics">Biostatistics</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Bioinformatics" title="Bioinformatics">Bioinformatics</a></li> <li><a href="/wiki/Clinical_trial" title="Clinical trial">Clinical trials</a> / <a href="/wiki/Clinical_study_design" title="Clinical study design">studies</a></li> <li><a class="mw-selflink selflink">Epidemiology</a></li> <li><a href="/wiki/Medical_statistics" title="Medical statistics">Medical statistics</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Engineering_statistics" title="Engineering statistics">Engineering statistics</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Chemometrics" title="Chemometrics">Chemometrics</a></li> <li><a href="/wiki/Methods_engineering" title="Methods engineering">Methods engineering</a></li> <li><a href="/wiki/Probabilistic_design" title="Probabilistic design">Probabilistic design</a></li> <li><a href="/wiki/Statistical_process_control" title="Statistical process control">Process</a> / <a href="/wiki/Quality_control" title="Quality control">quality control</a></li> <li><a href="/wiki/Reliability_engineering" title="Reliability engineering">Reliability</a></li> <li><a href="/wiki/System_identification" title="System identification">System identification</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Social_statistics" title="Social statistics">Social statistics</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Actuarial_science" title="Actuarial science">Actuarial science</a></li> <li><a href="/wiki/Census" title="Census">Census</a></li> <li><a href="/wiki/Crime_statistics" title="Crime statistics">Crime statistics</a></li> <li><a href="/wiki/Demographic_statistics" title="Demographic statistics">Demography</a></li> <li><a href="/wiki/Econometrics" title="Econometrics">Econometrics</a></li> <li><a href="/wiki/Jurimetrics" title="Jurimetrics">Jurimetrics</a></li> <li><a href="/wiki/National_accounts" title="National accounts">National accounts</a></li> <li><a href="/wiki/Official_statistics" title="Official statistics">Official statistics</a></li> <li><a href="/wiki/Population_statistics" class="mw-redirect" title="Population statistics">Population statistics</a></li> <li><a href="/wiki/Psychometrics" title="Psychometrics">Psychometrics</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12.5em"><a href="/wiki/Spatial_analysis" title="Spatial analysis">Spatial statistics</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cartography" title="Cartography">Cartography</a></li> <li><a href="/wiki/Environmental_statistics" title="Environmental statistics">Environmental statistics</a></li> <li><a href="/wiki/Geographic_information_system" title="Geographic information system">Geographic information system</a></li> <li><a href="/wiki/Geostatistics" title="Geostatistics">Geostatistics</a></li> <li><a href="/wiki/Kriging" title="Kriging">Kriging</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <ul><li><span class="noviewer" typeof="mw:File"><span title="Category"><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/16px-Symbol_category_class.svg.png" decoding="async" width="16" height="16" class="mw-file-element" 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style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Epidemiology" title="Template:Epidemiology"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Epidemiology" title="Template talk:Epidemiology"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Epidemiology" title="Special:EditPage/Template:Epidemiology"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Topics_in_epidemiology71" style="font-size:114%;margin:0 4em">Topics in <a class="mw-selflink selflink">epidemiology</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Branches of epidemiology</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;">by physiology/disease:</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cognitive_epidemiology" title="Cognitive epidemiology">Cognitive epidemiology</a></li> <li><a href="/wiki/Neuroepidemiology" title="Neuroepidemiology">Neuroepidemiology</a></li> <li><a href="/wiki/Psychiatric_epidemiology" title="Psychiatric epidemiology">Psychiatric epidemiology</a></li> <li><a href="/wiki/Epizootiology" title="Epizootiology">Veterinary epidemiology</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;">by methodological approach:</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Biostatistics" title="Biostatistics">Biostatistics</a></li> <li><a href="/wiki/Disease_informatics" title="Disease informatics">Disease informatics</a></li> <li><a href="/wiki/E-epidemiology" title="E-epidemiology">E-epidemiology</a></li> <li><a href="/wiki/Environmental_epidemiology" title="Environmental epidemiology">Environmental epidemiology</a></li> <li><a href="/wiki/Economic_epidemiology" title="Economic epidemiology">Economic epidemiology</a></li> <li><a href="/wiki/Clinical_epidemiology" title="Clinical epidemiology">Clinical epidemiology</a></li> <li><a href="/wiki/Computational_epidemiology" title="Computational epidemiology">Computational epidemiology</a></li> <li><a href="/wiki/Conflict_epidemiology" title="Conflict epidemiology">Conflict epidemiology</a></li> <li><a href="/wiki/Genetic_epidemiology" title="Genetic epidemiology">Genetic epidemiology</a></li> <li><a href="/wiki/Life_course_approach" title="Life course approach">Life course approach</a></li> <li><a href="/wiki/Meta-analysis" title="Meta-analysis">Meta-analysis</a></li> <li><a href="/wiki/Molecular_epidemiology" title="Molecular epidemiology">Molecular epidemiology</a></li> <li><a href="/wiki/Molecular_pathological_epidemiology" title="Molecular pathological epidemiology">Molecular pathological epidemiology</a></li> <li><a href="/wiki/Nutritional_epidemiology" title="Nutritional epidemiology">Nutritional epidemiology</a></li> <li><a href="/wiki/Paleoepidemiology" class="mw-redirect" title="Paleoepidemiology">Paleoepidemiology</a></li> <li><a href="/wiki/Pharmacoepidemiology" title="Pharmacoepidemiology">Pharmacoepidemiology</a></li> <li><a href="/wiki/Social_epidemiology" title="Social epidemiology">Social epidemiology</a></li> <li><a href="/wiki/Spatial_epidemiology" title="Spatial epidemiology">Spatial epidemiology</a></li> <li><a href="/wiki/Tele-epidemiology" title="Tele-epidemiology">Tele-epidemiology</a></li> <li><a href="/wiki/Surveillance" title="Surveillance">Surveillance</a> epidemiology (<a href="/wiki/Clinical_surveillance" class="mw-redirect" title="Clinical surveillance">Clinical surveillance</a>)</li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Epidemiology journals</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;">General</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/American_Journal_of_Epidemiology" title="American Journal of Epidemiology">American Journal of Epidemiology</a></li> <li><a rel="nofollow" class="external text" href="http://www.cjeb.ca/">Canadian Journal of Epidemiology and Biostatistics</a></li> <li><a rel="nofollow" class="external text" href="http://www.epidemiologicalnews.com">Global Epidemiological News</a></li> <li><a rel="nofollow" class="external text" href="http://epirev.oxfordjournals.org">Epidemiologic Reviews</a></li> <li><a href="/wiki/Epidemiology_(journal)" title="Epidemiology (journal)">Epidemiology</a></li> <li><a href="/wiki/International_Journal_of_Epidemiology" title="International Journal of Epidemiology">International Journal of Epidemiology</a></li> <li><a href="/wiki/Annals_of_Epidemiology" title="Annals of Epidemiology">Annals of Epidemiology</a></li> <li><a rel="nofollow" class="external text" href="http://jech.bmj.com">Journal of Epidemiology and Community Health</a></li> <li><a href="/wiki/European_Journal_of_Epidemiology" title="European Journal of Epidemiology">European Journal of Epidemiology</a></li> <li><a href="/wiki/Emerging_Themes_in_Epidemiology" title="Emerging Themes in Epidemiology">Emerging Themes in Epidemiology</a></li> <li><a rel="nofollow" class="external text" href="http://www.epi-perspectives.com">Epidemiologic Perspectives and Innovations</a></li> <li><a rel="nofollow" class="external text" href="http://www.eurosurveillance.org">Eurosurveillance</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;">Speciality</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cancer_Causes_%26_Control" title="Cancer Causes & Control">Cancer Causes & Control</a></li> <li><a rel="nofollow" class="external text" href="http://cebp.aacrjournals.org">Cancer Epidemiology Biomarkers and Prevention</a></li> <li><a href="/wiki/Epidemiology_and_Infection" title="Epidemiology and Infection">Epidemiology and Infection</a></li> <li><a href="/wiki/Genetic_Epidemiology_(journal)" title="Genetic Epidemiology (journal)">Genetic Epidemiology</a></li> <li><a rel="nofollow" class="external text" href="https://www.jstor.org/action/showPublication?journalCode=infeconthospepid">Infection Control and Hospital Epidemiology</a></li> <li><a href="/wiki/Journal_of_Clinical_Epidemiology" title="Journal of Clinical Epidemiology">Journal of Clinical Epidemiology</a></li> <li><a rel="nofollow" class="external text" href="http://www.blackwellpublishing.com/journal.asp?ref=0269-5022">Paediatric Perinatal Epidemiology</a></li> <li><a rel="nofollow" class="external text" href="http://eu.wiley.com/WileyCDA/WileyTitle/productCd-PDS.html">Pharmacoepidemiology and Drug Safety</a></li> <li><a href="/wiki/Preventive_Medicine_(journal)" title="Preventive Medicine (journal)">Preventive Medicine</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link 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class="uid"><span class="rt-commentedText tooltip tooltip-dotted" title="Épidémiologie"><a rel="nofollow" class="external text" href="https://catalogue.bnf.fr/ark:/12148/cb11971166r">France</a></span></span></li><li><span class="uid"><span class="rt-commentedText tooltip tooltip-dotted" title="Épidémiologie"><a rel="nofollow" class="external text" href="https://data.bnf.fr/ark:/12148/cb11971166r">BnF data</a></span></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="https://id.ndl.go.jp/auth/ndlna/00561888">Japan</a></span></li><li><span class="uid"><span class="rt-commentedText tooltip tooltip-dotted" title="epidemiologie"><a rel="nofollow" class="external text" href="https://aleph.nkp.cz/F/?func=find-c&local_base=aut&ccl_term=ica=ph114481&CON_LNG=ENG">Czech Republic</a></span></span></li><li><span class="uid"><span class="rt-commentedText tooltip tooltip-dotted" title="Epidemiología"><a rel="nofollow" class="external text" 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