Search results for: Anchusa azurea

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azurea</title> <meta name="description" content="Search results for: Anchusa azurea"> <meta name="keywords" content="Anchusa azurea"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler 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id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Anchusa azurea"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 3</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Anchusa azurea</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> β-Lactamase Inhibitory Effects of Anchusa azurea Extracts</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Naoual%20Boussoualim">Naoual Boussoualim</a>, <a href="https://publications.waset.org/abstracts/search?q=Hayat%20Trabsa"> Hayat Trabsa</a>, <a href="https://publications.waset.org/abstracts/search?q=Iman%20Krache"> Iman Krache</a>, <a href="https://publications.waset.org/abstracts/search?q=Lekhmici%20Arrar"> Lekhmici Arrar</a>, <a href="https://publications.waset.org/abstracts/search?q=Abderrahmane%20Baghiani"> Abderrahmane Baghiani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Resistance to antibiotics has emerged following their widespread use; the important mechanism of beta-lactam resistance in bacteria is the production of beta-lactamase. In order to find new bioactive beta-lactamase inhibitors, this study investigated the inhibition effect of the extracts of Anchusa azurea (AA) on a beta-lactamase from Bacillus cereus. The extracts exerted inhibitory effects on beta-lactamase in a dose-dependent manner, the results showed that the crude extract (BrE) and the ethyl acetate extract (AcE) of Anchusa azurea showed a very high inhibitory activity at a concentration of 10 mg, the percentage of inhibition was between 58% and 68%. Not all extracts were as potent as the original inhibitors such as clavulanic acid, the isolation and the structural elucidation of the active constituents in these extracts will provide useful means in the development of beta -lactamase inhibitors. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anchusa%20azurea" title="Anchusa azurea">Anchusa azurea</a>, <a href="https://publications.waset.org/abstracts/search?q=natural%20product" title=" natural product"> natural product</a>, <a href="https://publications.waset.org/abstracts/search?q=resistance" title=" resistance"> resistance</a>, <a href="https://publications.waset.org/abstracts/search?q=antibiotics" title=" antibiotics"> antibiotics</a>, <a href="https://publications.waset.org/abstracts/search?q=beta-lactamase" title=" beta-lactamase"> beta-lactamase</a>, <a href="https://publications.waset.org/abstracts/search?q=inhibitors" title=" inhibitors"> inhibitors</a> </p> <a href="https://publications.waset.org/abstracts/41796/v-lactamase-inhibitory-effects-of-anchusa-azurea-extracts" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41796.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">511</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Biologically Active Caffeic Acid-Derived Biopolymer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=V.%20Barbakadze">V. Barbakadze</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20Gogilashvili"> L. Gogilashvili</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20Amiranashvili"> L. Amiranashvili</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Merlani"> M. Merlani</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20Mulkijanyan"> K. Mulkijanyan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The high-molecular water-soluble preparations from several species of two genera (Symphytum and Anchusa) of Boraginaceae family Symphytum asperum, S. caucasicum, S.officinale and Anchusa italica were isolated. According to IR, 13C and 1H NMR, APT, 1D NOE, 2D heteronuclear 1H/13C HSQC and 2D DOSY experiments, the main chemical constit¬uent of these preparations was found to be caffeic acid-derived polyether, namely poly[3-(3,4-dihydroxyphenyl)glyceric acid] (PDPGA) or poly[oxy-1-carboxy-2-(3,4-dihydroxyphenyl)ethylene]. Most carboxylic groups of this caffeic acid-derived polymer of A. italica are methylated. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anchusa" title="Anchusa">Anchusa</a>, <a href="https://publications.waset.org/abstracts/search?q=poly%5B3-%283" title=" poly[3-(3"> poly[3-(3</a>, <a href="https://publications.waset.org/abstracts/search?q=4-dihydroxyphenyl%29glyceric%20acid%5D" title="4-dihydroxyphenyl)glyceric acid]">4-dihydroxyphenyl)glyceric acid]</a>, <a href="https://publications.waset.org/abstracts/search?q=poly%5Boxy-1-carboxy-2-%283" title=" poly[oxy-1-carboxy-2-(3"> poly[oxy-1-carboxy-2-(3</a>, <a href="https://publications.waset.org/abstracts/search?q=4-dihydroxyphenyl%29ethylene%5D" title="4-dihydroxyphenyl)ethylene]">4-dihydroxyphenyl)ethylene]</a>, <a href="https://publications.waset.org/abstracts/search?q=Symphytum" title=" Symphytum"> Symphytum</a> </p> <a href="https://publications.waset.org/abstracts/1643/biologically-active-caffeic-acid-derived-biopolymer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/1643.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">329</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Novel Phenolic Biopolyether with Potential Therapeutic Effect</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=V.Barbakadze">V.Barbakadze</a>, <a href="https://publications.waset.org/abstracts/search?q=L.Gogilashvili"> L.Gogilashvili</a>, <a href="https://publications.waset.org/abstracts/search?q=L.Amiranashvili"> L.Amiranashvili</a>, <a href="https://publications.waset.org/abstracts/search?q=M.Merlani"> M.Merlani</a>, <a href="https://publications.waset.org/abstracts/search?q=K.Mulkijanyan"> K.Mulkijanyan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The high-molecular fractions from the several species of two genera (Symphytum and Anchusa) of Boraginaceae family Symphytum asperum, S. caucasicum, S. officinale, and Anchusa italica were isolated. According to IR, 13C and 1H NMR, 2D heteronuclear 1H/13C HSQC spectral data and 1D NOE experiment, the main structural element of these preparations was found to be a regularly substituted polyoxyethylene, namely poly[3-(3,4-dihydroxyenyl)glyceric acid] (PDPGA) or poly[oxy-1-carboxy-2-(3,4-dihydroxyphenyl)ethylene]. Such caffeic acid-derived biopolymer to our knowledge has not been known and has been identified for the first time. This compound represents a new class of natural polyethers with a residue of 3-(3,4-dihydroxyphenyl)glyceric acid as the repeating unit. Most of the carboxylic groups of PDPGA from A. italica unlike the polymer of S. asperum, S. caucasicum, and S. officinale are methylated. The 2D DOSY experiment gave the similar diffusion coefficient for the methylated and non-methylated signals of A. italica PDPGA. Both sets of signals fell in the same horizontal. This would imply a similar molecular weight for methylated and non-methylated polymers. This was further evidenced by graphic representations of the intensity decay of the 1H signals of aromatic H-2″ and H-1 at δ 7.16 and 5.24 and that of the methoxy group at δ 3.85. These three signals essentially showed the same curve shape. According to results of in vitro and in vivo experiments PDPGA of S.asperum and S.caucasicum could be considered as potential anti-inflammatory, wound healing and anti-cancer therapeutic agent. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=caffeic%20acid-derived%20%20polyether" title="caffeic acid-derived polyether">caffeic acid-derived polyether</a>, <a href="https://publications.waset.org/abstracts/search?q=poly%5B3-%283" title=" poly[3-(3"> poly[3-(3</a>, <a href="https://publications.waset.org/abstracts/search?q=4-dihydroxyphenyl%29glyceric%20acid%5D" title="4-dihydroxyphenyl)glyceric acid]">4-dihydroxyphenyl)glyceric acid]</a>, <a href="https://publications.waset.org/abstracts/search?q=poly%5Boxy-1-carboxy-2-%283" title=" poly[oxy-1-carboxy-2-(3"> poly[oxy-1-carboxy-2-(3</a>, <a href="https://publications.waset.org/abstracts/search?q=4-dihydroxyphenyl%29ethylene%5D" title="4-dihydroxyphenyl)ethylene]">4-dihydroxyphenyl)ethylene]</a>, <a href="https://publications.waset.org/abstracts/search?q=symphytum" title=" symphytum"> symphytum</a>, <a href="https://publications.waset.org/abstracts/search?q=anchusa" title=" anchusa"> anchusa</a> </p> <a href="https://publications.waset.org/abstracts/1619/novel-phenolic-biopolyether-with-potential-therapeutic-effect" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/1619.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">403</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a 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Search results for: Anchusa azurea