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</header> <section id="content" class="site-content"> <div class="container"> <div class="row"> <div id="primary" class="content-area col-md-8"> <main id="main" class="site-main" role="main"> <header class="page-header"> <h1 class="page-title">Category: <span>Nephrology</span></h1><div class="taxonomy-description"><p>Specialty: Nephrology</p> </div> </header> <article id="post-7912" class="post-7912 post type-post status-publish format-standard has-post-thumbnail hentry category-diabetes-endocrinology category-gastroenterology-gi-surgery category-nephrology"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2024/08/29/study-finds-90-of-adults-have-stage-1-or-higher-ckm-syndrome/" rel="bookmark">Study Finds 90% of Adults Have Stage 1 or Higher CKM Syndrome</a></h1> <div class="entry-thumbnail"> <img width="300" height="225" src="https://www.brighamhealthonamission.org/wp-content/uploads/2024/08/cardiovascular-kidney-me-6.jpg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="" decoding="async" fetchpriority="high" /> </div> </header>  <div class="entry-summary"> <p>A Brigham and Women’s Hospital research team established baseline epidemiological information about a new paradigm called cardiovascular, kidney, and metabolic (CKM) syndrome.</p> <a href="https://www.brighamhealthonamission.org/2024/08/29/study-finds-90-of-adults-have-stage-1-or-higher-ckm-syndrome/" class="more-link">Read More...</a><div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-7912" class="share-linkedin sd-button share-icon no-text" 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href="mailto:?subject=%5BShared%20Post%5D%20Study%20Finds%2090%25%20of%20Adults%20Have%20Stage%201%20or%20Higher%20CKM%20Syndrome&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2024%2F08%2F29%2Fstudy-finds-90-of-adults-have-stage-1-or-higher-ckm-syndrome%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="b314a9b01f" data-email-share-track-url="https://www.brighamhealthonamission.org/2024/08/29/study-finds-90-of-adults-have-stage-1-or-higher-ckm-syndrome/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-7461" class="post-7461 post type-post status-publish format-standard has-post-thumbnail hentry category-cardiology-heart category-nephrology"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2023/12/28/initial-decline-in-egfr-with-dapagliflozin-not-concerning-in-patients-with-heart-failure-and-lvef-40/" rel="bookmark">Initial Decline in eGFR With Dapagliflozin Not Concerning in Patients With Heart Failure and LVEF >40%</a></h1> <div class="entry-thumbnail"> <img width="300" height="225" src="https://www.brighamhealthonamission.org/wp-content/uploads/2024/01/chronic-kidney-disease-d.jpg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="" decoding="async" /> </div> </header>  <div class="entry-summary"> <p>Brigham and Women’s Hospital researchers report an initial decline in estimated glomerular filtration rate (eGFR) on initiation of dapagliflozin was not associated with adverse cardiovascular or kidney outcomes and did not appear to alter the long-term trajectory of eGFR decline.</p> <a href="https://www.brighamhealthonamission.org/2023/12/28/initial-decline-in-egfr-with-dapagliflozin-not-concerning-in-patients-with-heart-failure-and-lvef-40/" class="more-link">Read More...</a><div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-7461" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2023/12/28/initial-decline-in-egfr-with-dapagliflozin-not-concerning-in-patients-with-heart-failure-and-lvef-40/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-7461" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2023/12/28/initial-decline-in-egfr-with-dapagliflozin-not-concerning-in-patients-with-heart-failure-and-lvef-40/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-7461" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2023/12/28/initial-decline-in-egfr-with-dapagliflozin-not-concerning-in-patients-with-heart-failure-and-lvef-40/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2023/12/28/initial-decline-in-egfr-with-dapagliflozin-not-concerning-in-patients-with-heart-failure-and-lvef-40/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20Initial%20Decline%20in%20eGFR%20With%20Dapagliflozin%20Not%20Concerning%20in%20Patients%20With%20Heart%20Failure%20and%20LVEF%20%3E40%25&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2023%2F12%2F28%2Finitial-decline-in-egfr-with-dapagliflozin-not-concerning-in-patients-with-heart-failure-and-lvef-40%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="1eb72fb533" data-email-share-track-url="https://www.brighamhealthonamission.org/2023/12/28/initial-decline-in-egfr-with-dapagliflozin-not-concerning-in-patients-with-heart-failure-and-lvef-40/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-6931" class="post-6931 post type-post status-publish format-standard hentry category-cancer category-diabetes-endocrinology category-nephrology"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2023/03/24/stark-differences-found-in-hospital-level-patterns-of-nonoperative-management-for-low-risk-thyroid-and-kidney-cancers/" rel="bookmark">Stark Differences Found in Hospital-level Patterns of Nonoperative Management for Low-risk Thyroid and Kidney Cancers</a></h1> </header> <div class="entry-summary"> <p><img decoding="async" class="alignnone size-medium wp-image-6933 aligncenter" src="https://www.brighamhealthonamission.org/wp-content/uploads/2023/03/ACole-300x300.jpg" alt="" width="300" height="300" srcset="https://www.brighamhealthonamission.org/wp-content/uploads/2023/03/ACole-300x300.jpg 300w, https://www.brighamhealthonamission.org/wp-content/uploads/2023/03/ACole-150x150.jpg 150w, https://www.brighamhealthonamission.org/wp-content/uploads/2023/03/ACole-500x500.jpg 500w, https://www.brighamhealthonamission.org/wp-content/uploads/2023/03/ACole.jpg 600w" sizes="(max-width: 300px) 100vw, 300px" /></p> <p>A growing set of low-risk cancers, including early-stage thyroid and kidney cancers, is associated with excellent outcomes regardless of management strategy. Given the risks associated with overtreatment of these cancers, it follows that many patients should be treated nonoperatively. <a href="https://www.brighamhealthonamission.org/2023/03/24/stark-differences-found-in-hospital-level-patterns-of-nonoperative-management-for-low-risk-thyroid-and-kidney-cancers/#more-6931" class="more-link">Read More</a></p> <div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-6931" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2023/03/24/stark-differences-found-in-hospital-level-patterns-of-nonoperative-management-for-low-risk-thyroid-and-kidney-cancers/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-6931" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2023/03/24/stark-differences-found-in-hospital-level-patterns-of-nonoperative-management-for-low-risk-thyroid-and-kidney-cancers/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-6931" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2023/03/24/stark-differences-found-in-hospital-level-patterns-of-nonoperative-management-for-low-risk-thyroid-and-kidney-cancers/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2023/03/24/stark-differences-found-in-hospital-level-patterns-of-nonoperative-management-for-low-risk-thyroid-and-kidney-cancers/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20Stark%20Differences%20Found%20in%20Hospital-level%20Patterns%20of%20Nonoperative%20Management%20for%20Low-risk%20Thyroid%20and%20Kidney%20Cancers&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2023%2F03%2F24%2Fstark-differences-found-in-hospital-level-patterns-of-nonoperative-management-for-low-risk-thyroid-and-kidney-cancers%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="22394a7831" data-email-share-track-url="https://www.brighamhealthonamission.org/2023/03/24/stark-differences-found-in-hospital-level-patterns-of-nonoperative-management-for-low-risk-thyroid-and-kidney-cancers/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-6572" class="post-6572 post type-post status-publish format-standard has-post-thumbnail hentry category-nephrology category-urology"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2022/11/09/brigham-researchers-develop-efficient-method-to-generate-ureteric-bud-first-human-functional-collecting-duct-principal-and-intercalated-cells/" rel="bookmark">Brigham Researchers Develop Efficient Method to Generate Ureteric Bud, First Human Functional Collecting Duct Principal and Intercalated Cells</a></h1> <div class="entry-thumbnail"> <img width="300" height="225" src="https://www.brighamhealthonamission.org/wp-content/uploads/2022/11/at-doctors-appointment-p.jpg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="Doctor holds anatomical model of a human kidney, pointing to it while seated at desk" decoding="async" loading="lazy" /> </div> </header>  <div class="entry-summary"> <p>Creating kidney organoids for preclinical research poses a challenge due to their complex architecture. Brigham researchers have developed an efficient method for generating functional ureteric bud and collecting ducts organoids, which drive the growth and radial organization of the developing kidney.</p> <a href="https://www.brighamhealthonamission.org/2022/11/09/brigham-researchers-develop-efficient-method-to-generate-ureteric-bud-first-human-functional-collecting-duct-principal-and-intercalated-cells/" class="more-link">Read More...</a><div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-6572" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2022/11/09/brigham-researchers-develop-efficient-method-to-generate-ureteric-bud-first-human-functional-collecting-duct-principal-and-intercalated-cells/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-6572" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2022/11/09/brigham-researchers-develop-efficient-method-to-generate-ureteric-bud-first-human-functional-collecting-duct-principal-and-intercalated-cells/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-6572" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2022/11/09/brigham-researchers-develop-efficient-method-to-generate-ureteric-bud-first-human-functional-collecting-duct-principal-and-intercalated-cells/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2022/11/09/brigham-researchers-develop-efficient-method-to-generate-ureteric-bud-first-human-functional-collecting-duct-principal-and-intercalated-cells/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20Brigham%20Researchers%20Develop%20Efficient%20Method%20to%20Generate%20Ureteric%20Bud%2C%20First%20Human%20Functional%20Collecting%20Duct%20Principal%20and%20Intercalated%20Cells&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2022%2F11%2F09%2Fbrigham-researchers-develop-efficient-method-to-generate-ureteric-bud-first-human-functional-collecting-duct-principal-and-intercalated-cells%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="849a4e6e36" data-email-share-track-url="https://www.brighamhealthonamission.org/2022/11/09/brigham-researchers-develop-efficient-method-to-generate-ureteric-bud-first-human-functional-collecting-duct-principal-and-intercalated-cells/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-5447" class="post-5447 post type-post status-publish format-standard hentry category-cancer category-nephrology"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2021/02/03/studying-new-approaches-for-immunotherapy-in-renal-cancer/" rel="bookmark">Studying New Approaches for Immunotherapy in Renal Cancer</a></h1> </header> <div class="entry-summary"> <p><img loading="lazy" decoding="async" class="aligncenter size-medium wp-image-5448" src="https://www.brighamhealthonamission.org/wp-content/uploads/2021/02/immunotherapy-renal-cancer.jpg-300x200.png" alt="illustration of organ" width="300" height="200" srcset="https://www.brighamhealthonamission.org/wp-content/uploads/2021/02/immunotherapy-renal-cancer.jpg-300x200.png 300w, https://www.brighamhealthonamission.org/wp-content/uploads/2021/02/immunotherapy-renal-cancer.jpg-1024x683.png 1024w, https://www.brighamhealthonamission.org/wp-content/uploads/2021/02/immunotherapy-renal-cancer.jpg-768x512.png 768w, https://www.brighamhealthonamission.org/wp-content/uploads/2021/02/immunotherapy-renal-cancer.jpg-750x500.png 750w, https://www.brighamhealthonamission.org/wp-content/uploads/2021/02/immunotherapy-renal-cancer.jpg.png 1200w" sizes="auto, (max-width: 300px) 100vw, 300px" /></p> <p>Immunotherapy with checkpoint inhibitor drugs is an emerging treatment for renal cell carcinoma. Now investigators from Brigham and Women’s Hospital have reported the results from lab research looking at a potential new way to boost the immune system’s ability to fight cancer.</p> <p> <a href="https://www.brighamhealthonamission.org/2021/02/03/studying-new-approaches-for-immunotherapy-in-renal-cancer/#more-5447" class="more-link">Read More</a></p> <div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-5447" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2021/02/03/studying-new-approaches-for-immunotherapy-in-renal-cancer/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-5447" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2021/02/03/studying-new-approaches-for-immunotherapy-in-renal-cancer/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-5447" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2021/02/03/studying-new-approaches-for-immunotherapy-in-renal-cancer/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2021/02/03/studying-new-approaches-for-immunotherapy-in-renal-cancer/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20Studying%20New%20Approaches%20for%20Immunotherapy%20in%20Renal%20Cancer&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2021%2F02%2F03%2Fstudying-new-approaches-for-immunotherapy-in-renal-cancer%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="ba93d844c2" data-email-share-track-url="https://www.brighamhealthonamission.org/2021/02/03/studying-new-approaches-for-immunotherapy-in-renal-cancer/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-5384" class="post-5384 post type-post status-publish format-standard hentry category-cancer category-nephrology"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2021/01/21/using-nanoparticles-to-target-renal-cell-carcinoma/" rel="bookmark">Using Nanoparticles to Target Renal Cell Carcinoma</a></h1> </header> <div class="entry-summary"> <p><img loading="lazy" decoding="async" class="aligncenter size-medium wp-image-5380" src="https://www.brighamhealthonamission.org/wp-content/uploads/2021/01/nanoparticles-blog-300x199.jpg" alt="nanoparticles" width="300" height="199" srcset="https://www.brighamhealthonamission.org/wp-content/uploads/2021/01/nanoparticles-blog-300x199.jpg 300w, https://www.brighamhealthonamission.org/wp-content/uploads/2021/01/nanoparticles-blog-1024x678.jpg 1024w, https://www.brighamhealthonamission.org/wp-content/uploads/2021/01/nanoparticles-blog-768x508.jpg 768w, https://www.brighamhealthonamission.org/wp-content/uploads/2021/01/nanoparticles-blog-750x500.jpg 750w, https://www.brighamhealthonamission.org/wp-content/uploads/2021/01/nanoparticles-blog-756x500.jpg 756w, https://www.brighamhealthonamission.org/wp-content/uploads/2021/01/nanoparticles-blog.jpg 1200w" sizes="auto, (max-width: 300px) 100vw, 300px" />Targeted therapy has had much less success in treating renal cell carcinoma than in treating many other kinds of cancer. Physician-scientists at Brigham and Women’s Hospital are working on several innovative approaches to address this shortfall.</p> <p> <a href="https://www.brighamhealthonamission.org/2021/01/21/using-nanoparticles-to-target-renal-cell-carcinoma/#more-5384" class="more-link">Read More</a></p> <div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-5384" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2021/01/21/using-nanoparticles-to-target-renal-cell-carcinoma/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-5384" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2021/01/21/using-nanoparticles-to-target-renal-cell-carcinoma/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-5384" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2021/01/21/using-nanoparticles-to-target-renal-cell-carcinoma/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2021/01/21/using-nanoparticles-to-target-renal-cell-carcinoma/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20Using%20Nanoparticles%20to%20Target%20Renal%20Cell%20Carcinoma&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2021%2F01%2F21%2Fusing-nanoparticles-to-target-renal-cell-carcinoma%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="9279ebfa9c" data-email-share-track-url="https://www.brighamhealthonamission.org/2021/01/21/using-nanoparticles-to-target-renal-cell-carcinoma/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-5159" class="post-5159 post type-post status-publish format-standard hentry category-covid-19 category-nephrology"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2020/11/12/uncovering-risks-for-severe-aki-in-covid-19-patients/" rel="bookmark">Uncovering Risks for Severe AKI in COVID-19 Patients</a></h1> </header> <div class="entry-summary"> <p><img loading="lazy" decoding="async" class="size-medium wp-image-5155 aligncenter" src="https://www.brighamhealthonamission.org/wp-content/uploads/2020/11/neph-AKI-feature-300x200.jpg" alt="Dialysis machine" width="300" height="200" srcset="https://www.brighamhealthonamission.org/wp-content/uploads/2020/11/neph-AKI-feature-300x200.jpg 300w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/11/neph-AKI-feature-1024x683.jpg 1024w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/11/neph-AKI-feature-768x512.jpg 768w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/11/neph-AKI-feature-1536x1024.jpg 1536w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/11/neph-AKI-feature-2048x1365.jpg 2048w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/11/neph-AKI-feature-1200x800.jpg 1200w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/11/neph-AKI-feature-750x500.jpg 750w" sizes="auto, (max-width: 300px) 100vw, 300px" /></p> <p>Infection with SARS-CoV-2 can affect any organ system in the body, and acute kidney injury (AKI) is common in people with more severe cases of COVID-19. Researchers at Brigham and Women’s Hospital recently led a study that looked at critically ill patients with COVID-19 and identified both patient- and hospital-level risk factors for development of AKI treated with dialysis.</p> <p> <a href="https://www.brighamhealthonamission.org/2020/11/12/uncovering-risks-for-severe-aki-in-covid-19-patients/#more-5159" class="more-link">Read More</a></p> <div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-5159" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2020/11/12/uncovering-risks-for-severe-aki-in-covid-19-patients/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-5159" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2020/11/12/uncovering-risks-for-severe-aki-in-covid-19-patients/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-5159" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2020/11/12/uncovering-risks-for-severe-aki-in-covid-19-patients/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2020/11/12/uncovering-risks-for-severe-aki-in-covid-19-patients/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20Uncovering%20Risks%20for%20Severe%20AKI%20in%20COVID-19%20Patients&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2020%2F11%2F12%2Funcovering-risks-for-severe-aki-in-covid-19-patients%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="eaf9a07d4b" data-email-share-track-url="https://www.brighamhealthonamission.org/2020/11/12/uncovering-risks-for-severe-aki-in-covid-19-patients/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-5153" class="post-5153 post type-post status-publish format-standard hentry category-nephrology"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2020/11/12/examining-impact-of-race-in-staging-chronic-kidney-disease/" rel="bookmark">Examining Impact of Race in Staging Chronic Kidney Disease</a></h1> </header> <div class="entry-summary"> <p><img loading="lazy" decoding="async" class="aligncenter size-medium wp-image-5156" src="https://www.brighamhealthonamission.org/wp-content/uploads/2020/11/neph-eGFR-blog-300x200.jpg" alt="Patient getting dialysis" width="300" height="200" srcset="https://www.brighamhealthonamission.org/wp-content/uploads/2020/11/neph-eGFR-blog-300x200.jpg 300w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/11/neph-eGFR-blog-1024x683.jpg 1024w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/11/neph-eGFR-blog-768x512.jpg 768w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/11/neph-eGFR-blog-1536x1024.jpg 1536w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/11/neph-eGFR-blog-2048x1365.jpg 2048w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/11/neph-eGFR-blog-1200x800.jpg 1200w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/11/neph-eGFR-blog-750x500.jpg 750w" sizes="auto, (max-width: 300px) 100vw, 300px" /></p> <p>An equation used for over a decade to estimate kidney function and stage chronic kidney disease (CKD) can underestimate kidney function and lead to gaps in care delivery in African-American patients, according to research led by investigators at Brigham and Women’s Hospital.</p> <p> <a href="https://www.brighamhealthonamission.org/2020/11/12/examining-impact-of-race-in-staging-chronic-kidney-disease/#more-5153" class="more-link">Read More</a></p> <div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-5153" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2020/11/12/examining-impact-of-race-in-staging-chronic-kidney-disease/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-5153" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2020/11/12/examining-impact-of-race-in-staging-chronic-kidney-disease/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-5153" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2020/11/12/examining-impact-of-race-in-staging-chronic-kidney-disease/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2020/11/12/examining-impact-of-race-in-staging-chronic-kidney-disease/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20Examining%20Impact%20of%20Race%20in%20Staging%20Chronic%20Kidney%20Disease&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2020%2F11%2F12%2Fexamining-impact-of-race-in-staging-chronic-kidney-disease%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="b59669aa7f" data-email-share-track-url="https://www.brighamhealthonamission.org/2020/11/12/examining-impact-of-race-in-staging-chronic-kidney-disease/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-5045" class="post-5045 post type-post status-publish format-standard hentry category-covid-19 category-nephrology"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2020/08/05/first-nationwide-study-of-critically-ill-covid-19-patients/" rel="bookmark">First Nationwide Study of Critically Ill COVID-19 Patients</a></h1> </header> <div class="entry-summary"> <p><img loading="lazy" decoding="async" class="aligncenter wp-image-5049 size-newspack-article-block-landscape-small" src="https://www.brighamhealthonamission.org/wp-content/uploads/2020/08/critically-ill-leaf-400x300.jpg" alt="anesthetist with patient" width="400" height="300" srcset="https://www.brighamhealthonamission.org/wp-content/uploads/2020/08/critically-ill-leaf-400x300.jpg 400w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/08/critically-ill-leaf-1200x900.jpg 1200w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/08/critically-ill-leaf-800x600.jpg 800w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/08/critically-ill-leaf-200x150.jpg 200w" sizes="auto, (max-width: 400px) 100vw, 400px" /></p> <p>Investigators at Brigham and Women鈥檚 Hospital led the first study that offers national data on the factors that may increase the risk of complications or death in critically ill COVID-19 patients. <a href="https://physiciandirectory.brighamandwomens.org/details/12440/david-leaf-renal_kidney_disease-boston" target="_blank" rel="noopener noreferrer">David E. Leaf, MD, MMSc</a> and <a href="https://physiciandirectory.brighamandwomens.org/details/13692/shruti-gupta-medicine-renal_kidney_disease-boston" target="_blank" rel="noopener noreferrer">Shruti Gupta, MD, MPH</a>, physicians in the Brigham鈥檚 <a href="https://www.brighamandwomens.org/medicine/renal/division-of-renal-medicine" target="_blank" rel="noopener noreferrer">Division of Renal Medicine</a>, led a team of more than 300 investigators from over 65 hospitals across the U.S. to examine the demographics, comorbidities, organ dysfunction, treatment and outcomes of patients with COVID-19 admitted to intensive care units (ICUs). <a href="https://www.brighamhealthonamission.org/2020/08/05/first-nationwide-study-of-critically-ill-covid-19-patients/#more-5045" class="more-link">Read More</a></p> <div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-5045" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2020/08/05/first-nationwide-study-of-critically-ill-covid-19-patients/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-5045" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2020/08/05/first-nationwide-study-of-critically-ill-covid-19-patients/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-5045" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2020/08/05/first-nationwide-study-of-critically-ill-covid-19-patients/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2020/08/05/first-nationwide-study-of-critically-ill-covid-19-patients/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20First%20Nationwide%20Study%20of%20Critically%20Ill%20COVID-19%20Patients&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2020%2F08%2F05%2Ffirst-nationwide-study-of-critically-ill-covid-19-patients%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="cbdb7c9437" data-email-share-track-url="https://www.brighamhealthonamission.org/2020/08/05/first-nationwide-study-of-critically-ill-covid-19-patients/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-4980" class="post-4980 post type-post status-publish format-standard hentry category-covid-19 category-nephrology"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2020/05/19/managing-acute-kidney-injury-in-covid-19-patients/" rel="bookmark">Managing Acute Kidney Injury in COVID-19 Patients</a></h1> </header> <div class="entry-summary"> <p> </p> <p><img loading="lazy" decoding="async" class="aligncenter size-medium wp-image-4981" src="https://www.brighamhealthonamission.org/wp-content/uploads/2020/05/aki-300x200.jpg" alt="machine hooked up to wires" width="300" height="200" srcset="https://www.brighamhealthonamission.org/wp-content/uploads/2020/05/aki-300x200.jpg 300w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/05/aki-768x512.jpg 768w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/05/aki-750x500.jpg 750w, https://www.brighamhealthonamission.org/wp-content/uploads/2020/05/aki.jpg 1000w" sizes="auto, (max-width: 300px) 100vw, 300px" />At Brigham and Women鈥檚 Hospital, nephrologists have observed an increased risk of acute kidney injury (AKI) in COVID-19 patients. Within the intensive care units (ICUs) at the Brigham, about 15 to 20 percent of COVID-19 patients have developed AKI. In some hospitals, the incidence of AKI has been reported to be as high as 25 percent.</p> <p> <a href="https://www.brighamhealthonamission.org/2020/05/19/managing-acute-kidney-injury-in-covid-19-patients/#more-4980" class="more-link">Read More</a></p> <div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-4980" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2020/05/19/managing-acute-kidney-injury-in-covid-19-patients/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-4980" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2020/05/19/managing-acute-kidney-injury-in-covid-19-patients/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-4980" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2020/05/19/managing-acute-kidney-injury-in-covid-19-patients/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2020/05/19/managing-acute-kidney-injury-in-covid-19-patients/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20Managing%20Acute%20Kidney%20Injury%20in%20COVID-19%20Patients&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2020%2F05%2F19%2Fmanaging-acute-kidney-injury-in-covid-19-patients%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. 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