Clade I Mpox Outbreak Originating in Central Africa | Mpox

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class="dfe-section__header"> <h2 class="editor-block--title" id="heading-pgpf5g2mgn">What to know</h2> </div> <div class="dfe-section__content">  <div class="desktop-page-summary"> <ul class="nested-list"> <li class="level-1">Since January 1, 2024, the Democratic Republic of the Congo (DRC) has reported more than 47,000 suspected mpox cases and more than 1,000 suspected deaths.<ul> </ul> </li> <li class="level-1">Of these, about 9,000 cases have been confirmed through laboratory testing, with more than 40 confirmed deaths.<ul> </ul> </li> <li class="level-1">There are two types of mpox, clade I and clade II. Clade I has historically caused a higher number of people with mpox to get severely sick or die compared to clade II.<ul> </ul> </li> <li class="level-1">The virus that causes clade I mpox occurs regularly, or is endemic, in DRC.<ul> </ul> </li> <li class="level-1">Clade I mpox has spread to some neighboring countries, including Burundi, Central African Republic, Republic of the Congo, Rwanda, and Uganda.<ul> </ul> </li> <li class="level-1">There have also been travel-associated cases in Germany, India, Kenya, Sweden, Thailand, the United Kingdom, Zambia, and Zimbabwe.<ul> </ul> </li> <li class="level-1">The first case of clade I mpox in the United States has been reported. This case is related to the outbreak in Central and Eastern Africa. The risk of clade I mpox to the general public in the U.S. remains low.<ul> </ul> </li> <li class="level-1">On August 14, 2024, the World Health Organization (WHO) declared the outbreak a Public Health Emergency of International Concern (PHEIC).<ul> </ul> </li> </ul> </div> </div> <div class="dfe-section__image thumbnail_image_shown" id="page-summary-image"> <figure class="dfe-image page_thumbnail dfe-image__large"><div class="image-container calculated-infographic aspect-ratio-16-9"><img src="/mpox/media/images/2024/09/Mpox_Africa_Aug2024.png" alt="Many central and eastern African countries have confirmed cases of clade I mpox." title="2024 Clade I map of affected countries"></div></figure> </div> <div class="d-block d-md-none dfe-section__mobile-summary"> <ul class="nested-list"> <li class="level-1">Since January 1, 2024, the Democratic Republic of the Congo (DRC) has reported more than 47,000 suspected mpox cases and more than 1,000 suspected deaths.<ul> </ul> </li> <li class="level-1">Of these, about 9,000 cases have been confirmed through laboratory testing, with more than 40 confirmed deaths.<ul> </ul> </li> <li class="level-1">There are two types of mpox, clade I and clade II. Clade I has historically caused a higher number of people with mpox to get severely sick or die compared to clade II.<ul> </ul> </li> <li class="level-1">The virus that causes clade I mpox occurs regularly, or is endemic, in DRC.<ul> </ul> </li> <li class="level-1">Clade I mpox has spread to some neighboring countries, including Burundi, Central African Republic, Republic of the Congo, Rwanda, and Uganda.<ul> </ul> </li> <li class="level-1">There have also been travel-associated cases in Germany, India, Kenya, Sweden, Thailand, the United Kingdom, Zambia, and Zimbabwe.<ul> </ul> </li> <li class="level-1">The first case of clade I mpox in the United States has been reported. This case is related to the outbreak in Central and Eastern Africa. The risk of clade I mpox to the general public in the U.S. remains low.<ul> </ul> </li> <li class="level-1">On August 14, 2024, the World Health Organization (WHO) declared the outbreak a Public Health Emergency of International Concern (PHEIC).<ul> </ul> </li> </ul> </div> <div id="nav-buttons" class="dfe-section__desktop-nav-buttons"></div> </div> </div> <div class="cdc-dfe-body__center "> <div class="dfe-section" data-section="cdc_outbreak_main_situation"> <a class="onThisPageAnchor" id="cdc_outbreak_main_situation-situation-summary" name="Situation%20summary" title="Situation summary"></a><h2 class="editor-block--title" id="heading-nelg69b65i">Situation summary</h2> <h3 id="heading-wzejwzlpu2">In the United States</h3> <div class="dfe-block dfe-callout dfe-callout--facts"><div class="cdc-icon-chart-04"></div> <h3>More about mpox cases and outbreaks&lrm;</h3> <div class="dfe-callout__body"><div class="callout-desc">Learn more about mpox in the United States and around the world on the <a href="/mpox/situation-summary/index.html">Mpox Current Situation</a> page. </div> </div></div> <p>The <a href="/media/releases/s1116-california-first-clade.html">first case of clade I mpox in the United States has been reported</a>. This case is related to the outbreak in Central and Eastern Africa. No additional cases have been reported at this time. CDC is working closely with local and state health authorities to rapidly investigate the circumstances surrounding this first case and prevent any spread. <br><br>CDC has <a href="/cfa-qualitative-assessments/php/data-research/mpox-risk-assessment/index.html">assessed the risk to the United States</a> posed by the clade I mpox outbreak in Central and Eastern Africa. The risk to the general population is assessed as low. The <a href="/cfa-qualitative-assessments/php/data-research/mpox-risk-assessment/index.html">current risk to gay, bisexual, and other men who have sex with men</a> (MSM) who have more than one sexual partner, and people who have sex with MSM partners, is assessed as low to moderate. The risk might change as more information becomes available.</p> <p><strong>Mpox needs close or intimate contact to spread, so it's not spread through casual contact</strong>, such as one might have in public spaces like markets, offices, classrooms, or during travel. The best protection against mpox is two doses of the JYNNEOS <a href="/mpox/vaccines/index.html" class="ce-selection">vaccine</a> if you're eligible. People can also protect themselves by:</p> <ul class="nested-list"> <li class="level-1">Avoiding close contact with people who are sick with signs and symptoms of mpox, including those with skin lesions or genital lesions.<ul> </ul> </li> <li class="level-1">Avoiding contact with wild animals (alive or dead) in areas where mpox regularly occurs.<ul> </ul> </li> <li class="level-1">Avoiding contact with contaminated materials used by people who are sick with mpox (such as clothing, bedding, or materials used in healthcare settings) or that came into contact with wild animals.<ul> </ul> </li> <li class="level-1">Avoiding eating or preparing meat from wild animals (bushmeat) or using products (creams, lotions, powders) derived from wild animals.<ul> </ul> </li> </ul> <div class="dfe-block dfe-callout dfe-callout--facts"><div class="cdc-icon-chart-04"></div> <h3>CDC mpox prevention recommendations&lrm;</h3> <div class="dfe-callout__body"><div class="callout-desc"><p>Learn more about <a href="/mpox/causes/index.html">which activities may put you at increased risk of exposure </a>when you <a href="https://emergency.cdc.gov/han/2024/han00516.asp">travel to a country where clade I MPXV is spreading</a>: avoid close contact with people who are sick with <a href="/mpox/signs-symptoms/index.html">signs and symptoms of mpox</a>, including those with skin or genital lesions; and avoid contact with contaminated materials used by people who are sick (such as clothing, bedding, toothbrushes, sex toys, or materials used in healthcare settings).</p><p><br></p><p>CDC has updated vaccination recommendations for people traveling to countries with clade I outbreaks. <a href="/mpox/vaccines/index.html" style="background-color: rgb(255, 255, 255);">Get vaccinated with two doses of JYNNEOS</a> if you anticipate experiencing any of the following: 1) Sex with a new partner 2) Sex at a commercial sex venue, such as a sex club or bathhouse 3) Sex in exchange for money, goods, drugs, or other trade 4) Sex in association with a large public event, such as a rave, party, or festival).</p><p><br><strong>As of September 19, 2024, these countries include: Burundi, Central African Republic, Democratic Republic of the Congo, Republic of the Congo, Rwanda, and Uganda.</strong></p></div> </div></div> <h3 id="heading-wbs1apgtff">In the Democratic Republic of the Congo</h3> <p>There are several outbreaks happening at the same time in DRC, with cases reported throughout the country, in the capital city of Kinshasa, and in some other large cities. In DRC, different provinces have outbreaks with different features. In some provinces, patients have acquired infection through contact with infected dead or live wild animals, household spread, or patient care (transmitted when appropriate PPE wasn't used or available); a high proportion of cases have been reported in children younger than 15 years of age. In other provinces, the cases are associated with sexual contact among men who have sex with men and female sex workers and their contacts. These are the first reported cases of sexual transmission with clade I mpox.</p> <p>CDC has been supporting DRC mpox research and response for more than 20 years. CDC and other U.S. government agencies are on the ground in DRC helping partners in the country with disease surveillance, laboratory capacity including testing materials, strengthening workforce capacity, case investigation, case management, infection prevention and control, border health, and risk communication and community engagement. DRC has approved the use of vaccines in-country, so CDC is working with other U.S. government agencies and partners on a strategy for vaccination in DRC.</p> <h3 id="heading-dkxg04ifro">In Central and Eastern Africa</h3> <div class="dfe-block dfe-callout dfe-callout--standard"><div class="dfe-callout__icon" aria-hidden="true" role="img"></div> <h3>Public Health Emergency of International Concern Declaration&lrm;</h3> <div class="dfe-callout__body"><div class="callout-desc">On August 14, 2024, the World Health Organization (WHO) declared the outbreak a <a href="https://www.who.int/news/item/14-08-2024-who-director-general-declares-mpox-outbreak-a-public-health-emergency-of-international-concern" class="tp-link-policy" rel="noreferrer" data-domain-ext="int">Public Health Emergency of International Concern (PHEIC)<span class="visually-hidden sr-only" aria-label=" external icon" role="img"></span><span class="cdc-icon-external cdc-link-icon" aria-hidden="true" alt="external icon"></span></a>. This is the WHO's highest level of global alert, and the decision recognizes the potential threat this virus poses to countries around the world. The declaration focuses international attention on acute public health risks that require coordinated mobilization of extraordinary resources by the international community for prevention and response. Read more about the <a href="/media/releases/2024/s0822-mpox-outbreak.html" class="">United States Government's response</a> to the outbreaks in several African countries.</div> </div></div> <figure class="dfe-image dfe-image__large"><div class="links-options"><span class="file-view d-none d-sm-inline image-modal"><a href="#">View Larger</a></span></div><div class="image-container calculated-infographic aspect-ratio-16-9"><img src="/mpox/media/images/2024/09/Mpox_Africa_Aug2024.png" alt="Map of Central and Eastern Africa showing countries with endemic and non-endemic mpox" title="2024 Clade I map"></div> <div class="dfe-image-caption-container"><figcaption class="dfe-image-caption" id="caption-866-673d00275b9ac">Mpox cases are occurring in several countries in Central and Eastern Africa</figcaption></div></figure> <p>The Republic of the Congo (ROC), which borders DRC to the west, declared a clade I mpox outbreak in April 2024. There have also been confirmed clade I cases in Central African Republic (CAR), which borders DRC to the north. Clade I mpox occurs regularly in ROC and CAR, but the new cases appear to be linked to spread from DRC. In late July 2024, the disease spread to countries that are not known to be endemic for the virus that causes mpox: Burundi, Rwanda, and Uganda, which sit on the eastern border of DRC, and Kenya, which has reported cases of travel-associated mpox only. Although contact tracing is ongoing, some cases have links to DRC. Person-to-person transmission has occurred during this outbreak, including through sexual contact, household contact, and within healthcare settings, when personal protective equipment was not available.</p> <p>CDC is working with Ministries of Health and in-country partners across the region on disease surveillance, laboratory capacity including testing materials, strengthening workforce capacity, case investigation, case management, infection prevention and control, border health, and risk communication and community engagement.</p> <figure class="dfe-image dfe-image__small"><div class="links-options"><span class="file-view d-none d-sm-inline image-modal"><a href="#">View Larger</a></span></div><div class="image-container calculated-ratio-4-3 aspect-ratio-16-9"><img src="/mpox/media/images/2024/10/Rebekah-Tiller_Jennifer-Kasten_donated-reagents.jpeg" alt="two women stand by a table covered in boxes, which contain laboratory testing supplies for mpox" title="CDC donated reagents in Burundi"></div> <div class="dfe-image-caption-container"><figcaption class="dfe-image-caption" id="caption-1055-673d00275c467">CDC staff in Burundi with donated laboratory supplies to be used for mpox testing</figcaption></div></figure> <h3 id="heading-lykep8lkjv">Global situation</h3> <ul class="nested-list"> <li class="level-1">A case of clade I mpox in a Swedish traveler who visited an affected country in Africa was announced August 15. This was the first clade I mpox case to be reported outside of the African continent.<ul> </ul> </li> <li class="level-1">Thailand announced August 22 that a traveler to that country from DRC was diagnosed with clade I mpox.<ul> </ul> </li> <li class="level-1">India announced a clade I mpox case September 25.<ul> </ul> </li> <li class="level-1">Germany announced a clade I mpox case in October 2024 in someone who'd traveled to an affected country in east Africa.<ul> </ul> </li> <li class="level-1">The United Kingdom announced 4 cases from the same household in October - November 2024.<ul> </ul> </li> <li class="level-1">Zambia announced a travel-associated case in October 2024.<ul> </ul> </li> <li class="level-1">Zimbabwe announced a travel-associated case in November 2024.<ul> </ul> </li> <li class="level-1">The United States announced a travel-associated case in November 2024.<ul> </ul> </li> </ul> <p>A single person with mpox is not cause for widespread concern, since public health authorities can quickly identify, isolate, and treat the person or family, and the risk of spread to other people and households can be minimized. Rapid response measures, such as contact tracing and vaccination, can effectively contain disease in these situations.</p> <div class="dfe-block dfe-block--cdcmodule cdc_visualization dfe-block--width-wide"><div class="dfe-block__inner"><div class="mb-3"><div data-language="en" data-host="www.cdc.gov" class="wcms-viz-container" data-config-url="/mpox/outbreaks/modules/mpox-global-situation-cladeI-map-URL.json" data-sid=""></div></div></div></div><p><strong>Notes: </strong>Case data reported in humans to WHO since January 1, 2024, are provided for situational awareness and subject to change. Confirmed cases include those laboratory-confirmed as monkeypox virus and may include cases only confirmed as orthopoxvirus. For more information and additional limitations, see WHO-reported data at <a href="https://worldhealthorg.shinyapps.io/mpx_global/#8_Disclaimers" class="tp-link-policy" rel="noreferrer" data-domain-ext="io">2022-24 Mpox (Monkeypox) Outbreak: Global Trends (shinyapps.io)<span class="visually-hidden sr-only" aria-label=" external icon" role="img"></span><span class="cdc-icon-external cdc-link-icon" aria-hidden="true" alt="external icon"></span></a>.</p> <p><strong>Source:</strong> 2022-24 Mpox Outbreak: Global Trends. Geneva: World Health Organization, 2024. Available online: <a href="https://worldhealthorg.shinyapps.io/mpx_global/" class="tp-link-policy" rel="noreferrer" data-domain-ext="io">https://worldhealthorg.shinyapps.io/mpx_global/<span class="visually-hidden sr-only" aria-label=" external icon" role="img"></span><span class="cdc-icon-external cdc-link-icon" aria-hidden="true" alt="external icon"></span></a> (last cited: August 27, 2024)</p> </div> <div class="dfe-section" data-section="cdc_outbreak_main_see-also"> <a class="onThisPageAnchor" id="cdc_outbreak_main_see-also-resources" name="Resources" title="Resources"></a><h2 class="editor-block--title" id="heading-yo2g5bzv3t">Resources</h2> <h3 id="heading-zenad9mgsz">For the public</h3> <div class="dfe-links-layout--list"><div class="dfe-curated-link dfe-curated-link--list" data-post><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="https://wwwnc.cdc.gov/travel/notices/level2/mpox-drc-neighboring-countries">Updated Travel Health Notice to Democratic Republic of the Congo, August 2024</a></div> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="1486_43"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/about/index.html">About Mpox</a></div> <div class="dfe-curated-link__desc">Learn about mpox, how it spreads, and ways to protect yourself</div> <time class="dfe-curated-link__date">Oct. 13, 2023</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="1486_62"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/signs-symptoms/index.html">Signs and Symptoms of Mpox</a></div> <div class="dfe-curated-link__desc">Learn the signs and symptoms of mpox, such as a new or unexplained rash</div> <time class="dfe-curated-link__date">Sept. 12, 2024</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="1486_63"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/causes/index.html">How Mpox Spreads</a></div> <div class="dfe-curated-link__desc">Mpox mainly spreads through close contact with an infected person</div> <time class="dfe-curated-link__date">Aug. 5, 2024</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="1486_67"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/prevention/index.html">Preventing Mpox</a></div> <div class="dfe-curated-link__desc">Learn the best ways to prevent mpox infection</div> <time class="dfe-curated-link__date">Oct. 16, 2024</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="1486_72"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/vaccines/index.html">Mpox Vaccination</a></div> <div class="dfe-curated-link__desc">Learn who should be vaccinated against mpox, how the vaccine is given, and where to find it</div> <time class="dfe-curated-link__date">Nov. 16, 2024</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="1486_77"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/caring/index.html">What to Do If You Are Sick</a></div> <div class="dfe-curated-link__desc">Learn how to take care of yourself if you have mpox and prevent spread to others</div> <time class="dfe-curated-link__date">Aug. 26, 2024</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="1486_861"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/outbreaks/2022/index-1.html">Ongoing Clade II Mpox Global Outbreak</a></div> <div class="dfe-curated-link__desc">Information on the ongoing outbreak of Clade II mpox</div> <time class="dfe-curated-link__date">Nov. 8, 2024</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div></div><h3 id="heading-silii2xirv">For clinicians, public health partners, and laboratory staff</h3> <div class="dfe-links-layout--list"><div class="dfe-curated-link dfe-curated-link--list" data-post="1486_94"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/hcp/clinical-overview/index.html">Clinical Overview of Mpox</a></div> <div class="dfe-curated-link__desc">Evaluating, testing, and managing patients with mpox</div> <time class="dfe-curated-link__date">Sept. 12, 2024</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="1486_95"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/hcp/clinical-signs/index.html">Clinical Features of Mpox</a></div> <div class="dfe-curated-link__desc">Learn the key characteristics of mpox and disease stages</div> <time class="dfe-curated-link__date">Sept. 12, 2024</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="1486_93"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/hcp/case-definitions/index.html">Mpox Case Definitions</a></div> <div class="dfe-curated-link__desc">Case definitions for mpox cases and reinfections</div> <time class="dfe-curated-link__date">Sept. 12, 2024</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="1486_96"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/hcp/diagnosis-testing/index.html">Diagnostic Testing for Mpox</a></div> <div class="dfe-curated-link__desc">Information for clinicians on available diagnostic tests for mpox and how to test</div> <time class="dfe-curated-link__date">Aug. 27, 2024</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="1486_119"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/php/case-reporting/index.html">Mpox Case Reporting Recommendations</a></div> <div class="dfe-curated-link__desc">Mpox case reporting information for health departments</div> <time class="dfe-curated-link__date">Sept. 12, 2024</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="1486_97"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/hcp/clinical-care/index.html">Clinical Treatment of Mpox</a></div> <div class="dfe-curated-link__desc">Clinical guidance for available mpox biologics and treatment options</div> <time class="dfe-curated-link__date">Sept. 13, 2024</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="1486_359"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/hcp/infection-control/index.html">Mpox Infection Control</a></div> <div class="dfe-curated-link__desc">Mpox infection control in healthcare settings, households, and when handling human remains.</div> <time class="dfe-curated-link__date">Sept. 13, 2024</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="1486_122"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/hcp/laboratories/index.html">Mpox Laboratory Information</a></div> <div class="dfe-curated-link__desc">Information for laboratory personnel on testing and procedures for mpox</div> <time class="dfe-curated-link__date">Sept. 13, 2024</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="1486_103"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/hcp/veterinary/index.html">Veterinary Guidance for Mpox</a></div> <div class="dfe-curated-link__desc">Guidance for veterinarians and animal health officials on handling animals with mpox</div> <time class="dfe-curated-link__date">Sept. 12, 2024</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="1486_908"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="/mpox/php/data-research/science-updates/index.html">Mpox Science Agenda, Reports, and Additional Materials</a></div> <div class="dfe-curated-link__desc">Information about data and research for mpox</div> <time class="dfe-curated-link__date">Nov. 16, 2024</time> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div></div><h4 id="heading-bpne8cmsz_">Health alert network</h4> <div class="dfe-links-layout--list"><div class="dfe-curated-link dfe-curated-link--list" data-post><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="https://emergency.cdc.gov/han/2024/han00519.asp">Health Alert Network (HAN) 00519 | First Case of Clade I Mpox Diagnosed in the United States</a></div> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="https://emergency.cdc.gov/han/2024/han00516.asp">Health Alert Network (HAN) - 00516 | Prevention Strategies for Mpox, including Vaccinating People at Risk via Sexual Exposure, for U.S. Travelers Visiting Countries with Clade I Mpox Outbreaks</a></div> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="https://emergency.cdc.gov/han/2024/han00513.asp">Health Alert Network (HAN) – 00513 | Mpox Caused by Human-to-Human Transmission of Monkeypox Virus in the Democratic Republic of the Congo with Spread to Neighboring Countries (cdc.gov)</a></div> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="https://emergency.cdc.gov/han/2023/han00501.asp">Health Alert Network (HAN) – 00501 | Mpox Caused by Human-to-Human Transmission of Monkeypox Virus with Geographic Spread in the Democratic Republic of the Congo</a></div> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div></div><h4 id="heading-e_h8bser7q">Publications</h4> <div class="dfe-links-layout--list"><div class="dfe-curated-link dfe-curated-link--list" data-post="826_104513"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a aria-label="View" target="_blank" class="cdc-block-link" href="https://www.cdc.gov/mmwr/volumes/72/wr/pdfs/mm7220a2-H.pdf">The CDC Domestic Mpox Response — United States, 2022–2023<span aria-label=" pdf icon" role="img" class="sr-only"></span><span class="cdc-link-icon cdc-link-icon--pdf" aria-hidden="true"></span></a></div> <div class="dfe-curated-link__desc">The CDC Domestic Mpox Response — United States, 2022–2023</div> <time class="dfe-curated-link__date">May 17, 2023</time> <div class="featured download"><div class="download-container"><a class="cdc-block-link" href="https://www.cdc.gov/mmwr/volumes/72/wr/pdfs/mm7220a2-H.pdf" aria-label="Download" download="mm7220a2-H.pdf" target="_blank"><span class="cdc-fa-arrow-down-to-line"> </span><span class="down_label">Download</span><span aria-label=" pdf icon" role="img" class="sr-only"></span><span class="cdc-link-icon cdc-link-icon--pdf" aria-hidden="true"></span></a></div></div></div> <div class="dfe-curated-link__download"><div class="download-container"><a class="cdc-block-link" href="https://www.cdc.gov/mmwr/volumes/72/wr/pdfs/mm7220a2-H.pdf" aria-label="Download" download="mm7220a2-H.pdf" target="_blank"><span class="cdc-fa-arrow-down-to-line"> </span><span class="down_label">Download</span><span aria-label=" pdf icon" role="img" class="sr-only"></span><span class="cdc-link-icon cdc-link-icon--pdf" aria-hidden="true"></span></a></div></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="826_111711"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="https://www.cdc.gov/mmwr/volumes/73/wr/mm7319a3.htm">U.S. Preparedness and Response to Increasing Clade I Mpox Cases in the Democratic Republic of the Congo — United States, 2024</a></div> <div class="dfe-curated-link__desc">MMWR. Morbidity and Mortality Weekly Report / Vol. 73 / No. 19 / P. 435–440</div> <time class="dfe-curated-link__date">May 15, 2024</time> <span class="dfe-curated-link__alt-formats"></span> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="826_111975"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="https://www.cdc.gov/mmwr/volumes/73/wr/mm7320a3.htm">Monkeypox Virus Infections After 2 Preexposure Doses of JYNNEOS Vaccine — United States, May 2022–May 2024</a></div> <div class="dfe-curated-link__desc">MMWR. Morbidity and Mortality Weekly Report / Vol. 73 / No. 20 / P. 460–466</div> <time class="dfe-curated-link__date">May 22, 2024</time> <span class="dfe-curated-link__alt-formats"></span> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div> <div class="dfe-curated-link dfe-curated-link--list" data-post="826_111964"><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link" href="https://www.cdc.gov/mmwr/volumes/73/wr/mm7320a4.htm?s_cid=mm7320a4_w">Notes from the Field: Clade II Mpox Surveillance Update — United States, October 2023–April 2024</a></div> <div class="dfe-curated-link__desc">MMWR. Morbidity and Mortality Weekly Report / Vol. 73 / No. 20 / P. 474–476</div> <time class="dfe-curated-link__date">May 22, 2024</time> <span class="dfe-curated-link__alt-formats"></span> <div class="featured download"></div></div> <div class="dfe-curated-link__download"></div></div></div><h4 id="heading-ye_cuqd2vp">Toolkits</h4> <div class="dfe-links-layout--list"><div class="dfe-curated-link dfe-curated-link--list" data-post><div class="dfe-curated-link__content list"><div class="dfe-curated-link__title"><a class="cdc-block-link tp-link-policy" href="https://www.ncsddc.org/resource/mpox-communications-toolkit/" rel="noreferrer" data-domain-ext="org">National Coalition of STD Directors: Mpox Communications Toolkit and Creative Assets <span class="visually-hidden sr-only" aria-label=" external icon" role="img"></span><span class="cdc-icon-external cdc-link-icon" aria-hidden="true" alt="external icon"></span></a></div> <div class="featured download"></div></div> <div 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href="/mpox/index.html"> Mpox </a> <i class="cdc-icon cdc-fa-light cdc-fa-angle-right"></i> </span> </a> </h2> <p>Mpox is a viral disease that can be spread between people or between people and certain animals.</p> <a href="/mpox/site.html" class="btn-outline__half btn btn-outline-white btn-arrow"> View All </a> </div> <div class="col-lg-8 offset-lg-1"> <div class="row site-footer__links"> <div class="col-md-6">  <h3 class="site-footer__links__header"> <a class="cdc-footer__super-link" href="/mpox/index.html#gen"> <span>For Everyone</span> <span class="cdc-icon cdc-fa-light cdc-fa-angle-right"></span> </a> </h3> <ul> <li> <a data-post-id="547" href="/mpox/situation-summary/index.html"> Current Situation </a> </li> <li> <a data-post-id="128" href="/mpox/data-research/cases/index.html"> U.S. Case Data </a> </li> <li> <a data-post-id="43" href="/mpox/about/index.html"> About </a> </li> <li> <a data-post-id="62" href="/mpox/signs-symptoms/index.html"> Signs and Symptoms </a> </li> <li> <a 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