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Search results for: Sumedha Ojha
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class="col-md-9 mx-auto"> <form method="get" action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Sumedha Ojha"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 7</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Sumedha Ojha</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> Multi-Criteria Based Robust Markowitz Model under Box Uncertainty</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Pulak%20Swain">Pulak Swain</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20K.%20Ojha"> A. K. Ojha</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Portfolio optimization is based on dealing with the problems of efficient asset allocation. Risk and Expected return are two conflicting criteria in such problems, where the investor prefers the return to be high and the risk to be low. Using multi-objective approach we can solve those type of problems. However the information which we have for the input parameters are generally ambiguous and the input values can fluctuate around some nominal values. We can not ignore the uncertainty in input values, as they can affect the asset allocation drastically. So we use Robust Optimization approach to the problems where the input parameters comes under box uncertainty. In this paper, we solve the multi criteria robust problem with the help of E- constraint method. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=portfolio%20optimization" title="portfolio optimization">portfolio optimization</a>, <a href="https://publications.waset.org/abstracts/search?q=multi-objective%20optimization" title=" multi-objective optimization"> multi-objective optimization</a>, <a href="https://publications.waset.org/abstracts/search?q=%CF%B5%20-%20constraint%20method" title=" ϵ - constraint method"> ϵ - constraint method</a>, <a href="https://publications.waset.org/abstracts/search?q=box%20uncertainty" title=" box uncertainty"> box uncertainty</a>, <a href="https://publications.waset.org/abstracts/search?q=robust%20optimization" title=" robust optimization"> robust optimization</a> </p> <a href="https://publications.waset.org/abstracts/118411/multi-criteria-based-robust-markowitz-model-under-box-uncertainty" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/118411.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">139</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> In vitro Estimation of Genotoxic Lesions in Peripheral Blood Lymphocytes of Rat Exposed to Organophosphate Pesticides</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20Ojha">A. Ojha</a>, <a href="https://publications.waset.org/abstracts/search?q=Y.%20K.%20Gupta"> Y. K. Gupta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Organophosphate (OP) pesticides are among the most widely used synthetic chemicals for controlling a wide variety of pests throughout the world. Chlorpyrifos (CPF), methyl parathion (MPT), and malathion (MLT) are among the most extensively used OP pesticides in India. DNA strand breaks and DNA-protein crosslinks (DPC) are toxic lesions associated with the mechanisms of toxicity of genotoxic compounds. In the present study, we have examined the potential of CPF, MPT, and MLT individually and in combination, to cause DNA strand breakage and DPC formation. Peripheral blood lymphocytes of rat were exposed to 1/4 and 1/10 LC50 dose of CPF, MPT, and MLT for 2, 4, 8, and 12h. The DNA strand break was measured by the comet assay and expressed as DNA damage index while DPC estimation was done by fluorescence emission. There was significantly marked increase in DNA damage and DNA-protein crosslink formation in time and dose dependent manner. It was also observed that MPT caused the highest level of DNA damage as compared to other studied OP compounds. Thus, from present study, we can conclude that studied pesticides have genotoxic potential. The pesticides mixture does not potentiate the toxicity of each other. Nonetheless, additional in vivo data are required before a definitive conclusion can be drawn regarding hazard prediction to humans. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=organophosphate" title="organophosphate">organophosphate</a>, <a href="https://publications.waset.org/abstracts/search?q=pesticides" title=" pesticides"> pesticides</a>, <a href="https://publications.waset.org/abstracts/search?q=DNA%20damage" title=" DNA damage"> DNA damage</a>, <a href="https://publications.waset.org/abstracts/search?q=DNA%20protein%20crosslink" title=" DNA protein crosslink"> DNA protein crosslink</a>, <a href="https://publications.waset.org/abstracts/search?q=genotoxic" title=" genotoxic"> genotoxic</a> </p> <a href="https://publications.waset.org/abstracts/14835/in-vitro-estimation-of-genotoxic-lesions-in-peripheral-blood-lymphocytes-of-rat-exposed-to-organophosphate-pesticides" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/14835.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">356</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Reduction of Aerodynamic Drag Using Vortex Generators</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Siddharth%20Ojha">Siddharth Ojha</a>, <a href="https://publications.waset.org/abstracts/search?q=Varun%20Dua"> Varun Dua</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Classified as one of the most important reasons of aerodynamic drag in the sedan automobiles is the fluid flow separation near the vehicle’s rear end. To retard the separation of flow, bump-shaped vortex generators are being tested for its implementation to the roof end of a sedan vehicle. Frequently used in the aircrafts to prevent the separation of fluid flow, vortex generators themselves produce drag, but they also substantially reduce drag by preventing flow separation at the downstream. The net effects of vortex generators can be calculated by summing the positive and negative impacts and effects. Since this effect depends on dimensions and geometry of vortex generators, those present on the vehicle roof are optimized for maximum efficiency and performance. The model was tested through ANSYS CFD analysis and modeling. The model was tested in the wind tunnel for observing it’s properties such as aerodynamic drag and flow separation and a major time lag was gained by employing vortex generators in the scaled model. Major conclusions which were recorded during the analysis were a substantial 24% reduction in the aerodynamic drag and 14% increase in the efficiency of the sedan automobile as the flow separation from the surface is delayed. This paper presents the results of optimization, the effect of vortex generators in the flow field and the mechanism by which these effects occur and are regulated. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aerodynamics" title="aerodynamics">aerodynamics</a>, <a href="https://publications.waset.org/abstracts/search?q=aerodynamic%20devices" title=" aerodynamic devices"> aerodynamic devices</a>, <a href="https://publications.waset.org/abstracts/search?q=body" title=" body"> body</a>, <a href="https://publications.waset.org/abstracts/search?q=computational%20fluid%20dynamics%20%28CFD%29" title=" computational fluid dynamics (CFD)"> computational fluid dynamics (CFD)</a>, <a href="https://publications.waset.org/abstracts/search?q=flow%20visualization" title=" flow visualization"> flow visualization</a> </p> <a href="https://publications.waset.org/abstracts/76172/reduction-of-aerodynamic-drag-using-vortex-generators" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/76172.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">223</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Assessing Significance of Correlation with Binomial Distribution</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Vijay%20Kumar%20Singh">Vijay Kumar Singh</a>, <a href="https://publications.waset.org/abstracts/search?q=Pooja%20Kushwaha"> Pooja Kushwaha</a>, <a href="https://publications.waset.org/abstracts/search?q=Prabhat%20Ranjan"> Prabhat Ranjan</a>, <a href="https://publications.waset.org/abstracts/search?q=Krishna%20Kumar%20Ojha"> Krishna Kumar Ojha</a>, <a href="https://publications.waset.org/abstracts/search?q=Jitendra%20Kumar"> Jitendra Kumar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Present day high-throughput genomic technologies, NGS/microarrays, are producing large volume of data that require improved analysis methods to make sense of the data. The correlation between genes and samples has been regularly used to gain insight into many biological phenomena including, but not limited to, co-expression/co-regulation, gene regulatory networks, clustering and pattern identification. However, presence of outliers and violation of assumptions underlying Pearson correlation is frequent and may distort the actual correlation between the genes and lead to spurious conclusions. Here, we report a method to measure the strength of association between genes. The method assumes that the expression values of a gene are Bernoulli random variables whose outcome depends on the sample being probed. The method considers the two genes as uncorrelated if the number of sample with same outcome for both the genes (Ns) is equal to certainly expected number (Es). The extent of correlation depends on how far Ns can deviate from the Es. The method does not assume normality for the parent population, fairly unaffected by the presence of outliers, can be applied to qualitative data and it uses the binomial distribution to assess the significance of association. At this stage, we would not claim about the superiority of the method over other existing correlation methods, but our method could be another way of calculating correlation in addition to existing methods. The method uses binomial distribution, which has not been used until yet, to assess the significance of association between two variables. We are evaluating the performance of our method on NGS/microarray data, which is noisy and pierce by the outliers, to see if our method can differentiate between spurious and actual correlation. While working with the method, it has not escaped our notice that the method could also be generalized to measure the association of more than two variables which has been proven difficult with the existing methods. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=binomial%20distribution" title="binomial distribution">binomial distribution</a>, <a href="https://publications.waset.org/abstracts/search?q=correlation" title=" correlation"> correlation</a>, <a href="https://publications.waset.org/abstracts/search?q=microarray" title=" microarray"> microarray</a>, <a href="https://publications.waset.org/abstracts/search?q=outliers" title=" outliers"> outliers</a>, <a href="https://publications.waset.org/abstracts/search?q=transcriptome" title=" transcriptome"> transcriptome</a> </p> <a href="https://publications.waset.org/abstracts/60503/assessing-significance-of-correlation-with-binomial-distribution" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/60503.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">415</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Radiation Skin Decontamination Formulation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Navneet%20Sharma">Navneet Sharma</a>, <a href="https://publications.waset.org/abstracts/search?q=Himanshu%20Ojha"> Himanshu Ojha</a>, <a href="https://publications.waset.org/abstracts/search?q=Dharam%20Pal%20Pathak"> Dharam Pal Pathak</a>, <a href="https://publications.waset.org/abstracts/search?q=Rakesh%20Kumar%20Sharma"> Rakesh Kumar Sharma</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Radio-nuclides decontamination is an important task because any extra second of deposition leads to deleterious health effects. We had developed and characterise nanoemulsion of p-tertbutylcalix[4]arens using phase inversion temperature (PIT) method and evaluate its decontamination efficacy (DE). The solubility of the drug was determined in various oils and surfactants. Nanoemulsion developed with an HLB value of 11 and different ratios of the surfactants 10% (7:3, w/w), oil (20%, w/w), and double distilled water (70%) were selected. Formulation was characterised by multi-photon spectroscopy and parameters like viscosity, droplet size distribution, zeta potential and stability were optimised. In vitro and Ex vivo decontamination efficacy (DE) was evaluated against Technetium-99m, Iodine-131, and Thallium-201 as radio-contaminants applied over skin of Sprague-Dawley rat and human tissue equivalent model. Contaminants were removed using formulation soaked in cotton swabs at different time intervals and whole body imaging and static counts were recorded using SPECT gamma camera before and after decontamination attempt. Data were analysed using one-way analysis of variance (ANOVA) and was found to be significant (p <0.05). DE of the nanoemulsion loaded with p-tertbutylcalix[4]arens was compared with placebo and recorded to be 88±5%, 90±3% and 89±3% for 99mTc, 131I and 201Tl respectively. Ex-vivo complexation study of p-tertbutylcalix[4]arene nanoemulsion with surrogate nuclides of radioactive thallium and Iodine, were performed on rat skin mounted on Franz diffusion cell using high-resolution sector field inductively coupled plasma mass spectroscopy (HR-SF-ICPMS). More than 90% complexation of the formulation with these nuclides was observed. Results demonstrate that the prepared nanoemulsion formulation was found efficacious for the decontamination of radionuclides from a large contaminated population. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=p-tertbutylcalix%5B4%5Darens" title="p-tertbutylcalix[4]arens">p-tertbutylcalix[4]arens</a>, <a href="https://publications.waset.org/abstracts/search?q=skin%20decontamination" title=" skin decontamination"> skin decontamination</a>, <a href="https://publications.waset.org/abstracts/search?q=radiological%20emergencies" title=" radiological emergencies"> radiological emergencies</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoemulsion" title=" nanoemulsion"> nanoemulsion</a>, <a href="https://publications.waset.org/abstracts/search?q=iodine-131" title=" iodine-131"> iodine-131</a>, <a href="https://publications.waset.org/abstracts/search?q=thallium-201" title=" thallium-201"> thallium-201</a> </p> <a href="https://publications.waset.org/abstracts/43922/radiation-skin-decontamination-formulation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/43922.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">399</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Bamboo as the Frontier for Economically Sustainable Solution to Flood Control and Human Wildlife Conflict</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nirman%20Kumar%20Ojha">Nirman Kumar Ojha</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bamboo plantation can be integrated for natural embankment against flood and live fencing against wild animals, at the same time provide economic opportunity for the poor farmers as a sustainable solution and adaptation alternative. 2010 flood in the Rui River completely inundated fields of four VDCs in Madi, Chitwan National Park with extensive bank erosion. The main aim of this action research was to identify an economically sustainable natural embankment against flood and also providing wildlife friendly fencing to reduce human-wildlife conflict. Community people especially poor farmers were trained for soil testing, land identification, plantation, and the harvesting regime, nursery set up and intercropping along with bamboo plantation on the edge of the river bank in order to reduce or minimize soil erosion. Results show that farmers are able to establish cost efficient and economically sustainable river embankment with bamboo plantation also creating a fence for wildlife which has also promoted bamboo cultivation and conservation. This action research has amalgamated flood control and wildlife control with the livelihood of the farmers which otherwise would cost huge resource. Another major impact of the bamboo plantation is its role in climate change and its adaptation process reducing degradation and improving vegetation cover contributing to landscape management. Based on this study, we conclude that bamboo plantation in Madi, Chitwan promoted the livelihood of the poor farmers providing a sustainable economic solution to reduce bank erosion, human-wildlife conflict and contributes to landscape management. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=climate%20change%20and%20conservation" title="climate change and conservation">climate change and conservation</a>, <a href="https://publications.waset.org/abstracts/search?q=economic%20opportunity" title=" economic opportunity"> economic opportunity</a>, <a href="https://publications.waset.org/abstracts/search?q=flood%20control" title=" flood control"> flood control</a>, <a href="https://publications.waset.org/abstracts/search?q=national%20park" title=" national park"> national park</a> </p> <a href="https://publications.waset.org/abstracts/55697/bamboo-as-the-frontier-for-economically-sustainable-solution-to-flood-control-and-human-wildlife-conflict" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/55697.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">278</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Application of 2D Electrical Resistivity Tomographic Imaging Technique to Study Climate Induced Landslide and Slope Stability through the Analysis of Factor of Safety: A Case Study in Ooty Area, Tamil Nadu, India</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20Maniruzzaman">S. Maniruzzaman</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Ramanujam"> N. Ramanujam</a>, <a href="https://publications.waset.org/abstracts/search?q=Qazi%20Akhter%20Rasool"> Qazi Akhter Rasool</a>, <a href="https://publications.waset.org/abstracts/search?q=Swapan%20Kumar%20Biswas"> Swapan Kumar Biswas</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Prasad"> P. Prasad</a>, <a href="https://publications.waset.org/abstracts/search?q=Chandrakanta%20Ojha"> Chandrakanta Ojha</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Landslide is one of the major natural disasters in South Asian countries. Applying 2D Electrical Resistivity Tomographic Imaging estimation of geometry, thickness, and depth of failure zone of the landslide can be made. Landslide is a pertinent problem in Nilgris plateau next to Himalaya. Nilgris range consists of hard Archean metamorphic rocks. Intense weathering prevailed during the Pre-Cambrian time had deformed the rocks up to 45m depth. The landslides are dominant in the southern and eastern part of plateau of is comparatively smaller than the northern drainage basins, as it has low density of drainage; coarse texture permitted the more of infiltration of rainwater, whereas in the northern part of the plateau entombed with high density of drainage pattern and fine texture with less infiltration than run off, and low to the susceptible to landslide. To get comprehensive information about the landslide zone 2D Electrical Resistivity Tomographic imaging study with CRM 500 Resistivity meter are used in Coonoor– Mettupalyam sector of Nilgiris plateau. To calculate Factor of Safety the infinite slope model of Brunsden and Prior is used. Factor of Safety can be expressed (FS) as the ratio of resisting forces to disturbing forces. If FS < 1 disturbing forces are larger than resisting forces and failure may occur. The geotechnical parameters of soil samples are calculated on the basis upon the apparent resistivity values for litho units of measured from 2D ERT image of the landslide zone. Relationship between friction angles for various soil properties is established by simple regression analysis from apparent resistivity data. Increase of water content in slide zone reduces the effectiveness of the shearing resistance and increase the sliding movement. Time-lapse resistivity changes to slope failure is determined through geophysical Factor of Safety which depends on resistivity and site topography. This ERT technique infers soil property at variable depths in wider areas. This approach to retrieve the soil property and overcomes the limit of the point of information provided by rain gauges and porous probes. Monitoring of slope stability without altering soil structure through the ERT technique is non-invasive with low cost. In landslide prone area an automated Electrical Resistivity Tomographic Imaging system should be installed permanently with electrode networks to monitor the hydraulic precursors to monitor landslide movement. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=2D%20ERT" title="2D ERT">2D ERT</a>, <a href="https://publications.waset.org/abstracts/search?q=landslide" title=" landslide"> landslide</a>, <a href="https://publications.waset.org/abstracts/search?q=safety%20factor" title=" safety factor"> safety factor</a>, <a href="https://publications.waset.org/abstracts/search?q=slope%20stability" title=" slope stability"> slope stability</a> </p> <a href="https://publications.waset.org/abstracts/68611/application-of-2d-electrical-resistivity-tomographic-imaging-technique-to-study-climate-induced-landslide-and-slope-stability-through-the-analysis-of-factor-of-safety-a-case-study-in-ooty-area-tamil-nadu-india" class="btn btn-primary 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