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Containment solutions for pharmaceutical dust | Camfil

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The API’s create very fine dusts and often high solvent concentrations during the product handling and manufacturing processes. This fine dusts pose the greatest risk to the worker’s health, with harmful particles being retained in the lungs. That&#180;s why effective filtration is required combined with containment solutions to ensure the dust doesn’t escape during normal operation as well as during routine maintenance like filter changes or waste dust disposal.&#160; </p> </div> </div> <div class="col-12 col-md-3"> </div> <div class="col-12 "> <h2 class="u-heading"> Dust extraction &amp; containment </h2> </div> <!-- TextAndImageInTwoColumns start --> <div class="TextAndImageInTwoColumns col-12 mb-4"> <div class="row"> <div class="col-12 col-md-6 order-2"> <div class="TextAndImageInTwoColumns-text"> <div> In general containment in a dedusting process means, to ensure that no harmful emissions, potent compounds and combustible dust gets out of the process, become airborne and enters the ambient air.<br />There are two key concerns which are critical when handling pharmaceutical dusts: the potent, toxic or allergenic properties of the compound as it relates to personnel exposure and the explosion properties of the compound.<br />The first issue involves understanding the toxicological properties of the handled materials, reviewing the occupational exposure limit (OEL) and performing a risk-based exposure evaluation to determine the methods for proper control. Secondly, the fugitive dust particles, which are often invisible to the eye, can create fire and explosion hazards when depositing on the machinery and other surfaces in the production. </div> </div> </div> <div class="TextAndImageInTwoColumns-image col-12 col-md-6 order-1"> <!-- LinkedImage start --> <!-- LinkedImage start Image --> <img src="/-/media/images/qbank/__web/insight/life-science-and-healthcare/apc/dust-collector-safety-featurespng.png?h=570&iar=0&mw=760&w=760&rev=bfaa20bcdeaa4ce391f0a9af6a89d3f7&placeholder=pixelated&hash=01FC8FD91B670E52C18E9967B172C38F" class="img-fluid u-lazyAnimated" alt="" width="760" height="570" data-src="/-/media/images/qbank/__web/insight/life-science-and-healthcare/apc/dust-collector-safety-featurespng.png?rev=bfaa20bcdeaa4ce391f0a9af6a89d3f7&iar=0&mw=760&h=570&w=760&hash=BCF4270F108312999EC1C2C7223225BA" /> <!-- LinkedImage end Image --> <!-- LinkedImage end --> </div> </div> </div> <!-- TextAndImageInTwoColumns end --> <div class="col-12 "> <h3 class="u-heading"> Harmful substances &amp; exposure risks </h3> </div> <!-- TextAndImageInTwoColumns start --> <div class="TextAndImageInTwoColumns col-12 mb-4"> <div class="row"> <div class="col-12 col-md-6 "> <div class="TextAndImageInTwoColumns-text"> <div> Controlling toxic and combustible dust is a common, yet serious, challenge when manufacturing or processing pharmaceutical and chemical products. Everyday processes like mixing, conveying, blending and tableting create dangerous dusts that become airborne if not captured, extracted and contained thoroughly.<br /><br />The more potent the dust (OEB - Occupational Exposure Band), the lower the Occupational Exposure Limits (OEL) are set for personnel coming into contact with these materials. It is the employers’ responsibility to know and understand these exposure limits for each product they are using and take the necessary steps to ensure the limits are not exceeded, in order to protect their operators and the environment.&nbsp;&nbsp; </div> </div> </div> <div class="TextAndImageInTwoColumns-image col-12 col-md-6 "> <!-- LinkedImage start --> <!-- LinkedImage start Image --> <img src="/-/media/images/qbank/__web/industries/application-images_frequent/a-containment1.jpg?h=570&iar=0&mw=760&w=760&rev=70a60b6c063748a6b18e72c440acb870&placeholder=pixelated&hash=D5B3742C74FD902903457C8DA6CDB4A7" class="img-fluid u-lazyAnimated" alt="" width="760" height="570" data-src="/-/media/images/qbank/__web/industries/application-images_frequent/a-containment1.jpg?rev=70a60b6c063748a6b18e72c440acb870&iar=0&mw=760&h=570&w=760&hash=BEAD91E559D9988C37A835CA0E1C287E" /> <!-- LinkedImage end Image --> <!-- LinkedImage end --> </div> </div> </div> <!-- TextAndImageInTwoColumns end --> <div class="col-12 "> <h3 class="u-heading"> Containment solutions: how to protect operators, processes and the environment from harmful emissions </h3> </div> <!-- RichText start --> <div class="RichText col-12 mb-4"> <div> Especially in highly potent applications or in multi-product manufacturing facilities where cross-contamination is a concern, containment solutions are mandatory to ensure that dust doesn’t escape during normal operation as well as during routine service and maintenance work on the extraction system. Different options are available to mitigate exposure and explosion risks: </div> </div> <!-- RichText end --> <div class="col-12"> <div class="row"> <div id="camY2NjZjkwNEEwMHcxQjY0OTYwOGE0OWE0" class="camfil-col col-12 col-md-3 "> <div class="row "> <!-- PromoCard start --> <div class="PromoCard col-12 pb-4 mb-4"> <a class="card PromoCard-item PromoCard-link card-link"> <div class="position-relative PromoCard-imgWrap"> <img src="/-/media/images/qbank/__web/insight/life-science-and-healthcare/apc/dual-valvepromo-box2000x1500png.png?iar=0&mw=870&w=870&rev=c08f4d89dd2c4bc7860425efd6580354&mode=crop&heightratio=0.75&placeholder=pixelated&hash=DD6E7E89888A60068E9778A988257E89" class="card-img-top u-lazyAnimated" alt="" data-src="/-/media/images/qbank/__web/insight/life-science-and-healthcare/apc/dual-valvepromo-box2000x1500png.png?mode=crop&rev=c08f4d89dd2c4bc7860425efd6580354&iar=0&mw=870&w=870&heightratio=0.75&hash=A92481971601DA5552A166FEF31BF288" /> </div> <div class="PromoCard-cardBody card-body"> <h5 class="PromoCard-title u-heading"> Dual valve </h5> <div class="PromoCard-card-text card-text mb-3"> The Dual Valve is a dust discharge system intended to be used on dry dust collectors and similar equipment where there are high requirements for explosion protection and safe handling of harmful dust. The system transports the medium and fine dust from the collector to a bag or a continuous liner system, without interrupting the process and maintaining the pressure inside the dust collector. </div> <span class="u-heading"></span> </div> </a> </div> <!-- PromoCard end --> </div> </div> <divid ="camY2NjZjkwNEEwMHcxQjY0OTYwOGE0OWE1" class="camfil-col col-12 col-md-3 "> <div class="row "> <!-- PromoCard start --> <div class="PromoCard col-12 pb-4 mb-4"> <a class="card PromoCard-item PromoCard-link card-link"> <div class="position-relative PromoCard-imgWrap"> <img src="/-/media/images/qbank/__web/insight/life-science-and-healthcare/apc/continuous-liner-dischargepng.png?iar=0&mw=870&w=870&rev=bcfb8d1378844e1b93a28a00a14e8f7f&mode=crop&heightratio=0.75&placeholder=pixelated&hash=048F4E0042791C2637DEBE8551168C9C" class="card-img-top u-lazyAnimated" alt="" data-src="/-/media/images/qbank/__web/insight/life-science-and-healthcare/apc/continuous-liner-dischargepng.png?mode=crop&rev=bcfb8d1378844e1b93a28a00a14e8f7f&iar=0&mw=870&w=870&heightratio=0.75&hash=68E18082104AF4475E714C17A503F621" /> </div> <div class="PromoCard-cardBody card-body"> <h5 class="PromoCard-title u-heading"> Continuous liner system&#160; </h5> <div class="PromoCard-card-text card-text mb-3"> The continuous liner technology is used at the discharge system to contain the dust released from the cartridges to the hopper during automatic pulse-cleaning of the system. The collected dust must be taken away without any operative intervention with the bag or liner contents. The use of a continuous bag that is clamped in place and extended between each batch ensure safety. </div> <span class="u-heading"></span> </div> </a> </div> <!-- PromoCard end --> </div> </divid> <div id="camY2NjZjkwNEEwMHcxQjY0OTYwOGE0OWE2" class="camfil-col col-12 col-md-3 "> <div class="row "> <!-- PromoCard start --> <div class="PromoCard col-12 pb-4 mb-4"> <a class="card PromoCard-item PromoCard-link card-link"> <div class="position-relative PromoCard-imgWrap"> <img src="/-/media/images/qbank/__web/insight/life-science-and-healthcare/apc/bibo-gscpng.png?iar=0&mw=870&w=870&rev=c7d1775d823a4b46bc5614ae4a85cc18&mode=crop&heightratio=0.75&placeholder=pixelated&hash=28861F0C5EC082AB85CD36EC541C1D6F" class="card-img-top u-lazyAnimated" alt="" data-src="/-/media/images/qbank/__web/insight/life-science-and-healthcare/apc/bibo-gscpng.png?mode=crop&rev=c7d1775d823a4b46bc5614ae4a85cc18&iar=0&mw=870&w=870&heightratio=0.75&hash=5A2D202617BB96A78BC5B50A51E7DD80" /> </div> <div class="PromoCard-cardBody card-body"> <h5 class="PromoCard-title u-heading"> Bibo system </h5> <div class="PromoCard-card-text card-text mb-3"> When handling potent dusts, there should be a specific and integral safe change option, for both the filter elements as well as the dust discharge system (for safe disposal of the collected dust). The so called Bag-In/Bag-Out technology is used to prevent operator exposure and the collected material from escaping when performing filter change-outs. &nbsp; </div> <span class="u-heading"></span> </div> </a> </div> <!-- PromoCard end --> </div> </div> <div id="camY2NjZjkwNEEwMHcxQjY0OTYwOGE0OWE3" class="camfil-col col-12 col-md-3 "> <div class="row "> <!-- PromoCard start --> <div class="PromoCard col-12 pb-4 mb-4"> <a class="card PromoCard-item PromoCard-link card-link"> <div class="position-relative PromoCard-imgWrap"> <img src="/-/media/images/qbank/__web/insight/life-science-and-healthcare/apc/suppressionpharmajpg.jpg?iar=0&mw=870&w=623&rev=a61bc27cb0764f339451b05bc45f54c2&mode=crop&heightratio=0.75&placeholder=pixelated&hash=2D6821F6C658B1CBCDBCF4ED941A46DC" class="card-img-top u-lazyAnimated" alt="" 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</xml><![endif]--><!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Normale Tabelle"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin-top:0cm; mso-para-margin-right:0cm; mso-para-margin-bottom:8.0pt; mso-para-margin-left:0cm; line-height:107%; mso-pagination:widow-orphan; font-size:11.0pt; mso-bidi-font-size:10.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Mangal; mso-bidi-theme-font:minor-bidi;} </style> <![endif]--><p class="MsoNormal"><span style="mso-ansi-language:EN-US" lang="EN-US">To prevent outdoor or off-property exposure in the event of a dust explosion of potent compounds, either chemical suppression or containment designs for explosion and isolation valves are preferable to venting. The reason why is because these two protection options do not release materials to the environment.</span></p> </div> <span class="u-heading"></span> </div> </a> </div> <!-- PromoCard end --> </div> </div> </div> </div> <!-- RichText start --> <div class="RichText col-12 mb-5 mb-lg-7"> <div> <strong>Full training and continuous refreshing of procedures is important and Camfil have a range of tools available for this.&nbsp;</strong><br class="t-last-br" /> </div> </div> <!-- RichText end --> <div class="SelectedProductsListing col-12 mb-3 mb-5 mb-lg-7"> <div class="row"> <div class="col-12 text-center"> <h2 class="SelectedProductsListing-title u-heading mb-2"> Dust collectors for pharmaceutical manufacturing processes </h2> <p class="SelectedProductsListing-intro mb-0"> </p> </div> <div class="col-12"> <ul class="list-unstyled d-flex justify-content-center row flex-wrap mt-5 mb-0"> <li class="col-6 col-sm-4 col-md-3 mb-4"> <a href="/en-sg/products/dust-fume-and-mist-collectors/dry-dust-and-fume-collectors/quad-pulse-package-series/quad-pulse-package-i-_-46171" class="SelectedProductsListing-link"> <div class="SelectedProductsListing-imageWrapper p-3 mb-3"> <div class="SelectedProductsListing-imageOverlay"> <span class="btn btn-outline-light SelectedProductsListing-imageOverlayBtn"> Show product </span> </div> <img src="https://www.camfil.com/dam/images/18732/1186864/QPP1.png?width=300&height=300&bgcolor=white&placeholder=pixelated" data-src="https://www.camfil.com/dam/images/18732/1186864/QPP1.png?width=300&height=300&bgcolor=white" class="d-block mx-auto img-fluid u-lazyAnimated SelectedProductsListing-image" alt="QPP1" /> </div> <h2 class="SelectedProductsListing-productName"> Quad Pulse Package I </h2> <ul class="SelectedProductsListing-productFeatureList"> <li class="my-2">1 filter cartridge, air volume up to 1,200 m&#179;/h (706 cfm) </li> <li class="my-2">Online pulse cleaning without interrupting operations</li> <li class="my-2">Long filter life</li> <li class="my-2">Bag-In/Bag-Out safe-change for filters and dust discharge</li> <li class="my-2">Integrated explosion protection (ATEX certified)</li> <li class="my-2">Easy installation</li> <li class="my-2">High-Vacuum applications</li> </ul> </a> </li> <li class="col-6 col-sm-4 col-md-3 mb-4"> <a href="/en-sg/products/dust-fume-and-mist-collectors/dry-dust-and-fume-collectors/quad-pulse-package-series/quad-pulse-package-ii-_-46367" class="SelectedProductsListing-link"> <div class="SelectedProductsListing-imageWrapper p-3 mb-3"> <div class="SelectedProductsListing-imageOverlay"> <span class="btn btn-outline-light SelectedProductsListing-imageOverlayBtn"> Show product </span> </div> <img src="https://www.camfil.com/dam/images/13227/1186974/QPP2.png?width=300&height=300&bgcolor=white&placeholder=pixelated" data-src="https://www.camfil.com/dam/images/13227/1186974/QPP2.png?width=300&height=300&bgcolor=white" class="d-block mx-auto img-fluid u-lazyAnimated SelectedProductsListing-image" alt="Quad Pulse Package 2 Product Image" /> </div> <h2 class="SelectedProductsListing-productName"> Quad Pulse Package II </h2> <ul class="SelectedProductsListing-productFeatureList"> <li class="my-2">2 filter cartridges, air volume up to 3,000 m&#179;/h (1,765 cfm) </li> <li class="my-2">Online pulse cleaning without interrupting operations</li> <li class="my-2">Long filter life</li> <li class="my-2">Bag-In/Bag-Out safe-change for filters and dust discharge</li> <li class="my-2">ATEX explosion protection certified to category 1</li> <li class="my-2">Easy installation</li> <li class="my-2">High-vacuum applications</li> </ul> </a> </li> <li class="col-6 col-sm-4 col-md-3 mb-4"> <a href="/en-sg/products/dust-fume-and-mist-collectors/dry-dust-and-fume-collectors/gold-series/gold-series-camtain-_-46138" class="SelectedProductsListing-link"> <div class="SelectedProductsListing-imageWrapper p-3 mb-3"> <div class="SelectedProductsListing-imageOverlay"> <span class="btn btn-outline-light SelectedProductsListing-imageOverlayBtn"> Show product </span> </div> <img src="https://www.camfil.com/dam/images/17771/1281092/Gold-Series-Camtain.png?width=300&height=300&bgcolor=white&placeholder=pixelated" data-src="https://www.camfil.com/dam/images/17771/1281092/Gold-Series-Camtain.png?width=300&height=300&bgcolor=white" class="d-block mx-auto img-fluid u-lazyAnimated SelectedProductsListing-image" alt="Gold Series Camtain.png" /> </div> <h2 class="SelectedProductsListing-productName"> Gold Series Camtain </h2> <ul class="SelectedProductsListing-productFeatureList"> <li class="my-2">Bag-In/Bag-Out safe-change for filters and continuous liner system for dust discharge</li> <li class="my-2">Modular system available for larger air volumes</li> <li class="my-2">Cartridges using HemiPleat filter technology</li> <li class="my-2">High-efficiency filters up to E12 99.5% at MPPS, or greater than 95% at ePM1</li> <li class="my-2">Specially treated filter media repels fine particulates for a lower pressure drop and longer filter life</li> </ul> </a> </li> </ul> </div> </div> </div> <div class="col-12"> <div class="row"> <div id="camY2NjZjkwNEEwMHcxQjY0OTYwZTQ0YWU0" class="camfil-col col-md-6 "> <div class="row "> <!-- RichText start --> <div class="RichText col-12 mb-5 mb-lg-7"> <div> <p><strong>Explore content</strong></p> <ul> <li><a href="https://www.camfil.com/en/insights/life-science-and-healthcare" target="">More pharma related articles</a></li> <li><a href="https://www.camfil.com/en/industries/life-science/pharmaceutical--osd-manufacturing" target="">Industry information pharmaceutical</a></li> <li><a href="https://www.camfil.com/en/support-and-services/support/camfil-city#/" target="">Camfil City</a></li> </ul> </div> </div> <!-- RichText end --> </div> </div> <div id="camY2NjZjkwNEEwMHcxQjY0OTYwZTQ0YWU1" class="camfil-col col-md-6 "> <div class="row "> <!-- LinkButton start 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