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<!DOCTYPE html> <html xmlns="http://www.w3.org/1999/xhtml" lang="en" xml:lang="en"> <head>  <script async src="https://www.googletagmanager.com/gtag/js?id=G-WVK41JBQ8K"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-WVK41JBQ8K'); </script> <meta http-equiv="Content-Type" content="text/html;charset=utf-8" /> <title>Hepatitis C Online</title>  <link href="https://fonts.googleapis.com/css?family=Open+Sans:400,400i,600,600i,700,700i&subset=latin-ext" rel="stylesheet"> <link rel="stylesheet" href="//cdn.hepatitisc.uw.edu/css/vendors.css?v=bmhjdmMtbWFzdGVyLWM4ODQzNjczLTIwMjQtMTEtMTMtMjA1NjI0Cg" type="text/css" media="screen,print" /> <link rel="stylesheet" href="//cdn.hepatitisc.uw.edu/css/dynamic.css.php?v=bmhjdmMtbWFzdGVyLWM4ODQzNjczLTIwMjQtMTEtMTMtMjA1NjI0Cg" type="text/css" media="screen,print" /> <link rel="stylesheet" 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src="//cdn.hepatitisc.uw.edu/scripts/min/vendors-min.js?v=bmhjdmMtbWFzdGVyLWM4ODQzNjczLTIwMjQtMTEtMTMtMjA1NjI0Cg"></script> <script type="text/javascript" src="//cdn.hepatitisc.uw.edu/scripts/min/scripts-min.js?v=bmhjdmMtbWFzdGVyLWM4ODQzNjczLTIwMjQtMTEtMTMtMjA1NjI0Cg"></script> <link rel="apple-touch-icon" sizes="180x180" href="//cdn.hepatitisc.uw.edu/css/images/ios/logo.png" /><meta name="theme-color" content="#4b5c84"> </head> <body class="site-nhcvc logged-out front action- not-mobile use-questions"> <section id="header-components"><div id="header"><div class="inner"><a href="/process.php?action=home" id="logo">Hepatitis C Online</a></div></div><div class="nav-outer"><div class="level1-navigation"><div class="inner"><ul class="main-menu"><li class="section section-menu visible-mobile"><div class="link"><span class="menu-open glyphicon glyphicon-th" aria-hidden="true"></span><span class="menu-close glyphicon glyphicon-remove" aria-hidden="true"></span> <span class="hidden">Site Navigation</span></div></li><li class="section home-section"><a href="/" title="Hepatitis C Online" class=" link"></a></li><li class="section biology"><a href="/page/hcv/biology" class="link ">HCV <br />Biology</a></li><li class="section treatments nhcvc-medications has-submenu"><a href="/page/treatment/drugs" class=" link ">HCV <br />Medications<span class="submenu-trigger"></span></a><div class="submenu medications"><div class="description description-default">Listed in <strong>alphabetical</strong> order.</div><ul><li class="treatment treatment-7"><a href="/page/treatment/drugs/elbasvir-grazoprevir"><img class="drug-preview" src="//cdn.hepatitisc.uw.edu/css/images/drugs/7.png" alt="Elbasvir-Grazoprevir (Zepatier) Pill Preview" />Elbasvir-Grazoprevir <em>Zepatier</em></a></li><li class="treatment treatment-22"><a href="/page/treatment/drugs/glecaprevir-pibrentasvir"><img class="drug-preview" src="//cdn.hepatitisc.uw.edu/css/images/drugs/22.png" alt="Glecaprevir-Pibrentasvir (Mavyret) Pill Preview" />Glecaprevir-Pibrentasvir <em>Mavyret</em></a></li><li class="treatment treatment-11"><a href="/page/treatment/drugs/ledipasvir-sofosbuvir"><img class="drug-preview" src="//cdn.hepatitisc.uw.edu/css/images/drugs/11.png" alt="Ledipasvir-Sofosbuvir (Harvoni) Pill Preview" />Ledipasvir-Sofosbuvir <em>Harvoni</em></a></li><li class="treatment treatment-3"><a href="/page/treatment/drugs/ribavirin-drug"><img class="drug-preview" src="//cdn.hepatitisc.uw.edu/css/images/drugs/3.png" alt="Ribavirin (Copegus, Rebetol, Ribasphere) Pill Preview" />Ribavirin <em>Copegus, Rebetol, Ribasphere</em></a></li><li class="treatment treatment-1"><a href="/page/treatment/drugs/sofosbuvir-drug"><img class="drug-preview" src="//cdn.hepatitisc.uw.edu/css/images/drugs/1.png" alt="Sofosbuvir (Sovaldi) Pill Preview" />Sofosbuvir <em>Sovaldi</em></a></li><li class="treatment treatment-20"><a href="/page/treatment/drugs/epclusa"><img class="drug-preview" src="//cdn.hepatitisc.uw.edu/css/images/drugs/20.png" alt="Sofosbuvir-Velpatasvir (Epclusa) Pill Preview" />Sofosbuvir-Velpatasvir <em>Epclusa</em></a></li><li class="treatment treatment-21"><a href="/page/treatment/drugs/sofosbuvir-velpatasvir-voxilaprevir"><img class="drug-preview" src="//cdn.hepatitisc.uw.edu/css/images/drugs/21.png" alt="Sofosbuvir-Velpatasvir-Voxilaprevir (Vosevi) Pill Preview" />Sofosbuvir-Velpatasvir-Voxilaprevir <em>Vosevi</em></a></li></ul></div></li><li class="section modules has-submenu"><a href="/alternate" class="link ">Course <br /> Modules<span class="submenu-trigger"></span></a><div class="submenu modules"><ul><li class="level1 level1-all "><a href="/alternate"><span class="caption">View all Course Modules</span></a></li><li class="level1 level1-31 has-subsubmenu"><a href="/go/screening-diagnosis"><span class="num">1</span><span class="caption">Screening and Diagnosis of Hepatitis C Infection</span><span class="submenu-trigger"></span></a><div class="subsubmenu custom"><a class="description" href="/custom/screening-diagnosis"><h3>Self-Study Module<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME Available</span></h3> Track your progress and receive CE credit</a><ul><li><a href="/custom/screening-diagnosis">Screening and Diagnosis: Self-Study <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-108"><a href="/custom/screening-diagnosis/epidemiology-us"><span class="caption">HCV Epidemiology in the United States</span></a></li><li class="level2 level2-109"><a href="/custom/screening-diagnosis/recommendations-screening"><span class="caption">Recommendations for Hepatitis C Screening</span></a></li><li class="level2 level2-110"><a href="/custom/screening-diagnosis/diagnostic-testing"><span class="caption">Hepatitis C Diagnostic Testing</span></a></li><li class="level2 level2-111"><a href="/custom/screening-diagnosis/counseling-prevention"><span class="caption">Counseling for Prevention of HCV Transmission</span></a></li><li class="level2 level2-112"><a href="/custom/screening-diagnosis/acute-diagnosis"><span class="caption">Diagnosis of Acute HCV Infection</span></a></li></ol><ul><li><a href="/custom/screening-diagnosis/certificate">Certificate Requirements <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul></div><div class="subsubmenu level2s"><a class="description" href="/go/screening-diagnosis"><h3>Quick Reference<span class="edition-tag edition-tag-4">4th Edition</span></h3> Rapidly access information in this module</a><ul><li><a href="/go/screening-diagnosis">Screening and Diagnosis of Hepatitis C Infection: Overview</a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-153"><a href="/go/screening-diagnosis/epidemiology-us/core-concept/all"><span class="caption">HCV Epidemiology in the United States</span></a></li><li class="level2 level2-157"><a href="/go/screening-diagnosis/recommendations-screening/core-concept/all"><span class="caption">Recommendations for Hepatitis C Screening</span></a></li><li class="level2 level2-154"><a href="/go/screening-diagnosis/diagnostic-testing/core-concept/all"><span class="caption">Hepatitis C Diagnostic Testing</span></a></li><li class="level2 level2-155"><a href="/go/screening-diagnosis/counseling-prevention/core-concept/all"><span class="caption">Counseling for Prevention of HCV Transmission</span></a></li><li class="level2 level2-156"><a href="/go/screening-diagnosis/acute-diagnosis/core-concept/all"><span class="caption">Diagnosis of Acute HCV Infection</span></a></li></ol></div></li><li class="level1 level1-34 has-subsubmenu"><a href="/go/evaluation-staging-monitoring"><span class="num">2</span><span class="caption">Evaluation, Staging, and Monitoring of Chronic Hepatitis C</span><span class="submenu-trigger"></span></a><div class="subsubmenu custom"><a class="description" href="/custom/evaluation-staging-monitoring"><h3>Self-Study Module<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME Available</span></h3> Track your progress and receive CE credit</a><ul><li><a href="/custom/evaluation-staging-monitoring">Evaluation, Staging, and Monitoring: Self-Study <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-124"><a href="/custom/evaluation-staging-monitoring/initial-evaluation-chronic"><span class="caption">Initial Evaluation of Persons with Chronic HCV</span></a></li><li class="level2 level2-125"><a href="/custom/evaluation-staging-monitoring/natural-history"><span class="caption">Natural History of HCV Infection</span></a></li><li class="level2 level2-126"><a href="/custom/evaluation-staging-monitoring/counseling-liver-health"><span class="caption">Counseling Persons with Chronic HCV Infection</span></a></li><li class="level2 level2-127"><a href="/custom/evaluation-staging-monitoring/evaluation-staging"><span class="caption">Evaluation and Staging of Liver Fibrosis</span></a></li><li class="level2 level2-128"><a href="/custom/evaluation-staging-monitoring/evaluation-prognosis-cirrhosis"><span class="caption">Evaluation and Prognosis of Persons with Cirrhosis</span></a></li><li class="level2 level2-129"><a href="/custom/evaluation-staging-monitoring/surveillance-hepatocellular-carcinoma"><span class="caption">Surveillance for Hepatocellular Carcinoma</span></a></li><li class="level2 level2-130"><a href="/custom/evaluation-staging-monitoring/extrahepatic-conditions"><span class="caption">Extrahepatic Conditions Related to HCV Infection</span></a></li></ol><ul><li><a href="/custom/evaluation-staging-monitoring/certificate">Certificate Requirements <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul></div><div class="subsubmenu level2s"><a class="description" href="/go/evaluation-staging-monitoring"><h3>Quick Reference<span class="edition-tag edition-tag-4">4th Edition</span></h3> Rapidly access information in this module</a><ul><li><a href="/go/evaluation-staging-monitoring">Evaluation, Staging, and Monitoring of Chronic Hepatitis C: Overview</a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-169"><a href="/go/evaluation-staging-monitoring/initial-evaluation-chronic/core-concept/all"><span class="caption">Initial Evaluation of Persons with Chronic HCV</span></a></li><li class="level2 level2-170"><a href="/go/evaluation-staging-monitoring/natural-history/core-concept/all"><span class="caption">Natural History of HCV Infection</span></a></li><li class="level2 level2-171"><a href="/go/evaluation-staging-monitoring/counseling-liver-health/core-concept/all"><span class="caption">Counseling Persons with Chronic HCV Infection</span></a></li><li class="level2 level2-172"><a href="/go/evaluation-staging-monitoring/evaluation-staging/core-concept/all"><span class="caption">Evaluation and Staging of Liver Fibrosis</span></a></li><li class="level2 level2-175"><a href="/go/evaluation-staging-monitoring/evaluation-prognosis-cirrhosis/core-concept/all"><span class="caption">Evaluation and Prognosis of Persons with Cirrhosis</span></a></li><li class="level2 level2-173"><a href="/go/evaluation-staging-monitoring/surveillance-hepatocellular-carcinoma/core-concept/all"><span class="caption">Surveillance for Hepatocellular Carcinoma</span></a></li><li class="level2 level2-174"><a href="/go/evaluation-staging-monitoring/extrahepatic-conditions/core-concept/all"><span class="caption">Extrahepatic Conditions Related to HCV Infection</span></a></li></ol></div></li><li class="level1 level1-33 has-subsubmenu"><a href="/go/management-cirrhosis-related-complications"><span class="num">3</span><span class="caption">Management of Cirrhosis-Related Complications</span><span class="submenu-trigger"></span></a><div class="subsubmenu custom"><a class="description" href="/custom/management-cirrhosis-related-complications"><h3>Self-Study Module<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME Available</span></h3> Track your progress and receive CE credit</a><ul><li><a href="/custom/management-cirrhosis-related-complications">Management of Cirrhosis-Related Complications: Self-Study <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-119"><a href="/custom/management-cirrhosis-related-complications/ascites-diagnosis-management"><span class="caption">Diagnosis and Management of Ascites</span></a></li><li class="level2 level2-120"><a href="/custom/management-cirrhosis-related-complications/spontaneous-bacterial-peritonitis-recognition-management"><span class="caption">Recognition and Management of Spontaneous Bacterial Peritonitis</span></a></li><li class="level2 level2-121"><a href="/custom/management-cirrhosis-related-complications/varices-screening-prevention-bleeding"><span class="caption">Screening for Varices and Prevention of Bleeding</span></a></li><li class="level2 level2-122"><a href="/custom/management-cirrhosis-related-complications/hepatic-encephalopathy-diagnosis-management"><span class="caption">Diagnosis and Management of Hepatic Encephalopathy</span></a></li><li class="level2 level2-123"><a href="/custom/management-cirrhosis-related-complications/liver-transplantation-referral"><span class="caption">Referral for Liver Transplantation</span></a></li></ol><ul><li><a href="/custom/management-cirrhosis-related-complications/certificate">Certificate Requirements <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul></div><div class="subsubmenu level2s"><a class="description" href="/go/management-cirrhosis-related-complications"><h3>Quick Reference<span class="edition-tag edition-tag-4">4th Edition</span></h3> Rapidly access information in this module</a><ul><li><a href="/go/management-cirrhosis-related-complications">Management of Cirrhosis-Related Complications: Overview</a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-164"><a href="/go/management-cirrhosis-related-complications/ascites-diagnosis-management/core-concept/all"><span class="caption">Diagnosis and Management of Ascites</span></a></li><li class="level2 level2-165"><a href="/go/management-cirrhosis-related-complications/spontaneous-bacterial-peritonitis-recognition-management/core-concept/all"><span class="caption">Recognition and Management of Spontaneous Bacterial Peritonitis</span></a></li><li class="level2 level2-166"><a href="/go/management-cirrhosis-related-complications/varices-screening-prevention-bleeding/core-concept/all"><span class="caption">Screening for Varices and Prevention of Bleeding</span></a></li><li class="level2 level2-167"><a href="/go/management-cirrhosis-related-complications/hepatic-encephalopathy-diagnosis-management/core-concept/all"><span class="caption">Diagnosis and Management of Hepatic Encephalopathy</span></a></li><li class="level2 level2-168"><a href="/go/management-cirrhosis-related-complications/liver-transplantation-referral/core-concept/all"><span class="caption">Referral for Liver Transplantation</span></a></li></ol></div></li><li class="level1 level1-35 has-subsubmenu"><a href="/go/evaluation-treatment"><span class="num">4</span><span class="caption">Evaluation and Preparation for Hepatitis C Treatment</span><span class="submenu-trigger"></span></a><div class="subsubmenu custom"><a class="description" href="/custom/evaluation-treatment"><h3>Self-Study Module<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME Available</span></h3> Track your progress and receive CE credit</a><ul><li><a href="/custom/evaluation-treatment">Evaluation and Preparation for Treatment: Self-Study <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-131"><a href="/custom/evaluation-treatment/treatment-goals-predicting-response"><span class="caption">Goals and Benefits with HCV Treatment</span></a></li><li class="level2 level2-132"><a href="/custom/evaluation-treatment/treatment-initiation-decision"><span class="caption">Making a Decision on When to Initiate HCV Therapy</span></a></li><li class="level2 level2-133"><a href="/custom/evaluation-treatment/addressing-structural-barriers-to-treatment"><span class="caption">Addressing Structural Barriers to HCV Treatment</span></a></li></ol><ul><li><a href="/custom/evaluation-treatment/certificate">Certificate Requirements <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul></div><div class="subsubmenu level2s"><a class="description" href="/go/evaluation-treatment"><h3>Quick Reference<span class="edition-tag edition-tag-4">4th Edition</span></h3> Rapidly access information in this module</a><ul><li><a href="/go/evaluation-treatment">Evaluation and Preparation for Hepatitis C Treatment: Overview</a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-176"><a href="/go/evaluation-treatment/treatment-goals-predicting-response/core-concept/all"><span class="caption">Goals and Benefits with HCV Treatment</span></a></li><li class="level2 level2-177"><a href="/go/evaluation-treatment/treatment-initiation-decision/core-concept/all"><span class="caption">Making a Decision on When to Initiate HCV Therapy</span></a></li><li class="level2 level2-178"><a href="/go/evaluation-treatment/addressing-structural-barriers-to-treatment/core-concept/all"><span class="caption">Addressing Structural Barriers to HCV Treatment</span></a></li></ol></div></li><li class="level1 level1-30 has-subsubmenu"><a href="/go/treatment-infection"><span class="num">5</span><span class="caption">Treatment of Hepatitis C Infection</span><span class="submenu-trigger"></span></a><div class="subsubmenu custom"><a class="description" href="/custom/treatment"><h3>Self-Study Module<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME Available</span></h3> Track your progress and receive CE credit</a><ul><li><a href="/custom/treatment">Treatment of HCV: Self-Study <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-102"><a href="/custom/treatment/multi-genotype-treatment-new-lesson"><span class="caption">Simplified HCV Treatment for All HCV Genotypes</span></a></li><li class="level2 level2-103"><a href="/custom/treatment/retreatment-patients-prior-treatment-experience"><span class="caption">Retreatment of Patients with Prior HCV Treatment Experience</span></a></li><li class="level2 level2-101"><a href="/custom/treatment/monitoring"><span class="caption">Monitoring During and After HCV Treatment</span></a></li><li class="level2 level2-105"><a href="/custom/treatment/treatment-cirrhosis"><span class="caption">Treatment of HCV in Persons with Cirrhosis</span></a></li><li class="level2 level2-104"><a href="/custom/treatment/treatment-acute-infection"><span class="caption">Treatment of Acute HCV Infection</span></a></li></ol><ul><li><a href="/custom/treatment/certificate">Certificate Requirements <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul></div><div class="subsubmenu level2s"><a class="description" href="/go/treatment-infection"><h3>Quick Reference<span class="edition-tag edition-tag-4">4th Edition</span></h3> Rapidly access information in this module</a><ul><li><a href="/go/treatment-infection">Treatment of Hepatitis C Infection: Overview</a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-149"><a href="/go/treatment-infection/multi-genotype-treatment-new-lesson/core-concept/all"><span class="caption">Simplified HCV Treatment for All HCV Genotypes</span></a></li><li class="level2 level2-150"><a href="/go/treatment-infection/retreatment-patients-prior-treatment-experience/core-concept/all"><span class="caption">Retreatment of Patients with Prior HCV Treatment Experience</span></a></li><li class="level2 level2-143"><a href="/go/treatment-infection/monitoring/core-concept/all"><span class="caption">Monitoring During and After HCV Treatment</span></a></li><li class="level2 level2-152"><a href="/go/treatment-infection/treatment-cirrhosis/core-concept/all"><span class="caption">Treatment of HCV in Persons with Cirrhosis</span></a></li><li class="level2 level2-151"><a href="/go/treatment-infection/treatment-acute-infection/core-concept/all"><span class="caption">Treatment of Acute HCV Infection</span></a></li></ol></div></li><li class="level1 level1-32 has-subsubmenu"><a href="/go/key-populations-situations"><span class="num">6</span><span class="caption">Treatment of Key Populations and Unique Situations</span><span class="submenu-trigger"></span></a><div class="subsubmenu custom"><a class="description" href="/custom/key-populations-unique-situations"><h3>Self-Study Module<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME Available</span></h3> Track your progress and receive CE credit</a><ul><li><a href="/custom/key-populations-unique-situations">Treatment of Key Populations and Unique Situations: Self-Study <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-113"><a href="/custom/key-populations-unique-situations/treatment-hiv-coinfection"><span class="caption">Treatment of HCV in Persons with HIV Coinfection</span></a></li><li class="level2 level2-114"><a href="/custom/key-populations-unique-situations/treament-renal-impairment"><span class="caption">Treatment of HCV in Persons with Renal Impairment</span></a></li><li class="level2 level2-115"><a href="/custom/key-populations-unique-situations/treatment-substance-use"><span class="caption">Treatment of HCV in Persons with Substance Use</span></a></li><li class="level2 level2-116"><a href="/custom/key-populations-unique-situations/treatment-corrections"><span class="caption">Treatment of HCV in a Correctional Setting</span></a></li><li class="level2 level2-117"><a href="/custom/key-populations-unique-situations/management-health-care-workers-potentially-exposed-to-hcv"><span class="caption">Management of Health Care Personnel Exposed to HCV</span></a></li><li class="level2 level2-118"><a href="/custom/key-populations-unique-situations/perinatal-hcv-transmission"><span class="caption">Perinatal HCV Transmission</span></a></li></ol><ul><li><a href="/custom/key-populations-unique-situations/certificate">Certificate Requirements <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul></div><div class="subsubmenu level2s"><a class="description" href="/go/key-populations-situations"><h3>Quick Reference<span class="edition-tag edition-tag-4">4th Edition</span></h3> Rapidly access information in this module</a><ul><li><a href="/go/key-populations-situations">Treatment of Key Populations and Unique Situations: Overview</a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-158"><a href="/go/key-populations-situations/treatment-hiv-coinfection/core-concept/all"><span class="caption">Treatment of HCV in Persons with HIV Coinfection</span></a></li><li class="level2 level2-159"><a href="/go/key-populations-situations/treament-renal-impairment/core-concept/all"><span class="caption">Treatment of HCV in Persons with Renal Impairment</span></a></li><li class="level2 level2-160"><a href="/go/key-populations-situations/treatment-substance-use/core-concept/all"><span class="caption">Treatment of HCV in Persons with Substance Use</span></a></li><li class="level2 level2-161"><a href="/go/key-populations-situations/treatment-corrections/core-concept/all"><span class="caption">Treatment of HCV in a Correctional Setting</span></a></li><li class="level2 level2-162"><a href="/go/key-populations-situations/management-health-care-workers-potentially-exposed-to-hcv/core-concept/all"><span class="caption">Management of Health Care Personnel Exposed to HCV</span></a></li><li class="level2 level2-163"><a href="/go/key-populations-situations/perinatal-hcv-transmission/core-concept/all"><span class="caption">Perinatal HCV Transmission</span></a></li></ol></div></li></ul></div></li><li class="section tools has-submenu"><a href="/page/clinical-calculators/apri" class="link ">Tools &<br /> Calculators<span class="submenu-trigger"></span></a><div class="submenu tools"><ul><li class="section-page section-page-7 has-subsubmenu"><a href="/page/clinical-calculators/ctp" class=""><span class="caption">Clinical Calculators</span><span class="submenu-trigger"></span></a><div 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Equation</em></a></li><li class="tool"><a href="/page/clinical-calculators/meld" class="">MELD Calculator <em>Model for End-Stage Liver Disease (MELD) for ages 12 and older</em></a></li><li class="tool"><a href="/page/clinical-calculators/saag" class="">SAAG Calculator <em>Serum-Ascites Albumin Gradient (SAAG)</em></a></li></ul></div></li><li class="section-page section-page-14 has-subsubmenu"><a href="/page/substance-use/audit-c" class=""><span class="caption">Substance Use Screening Tools</span><span class="submenu-trigger"></span></a><div class="subsubmenu sections"><ul><li class="tool"><a href="/page/substance-use/audit-c" class="">Alcohol: AUDIT-C <em>Alcohol Use Disorders Identification Test (AUDIT-C)</em></a></li><li class="tool"><a href="/page/substance-use/cage" class="">Alcohol: CAGE <em>CAGE Alcohol Questionnaire</em></a></li><li class="tool"><a href="/page/substance-use/opioid" class="">Opioid: Risk Tool <em>Opioid Risk Tool (ORT)</em></a></li></ul></div></li></ul></div></li><li class="section ccn"><a href="/page/site/clinical-consultation" class="link has-tooltip">Clinical <br />Consultation</a></li><li class="section expert-opinions"><a href="/page/challenges/expert-opinions" class=" link "><span class="icon"><span class="glyphicon glyphicon-link"></span></span>Clinical <br />Challenges</a></li><li class="section mini-lectures"><a href="/mini-lectures" class="link">Mini-<br>Lectures</a></li><li class="section glossary"><a href="javascript:void(0)" title="Search for any topic" class="link ">Search</a><div id="search-minimal" class="search-interface"><div class="close"></div><div class="search-controls"><label for="search-q">Search for</label><input type="text" name="search-q" id="search-q" class="search-input" placeholder="Terms, medications, lectures, core concepts, etc..." /></div><div class="search-results-container"></div><div class="search-notice"><strong>Use this Search to quickly find items or navigate the site.</strong></div></div></li></ul><div class="user-status"><a class="loggedout" href="https://www.hepatitisC.uw.edu/alternate" title="Sign In for registered users"><span class="glyphicon glyphicon-log-in"></span><span class="label-text"> Sign In</span></a><span class="hidden-xs"> or <a class="loggedout" href="https://www.hepatitisC.uw.edu/page/account/register" title="Create an account">Register</a></span></div></div></div></div></section><div id="wrap" class="content-wrap"> <div id="content"> <div id="notifications"></div><div id="home-features" class="homepage/features"><div class="slider"><div class="inner"><div id="home-landing-about" class="homepage/features/about"><h1>Hepatitis C Online</h1><div class="about site/tag-line">A free educational website from the<br>University of Washington Infectious Diseases Education & Assessment (IDEA) program</div><div class="contributors overview"><a href="/page/site/contributors" class="button-contributors reading-pane"><i class="glyph-contributors"></i> Contributors</a></div><div class="funded-by">Funded by<div class="source">Centers for Disease Control and Prevention (CDC)</div></div></div> </div></div> <div class="content"><div class="feature-content feature-content-0"><h2 class="title">HCV Biology</h2><div class="text-content"><p><strong>HCV Structure<br /> HCV Proteins<br /> HCV Life Cycle</strong></p></div><a class="link" href="page/hcv/biology">Learn about HCV Biology »</a></div><div class="feature-content feature-content-1" featured-section="hcv-medications"><h2 class="title">HCV Medications</h2><div class="text-content"><div><strong>Medication Summaries<br /> Prescribing Information</strong><br /> <strong>Clinical Studies</strong></div> <div><strong>Slide Decks</strong></div></div><a class="link" href="page/treatment/drugs">Learn about medications to treat HCV »</a></div><div class="feature-content feature-content-2" featured-section="modules"><h2 class="title">Course Modules</h2><div class="text-content"><p><strong>Access to Quick Reference Information<br /> Track progress with Self-Study Modules<br /> Free CME credits and CNE/CE contact hours</strong></p></div><a class="link" href="alternate">Start the Self-Study Modules »</a></div><div class="feature-content feature-content-3" featured-section="tools"><h2 class="title title-long">Clinical Calculators</h2><div class="text-content"><b>APRI, AUDIT-C; BMI, CAGE;</b><br /> <b>CTP, MELD, SAAG,<br /> and more</b></div><a class="link" href="page/clinical-calculators/apri">Discover the Clinical Calculators »</a></div></div><ul class="nav"><li class="nav nav-0" data-id="0"><a>0</a></li><li class="nav nav-1" data-id="1"><a>1</a></li><li class="nav nav-2" data-id="2"><a>2</a></li><li class="nav nav-3" data-id="3"><a>3</a></li></ul></div><div id="home-structure-menu"><h1>HCV Course Modules</h1><div class="structure-overview"><div class="inner"><div class="row section section-31"><div class="col-xs-12 col-sm-4 col-title"><h2 style="color: rgb(7,71,132);"><a href="/go/screening-diagnosis" style="color: rgb(7,71,132);">Screening and Diagnosis of Hepatitis C Infection</a></h2><p class=""><small>For any clinician who may encounter persons with hepatitis C virus infection and would like to establish core competence in testing for hepatitis C, counseling patients on preventing hepatitis C transmission, and diagnosing acute hepatitis C infection.</small></p><br /></div><div class="col-xs-12 col-sm-8"> <div class="row"><div class="col-xs-6 col-ss"><h3><a href="/go/screening-diagnosis">Overview / Quick Reference <span class="glyphicon glyphicon-chevron-right"></span></a></h3><p class="text-muted">Rapidly access info about Screening and Diagnosis of Hepatitis C Infection</p><br /><hr /><h3><a href="/custom/screening-diagnosis">Self-Study<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME</span></a></h3><p class="text-muted">Track your progress and receive CE credit</p></div><div class="col-xs-6 col-qb col-eo"><h3><a href="/page/challenges/expert-opinions/screening-diagnosis">Clinical Challenges</a></h3><p class="text-muted">Expert opinions for challenging and controversial cases</p><br /></div></div></div></div><div class="row section section-34"><div class="col-xs-12 col-sm-4 col-title"><h2 style="color: rgb(143,108,13);"><a href="/go/evaluation-staging-monitoring" style="color: rgb(143,108,13);">Evaluation, Staging, and Monitoring of Chronic Hepatitis C</a></h2><p class=""><small>Intended for clinicians involved in long-term management of persons with chronic hepatitis C infection. Content includes initial evaluation, natural history, preventing liver damage, staging of liver fibrosis, evaluation of cirrhosis, surveillance for hepatocellular carcinoma, and recognition of extrahepatic manifestations.</small></p><br /></div><div class="col-xs-12 col-sm-8"> <div class="row"><div class="col-xs-6 col-ss"><h3><a href="/go/evaluation-staging-monitoring">Overview / Quick Reference <span class="glyphicon glyphicon-chevron-right"></span></a></h3><p class="text-muted">Rapidly access info about Evaluation, Staging, and Monitoring of Chronic Hepatitis C</p><br /><hr /><h3><a href="/custom/evaluation-staging-monitoring">Self-Study<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME</span></a></h3><p class="text-muted">Track your progress and receive CE credit</p></div><div class="col-xs-6 col-qb col-eo"><h3><a href="/page/challenges/expert-opinions/evaluation-staging-monitoring">Clinical Challenges</a></h3><p class="text-muted">Expert opinions for challenging and controversial cases</p><br /></div></div></div></div><div class="row section section-33"><div class="col-xs-12 col-sm-4 col-title"><h2 style="color: rgb(115,57,115);"><a href="/go/management-cirrhosis-related-complications" style="color: rgb(115,57,115);">Management of Cirrhosis-Related Complications</a></h2><p class=""><small>Addresses the diagnosis and management of complications that may arise in person with chronic HCV infection and cirrhosis, including ascites, spontaneous bacterial peritonitis, varicies, hepatic encephalopathy, and referral for liver transplantation.</small></p><br /></div><div class="col-xs-12 col-sm-8"> <div class="row"><div class="col-xs-6 col-ss"><h3><a href="/go/management-cirrhosis-related-complications">Overview / Quick Reference <span class="glyphicon glyphicon-chevron-right"></span></a></h3><p class="text-muted">Rapidly access info about Management of Cirrhosis-Related Complications</p><br /><hr /><h3><a href="/custom/management-cirrhosis-related-complications">Self-Study<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME</span></a></h3><p class="text-muted">Track your progress and receive CE credit</p></div><div class="col-xs-6 col-qb col-eo"><h3><a href="/page/challenges/expert-opinions/management-cirrhosis-related-complications">Clinical Challenges</a></h3><p class="text-muted">Expert opinions for challenging and controversial cases</p><br /></div></div></div></div><div class="row section section-35"><div class="col-xs-12 col-sm-4 col-title"><h2 style="color: rgb(190,54,39);"><a href="/go/evaluation-treatment" style="color: rgb(190,54,39);">Evaluation and Preparation for Hepatitis C Treatment</a></h2><p class=""><small>For clinicians evaluating persons with chronic HCV infection for hepatitis C treatment, including clinicians who will independently assess treatment candidacy and clinicians who will provide treatment candidacy with assistance from a hepatitis C expert.</small></p><br /></div><div class="col-xs-12 col-sm-8"> <div class="row"><div class="col-xs-6 col-ss"><h3><a href="/go/evaluation-treatment">Overview / Quick Reference <span class="glyphicon glyphicon-chevron-right"></span></a></h3><p class="text-muted">Rapidly access info about Evaluation and Preparation for Hepatitis C Treatment</p><br /><hr /><h3><a href="/custom/evaluation-treatment">Self-Study<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME</span></a></h3><p class="text-muted">Track your progress and receive CE credit</p></div><div class="col-xs-6 col-qb col-eo"><h3><a href="/page/challenges/expert-opinions/evaluation-treatment">Clinical Challenges</a></h3><p class="text-muted">Expert opinions for challenging and controversial cases</p><br /></div></div></div></div><div class="row section section-30"><div class="col-xs-12 col-sm-4 col-title"><h2 style="color: rgb(60,89,21);"><a href="/go/treatment-infection" style="color: rgb(60,89,21);">Treatment of Hepatitis C Infection</a></h2><p class=""><small>Reviews simplified HCV treatment for all HCV genotypes and how to treat persons with prior HCV treatment experience, cirrhosis, or acute HCV infection.</small></p><br /></div><div class="col-xs-12 col-sm-8"> <div class="row"><div class="col-xs-6 col-ss"><h3><a href="/go/treatment-infection">Overview / Quick Reference <span class="glyphicon glyphicon-chevron-right"></span></a></h3><p class="text-muted">Rapidly access info about Treatment of Hepatitis C Infection</p><br /><hr /><h3><a href="/custom/treatment">Self-Study<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME</span></a></h3><p class="text-muted">Track your progress and receive CE credit</p></div><div class="col-xs-6 col-qb col-eo"><h3><a href="/page/challenges/expert-opinions/treatment-infection">Clinical Challenges</a></h3><p class="text-muted">Expert opinions for challenging and controversial cases</p><br /></div></div></div></div><div class="row section section-32"><div class="col-xs-12 col-sm-4 col-title"><h2 style="color: rgb(19,149,186);"><a href="/go/key-populations-situations" style="color: rgb(19,149,186);">Treatment of Key Populations and Unique Situations</a></h2><p class=""><small>Designed for clinicians who manage key populations of persons living with HCV and/or complex HCV-related unique treatment issues. Material covered is at an advanced level.</small></p><br /></div><div class="col-xs-12 col-sm-8"> <div class="row"><div class="col-xs-6 col-ss"><h3><a href="/go/key-populations-situations">Overview / Quick Reference <span class="glyphicon glyphicon-chevron-right"></span></a></h3><p class="text-muted">Rapidly access info about Treatment of Key Populations and Unique Situations</p><br /><hr /><h3><a href="/custom/key-populations-unique-situations">Self-Study<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME</span></a></h3><p class="text-muted">Track your progress and receive CE credit</p></div><div class="col-xs-6 col-qb col-eo"><h3><a href="/page/challenges/expert-opinions/key-populations-situations">Clinical Challenges</a></h3><p class="text-muted">Expert opinions for challenging and controversial cases</p><br /></div></div></div></div></div></div></div><div id="home-page" class="alternate"><div class="inner"><div class="page page-news"><h2 class="title">News</h2> <a class="button-featured clearfix target-lightbox" href="/page/site/4th-edition"><strong>4th Edition Rollout Starts November 1st</strong><br />From November 2023 through Spring 2024, the 4<sup>th</sup> Edition of the six modules will roll out to start new 3-year accreditation periods. Learn more ></a><a class="button-featured clearfix target-lightbox" href="/page/site/ce-notices"><strong>Pharmacology CE now Available</strong><br />Pharmacology CE for advanced practice nurses is now available for <u>Modules 3, 4, 5, and 6</u> (as designated in the self-study lesson overview). <span class="cme-tag cme-tag-available">CNE</span></a><a class="button-featured clearfix target-lightbox" href="/page/help/2018-cme-launch"><strong>Note: Content Moved</strong><br />The topic Approach to Treatment in Persons with Substance Use has been moved to Module 6 and has been renamed Treatment of HCV in Persons with Substance Use</a> </div> <div class="page page-online-course"><h2 class="title">Take the Free Online Course</h2><p> Browse or create an account and track your progress as you work through the course.  After registering, you can obtain free CME or CNE credit.</p><div class="buttons"><a href="/alternate" class="button-browse">Browse the Course Modules</a> <a href="/alternate" onclick="loginShowWindow(); 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