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Nikethamide - Wikipedia

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href="https://azb.wikipedia.org/wiki/%D9%86%DB%8C%DA%A9%D8%AA%D8%A7%D9%85%DB%8C%D8%AF" title="نیکتامید – South Azerbaijani" lang="azb" hreflang="azb" data-title="نیکتامید" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Nikethamid" title="Nikethamid – German" lang="de" hreflang="de" data-title="Nikethamid" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Niquetamida" title="Niquetamida – Spanish" lang="es" hreflang="es" data-title="Niquetamida" data-language-autonym="Español" data-language-local-name="Spanish" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Niketamido" title="Niketamido – Esperanto" lang="eo" hreflang="eo" data-title="Niketamido" data-language-autonym="Esperanto" data-language-local-name="Esperanto" class="interlanguage-link-target"><span>Esperanto</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%86%DB%8C%DA%A9%D8%AA%D8%A7%D9%85%DB%8C%D8%AF" title="نیکتامید – Persian" lang="fa" hreflang="fa" data-title="نیکتامید" data-language-autonym="فارسی" data-language-local-name="Persian" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Nic%C3%A9thamide" title="Nicéthamide – French" lang="fr" hreflang="fr" data-title="Nicéthamide" data-language-autonym="Français" data-language-local-name="French" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D4%BF%D5%B8%D6%80%D5%A4%D5%AB%D5%A1%D5%B4%D5%AB%D5%B6" title="Կորդիամին – Armenian" lang="hy" hreflang="hy" data-title="Կորդիամին" data-language-autonym="Հայերեն" data-language-local-name="Armenian" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Niketamide" title="Niketamide – Italian" lang="it" hreflang="it" data-title="Niketamide" data-language-autonym="Italiano" data-language-local-name="Italian" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Niketamid" title="Niketamid – Norwegian Bokmål" lang="nb" hreflang="nb" data-title="Niketamid" data-language-autonym="Norsk bokmål" data-language-local-name="Norwegian Bokmål" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Niketamid" title="Niketamid – Polish" lang="pl" hreflang="pl" data-title="Niketamid" data-language-autonym="Polski" data-language-local-name="Polish" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Niquetamida" title="Niquetamida – Portuguese" lang="pt" hreflang="pt" data-title="Niquetamida" data-language-autonym="Português" data-language-local-name="Portuguese" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9D%D0%B8%D0%BA%D0%B5%D1%82%D0%B0%D0%BC%D0%B8%D0%B4" title="Никетамид – Russian" lang="ru" hreflang="ru" data-title="Никетамид" data-language-autonym="Русский" data-language-local-name="Russian" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Niketamid" title="Niketamid – Serbian" lang="sr" hreflang="sr" data-title="Niketamid" data-language-autonym="Српски / srpski" data-language-local-name="Serbian" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Niketamid" title="Niketamid – Serbo-Croatian" lang="sh" hreflang="sh" data-title="Niketamid" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="Serbo-Croatian" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Niketamidi" title="Niketamidi – Finnish" lang="fi" hreflang="fi" data-title="Niketamidi" data-language-autonym="Suomi" data-language-local-name="Finnish" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link 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screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox" style="border-spacing:2px;"><caption class="infobox-title"><span title="International nonproprietary name (INN): Nikethamide">Nikethamide</span></caption><tbody><tr><td colspan="2" class="infobox-image notheme" style="background-color: #f8f9fa;"><span typeof="mw:File"><a href="/wiki/File:Nikethamide.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/1/13/Nikethamide.svg/150px-Nikethamide.svg.png" decoding="async" width="150" height="105" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/13/Nikethamide.svg/225px-Nikethamide.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/13/Nikethamide.svg/300px-Nikethamide.svg.png 2x" data-file-width="512" data-file-height="357" /></a></span></td></tr><tr><td colspan="2" class="infobox-image notheme" style="background-color: #f8f9fa;"><span typeof="mw:File"><a href="/wiki/File:Nikethamide_molecule_ball.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a0/Nikethamide_molecule_ball.png/150px-Nikethamide_molecule_ball.png" decoding="async" width="150" height="119" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a0/Nikethamide_molecule_ball.png/225px-Nikethamide_molecule_ball.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a0/Nikethamide_molecule_ball.png/300px-Nikethamide_molecule_ball.png 2x" data-file-width="2000" data-file-height="1589" /></a></span></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Clinical data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;">Other names</th><td class="infobox-data">Nicotinic acid diethylamide</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/American_Society_of_Health-System_Pharmacists" title="American Society of Health-System Pharmacists">AHFS</a>/<a href="/wiki/Drugs.com" title="Drugs.com">Drugs.com</a></th><td class="infobox-data"><span title="www.drugs.com"><a rel="nofollow" class="external text" href="https://www.drugs.com/international/nikethamide.html">International Drug Names</a></span></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Anatomical_Therapeutic_Chemical_Classification_System" title="Anatomical Therapeutic Chemical Classification System">ATC code</a></th><td class="infobox-data"><style data-mw-deduplicate="TemplateStyles:r1126788409">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style><div class="plainlist"><ul><li><a href="/wiki/ATC_code_R07" title="ATC code R07">R07AB02</a>&#x20;(<span title="www.whocc.no"><a rel="nofollow" class="external text" href="https://www.whocc.no/atc_ddd_index/?code=R07AB02">WHO</a></span>)&#x20;</li></ul></div></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd"><a href="/wiki/Pharmacokinetics" title="Pharmacokinetics">Pharmacokinetic</a> data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Biological_half-life" title="Biological half-life">Elimination <span class="nowrap">half-life</span></a></th><td class="infobox-data">0.5 h</td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Identifiers</th></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/IUPAC_nomenclature_of_chemistry" title="IUPAC nomenclature of chemistry">IUPAC name</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all; text-align:left; padding-left:1.5em; text-indent:-1.5em;"><li style="line-height: inherit; margin: 0"><div style="font-size: 97%;"><i>N</i>,<i>N</i>-Diethyl-3-pyridinecarboxamide</div></li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/CAS_Registry_Number" title="CAS Registry Number">CAS Number</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="commonchemistry.cas.org"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=59-26-7">59-26-7</a></span><sup>&#160;<span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/PubChem#CID" title="PubChem">PubChem</a> <span style="font-weight:normal"><abbr title="Compound ID">CID</abbr></span></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="pubchem.ncbi.nlm.nih.gov"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/5497">5497</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/DrugBank" title="DrugBank">DrugBank</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.drugbank.ca"><a rel="nofollow" class="external text" href="https://www.drugbank.ca/drugs/DB13655">DB13655</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.chemspider.com"><a rel="nofollow" class="external text" href="https://www.chemspider.com/Chemical-Structure.5296.html">5296</a></span><sup>&#160;<span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Unique_Ingredient_Identifier" title="Unique Ingredient Identifier">UNII</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="precision.fda.gov"><a rel="nofollow" class="external text" href="https://precision.fda.gov/uniisearch/srs/unii/368IVD6M32">368IVD6M32</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/KEGG" title="KEGG">KEGG</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.kegg.jp"><a rel="nofollow" class="external text" href="https://www.kegg.jp/entry/D07408">D07408</a></span><sup>&#160;<span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChEBI" title="ChEBI">ChEBI</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.ebi.ac.uk"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:134814">CHEBI:134814</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChEMBL" title="ChEMBL">ChEMBL</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.ebi.ac.uk"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chembl/explore/compound/ChEMBL2104607">ChEMBL2104607</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/CompTox_Chemicals_Dashboard" title="CompTox Chemicals Dashboard">CompTox Dashboard</a> <span style="font-weight:normal">(<abbr title="U.S. Environmental Protection Agency">EPA</abbr>)</span></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="comptox.epa.gov"><a rel="nofollow" class="external text" href="https://comptox.epa.gov/dashboard/chemical/details/DTXSID9046524">DTXSID9046524</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q902548#P3117" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ECHA_InfoCard" class="mw-redirect" title="ECHA InfoCard"><span title="echa.europa.eu">ECHA InfoCard</span></a></th><td class="infobox-data"><a rel="nofollow" class="external text" href="https://echa.europa.eu/substance-information/-/substanceinfo/100.000.380">100.000.380</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q902548#P2566" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Chemical and physical data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Chemical_formula" title="Chemical formula">Formula</a></th><td class="infobox-data"><span title="Carbon">C</span><sub>10</sub><span title="Hydrogen">H</span><sub>14</sub><span title="Nitrogen">N</span><sub>2</sub><span title="Oxygen">O</span></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Molar_mass" title="Molar mass">Molar mass</a></th><td class="infobox-data"><span class="nowrap"><span data-sort-value="7002178235000000000♠"></span>178.235</span>&#160;g·mol<sup>−1</sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;">3D model (<a href="/wiki/JSmol" class="mw-redirect" title="JSmol">JSmol</a>)</th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="chemapps.stolaf.edu (3D interactive model)"><a rel="nofollow" class="external text" href="https://chemapps.stolaf.edu/jmol/jmol.php?model=O%3DC%28N%28CC%29CC%29c1cccnc1">Interactive image</a></span></li></ul></div></td></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/Simplified_molecular-input_line-entry_system" class="mw-redirect" title="Simplified molecular-input line-entry system">SMILES</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">O=C(N(CC)CC)c1cccnc1</div></li></ul> </div></td></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/International_Chemical_Identifier" title="International Chemical Identifier">InChI</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">InChI=1S/C10H14N2O/c1-3-12(4-2)10(13)9-6-5-7-11-8-9/h5-8H,3-4H2,1-2H3<sup>&#160;<span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></div></li><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">Key:NCYVXEGFNDZQCU-UHFFFAOYSA-N<sup>&#160;<span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></div></li></ul> </div></td></tr><tr><td colspan="2" class="infobox-below"><style data-mw-deduplicate="TemplateStyles:r886047488">.mw-parser-output .nobold{font-weight:normal}</style><span class="nobold">&#160;&#160;<span class="reflink plainlinks nourlexpansion"><a class="external text" href="https://en.wikipedia.org/w/index.php?title=Special:ComparePages&amp;rev1=447430580&amp;page2=Nikethamide">(verify)</a></span></span></td></tr></tbody></table> <p><b>Nikethamide</b> is a <a href="/wiki/Stimulant" title="Stimulant">stimulant</a> which mainly affects the respiratory cycle. Widely known by its former trade name of <b>Coramine</b>, it was used in the mid-twentieth century as a medical countermeasure against <a href="/wiki/Tranquilizer" class="mw-redirect" title="Tranquilizer">tranquilizer</a> <a href="/wiki/Drug_overdose" title="Drug overdose">overdoses</a>, before the advent of endotracheal <a href="/wiki/Intubation" title="Intubation">intubation</a> and positive-pressure lung expansion. It is no longer commonly considered to be of value for such purposes. </p><p>In alternate terminology, it is known as <i>nicotinic acid diethylamide</i>, which meaningfully emphasizes its laboratory origins, and of which its common name is derived as a <a href="/wiki/Blend_word" title="Blend word">blend</a>. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Former_and_current_medical_use">Former and current medical use</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Nikethamide&amp;action=edit&amp;section=1" title="Edit section: Former and current medical use"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure class="mw-default-size mw-halign-left" typeof="mw:File/Thumb"><a href="/wiki/File:Box,_metal_(AM_2001.25.1277-1).jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/4/41/Box%2C_metal_%28AM_2001.25.1277-1%29.jpg/220px-Box%2C_metal_%28AM_2001.25.1277-1%29.jpg" decoding="async" width="220" height="190" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/41/Box%2C_metal_%28AM_2001.25.1277-1%29.jpg/330px-Box%2C_metal_%28AM_2001.25.1277-1%29.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/41/Box%2C_metal_%28AM_2001.25.1277-1%29.jpg/440px-Box%2C_metal_%28AM_2001.25.1277-1%29.jpg 2x" data-file-width="1609" data-file-height="1389" /></a><figcaption>Coramine injection kit from the World&#160;War&#160;II (<a href="/wiki/Auckland_War_Memorial_Museum" title="Auckland War Memorial Museum">Auckland War Memorial Museum</a>, New Zealand)</figcaption></figure><p> Coramine was used by suspected <a href="/wiki/Serial_killer" title="Serial killer">serial killer</a> <a href="/wiki/John_Bodkin_Adams" title="John Bodkin Adams">John Bodkin Adams</a> when treating patient <a href="/wiki/Gertrude_Hullett" class="mw-redirect" title="Gertrude Hullett">Gertrude Hullett</a>, whom he was suspected of <a href="/wiki/Murder" title="Murder">murdering</a>.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> However, the toxicity of nikethamide is quite low (<a href="/wiki/Median_lethal_dose" title="Median lethal dose">LD<sub style="font-size:-1">50</sub></a> rabbits 650&#160;mg/kg oral, LD<sub>50</sub> rats 240&#160;mg/kg subcutaneous). </p><p><a href="/wiki/Theodor_Morell" title="Theodor Morell">Theodor Morell</a>, <a href="/wiki/Adolf_Hitler" title="Adolf Hitler">Adolf Hitler</a>'s personal physician, would inject the German ruler with Coramine when Hitler was unduly sedated with barbiturates. In addition, Morell would use Coramine as part of an all-purpose "tonic" for Hitler.<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> </p><p>It is available as a short-acting <a href="/wiki/Over-the-counter_drug" title="Over-the-counter drug">over-the-counter drug</a> in several South American and European countries, combined with glucose in form of lozenges. It is especially useful for mountain climbers to increase endurance at high altitudes. Contraindications include <a href="/wiki/Hypertension" title="Hypertension">hypertension</a>, <a href="/wiki/Cardiovascular" class="mw-redirect" title="Cardiovascular">cardiovascular</a> pathologies and <a href="/wiki/Epilepsy" title="Epilepsy">epilepsy</a>.<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Use_in_sports">Use in sports</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Nikethamide&amp;action=edit&amp;section=2" title="Edit section: Use in sports"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>In some sports, nikethamide is listed by the <a href="/wiki/World_Anti-Doping_Agency" title="World Anti-Doping Agency">World Anti-Doping Agency</a> as a banned substance. <a href="/wiki/Jaime_Hu%C3%A9lamo" title="Jaime Huélamo">Jaime Huélamo</a> was stripped of his bronze medal at the <a href="/wiki/Cycling_at_the_1972_Summer_Olympics_%E2%80%93_Men%27s_individual_road_race" title="Cycling at the 1972 Summer Olympics – Men&#39;s individual road race">1972 Olympic individual cycling road race</a> after testing positive for Coramine.<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">&#91;</span>4<span class="cite-bracket">&#93;</span></a></sup> Croatian tennis player <a href="/wiki/Marin_%C4%8Cili%C4%87" title="Marin Čilić">Marin Čilić</a> was suspended from competition for nine months after he tested positive for nikethamide in April 2013.<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">&#91;</span>5<span class="cite-bracket">&#93;</span></a></sup> This ban was later reduced to four months after Cilic appealed and claimed he had unintentionally ingested it in a glucose tablet bought at a pharmacy.<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">&#91;</span>6<span class="cite-bracket">&#93;</span></a></sup> Polish <a href="/wiki/Kart" class="mw-redirect" title="Kart">kart</a> driver Igor Walilko was given a two-year ban, later reduced to eighteen months, from competition in 2010 due to testing positive for nikethamide after a win in <a href="/wiki/Germany" title="Germany">Germany</a> in July, 2010.<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup> </p><p>In July 2021, Swiss athlete and doctor <a href="/wiki/Kariem_Hussein" title="Kariem Hussein">Kariem Hussein</a> was positively tested for nikethamide, which he regularly uses during training. He missed the <a href="/wiki/2020_Summer_Olympics" title="2020 Summer Olympics">2020 Summer Olympics</a> in <a href="/wiki/Tokyo" title="Tokyo">Tokyo</a>, and was banned from competitions for nine months.<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">&#91;</span>8<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Nikethamide&amp;action=edit&amp;section=3" title="Edit section: See also"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Nicorandil" title="Nicorandil">Nicorandil</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Nikethamide&amp;action=edit&amp;section=4" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFCullen2006" class="citation book cs1">Cullen PV (2006). <i>A Stranger in Blood: The Case Files on Dr John Bodkin Adams</i>. London: Elliott &amp; Thompson. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a>&#160;<a href="/wiki/Special:BookSources/1-904027-19-9" title="Special:BookSources/1-904027-19-9"><bdi>1-904027-19-9</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=A+Stranger+in+Blood%3A+The+Case+Files+on+Dr+John+Bodkin+Adams&amp;rft.place=London&amp;rft.pub=Elliott+%26+Thompson&amp;rft.date=2006&amp;rft.isbn=1-904027-19-9&amp;rft.aulast=Cullen&amp;rft.aufirst=Pamela+V.&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ANikethamide" class="Z3988"></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDoyle2005" class="citation journal cs1">Doyle D (February 2005). <a rel="nofollow" class="external text" href="http://www.rcpe.ac.uk/journal/issue/journal_35_1/Hitler&#39;s_medical_care.pdf">"Adolf Hitler's medical care"</a> <span class="cs1-format">(PDF)</span>. <i>The Journal of the Royal College of Physicians of Edinburgh</i>. <b>35</b> (1): 75–82. <a href="/wiki/OCLC_(identifier)" class="mw-redirect" title="OCLC (identifier)">OCLC</a>&#160;<a rel="nofollow" class="external text" href="https://search.worldcat.org/oclc/49953788">49953788</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a>&#160;<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15825245">15825245</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=The+Journal+of+the+Royal+College+of+Physicians+of+Edinburgh&amp;rft.atitle=Adolf+Hitler%27s+medical+care&amp;rft.volume=35&amp;rft.issue=1&amp;rft.pages=75-82&amp;rft.date=2005-02&amp;rft_id=info%3Aoclcnum%2F49953788&amp;rft_id=info%3Apmid%2F15825245&amp;rft.aulast=Doyle&amp;rft.aufirst=D&amp;rft_id=http%3A%2F%2Fwww.rcpe.ac.uk%2Fjournal%2Fissue%2Fjournal_35_1%2FHitler%27s_medical_care.pdf&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ANikethamide" class="Z3988"></span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://www.toxcenter.de/stoff-infos/n/nikethamid.pdf">Nikethamid</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20110722003658/http://www.toxcenter.de/stoff-infos/n/nikethamid.pdf">Archived</a> 2011-07-22 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a>, III-3.3, Toxcenter</span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.news24.com/xArchive/Olympics2004/InsideTrack/Olympic-dopings-list-of-shame-20040824">"Olympic doping's list of shame"</a>. <i>News24Wire ·</i>. 24 August 2004.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=unknown&amp;rft.jtitle=News24Wire+%C2%B7&amp;rft.atitle=Olympic+doping%27s+list+of+shame&amp;rft.date=2004-08-24&amp;rft_id=https%3A%2F%2Fwww.news24.com%2FxArchive%2FOlympics2004%2FInsideTrack%2FOlympic-dopings-list-of-shame-20040824&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ANikethamide" class="Z3988"></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-5">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation news cs1"><a rel="nofollow" class="external text" href="https://www.bbc.co.uk/sport/0/tennis/24116444">"Marin Cilic: Croatian banned for nine months"</a>. <i><a href="/wiki/BBC_News" title="BBC News">BBC News</a></i>. 16 September 2013<span class="reference-accessdate">. Retrieved <span class="nowrap">16 September</span> 2013</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=BBC+News&amp;rft.atitle=Marin+Cilic%3A+Croatian+banned+for+nine+months&amp;rft.date=2013-09-16&amp;rft_id=https%3A%2F%2Fwww.bbc.co.uk%2Fsport%2F0%2Ftennis%2F24116444&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ANikethamide" class="Z3988"></span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-6">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation news cs1"><a rel="nofollow" class="external text" href="http://www.tennis.com/pro-game/2013/10/cilic-cleared-play-again-after-suspension-reduced/49565/#.UmqAnfmsiSo">"Cilic cleared to play again after suspension reduced"</a>. <i><a href="/wiki/Tennis_(magazine)" title="Tennis (magazine)">Tennis</a></i>. 25 October 2013<span class="reference-accessdate">. Retrieved <span class="nowrap">25 October</span> 2013</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=Tennis&amp;rft.atitle=Cilic+cleared+to+play+again+after+suspension+reduced&amp;rft.date=2013-10-25&amp;rft_id=http%3A%2F%2Fwww.tennis.com%2Fpro-game%2F2013%2F10%2Fcilic-cleared-play-again-after-suspension-reduced%2F49565%2F%23.UmqAnfmsiSo&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ANikethamide" class="Z3988"></span></span> </li> <li id="cite_note-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-7">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFWalilko2011" class="citation web cs1">Walilko I (22 September 2011). <a rel="nofollow" class="external text" href="http://www.fia.com/sites/default/files/basicpage/file/10-10-11c-WALILKO-Decision-CAS.pdf">"Decision of the Court of Arbitration for Sport"</a> <span class="cs1-format">(PDF)</span>. <i>FIA Anti-Doping Disciplinary Committee</i><span class="reference-accessdate">. Retrieved <span class="nowrap">23 July</span> 2016</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=unknown&amp;rft.jtitle=FIA+Anti-Doping+Disciplinary+Committee&amp;rft.atitle=Decision+of+the+Court+of+Arbitration+for+Sport&amp;rft.date=2011-09-22&amp;rft.aulast=Walilko&amp;rft.aufirst=Igor&amp;rft_id=http%3A%2F%2Fwww.fia.com%2Fsites%2Fdefault%2Ffiles%2Fbasicpage%2Ffile%2F10-10-11c-WALILKO-Decision-CAS.pdf&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ANikethamide" class="Z3988"></span></span> </li> <li id="cite_note-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-8">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1 cs1-prop-foreign-lang-source"><a rel="nofollow" class="external text" href="https://www.20min.ch/story/diese-lutschtablette-wurde-kariem-hussein-zum-verhaengnis-235882779074">"Diese Lutschtablette wurde Kariem Hussein zum Verhängnis"</a>. <i>20 Minuten</i> (in German). 2021-07-23.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=unknown&amp;rft.jtitle=20+Minuten&amp;rft.atitle=Diese+Lutschtablette+wurde+Kariem+Hussein+zum+Verh%C3%A4ngnis&amp;rft.date=2021-07-23&amp;rft_id=https%3A%2F%2Fwww.20min.ch%2Fstory%2Fdiese-lutschtablette-wurde-kariem-hussein-zum-verhaengnis-235882779074&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ANikethamide" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Nikethamide&amp;action=edit&amp;section=5" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Diseases_Database" title="Diseases Database">Diseases Database</a> (DDB): <a 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id="Other_respiratory_system_products_(R07)" style="font-size:114%;margin:0 4em">Other <a href="/wiki/Respiratory_system" title="Respiratory system">respiratory system</a> products (<a href="/wiki/ATC_code_R07" title="ATC code R07">R07</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Pulmonary_surfactant" title="Pulmonary surfactant">Lung surfactants</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Colfosceril_palmitate" title="Colfosceril palmitate">Colfosceril palmitate</a></li> <li><a href="/wiki/Dipalmitoylphosphatidylcholine" title="Dipalmitoylphosphatidylcholine">Dipalmitoylphosphatidylcholine</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Respiratory stimulants</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Almitrine" title="Almitrine">Almitrine</a></li> <li><a href="/wiki/Amiphenazole" title="Amiphenazole">Amiphenazole</a></li> <li><a href="/wiki/Bemegride" title="Bemegride">Bemegride</a></li> <li><a href="/wiki/Dimefline" title="Dimefline">Dimefline</a></li> <li><a href="/wiki/Doxapram" title="Doxapram">Doxapram</a></li> <li><a href="/wiki/Etamivan" title="Etamivan">Etamivan</a></li> <li><a href="/wiki/GAL-021" class="mw-redirect" title="GAL-021">GAL-021</a></li> <li><a href="/wiki/Mepixanox" title="Mepixanox">Mepixanox</a></li> <li><a class="mw-selflink selflink">Nikethamide</a></li> <li><a href="/wiki/Pentylenetetrazol" title="Pentylenetetrazol">Pentetrazol</a></li> <li><a href="/wiki/Prethcamide" title="Prethcamide">Prethcamide</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/5-HT4_receptor" title="5-HT4 receptor">5-HT4 receptor</a> agonists</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/BIMU8" title="BIMU8">BIMU-8</a></li> <li><a href="/wiki/Zacopride" title="Zacopride">Zacopride</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other agents for treating respiratory depression</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Ivacaftor" title="Ivacaftor">Ivacaftor</a> (+ <a href="/wiki/Lumacaftor/ivacaftor" title="Lumacaftor/ivacaftor">lumacaftor</a>, + <a href="/wiki/Tezacaftor" title="Tezacaftor">tezacaftor</a>, + <a href="/wiki/Elexacaftor/tezacaftor/ivacaftor" title="Elexacaftor/tezacaftor/ivacaftor">elexacaftor/tezacaftor</a>)</li> <li><a href="/wiki/Nitric_oxide" title="Nitric oxide">Nitric oxide</a></li> <li><a href="/wiki/BW373U86" title="BW373U86">BW373U86</a></li> <li><a href="/wiki/CX-546" title="CX-546">CX-546</a></li> <li><a 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