CINXE.COM

<!DOCTYPE html><html lang="en-US"><head><title>Just a moment...</title><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta http-equiv="X-UA-Compatible" content="IE=Edge"><meta name="robots" content="noindex,nofollow"><meta name="viewport" content="width=device-width,initial-scale=1"><style>*{box-sizing:border-box;margin:0;padding:0}html{line-height:1.15;-webkit-text-size-adjust:100%;color:#313131;font-family:system-ui,-apple-system,BlinkMacSystemFont,Segoe UI,Roboto,Helvetica Neue,Arial,Noto Sans,sans-serif,Apple Color Emoji,Segoe UI Emoji,Segoe UI Symbol,Noto Color Emoji}body{display:flex;flex-direction:column;height:100vh;min-height:100vh}.main-content{margin:8rem auto;max-width:60rem;padding-left:1.5rem}@media (width <= 720px){.main-content{margin-top:4rem}}.h2{font-size:1.5rem;font-weight:500;line-height:2.25rem}@media (width <= 720px){.h2{font-size:1.25rem;line-height:1.5rem}}#challenge-error-text{background-image:url(data:image/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHdpZHRoPSIzMiIgaGVpZ2h0PSIzMiIgZmlsbD0ibm9uZSI+PHBhdGggZmlsbD0iI0IyMEYwMyIgZD0iTTE2IDNhMTMgMTMgMCAxIDAgMTMgMTNBMTMuMDE1IDEzLjAxNSAwIDAgMCAxNiAzbTAgMjRhMTEgMTEgMCAxIDEgMTEtMTEgMTEuMDEgMTEuMDEgMCAwIDEtMTEgMTEiLz48cGF0aCBmaWxsPSIjQjIwRjAzIiBkPSJNMTcuMDM4IDE4LjYxNUgxNC44N0wxNC41NjMgOS41aDIuNzgzem0tMS4wODQgMS40MjdxLjY2IDAgMS4wNTcuMzg4LjQwNy4zODkuNDA3Ljk5NCAwIC41OTYtLjQwNy45ODQtLjM5Ny4zOS0xLjA1Ny4zODktLjY1IDAtMS4wNTYtLjM4OS0uMzk4LS4zODktLjM5OC0uOTg0IDAtLjU5Ny4zOTgtLjk4NS40MDYtLjM5NyAxLjA1Ni0uMzk3Ii8+PC9zdmc+);background-repeat:no-repeat;background-size:contain;padding-left:34px}@media (prefers-color-scheme:dark){body{background-color:#222;color:#d9d9d9}}</style><meta http-equiv="refresh" content="120"></head><body class="no-js"><div class="main-wrapper" role="main"><div class="main-content"><noscript><div class="h2"><span id="challenge-error-text">Enable JavaScript and cookies to continue</span></div></noscript></div></div><script>(function(){window._cf_chl_opt={cvId: '3',cZone: "publications.waset.org",cType: 'non-interactive',cRay: '913487e7ab889fd4',cH: '4LFUQ_huDG3nP_2r_71xBrfqshV.D8xR_4io8MPHt6c-1739782237-1.2.1.1-Isv3O6EvbxdotBqSktDNGIPGE4okA0kbXJ6getyS1FpyA0DphAaKCnWvqcUIN0Co',cUPMDTk: "\/abstracts\/search?q=rheumatoid%20arthritis&__cf_chl_tk=FPGLUskXwVNhPU0jvcJwRji.4nLEszxCYHoKCCg4TuM-1739782237-1.0.1.1-JXSREsiD6Knwlx._b.tbnFcMHY62NbUxfCYz2Wz6Z7A",cFPWv: 'b',cITimeS: '1739782237',cTTimeMs: '1000',cMTimeMs: '120000',cTplC: 0,cTplV: 5,cTplB: 'cf',cK: "",fa: "\/abstracts\/search?q=rheumatoid%20arthritis&__cf_chl_f_tk=FPGLUskXwVNhPU0jvcJwRji.4nLEszxCYHoKCCg4TuM-1739782237-1.0.1.1-JXSREsiD6Knwlx._b.tbnFcMHY62NbUxfCYz2Wz6Z7A",md: "oEDCpKkdgZk0jIPdY3QBzuZB10VO.zTnLcLeryD9SIo-1739782237-1.2.1.1-Qo4q0jzAeMQ3gRUdE1tIAiDHG.nhxqLEzRPaMvxY8NY9W7oVwHoHxVvQP.E9FTiH0zicIKMjCJF4lQlWU21lMxle.Nsluexysl3yS25K50Yf6apdWFf4tGchwSjqAReZBNOYgCuWXCYju.T0W9U8g3rRP98FK1lc1QAQ5yjx7VLxrNiPu2ULjmdQ9F5qaF7xkpHm8x4HlCdURwFqo2xDWm_cLFqNXO5bhDyOzYIPLHqZm_hGJB89zKzpOPUh6CGBOzigKh66MxgwNcQEY9H3p8bsKo7hspA7IVn.J0fqk7XfuZR2zfRqcXbrWyVmLvFyTqIxC9rucays6F3nlwNUFR4AoJtNyjxwmZPODSe9AWidglLypSnZoYvYCYlOSs5zqn.dDwOI961EmBPMQS9gMbk7BjPMrk5cwAsEjj5FeMdJeAU4uur6kg7O7XwZqhfgFUzuPaRRYkgpAavHljiXZyQBSlgynoljJ1pHk0F.zPap.wqc3UeorSP95ydLi5vhSdvML00arPlv5fAoC3jHkIjHhHjEsBZawnTl7BkZHJHcU8QeZmYHqShWCH38A11BDqFMzWTCOf8R48EPvd6CWsjudgZNAUDcf8fudGB4xffF5dQsD9iR0ytO3AVplw955TPE03f1eQaBv.p4C1ixqDP5j70s3LGm9tyKhjCn_IFdWAXsXziaFFFosweBOyz3j7LGjtBz_NGMkF.c1owiv6t.c4nIkc3SysLeBznNoZlEW3B5NE8ybFLbSk0xvchsCFx4zrZSaRzJf1qruq5AAYNnGLTODYFmpKIns6mKmVyFAGG6U.iboKUGD.aMxVd7Q4z3Hq9a.yaE57CO5qcBTYibsxygHqs65UF4COwQvKwhKfoSWu73l9yVZB3XUXnOFKfsKLq5OUm_4TW_VRZ3KCCtVgbaDp81kw0uzUyXdYuXALmniSCQAmy_ExUqvEnatymVsJRslFXz2HNPhZqs43WdFlS1OLWmQsrdlIKHB7elQ3.NtbDzeVF5u4PiMbVZAorP087qUFD3wU.6BY4XEhoh.Aqdjz1GUl_go2Z1zV_6Vzh9TsLXG64wcXh2e8pCgEtKevsNmIeOEYQFMm.cCU1xEVaf26yNCbdhlij2PZdiVHBaUkIH34OsaEsmUktyfBnn.sMol_CXW.RMztp.twJRvXNO1v9ByMSAqV0Mpy37TZnTsYrCWrQ6oQUJmMI0juW2kv13A9Byq3rpARescmgDmgajfoNi3z8o7E3xjyV7q1oHkl3poHizzqSWc0VuoZflZ8Pk7fA3hu1CwPhn8SDKoupiqcglEjyvAyOiBZ.BeatmkOleeJe7bKqljIX8uvypdey7Dt4u7bpaz9BOuB6uYlHRXHEis66R7caZNgYEbMS9PTxhUS8Gfg.mMh0gFImURKqIPlHYDvzagY0ypSlgAXZ4h4z1Nxu1.lUFSmqx3rrVY6PWSwOHYRmK03OTE8.oXwUZb8b.nm82yxkA5uW4YDX.50sZeMjSvudVW_Adhc7NXAVwN6dyZuRenxSAbopBYo7UBXBtWysLdtrUwtCzIlETVZKjjjZZGbX0UtBTEGen6wQOtyN0FUUDQNKSwhj654k20DdND8vJlgg7cTvRs9TsC3ILeM.Z.Kz5yvhjrbeR78yrwntnEBzMo9hcWIwHeAaDYMOE8dwF.e6pZ.ftriqsq6PmC4T75XMcbMaiKyHqOXh7LEdzQx1vad0xIzqmcR6Fb0uaDme3qgHRKxW.Ynl3RC42ivH7Ci5G8AgrA7Av6xMyi4OWLz1.1H0SK7aMj3JSRJLerCt0.P_gQ2qeTQq_v86tehx9niuf9swUlqHN.1oh.6QIVpL5DbCX62P54aT034u1mUAqAFKKc1tbISHCtirBQoEnr_FRBvGY1OrXU7e9CMBfdr0UVXJ0BdacyepFTnwPzNofBRWUz27juJzjLVl.mZdPcG.MMwYVx0HlLDcTW.zodrvno19T",mdrd: "xXsY7LjTjTNnhEC51CIvuD5eIRblHUT6AQBxbEbQKiA-1739782237-1.2.1.1-H7YVZdnWpMLEpRgLi1Kwsj6sEmSTRP6eoqZueKhrKT9l5yRqbOw51LJ4gwskKvolRJeiLPc8kZNr0ZyRISwjbnrC8g_u_BtbHecC.y3kqOn5o3_du5Bw2XdS9qigQd.HLcQAdxz6Xd9SppXaH5vLEQjulm27d1cu4ThtK7qWYgDbb_r4lnTAD25nb4auQyXcYD7ifAqgWuok5HxM0C1mJs3FfO_oqyZC.byNa7hGPuRBadeZZ3rlNk_641bH9kVVMvCmWz77o6pSJJI22SB327JytPrOWdHtLyh4FEtkpZY1d8rVExXVfBN7o.2Zb_.65UmA0CzAdC3Jnc1oKg0S6d6xmbtqkjQtanjPTNgiqfuvPgTBVy302hwQrkGfrezkCFt2GbYITQTaQB8IzvVxyn3IXkSdnELXwOyfWSEsV0l1C4erahQIL5NdVj51kQ4VKZ1ntWsZf1T9coVjYQQONp3E7y6VYfGBM78PeYqLPxEXwQyPQFmmHNhSGX91q4uurbHlWGoC.hcKV4WkpvS52RAJU6kl1ii1GG33MY0vr8ddWF4EacwkuPjWpH0fpPzoo.SAJLsf7qikGwNfyxS2qeTlqV15tgHChqTSbJbjRkr9b5uVOA_2YILOweX.ndSC7u780Pjy1eXza7qfFlUWTqYS3xhYAZRjBDjGKWItPW0i58xQznd8tV1uCU0pSmTU.IEIb4oV7A_tVtmaujporkD.NsEOVyu2GeBjWBne41EFo_AsiD.sLlppHXIW1r4fES99.8qxijqXj85ANYaIyBNtTdx4A_Ivzfv7wWQ92t6kpsB5tPx12ooMeXRS7s78wkJQCl9rK12iftClPRV7d5hTsaifAOycsg9ZcV.jaGM_4qqFCdgf35rXFQWRz0bEQUysEiCwyP5xHCuBzuJUj0uDz3g6WfGnRmkOTkUTbfAxmkJcVutPAUio1nbcVVhYxh5SiRdslSSf2qKUjQ7IAPyciJ_whlVFGtfo8wuJaco5q_.Q4otoZLs6tgwN36bopVPyHA50MX5YCUX2V.B6jY7iuha8eHLgc5ihFtWk2CEoaNF8WMBVGOCQaetCXsMYiKelYVwWbZwEPVMLNzBit6yotLcuhm.5VuWfezzXLwqJGT4iCbcBNX.FvSgXYoJDFftEbhrsZpMIhAQid6CzhO2tS.t4ZUAtJevM2KbkSkXS76dtZIqZrzaL1JS5GgWnLN1Ytfa8IFDuQRfkTACJ5O3lJZ0JWRPnipRQVlLbz2IRDYzclC4JSBGHaO9yj5q3WmnWk8ZR5jZiGpt.IjxQUNSkTod.srccWE2Ghw4a4sAuQL.bPj8v7TThbAR5LRrbgDIbBiIiTidOBjo3RWY8fkGOiijmcPQD1ALxWd60tSoCE9L5oqRIU1og_xcItTGyozAhgSI38_eUDy6rsiUB70SV1GGAbuKRo3lezw6bQiWqDd6yp80mFQd7VQiSO6OhO_425LOk1etYczPD1FeTWdFMPcTbA3olFrF9hCNJ6ZoFBiWcOCaX1BQvYPit7NFvrx6VeF9KsSpC21bF3d5OoSrwQN3tM0YkDQUapL.1WycZ5vmgHecH7sKCJBiwgUn1a0h2mK5XzIRq1lSt4SvkTyE11sTPXuGujW3DovOX4nVWMPoFHHUp6ImO.g0z4LABwjVJvqT3tke4BCldlzj_81h8caof.zzeAiAjitVbYPyB4ZI8N_82LnXu.tvie4YftkGb3cd1w68jic80WuDN0MFdIYQnwBcxEMkmYknThfIy84xjsf7nXgdYsmqpFIL1QTJcvvFxUdCeaaqr_7ujjDtqqG.a8WNntOCQM_gpMmX5QPaJ0PpUc3yIaBt_3psxRU7JIoRFxjMu0kOym_IKVS1RNBCnCdDhLzcDZXRPsys7skx0wwtIOo3gagZ.1QU5ydDjp7TnbQqpZ9hliuiTSndOXKKJdOv91HPX3YdHkdeVrx5eD..udVl1OuxSSrwdhKcTIUKnNapqOvA84EWkwg"};var cpo = document.createElement('script');cpo.src = '/cdn-cgi/challenge-platform/h/b/orchestrate/chl_page/v1?ray=913487e7ab889fd4';window._cf_chl_opt.cOgUHash = location.hash === '' && location.href.indexOf('#') !== -1 ? '#' : location.hash;window._cf_chl_opt.cOgUQuery = location.search === '' && location.href.slice(0, location.href.length - window._cf_chl_opt.cOgUHash.length).indexOf('?') !== -1 ? '?' : location.search;if (window.history && window.history.replaceState) {var ogU = location.pathname + window._cf_chl_opt.cOgUQuery + window._cf_chl_opt.cOgUHash;history.replaceState(null, null, "\/abstracts\/search?q=rheumatoid%20arthritis&__cf_chl_rt_tk=FPGLUskXwVNhPU0jvcJwRji.4nLEszxCYHoKCCg4TuM-1739782237-1.0.1.1-JXSREsiD6Knwlx._b.tbnFcMHY62NbUxfCYz2Wz6Z7A" + window._cf_chl_opt.cOgUHash);cpo.onload = function() {history.replaceState(null, null, ogU);}}document.getElementsByTagName('head')[0].appendChild(cpo);}());</script></body></html>